CN101095886B - Chinese traditional medicine for treating heart neurosis and method for preparing the same - Google Patents
Chinese traditional medicine for treating heart neurosis and method for preparing the same Download PDFInfo
- Publication number
- CN101095886B CN101095886B CN2007100724338A CN200710072433A CN101095886B CN 101095886 B CN101095886 B CN 101095886B CN 2007100724338 A CN2007100724338 A CN 2007100724338A CN 200710072433 A CN200710072433 A CN 200710072433A CN 101095886 B CN101095886 B CN 101095886B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- portions
- cinnabaris
- heart neurosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Disclosed is a Chinese medicament for treating heart neurosis and its preparing process, wherein the raw materials include poria with hostwood, cinnabar, scrophularia root, bamboo leaves, pilose asiabell root, amber, astragalus root, oyster shell, pinellia tuber, cardamom, licorice root, polygala root, prepared rehmannia root, Chinese angelica root and baikal skullcap root. The preparing processconsists of disintegrating cinnabar and oyster into fines, making medicinal powders and mixing homogeneously.
Description
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof.
Background technology
Heart neurosis belongs to the disease of a kind of cardiac nerve aspect, is equivalent to the cardiopalmus of the traditional Chinese medical science, the timidness due to deficiency of the heart type, and main disease has: cardiopalmus, susceptible to fright and fear, uneasy in either sitting or lying, little sleep disturbed by dreams, thin white fur of tongue or as usual, moving number of pulse condition or empty string.This type state of an illness is than the lighter, and time ends when sending out, and weight person's palpitation with a distress feeling is not peaceful, finds it hard to concentrate, can not be autonomous.Patient's misery very, but in clinical examination, can not find out the foundation of organic disease, diagnosis and treatment difficulty very, prior treatment method is to take hypnotic sedative activity to the patient, but effect is but very undesirable, treatment back patient shows effect repeatedly, and uses hypnotic sedative activity can produce toxic and side effects for a long time, and patient's body is caused very big injury.
Summary of the invention
The objective of the invention is for the medication effect difference that solves existing treatment heart neurosis and to the problem of human body toxic side effect, and proposed a kind of Chinese medicine for the treatment of heart neurosis and preparation method thereof.A kind of Chinese medicine for the treatment of heart neurosis is made by 65～75 parts of Poria cum Radix Pinis, 6～11 parts of Cinnabaris, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 portions of Concha Ostreaes, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes according to ratio of weight and number.A kind of preparation method of Chinese medicine for the treatment of heart neurosis realizes by following steps: one, count by weight, it is standby to adopt elutriation to be ground into 100～200 purpose fine powders in 6～11 parts of Cinnabaris, and it is standby again 95～110 portions of Concha Ostreaes to be worn into 100～200 purpose fine powders with ball mill; Two, wear into 100～200 purpose fine powders after by weight 65～75 parts of Poria cum Radix Pinis, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes fully being mixed, obtain the medical material powder; Three, medical material powder and Concha Ostreae powder are fully mixed after again with Cinnabaris powder facing-up, sieve, mixing is even, promptly obtains a kind of Chinese medicine for the treatment of heart neurosis.The Chinese medicine of the treatment heart neurosis among the present invention is selected pure Chinese medicinal preparation for use, nontoxic to human body, a kind of Chinese medicine for the treatment of heart neurosis of the present invention's preparation, strengthening vital QI to eliminate pathogenic factors focuses on YIN nourishing and QI supplementing, clearing heart fire, the mind calming Fructus Alpiniae Oxyphyllae, tranquillization with heavy prescription makes the motive and and refreshing self-evident, painstaking effort are sufficient and refreshing from hiding.The present invention treat the heart neurosis therapeutic effect good, do not recur, treating both the principal and secondary aspects of a disease, to effect a permanent cure be main, adheres to taking getting final product clinical cure in 1～3 month, and relapse rate is low later on, only be 2～5%, effective percentage of the present invention is up to more than 95%, and cure rate reaches more than 85%.
The Chinese crude drug Radix Astragali of the present invention (Radix Astragali)---function cures mainly: give birth to and use: benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, poison holding, granulation promoting.Control spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and do not hold back for a long time.Moxibustion is used: invigorating the spleen and replenishing QI.Control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, and the card of all weakness of QI blood deficiency.
Radix Angelicae Sinensis---function cures mainly: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; Ulcer sores, injury from falling down.
Concha Ostreae---function cures mainly: yin fluid astringing, and YANG hyperactivity suppressing, hidroschesis, arresting seminal emission reduces phlegm, softening the hard mass.Zhi Jing Epilepsy is dazzle the eyes, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.
Radix Codonopsis---function cures mainly: invigorating middle warmer, QI invigorating is promoted the production of body fluid.Control weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.
Poria cum Radix Pini---function cures mainly: mind calming, calm the nerves diuretic.The palpitation with fear that is used to have a guilty conscience, forgetful, insomnia, infantile convulsion, dysuria.
Cinnabaris---function cures mainly: it is relieving convulsion to clear away heart-fire, the detoxifcation of calming the nerves.It is easily frightened to be used for heart neurosis, insomnia, and dreaminess, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.
Radix Scrophulariae---function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.Be used for the calentura deficiency of YIN, the crimson tongue excessive thirst, epidemic febrile disease is sent out speckle, and constipation is hindered in Tianjin, hectic fever due to YIN-deficiency phthisical cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Herba Lophatheri---function cures mainly: clearing heat and relieving fidgetness, diuresis.Be used for the calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Succinum---function cures mainly: tranquillizing and allaying excitement, relieving stranguria by diuresis, activating blood circulation to dissipate blood stasis.Be used for infantile convulsion, heart neurosis insomnia, dysuria, stranguria with blood pain in the penis, abdominalgia with blood stasis.
The Rhizoma Pinelliae---function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Be used for the abundant expectoration cough with asthma, the phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, the syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, and globus hystericus disease is given birth to external treatment carbuncle disease nuclear.
Fructus Amomi Rotundus---function cures mainly: the removing dampness painful abdominal mass that disappears, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.Be used for turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, the cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Radix Glycyrrhizae---function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, heart neurosis is breathed hard, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Polygalae---function cures mainly: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm detumescence.Be used for disarmony between the heart and kidney, insomnia and dreamful sleep, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Radix Rehmanniae Preparata---function cures mainly: nourishing YIN and supplementing blood, beneficial essence is filled out marrow.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, the heart neurosis palpitation with a distress feeling, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.
Radix Scutellariae---function cures mainly: heat clearing away removes dry, eliminating fire and detoxication, and hemostasis, antiabortive.Be used for hygropyrexia, fever disease in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The specific embodiment
The specific embodiment one: in the present embodiment a kind of Chinese medicine for the treatment of heart neurosis according to ratio of weight and number by 65～75 parts of Poria cum Radix Pinis, 6～11 parts of Cinnabaris, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 portions of Concha Ostreaes, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes are made.
Usage: a kind of Chinese medicine for the treatment of heart neurosis in the present embodiment is used for the treatment of heart neurosis, and a twice-daily when taking was taken after 30 minutes ante cibum of morning, the supper in 30 minutes, used warm boiled water, each 6g, and every is a course of treatment all around.
Table 1 is a kind of clinical pharmacodynamics report for the treatment of the treatment by Chinese herbs heart neurosis of heart neurosis among the present invention.
Heart neurosis patient at 25～62 years old treats to 30 example ages, and effective percentage is up to 95%, and cure rate is higher than 85%, and therapeutic effect is as shown in table 1, and wherein the diagnosis that regular hospital provides is accepted and believed in state of an illness diagnosis.
Diagnostic criteria is: the main disease had palpitation of heart neurosis, susceptible to fright and fear, uneasy in either sitting or lying, little sleep disturbed by dreams, thin white fur of tongue or as usual, moving number of pulse condition or empty string; The patient was treated 1～3 month, more than all transference cures be healing; 1～2 sx is arranged, and other transference cure or all symptoms all improve significantly, and are effectively; All symptoms do not disappear or do not have obviously improve be invalid.
Table 1
| Sequence number | Age | Sex | Disease | Use medicine (moon) | Therapeutic effect |
| 1 | 25 | The man | Heart neurosis | 1 | Cure |
| 2 | 38 | The woman | Heart neurosis | 3 | Cure |
| 3 | 46 | The woman | Heart neurosis | 3 | Cure |
| 4 | 60 | The man | Heart neurosis | 3 | Cure |
| 5 | 50 | The man | Heart neurosis | 3 | Cure |
| 6 | 44 | The man | Heart neurosis | 3 | Cure |
| 7 | 48 | The man | Heart neurosis | 2 | Cure |
| 8 | 44 | The man | Heart neurosis | 3 | Cure |
| 9 | 54 | The man | Heart neurosis | 3 | Cure |
| 10 | 51 | The man | Heart neurosis | 2 | Cure |
| 11 | 53 | The woman | Heart neurosis | 1 | Cure |
| 12 | 47 | The woman | Heart neurosis | 3 | Effectively |
| 13 | 42 | The woman | Heart neurosis | 3 | Effectively |
| 14 | 36 | The woman | Heart neurosis | 3 | Cure |
| 15 | 29 | The woman | Heart neurosis | 3 | Cure |
| 16 | 62 | The woman | Heart neurosis | 3 | Cure |
| Sequence number | Age | Sex | Disease | Use medicine (moon) | Therapeutic effect |
| 17 | 55 | The woman | Heart neurosis | 2 | Effectively |
| 18 | 49 | The man | Heart neurosis | 3 | Cure |
| 19 | 58 | The man | Heart neurosis | 2 | Cure |
| 20 | 39 | The woman | Heart neurosis | 3 | Cure |
| 21 | 49 | The man | Heart neurosis | 3 | Cure |
| 22 | 52 | The man | Heart neurosis | 3 | Cure |
| 23 | 48 | The man | Heart neurosis | 3 | Effectively |
| 24 | 53 | The man | Heart neurosis | 3 | Cure |
| 25 | 49 | The man | Heart neurosis | 2 | Cure |
| 26 | 60 | The man | Heart neurosis | 3 | Cure |
| 27 | 58 | The man | Heart neurosis | 3 | Effectively |
| 28 | 26 | The woman | Heart neurosis | 2 | Cure |
| 29 | 56 | The man | Heart neurosis | 3 | Effectively |
| 30 | 62 | The man | Heart neurosis | 2 | Cure |
The specific embodiment two: the difference of the present embodiment and the specific embodiment one be a kind of Chinese medicine for the treatment of heart neurosis according to ratio of weight and number by 66～73 parts of Poria cum Radix Pinis, 7～10 parts of Cinnabaris, 66～73 portions of Radix Scrophulariaes, 66～73 portions of Herba Lophatheris, 66～73 parts of Radix Codonopsis, 12～16 parts of succinums, 192～208 parts of Radixs Astragali, 97～108 portions of Concha Ostreaes, 97～108 parts of Rhizoma Pinelliaes, 97～108 portions of Fructus Amomi Rotunduss, 66～73 portions of Radix Glycyrrhizaes, 97～108 parts of Radix Polygalaes, 155～170 parts of Radix Rehmanniae Preparata, 128～137 parts of Radix Angelicae Sinensis and 128～137 parts of Radix Scutellariaes are made.
The specific embodiment three: the difference of the present embodiment and the specific embodiment one be a kind of Chinese medicine for the treatment of heart neurosis according to ratio of weight and number by 68～72 parts of Poria cum Radix Pinis, 7.5～9.5 parts of Cinnabaris, 67～72 portions of Radix Scrophulariaes, 67～72 portions of Herba Lophatheris, 67～72 parts of Radix Codonopsis, 13～15 parts of succinums, 195～205 parts of Radixs Astragali, 99～105 portions of Concha Ostreaes, 99～105 parts of Rhizoma Pinelliaes, 99～105 portions of Fructus Amomi Rotunduss, 67～72 portions of Radix Glycyrrhizaes, 99～105 parts of Radix Polygalaes, 158～167 parts of Radix Rehmanniae Preparata, 130～135 parts of Radix Angelicae Sinensis and 129～135 parts of Radix Scutellariaes are made.
The specific embodiment four: the difference of the present embodiment and the specific embodiment one be a kind of Chinese medicine for the treatment of heart neurosis according to ratio of weight and number by 69～71 parts of Poria cum Radix Pinis, 8～9 parts of Cinnabaris, 69～71 portions of Radix Scrophulariaes, 69～71 portions of Herba Lophatheris, 69～71 parts of Radix Codonopsis, 13.5～14.5 parts of succinums, 198～203 parts of Radixs Astragali, 101～104 portions of Concha Ostreaes, 101～104 parts of Rhizoma Pinelliaes, 101～104 portions of Fructus Amomi Rotunduss, 69～71 portions of Radix Glycyrrhizaes, 101～104 parts of Radix Polygalaes, 160～165 parts of Radix Rehmanniae Preparata, 132～134 parts of Radix Angelicae Sinensis and 130～134 parts of Radix Scutellariaes are made.
The specific embodiment five: the difference of the present embodiment and the specific embodiment one is that a kind of Chinese medicine for the treatment of heart neurosis made by 70 parts of Poria cum Radix Pinis, 8 parts of Cinnabaris, 70 portions of Radix Scrophulariaes, 70 portions of Herba Lophatheris, 70 parts of Radix Codonopsis, 14 parts of succinums, 201 parts of Radixs Astragali, 103 portions of Concha Ostreaes, 103 parts of Rhizoma Pinelliaes, 103 portions of Fructus Amomi Rotunduss, 70 portions of Radix Glycyrrhizaes, 103 parts of Radix Polygalaes, 163 parts of Radix Rehmanniae Preparata, 133 parts of Radix Angelicae Sinensis and 132 parts of Radix Scutellariaes according to ratio of weight and number.
The specific embodiment six: the difference of the present embodiment and the specific embodiment one is that a kind of Chinese medicine for the treatment of heart neurosis made by 68 parts of Poria cum Radix Pinis, 7 parts of Cinnabaris, 68 portions of Radix Scrophulariaes, 68 portions of Herba Lophatheris, 68 parts of Radix Codonopsis, 13 parts of succinums, 202 parts of Radixs Astragali, 101 portions of Concha Ostreaes, 101 parts of Rhizoma Pinelliaes, 101 portions of Fructus Amomi Rotunduss, 68 portions of Radix Glycyrrhizaes, 101 parts of Radix Polygalaes, 168 parts of Radix Rehmanniae Preparata, 136 parts of Radix Angelicae Sinensis and 136 parts of Radix Scutellariaes according to ratio of weight and number.
The specific embodiment seven: the difference of the present embodiment and the specific embodiment one is that a kind of Chinese medicine for the treatment of heart neurosis made by 67 parts of Poria cum Radix Pinis, 6 parts of Cinnabaris, 67 portions of Radix Scrophulariaes, 67 portions of Herba Lophatheris, 67 parts of Radix Codonopsis, 12 parts of succinums, 205 parts of Radixs Astragali, 107 portions of Concha Ostreaes, 106 parts of Rhizoma Pinelliaes, 105 portions of Fructus Amomi Rotunduss, 69 portions of Radix Glycyrrhizaes, 104 parts of Radix Polygalaes, 170 parts of Radix Rehmanniae Preparata, 139 parts of Radix Angelicae Sinensis and 138 parts of Radix Scutellariaes according to ratio of weight and number.
The specific embodiment eight: a kind of preparation method of Chinese medicine for the treatment of heart neurosis realizes by following steps in the present embodiment: one, count by weight, it is standby to adopt elutriation to be ground into 100～200 purpose fine powders in 6～11 parts of Cinnabaris, and it is standby again 95～110 portions of Concha Ostreaes to be worn into 100～200 purpose fine powders with ball mill; Two, wear into 100～200 purpose fine powders after by weight 65～75 parts of Poria cum Radix Pinis, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes fully being mixed, obtain the medical material powder; Three, medical material powder and Concha Ostreae powder are fully mixed after again with Cinnabaris powder facing-up, sieve, mixing, promptly obtain a kind of Chinese medicine for the treatment of heart neurosis.
The specific embodiment nine: it is standby that the difference of the present embodiment and the specific embodiment eight is to adopt elutriation to be ground into 120～180 purpose fine powders in 7～10 parts of Cinnabaris in the step 1, and it is standby again 97～108 portions of Concha Ostreaes to be worn into 120～180 purpose fine powders with ball mill.
The specific embodiment ten: it is standby that the difference of the present embodiment and the specific embodiment eight is to adopt elutriation to be ground into 130～170 purpose fine powders in 8.5～9.5 parts of Cinnabaris in the step 1, and it is standby again 100～105 portions of Concha Ostreaes to be worn into 130～170 purpose fine powders with ball mill.Other step is identical with the specific embodiment eight.
The specific embodiment 11: it is standby that the difference of the present embodiment and the specific embodiment eight is to adopt elutriation to be ground into 150 purpose fine powders in 9 parts of Cinnabaris in the step 1, and it is standby again 102 portions of Concha Ostreaes to be worn into 150 purpose fine powders with ball mill.Other step is identical with the specific embodiment eight.
The specific embodiment 12: the difference of the present embodiment and the specific embodiment eight is in the step 2 by weight with 66～73 parts of Poria cum Radix Pinis, 7～10 parts of Cinnabaris, 66～73 portions of Radix Scrophulariaes, 66～73 portions of Herba Lophatheris, 66～73 parts of Radix Codonopsis, 12～16 parts of succinums, 192～208 parts of Radixs Astragali, 97～108 portions of Concha Ostreaes, 97～108 parts of Rhizoma Pinelliaes, 97～108 portions of Fructus Amomi Rotunduss, 66～73 portions of Radix Glycyrrhizaes, 97～108 parts of Radix Polygalaes, 155～170 parts of Radix Rehmanniae Preparata, after fully mixing, 128～137 parts of Radix Angelicae Sinensis and 128～137 parts of Radix Scutellariaes wear into 120～180 purpose fine powders.Other step is identical with the specific embodiment eight.
The specific embodiment 13: the difference of the present embodiment and the specific embodiment eight is in the step 2 by weight with 68～72 parts of Poria cum Radix Pinis, 7.5～9.5 parts of Cinnabaris, 67～72 portions of Radix Scrophulariaes, 67～72 portions of Herba Lophatheris, 67～72 parts of Radix Codonopsis, 13～15 parts of succinums, 195～205 parts of Radixs Astragali, 99～105 portions of Concha Ostreaes, 99～105 parts of Rhizoma Pinelliaes, 99～105 portions of Fructus Amomi Rotunduss, 67～72 portions of Radix Glycyrrhizaes, 99～105 parts of Radix Polygalaes, 158～167 parts of Radix Rehmanniae Preparata, after fully mixing, 130～135 parts of Radix Angelicae Sinensis and 129～135 parts of Radix Scutellariaes wear into 120～180 purpose fine powders.Other step is identical with the specific embodiment eight.
The specific embodiment 14: present embodiment with wear into 120～180 purpose fine powders after the difference of the specific embodiment eight is by weight 68 parts of Poria cum Radix Pinis, 7 parts of Cinnabaris, 68 portions of Radix Scrophulariaes, 68 portions of Herba Lophatheris, 68 parts of Radix Codonopsis, 13 parts of succinums, 202 parts of Radixs Astragali, 101 portions of Concha Ostreaes, 101 parts of Rhizoma Pinelliaes, 101 portions of Fructus Amomi Rotunduss, 68 portions of Radix Glycyrrhizaes, 101 parts of Radix Polygalaes, 168 parts of Radix Rehmanniae Preparata, 136 parts of Radix Angelicae Sinensis and 136 parts of Radix Scutellariaes fully to be mixed in the step 2.Other step is identical with the specific embodiment eight.
For the drug safety of the Chinese medicine of the treatment heart neurosis of determining present embodiment, it has been done acute toxicity test, test unit is Heilongjiang University of Chinese Medicine institute of Chinese materia medica, test report is as follows:
One, material:
Be subjected to test product: the Chinese medicine of the treatment heart neurosis of present embodiment, what provide under, production technology fixing for writing out a prescription and the quality standard stable case is subjected to test product, is provided by Heilongjiang University of Chinese Medicine institute of Chinese materia medica.Every bag of 6g.
Animal: healthy Kunming kind white mice, body weight 20 ± 2 grams, male and female half and half are provided by Heilongjiang University of Chinese Medicine's Experimental Animal Center.
Two, method and result
1, give test: get 8 healthy mices and be divided into 2 groups at random, 4 every group, male and female half and half; Fasting 12 hours; To be subjected to test product mortar porphyrize, be made into the suspension of the Cmax 42% that can aspirate and 4.2% suspension, and once irritate stomach 1ml/20g for respectively two groups of mices with distilled water, observe one all two groups there is no death.Get 4 mices again, irritate with Cmax be subjected to the test product suspension, secondary is irritated stomach in 24 hours, 12 hours at interval, each 1ml/20g observed a week, does not see death.
2, every day maximum tolerated dose mensuration: get 20 of healthy mices, male and female half and half, the normal raising after 2 days, fasting 12 hours, 24 hours secondaries are irritated stomach and are subjected to test sample solution, the Cmax 42% of concentration for aspirating, each 1ml/20g, 12 hours at interval, one week of close observation, record mice active situation and death toll.
3, result: behind the gastric infusion, the mice general state is good, each mice activity freely, diet is normal, hair is glossy, the Excreta no abnormality seen is, none is only dead.The maximum tolerated dose multiple is calculated as follows:
The maximum tolerance of mice multiple=(mice dose every day/mice average weight) * (adult's average weight/adult's maximum every day dose)=[(2 * 42% * 1)/20]/[50000/ (2 * 5)]=210 (doubly)
Maximum tolerated dose be equivalent to be grown up 210 times of maximum dose every day can judge that the Chinese medicine of the treatment heart neurosis of present embodiment has no side effect in the above evidence, mice one day.
Claims (10)
1. a Chinese medicine for the treatment of heart neurosis is characterized in that being made by 65～75 parts of Poria cum Radix Pinis, 6～11 parts of Cinnabaris, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 portions of Concha Ostreaes, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes according to ratio of weight and number.
2. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 66～73 parts of Poria cum Radix Pinis, 7～10 parts of Cinnabaris, 66～73 portions of Radix Scrophulariaes, 66～73 portions of Herba Lophatheris, 66～73 parts of Radix Codonopsis, 12～16 parts of succinums, 192～208 parts of Radixs Astragali, 97～108 portions of Concha Ostreaes, 97～108 parts of Rhizoma Pinelliaes, 97～108 portions of Fructus Amomi Rotunduss, 66～73 portions of Radix Glycyrrhizaes, 97～108 parts of Radix Polygalaes, 155～170 parts of Radix Rehmanniae Preparata, 128～137 parts of Radix Angelicae Sinensis and 128～137 parts of Radix Scutellariaes according to ratio of weight and number.
3. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 68～72 parts of Poria cum Radix Pinis, 7.5～9.5 parts of Cinnabaris, 67～72 portions of Radix Scrophulariaes, 67～72 portions of Herba Lophatheris, 67～72 parts of Radix Codonopsis, 13～15 parts of succinums, 195～205 parts of Radixs Astragali, 99～105 portions of Concha Ostreaes, 99～105 parts of Rhizoma Pinelliaes, 99～105 portions of Fructus Amomi Rotunduss, 67～72 portions of Radix Glycyrrhizaes, 99～105 parts of Radix Polygalaes, 158～167 parts of Radix Rehmanniae Preparata, 130～135 parts of Radix Angelicae Sinensis and 129～135 parts of Radix Scutellariaes according to ratio of weight and number.
4. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 69～71 parts of Poria cum Radix Pinis, 8～9 parts of Cinnabaris, 69～71 portions of Radix Scrophulariaes, 69～71 portions of Herba Lophatheris, 69～71 parts of Radix Codonopsis, 13.5～14.5 parts of succinums, 198～203 parts of Radixs Astragali, 101～104 portions of Concha Ostreaes, 101～104 parts of Rhizoma Pinelliaes, 101～104 portions of Fructus Amomi Rotunduss, 69～71 portions of Radix Glycyrrhizaes, 101～104 parts of Radix Polygalaes, 160～165 parts of Radix Rehmanniae Preparata, 132～134 parts of Radix Angelicae Sinensis and 130～134 parts of Radix Scutellariaes according to ratio of weight and number.
5. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 70 parts of Poria cum Radix Pinis, 8 parts of Cinnabaris, 70 portions of Radix Scrophulariaes, 70 portions of Herba Lophatheris, 70 parts of Radix Codonopsis, 14 parts of succinums, 201 parts of Radixs Astragali, 103 portions of Concha Ostreaes, 103 parts of Rhizoma Pinelliaes, 103 portions of Fructus Amomi Rotunduss, 70 portions of Radix Glycyrrhizaes, 103 parts of Radix Polygalaes, 163 parts of Radix Rehmanniae Preparata, 133 parts of Radix Angelicae Sinensis and 132 parts of Radix Scutellariaes according to ratio of weight and number.
6. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 68 parts of Poria cum Radix Pinis, 7 parts of Cinnabaris, 68 portions of Radix Scrophulariaes, 68 portions of Herba Lophatheris, 68 parts of Radix Codonopsis, 13 parts of succinums, 202 parts of Radixs Astragali, 101 portions of Concha Ostreaes, 101 parts of Rhizoma Pinelliaes, 101 portions of Fructus Amomi Rotunduss, 68 portions of Radix Glycyrrhizaes, 101 parts of Radix Polygalaes, 168 parts of Radix Rehmanniae Preparata, 136 parts of Radix Angelicae Sinensis and 136 parts of Radix Scutellariaes according to ratio of weight and number.
7. a kind of Chinese medicine for the treatment of heart neurosis according to claim 1 is characterized in that being made by 67 parts of Poria cum Radix Pinis, 6 parts of Cinnabaris, 67 portions of Radix Scrophulariaes, 67 portions of Herba Lophatheris, 67 parts of Radix Codonopsis, 12 parts of succinums, 205 parts of Radixs Astragali, 107 portions of Concha Ostreaes, 106 parts of Rhizoma Pinelliaes, 105 portions of Fructus Amomi Rotunduss, 69 portions of Radix Glycyrrhizaes, 104 parts of Radix Polygalaes, 170 parts of Radix Rehmanniae Preparata, 139 parts of Radix Angelicae Sinensis and 138 parts of Radix Scutellariaes according to ratio of weight and number.
8. preparation method of Chinese medicine for the treatment of heart neurosis, it is characterized in that realizing: one, count by weight by following steps, it is standby to adopt elutriation to be ground into 100～200 purpose fine powders in 6～11 parts of Cinnabaris, and it is standby again 95～110 portions of Concha Ostreaes to be worn into 100～200 purpose fine powders with ball mill; Two, wear into 100～200 purpose fine powders after by weight 65～75 parts of Poria cum Radix Pinis, 65～75 portions of Radix Scrophulariaes, 65～75 portions of Herba Lophatheris, 65～75 parts of Radix Codonopsis, 11～17 parts of succinums, 190～210 parts of Radixs Astragali, 95～110 parts of Rhizoma Pinelliaes, 95～110 portions of Fructus Amomi Rotunduss, 65～75 portions of Radix Glycyrrhizaes, 95～110 parts of Radix Polygalaes, 150～175 parts of Radix Rehmanniae Preparata, 125～140 parts of Radix Angelicae Sinensis and 125～140 parts of Radix Scutellariaes fully being mixed, obtain the medical material powder; Three, medical material powder and Concha Ostreae powder are fully mixed after again with Cinnabaris powder facing-up, sieve, mixing, promptly.
9. a kind of preparation method of Chinese medicine for the treatment of heart neurosis according to claim 8, it is standby to it is characterized in that adopting elutriation to be ground into 120～180 purpose fine powders in 7～10 parts of Cinnabaris in the step 1, and it is standby again 97～108 portions of Concha Ostreaes to be worn into 120～180 purpose fine powders with ball mill.
10. a kind of preparation method of Chinese medicine for the treatment of heart neurosis according to claim 8 is worn into 120～180 purpose fine powders after it is characterized in that by weight 66～73 parts of Poria cum Radix Pinis, 7～10 parts of Cinnabaris, 66～73 portions of Radix Scrophulariaes, 66～73 portions of Herba Lophatheris, 66～73 parts of Radix Codonopsis, 12～16 parts of succinums, 192～208 parts of Radixs Astragali, 97～108 portions of Concha Ostreaes, 97～108 parts of Rhizoma Pinelliaes, 97～108 portions of Fructus Amomi Rotunduss, 66～73 portions of Radix Glycyrrhizaes, 97～108 parts of Radix Polygalaes, 155～170 parts of Radix Rehmanniae Preparata, 128～137 parts of Radix Angelicae Sinensis and 128～137 parts of Radix Scutellariaes fully being mixed in the step 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100724338A CN101095886B (en) | 2007-06-29 | 2007-06-29 | Chinese traditional medicine for treating heart neurosis and method for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100724338A CN101095886B (en) | 2007-06-29 | 2007-06-29 | Chinese traditional medicine for treating heart neurosis and method for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101095886A CN101095886A (en) | 2008-01-02 |
| CN101095886B true CN101095886B (en) | 2010-06-09 |
Family
ID=39010109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007100724338A Active CN101095886B (en) | 2007-06-29 | 2007-06-29 | Chinese traditional medicine for treating heart neurosis and method for preparing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101095886B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102205001B (en) * | 2011-05-25 | 2012-10-31 | 王延玲 | Traditional Chinese medicine for treating neuropathic heart disease |
| CN104489106A (en) * | 2014-11-23 | 2015-04-08 | 江苏天目湖南山竹海食品有限公司 | Sheep colostrum composite powder for patients with cardiac neurosis |
| CN104983911A (en) * | 2015-07-03 | 2015-10-21 | 包莉丽 | Drug used for treating cardiac neurosis |
| CN108514631A (en) * | 2018-07-03 | 2018-09-11 | 谢洁如 | A kind of drug and preparation method thereof for treating cardiac neurosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156608A (en) * | 1996-12-10 | 1997-08-13 | 艾津华 | Chinese medicine for treating nerve system disease and producing process thereof |
-
2007
- 2007-06-29 CN CN2007100724338A patent/CN101095886B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156608A (en) * | 1996-12-10 | 1997-08-13 | 艾津华 | Chinese medicine for treating nerve system disease and producing process thereof |
Non-Patent Citations (4)
| Title |
|---|
| 李思宁.中医学对心脏神经官能症的认识及治疗进展.中医研究17 6.2004,17(6),51-53. |
| 李思宁.中医学对心脏神经官能症的认识及治疗进展.中医研究17 6.2004,17(6),51-53. * |
| 董克玲等.心脏神经官能症中医药治疗近况.国医论坛17 4.2002,17(4),53-54. |
| 董克玲等.心脏神经官能症中医药治疗近况.国医论坛17 4.2002,17(4),53-54. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101095886A (en) | 2008-01-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102342992B (en) | Chinese medicinal composition for treating insomnia and preparation method of preparation thereof | |
| CN101797352B (en) | Chinese medicinal composition for treating lassitude hypodynamia and preparation method thereof | |
| CN104288644A (en) | Pharmaceutical composition for treating spleen deficiency and preparation method thereof | |
| CN105362650A (en) | Pharmaceutical composition for treating constipation and application method thereof | |
| CN101095886B (en) | Chinese traditional medicine for treating heart neurosis and method for preparing the same | |
| CN104740437A (en) | Traditional Chinese medicine composition for treating constipation and preparation method of traditional Chinese medicine composition | |
| CN101703686B (en) | Chinese medicinal composition for treating diabetes | |
| CN105031454A (en) | Medicine for treating pulmonary tuberculosis | |
| CN103432412B (en) | Medicament for treating hyperplasia of mammary glands and preparation method thereof | |
| CN104547622A (en) | Traditional Chinese medicine preparation for treating cataract and preparation method of traditional Chinese medicine preparation | |
| CN104274754A (en) | Traditional Chinese medicine composition for treating infantile enuresis and preparation method of traditional Chinese medicine composition | |
| CN103638234B (en) | A kind of Chinese medicine composition, preparation and preparation method thereof for the treatment of tinnitus | |
| CN101049374B (en) | Oral liquid for treating leucoderma, and preparation method | |
| CN102988639A (en) | Medicament for treating cervical spondylosis and preparation method of medicament | |
| CN103285211B (en) | Traditional Chinese medicine particles for treating pathological obesity and preparation method | |
| CN102018809B (en) | Externally applied traditional Chinese medicine composition for treating umbilical hernia and umbilical hernia treating bag containing lychee seed and rhizoma cimicifugae | |
| CN102626509B (en) | Traditional Chinese medicine composite for curing pediatric jaundice | |
| CN105288413A (en) | Medicine for treating infantile enuresis and preparation method thereof | |
| CN101596271B (en) | Medicament for treating suppurative otitis media and preparation method thereof | |
| CN104162000A (en) | Capsule for treating heart-kidney yin-yang deficiency syndrome and preparation method thereof | |
| CN103393927B (en) | Medicine for treating climacteric syndrome and preparation method thereof | |
| CN100415289C (en) | A Chinese traditional medicinal preparation for treatment of leukoderma | |
| CN102247584A (en) | Traditional Chinese medicine for treating kidney-deficiency vertigo and preparation method thereof | |
| CN105412561A (en) | Medicine for treating anhypnia | |
| CN103386083B (en) | A kind of pharmaceutical composition for the treatment of type ii diabetes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: ZHAN JISHENG Free format text: FORMER OWNER: ZHAN SHUSHEN Effective date: 20091113 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20091113 Address after: Dalian City, Tongluowan economic and Technological Development Zone No. 10 North Building 1 unit 402 post encoding: 116600 Applicant after: Zhan Jisheng Address before: No. 72, building seventeen, 8 clean room 402 postal district of Heilongjiang city of Harbin province Nangang encoding: 150080 Applicant before: Zhan Shusen |
|
| ASS | Succession or assignment of patent right |
Owner name: ZHAN SHUSEN Free format text: FORMER OWNER: ZHAN JISHENG Effective date: 20100330 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhan Shusen Inventor before: Zhan Jisheng |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 116600 402, UNIT 1, BUILDING NO.10,NORTH OF TONGLUOWAN MINGYUAN, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT ZONE,DALIAN CITY TO: 150080 402,DOOR 8, BUILDING 17, NO.72, QINGBIN ROAD, NANGANG DISTRICT, HARBIN CITY, HEILONGJIANG PROVINCE Free format text: CORRECT: INVENTOR; FROM: ZHAN JISHENG TO: ZHAN SHUSEN |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20100330 Address after: No. 72, building 17, Qing 8 door 402 Nangang District 150080 Harbin city of Heilongjiang Province Applicant after: Zhan Shusen Address before: The 116600 Dalian economic and Technological Development Zone, Tongluowan, No. 10 North Building 1 unit 402 Applicant before: Zhan Jisheng |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |