CN104983911A

CN104983911A - Drug used for treating cardiac neurosis

Info

Publication number: CN104983911A
Application number: CN201510389936.2A
Authority: CN
Inventors: 包莉丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-07-03
Filing date: 2015-07-03
Publication date: 2015-10-21

Abstract

The invention relates to a drug used for treating cardiac neurosis. The drug comprises, by weight, 12 parts of astragalus membranaceus, 9 parts of polygala tenuifolia, 6 parts of angelica sinensis, 9 parts of barbary wolfberry fruit and 6 parts of pseudo-ginseng. In the formula, the astragalus membranaceus has the effect of reinforcing vital energy; the polygala tenuifolia enters the heart channel and has the effect of quieting the heart and calming the nerves; the angelica sinensis has the effect of promoting blood circulation to remove blood stasis; the barbary wolfberry fruit has the effects of enriching yin and nourishing the kidney; the pseudo-ginseng has the effects of enriching the blood and activating the blood. The raw medicine is used in conjunction to treat cardiac neurosis, and as the drug takes effect, symptoms can basically vanish. Clinical trial prompts that the drug can be safely and effectively used for treating cardiac neurosis.

Description

A kind of medicine being used for the treatment of heart neurosis

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of Chinese medicine being used for the treatment of heart neurosis.

Background technology

Heart neurosis is the more special disease of one, and its Symptoms is in cardiovascular, respiratory system, but check result shows that again all are normal; Obviously patient feels very uncomfortable, is but exactly that disease is can not check in inspection.Since although most of doctor thinks that health is no problem, just need not manage it, patient feels very uncomfortable, sometimes also can cause depression, badly influences the study and work of patient.This disease is also called nerve hemasthenosis disease, anxiety neurosis etc.

Usually think after morbidity and oneself obtained heart disease or pneumonopathy, tell that the heart beating of doctor oneself is very irregular, the power of heartbeat is very large very apprehensively, or breathe effort.These symptoms are more obvious when peace and quiet, do not think on the contrary when busy, motion.Symptom be mainly summarized as following some: nervous, dyspnea: it is not enough that patient always feels to suck air, or think to feel oppressed in chest, thus need to breathe deeply or breathing as sign gas, precordialgia: be often apical region of heart and left inframammary region's twinge or lancinating pain, sometimes be that breast is vexed, dull pain, pain time is changeable, sometimes several seconds are only had, sometimes several hours are reached, autonomic nervous dysfunction's symptom: hyperhidrosis, brothers feel cold, two hand tremors, upper abdomen is swollen, stomachache, frequent micturition, times of defecation increases or just, tired, insomnia, insomnia-middle or dreaminess, low grade fever, inappetence, dizzy, headache, myalgia etc.

Modern medicine study is thought; systema cariovasculare functional is mainly by endocrine and neural dual regulation; what wherein play mastery reaction is autonomic nervous system; regulated the normal activity of cardiovascular system of human body by the mutual antagonism coordinative role between sympathetic nerve, vagus nerve, make cardiac electrophysiology maintain metastable state.Because various intense stimulus (such as disorder of emotion etc.) can cause cerebral cortex excitement and process of inhibition obstacle, cause the imbalance of maincenter and autonomic nervous function disorderly, cause sympathetic tone too high, finally causing cardiovascular function abnormal, often there is a series of clinical syndrome such as cardiopalmus, uncomfortable in chest, weak, the electrocardiogram ST-T changes, insomnia and dreamful sleep and precordialgia in patient.

Medical material involved in the present invention is all recorded in " Chinese Pharmacopoeia ".

Summary of the invention

The present invention aims to provide a kind of medicine being used for the treatment of heart neurosis, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to heart neurosis treatment.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a medicine for heart neurosis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 12 parts, Radix Polygalae 9 parts, Radix Angelicae Sinensis 6 parts, Fructus Lycii 9 parts, Radix Notoginseng 6 parts.

Inventor thinks, the symptom of Dalosta syndrome is similar to " cardiopalmus ", can treat with " cardiopalmus " category.The pathogenesis of cardiopalmus is: or by scaring excessively, the damage mind, causes the mind to be unbearably much troubled and is palpitation with fear; Or because of ferritic virtual loss, excessive asthenia, consumption impairment of QI blood, cannot moisten nourishing the heart to keep a sound mind, if ferritic fictitious pole, the high Sheng of pathogen, has palpitation without scaring, uncontrollable, then the palpitation with a distress feeling of meaning.Commonly encountered diseases that the traditional Chinese medical science is thought " cardiopalmus " because: ferritic is weak, improper diet and overtiredness, internal injury caused by excess of seven emotions, medicine food is improper, being invaded by exogenous pathogen etc., therefore the Therapeutic Principle of " cardiopalmus " is benefiting vital QI and blood, warming YANG tonify deficiency, nourishing the blood and yin, or be circulation of qi promoting of eliminating the phlegm, the mind calming that relieves inflammation or internal heat, dissipating fluid-retention clots absorbing.Radix Astragali strongly invigorating primordial QI in side, Radix Polygalae enters heart channel, mind tranquilizing and the heart calming, Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling, Fructus Lycii, enriching yin and nourishing kidney, and Radix Notoginseng, enriches blood and invigorate blood circulation.All medicines share, and treatment heart neurosis, can accomplish that As the medicine took effect, the symptoms lessened substantially.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, object and method

Inventor collects 108 routine patients in February, 2012 altogether by during in December, 2013, patient dependence is all good, can follow up a case by regular visits to check.

1.1 include case standard in

All patients are all through inspections such as detailed physical and chest x sheet, Color Sonography and conventional 12 lead electrocardiogram, and display exists ST-T and changes, and all give propanolol test and are shown as the positive (T ripple and s-T section recover normal).

1.2 Excluded cases

(1) get rid of the organic heart diseasies such as hyperthyroidism, myocarditis and coronary heart disease to become;

(2) chronic infection and drug influence person.

1.3 physical data

108 routine patients are divided into 2 groups at random, often organize 54 examples.Treatment group man 16 example, female 38 example, at minimum 23 years old of age, maximum 52 years old, average 34.5 years old, the course of disease was the shortest 5 months, the longest nearly 4 years; Matched group man 19 example, female 3 example.In age 24-51 year, 35.5 years old mean age, the course of disease is the shortest 6 months, the longest nearly 4.5 years.Compare physical data there was no significant difference, there is comparability for two groups.

2, research method

2.1 Therapeutic Method

Treatment group takes the decoct that the present invention obtains according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.

It is oral that matched group gives XINKESHU PIAN, takes according to its description.

All treat 3 months for two groups.

Meals feelings will is taken good care of oneself: light, easy to digest, less salt, low fat, restriction take in albumen quality, avoid strenuous exercise simultaneously, avoid serious anxious state of mind.

2.2 statistical method

Adopt SPSS18.0 statistics software data processing.

3, therapeutic outcome

3.1 criterion of therapeutical effect

Cure: classical symptom disappears, ECG results display is normal; Effective: classical symptom takes a turn for the better, and electrocardiogram recovers normal sometimes; Invalid: classical symptom and electrocardiogram are all without improvement.

3.2 liang of group curative effects

Two groups after treating 3 months, treatment group recovery from illness 8 example, effective 43 example, invalid 3 example, total effective rate is 94.4%; Matched group group recovery from illness 2 example, effective 31 examples, invalid 21 examples, total effective rate is 61.1%.There is significant significant difference in two groups of total effective rates, P < 0.05, and the evident in efficacy for the treatment of group is better than matched group.

3.3 untoward reaction

Over the course for the treatment of, there are dizzy 3 examples in matched group to patient, and each 1 example of cardiopalmus, hallucination, occur untoward reaction 5 example altogether, adverse reaction rate is 9.3%.Treatment group has no obvious adverse reaction.

Visible, the medicine that the present invention obtains can safe and effective treatment heart neurosis, has good medical science promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: the Radix Astragali 12 grams, Radix Polygalae 9 grams, Radix Angelicae Sinensis 6 grams, Fructus Lycii 9 grams, Radix Notoginseng 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of heart neurosis.Oral, every bu morning, noon and afternoon take for three times.

Embodiment 2

Take: the Radix Astragali 12 grams, Radix Polygalae 9 grams, Radix Angelicae Sinensis 6 grams, Fructus Lycii 9 grams, Radix Notoginseng 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of heart neurosis.Oral, daily once.

Embodiment 3

Take: the Radix Astragali 12 grams, Radix Polygalae 9 grams, Radix Angelicae Sinensis 6 grams, Fructus Lycii 9 grams, Radix Notoginseng 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of heart neurosis.Oral, every bu is taken for twice sooner or later.

Claims

1. be used for the treatment of a medicine for heart neurosis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 12 parts, Radix Polygalae 9 parts, Radix Angelicae Sinensis 6 parts, Fructus Lycii 9 parts, Radix Notoginseng 6 parts.