CN108514631A - A kind of drug and preparation method thereof for treating cardiac neurosis - Google Patents

A kind of drug and preparation method thereof for treating cardiac neurosis Download PDF

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Publication number
CN108514631A
CN108514631A CN201810711319.3A CN201810711319A CN108514631A CN 108514631 A CN108514631 A CN 108514631A CN 201810711319 A CN201810711319 A CN 201810711319A CN 108514631 A CN108514631 A CN 108514631A
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Prior art keywords
parts
radix
rhizoma
fruit
root
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CN201810711319.3A
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Chinese (zh)
Inventor
谢胜
刘园园
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Xie Jieru
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Xie Jieru
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Priority to CN201810711319.3A priority Critical patent/CN108514631A/en
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    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
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Abstract

The invention discloses a kind of drug and preparation method thereof for treating cardiac neurosis, the raw material for treating the drug of cardiac neurosis includes：The root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, stir-baked RHIZOMA POLYGONATI with yellow rice wine, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, donkey-hide gelatin, deer horn glue, Morinda officinalis, Herba Epimedii, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, ching-chieh, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, Chinese cassia tree, pawpaw, fructus amomi, teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong.The present invention treats based on invigorating spleen and soothing liver, filling liver kidney, replenishing essence blood, and adjusted comprehensively to each internal organs according to heart deficiency of the kidney void physique characteristic, actual situation is differentiated, constitution is biased, accomplishes that bowl spares has clearly, it mends without stagnant, comprehensive adjustment whole body qi and blood, negative and positive, reaches balance whole body negative and positive state.

Description

A kind of drug and preparation method thereof for treating cardiac neurosis
Technical field
The present invention relates to technical field of traditional Chinese medicines, the drug of specifically a kind for the treatment of cardiac neurosis and its preparation side Method.
Background technology
Cardiac neurosis（cardiac neurosis,CN）, also referred to as functional cardiac is uncomfortable, is by vegetative nerve One group of Spirit nerve symptoms of disease of heart and cardiovascular system dysfunction caused by functional disturbance, is frequently accompanied by the nerve at other positions of body Symptom.Patient's heart without organic disease, clinical cardinal symptom be feel depressed, chest expires bored, distending pain in the chest and hypochondrium, or easily cries The symptoms such as irritability.The operating pressure of modern society is big, and the incidence of CN is in the trend risen year by year, though this sick not threat to life, But the quality of life of patient is seriously affected.Traditional Chinese medicine thinks, CN patient mainly with palpitaition, precordialgia etc. for primary symptom, when Belong to the scopes such as traditional Chinese medicine " palpitaition " or " obstruction of qi in the chest ", in addition this disease morbidity again it is closely bound up with emotional factors, also can by " melancholia ", " hysteria " etc. carries out diagnosis and treatment.Chinese medicine thinks that the cause of disease is mostly the factors such as diet, feelings will, internal injury cause the heart to be become homeless foster, the dysfunction of the spleen in transport, liver Catharsis is lost, kidney loses envelope and hides, and it is CN to send out.Modern doctor mostly discusses disease of effecting a permanent cure from internal organs such as the heart, liver,spleen,kidneys, and the heart is main disease Position, originally for disease, liver, spleen are closely related therewith for kidney.Treatment doctor trained in Western medicine is mainly with drug control symptom to the treatment of the disease at present It is main, it is main using stable, oryzanol or（With）Based on the drug therapies such as beta-blocker, but effect is not very ideal, and Western medicine side effect is big, price increases the difficulty for treating this disease.The advantage of traditional Chinese medicine is more highlighted under these forms, Common traditional Chinese medicine for oral administration has a decoction and pill, and decoction decocting is cumbersome, poor taste, and patient compliance is poor, and pill absorbs, is effective Slowly, flavour of a drug dose is fixed, it is difficult to reach debate disease opinion control therapeutic effect.Based on upper, Chinese medicine is processed into herbal paste, not only can overcome the disadvantages that soup The deficiency of medicine and pill is also equipped with the advantage of decoction of medicinal ingredients and pill, and such as significant in efficacy, few side effects, patient compliance are good, carry storage Deposit conveniently, it is in good taste.
Invention content
The purpose of the present invention is to provide a kind of medicines of the few treatment cardiac neurosis of Small side effects, patient compliance Object and preparation method thereof, to solve the problems mentioned in the above background technology.
To achieve the above object, the present invention provides the following technical solutions：
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：8-12 parts of the root of bidentate achyranthes, psoralea corylifolia 12-18 Part, 28-32 parts of Os Draconis, 18-22 parts of Radix Paeoniae Alba, 12-18 parts of rhizoma atractylodis macrocephalae, 4.5-5.5 parts of campanulaceae, 12-18 parts of fructus alpiniae oxyphyllae, stir-baked RHIZOMA POLYGONATI with yellow rice wine 18-22 parts, 28-32 parts of Herba Cistanches, 4.5-5.5 parts of thizoma curculiginis, 18-22 parts of the seed of Oriental arborvitae, 4.5-5.5 parts of folium artemisiae argyi, Rhizoma Et Radix Notopterygii 4.5-5.5 Part, 28-32 parts of ginger carbon, 12-18 parts of lotus seeds, 28-32 parts of Chinese yam, 28-32 parts of amethyst, 12-18 parts of honey-fried licorice root, Poria cocos 12-18 Part, 4.5-5.5 parts of donkey-hide gelatin, 4.5-5.5 parts of deer horn glue, 18-22 parts of Morinda officinalis, 12-18 parts of Herba Epimedii, 18-22 parts of Radix Angelicae Sinensis, mountain cornel 18-22 parts of meat, 4.5-5.5 parts of fennel seeds, 4.5-5.5 parts of ching-chieh, 80-100 parts of radix rehmanniae preparata, 28-32 parts of Gorgon fruit, raw oyster 28- 32 parts, 18-22 parts of coix seed, 12-18 parts of Radix Codonopsis, 18-22 parts of Semen Lablab Album, 18-22 parts of Semen Cuscutae, 12-18 parts of mulberries, Chinese cassia tree 8- 12 parts, 28-32 parts of pawpaw, 8-12 parts of fructus amomi, 12-18 parts of teasel root, 12-18 parts of the fruit of Chinese wolfberry, 8-12 parts of semen allii tuberosi, Rhizoma Chuanxiong 8-12 Part.
As a further solution of the present invention：
It is described treatment cardiac neurosis drug, include according to the raw material of parts by weight：9-11 parts of the root of bidentate achyranthes, psoralea corylifolia 14-16 Part, 29-31 parts of Os Draconis, 19-21 parts of Radix Paeoniae Alba, 14-16 parts of rhizoma atractylodis macrocephalae, 4.8-5.2 parts of campanulaceae, 14-16 parts of fructus alpiniae oxyphyllae, stir-baked RHIZOMA POLYGONATI with yellow rice wine 19-21 parts, 29-31 parts of Herba Cistanches, 4.8-5.2 parts of thizoma curculiginis, 19-21 parts of the seed of Oriental arborvitae, 4.8-5.2 parts of folium artemisiae argyi, Rhizoma Et Radix Notopterygii 4.8-5.2 Part, 29-31 parts of ginger carbon, 14-16 parts of lotus seeds, 29-31 parts of Chinese yam, 29-31 parts of amethyst, 14-16 parts of honey-fried licorice root, Poria cocos 14-16 Part, 4.8-5.2 parts of donkey-hide gelatin, 4.8-5.2 parts of deer horn glue, 19-21 parts of Morinda officinalis, 14-16 parts of Herba Epimedii, 19-21 parts of Radix Angelicae Sinensis, mountain cornel 19-21 parts of meat, 4.8-5.2 parts of fennel seeds, 4.8-5.2 parts of ching-chieh, 85-95 parts of radix rehmanniae preparata, 29-31 parts of Gorgon fruit, raw oyster 29-31 Part, 19-21 parts of coix seed, 14-16 parts of Radix Codonopsis, 19-21 parts of Semen Lablab Album, 19-21 parts of Semen Cuscutae, 14-16 parts of mulberries, Chinese cassia tree 9-11 Part, 29-31 parts of pawpaw, 9-11 parts of fructus amomi, 14-16 parts of teasel root, 14-16 parts of the fruit of Chinese wolfberry, 9-11 parts of semen allii tuberosi, 9-11 parts of Rhizoma Chuanxiong.
As further scheme of the invention：
It is described treatment cardiac neurosis drug, include according to the raw material of parts by weight：10 parts of the root of bidentate achyranthes, 15 parts of psoralea corylifolia, life 30 parts of keel, 20 parts of Radix Paeoniae Alba, 15 parts of rhizoma atractylodis macrocephalae, 5 parts of campanulaceae, 15 parts of fructus alpiniae oxyphyllae, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 30 parts of Herba Cistanches, thizoma curculiginis 5 Part, 20 parts of the seed of Oriental arborvitae, 5 parts of folium artemisiae argyi, 5 parts of Rhizoma Et Radix Notopterygii, 30 parts of ginger carbon, 15 parts of lotus seeds, 30 parts of Chinese yam, 30 parts of amethyst, honey-fried licorice root 15 Part, 15 parts of Poria cocos, 5 parts of donkey-hide gelatin, 5 parts of deer horn glue, 20 parts of Morinda officinalis, 15 parts of Herba Epimedii, 20 parts of Radix Angelicae Sinensis, 20 parts of dogwood fruit, fennel fruit Fragrant 5 parts, 5 parts of ching-chieh, 90 parts of radix rehmanniae preparata, 30 parts of Gorgon fruit, 30 parts of raw oyster, 20 parts of coix seed, 15 parts of Radix Codonopsis, 20 parts of Semen Lablab Album, 20 parts of Semen Cuscutae, 15 parts of mulberries, 10 parts of Chinese cassia tree, 30 parts of pawpaw, 10 parts of fructus amomi, 15 parts of teasel root, 15 parts of the fruit of Chinese wolfberry, semen allii tuberosi 10 Part, 10 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 10-14h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 4-6h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 30-50min, cross 80 mesh and sieve 2-3 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
The seed of Oriental arborvitae, lotus seeds, Os Draconis, raw oyster, tortoise-shell glue, donkey-hide gelatin：Mental-tranquilization；
Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong：Blood-nourishing tune liver, soothing the liver promoting the circulation of qi；
Poria cocos, rhizoma atractylodis macrocephalae, Radix Codonopsis：Strengthening the spleen and replenishing qi, with angry blood；
Chinese yam, prepared rehmannia root, Fructus Corni, matrimony vine, mulberries：Mend nourishing liver and kidney；
Thizoma curculiginis, folium artemisiae argyi, Morinda officinalis, fennel seeds, Herba Epimedii, semen allii tuberosi：Warm sun mends bank；
Herba Cistanches, teasel root, stir-baked RHIZOMA POLYGONATI with yellow rice wine, Semen Cuscutae, psoralea corylifolia, fructus alpiniae oxyphyllae -- beneficial to spirit and marrow；
The root of bidentate achyranthes, amethyst, Chinese cassia tree：Guiding fire to origin；
Coix seed, fructus amomi, Rhizoma Et Radix Notopterygii, Semen Lablab Album, schizonepeta, campanulaceae, pawpaw, ginger carbon：Invigorating the spleen for eliminating dampness, promoting the circulation of qi are led stagnant；
Honey-fried licorice root：It replenishes qi to invigorate the spleen, emergency.
Compared with prior art, the beneficial effects of the invention are as follows：
The present invention treats based on invigorating spleen and soothing liver, filling liver kidney, replenishing essence blood, and complete to each internal organs according to heart deficiency of the kidney void physique characteristic Face is adjusted, and differentiates actual situation, and constitution is biased, is accomplished that bowl spares has clearly, is mended without stagnant, comprehensive adjustment whole body qi and blood, negative and positive reach flat Weigh whole body negative and positive state.It is controlled by debating disease opinion, to carrying out herbal paste intervention, dialectical selection present invention side carries out soothing liver and strengthening spleen, help Heart kidney, achievees the purpose that treatment.
Present invention is generally directed to the treatment of cardiac neurosis, due to the correlation of constitution, the starting point for the treatment of is from body Matter is started with, and the present invention can be also used for the nervous system diseases such as treatment neurosis, sleep disturbance, depressive disorder；It is intractable The disease of digestive systems such as gastroesophageal reflux disease, rectal prolapse, gastroptosis, functional abdominal pain；The andrologies such as seminal emission, impotence, premature ejaculation, infertility disease Disease；The gynecological diseases such as metroptosis, infertile；The ophthalmology diseases such as glaucoma, cataract, muscae volitantes；And chronic eczema, alopecia, The diseases such as degenerative arthritis, the protrasion of the lumbar intervertebral disci.
Description of the drawings
Fig. 1 is the medicine preparation flow diagram of the present invention.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Embodiment 1
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：8 parts of the root of bidentate achyranthes, 12 parts of psoralea corylifolia, raw dragon 28 parts of bone, 18 parts of Radix Paeoniae Alba, 12 parts of rhizoma atractylodis macrocephalae, 4.5 parts of campanulaceae, 12 parts of fructus alpiniae oxyphyllae, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 28 parts of Herba Cistanches, thizoma curculiginis 4.5 Part, 18 parts of the seed of Oriental arborvitae, 4.5 parts of folium artemisiae argyi, 4.5 parts of Rhizoma Et Radix Notopterygii, 28 parts of ginger carbon, 12 parts of lotus seeds, 28 parts of Chinese yam, 28 parts of amethyst, toast are sweet 12 parts of grass, 12 parts of Poria cocos, 4.5 parts of donkey-hide gelatin, 4.5 parts of deer horn glue, 18 parts of Morinda officinalis, 12 parts of Herba Epimedii, 18 parts of Radix Angelicae Sinensis, dogwood fruit 18 Part, 4.5 parts of fennel seeds, 4.5 parts of ching-chieh, 80 parts of radix rehmanniae preparata, 28 parts of Gorgon fruit, 28 parts of raw oyster, 18 parts of coix seed, 12 parts of Radix Codonopsis, 18 parts of Semen Lablab Album, 18 parts of Semen Cuscutae, 12 parts of mulberries, 8 parts of Chinese cassia tree, 28 parts of pawpaw, 8 parts of fructus amomi, 12 parts of teasel root, 12 parts of the fruit of Chinese wolfberry, 8 parts of semen allii tuberosi, 8 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 10h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 4h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 30min, cross 80 mesh and sieve 2 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 2
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：9 parts of the root of bidentate achyranthes, 14 parts of psoralea corylifolia, raw dragon 29 parts of bone, 19 parts of Radix Paeoniae Alba, 14 parts of rhizoma atractylodis macrocephalae, 4.8 parts of campanulaceae, 14 parts of fructus alpiniae oxyphyllae, 19 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 29 parts of Herba Cistanches, thizoma curculiginis 4.8 Part, 19 parts of the seed of Oriental arborvitae, 4.8 parts of folium artemisiae argyi, 4.8 parts of Rhizoma Et Radix Notopterygii, 29 parts of ginger carbon, 14 parts of lotus seeds, 29 parts of Chinese yam, 29 parts of amethyst, toast are sweet 14 parts of grass, 14 parts of Poria cocos, 4.8 parts of donkey-hide gelatin, 4.8 parts of deer horn glue, 19 parts of Morinda officinalis, 14 parts of Herba Epimedii, 19 parts of Radix Angelicae Sinensis, dogwood fruit 19 Part, 4.8 parts of fennel seeds, 4.8 parts of ching-chieh, 85 parts of radix rehmanniae preparata, 29 parts of Gorgon fruit, 29 parts of raw oyster, 19 parts of coix seed, 14 parts of Radix Codonopsis, 19 parts of Semen Lablab Album, 19 parts of Semen Cuscutae, 14 parts of mulberries, 9 parts of Chinese cassia tree, 29 parts of pawpaw, 9 parts of fructus amomi, 14 parts of teasel root, 14 parts of the fruit of Chinese wolfberry, 9 parts of semen allii tuberosi, 9 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 11h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 4.5h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 35min, cross 80 mesh and sieve 3 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 3
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：10 parts of the root of bidentate achyranthes, 15 parts of psoralea corylifolia, life 30 parts of keel, 20 parts of Radix Paeoniae Alba, 15 parts of rhizoma atractylodis macrocephalae, 5 parts of campanulaceae, 15 parts of fructus alpiniae oxyphyllae, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 30 parts of Herba Cistanches, thizoma curculiginis 5 Part, 20 parts of the seed of Oriental arborvitae, 5 parts of folium artemisiae argyi, 5 parts of Rhizoma Et Radix Notopterygii, 30 parts of ginger carbon, 15 parts of lotus seeds, 30 parts of Chinese yam, 30 parts of amethyst, honey-fried licorice root 15 Part, 15 parts of Poria cocos, 5 parts of donkey-hide gelatin, 5 parts of deer horn glue, 20 parts of Morinda officinalis, 15 parts of Herba Epimedii, 20 parts of Radix Angelicae Sinensis, 20 parts of dogwood fruit, fennel fruit Fragrant 5 parts, 5 parts of ching-chieh, 90 parts of radix rehmanniae preparata, 30 parts of Gorgon fruit, 30 parts of raw oyster, 20 parts of coix seed, 15 parts of Radix Codonopsis, 20 parts of Semen Lablab Album, 20 parts of Semen Cuscutae, 15 parts of mulberries, 10 parts of Chinese cassia tree, 30 parts of pawpaw, 10 parts of fructus amomi, 15 parts of teasel root, 15 parts of the fruit of Chinese wolfberry, semen allii tuberosi 10 Part, 10 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 12h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 5h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 40min, cross 80 mesh and sieve 3 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 4
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：11 parts of the root of bidentate achyranthes, 16 parts of psoralea corylifolia, life 31 parts of keel, 21 parts of Radix Paeoniae Alba, 16 parts of rhizoma atractylodis macrocephalae, 5.2 parts of campanulaceae, 16 parts of fructus alpiniae oxyphyllae, 21 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 31 parts of Herba Cistanches, thizoma curculiginis 5.2 parts, 21 parts of the seed of Oriental arborvitae, 5.2 parts of folium artemisiae argyi, 5.2 parts of Rhizoma Et Radix Notopterygii, 31 parts of ginger carbon, 16 parts of lotus seeds, 31 parts of Chinese yam, 31 parts of amethyst, toast 16 parts of Radix Glycyrrhizae, 16 parts of Poria cocos, 5.2 parts of donkey-hide gelatin, 5.2 parts of deer horn glue, 21 parts of Morinda officinalis, 16 parts of Herba Epimedii, 21 parts of Radix Angelicae Sinensis, dogwood fruit 21 parts, 5.2 parts of fennel seeds, 5.2 parts of ching-chieh, 95 parts of radix rehmanniae preparata, 31 parts of Gorgon fruit, 31 parts of raw oyster, 21 parts of coix seed, Radix Codonopsis 16 Part, 21 parts of Semen Lablab Album, 21 parts of Semen Cuscutae, 16 parts of mulberries, 11 parts of Chinese cassia tree, 31 parts of pawpaw, 11 parts of fructus amomi, 16 parts of teasel root, the fruit of Chinese wolfberry 16 parts, 11 parts of semen allii tuberosi, 11 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 13h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 5.5h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 45min, cross 80 mesh and sieve 3 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 5
A kind of drug for treating cardiac neurosis includes according to the raw material of parts by weight：12 parts of the root of bidentate achyranthes, 18 parts of psoralea corylifolia, life 32 parts of keel, 22 parts of Radix Paeoniae Alba, 18 parts of rhizoma atractylodis macrocephalae, 5.5 parts of campanulaceae, 18 parts of fructus alpiniae oxyphyllae, 22 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 32 parts of Herba Cistanches, thizoma curculiginis 5.5 parts, 22 parts of the seed of Oriental arborvitae, 5.5 parts of folium artemisiae argyi, 5.5 parts of Rhizoma Et Radix Notopterygii, 32 parts of ginger carbon, 18 parts of lotus seeds, 32 parts of Chinese yam, 32 parts of amethyst, toast 18 parts of Radix Glycyrrhizae, 18 parts of Poria cocos, 5.5 parts of donkey-hide gelatin, 5.5 parts of deer horn glue, 22 parts of Morinda officinalis, 18 parts of Herba Epimedii, 22 parts of Radix Angelicae Sinensis, dogwood fruit 22 parts, 5.5 parts of fennel seeds, 5.5 parts of ching-chieh, 100 parts of radix rehmanniae preparata, 32 parts of Gorgon fruit, 32 parts of raw oyster, 22 parts of coix seed, Radix Codonopsis 18 Part, 22 parts of Semen Lablab Album, 22 parts of Semen Cuscutae, 18 parts of mulberries, 12 parts of Chinese cassia tree, 32 parts of pawpaw, 12 parts of fructus amomi, 18 parts of teasel root, the fruit of Chinese wolfberry 18 parts, 12 parts of semen allii tuberosi, 12 parts of Rhizoma Chuanxiong.
The preparation method of the drug of the treatment cardiac neurosis, is as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 14h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 6h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 50min, cross 80 mesh and sieve 2 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
Implement case
1, case selection, patient age range, course of disease time
Guangxi University of Chinese Medicine's the first affiliated hospital Neurology and cardiology department out-patient 100 are chosen, is randomly divided into 2 Group.50 patients of herbal paste group of the present invention, wherein man 22, female 28；It is age 20-55 Sui, average（38.56±15.78）Year；Disease It is Cheng Sanyue -36 months, average（12.45±5.07）Month.50 patients of Western medicine group give metoprolol tartrate tablets+oryzanol tablets+fluorine piperazine Thioxanthene melitracen piece is treated, wherein man 27, female 23；It is age 18-55 Sui, average（37.08±14.98）Year；The course of disease 3 It is -35 months moons, average（11.45±4.25）Month.
2, diagnostic criteria brief introduction
Reference《Practical clinical practice》CN diagnostic criteria：（1）Symptom：There is palpitaition dynamic, precordialgia, front are felt oppressed, breathed It is unsmooth equal with typical vegetative nerve function adjusting disorder symptoms；（2）Sign：There is the positive sign of diagnostic value to lack It is weary；（3）Auxiliary examination：Normal ECG is substantially normal, the common tachycardia of electrocardiographic abnormality（Dou Xing）, the paroxysmal rhythm of the heart not Together（Dou Xing）Or it is accidental be mainly limited to II, III, the ST-T sections of av F leads change, propanolol test is positive, to suspecting device The case that matter venereal disease becomes shows that result is normal after the invasive diagnosis coronary artery revasualization of row.
3, curative effect determinate standard：
Reference《New Chinese medicine guideline of clinical investigations》The effect of evaluation criteria：It is calculated using Nimodipine method.Therapeutic index= （Prior treatment integral-post treatment integral）/ prior treatment integral × 100%.1. clinical recovery：Cardinal symptom, sign disappear or disappear substantially It loses, therapeutic index >=95%.2. effective：Cardinal symptom, sign are obviously improved, 70%≤therapeutic index<95%.3. effectively：Main disease Shape, sign are clearly better, 30%≤therapeutic index<70%.4. invalid：Cardinal symptom, sign are not improved, even aggravating, are treated Imitate index<30%.
4, drug application method
Herbal paste group：The treatment of present invention side is given, 2 times a day, each 20ML, warm water takes.
Western medicine group：It gives（1）Metoprolol tartrate, takes orally, 2 times/d 12.5 mg/ time；（2）Oryzanol tablets, 20 mg/ It is secondary, it takes orally, 3 times/d；（3）Flupentixol and Melitracen Tablets, every 10 mg containing 0.5 mg of Flupentixol and melitracen, often Early morning day, noon respectively take 1.
5, clinical treatment outcome is shown in Tables 1 and 2.
Table 1：Two groups of pretherapy and post-treatment cardinal symptom integral contrasts
Group n Before treatment After treatment Therapeutic index
Western medicine group 50 13.03±3.15 7.16±1.54*# 0.70±0.15#
Herbal paste group 50 13.10±3.09 4.59±1.28*# 0.81±0.20#
Note：Compared with Western medicine group：*P<0.05, #P<0.01.After treatment, herbal paste group of the present invention is obviously improved patient's cardinal symptom（P <0.05）, curative effect is more precisely（P<0.01）.
It is shown in Table 2：Curative effect compares after two groups of treatments
Group Number of cases Recovery from illness It is effective Effectively In vain Total effective rate
Western medicine group 50 5 10 20 15 70 %
Herbal paste group 50 18 22 7 3 94%
Note：Compared with Western medicine：*P<0.01.After treatment, it is effective compared with Western medicine group that herbal paste group of the present invention treats the disease（P<0.01）.
Clinical case is observed：
Case 1：×, man, 36 years old, people from Nanning, the course of disease 3 years, symptom discomfort uncomfortable in chest, squeezing sense, shortness of breath, palpitaition, with the heart It is tired easily nervous, it thinks much and worries too much, drink is received not good enough, and night sleeps dreaminess, and the whole body is weak.It breaks out on emotional stimulation, breaking-out is notably on the point of Dead sense.Dark tongue quality, tongue is thin, small and wiry pulse.Once repeatedly looked into electrocardiogram and heart color Doppler be showed no apparent positive findings, examine for " cardiac neurosis ".Oral " metoprolol tartrate " 12.5 mg p.o Bid do not improve through treating the half a year state of an illness； It is treated through drug of the present invention, symptom is relieved after treatment 30 days, and no recurrence was observed during the follow-up period of 6 months.
Case 2：Cao ×, female, 50 years old, people from Liuzhou, the course of disease 1 year, uncomfortable in chest, nervous, vexed out of breath, the abdominal distension of symptom interruption It is indigestion and loss of appetite, poor dreaminess of sleeping, dilute, oliguresis when stool is dry.Pale tongue lacks tongue, deep thready pulse.Local hospital outpatient service interruption is medical, perfect " cardiac neurosis " is diagnosed after coherence check, takes orally " metoprolol tartrate " 12.5 mg p.o Bid, when symptom has Alleviate.Dissatisfied therapeutic effect, it is then medical to our hospital, it is treated through drug of the present invention, symptom is relieved after treatment 2 weeks, follow-up 1 Year no relapse.
Case 3：It is yellow ×, man, 46 years old, people from Nanning, the course of disease 2 years, symptom palpitaition, when there is the bored pain in front, mesh to do swollen, mouth It is dry.The red few tongue of tongue, arteries and veins are thin.Electrocardiogram is repeatedly looked into through our hospital and heart color Doppler is showed no obvious abnormalities.Oral " tartaric acid 12.5 mg p.o Bid of metoprolol "；It is treated through drug of the present invention, symptom is relieved after treating January, and follow-up has no for 2 years Recurrence.
Case 4：Old ×, female, 50 years old, people from Guilin, 5-year courses, symptom was nervous, breaks out on emotional stimulation, sent out Notably there is dying sense.Hectic fever, xerophtalmia, the soreness of waist is soft, weak.Tongue is red, few tongue, deep thready pulse.Coronary angiography is looked into our hospital's outpatient service " having no organic disease " takes orally " metoprolol tartrate " 12.5 mg p.o Bid；There is alleviation when symptom, is unsatisfied with treatment Effect；It is treated through drug of the present invention, symptom is relieved after treatment 2 months, and no recurrence was observed during the follow-up period of 6 months.
Case 5：King ×, man, 49 years old, people from Nanning, course of disease June, symptom was uncomfortable in chest, palpitaition, coerced scorching hot, double knees soreness, Mesh is dry, dry.The red few tongue of tongue, arteries and veins are thin.In our hospital's outpatient service electrocardiogram and Color Sonography no abnormality seen.Oral " tartaric acid Mei Tuoluo You " 12.5 mg p.o Bid；It is treated through drug of the present invention, symptom is relieved after treatment 15 days, and no recurrence was observed during the follow-up period of 6 months.
Guiding fire to origin of the present invention, mental-tranquilization：Soup of igniting in side is main ingredient, the kidney being a ZANG-organ containing both water and fire.It is kidney yin, that is, Kidney-Yin, true Water；It is kidney yang, that is, Yuanyang, kidney-yang.Side is monarch with radix rehmanniae preparata, mends its kidney water greatly, water is prosperous to be enough fire processed.The temperature of Morinda offcinalis How is added again, then extreme misery Both helped, under water becomes, and the existing gesture therewith of having to of fire, more increasings Poria cocos it is leading, then extreme misery becomes together, and is satisfied with kidney palace altogether.Add The straight nourishing heart blood of donkey-hide gelatin, the seed of Oriental arborvitae, then coordination between the heart and kidney return member and open Thailand, not less than there is the harmony being on friendly terms.
Blood-nourishing tune liver, soothing the liver promoting the circulation of qi：Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong are Siwu Tang replenishing blood for nourishing heart, liver promoting the circulation of qi liver of relaxing.Invigorating the spleen benefit Gas, with angry blood：Poria cocos, rhizoma atractylodis macrocephalae, Radix Codonopsis strengthening the spleen and replenishing qi in side, the strong then qi and blood biochemistry of spleen is active, reaches and controls deficiency of heart-blood Purpose.
Mend nourishing liver and kidney：Fang Zhongjia Chinese yams, prepared rehmannia root, Fructus Corni, matrimony vine, mulberries nourish liver blood tranquilizing the mind, benefiting kidney-essence, cloudy Essence can prevent yang-energy superinverse completely.
Warm sun mends bank：Thizoma curculiginis, folium artemisiae argyi, Morinda officinalis, fennel seeds, Herba Epimedii, semen allii tuberosi Wen Yang are to open kidney water, the kidney Ji heart waterborne God and nourishing heart.
Beneficial to spirit and marrow：Herba Cistanches, teasel root, wine yellow rice wine, Semen Cuscutae, psoralea corylifolia, fructus alpiniae oxyphyllae beneficial to spirit and marrow.
It replenishes qi to invigorate the spleen, emergency：Honey-fried licorice root is longer than middle benefit gas, and with sweet temperature QI invigorating, relieving spasm to stop pain power is strong.
Invigorating the spleen for eliminating dampness, promoting the circulation of qi are led stagnant：It is largely tonic in side, easily hinders taste, adds coix seed, fructus amomi, Rhizoma Et Radix Notopterygii, white Hyacinth bean, schizonepeta, campanulaceae, pawpaw, ginger carbon promoting the circulation of qi are led stagnant, make benefit without stagnant, are grown and oiliness.
The present invention has orderly and clearly feelings will, invigorating the spleen and stomach to CN patient, restoring normal coordination between heart and kidney and improve vegetative dystonia and reach The effect of antitoxic heart-soothing and sedative can also be adjusted internal organs negative and positive of qi and blood, and reach the adjustment to constitution by invigorating heart and kidney, from basic Upper treatment disease.By largely using present invention side, it is found that the clinical efficacy for the treatment of CN is better than Western medicine, in treatment palpitaition main symptom Meanwhile other accompanying symptoms are also effectively improved, and are such as felt depressed, chest expires bored, distending pain in the chest and hypochondrium, or irritability discomfort etc. of easily crying.It Have：1, treating both manifestation and root cause of disease.It breaks through western medical treatment limitation, and advantage of the succession Traditional Chinese Medicine Chinese medicine in treating disease is being treated While disease, each internal organs qi and blood, negative and positive can be adjusted, body is made to be in equilibrium state；2, other accompanying symptoms improve, through the invention Side adjusts the biased of viscera, other minor symptoms are also effectively relieved；3, from doctor trained in Western medicine angle, there are orderly and clearly feelings in the party Will, invigorating the spleen and stomach, restoring normal coordination between heart and kidney and improve vegetative dystonia and have the function that antitoxic heart-soothing and sedative.4, effect mitigates lasting, The invention is started with from the essence for the treatment of disease, is improved at all, and effect will be permanent uneasy to recur, makes up western medical treatment not Foot；5, patient compliance is good, and instructions of taking is simple, in good taste, significant in efficacy, and patient is easily accepted by.The 3-4 course for the treatment of is taken, tune is reached The rhythm of the heart is saved, mass action of making the life better can be with across-the-board regulation constitution.
The present invention expands Chinese medical culture product treatment Common neurologic disease by treating CN with present invention side Range does not only reach good therapeutic effect, and can be adjusted according to the biased of constitution, elimnation for excess and tonification for deficiency, mends without stagnant, tune Whole energy and blood of human body, negative and positive make human body be in equilibrium state, raise internal organs, defend tenaciously nephroyin and nephroyang originally.It is controlled by this method It treats, the clinical symptoms of CN can not only be alleviated, also fundamentally solve the problems, such as that treatment is easily recurred, achieve the purpose that search for the primary cause of disease in treatment. Present invention effect is significantly, few side effects, patient compliance are good, it is convenient, in good taste to carry storage, for the development of current Chinese medicine modernization Pattern meets social development needs.It is a further object of the present invention to provide the production methods of the drug, and medicinal material is added water to cook, It removes slag, after concentration, adds stiff semiliquid preparations made of honey, specification and guidance are provided for the making of herbal paste.The main needle of the present invention Treatment to CN, due to the correlation of constitution, the starting point for the treatment of is started with from constitution, be can be used for treating neurosis, is slept The nervous system diseases such as dormancy obstacle, depressive disorder；The digestion such as refractory gastroesophageal reflux disease, rectal prolapse, gastroptosis, functional abdominal pain Systemic disease；The andrological diseases such as seminal emission, impotence, premature ejaculation, infertility；The gynecological diseases such as metroptosis, infertile；Glaucoma, cataract, The ophthalmology diseases such as muscae volitantes；And the diseases such as chronic eczema, alopecia, degenerative arthritis, protrasion of the lumbar intervertebral disci.
It is compared with conventional medicine, the unique distinction of side of the present invention is shown：1, it is used for cardiac neurosis and embodies Chinese medicine The characteristics for the treatment of based on disease differentiation diagnosis and treatment disease；Human body is adjusted comprehensively with numerous medicines, embodies the overall situation thought of Chinese medicine Overall View.2, originally The numerous drug interactions of invented party take orally rear rapid decomposition absorption after cream is made, play orderly and clearly feelings will, invigorating the spleen and stomach, traffic Heart kidney and improve vegetative dystonia and have the function that antitoxic heart-soothing and sedative.The pathogenesis for fundamentally solving CN, reaches and controls Therapeutic effect.3, the feature based on present invention side is easy to be accepted by patients, and has good clinical efficacy and wide social demand, It is worth clinical expansion and uses.4, it finding to treat by the medicine by a large amount of clinical observation, high efficiency is uneasy to recur, from The drawbacks of fundamentally easily being recurred after solution nervous system disease.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective Various changes can be made.

Claims (4)

1. a kind of drug for treating cardiac neurosis, which is characterized in that include according to the raw material of parts by weight：Root of bidentate achyranthes 8-12 Part, 12-18 parts of psoralea corylifolia, 28-32 parts of Os Draconis, 18-22 parts of Radix Paeoniae Alba, 12-18 parts of rhizoma atractylodis macrocephalae, 4.5-5.5 parts of campanulaceae, fructus alpiniae oxyphyllae 12-18 parts, 18-22 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 28-32 parts of Herba Cistanches, 4.5-5.5 parts of thizoma curculiginis, 18-22 parts of the seed of Oriental arborvitae, folium artemisiae argyi 4.5-5.5 Part, 4.5-5.5 parts of Rhizoma Et Radix Notopterygii, 28-32 parts of ginger carbon, 12-18 parts of lotus seeds, 28-32 parts of Chinese yam, 28-32 parts of amethyst, honey-fried licorice root 12- 18 parts, 12-18 parts of Poria cocos, 4.5-5.5 parts of donkey-hide gelatin, 4.5-5.5 parts of deer horn glue, 18-22 parts of Morinda officinalis, 12-18 parts of Herba Epimedii, when Return 18-22 parts, 18-22 parts of dogwood fruit, 4.5-5.5 parts of fennel seeds, 4.5-5.5 parts of ching-chieh, 80-100 parts of radix rehmanniae preparata, Gorgon fruit 28- 32 parts, 28-32 parts of raw oyster, 18-22 parts of coix seed, 12-18 parts of Radix Codonopsis, 18-22 parts of Semen Lablab Album, 18-22 parts of Semen Cuscutae, mulberries 12-18 parts, 8-12 parts of Chinese cassia tree, 28-32 parts of pawpaw, 8-12 parts of fructus amomi, 12-18 parts of teasel root, 12-18 parts of the fruit of Chinese wolfberry, semen allii tuberosi 8- 12 parts, 8-12 parts of Rhizoma Chuanxiong.
2. the drug for the treatment of cardiac neurosis according to claim 1, which is characterized in that according to the raw material of parts by weight Including：9-11 parts of the root of bidentate achyranthes, 14-16 parts of psoralea corylifolia, 29-31 parts of Os Draconis, 19-21 parts of Radix Paeoniae Alba, 14-16 parts of rhizoma atractylodis macrocephalae, campanulaceae 4.8-5.2 parts, 14-16 parts of fructus alpiniae oxyphyllae, 19-21 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 29-31 parts of Herba Cistanches, 4.8-5.2 parts of thizoma curculiginis, seed of Oriental arborvitae 19-21 Part, 4.8-5.2 parts of folium artemisiae argyi, 4.8-5.2 parts of Rhizoma Et Radix Notopterygii, 29-31 parts of ginger carbon, 14-16 parts of lotus seeds, 29-31 parts of Chinese yam, amethyst 29- 31 parts, it is 14-16 parts of honey-fried licorice root, 14-16 parts of Poria cocos, 4.8-5.2 parts of donkey-hide gelatin, 4.8-5.2 parts of deer horn glue, 19-21 parts of Morinda officinalis, excessive 14-16 parts of the sheep leaves of pulse plants, 19-21 parts of Radix Angelicae Sinensis, 19-21 parts of dogwood fruit, 4.8-5.2 parts of fennel seeds, 4.8-5.2 parts of ching-chieh, radix rehmanniae preparata 85- 95 parts, 29-31 parts of Gorgon fruit, 29-31 parts of raw oyster, 19-21 parts of coix seed, 14-16 parts of Radix Codonopsis, 19-21 parts of Semen Lablab Album, Semen Cuscutae 19-21 parts, 14-16 parts of mulberries, 9-11 parts of Chinese cassia tree, 29-31 parts of pawpaw, 9-11 parts of fructus amomi, 14-16 parts of teasel root, fruit of Chinese wolfberry 14-16 Part, 9-11 parts of semen allii tuberosi, 9-11 parts of Rhizoma Chuanxiong.
3. the drug for the treatment of cardiac neurosis according to claim 1, which is characterized in that according to the raw material of parts by weight Including：10 parts of the root of bidentate achyranthes, 15 parts of psoralea corylifolia, 30 parts of Os Draconis, 20 parts of Radix Paeoniae Alba, 15 parts of rhizoma atractylodis macrocephalae, 5 parts of campanulaceae, 15 parts of fructus alpiniae oxyphyllae, wine 20 parts of sealwort, 30 parts of Herba Cistanches, 5 parts of thizoma curculiginis, 20 parts of the seed of Oriental arborvitae, 5 parts of folium artemisiae argyi, 5 parts of Rhizoma Et Radix Notopterygii, 30 parts of ginger carbon, 15 parts of lotus seeds, Chinese yam 30 parts, 30 parts of amethyst, 15 parts of honey-fried licorice root, 15 parts of Poria cocos, 5 parts of donkey-hide gelatin, 5 parts of deer horn glue, 20 parts of Morinda officinalis, 15 parts of Herba Epimedii, 20 parts of Radix Angelicae Sinensis, 20 parts of dogwood fruit, 5 parts of fennel seeds, 5 parts of ching-chieh, 90 parts of radix rehmanniae preparata, 30 parts of Gorgon fruit, 30 parts of raw oyster, coix seed 20 Part, 15 parts of Radix Codonopsis, 20 parts of Semen Lablab Album, 20 parts of Semen Cuscutae, 15 parts of mulberries, 10 parts of Chinese cassia tree, 30 parts of pawpaw, 10 parts of fructus amomi, teasel root 15 Part, 15 parts of the fruit of Chinese wolfberry, 10 parts of semen allii tuberosi, 10 parts of Rhizoma Chuanxiong.
4. a kind of preparation method of the drug for the treatment of cardiac neurosis as described in any one of claims 1-3, feature exist In being as follows：
（1）Each raw material is weighed according to parts by weight, and by the root of bidentate achyranthes, psoralea corylifolia, Os Draconis, Radix Paeoniae Alba, rhizoma atractylodis macrocephalae, campanulaceae, fructus alpiniae oxyphyllae, wine It is sealwort, Herba Cistanches, thizoma curculiginis, the seed of Oriental arborvitae, folium artemisiae argyi, Rhizoma Et Radix Notopterygii, ginger carbon, lotus seeds, Chinese yam, amethyst, honey-fried licorice root, Poria cocos, Morinda officinalis, excessive The sheep leaves of pulse plants, Radix Angelicae Sinensis, dogwood fruit, fennel seeds, radix rehmanniae preparata, Gorgon fruit, raw oyster, coix seed, Radix Codonopsis, Semen Lablab Album, Semen Cuscutae, mulberries, pawpaw, Teasel root, the fruit of Chinese wolfberry, semen allii tuberosi, Rhizoma Chuanxiong impregnate 10-14h with water immersion；
（2）The drug of above-mentioned immersion is added in Chinese medicine machine and decocts 4-6h, removal surfactant foam is stirred while decocting；
（3）Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained；
（4）So that it is dissolved the heating of deer horn glue, donkey-hide gelatin and Chinese cassia tree, adds into above-mentioned concentrated medicament, ching-chieh, sand is added Benevolence, slow boiling heat 30-50min, cross 80 mesh and sieve 2-3 times, then small fire boils paste；
（5）Honey receipts cream is added and is fabricated to herbal paste to obtain the final product.
CN201810711319.3A 2018-07-03 2018-07-03 A kind of drug and preparation method thereof for treating cardiac neurosis Pending CN108514631A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110151887A (en) * 2019-06-26 2019-08-23 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine composition promoting human qi and blood running

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101095886A (en) * 2007-06-29 2008-01-02 战树森 Chinese traditional medicine for treating heart neurosis and method for preparing the same
CN102961621A (en) * 2012-11-09 2013-03-13 成都绿迪科技有限公司 Traditional Chinese medicine preparation for treating viral cardiac neurosis
CN103610870A (en) * 2013-12-12 2014-03-05 侯书圣 Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
CN105641526A (en) * 2016-02-02 2016-06-08 刘云杰 Traditional Chinese medicine for treating cardiac neurosis
CN107303383A (en) * 2016-04-21 2017-10-31 张东 A kind of Chinese medicine composition and its derivative and product to a variety of symptoms with effect
CN107375574A (en) * 2017-07-24 2017-11-24 黑龙江神志医院有限公司 A kind of Chinese medicine composition for treating cardiac neurosis and its application

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101095886A (en) * 2007-06-29 2008-01-02 战树森 Chinese traditional medicine for treating heart neurosis and method for preparing the same
CN102961621A (en) * 2012-11-09 2013-03-13 成都绿迪科技有限公司 Traditional Chinese medicine preparation for treating viral cardiac neurosis
CN103610870A (en) * 2013-12-12 2014-03-05 侯书圣 Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
CN105641526A (en) * 2016-02-02 2016-06-08 刘云杰 Traditional Chinese medicine for treating cardiac neurosis
CN107303383A (en) * 2016-04-21 2017-10-31 张东 A kind of Chinese medicine composition and its derivative and product to a variety of symptoms with effect
CN107375574A (en) * 2017-07-24 2017-11-24 黑龙江神志医院有限公司 A kind of Chinese medicine composition for treating cardiac neurosis and its application

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
王一东等: "中医辨证论治心脏神经官能症54例", 《中医临床研究》 *
范宏涛等: "归脾汤加减治疗心脏神经官能症69例观察", 《云南中医学院学报》 *
贺君等: "中医药治疗心血管神经官能症效果探析", 《中外医疗》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110151887A (en) * 2019-06-26 2019-08-23 眉山市中医医院(眉山市东坡区人民医院) A kind of Chinese medicine composition promoting human qi and blood running

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Application publication date: 20180911