CN103356970A - Traditional Chinese medicine composition for treating mammary gland hyperplasia - Google Patents

Abstract

The invention provides a traditional Chinese medicine composition for treating mammary gland hyperplasia. The traditional Chinese medicine composition comprises natural Chinese herbal medicines such as charred triplet, chicken's gizzard membrane, ligusticum wallichii, red sage root, radix scrophulariae, curcuma tuber, gleditsia sinensis, Radix Codonopsis, bighead atractylodes rhizome, radix bupleuri, balloonflower root, isatis root, desmodium, banksia rose, radix paeoniae rubrathe, oyster, trichosanthes root, magnolia cortex, poria cocos, root of kudzu vine, root of large-flowered skullcap, semen cuscutae, and dandelion as active drugs. Through active ingredient extraction, the traditional Chinese medicine composition has effects of soothing liver and regulating qi, promoting blood circulation to arrest pain, resolving hard lump and eliminating phlegm and freeing channels and can treat various mammary gland hyperplasia.

Description

A kind of Chinese prescription for the treatment of cyclomastopathy

Technical field

The invention belongs to tcm field, relate to a kind of Chinese prescription for the treatment of cyclomastopathy.

Background technology

Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.Should be the trend that rises year by year by the disease sickness rate in the last few years, the age also more and more becomes younger.Cyclomastopathy is normal breast lobule physiological hypertrophy and subinvolution, and the mammary gland normal configuration gets muddled, and belongs to pathological proliferation.It is neither inflammation a class of non-tumor is sick again, be mainly in 30-50 year women, onset peak is 35-40 year.At present the real pathogenic factor of this disease is also indefinite, thinks relevant with endocrine disturbance and spirit, environmental factors etc. more.

Chinese medicine is recited as within " nodules of the breast " category, thinks by internal damage by the excessive seven emotions, and mental pressure is excessive, the change of life style, so that depression of liver-QI, stagnation of QI expectorant is solidifying, pent-up.Pathologic cyclomastopathy needs active treatment, especially cystic hyperplasia type, owing to there is the possibility of canceration, can not adopt a casual attitude.If the generation canceration, the excision normal organ causes psychic trauma irretrievable and that can't remedy for patient, family, has produced huge stress.

Treat clinically cyclomastopathy, medicine majority commonly used is Chinese patent medicine, has the effects such as blood circulation promoting and blood stasis dispelling, depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, compensate qi and blood, owing to select medical material different, disease is different, and therapeutic effect differs greatly.In addition, hormonotherapy is arranged still, the someone adopts the androgen in treating primary disease, but that this treatment might aggravate between the human hormone is unbalance, unsuitable conventional the application.Only at serious symptom, when impact normal operation and life, just consider to adopt.

Chinese prescription of the present invention is controlled analysis according to debating of " nodules of the breast " because more, the common curing mammary gland hyperplasia medicine of sick type of cyclomastopathy needs clearly for sick type, therefore for diagnosis require highly, mistaken diagnosis also is clinical common situations.The present invention has overcome the weakness of general pharmaceutical preparation, combines the quality of various medicines, has taken into full account the property of medicine and the coordination habit of selecting medicine.Finally select medicine with depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, hard masses softening and resolving, eleminating phlegm and freeing channels is main, and is all effective in cure to various sick suppurative mastitis gland hypertrophy, and treatment means allows the patient establish and defeats ailing firming confidence, and wholwe-hearted partner treatment can reach satisfied effect.

Technology contents

The purpose of this invention is to provide a kind of Chinese prescription for the treatment of cyclomastopathy, this Chinese prescription selects natural Chinese medicinal herb as active medical material, has preferably therapeutic effect.

The Chinese prescription that the present invention treats cyclomastopathy is comprised of following each Chinese medicine ingredients:

JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Endothelium Corneum Gigeriae Galli, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Scrophulariae, Radix Curcumae, Spina Gleditsiae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Radix Platycodonis, Radix Isatidis, Herba Lysimachiae, the Radix Aucklandiae, Radix Paeoniae Rubra, Concha Ostreae, Radix Trichosanthis, Cortex Magnoliae Officinalis, Poria, Radix Puerariae, Radix Scutellariae, Semen Cuscutae, Herba Taraxaci.

The present invention has the medicated wine of promoting blood circulation and stopping pain resist inflammation on repercussive function, and the pharmacology attribute of each medical material is as follows:

JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata): namely Fructus Hordei Germinatus (parched to brown), Fructus Crataegi (parched to brown), this three flavor of Massa Medicata Fermentata (parched to brown) often share being collectively referred to as of the stagnant Chinese medicine that acts on of good removing food stagnancyization.This three flavors medicine has all that good removing food stagnancyization stagnates, the function of resolving depression eliminating stagnation.

Fructus Hordei Germinatus (parched to brown) has invigorating the spleen and regulating the stomach, the stagnant merit of soothing liver-QIization, is used for the treatment of that food stagnation does not disappear, the disease such as distension and fullness in the abdomen, inappetence, vomiting are had loose bowels.Modern study thinks that rich in starch catabolic enzyme, conversion carbohydrase, esterified enzyme, vitamin B etc. have good digestion-aid effect in the Fructus Hordei Germinatus.

Fructus Crataegi (parched to brown) has the slow and lasting effect that reduces blood pressure, but also cholesterol reducing and triglyceride, atherosclerosis, but but also the diastole coronary artery increases myocardial contraction, to arrhythmia.Therefore, be conducive to prevent and treat hypertension, hyperlipidemia, arteriosclerosis and coronary heart disease.

Massa Medicata Fermentata (parched to brown) has the digestant effect of strengthening the spleen and stomach, therefore, for bad, the feeling of stuffiness in chest abdominal distention of the digestion due to the diet internal injury effect is arranged quite.

Endothelium Corneum Gigeriae Galli, sweet in the mouth, cold in nature.Return spleen, stomach, small intestinal, urinary bladder channel.It is aid digestion to have promoting digestion and invigorating the stomach, the arresting seminal emission function.Endothelium Corneum Gigeriae Galli uses in multiple cyclomastopathy prescription, and the effect research of live chickens Endothelium corneum in experimental cyclomastopathy treatment has been studied the associating Traditional Chinese Medicine Research Institute, Jiangxi Province by Jiangxi Province chest hospital, confirms that Endothelium Corneum Gigeriae Galli is effective for the treatment cyclomastopathy.

Rhizoma Chuanxiong, acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Effect classification: qi-activating drug; Medicine dispels the wind; The blood circulation promoting medicine blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Cure mainly: women's stasis of blood in puerperal stagnates raw meat bitterly, the lump in the abdomen lump, and pain in chest and hypochondrium, it is dizzy to have a headache, cold-damp numbness; Ulcer sores.

Radix Salviae Miltiorrhizae, bitter in the mouth, cold nature.Be included into the heart, Liver Channel.Have promoting blood circulation to remove blood stasis, detumescence hemostasis, anti-inflammatory analgetic, menstruction regulating and pain relieving, coronary artery dilator, improve the myocardial ischemia situation, with all worries set aside, blood sugar lowering and the effect such as antibiotic reduce blood pressure, calm the nerves, to menoxenia, the amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris have certain curative effect.

Radix Scrophulariae, sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.Has clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing function.Be usually used in pathogenic warmth and join the army, the pericardium that caves in, maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin.

Radix Curcumae, acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.Effect is promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine.

Spina Gleditsiae, acrid in the mouth, warm in nature.Return liver, stomach warp, the evacuation of pus of drawing out pus by applying a plaster to the affected part, promoting blood circulation and detumescence.Be used for carbuncle, sore, pus do not become to burst scabies.Usual amounts 5～10 grams, suitable amount used externally, vinegar are fried in shallow oil and are coated with the affected part.

Radix Codonopsis has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis contain various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, have enhancing immunity, blood vessel dilating, blood pressure lowering, improve microcirculation, strengthen the effects such as hemopoietic function.The leukopenia that in addition chemotherapy radiotherapy is caused has castering action.

The Rhizoma Atractylodis Macrocephalae, bitter in the mouth; Sweet; Warm in nature.Return spleen, stomach warp.Have invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, the dampness diuretic reduces phlegm, and hidroschesis is antiabortive, increases the appetite effect.

Radix Bupleuri, function: 1. treating SHAO YANG disease by mediation: be used for fever caused by exogenous pathogens, or the evil alternate attack of chill and fever that enters half exterior and half interior and malaria cold and heat etc., such as (＜Treatise on Febrile Diseases〉Herba Sidae Rhombifoliae soup), (decoction for dispelling pathogens from superficial muscles).2. dispersing the stagnated live-QI to relieve the stagnation of QI: be used for stagnation of QI due to depression of the liver, side of body rib distension pain, and hepatic depression and blood deficiency, menoxenia etc., as (＜Jing Yue's complete work〉bupleurum powder for relieving liver-qi).

Radix Platycodonis, bitter in the mouth, suffering, property is flat.Return lung meridian.Lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.Be used for cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, uroschesis.Be used for cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.

Radix Isatidis, heat and toxic materials clearing away medicine, blood-cooling drugs.Bitter in the mouth, cold in nature.1. " book on Chinese herbal medicine is just read ": enter liver, stomach blood system.2. " China's book on Chinese herbal medicine ": return liver; The stomach warp.Effect is heat clearing away, detoxifcation, removing heat from blood, sore-throat relieving.Be used for maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis.

Herba Lysimachiae, sweet in the mouth, little hardship, cool in nature.Return liver, gallbladder, kidney, urinary bladder channel.Effect, relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Cure mainly liver and gall and urinary system calculus; Pyretic stranguria; Oedema due to nephritis; Jaundice due to damp-heat; The sore carbuncle; Venom; Traumatic injury.

The Radix Aucklandiae, acrid in the mouth; Bitter; Warm in nature.1. " herbal classic ": acrid in the mouth, temperature.2. Materia Medica of Decoction: gas heat, acrid in the mouth is bitter, and is nontoxic.Return spleen, large intestine, tri-jiao channel.Be used for promoting the circulation of QI to relieve pain; Intestinal stasis relieving in the accent.Main born of the same parents coerce the distension foot; Abdominal distention; Tell and have loose bowels; Heavy after the dysentery.Be used for heavy behind breast gastral cavity distending pain, the dysentery, food stagnation does not disappear, anorexia.

Radix Paeoniae Rubra, bitter in the mouth, cold nature.Return Liver Channel.Be used for clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Main maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, carbuncle skin infection.

Concha Ostreae, salty in the mouth, cold nature; Return liver, gallbladder, kidney channel.Function: medicine for calming liver and calming endopathic wind; Yin-nourishing drug.Be used for vertigo and tinnitus, scrofula goiter, lump in the abdomen mass in the abdomen.

Radix Trichosanthis, sweet in the mouth, little hardship, cold nature.Attach to the lung and stomach meridians.Effect: clearing away heat and promoting production of body fluid, detumescence and apocenosis.Be used for the calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.

Cortex Magnoliae Officinalis, bitter in the mouth, suffering; Warm in nature.Return spleen, stomach warp, large intestine channel.Has the circulation of qi promoting removing food stagnancy; Dampness is except full; The lowering the adverse QI to relieve asthma effect.Be used for stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough.

Poria: sweet in the mouth, light, property is flat.GUIXIN warp, lung meridian, spleen channel, kidney channel.Function: diuretic medicine; Diuretics with the action of eliminating dampness.Be used for dysuria, edema distension, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.

Radix Puerariae, sweet in the mouth, suffering, property is flat.Be included into spleen, stomach warp.Have the yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness ends warm effect.Cold, the warm headache stiffness of the nape that cures the wound, dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, and dysentery, skin eruption are not saturating, hypertension, angina pectoris, deafness.

Radix Scutellariae, bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Effect is heat clearing and damp drying, eliminating fire and detoxication, and hemostasis, antiabortive, blood pressure lowering.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus.

Semen Cuscutae, acrid in the mouth, sweet, slightly warm in nature; Return the liver,kidney,spleen warp; Gas and property are slow, can float and can sink.Has the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, the solid tire of spleen invigorating.Cure mainly lumbago tinnitus, impotence and seminal emission is quenched one's thirst, and is sterile, enuresis incontinence, and the stranguria with turbid discharge leukorrhagia, the head is dim, and lack of appetite is had loose bowels.

Herba Taraxaci, sweet in the mouth, little hardship, cold in nature.Heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation.Be included into spleen, stomach, kidney three warps.Be used for upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, the various inflammation such as acute appendicitis.

Chinese prescription of the present invention is selected medical material, effect: depressed liver-energy dispersing and QI regulating (Herba Lysimachiae, Radix Paeoniae Rubra, Concha Ostreae, Semen Cuscutae), promoting blood circulation and stopping pain (Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Curcumae, Spina Gleditsiae), hard masses softening and resolving (JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Spina Gleditsiae, Radix Platycodonis, the Radix Aucklandiae), heat-clearing and toxic substances removing (Radix Scrophulariae, Radix Bupleuri, Radix Isatidis, Radix Platycodonis, Radix Trichosanthis, Radix Puerariae, Herba Taraxaci), eleminating phlegm and freeing channels (Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Platycodonis, Cortex Magnoliae Officinalis, Poria, Radix Scutellariae).

Chinese prescription of the present invention is not that simple effect is cumulative, has sufficient pharmacology's compatibility basis and actual clinical medication experience, forms the clinical proved recipe with definite effect.

The present invention treats the Chinese prescription of cyclomastopathy, and advantage is: 1, the treatment window is wide, regulates by system, for various cyclomastopathy better effects is arranged all.2, for the comparatively serious cyclomastopathy of morbidity, the general therapeutic effect is more obvious.But not yet confirming has clear and definite therapeutic effect for breast carcinoma.Because of clinical cost issues, do not make a search.

The Chinese prescription for the treatment of cyclomastopathy of the present invention can be made as required different dosage forms and use, and secondly administering mode preferred oral preparation is local administration preparation such as ointment, patch, spray etc.

The present invention treats the Chinese prescription of cyclomastopathy, has fast treating, the advantage that has no side effect.

Main reference document: [1] Ye Meina. the overview of Treatment of Mammary Hyperplasia by Ancient Formulae [J]. journal of shanghai Chinese medicine, 2004,38 (7): 62.[2] Li Huarong, Gao Fengxi. the literature review for the treatment of by Chinese herbs cyclomastopathy [J]. Chinese pharmacists, 2006,9 (1): 65.[3] Li Shumin, the stone Hefeng. Chinese Medicine treatment cyclomastopathy experimentation recent developments [J]. Chinese research, 2004,17 (4): 59.[4] Hu Jiwei, Li Jingwu. the clinical observation [J] of Radix Bupleuri is soothing the liver mixture treatment cyclomastopathy. Chinese medicine, 2008,46 (28): 71.[5] Tang Yuling. detumescence side's treatment cyclomastopathy 102 examples [J]. practical Chinese medicine magazine, 2004,20 (2): 72.[6] Cui Lili, Dong Yanmei, Zhao Qingyu. the sick 88 routine clinical experiences [J] of Guizhi Fuling capsule on cyclomastopathy. the practical medicine of China, 2008,3 (26): 51.[7] Wang Guixiang. XIAOBI KOUFUYE treatment cyclomastopathy 53 examples [J]. Acupuncture Clinical, 2002,23 (11): 985.[8] Li Lin, Mu Yanyun. every Radix Aucklandiae cake treated with moxibustion cyclomastopathy clinical observation on the therapeutic effect [J] also. Chinese Pharmaceutical, 2006,22 (6): 35.[9] execute flat. compound Salviae Miltiorrhizae soup is on the impact [J] of cyclomastopathy rat hormonal readiness. the Hubei Journal of Traditional Chinese Medicine, 2008,30 (2): 14.[10] Bai Xuezhang, Bai Hua. hypertrophy soup treatment cyclomastopathy 31 examples [J]. the Shaanxi traditional Chinese medical science, 2008,29 (4): 459.[11] Lin Yi, Si Tuhonglin, Chen Qianjun. cyclomastopathy and Cycle therapy with Chinese traditional medicine [J]. Chinese medicine information, 2003,20 (1): 7.[12] Wang Huiping, Lou Lihua. cyclomastopathy experience [J] is treated with cream side by Lou Li CPTF. Zhejiang combination of Chinese and Western medicine magazine, 2009,19 (6): 355.[13] Wu Huaiyu. plus-minus decoction for removing blood stasis treatment cyclomastopathy 105 examples [J]. the Henan pharmaceutical information, 2001,9 (17): 37.[14] Jiang Rongchao. combination of Taohong Siwu decoction [J]. Liaoning Journal of Traditional Chinese Medicine, 2001,28 (6): 354.[15] Zhang Yan, Cui Zhiran. Fuyuan Huoxue Tang adds flavor treatment cyclomastopathy 80 examples [J]. the Shaanxi traditional Chinese medical science, 1994,15 (2): 52.[16] Wang Huliang. Fuyuan Huoxue Tang plus-minus treatment cyclomastopathy 53 routine observation of curative effect [J]. Zhejiang clinical medicine, 2001,3 (12): 900.[17] thin celebrating. add flavor Huoluo Xiaoling Dan treatment Mammary Hyperplasia in 38 Cases [J]. theory of medicine and practice, 1993,6 (1): 36.

Animal pharmacological experiment

1 materials and methods

1.1 material

1.1.1 medicine and reagent Experimental agents are by the present invention's development; Estradiol benzoate injection, Tianjin gold credit aminoacid company limited, 110217; Progesterone injection, Shanghai General Pharmaceutical Co., ltd., 100923; Special jasmine is fragrant, Rottendorf Pharma GmbH company, 100725.

1.1.2 animal, the SD rat, 60, female, body weight 180～220g is provided by Changsha medical experiment animal center.

1.1.3 instrument, slide gauge, chi industry company limited circles in the air in the Hunan; Electronic balance, Beijing Ka Er multiple instruments company limited.

1.2 method is got 60 of the female not pregnant rats of SD, is divided at random 3 groups, is respectively the blank group, Experimental agents group and reference medicine group.Except the blank group, all the other respectively organize rat by 0.5g/kg subcutaneous injection estradiol benzoate, and 1 time/d, in continuous 3 weeks, subcutaneous injection Progesterone 5mg/kg 1 time/d, injected for 1 week continuously subsequently.Blank group subcutaneous injection every day normal saline 0.2ml/ only injected for 4 weeks continuously.Each administration group is gastric infusion according to dosage, and sky is from matched group and give the equal-volume distilled water, and 1 time/d, continuous 8 weeks.1h after the last administration, rat anesthesia, abdominal vein get blood 3ml and make estradiol, progesterone, testosterone mensuration; Measure every rat chest the 2nd, 3 pairs of papilla of breast height with precision vernier callipers; Take off the 2nd pair of complete breast, scales/electronic balance weighing with the 8mm card punch.

2 results

2.1 Experimental agents of the present invention is on the impact of cyclomastopathy rat height of nipples.

Table 1 Experimental agents is on the impact of cyclomastopathy rat height of nipples

By as seen from Table 1 upper, experimental group is by after 8 weeks of medication, and rat the 2nd, 3 pairs of height of nipples are compared all with the blank group and obviously reduced (P＜0.01).

Table 2 Experimental agents is on the impact of cyclomastopathy rat breast weight

By as seen from Table 2 upper, can significantly reduce second pair of breast wt of cyclomastopathy rat in 8 weeks of trial drug medication.And effect is better than reference medicine group.

Clinical efficacy

1. sample information

The treatment case is female mammary gland proliferation patient patient.Age reckling 30 years old, the oldest person 59 years old.The patient is most by examination in hospital, is diagnosed as the cyclomastopathy symptom.

2. Therapeutic Method

Select Chinese medicine of the present invention, after the allotment, decoct with water 40 minutes in marmite in proportion, cooling is drunk, and once a day, whenever taking medicine decocts 2 times.6 days courses for the treatment of.

3. therapeutic outcome

53 examples, through 2～6 course of therapy, 25 examples of fully recovering, produce effects 13 examples, effective 12 examples, invalid 3 examples, total effective rate 94.3%.General one the course for the treatment of internal energy solution pain problem, eliminating hypertrophy fully need to be according to the order of severity of hypertrophy, for the hypertrophy symptom of early discovery, just can solve general 3～5 courses for the treatment of.Indivedual cyclomastopathy severe patients need prevention and the treatment of longer time.

4. model case

(1), Lee: woman, 37 years old, Wafangdian township, Dalian, Liaoning Province great virtue village people from village is engaged in building materials commerce, suffered from cyclomastopathy 6 years, taken medicine the time in 3 years in local people hospital, do not feel any better always, after taking this prescription, the symptom that lump in breast swells and ache takes a turn for the better gradually, took again four courses for the treatment of in inferior month after, the lump complete obiteration, not recurrence of return visit in 3 years.

(2), Liu, the woman, 48 years old, people from Hunan did manual work in the Dalian, gave birth to child after, stayed puerperal fever and cyclomastopathy in puerperal, after Dalian Affiliated Hospital is medical, do not feel any better, bad during state of an illness fashion, be in and can not dry weight live.Come here medical, take this 4th course for the treatment of of filling a prescription after, the lump in breast symptom all disappears.

(3), field, the woman, 31 years old, people from Hua County, Shaanxi, transfer three-family village, township, Wafangdian, Dalian, health is always good, when health check-up is participated in factory's working, finds that breast has lump, hospital doctor says early discovery, take medicine and just can disappear down, can take medicine the trimestral time in hospital still has lump, and symptom is more serious.Introduce here through relative, take this prescription after two courses for the treatment of, lump has disappeared.

(4), Zhang Yan, woman, 42 years old, Wafangdian, Dalian village people, the family financial situation difficulty is done manual work at Dongguan, Guangdong, felt uncomfortable in 2004, color ultrasound examination is done by hospital to the Dongguan, finds that breast has lump, in hospitalize after 6 months, effect is not very good, introduces here treatment through friend, takes this prescription after three courses for the treatment of, the state of an illness takes a turn for the better gradually, transference cure.

Specific embodiment

The various cleaning with Chinese herbal of selecting are clean, oven dry.Take by weighing each 25g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Endothelium Corneum Gigeriae Galli 18g, Rhizoma Chuanxiong 22g, Radix Salviae Miltiorrhizae 15g, Radix Scrophulariae 9g, Radix Curcumae 5g, Spina Gleditsiae 8g, Radix Codonopsis 11g, Rhizoma Atractylodis Macrocephalae 6g, Radix Bupleuri 12g, Radix Platycodonis 21g, Radix Isatidis 15g, Herba Lysimachiae 7g, Radix Aucklandiae 4g, Radix Paeoniae Rubra 6g, Concha Ostreae 17g, Radix Trichosanthis 9g, Cortex Magnoliae Officinalis 20g, Poria 22g, Radix Puerariae 24g, Radix Scutellariae 13g, Semen Cuscutae 8g, Herba Taraxaci 16g, place marmite, add 1.5kg water, boil with high heat first, after change into slow fire, continue to decoct 45 minutes.Cooling, the elimination medicinal residues are taken.Once a day, whenever take medicine and decoct 2 times.

Claims (3)

1. the purpose of this invention is to provide a kind of Chinese prescription for the treatment of cyclomastopathy, this Chinese prescription selects following natural Chinese medicinal herb as active medical material:

JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Endothelium Corneum Gigeriae Galli, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Scrophulariae, Radix Curcumae, Spina Gleditsiae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Radix Platycodonis, Radix Isatidis, Herba Lysimachiae, the Radix Aucklandiae, Radix Paeoniae Rubra, Concha Ostreae, Radix Trichosanthis, Cortex Magnoliae Officinalis, Poria, Radix Puerariae, Radix Scutellariae, Semen Cuscutae, Herba Taraxaci.

2. treat as claimed in claim 1 the Chinese prescription of cyclomastopathy, its using method as medicine is:

The various cleaning with Chinese herbal of selecting are clean, oven dry.Take by weighing each 25g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Endothelium Corneum Gigeriae Galli 18g, Rhizoma Chuanxiong 22g, Radix Salviae Miltiorrhizae 15g, Radix Scrophulariae 9g, Radix Curcumae 5g, Spina Gleditsiae 8g, Radix Codonopsis 11g, Rhizoma Atractylodis Macrocephalae 6g, Radix Bupleuri 12g, Radix Platycodonis 21g, Radix Isatidis 15g, Herba Lysimachiae 7g, Radix Aucklandiae 4g, Radix Paeoniae Rubra 6g, Concha Ostreae 17g, Radix Trichosanthis 9g, Cortex Magnoliae Officinalis 20g, Poria 22g, Radix Puerariae 24g, Radix Scutellariae 13g, Semen Cuscutae 8g, Herba Taraxaci 16g, place marmite, add 1.5kg water, boil with high heat first, after change into slow fire, continue to decoct 45 minutes.Cooling, the elimination medicinal residues are taken.

3. treat as claimed in claim 1 the Chinese prescription of cyclomastopathy, the dosage forms such as the ointment of making by the method for extracting, patch, spray.