CN108524897A - A kind of drug and preparation method thereof for treating type of deficiency of both QI and YIN functional consitipation - Google Patents

A kind of drug and preparation method thereof for treating type of deficiency of both QI and YIN functional consitipation Download PDF

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Publication number
CN108524897A
CN108524897A CN201810711277.3A CN201810711277A CN108524897A CN 108524897 A CN108524897 A CN 108524897A CN 201810711277 A CN201810711277 A CN 201810711277A CN 108524897 A CN108524897 A CN 108524897A
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China
Prior art keywords
parts
radix
yin
deficiency
fructus
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CN201810711277.3A
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Inventor
谢胜
刘园园
刘倩
谢洁如
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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Abstract

The invention discloses a kind of drugs and preparation method thereof for treating type of deficiency of both QI and YIN functional consitipation, the drug for treating type of deficiency of both QI and YIN functional consitipation includes honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, deer horn glue, Semen Cuscutae, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, fructus amomi, ginger, cassia twig, fructus cannabis, raw oyster, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, Schisandra chinensis, wheat, pawpaw, Radix Codonopsis, donkey-hide gelatin, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, fructus crataegi cuneatae, auxiliary material.The present invention treats based on supplementing qi and nourishing yin, filling liver kidney, replenishing essence blood, and adjusted comprehensively to each internal organs according to deficiency of both qi and yin physique characteristic, actual situation is differentiated, constitution is biased, accomplishes that bowl spares has clearly, it mends without stagnant, comprehensive adjustment whole body qi and blood, negative and positive, reaches balance whole body negative and positive state.

Description

A kind of drug and preparation method thereof for treating type of deficiency of both QI and YIN functional consitipation
Technical field
The present invention relates to technical field of traditional Chinese medicines, the drug and its system of specifically a kind for the treatment of type of deficiency of both QI and YIN functional consitipation Preparation Method.
Background technology
Functional consitipation (FunctionalConstipation, FC) refers to the constipation caused by non-device matter reason, in work( In energy property gastrointestinal disease Rome Ⅲ criteria, FC shows as bowel frequency reduction, continues difficult defecation or defecation is felt not to the utmost, and do not meet intestines The diagnostic criteria of irritable syndrome (IBS).Epidemiologic data shows that constipation incidence in China's is 3%~17%.China Beijing Chronic functional constipation incidence is 6.07% in 18~70 years old crowd in area.With Chinese society accelerated development, people's rhythm of life Increasingly accelerate, competitive pressure increases nervous degree, and dietary structure the various composite factors such as refines and influences further in addition Down so that the incidence of FC rises year by year, modern life quality is seriously affected.Constipation such as can not only cause hemorrhoid, split at the podexes disease The generation of disease, moreover it is possible to induce and aggravate various cardiovascular and cerebrovascular diseases, serious or even induction colon cancer, threat to life.Modern times doctor It learns studies have shown that many factors such as pathogenic factors and age, gender, area, eating habit, the living habit of constipation are related, As traditional biological medical model changes to Bio-psycho-social Medical Mode, more and more directions are studied to disease incidence Psychology, social factor, Recent study find that psychologic factors are also to lead to one of Risk factors of functional consitipation.Mesh Before think, the pathogenesis of constipation mainly with brain-gut axis exception, gastrointestinal motility disorder, Cajal interstitial cells are abnormal, hormone is different Often, abnormal, Defecation dynamics exception of neurotransmitter etc. is closely related.Functional consitipation is classified as " constipation " scope in traditional Chinese medicine, Ancient books records the different names of disease such as " rear unfavorable ", " difficulty in defecation ", " secret puckery ".Chinese medicine thinks the heresy of constipation main cause diseases caused by external factors fever and chills, interior Hinder diet feelings will, physically weak after being ill, yang blood and qi deficiency etc., sick position is and closely related with taste lung liver kidney in large intestine.Spleen deficiency transmits It is powerless, stop in waste matter, cause large intestine conduction function not normal, forms constipation;Stomach is connected with intestines, stomach excessive heat, passes large intestine down, burns bright Tianjin Liquid, large intestine excess heat, dry stool accumulating in the intestine can be at constipation;The lung and the large intestine being interior-exteriorly related, the scorching of lung move down large intestine, then large intestine conduction function It is not normal, form constipation;Liver controlling conveyance and dispersion mechanism of qi, if irritability stasis, the stagnation of the circulation of vital energy is not all right, and internal organs gas cannot be unimpeded;Five liquid of kidney master and take charge of two Just, if the deficiency of the kidney yin, enteron aisle loses profit, and large intestine loses in warm and transmit powerless if the insufficiency of the kidney yang, and constipation can cause Constipation.And in clinical practice, asthenic symptoms constipation is relatively conventional, is especially very with type of deficiency of both QI and YIN constipation.At present for function Property constipation treatment, at present clinically often use cathartic, dynamics-promoting medicine, probiotics, rectal mucosa protective agent, biofeedback treat The drug therapies such as method and operative treatment, effect vary with each individual, and Long-term taking medicine, some patientss is often needed to be likely to occur diarrhea after medication Equal side reactions, clinical therapeutic efficacy is up for improving;Study of evidence based medicine confirms that traditional Chinese medicine is pacified in terms for the treatment of functional consitipation Entirely, effectively, the clinical symptoms that can improve Patients with Functional Constipation have apparent advantage in terms of general curative effect, reduce recurrence Rate.Common traditional Chinese medicine for oral administration has a decoction and pill, and decoction decocting is cumbersome, poor taste, and patient compliance is poor, and pill absorbs, is aobvious Effect is slow, flavour of a drug dose is fixed, it is difficult to reach dialectical treatmert therapeutic effect.Based on upper, Chinese medicine is processed into herbal paste, not only can overcome the disadvantages that The deficiency of decoction of medicinal ingredients and pill is also equipped with the advantage of decoction of medicinal ingredients and pill, and such as significant in efficacy, few side effects, patient compliance are good, carry Storage is convenient, in good taste.
Invention content
The purpose of the present invention is to provide a kind for the treatment of both manifestation and root cause of disease, effects to mitigate lasting treatment type of deficiency of both QI and YIN functionality just Secret drug and preparation method thereof, to solve the problems mentioned in the above background technology.
To achieve the above object, the present invention provides the following technical solutions:
A kind of drug for treating type of deficiency of both QI and YIN functional consitipation includes according to the raw material of parts by weight:18-22 parts of honey-fried licorice root, life Ground 56-64 parts, Radix Ophiopogonis 28-32 part, 28-32 parts of Os Draconis, 2.5-3.5 parts of safflower, 12-18 parts of the root of bidentate achyranthes, 4.5-5.5 parts of radix bupleuri, 4.5-5.5 parts of deer horn glue, 18-22 parts of Semen Cuscutae, 4.5-5.5 parts of dried orange peel, 8-12 parts of Gorgon fruit, 12-18 parts of the fruit of glossy privet, Radix Glycyrrhizae 4.5- 5.5 parts, 4.5-5.5 parts of fructus amomi, 8-12 parts of ginger, 8-12 parts of cassia twig, 28-32 parts of fructus cannabis, 28-32 parts of raw oyster, Radix Angelicae Sinensis 18- 22 parts, 8-12 parts of radix paeoniae rubra, 4.5-5.5 parts of Fructus Aurantii, 12-18 parts of matrimony vine, 18-22 parts of Herba Cistanches, 18-22 parts of Poria cocos, Schisandra chinensis 8- 12 parts, 28-32 parts of wheat, 12-18 parts of pawpaw, 12-18 parts of Radix Codonopsis, 8-12 parts of donkey-hide gelatin, 28-32 parts of jujube, 5 parts of peach kernel, Rhizoma Chuanxiong 8-12 parts, 4.5-5.5 parts of campanulaceae, 12-18 parts of faenum graecum, 18-22 parts of lotus seeds, 8-12 parts of mantis egg-case, 18-22 parts of fushen, Chinese yam 36-44 parts, 12-18 parts of Radix Paeoniae Alba, 18-22 parts of fructus crataegi cuneatae, 640-760 parts of auxiliary material.
As a further solution of the present invention:
It is described treatment type of deficiency of both QI and YIN functional consitipation drug, include according to the raw material of parts by weight:19-21 parts of honey-fried licorice root, life Ground 58-62 parts, Radix Ophiopogonis 29-31 part, 29-31 parts of Os Draconis, 2.8-3.2 parts of safflower, 14-16 parts of the root of bidentate achyranthes, 4.8-5.2 parts of radix bupleuri, 4.8-5.2 parts of deer horn glue, 19-21 parts of Semen Cuscutae, 4.8-5.2 parts of dried orange peel, 9-11 parts of Gorgon fruit, 14-16 parts of the fruit of glossy privet, Radix Glycyrrhizae 4.8- 5.2 parts, 4.8-5.2 parts of fructus amomi, 9-11 parts of ginger, 9-11 parts of cassia twig, 29-31 parts of fructus cannabis, 29-31 parts of raw oyster, Radix Angelicae Sinensis 19- 21 parts, 9-11 parts of radix paeoniae rubra, 4.8-5.2 parts of Fructus Aurantii, 14-16 parts of matrimony vine, 19-21 parts of Herba Cistanches, 19-21 parts of Poria cocos, Schisandra chinensis 9- 11 parts, 29-31 parts of wheat, 14-16 parts of pawpaw, 14-16 parts of Radix Codonopsis, 9-11 parts of donkey-hide gelatin, 29-31 parts of jujube, peach kernel 4.8-5.2 Part, 9-11 parts of Rhizoma Chuanxiong, 4.8-5.2 parts of campanulaceae, 14-16 parts of faenum graecum, 19-21 parts of lotus seeds, 9-11 parts of mantis egg-case, fushen 19-21 Part, 38-42 parts of Chinese yam, 14-16 parts of Radix Paeoniae Alba, 19-21 parts of fructus crataegi cuneatae, 671-729 parts of auxiliary material.
As a further solution of the present invention:
It is described treatment type of deficiency of both QI and YIN functional consitipation drug, include according to the raw material of parts by weight:20 parts of honey-fried licorice root, Radix Rehmanniae 60 Part, 30 parts of Radix Ophiopogonis, 30 parts of Os Draconis, 3 parts of safflower, 15 parts of the root of bidentate achyranthes, 5 parts of radix bupleuri, 5 parts of deer horn glue, 20 parts of Semen Cuscutae, 5 parts of dried orange peel, 10 parts of Gorgon fruit, 15 parts of the fruit of glossy privet, 5 parts of Radix Glycyrrhizae, 5 parts of fructus amomi, 10 parts of ginger, 10 parts of cassia twig, 30 parts of fructus cannabis, 30 parts of raw oyster, 20 parts of Radix Angelicae Sinensis, 10 parts of radix paeoniae rubra, 5 parts of Fructus Aurantii, 15 parts of matrimony vine, 20 parts of Herba Cistanches, 20 parts of Poria cocos, 10 parts of Schisandra chinensis, 30 parts of wheat, wood 15 parts of melon, 15 parts of Radix Codonopsis, 10 parts of donkey-hide gelatin, 30 parts of jujube, 5 parts of peach kernel, 10 parts of Rhizoma Chuanxiong, 5 parts of campanulaceae, 15 parts of faenum graecum, lotus seeds 20 Part, 10 parts of mantis egg-case, 20 parts of fushen, 40 parts of Chinese yam, 15 parts of Radix Paeoniae Alba, 20 parts of fructus crataegi cuneatae, 700 parts of auxiliary material.
As a further solution of the present invention:
The auxiliary material includes according to the raw material of parts by weight:230-270 parts of yellow rice wine, 45-55 parts of arillus longan, 140-160 parts of honey, core 180-220 parts of peach kernel, 45-55 parts of Semen sesami nigrum.
As a further solution of the present invention:
The auxiliary material includes according to the raw material of parts by weight:240-260 parts of yellow rice wine, 48-52 parts of arillus longan, 145-155 parts of honey, core 190-210 parts of peach kernel, 48-52 parts of Semen sesami nigrum.
As further scheme of the invention:
The auxiliary material includes according to the raw material of parts by weight:250 parts of yellow rice wine, 50 parts of arillus longan, 150 parts of honey, 200 parts of walnut kernel, 50 parts of Semen sesami nigrum.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 10-14h with water immersion;
(2)The 40-60min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 4- 6h stirs removal surfactant foam while decocting;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi is added, slow boiling heats 30- 50min crosses 80 mesh and sieves 2-3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Honey-fried licorice root, Radix Rehmanniae, Radix Angelicae Sinensis, radix paeoniae rubra benefiting qi and nourishing yin blood-nourishing in the present invention;Radix Codonopsis, jujube invigorating heart gas, enriching spleen-QI;Ah Glue, Radix Ophiopogonis, fructus cannabis, peach kernel relax bowel;Ginger, cassia twig yang-tonic tongmai;Os Draconis, raw oyster, fushen are transquilization with heavy material;Deer horn Glue, Semen Cuscutae, matrimony vine, the root of bidentate achyranthes, Herba Cistanches, the fruit of glossy privet, faenum graecum, mantis egg-case, lotus seeds filling liver kidney, benefiting essence-blood moisten defaecation;Trifoliate orange Gas under the wide intestines of shell, campanulaceae, Rhizoma Chuanxiong;Pawpaw, dried orange peel, Gorgon fruit, fructus amomi, Chinese yam, fructus crataegi cuneatae, Poria cocos strengthening the spleen and replenishing qi, to help the wet fortune of water Row;Schisandra chinensis, wheat nourishing heart blood, help the motive;Radix Paeoniae Alba, radix bupleuri are soothing the liver reason spleen;Safflower invigorate blood circulation, to help gas row;Radix Glycyrrhizae QI invigorating Invigorating the spleen, coordinating the drug actions of a prescription.
Compared with prior art, the beneficial effects of the invention are as follows:
The present invention treats based on supplementing qi and nourishing yin, filling liver kidney, replenishing essence blood, and complete to each internal organs according to deficiency of both qi and yin physique characteristic Face is adjusted, and differentiates actual situation, and constitution is biased, is accomplished that bowl spares has clearly, is mended without stagnant, comprehensive adjustment whole body qi and blood, negative and positive reach flat Weigh whole body negative and positive state, and by dialectical treatmert, herbal paste intervention, the dialectical selection present invention are carried out to type of deficiency of both QI and YIN functional consitipation Herbal paste carries out supplementing qi and nourishing yin, relaxes bowel, achievees the purpose that treatment.
Present invention is generally directed to the treatments of type of deficiency of both QI and YIN functional consitipation, and due to the correlation of constitution, treatment is set out Point is started with from constitution, can be also used for treatment functional dyspepsia FD, atrophic gastritis, hypertension, diabetes, urinary system Calculus, astigmatism, pulmonary fibrosis, hyperthyroidism, hypoferric anemia, alpastic anemia, tumor chemoradiotherapy be postoperative, The impairment of both QI and YIN constitutions such as anxiety disorder, sleep disturbance syndrome, chronic fatigue syndrome, caput femoris necrosis, Sjogren syndrome, cheilitis State crowd.
Description of the drawings
Fig. 1 is the medicine preparation flow diagram of the present invention.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Embodiment 1
Referring to Fig. 1, a kind of drug for treating type of deficiency of both QI and YIN functional consitipation, includes according to the raw material of parts by weight:Honey-fried licorice root 18 parts, 56 parts of Radix Rehmanniae, 28 parts of Radix Ophiopogonis, 28 parts of Os Draconis, 2.5 parts of safflower, 12 parts of the root of bidentate achyranthes, 4.5 parts of radix bupleuri, 4.5 parts of deer horn glue, Tu 18 parts of silk, 4.5 parts of dried orange peel, 8 parts of Gorgon fruit, 12 parts of the fruit of glossy privet, 4.5 parts of Radix Glycyrrhizae, 4.5 parts of fructus amomi, 8 parts of ginger, 8 parts of cassia twig, fire 28 parts of edestan, 28 parts of raw oyster, 18 parts of Radix Angelicae Sinensis, 8 parts of radix paeoniae rubra, 4.5 parts of Fructus Aurantii, 12 parts of matrimony vine, 18 parts of Herba Cistanches, 18 parts of Poria cocos, 8 parts of Schisandra chinensis, 28 parts of wheat, 12 parts of pawpaw, 12 parts of Radix Codonopsis, 8 parts of donkey-hide gelatin, 28 parts of jujube, 5 parts of peach kernel, 8 parts of Rhizoma Chuanxiong, campanulaceae 4.5 Part, 12 parts of faenum graecum, 18 parts of lotus seeds, 8 parts of mantis egg-case, 18 parts of fushen, 36 parts of Chinese yam, 12 parts of Radix Paeoniae Alba, 18 parts of fructus crataegi cuneatae, auxiliary material 640 parts.The auxiliary material includes according to the raw material of parts by weight:230 parts of yellow rice wine, 45 parts of arillus longan, 140 parts of honey, walnut kernel 180 Part, 45 parts of Semen sesami nigrum.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 10h with water immersion;
(2)The 40min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 4h, on one side Decoct the surfactant foam of stirring removal on one side;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi, slow boiling heating is added 30min crosses 80 mesh and sieves 2 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 2
A kind of drug for treating type of deficiency of both QI and YIN functional consitipation includes according to the raw material of parts by weight:19 parts of honey-fried licorice root, Radix Rehmanniae 58 It is part, 29 parts of Radix Ophiopogonis, 29 parts of Os Draconis, 2.8 parts of safflower, 14 parts of the root of bidentate achyranthes, 4.8 parts of radix bupleuri, 4.8 parts of deer horn glue, 19 parts of Semen Cuscutae, old 4.8 parts of skin, 9 parts of Gorgon fruit, 14 parts of the fruit of glossy privet, 4.8 parts of Radix Glycyrrhizae, 4.8 parts of fructus amomi, 9 parts of ginger, 9 parts of cassia twig, 29 parts of fructus cannabis, life It is 29 parts of oyster, 19 parts of Radix Angelicae Sinensis, 9 parts of radix paeoniae rubra, 4.8 parts of Fructus Aurantii, 14 parts of matrimony vine, 19 parts of Herba Cistanches, 19 parts of Poria cocos, 9 parts of Schisandra chinensis, small 29 parts of wheat, 14 parts of pawpaw, 14 parts of Radix Codonopsis, 9 parts of donkey-hide gelatin, 29 parts of jujube, 4.8 parts of peach kernel, 9 parts of Rhizoma Chuanxiong, 4.8 parts of campanulaceae, faenum graecum 14 parts, 19 parts of lotus seeds, 9 parts of mantis egg-case, 19 parts of fushen, 38 parts of Chinese yam, 14 parts of Radix Paeoniae Alba, 19 parts of fructus crataegi cuneatae, 671 parts of auxiliary material.It is described Auxiliary material includes according to the raw material of parts by weight:240 parts of yellow rice wine, 48 parts of arillus longan, 145 parts of honey, 190 parts of walnut kernel, Semen sesami nigrum 48 Part.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 10h with water immersion;
(2)The 45min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 4.5h, one Side decocts the surfactant foam of stirring removal on one side;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi, slow boiling heating is added 35min crosses 80 mesh and sieves 3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 3
A kind of drug for treating type of deficiency of both QI and YIN functional consitipation includes according to the raw material of parts by weight:20 parts of honey-fried licorice root, Radix Rehmanniae 60 Part, 30 parts of Radix Ophiopogonis, 30 parts of Os Draconis, 3 parts of safflower, 15 parts of the root of bidentate achyranthes, 5 parts of radix bupleuri, 5 parts of deer horn glue, 20 parts of Semen Cuscutae, 5 parts of dried orange peel, 10 parts of Gorgon fruit, 15 parts of the fruit of glossy privet, 5 parts of Radix Glycyrrhizae, 5 parts of fructus amomi, 10 parts of ginger, 10 parts of cassia twig, 30 parts of fructus cannabis, 30 parts of raw oyster, 20 parts of Radix Angelicae Sinensis, 10 parts of radix paeoniae rubra, 5 parts of Fructus Aurantii, 15 parts of matrimony vine, 20 parts of Herba Cistanches, 20 parts of Poria cocos, 10 parts of Schisandra chinensis, 30 parts of wheat, wood 15 parts of melon, 15 parts of Radix Codonopsis, 10 parts of donkey-hide gelatin, 30 parts of jujube, 5 parts of peach kernel, 10 parts of Rhizoma Chuanxiong, 5 parts of campanulaceae, 15 parts of faenum graecum, lotus seeds 20 Part, 10 parts of mantis egg-case, 20 parts of fushen, 40 parts of Chinese yam, 15 parts of Radix Paeoniae Alba, 20 parts of fructus crataegi cuneatae, 700 parts of auxiliary material.The auxiliary material is according to weight Amount part raw material include:250 parts of yellow rice wine, 50 parts of arillus longan, 150 parts of honey, 200 parts of walnut kernel, 50 parts of Semen sesami nigrum.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 12h with water immersion;
(2)The 50min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 5h, on one side Decoct the surfactant foam of stirring removal on one side;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi, slow boiling heating is added 40min crosses 80 mesh and sieves 3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 4
A kind of drug for treating type of deficiency of both QI and YIN functional consitipation includes according to the raw material of parts by weight:21 parts of honey-fried licorice root, Radix Rehmanniae 62 It is part, 31 parts of Radix Ophiopogonis, 31 parts of Os Draconis, 3.2 parts of safflower, 16 parts of the root of bidentate achyranthes, 5.2 parts of radix bupleuri, 5.2 parts of deer horn glue, 21 parts of Semen Cuscutae, old 5.2 parts of skin, 11 parts of Gorgon fruit, 16 parts of the fruit of glossy privet, 5.2 parts of Radix Glycyrrhizae, 5.2 parts of fructus amomi, 11 parts of ginger, 11 parts of cassia twig, 31 parts of fructus cannabis, 31 parts of raw oyster, 21 parts of Radix Angelicae Sinensis, 11 parts of radix paeoniae rubra, 5.2 parts of Fructus Aurantii, 16 parts of matrimony vine, 21 parts of Herba Cistanches, 21 parts of Poria cocos, Schisandra chinensis 11 Part, 31 parts of wheat, 16 parts of pawpaw, 16 parts of Radix Codonopsis, 11 parts of donkey-hide gelatin, 31 parts of jujube, 5.2 parts of peach kernel, 11 parts of Rhizoma Chuanxiong, 5.2 parts of campanulaceae, 16 parts of faenum graecum, 21 parts of lotus seeds, 11 parts of mantis egg-case, 21 parts of fushen, 42 parts of Chinese yam, 16 parts of Radix Paeoniae Alba, 21 parts of fructus crataegi cuneatae, auxiliary material 729 Part.The auxiliary material includes according to the raw material of parts by weight:It is 260 parts of yellow rice wine, 52 parts of arillus longan, 155 parts of honey, 210 parts of walnut kernel, black 52 parts of sesame.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 14h with water immersion;
(2)The 55min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 5.5h, one Side decocts the surfactant foam of stirring removal on one side;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi, slow boiling heating is added 45min crosses 80 mesh and sieves 3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Embodiment 5
Referring to Fig. 1, a kind of drug for treating type of deficiency of both QI and YIN functional consitipation, includes according to the raw material of parts by weight:Honey-fried licorice root 22 parts, 64 parts of Radix Rehmanniae, 32 parts of Radix Ophiopogonis, 32 parts of Os Draconis, 3.5 parts of safflower, 18 parts of the root of bidentate achyranthes, 5.5 parts of radix bupleuri, 5.5 parts of deer horn glue, Tu Silk 22 parts, 5.5 parts of dried orange peel, 12 parts of Gorgon fruit, 18 parts of the fruit of glossy privet, 5.5 parts of Radix Glycyrrhizae, 5.5 parts of fructus amomi, 12 parts of ginger, 12 parts of cassia twig, 32 parts of fructus cannabis, 32 parts of raw oyster, 22 parts of Radix Angelicae Sinensis, 12 parts of radix paeoniae rubra, 5.5 parts of Fructus Aurantii, 18 parts of matrimony vine, 22 parts of Herba Cistanches, Poria cocos 22 Part, 12 parts of Schisandra chinensis, 32 parts of wheat, 18 parts of pawpaw, 18 parts of Radix Codonopsis, 12 parts of donkey-hide gelatin, 32 parts of jujube, 5 parts of peach kernel, 12 parts of Rhizoma Chuanxiong, 5.5 parts of campanulaceae, 18 parts of faenum graecum, 22 parts of lotus seeds, 12 parts of mantis egg-case, 22 parts of fushen, 44 parts of Chinese yam, 18 parts of Radix Paeoniae Alba, fructus crataegi cuneatae 22 Part, 760 parts of auxiliary material.The auxiliary material includes according to the raw material of parts by weight:270 parts of yellow rice wine, 55 parts of arillus longan, 160 parts of honey, walnut 220 parts of benevolence, 55 parts of Semen sesami nigrum.
The preparation method of the drug of the treatment type of deficiency of both QI and YIN functional consitipation, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 14h with water immersion;
(2)The 60min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 6h, on one side Decoct the surfactant foam of stirring removal on one side;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi, slow boiling heating is added 50min crosses 80 mesh and sieves 3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
Implement case
1, case selection, patient age range, course of disease time
The functional consitipation for choosing Guangxi University of Chinese Medicine's the first affiliated hospital the spleen-stomach diseases section outpatient service and center outpatient service of preventiveing treatment of disease is suffered from Person 100, is randomly divided into 2 groups.50 patients of herbal paste group of the present invention, wherein man 22, female 28;It is age 20-55 Sui, average (38.56±15.78)Year;It is -36 months March of the course of disease, average(12.45±5.07)Month.It is not husky that 50 patients of Western medicine group give citric acid Must sharp dispersible tablet treatment, wherein man 27, female 23;It is age 18-55 Sui, average(37.08±14.98)Year;Course of disease March -35 Month, it is average(11.45±4.25)Month.
2, diagnostic criteria brief introduction
Doctor trained in Western medicine diagnoses:With reference to FC RomeⅢdiagnostic criterias:After the constipation caused by excluding organic disease, preceding symptom is diagnosed at least Occur 6 months, nearly 3 months symptoms meet following standard person, can determine that as functional consitipation:(1)Including following two points or 2 points More than:1. once defecation feels laborious at least four times;2. at least four times once defecation be it is blocky just or it is hard just;3. extremely Defecation in four times few once has to be felt not to the utmost;4. the defecation at least four times once has anorectal obstruction sense or obstruction Sense;5. once defecation need to 6. one week defecation be less than 3 times with gimmick help at least four times.(2)The nothing if not applying purgatives Soft stool.(3)It not can determine that and be diagnosed as irritable bowel syndrome(IBS).
Tcm diagnosis:Differentiation of symptoms and signs for classification of syndrome standard reference in tcm diagnosis standard《Chinese Internal Medicine》(Sixth version)Symptom quantifies Standard reference《New Chinese medicine guideline of clinical investigations》.Primary symptom:Infrequent defecation time lengthening, it is dry that defecation time extends stool Knot, difficult defecation minor symptom:Shortness of breath and fatigue, spiritlessness and sparing of words, dizziness and tinnitus, soreness and weakness of waist and knees, hectic fever night sweat;Tongue fur pulse condition:Pale tongue or Light red, tongue, arteries and veins are thin and delicate less.Patient has each two of the disease of main symptom and time card in above-mentioned symptom, and combines patient's tongue picture, The patient of pulse condition and the course of disease at three months or more(Without organic disease), you can it is diagnosed as functional consitipation(Deficiency of both qi and yin Type).
3, curative effect determinate standard:
Reference《New Chinese medicine guideline of clinical investigations》The effect of evaluation criteria:Clinical recovery:Stool is normal, or restores to disease Preceding level, other symptoms all disappear or therapeutic index >=90%;It is effective:Constipation is obviously improved, interval time of defecation and just Matter close to normal, or stool is slightly dry and the infrequent defecation time within 72h, other symptoms largely disappear or therapeutic index >= 70%;Effectively:The infrequent defecation time shortens 1d, or the just dry and hard improvement of matter, and other symptoms take a favorable turn or therapeutic index >= 30%;In vain:Constipation and other symptoms are without improvement or therapeutic index < 30%.
Nimodipine method calculating therapeutic index=(Symptom integral after symptom integral-treatment before treatment)Symptom before/treatment Integral ] × 100%.
4, drug application method
Herbal paste group:Herbal paste treatment of the present invention is given, 2 times a day, each 20ML, warm water takes.
Western medicine group:Give Dispersible Mosapride citrate tablets(Chengdu Kanghong Medicine Group Co.ltd, Chinese medicines quasi-word H20031110)5mg is oral, 3 times a day.
5, clinical treatment outcome is shown in Tables 1 and 2.
Table 1:Two groups of pretherapy and post-treatment cardinal symptom integral contrasts
Group n Before treatment After treatment Therapeutic index
Western medicine group 50 13.03±3.15 7.16±1.54*# 0.70±0.15#
Herbal paste group 50 13.10±3.09 4.59±1.28*# 0.81±0.20#
Note:Compared with Western medicine group:*P<0.05, #P<0.01.After treatment, herbal paste group of the present invention is obviously improved patient's cardinal symptom(P <0.05), curative effect is more precisely(P<0.01).
Curative effect is relatively shown in Table 2 after two groups of treatments:
Table 2:Two groups of pretherapy and post-treatment curative effects compare
Group Number of cases Recovery from illness It is effective Effectively In vain Total effective rate
Western medicine group 50 5 10 20 15 70%
Herbal paste group 50 18 22 7 3 94%
Note:Compared with Western medicine group:*P<0.01.After treatment, it is effective compared with Western medicine group that herbal paste group of the present invention treats the disease(P<0.01).
Clinical case is observed:
Case 1:Lee ×, man 56 years old, people from Pingguo County,GuangXi, the course of disease 7 years, symptom difficult defecation, 7-8 days a line, companion's soreness and weakness of waist and knees, It is weak.Pink tongue, tongue is yellowish, and arteries and veins is thin.Colonoscopy no abnormality seen is looked into our hospital's outpatient service.Oral " Dispersible Mosapride citrate tablets " 5mgp.oTid does not improve through treating 2 weeks state of an illness;It is treated through drug of the present invention, it is apparent slow before defecation is relatively treated after treatment 14 days Solution, 2-3 days a line of defecating, after continuing medication 14 days, defecation is unobstructed, and daily a line of defecating, the weak symptom of soreness and weakness of waist and knees is accidental, with Visit half a year no relapse.
Case 2:Liu ×, female, 40 years old, Beihai Fisheries Base Guangxi Province people, the course of disease 2 years, symptom difficult defecation, 2-3 days a line, stool was dry Knot is in sheep dung shape, with seeing dizziness, when there is tinnitus, two side of body secret anguish occasionally to there is premenstrual spargosis to keenly feel, pink tongue, tongue is few, and arteries and veins is thin and delicate. Once medical to local hospital, " functional consitipation " is diagnosed after improving coherence check, is taken orally " Dispersible Mosapride citrate tablets " , there are alleviation in 5mgp.oTid, when symptom.Mood is unhappy, then medical to our hospital, is treated through drug of the present invention, after treating 10 days, stool Daily a line, excrement matter is still dry and hard, and symptom is relieved after continual cure January, 1 year no relapse of follow-up.
Case 3:×, man, 27 years old, Rongshui Guangxi people from county, the course of disease 1 year, symptom defecation time was longer, and defecation inability is remaining Without significant discomfort.The red few tongue of tongue, arteries and veins are thin.Colonoscopy no abnormality seen is looked into our hospital's outpatient service.Oral " Dispersible Mosapride citrate tablets " Remission after 5mgp.oTid, but be discontinued after symptom repeatedly;It being treated through drug of the present invention, symptom is relieved after treatment 14 days, Treat January after defecation it is normal, just when strong, 2 years no relapse of follow-up.
Case 4:Old ×, female, 65 years old, people from Liuzhou, 5-year courses, symptom difficult defecation, 5-6 days a line, excrement matter was inclined Dry, even is in sheep dung shape, dizzy after an action of the bowels with night hectic fever, weak.Tongue is red, few tongue, and arteries and veins is thin and delicate.Colonoscopy is looked into our hospital's outpatient service to show " having no organic disease " takes orally " Dispersible Mosapride citrate tablets " 5mgp.oTid, and there is alleviation in when symptom, is unsatisfied with treatment Effect;It is treated through drug of the present invention, symptom is relieved after treating January, and no recurrence was observed during the follow-up period of 6 months.
Case 5:Gong ×, man, 77 years old, Guangxi people from Guigang, the course of disease 3 years, symptom difficult defecation, defecation time extension, 5-7 days A line is just done, dry eyes and astringent eyes, no abdominal distension abdominal pain, receive can, difference of sleeping, the red few tongue of tongue, arteries and veins is thin.Colonoscopy, which is looked into, in our hospital's outpatient service has no different Often.Oral " Dispersible Mosapride citrate tablets " 5mgp.oTid symptoms have no improvement;Then it examines, treats, control through drug of the present invention Symptom is relieved after treating 15 days, and no recurrence was observed during the follow-up period of 6 months.
Benefiting qi and nourishing yin blood-nourishing of the present invention, relaxes bowel, yang-tonic tongmai:Using zhigancao decoction as main ingredient in side, honey-fried licorice root, life Ground, Radix Angelicae Sinensis, radix paeoniae rubra with benefiting qi and nourishing yin blood-nourishing, Radix Angelicae Sinensis can blood-nourishing but also promoting blood circulation, enrich blood without stagnant blood;It is equipped with Radix Codonopsis, jujube benefit The motive, enriching spleen-QI, painstaking effort agitate it is strong for the basic of the whole body QI-blood circulation, then with cassia twig, ginger yang-tonic tongmai, Maitong then blood Row, gas row, the QI-blood circulation whole body, far then defecate tune up to internal organs, help and are relaxed bowel with donkey-hide gelatin, Radix Ophiopogonis, fructus cannabis, peach kernel, sample It takes into account.It is transquilization with heavy material:" disorder of the stomach leading to insomnia with restlessness ", internal organs are obstructed, and taste are become estranged, then uneasy sleeping at night, thus give Os Draconis, life it is male Oyster, fushen are transquilization with heavy material.Filling liver kidney, benefiting essence-blood moisten defaecation:The in love product of deer horn glue flesh and blood, tonifying yin sun is with metaplasia essence and blood, Tu Son, matrimony vine, the root of bidentate achyranthes, Herba Cistanches, the fruit of glossy privet, faenum graecum, mantis egg-case, lotus seeds play the work(to tonify the liver and kidney altogether, to help essence and blood to generate, profit Intestines defaecation.Asthenic yin, then being difficult of sun, Herba Cistanches, the root of bidentate achyranthes have the work(of warming and invigorating kidney Yang again.Gas under wide intestines:The lung and the large intestine being interior-exteriorly related, Lung qi must drop, and internal organs is so incensed that logical, therefore gas under quasi- Fructus Aurantii, campanulaceae, the wide intestines of Rhizoma Chuanxiong.Strengthening the spleen and replenishing qi, to help the wet operation of water:The strong fortune of temper, It is then that stomach and internal organs run body fluid, water is capablely wet, and constipation must be controlled, therefore with pawpaw, dried orange peel, Gorgon fruit, fructus amomi, Chinese yam, fructus crataegi cuneatae, Fu Siberian cocklebur is intended to strengthening the spleen and replenishing qi.Nourishing heart blood, helps the motive:Deficiency of both qi and yin person, blood vessels agitate inability, the motive not to fill, deficiency of heart-blood, therefore give five Taste, wheat are to help motive painstaking effort to generate.Soothing the liver reason spleen:The constipation of deficiency of both qi and yin is common in after prolonged illness, the common mood of patient Unhappiness, the disease of dysfunction of SHAO YANG, therefore give the soothing the liver reason spleen of Radix Paeoniae Alba, radix bupleuri.Invigorate blood circulation, to help blood:Safflower invigorate blood circulation, side In largely use help essence and blood medicine, therefore give safflower be intended to reinforce Radix Angelicae Sinensis promoting circulation of blood work(, make benefit without stagnant.It replenishes qi to invigorate the spleen, reconciles All medicines:Radix Glycyrrhizae has the work(to replenish qi to invigorate the spleen, this side is with focusing on coordinating the drug actions of a prescription.
The present invention expands the model that Chinese medical culture product treats common disease of digestive system by treating FC with herbal paste It encloses, does not only reach good therapeutic effect, and can be adjusted according to the biased of constitution, elimnation for excess and tonification for deficiency, mend without stagnant, adjustment Energy and blood of human body, negative and positive make human body be in equilibrium state, raise internal organs, and supplementing qi and nourishing yin makes negative and positive of qi and blood be attributed to kidney basic.It is logical The treatment of this method is crossed, the clinical symptoms of type of deficiency of both QI and YIN FC can not only be alleviated, also fundamentally solves the difficulty that treatment is easily recurred Topic, achievees the purpose that search for the primary cause of disease in treatment.Present invention effect is significantly, few side effects, patient compliance are good, it is convenient, in good taste to carry storage, For the pattern of current Chinese medicine modernization development, meet social development needs.It is a further object of the present invention to provide the systems of the drug Make method, medicinal material is added water to cook, remove slag, after concentration, add stiff semiliquid preparations made of honey, rule are provided for the making of herbal paste Model and guidance.Present invention is generally directed to the treatment of type of deficiency of both QI and YIN FC, due to the correlation of constitution, the starting point for the treatment of is from constitution Start with, can be also used for treatment functional dyspepsia FD, atrophic gastritis, hypertension, diabetes, stone in urinary system, dissipates Light, pulmonary fibrosis, hyperthyroidism, hypoferric anemia, alpastic anemia, tumor chemoradiotherapy be postoperative, anxiety disorder, The impairment of both QI and YIN constitution status people such as sleep disturbance syndrome, chronic fatigue syndrome, caput femoris necrosis, Sjogren syndrome, cheilitis Group.
The present invention, which has type of deficiency of both QI and YIN FC patient, to be coordinated gastrointestinal motility, promotes defecation power, adjusts micro ecology of gastrointestinal tract Reach functions of loosening bowel relieving constipation, it can also be by tonifying the liver and kidney, adjusting internal organs negative and positive of qi and blood, and reach the adjustment to constitution, from root Disease is treated on this.By largely using herbal paste of the present invention, it is found that the clinical efficacy for the treatment of type of deficiency of both QI and YIN FC is demonstrate,proved better than other Type, while treating constipation main symptom, other accompanying symptoms are also effectively improved, and are such as had a delicate constitution, and colourless god is tired, the tired lazy speech of limb, Body is become thin, dizziness and tinnitus, vexed insomnia, hectic fever night sweat, soreness of waist and knee etc..It has:1, treating both manifestation and root cause of disease.It breaks through doctor trained in Western medicine and controls Treat limitation, advantage of the succession Traditional Chinese Medicine Chinese medicine in treating disease, while treating disease, can adjust each internal organs qi and blood, Negative and positive make body be in equilibrium state;2, other accompanying symptoms improve, and herbal paste adjustment viscera is biased through the invention, other Minor symptom is also effectively relieved;3, from doctor trained in Western medicine angle, this can lubricate enteron aisle and increase enteron aisle moisture, promotes stomach Bowel movement and defecation, the quantity for increasing colon C ajal interstitial cells, the content of adjusting enteric nervous mediator and hormone, are controlled with reaching The purpose for the treatment of.4, effect mitigates lasting, which starts with from the essence for the treatment of disease, is improved at all, effect will be permanent It is uneasy to recur, make up the deficiency of western medical treatment;5, patient compliance is good, and instructions of taking is simple, in good taste, significant in efficacy, patient It is easily accepted by.The 3-4 course for the treatment of is taken, has the function that relax bowel, it can be with across-the-board regulation constitution.
It is compared with conventional medicine, the unique distinction of herbal paste of the present invention is shown:1, it is used for deficiency of both qi and yin and embodies Chinese medical discrimination The characteristics of by diagnosis and treatment disease is controlled;Human body is adjusted comprehensively with numerous medicines, embodies the overall situation thought of Chinese medicine Overall View.2, of the invention The numerous drug interactions of herbal paste, oral rear rapid decompose absorbs after cream is made, and it is dynamic to play coordination gastrointestinal motility, promotion defecation Power, the effect for adjusting micro ecology of gastrointestinal tract.The pathogenesis for fundamentally solving FC, reaches therapeutic effect.3, it is based on the present invention The characteristics of herbal paste, is easy to be accepted by patients, and has good clinical efficacy and wide social demand, is worth clinical expansion and fortune With.4, it finds to treat by the medicine by a large amount of clinical observation, high efficiency is uneasy to recur, fundamentally solves functional The drawbacks of easily being recurred after gastrointestinal disease treatment.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective Various changes can be made.

Claims (7)

1. a kind of drug for treating type of deficiency of both QI and YIN functional consitipation, which is characterized in that include according to the raw material of parts by weight:It processs sweet 18-22 parts careless, 56-64 parts of Radix Rehmanniae, Radix Ophiopogonis 28-32 part, 28-32 parts of Os Draconis, 2.5-3.5 parts of safflower, 12-18 parts of the root of bidentate achyranthes, bavin 4.5-5.5 parts of Hu, 4.5-5.5 parts of deer horn glue, 18-22 parts of Semen Cuscutae, 4.5-5.5 parts of dried orange peel, 8-12 parts of Gorgon fruit, fruit of glossy privet 12- 18 parts, 4.5-5.5 parts of Radix Glycyrrhizae, 4.5-5.5 parts of fructus amomi, 8-12 parts of ginger, 8-12 parts of cassia twig, 28-32 parts of fructus cannabis, raw oyster 28-32 parts, 18-22 parts of Radix Angelicae Sinensis, 8-12 parts of radix paeoniae rubra, 4.5-5.5 parts of Fructus Aurantii, 12-18 parts of matrimony vine, 18-22 parts of Herba Cistanches, Poria cocos 18-22 parts, 8-12 parts of Schisandra chinensis, 28-32 parts of wheat, 12-18 parts of pawpaw, 12-18 parts of Radix Codonopsis, 8-12 parts of donkey-hide gelatin, jujube 28-32 Part, 5 parts of peach kernel, 8-12 parts of Rhizoma Chuanxiong, 4.5-5.5 parts of campanulaceae, 12-18 parts of faenum graecum, 18-22 parts of lotus seeds, 8-12 parts of mantis egg-case, Fu 18-22 parts refreshing, 36-44 parts of Chinese yam, 12-18 parts of Radix Paeoniae Alba, 18-22 parts of fructus crataegi cuneatae, 640-760 parts of auxiliary material.
2. the drug for the treatment of type of deficiency of both QI and YIN functional consitipation according to claim 1, which is characterized in that according to parts by weight Raw material include:19-21 parts of honey-fried licorice root, 58-62 parts of Radix Rehmanniae, Radix Ophiopogonis 29-31 part, 29-31 parts of Os Draconis, 2.8-3.2 parts of safflower, 14-16 parts of the root of bidentate achyranthes, 4.8-5.2 parts of radix bupleuri, 4.8-5.2 parts of deer horn glue, 19-21 parts of Semen Cuscutae, 4.8-5.2 parts of dried orange peel, Gorgon fruit 9- 11 parts, 14-16 parts of the fruit of glossy privet, 4.8-5.2 parts of Radix Glycyrrhizae, 4.8-5.2 parts of fructus amomi, 9-11 parts of ginger, 9-11 parts of cassia twig, fructus cannabis 29-31 parts, 29-31 parts of raw oyster, 19-21 parts of Radix Angelicae Sinensis, 9-11 parts of radix paeoniae rubra, 4.8-5.2 parts of Fructus Aurantii, 14-16 parts of matrimony vine, Herba Cistanches 19-21 parts, 19-21 parts of Poria cocos, 9-11 parts of Schisandra chinensis, 29-31 parts of wheat, 14-16 parts of pawpaw, 14-16 parts of Radix Codonopsis, donkey-hide gelatin 9-11 Part, 29-31 parts of jujube, 4.8-5.2 parts of peach kernel, 9-11 parts of Rhizoma Chuanxiong, 4.8-5.2 parts of campanulaceae, 14-16 parts of faenum graecum, lotus seeds 19-21 Part, 9-11 parts of mantis egg-case, 19-21 parts of fushen, 38-42 parts of Chinese yam, 14-16 parts of Radix Paeoniae Alba, 19-21 parts of fructus crataegi cuneatae, auxiliary material 671-729 Part.
3. the drug for the treatment of type of deficiency of both QI and YIN functional consitipation according to claim 1, which is characterized in that according to parts by weight Raw material include:20 parts of honey-fried licorice root, 60 parts of Radix Rehmanniae, 30 parts of Radix Ophiopogonis, 30 parts of Os Draconis, 3 parts of safflower, 15 parts of the root of bidentate achyranthes, 5 parts of radix bupleuri, 5 parts of deer horn glue, 20 parts of Semen Cuscutae, 5 parts of dried orange peel, 10 parts of Gorgon fruit, 15 parts of the fruit of glossy privet, 5 parts of Radix Glycyrrhizae, 5 parts of fructus amomi, 10 parts of ginger, osmanthus 10 parts of branch, 30 parts of fructus cannabis, 30 parts of raw oyster, 20 parts of Radix Angelicae Sinensis, 10 parts of radix paeoniae rubra, 5 parts of Fructus Aurantii, 15 parts of matrimony vine, 20 parts of Herba Cistanches, Fu 20 parts of Siberian cocklebur, 10 parts of Schisandra chinensis, 30 parts of wheat, 15 parts of pawpaw, 15 parts of Radix Codonopsis, 10 parts of donkey-hide gelatin, 30 parts of jujube, 5 parts of peach kernel, Rhizoma Chuanxiong 10 Part, 5 parts of campanulaceae, 15 parts of faenum graecum, 20 parts of lotus seeds, 10 parts of mantis egg-case, 20 parts of fushen, 40 parts of Chinese yam, 15 parts of Radix Paeoniae Alba, fructus crataegi cuneatae 20 Part, 700 parts of auxiliary material.
4. according to the drug of any treatment type of deficiency of both QI and YIN functional consitipations of claim 1-3, which is characterized in that described Auxiliary material includes according to the raw material of parts by weight:230-270 parts of yellow rice wine, 45-55 parts of arillus longan, 140-160 parts of honey, walnut kernel 180- 220 parts, 45-55 parts of Semen sesami nigrum.
5. according to the drug of any treatment type of deficiency of both QI and YIN functional consitipations of claim 1-3, which is characterized in that described Auxiliary material includes according to the raw material of parts by weight:240-260 parts of yellow rice wine, 48-52 parts of arillus longan, 145-155 parts of honey, walnut kernel 190- 210 parts, 48-52 parts of Semen sesami nigrum.
6. according to the drug of any treatment type of deficiency of both QI and YIN functional consitipations of claim 1-3, which is characterized in that described Auxiliary material includes according to the raw material of parts by weight:250 parts of yellow rice wine, 50 parts of arillus longan, 150 parts of honey, 200 parts of walnut kernel, Semen sesami nigrum 50 Part.
7. a kind of preparation method of the drug for the treatment of type of deficiency of both QI and YIN functional consitipation as described in any one of claims 1-3, It is characterized in that, is as follows:
(1)Weigh each raw material according to parts by weight, and by honey-fried licorice root, Radix Rehmanniae, Radix Ophiopogonis, Os Draconis, safflower, the root of bidentate achyranthes, radix bupleuri, Tu Son, dried orange peel, Gorgon fruit, the fruit of glossy privet, Radix Glycyrrhizae, ginger, cassia twig, fructus cannabis, Radix Angelicae Sinensis, radix paeoniae rubra, Fructus Aurantii, matrimony vine, Herba Cistanches, Poria cocos, five Taste, wheat, pawpaw, Radix Codonopsis, jujube, peach kernel, Rhizoma Chuanxiong, campanulaceae, faenum graecum, lotus seeds, mantis egg-case, fushen, Chinese yam, Radix Paeoniae Alba, south Hawthorn impregnates 10-14h with water immersion;
(2)The 40-60min that is decocted first is added in Chinese medicine machine in raw oyster, the other drugs of above-mentioned immersion are then added, then decoct 4- 6h stirs removal surfactant foam while decocting;
(3)Liquid is filtered to take out, the dregs of a decoction add cold water to decoct again, and recurrence is decocted 3 times, put and are concentrated in pot after filtering the liquid mixing of gained;
(4)So that it is dissolved deer horn glue and donkey-hide gelatin heating, add into above-mentioned concentrated medicament, fructus amomi is added, slow boiling heats 30- 50min crosses 80 mesh and sieves 2-3 times, then small fire boils paste;
(5)Auxiliary material receipts cream is added and is fabricated to herbal paste to obtain the final product.
CN201810711277.3A 2018-07-03 2018-07-03 A kind of drug and preparation method thereof for treating type of deficiency of both QI and YIN functional consitipation Pending CN108524897A (en)

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Application publication date: 20180914