CN105727163A - A traditional Chinese medicine formula for treating liver cancer and a preparing method thereof - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine formula for treating liver cancer and a preparing method thereof. The traditional Chinese medicine formula comprises a medicine for oral administration and a medicine for external use. The medicine for oral administration is prepared from 10-15 parts by weight of ginseng, 10-15 parts by weight of liquorice root, 10-15 parts by weight of virgate wormwood herb, 6-10 parts by weight of cape jasmine fruit, 5-10 parts by weight of common buried rubber, 5-10 parts by weight of zedoray rhizome, 5-10 parts by weight of pangolin scales, 4-8 parts by weight of orange fruit, 2-4 parts by weight of oyster shell, 2-4 parts by weight of barbated skullcup herb, 2-4 parts by weight of paris polyphylla, 4-8 parts by weight of hedyotis, 4-6 parts by weight of herba patriniae, 6-10 parts by weight of honeycomb, 6-10 parts by weight of milkvetch root, 10-15 parts by weight of tangshen and 10-15 parts by weight of largehead atractylodes rhizome. The medicine for external use is prepared from 3-5 parts by weight of pseudobulbus cremastrae seu pleiones, 10-15 parts by weight of Chinese gall, 15-20 parts by weight of knoxia root, 3-5 parts by weight of common andrographis herb, 10-15 parts by weight of caper euphorbia seed, 5-10 parts by weight of radix notoginseng, 5-10 parts by weight of borneol, 6-10 parts by weight of ocimum gratissimum and 10-15 parts by weight of dried tangerine peel. The medicine for external use is used for soaking feet, thus stimulating liver meridian acupoints and promoting blood circulation, and the medicine for oral administration is used in cooperation for tonifying yin, protecting the liver and regulating liver and spleen metabolism, thus boosting immunity and saving the life of a patient.

Description

A kind of Chinese medicine formula treating hepatocarcinoma and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, particularly to a kind of Chinese medicine formula treating hepatocarcinoma and preparation method thereof.

Background technology

Hepatocarcinoma and liver malignancy, be the commonly encountered diseases in surgical diseases and frequently-occurring disease, and liver malignancy can be divided into constitutional and the big class of Secondary cases two.Characters of Primary Malignant Tumors of Liver originates from epithelium or the mesenchymal tissue of liver, and the former is called primary hepatocarcinoma, is that China is occurred frequently, very harmful malignant tumor；The latter is called sarcoma, comparatively rare compared with primary hepatocarcinoma.Secondary cases or title secondary liver cancer mean that the malignant tumor of the multiple organ origin of whole body is invaded to liver, are generally more common in the hepatic metastases of the organ malignant tumours such as stomach, biliary tract, pancreas, Colon and rectum, ovary, uterus, lung, mammary gland.

Owing to liver is the maximum parenchymatous organ of human body, undertaking all kinds of important metabolic function of human body, therefore, liver is once occur that malignant tumor will cause involving the serious consequence of life；Again owing to liver has abundant supply of blood flow, in close relations with the important feature of human body such as postcava, portal vein, biliary system etc., liver malignancy incidence of occult, invasive growth is quick, so its treatment very difficulty.Modern medicine mainly adopts operation, radiation and chemotherapy for the treatment of hepatocarcinoma, but all defective property of these methods, wherein only early stage patient just can carry out operative treatment, operative treatment is the means of local treatment, tumor cell for transferring in blood or its hetero-organization is like water off a duck's back, and Radiotherapy chemotherapy can effectively hinder cancerous cell, but can kill normal cell again simultaneously and cause that the immunologic function of patient is suppressed, more complication occurs, brings very big damage to patient body.Chinese patent (CN103041290A) discloses a kind of Chinese medicine treating hepatocarcinoma, patient's body constitution can be strengthened, strengthen patient's appetite, strengthen the resistance of patient, long-term taking can suppress and prevent cancerous cell pathological changes, but effective instability, uses the patient that cannot be carried out operative treatment and has some limitations.

Summary of the invention

The present invention is according to the deficiencies in the prior art, it is provided that one is matched by the outer medicine of oral medicinal herb, it is possible to suppress tumor propagation, harmonizing the liver and spleen metabolism, Chinese medicine formula of enhancing immunity treatment hepatocarcinoma and preparation method thereof.

The present invention provides a kind of Chinese medicine formula treating hepatocarcinoma, it is made up of oral medicine and medicine for external use, wherein oral medicine is formulated by the raw material of Chinese medicine of following parts by weight: Radix Ginseng 10-15 part, Radix Glycyrrhizae 10-15 part, Herba Artemisiae Scopariae 10-15 part, Fructus Gardeniae 6-10 part, Rhizoma Sparganii 5-10 part, Rhizoma Curcumae 5-10 part, Squama Manis 5-10 part, Fructus Aurantii 4-8 part, Concha Ostreae 2-4 part, Herba Scutellariae Barbatae 2-4 part, Rhizoma Paridis 2-4 part, Herba Hedyotidis Diffusae 4-8 part, Herba Patriniae 4-6 part, Nidus Vespae 6-10 part, Radix Astragali 6-10 part, Radix Codonopsis 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part；

Wherein medicine for external use is formulated by the raw material of Chinese medicine of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 3-5 part, Galla Chinensis 10-15 part, Radix Knoxiae 15-20 part, Herba Andrographis 3-5 part, Semen Euphorbiae 10-15 part, Radix Notoginseng 5-10 part, Borneolum Syntheticum 5-10 part, Ocimum Basilicum 6-10 part, Pericarpium Citri Reticulatae 10-15 part.

A kind of Chinese medicine formula treating hepatocarcinoma, oral medicine is preferably formulated by the raw material of Chinese medicine of following parts by weight: Radix Ginseng 13 parts, 12 parts of Radix Glycyrrhizae, Herba Artemisiae Scopariae 13 parts, Fructus Gardeniae 8 parts, Rhizoma Sparganii 8 parts, Rhizoma Curcumae 8 parts, Squama Manis 8 parts, Fructus Aurantii 6 parts, Concha Ostreae 3 parts, Herba Scutellariae Barbatae 3 parts, Rhizoma Paridis 3 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 5 parts, 8 parts of Nidus Vespae, the Radix Astragali 8 parts, Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.

A kind of Chinese medicine formula treating hepatocarcinoma, medicine for external use is preferably formulated by the raw material of Chinese medicine of following parts by weight: Herba Patriniae 6 parts, Pseudobulbus Cremastrae Seu Pleiones 4 parts, Galla Chinensis 12 parts, Radix Knoxiae 17 parts, Herba Andrographis 4 parts, Semen Euphorbiae 14 parts, Radix Notoginseng 6 parts, Borneolum Syntheticum 7 parts, Ocimum Basilicum 8 parts, Pericarpium Citri Reticulatae 14 parts.

A kind of method of Chinese medicine formula preparing treatment hepatocarcinoma, is made up of following steps: 1) oral medicine weighs raw material of Chinese medicine by above-mentioned weight portion, and add cold water, do not have medical material 4-6cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 35-40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged；2) medicine for external use weighs raw material of Chinese medicine by above-mentioned weight portion and repeats step one, takes out medicinal liquid and pours in foot basin, and adding temperature in foot basin is the hot water of 35-45 DEG C, and foot stretches in foot basin and soaks 15-20 minute.

Using method, takes a secondary oral medicine, and uses a secondary medicine for external use foot bath before sleeping every night.10 days courses for the treatment of.

Pharmacology analysis:

Radix Ginseng: sweet in the mouth, micro-hardship, property is put down.Return spleen, lung, heart channel.There are the effects such as good defying age, resisting fatigue, the immunity of raising human body, nervous system regulation and excited hemopoietic system function.Improve the microcirculation of middle-aged and elderly people, improve memory, learning capacity.It is usually used in treating various types of senile dementia, is particularly suited for the diseases such as heart spleen qi-blood deficiency syndrome, or double lung qi virtual loss, spiritlessness and weakness, empty short, the spontaneous perspiration sudden collapse of cough with asthma.Heating flu, cough with copious phlegm, hyperactivity of hesrt-fire and liver-fire, damp and hot accumulate resistance, dyspepsia not change person is cautious use of.

Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Can spleen reinforcing stomach function regulating, Yiqi and vein recovery.QI invigorating invigorating middle warmer；Relieving spasm to stop pain；Nourishing the lung to arrest cough；Eliminating fire and detoxication；Coordinating the actions of various ingredients in a prescription.Cure mainly asthenia lack of appetite；Leanness yellowish complexion；Shortness of breath and palpitation；Stomachache loose stool；Extremity contraction urgency pain；Hysteria；Cough and asthma；Laryngopharynx swelling and pain；Ulcerative carbuncle swells and ache；Infantile carbuncle.

Herba Artemisiae Scopariae: bitter in the mouth, pungent, cold nature.Return spleen, stomach, liver, gallbladder meridian.Clearing away heat-damp and promoting diuresis, jaundice eliminating.The effects such as curing mainly the pharmaceutical researches such as jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis and have function of gallbladder promoting, liver function protecting is antipyretic, antiinflammatory, blood fat reducing, coronary dilating.

Fructus Gardeniae: bitter in the mouth, cold.GUIXIN, lung, tri-jiao channel.There is heat clearing away, pathogenic fire purging, removing heat from blood；Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache, there is the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.

Rhizoma Sparganii: acrid in the mouth, hardship, property is put down.Return liver, spleen channel.Can removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Controlling lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, swollen pain under the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury.Skin ulcer swells hard.

Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Can circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain；Early cervical carcinoma.

Squama Manis: salty in the mouth, cold nature.Return liver, stomach warp.Can subside a swelling routed carbuncle, search wind active, stimulating milk secretion of stimulating the menstrual flow.Controlling carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external is stopped blooding.

Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.Can regulating the flow of QI to ease the stomach, row stagnant relieving distension.Coerce the stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion for breast, stop in phlegm retention；Gastroptosis, proctoptosis, sub-official prolapses.

Concha Ostreae: salty in the mouth, cold nature.Return liver, gallbladder, kidney channel.Cure mainly tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, metrorrhagia and leukorrhagia of passing out semen, acid regurgitation of having a stomachache.

Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature.Return lung, liver, kidney channel.Heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, fall and flutter the pain of injury, edema, jaundice.

Rhizoma Paridis: bitter in the mouth, cold nature, enter Liver Channel.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and determine convulsion；Curing mainly digestive tract carcinoma, pulmonary carcinoma, the cerebral tumor and malignant lymphoma, clinic is used for the stagnant malignant lymphoma of pyretic toxicity harmony, pulmonary carcinoma, nasopharyngeal carcinoma, the cerebral tumor and digestive system tumor such as gastric cancer, the esophageal carcinoma, hepatocarcinoma etc..

Herba Hedyotidis Diffusae: bitter in the mouth, light, cold in nature；Can heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness；Cure mainly dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery, enteritis, jaundice due to damp-heat, be good at the multiple cancerous protuberance for the treatment of.Modern pharmacology proves, Herba Hedyotidis Diffusae treatment acute icterohepatitis is evident in efficacy.

Herba Patriniae: acrid in the mouth, hardship, cool in nature.Enter stomach, large intestine, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused chest and abdomen pain of the excess-heat stasis of blood, puerperal the disease such as the stagnant stomachache of the stasis of blood.

Nidus Vespae: sweet in the mouth, property is put down.Return stomach warp.Can dispel the wind, merit poison, parasite killing, pain relieving.For toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.

The Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.Can invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not hold back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes.

Radix Codonopsis: sweet in the mouth, property is put down.Return spleen, lung meridian.Cure mainly invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.

The Rhizoma Atractylodis Macrocephalae: this product sweetness and bitterness is warm in nature, main returns taste warp, with spleen invigorating, dampness for Main Function, by forefathers praise for " spleen air making-up and spleen enlivening the first key medicine ".The spleen has the function to transport and transform nutrients because of deficiency of spleen-QI, and transporting is lost strong, often water wet in raw, cause lack of appetite, loose stool or have loose bowels, all cards of phlegm retention, edema, leukorrhagia.

Pseudobulbus Cremastrae Seu Pleiones: sweet in the mouth, micro-pungent, cold in nature, mild toxicity；Return liver, stomach, lung meridian.Can heat-clearing and toxic substances removing；Dispersing swelling and dissipating binds.Main carbuncle malignant boil；Scrofula tuberculosis；Pharyngalgia sore throat；Serpentis, insect bite wound etc..

Galla Chinensis: sour in the mouth, puckery, cold in nature.Return lung, large intestine, kidney channel.Curing mainly pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating stops blooding, removing dampness sore.For chronic cough of deficiency lung, lung-heat phlegmatic cough, chronic diarrhea chronic dysentery, night sweat, quench one's thirst, hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.

Radix Knoxiae: bitter in the mouth, cold in nature.Return lung, spleen, kidney channel.Can detoxicating and resolving stagnation of pathogens, main edema distension；Phlegm retention dyspnea with rapid respiration；Ulcerative carbuncle toxic swelling.

Herba Andrographis: bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, bladder warp.Heat-clearing and toxic substances removing, removing heat from blood, detumescence, dampness.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Controlling acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.

Semen Euphorbiae: acrid in the mouth, warm in nature.Return liver, kidney, large intestine channel.Can relieve oedema or abdominal distension through diuresis or purgation detumescence, broken disease parasite killing.Swelling of harnessing the river is full, phlegm retention, dyspepsia, lump in the abdomen；Women's amenorrhea；Scabies sore, Serpentis stings, warty vegetation.Tool antitumor action.For edema, phlegm retention stagnant distension, constipation and anuresis, blood stasis amenorrhea.

Radix Notoginseng: hemostasis dissipating blood stasis, subduing swelling and relieving pain, has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling down swells and ache.

Borneolum Syntheticum: bitter in the mouth is pungent, slightly warm in nature is nontoxic.Enter the heart, lung meridian.Logical all keys, dissipate stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Controlling apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.Borneolum Syntheticum is applied to local, and sensorineural stimulation is very light, and has the antisepsis of some pain relieving and gentleness, can be used for neuralgia.

Ocimum Basilicum: acrid in the mouth, warm in nature.Relieving the exterior syndrome by diaphoresis, expelling wind and removing dampness, eliminating stasis to stop pain.For anemofrigid cold, headache, pipe abdomen fullness, dyspepsia, stomachache, enteritis, diarrhea, treating swelling and pain by traumatic injury, rheumatic arthritis；Venom, eczema, dermatitis are controlled in external.

Pericarpium Citri Reticulatae: nature and flavor are bitter, pungent, temperature；Return lung, spleen channel；For diseases such as distension and fullness of the chest and abdomen.Pericarpium Citri tangerinae is pungent dissipates logical temperature, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go scattered sluggishness of lung-QI, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, gather around stagnant, chest and diaphragm feeling of fullness and the disease such as stagnation of QI in spleen and stomach, distension and fullness in the abdomen for lung qi；For retention of dampness in middle-JIAO, gastral cavity abdomen painful abdominal mass is swollen, have loose bowels in loose stool, and the disease such as abundant expectoration cough.Pericarpium Citri tangerinae dispelling the damp pathogen with bitter and warm drugs and can spleen invigorating circulation of qi promoting, therefore be usually used in the disease such as retention of dampness in middle-JIAO, vexed, the loose stool greasy fur of gastral cavity abdominal distention, can compatibility Rhizoma Atractylodis, the same Pericarpium Citri Reticulatae of Cortex Magnoliae Officinalis.It is good at again drying dampness to eliminate phlegm, stops up the conventional key medicine of lung, abundant expectoration cough for controlling damp-phlegm, often with the Rhizoma Pinelliae, Poria with using；Reduce for insufficiency of the spleen diet, dyspepsia, and the disease such as nausea and vomiting.This product dampness and can spleen benefiting and stimulating the appetite, it is adaptable to the diseases such as the minimizing of weakness of the spleen and stomach, diet, dyspepsia, loose stool and diarrhea, because of its can spleen invigorating, can regulate the flow of vital energy again, therefore the assistant being frequently used as Qi-tonifying drug makes, can make benefit and not stagnant, prevent heap soil or fertilizer over and around the roots from holding back and do swollen effect.

Secondly, foot's Liver Channel acupuncture point includes point lr 1, TAICHONG acupoint, Acupoint Xingjian and Yongquan acupoint etc., by drug immersion foot, can hype Liver Channel acupuncture point, channels sootheing and network vessel quickening, blood circulation promoting, promote cutaneous circulation, accelerate toxin and discharge, and blood viscosity can be reduced.

Point lr 1: being positioned at big toe by about 2 millimeters of the nail root edge place of second toe side, have adjusting and reinforcing liver and kidney effect, the disease that cures mainly of point lr 1 is: dizzy, stomachache, flesh costalgia, creeping chill disease.In addition, be also considered calm since ancient times and recover mind want cave.This acupuncture point is one of main acupoint on human body liver channel of foot-Jueyin.

TAICHONG acupoint: be positioned at side, instep, in first and second toe metatarsal connecting portion.Upwards move pressure with finger along big toe, secondary toe crack, be depressed into and can feel that tremulous pulse reflects hands, be namely this cave.This cave name means the water wet wind gas of Liver Channel at this to upper punch row.This cave material is the water wet wind gas that Acupoint Xingjian transmits, and to this cave, because being heated, swollen dispersion is that abrupt wind breaks up outside cave, therefore named.Favourable opposition name meaning is same with this cave.

Acupoint Xingjian: be positioned at the 1st, between 2 toes, the dorso-ventral boundary of the hand place, rear of toe web edge, for Liver Channel Yu cave, irritability also can be nursed one's health, Acupoint Xingjian is positioned at side, instep, in halluces, the two red plain boiled pork boundarys depressions in toe joint close rear, somewhat by halluces edge.The symptom that cures mainly of Acupoint Xingjian is: discomfort of being still drank after a night, ocular disease, cramp in the leg, nocturia, hepatic disease, abdomen gas superinverse, intercostal neuralgia, menorrhagia, mucositis etc..

Yongquan acupoint: being positioned at a place of forefoot depression place the 2nd, 3 toe toe seam stricture of vagina head end and first three point of heel line, when firmly bending toe, the recess that front portion, vola occurs is exactly Yongquan acupoint.Pressing Yongquan acupoint gently to be acted on by meridians transmission, regulate autonomic nervous system, expansion blood vessel, promotion cutaneous circulation, quickening toxin are discharged, are reduced blood viscosity.

The Chinese medicine advantage of the present invention: by Traditional Chinese medicine foot bath external, medicine irritation Liver Channel acupuncture point, channels sootheing and network vessel quickening, blood circulation promoting, accelerate toxin and discharge, coordinate the effect of the yin nourishing hepatoprotective of Chinese medicine for oral administration, strengthening vital QI to eliminate pathogenic factors, blood stasis-eliminating and stagnation-dissipating, rapid alleviating pain and detumescence, harmonizing the liver and spleen metabolism, enhancing immunity again, alleviate patient's misery, save patients ' lives.

Wherein, for liver cancer patient, the disease in face is far longer than on health at heart, because hepatocarcinoma is not a disease controlled well, patient suffer from decocting of soul everyday, then doctor and patient household should help liver cancer patient to overcome psychological fear.The mode of concrete nursing it should be noted that following some:

1, after patient learns that oneself suffers from hepatocarcinoma, excessively pessimistic phychologies such as committing suicide often occur, doctor and family numbers of patients don't fail to carry out relevant nursing intervention, and the angle especially standing in patient ponders a problem.Comforting to patient psychologically, hepatocarcinoma patient being irritable and getting angry easily, especially family members should understand forbearing and conciliatory.

2, living environment keeps Clean and comfortable, room ventilation by forced draft.

3, basic nursing should accomplish " six is clean " (oral cavity, face, hair, hand-foot skin, perineum, Bed unit cleaning), " five prevent " (counteracting bedsores, anti-orthostatic hypotension, anti-respiratory system infection, anti-cross infection, anti-urinary system infection), " three nothings " (without excrement, without pendant bed, without scalding), " management " (dietary management).

4, drug safety.Follow the doctor's advice on time, medication according to quantity, carry out medicine keeping.

5, health education, instructs patient oneself to nurse, and corrects bad living habit, non-smoking, does not drink, and improves self nursing ability, it is to avoid the harmful effect that harmful stressor causes, and assists it to maintain psychosoma balance.

6, encourage patient to participate in the life of normal person, participate in gravy jobs, appropriate study, working and learning are established the value of survival of oneself again.

For therapeutic effect, mood is well critically important, notes keeping the good mental status, and this is also the essential condition of rehabilitation.Patient, it is noted that overcome the mental maladjustment of oneself, does not always cherish the feared state of mind, and family members are it is also noted that comfort and give courage and the support that liver cancer patient overcomes the pessimistic feared state of mind, make patient's active treatment disease, establish the resolution defeating the serious illness, keep in a good mood, feel at ease to recuperate.

In life, rational dietary habit must be noted, note not eating the food excessively stimulated, will based on light, the content supplementing some vitamin can eat fresh vegetables more more, also to supplement appropriate high-quality protein, food rich in fat will stop before going too far, want fraction of absorption, fasting crude fibre food, it is to avoid puncture the esophageal veins generation hematemesis of varicose.

Collect 100 liver cancer patients, be randomly divided into treatment group and matched group (taking Sorafenib Tosylate sheet), often organize 50 examples；Man's 50 examples, female 50 example；Age 35-75 year, average 55 years old；The course of disease is the longest 1 year, the shortest 2 weeks, on average about 5 months.Each group patient age symptom is constituted without significant difference；Treatment group patient adopts invention formulation to treat.

Outcome measure:

Effective: cardinal symptom is obviously improved or disappears, focus reduces more than 1/2, and continues more than 1 month.

Effective: cardinal symptom makes moderate progress or is obviously improved, focus reduces more than 1/4, and continues more than 1 month.

Invalid: cardinal symptom is without improving or increasing the weight of, and focus is unchanged or develops.

Use statistical conditions are as follows:

Add up above-mentioned liver cancer patient, within 1 month, be a course for the treatment of, use 2 the course for the treatment of present invention Chinese medicine after, effective and effective totally 5 example, account for 10%, matched group is totally 1 example, accounts for 2%；

After 6 courses for the treatment of, the overall efficiency for the treatment of group is 98%, and the overall efficiency of matched group is 26%；

Further, the patient for the treatment of group is 32 examples in 5 years and more than 5 years, and survival rate accounts for 64%, and matched group only has 3 people, and survival rate only accounts for 6%, it can be seen that, hepatocarcinoma is had obvious therapeutic effect by the present invention, and can extend patients ' lives as far as possible.Further, Sorafenib Tosylate sheet is expensive, about 250,000 one boxes, general patient cannot undertake so high medical fee at all, so can not popularize, but Chinese medicine preparation disclosed in this invention is less costly, general public can accept, thus being beneficial to popularization treatment.

Attached a few example case is described further:

Case 1: poplar, female, 50 years old.Patient's entirety is weak all over, dynamic then pant, dripping sweat, all extremely difficult even getting on or off the bus, and with ascites, the swelling and ache of hepatic region, just vomiting of eating something, and complexion is turned black, after move in my institute, after taking 2 courses for the treatment of of oral and external application medicine Comprehensive Treatment of the present invention, patient is now all right, ascites disappears, sleep of having a meal all has greatly improved, and after 4 courses for the treatment of, lump disappears, and now recovers orthobiosis.

Case 2: grandson, man, 70 years old.Patient is excessive due to the age, is not suitable for operation, successively carried out interventional therapy, but owing to heating, Nausea and vomiting etc. the untoward reaction such as can not be taken food and be terminated intervention.After move in my institute, after taking 2 courses for the treatment of of oral and external application medicine Comprehensive Treatment of the present invention, patient is now all right, and diet, sleep all have greatly improved, and mass reduction after 4 courses for the treatment of, present minimal invasive treatment can take care of oneself.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further elaborated, but the invention is not limited in specific embodiment.

Embodiment 1:

A kind of Chinese medicine formula treating hepatocarcinoma, is made up of oral medicine and medicine for external use, and wherein oral medicine is formulated by the raw material of Chinese medicine of following parts by weight: Radix Ginseng 10 parts, 15 parts of Radix Glycyrrhizae, Herba Artemisiae Scopariae 10 parts, Fructus Gardeniae 10 parts, Rhizoma Sparganii 5 parts, Rhizoma Curcumae 10 parts, Squama Manis 5 parts, Fructus Aurantii 8 parts, Concha Ostreae 2 parts, Herba Scutellariae Barbatae 4 parts, Rhizoma Paridis 2 parts, Herba Hedyotidis Diffusae 8 parts, Herba Patriniae 4 parts, 10 parts of Nidus Vespae, the Radix Astragali 6 parts, Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts；

Wherein medicine for external use is formulated by the raw material of Chinese medicine of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 5 parts, Galla Chinensis 10 parts, Radix Knoxiae 20 parts, Herba Andrographis 3 parts, Semen Euphorbiae 15 parts, Radix Notoginseng 5 parts, Borneolum Syntheticum 10 parts, Ocimum Basilicum 6 parts, Pericarpium Citri Reticulatae 15 parts.

Embodiment 2:

A kind of Chinese medicine formula treating hepatocarcinoma, is made up of oral medicine and medicine for external use, and wherein oral medicine is formulated by the raw material of Chinese medicine of following parts by weight: Radix Ginseng 15 parts, 10 parts of Radix Glycyrrhizae, Herba Artemisiae Scopariae 15 parts, Fructus Gardeniae 6 parts, Rhizoma Sparganii 10 parts, Rhizoma Curcumae 5 parts, Squama Manis 10 parts, Fructus Aurantii 4 parts, Concha Ostreae 4 parts, Herba Scutellariae Barbatae 2 parts, Rhizoma Paridis 4 parts, Herba Hedyotidis Diffusae 4 parts, Herba Patriniae 6 parts, 6 parts of Nidus Vespae, the Radix Astragali 10 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts；

Wherein medicine for external use is formulated by the raw material of Chinese medicine of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 3 parts, Galla Chinensis 15 parts, Radix Knoxiae 15 parts, Herba Andrographis 5 parts, Semen Euphorbiae 10 parts, Radix Notoginseng 10 parts, Borneolum Syntheticum 5 parts, Ocimum Basilicum 10 parts, Pericarpium Citri Reticulatae 10 parts.

Embodiment 3:

A kind of Chinese medicine formula treating hepatocarcinoma, is made up of oral medicine and medicine for external use, and oral medicine is that the raw material of Chinese medicine by following parts by weight is formulated: Radix Ginseng 13 parts, 12 parts of Radix Glycyrrhizae, Herba Artemisiae Scopariae 13 parts, Fructus Gardeniae 8 parts, Rhizoma Sparganii 8 parts, Rhizoma Curcumae 8 parts, Squama Manis 8 parts, Fructus Aurantii 6 parts, Concha Ostreae 3 parts, Herba Scutellariae Barbatae 3 parts, Rhizoma Paridis 3 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 5 parts, 8 parts of Nidus Vespae, the Radix Astragali 8 parts, Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.

A kind of Chinese medicine formula treating hepatocarcinoma, medicine for external use is that the raw material of Chinese medicine by following parts by weight is formulated: Herba Patriniae 6 parts, Pseudobulbus Cremastrae Seu Pleiones 4 parts, Galla Chinensis 12 parts, Radix Knoxiae 17 parts, Herba Andrographis 4 parts, Semen Euphorbiae 14 parts, Radix Notoginseng 6 parts, Borneolum Syntheticum 7 parts, Ocimum Basilicum 8 parts, Pericarpium Citri Reticulatae 14 parts.

Embodiment 4:

A kind of method of Chinese medicine formula preparing treatment hepatocarcinoma, is made up of following steps: 1) oral medicine weighs raw material of Chinese medicine by the weight portion in embodiment 1, and add cold water, do not have medical material 4cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged；2) medicine for external use weighs raw material of Chinese medicine by the weight portion in embodiment 1 and repeats step one, takes out medicinal liquid and pours in foot basin, adds the hot water that temperature is 35 DEG C in foot basin, and foot stretches in foot basin and soaks 20 minutes.

Embodiment 5:

A kind of method of Chinese medicine formula preparing treatment hepatocarcinoma, is made up of following steps: 1) oral medicine weighs raw material of Chinese medicine by the weight portion in embodiment 2, and add cold water, do not have medical material 6cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 35min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged；2) medicine for external use weighs raw material of Chinese medicine by the weight portion in embodiment 2 and repeats step one, takes out medicinal liquid and pours in foot basin, adds the hot water that temperature is 45 DEG C in foot basin, and foot stretches in foot basin and soaks 15 minutes.

Embodiment 6:

A kind of method of Chinese medicine formula preparing treatment hepatocarcinoma, is made up of following steps: 1) oral medicine weighs raw material of Chinese medicine by the weight portion in embodiment 3, and add cold water, do not have medical material 5cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 38min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged；2) medicine for external use weighs raw material of Chinese medicine by the weight portion in embodiment 3 and repeats step one, takes out medicinal liquid and pours in foot basin, adds the hot water that temperature is 40 DEG C in foot basin, and foot stretches in foot basin and soaks 20 minutes.

Below the present invention is described in detail, the above, it is only the preferred embodiments of the invention, when the scope of the present invention can not be limited, namely all done impartial change according to the application scope and modify, all should still belong in covering scope of the present invention.

Claims (4)

1. the Chinese medicine formula treating hepatocarcinoma, it is characterized in that being made up of oral medicine and medicine for external use, wherein oral medicine is formulated by the raw material of Chinese medicine of following parts by weight: Radix Ginseng 10-15 part, Radix Glycyrrhizae 10-15 part, Herba Artemisiae Scopariae 10-15 part, Fructus Gardeniae 6-10 part, Rhizoma Sparganii 5-10 part, Rhizoma Curcumae 5-10 part, Squama Manis 5-10 part, Fructus Aurantii 4-8 part, Concha Ostreae 2-4 part, Herba Scutellariae Barbatae 2-4 part, Rhizoma Paridis 2-4 part, Herba Hedyotidis Diffusae 4-8 part, Herba Patriniae 4-6 part, Nidus Vespae 6-10 part, Radix Astragali 6-10 part, Radix Codonopsis 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part；

Wherein medicine for external use is formulated by the raw material of Chinese medicine of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 3-5 part, Galla Chinensis 10-15 part, Radix Knoxiae 15-20 part, Herba Andrographis 3-5 part, Semen Euphorbiae 10-15 part, Radix Notoginseng 5-10 part, Borneolum Syntheticum 5-10 part, Ocimum Basilicum 6-10 part, Pericarpium Citri Reticulatae 10-15 part.

2. a kind of Chinese medicine formula treating hepatocarcinoma according to claim 1, it is characterised in that: oral medicine is that the raw material of Chinese medicine by following parts by weight is formulated: Radix Ginseng 13 parts, 12 parts of Radix Glycyrrhizae, Herba Artemisiae Scopariae 13 parts, Fructus Gardeniae 8 parts, Rhizoma Sparganii 8 parts, Rhizoma Curcumae 8 parts, Squama Manis 8 parts, Fructus Aurantii 6 parts, Concha Ostreae 3 parts, Herba Scutellariae Barbatae 3 parts, Rhizoma Paridis 3 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 5 parts, 8 parts of Nidus Vespae, the Radix Astragali 8 parts, Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.

3. a kind of Chinese medicine formula treating hepatocarcinoma according to claim 1, it is characterized in that: medicine for external use is that the raw material of Chinese medicine by following parts by weight is formulated: Herba Patriniae 6 parts, Pseudobulbus Cremastrae Seu Pleiones 4 parts, Galla Chinensis 12 parts, Radix Knoxiae 17 parts, Herba Andrographis 4 parts, Semen Euphorbiae 14 parts, Radix Notoginseng 6 parts, Borneolum Syntheticum 7 parts, Ocimum Basilicum 8 parts, Pericarpium Citri Reticulatae 14 parts.

4. the method preparing the as claimed in claim 1 Chinese medicine formula treating hepatocarcinoma, it is characterised in that: be made up of following steps: 1) oral medicine weighs raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 4-6cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 35-40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged；2) medicine for external use weighs raw material of Chinese medicine by above-mentioned weight portion and repeats step one, takes out medicinal liquid and pours in foot basin, and adding temperature in foot basin is the hot water of 35-45 DEG C, and foot stretches in foot basin and soaks 15-20 minute.