CN104784538B - A kind of Chinese medicine preparation and preparation method for the treatment of diabetes - Google Patents

Abstract

The invention discloses a kind of Chinese medicine preparation and preparation method for the treatment of diabetes, this Chinese medicine preparation comprises Radix Ginseng, Radix Rehmanniae Preparata, Poria, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutan, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Fructus Schisandrae Chinensis, Flos Carthami, the Cortex Eucommiae, Cortex Cinnamomi, Rhizoma Coptidis, Fructus Citri Sarcodactylis, Radix Glycyrrhizae etc. 24 taste.Its preparation method is simple, safe and reliable; Formula compatibility of the present invention is reasonable, reinforcing both QI and YIN, clearing heat and moistening dryness promotes the production of body fluid, blood circulation promoting and blood stasis dispelling is antipruritic, eliminate deficiency of both QI and YIN and the mechanisms of causing a disease such as the fire that causes declines, endogenous dryness, phlegm-damp blood stasis, can maintain body metabolism balance, allaying tiredness is weak, excessive thirst polydipsia, rapid digestion of food and polyorexia and peripheral circulation disorders, retinal hemorrhage, skin pruritus symptom.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of diabetes

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetes and preparation method thereof, belong to technical field of traditional Chinese medicine preparation.

Background technology

Diabetes are one of modern several large diseases.The diseases such as it and hypertension, hyperlipemia, cardiovascular and cerebrovascular disease are the diseases occurred frequently in person in middle and old age's stage.Diabetes have the course of disease long, painful large, complication is many, to health multiple organ damage greatly, the not easily feature such as healing, belong to systemic lesion, modern medicine is difficult to means targetedly effectively intervenes, and the treatment means of any local all difficulty has good long-term effect.

Diabetes, the traditional Chinese medical science is referred to as " quenching one's thirst ", and sick position is dirty at lung, stomach, kidney three, and basic pathogenesis is that the deficiency of YIN is scorching, and the deficiency of YIN is this, and scorching is mark, the part of the body cavity above the diaphragm housing the heart and lungs dryness of the lung deficiency of YIN, and body fluid loses in defeated cloth, then stomach is vowed and made moist, and kidney cuts down taste and helps; Middle burnt stomach excessive heat, consumption of body fluid by heat, then upper Tianjin lung that burns, lower consumption kidney yin; Kidney of lower warmer deficiency of YIN, upper scorching lung stomach, causes the dryness of the lung, gastric heat, the deficiency of YIN three burnt with sick.

The so-called three-many-one-little symptom that modern Western medicine is summed up, namely losing weight of the polyuria drunk eaten more more, in fact accurately can not reflect the real features of diabetes, so-called three-many-one-little is not the representative symptom of diabetes, is not merely that islets of langerhans pathological changes is so simple yet.

And the Symptoms of actual diabetes and complexity thereof, it is a systemic lesion of human body.Its symptom mainly contains tired weak, thirsty, easily hungry, and urine frequency, thickness have foam, become thin, dysphoria with feverish sensation in the chest palms and soles, dizzy, blurring of vision, tinnitus, even reaches an advanced stage and there will be circulatory disturbance, tissue rots, retinal hemorrhage blindness, myocardium congestion, a series of complication such as renal failure uremic.We find in long-term clinical observation, diabetes do not have any classical symptom fixed Combination, diabetes are not inherently the pathological changes of one organ thus, but a kind of systemic metabolic disorders of human body integral state, metabolic intermediate does not have effective excretion pathway or metabolic process to occur obstacle.

Based on above understanding, start with from the angle of body metabolism, the selected Chinese crude drug that metabolism can be promoted to carry out and the Chinese crude drug that metabolite is discharged can be promoted, composition of prescription, improve body system metabolism to reach, reduce blood glucose, alleviate or eliminate the effect of relevant symptom.This research finds, early diabetes can effect a radical cure completely, and middle late diabetes effectively can control blood glucose, and eliminate or alleviate related symptoms, delay or prevent the appearance of complication, Late-stage diabetic can reduce the earthquake intensity of complication, alleviates related symptoms etc.

Summary of the invention

The object of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine preparation and preparation method for the treatment of diabetes are provided.

For achieving the above object, the present invention adopts following technical proposals:

A kind of Chinese medicine preparation for the treatment of diabetes, it is be made up of the crude drug of following weight parts: Radix Ginseng 6-10 parts, 15-30 parts, Radix Rehmanniae Preparata, 10-15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 15-30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10-15 parts, Radix Salviae Miltiorrhizae 10-15 parts, Rhizoma Alismatis 10 parts of Fructus Schisandrae Chinensis 6-10 parts, 6-10 parts, Flos Carthami, the Cortex Eucommiae 10-15 parts, Cortex Cinnamomi 1-3 parts, Rhizoma Coptidis 1-3 parts, Rhizoma Phragmitis 10-20 part, Folium Pyrrosiae 10-20 parts, Fructus Atriplicis Sibiricae 10-20 parts, Radix Adenophorae (Radix Glehniae) 10-15 part, Radix Dipsaci 10-15 parts, wick 5-10 parts, Fructus Citri Sarcodactylis 10-15 part, Radix Sophorae Flavescentis 10-15 part, 5-10 parts, Radix Glycyrrhizae.

Preferably, the Chinese medicine preparation of these treatment diabetes is made up of the crude drug of following weight portion: Radix Ginseng 8-10 parts, 18-22 parts, Radix Rehmanniae Preparata, 12-15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 25-30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10-12 parts, Radix Salviae Miltiorrhizae 12-15 parts, Rhizoma Alismatis 10 parts, Fructus Schisandrae Chinensis 6-8 parts, 6-8 parts, Flos Carthami, the Cortex Eucommiae 10-13 parts, Cortex Cinnamomi 1-3 parts, Rhizoma Coptidis 1-3 parts, Rhizoma Phragmitis 10-15 parts, Folium Pyrrosiae 15-20 parts, Fructus Atriplicis Sibiricae 15-20 parts, Radix Adenophorae (Radix Glehniae) 10-15 parts, Radix Dipsaci 10-14 parts, wick 5-10 parts, Fructus Citri Sarcodactylis 10-15 parts, Radix Sophorae Flavescentis 10-15 part, 5-10 parts, Radix Glycyrrhizae.

Preferred further, the Chinese medicine preparation of these treatment diabetes is made up of the crude drug of following weight portion: Radix Ginseng 10 parts, 20 parts, Radix Rehmanniae Preparata, 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Alismatis 10 parts, Fructus Schisandrae Chinensis 6 parts, 6 parts, Flos Carthami, the Cortex Eucommiae 10 parts, Cortex Cinnamomi 3 parts, Rhizoma Coptidis 3 parts, Rhizoma Phragmitis 14 parts, Folium Pyrrosiae 1 part, Fructus Atriplicis Sibiricae 17 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Dipsaci 12 parts, wick 8 parts, Fructus Citri Sarcodactylis 14 parts, Radix Sophorae Flavescentis 15 parts, 10 parts, Radix Glycyrrhizae.

The preparation method of the Chinese medicine preparation of described treatment diabetes is: after each crude drug mixing, add water to 1 ~ 2 times of crude drug gross weight, soak 30 ~ 60min, at 110 ~ 120 DEG C, heat 20 ~ 40min, then reduce temperature to 100 ~ 105 DEG C, continue heating 20 ~ 40min, raised temperature to 110 ~ 120 DEG C again, continue heating 10 ~ 30min, be again cooled to 80 ~ 90 DEG C, heating 10 ~ 20min, cooling, filter, remove slag, after packaging, make oral liquid;

Or after being dried by each crude drug, mixing, pulverizes, and crosses 100 ~ 200 mesh sieves, makes powder.

Detailed directions: oral, every day potion oral liquid, every agent 250ml, sooner or later half an hour is each once after meal, and serveing on 10 days is a course for the treatment of.Depending on the state of an illness, be used in conjunction and can fully recover 3-5 the course for the treatment of.In the later stage, hot water is taken after mixing it with water powder, each 6-10 grams, and twice daily, life-time service, with consolidate curative effect, maintains body metabolism balance.

All stimulating food such as diet Aquatic product raw meat thing, peppery, wine, chicken and duck goose, beef and mutton, pupa are needed during taking this product, should light diet.Otherwise by impact effect, touching difficulty more.

The property of medicine of crude drug used in the present invention is as follows:

Radix Ginseng: sweet in the mouth is slightly cold is warm in nature, flat.Main tonifying five ZANG-organs, peace spirit, determine soul, spasmolytic is throbbed with fear, except pathogen, improving eyesight, happy Fructus Alpiniae Oxyphyllae.Be applicable to adjustment blood pressure, recover the diseases such as cardiac function, neurasthenia and physical weakness.

Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.There is YIN nourishing effect of enriching blood, can be used for blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia, diseases such as also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst.

Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.Compendium of Material Medica: Poria abnormal smells from the patient is light and ooze, and its property is up, born fluid, loosing the interspaces of skin and muscles, grows water source and declines, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, saying its property also; Dong Yuan calls it for the YIN aspect of YANG, fall and under, Yan Qigong is also.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, micro-hardship, enter stomach of foot Yang Ming, spleen meridian.Invigorating middle warmer dampness, slakes thirst and help produce saliva, most strengthening the spleen essence, large nourishing the stomach gas, and the turbid descending is cloudy and enter diet, kind anti-nausea, sending up the lucid YANG and the water paddy that disappears, and can cure and let out profit.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

The Radix Astragali: sweet in the mouth, tepor.It has enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely, Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.

Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.Have and nourish strong, aid digestion, hold back sweating due to debility, effect of antidiarrheal, quench one's thirst for insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes, oliguria frequently, seminal emission, women's leukorrhagia and dyspeptic chronic enteritis.

Fructus Corni: sour in the mouth, puckery, slightly warm in nature.Return liver, kidney channel.There is liver and kidney tonifying, effect of arresting collape syndrome by astringents.Be usually used in vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed, and interior-heat is quenched one's thirst.

Cortex Moutan: cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Nourishing YIN to lower pathogenic fire, separates speckle poison, throat, diuresis stasis.Contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action, and paeonol has the effects such as central inhibitory action and atherosclerosis, diuresis, antiulcer such as calmness, cooling, antipyretic, analgesia, spasmolytic.

Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.

Rhizoma Alismatis: sweet in the mouth, light, cold in nature.Return kidney, urinary bladder channel.Promoting diuresis to eliminate damp pathogen, expels the heat-evil, and changes turbid blood fat reducing.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipemia.

Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature.Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.

Flos Carthami: pungent, temperature.Enter the heart, Liver Channel." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.For promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.

The Cortex Eucommiae: sweet in the mouth, warm in nature.There are liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, admittedly through antiabortive effect.Can treat the lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes is not solid, the diseases such as scrotum pruritus due to damp pathogen.There is rubbish in purged body, strengthen human body cell substance metabolism, prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol, reduces body fat, recovers blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic, stimulating central nervous system, improves leukocyte pharmacological action.

Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.There is benefit fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian, vigorate qi and replenish the blood, effect of tranquilizing by nourishing the heart.For sexual impotence cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, and colic of cold type is suffered from abdominal pain, and dysmenorrhea amenorrhea, dry pharynx lip is dry.Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.

Rhizoma Coptidis, meridian distribution of property and flavor: bitter, cold.GUIXIN, stomach, liver, large intestine channel.Rhizoma Coptidis effect: heat clearing and damp drying, eliminating fire and detoxication.Rhizoma Coptidis cures mainly: damp and hot for gastrointestinal, and vomiting, dysentery, unconsciousness due to high fever, dysphoria and insomnia, heat in blood tells nosebleed, sore swollen toxin, glue ear, eczema, toothache due to stomach-fire.

Rhizoma Phragmitis, meridian distribution of property and flavor: sweet, cold.Attach to the lung and stomach meridians.Rhizoma Phragmitis effect: clearing away heat and promoting production of body fluid, preventing or arresting vomiting, diuresis.Rhizoma Phragmitis cures mainly: hinder excessive thirst for calentura Tianjin, gastropyretic vomiting, lung abscess, cough due to lung-heat.

Folium Pyrrosiae, meridian distribution of property and flavor: bitter sweet, cool; Enter lung, urinary bladder channel.Function cures mainly: relieving stranguria by diuresis, and lung heat clearing expels the heat-evil.Control and drench pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle.

Fructus Atriplicis Sibiricae, property hide return through: bitter, pungent, flat, enter Liver Channel.Function effect: suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.

Radix Adenophorae (Radix Glehniae), has another name called Radix Adenophorae, nature and flavor: sweet in the mouth; Micro-hardship; Cold nature.Gui Jing: return lung; Stomach warp.Function cures mainly: replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Main deficiency of YIN chronic cough; Consumptive disease is coughed expectorant blood; Cough caused by dryness expectorant is few; Deficiency-heat sore throat; Tianjin wound is thirsty.

Radix Dipsaci, has another name called Radix Dipsaci, nature and flavor: tepor, bitter, sweet, pungently returns through liver, kidney.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.For: soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.

Wick, nature and flavor: sweet in the mouth, light, cold nature.Gui Jing: GUIXIN, lung, small intestine meridian.Effect: clearing away heart-fire, diuresis.Cure mainly: for vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.

Fructus Citri Sarcodactylis, nature and flavor: acrid in the mouth, hardship, acid, warm in nature.Gui Jing: return liver, spleen, stomach, lung meridian.Function: have depressed liver-energy dispersing and QI regulating, and helmet pain relieving, effect of drying dampness to eliminate phlegm.Cure mainly: for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted, cough with copious phlegm.

Radix Sophorae Flavescentis, nature and flavor: bitter in the mouth, cold in nature.Gui Jing: GUIXIN, liver, stomach, large intestine, urinary bladder channel.Effect: heat clearing and damp drying, parasite killing, diuresis.Cure mainly: for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.

Radix Glycyrrhizae, meridian distribution of property and flavor: sweet is flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The monarch relation of Raw medicine of the present invention:

Diabetes, the traditional Chinese medical science is referred to as " quenching one's thirst ", and sick main duty is dirty at lung, spleen, kidney three, and basic pathogenesis is deficiency of both QI and YIN, the scorching wet stasis of blood, and deficiency of both QI and YIN is this, and the scorching wet stasis of blood is mark, the part of the body cavity above the diaphragm housing the heart and lungs dryness of the lung deficiency of YIN, and body fluid loses in defeated cloth, therefore aobvious scorching resembling; Middle burnt deficiency of the spleen and heat of the stomach, transporting mistake department, retention of phlegm and dampness; Part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels nephrons is not enough, imbalance of YIN and YANG, decline of the fire from the gate of life deficiency of the kidney, and fire does not return unit, is not enough to warm internal organs body, very aquaticly sends out passive, is not enough to profit and moistens the whole body.The monarch relation of Raw medicine of the present invention:

Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Poria, the Radix Astragali, Rhizoma Dioscoreae, Radix Rehmanniae Preparata, Fructus Corni, Radix Dipsaci, Cortex Cinnamomi, the Cortex Eucommiae, strongly invigorating primordial QI is monarch drug altogether; Radix Adenophorae (Radix Glehniae), Fructus Schisandrae Chinensis, Rhizoma Phragmitis, Yin-nourishing and body fluid promoting, YIN nourishing are ministerial drug altogether, altogether principal drug assistance tonification the five internal organs Yin Yang balancing; Rhizoma Coptidis, Folium Pyrrosiae, Rhizoma Alismatis, wick relieve inflammation or internal heat the relieving restlessness that expels the heat-evil, Fructus Citri Sarcodactylis, Cortex Moutan Radix Salviae Miltiorrhizae, Flos Carthami, blood circulation promoting and blood stasis dispelling, and Fructus Atriplicis Sibiricae, kuhseng anti-itch are adjuvant drug altogether; Radix Glycyrrhizae, coordinating the actions of various ingredients in a prescription, for making medicine.

The invention has the beneficial effects as follows: (1) this formula is with natural edible-plant medicine for raw material, and each component all meets national politics and law regulation.Utilize the comprehensive function of every Chinese medicine, blood glucose can be made after one month to be reduced to normal level, one and a half months can be fully recovered, and cures tracing study in latter 3 months, is normally through hepatic and renal function inspection, and to human non-toxic's side effect, without toleration, instant effect, cure rate is high.

(2) formula compatibility of the present invention is reasonable, reinforcing both QI and YIN, clearing heat and moistening dryness promotes the production of body fluid, blood circulation promoting and blood stasis dispelling is antipruritic, eliminate deficiency of both QI and YIN and the mechanisms of causing a disease such as the fire that causes declines, endogenous dryness, phlegm-damp blood stasis, can maintain body metabolism balance, allaying tiredness is weak, excessive thirst polydipsia, rapid digestion of food and polyorexia and peripheral circulation disorders, retinal hemorrhage, skin pruritus symptom.

Detailed description of the invention:

Below by instantiation, the present invention will be further elaborated, should be noted that following explanation is only to explain the present invention, not limiting its content.

Embodiment 1

The Chinese medicine preparation for the treatment of diabetes is made up of the crude drug of following weight portion: Radix Ginseng 10 parts, 20 parts, Radix Rehmanniae Preparata, 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Alismatis 10 parts, Fructus Schisandrae Chinensis 6 parts, 6 parts, Flos Carthami, the Cortex Eucommiae 10 parts, Cortex Cinnamomi 3 parts, Rhizoma Coptidis 3 parts, Rhizoma Phragmitis 14 parts, Folium Pyrrosiae 1 part, Fructus Atriplicis Sibiricae 17 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Dipsaci 12 parts, wick 8 parts, Fructus Citri Sarcodactylis 14 parts, Radix Sophorae Flavescentis 15 parts, 10 parts, Radix Glycyrrhizae.

The preparation method of the Chinese medicine preparation of described treatment diabetes is: after each crude drug mixing, add water to 1 times of crude drug gross weight, soak 30min, at 110 DEG C, heat 20min, then reduce temperature to 100 DEG C, continue heating 20min, raised temperature to 110 DEG C again, continue heating 10min, be again cooled to 80 DEG C, heating 10min, cooling, filter, remove slag, after packaging, make oral liquid.

Embodiment 2

The Chinese medicine preparation for the treatment of diabetes is made up of the crude drug of following weight portion: Radix Ginseng 6 parts, 15 parts, Radix Rehmanniae Preparata, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 15 portions of Rhizoma Dioscoreaes 15 parts, Fructus Corni 15 parts, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Alismatis 10 parts of Fructus Schisandrae Chinensis 10 parts, 10 parts, Flos Carthami, the Cortex Eucommiae 15 parts, Cortex Cinnamomi 3 parts, Rhizoma Coptidis 3 parts, Rhizoma Phragmitis 20 parts, Folium Pyrrosiae 20 parts, Fructus Atriplicis Sibiricae 20 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Dipsaci 15 parts, wick 10 parts, Fructus Citri Sarcodactylis 15 parts, Radix Sophorae Flavescentis 15 parts, 10 parts, Radix Glycyrrhizae

Preparation method is: after being dried by each crude drug, and mixing, pulverizes, and crosses 100 mesh sieves, makes powder.

Embodiment 3

The Chinese medicine preparation for the treatment of diabetes is made up of the crude drug of following weight portion: Radix Ginseng 8 parts, 25 parts, Radix Rehmanniae Preparata, 14 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 18 portions of Rhizoma Dioscoreaes 15 parts, Fructus Corni 15 parts, Cortex Moutan 12 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Alismatis 10 parts of Fructus Schisandrae Chinensis 8 parts, 8 parts, Flos Carthami, the Cortex Eucommiae 12 parts, Cortex Cinnamomi 2 parts, Rhizoma Coptidis 2 parts, Rhizoma Phragmitis 18 parts, Folium Pyrrosiae 12 parts, Fructus Atriplicis Sibiricae 13 parts, Radix Adenophorae (Radix Glehniae) 12 parts, Radix Dipsaci 14 parts, wick 9 parts, Fructus Citri Sarcodactylis 12 parts, Radix Sophorae Flavescentis 13 parts, 8 parts, Radix Glycyrrhizae

The preparation method of the Chinese medicine preparation of described treatment diabetes is: after each crude drug mixing, add water to 2 times of crude drug gross weight, soak 30min, at 120 DEG C, heat 20min, then reduce temperature to 105 DEG C, continue heating 20min, raised temperature to 120 DEG C again, continue heating 10min, be again cooled to 90 DEG C, heating 10min, cooling, filter, remove slag, after packaging, make oral liquid.

The detailed directions of above embodiment: oral, every day potion oral liquid, every agent 250ml, sooner or later half an hour is each once after meal, and serveing on 10 days is a course for the treatment of.Depending on the state of an illness, be used in conjunction and can fully recover 3-5 the course for the treatment of.In the later stage, hot water is taken after mixing it with water powder, each 6-10 grams, and twice daily, life-time service, with consolidate curative effect, maintains body metabolism balance.

Clinical data:

For showing the therapeutic effect of medicine of the present invention to diabetes, the present invention selects the suitable Patients with 300 Cases of medical history, the state of an illness, age, sex and former Therapeutic Method to be that system is observed temporarily, is divided into 2 groups at random.Treatment group 150 example, man 81 example, female 69 example; 44.5 ~ 76.8 years old age, average (60.65 ± 16.15) year; Diabetic duration 3 ~ 15.2 years, average (6.22 ± 2.51) year; Diabetic duration 0.55 ~ 6.5 year, average (3.85 ± 0.72) year.Matched group 150 example, man 73 example, female 77 example; 42.4 ~ 71.5 years old age, average (56.95 ± 14.55) year; Diabetic duration 2.5 ~ 14.2 years, average (4.88 ± 2.16) year; Diabetic duration 0.3 ~ 5.8 year, average (3.46 ± 1.15) year.The aspects such as 2 groups of patient ages, sex, the course of disease, state of an illness compare, and difference there are no significant meaning (P > 0.05), has comparability.Wherein treatment group stops former medicine one week on former treatment basis, takes the medicine of the embodiment of the present invention 1, every day two doses, potion 250ml, observes 3 courses for the treatment of, within 10 days, is a course for the treatment of; Matched group blood sugar lowering medication routinely, wherein hypoglycemic medicine and dosage and test group match, and the matched group antidiabetic drug of the application adopts diabetes pill.

Detection method is periodic detection fasting glucose (FPG), after the meal 2 hours blood glucoses (2hPG), glucose in urine, fasting insulin (Fins), 2 hours after the meal insulins (2hlns), cholesterol (TC), triglyceride (TG), three-many-one-little present situations.Can be divided into normal (-) according to the degree of its performance, mile abnormality (+), moderate abnormal (++), severe abnormal (+++).

Table 1 is the difference comparsion of FPG, 2hPG, glucose in urine, three-many-one-little after 3 courses for the treatment of of employing 2 groups of Chinese medicine formulas treatment diabetes

Table 2 is the difference comparsion of Fins, 2hlns, TG, TC after 3 courses for the treatment of of employing 2 groups of Chinese medicine formulas treatment diabetes

To have diversity remarkable in the reduction of Chinese medicine formula to blood sugar content of foregoing invention as can be seen from Table 1, fasting glucose content is reduced to 4.5 ± 1.38 from 15.8 ± 0.59,2 hours after the meal, blood sugar content is reduced to 4.28 ± 1.69 from 22.3 ± 0.45, this difference tool is very significant (P < 0.01), but the formula of foregoing invention basic there was no significant difference (P >=0.05) compared with diabetes pill.After taking 3 courses for the treatment of of formula of the present invention, glucose in urine content significance reduces, and this content is reduced to normal urine sugar value, described in patient, the phenomenon of polyphagia, polydipsia, polyuria without, the treatment after 3 courses for the treatment of nearly, body weight reaches normal level substantially.As can be seen from Table 2, take Chinese medicine formula of the present invention, before and after cholesterol and triglyceride, content obviously reduces, after the treatment of 3 courses for the treatment of, substantially normal level is reached, this difference tool is very significant (P < 0.01), and insulin content before the treatment after, within 2 hours after the meal, slightly increase, but difference is little, also difference is little compared with diabetes pill for above-mentioned formula of the present invention, its no significant difference (P > 0.05).After the taking of 1 first quarter moon, diabetes are effected a radical cure substantially, and the cure rate through adding up diabetics reaches 97%, after again through the tracing study of 2 months, hepatic and renal function is all normal, does not find toxic and side effects.

Model case:

Shao Nan, 28 years old, find to suffer from diabetes 1 year, have hereditary medical history, its mother dies from diabetic complication in 49 years old.Examine, readme fatigue is weak, xerostomia, night sweat, and during blood glucose height, fasting blood sugar can reach 20 units (normal 3.9-6.1), once goes into a coma, and surpasses and doubly takes antidiabetic drug fasting blood sugar also in 12 units one.Take the oral liquid 10 days of embodiment 1, after taking, inform, tired weak xerostomia night sweat etc. obviously alleviates.Enjoin it to adhere to taking medicine, after 30 days, incoming all announcement, symptom disappears completely, and when taking half antidiabetic drug, test blood glucose, within normal value.Suggestion one---within two months, take our medicine once (10 days), with consolidate curative effect.So enter the agent of our medicine more than 70 altogether, 10 years so far, follow up a case by regular visits to, situation is stablized, and only needs half to a slice antidiabetic drug.Blood glucose can remain on normal range, non-evident sympton.

Hu Nv, 63 years old, finds to suffer from diabetes two more than ten years, this year exacerbation of symptoms, blood glucose medication is invalid out of control, and hospital doctor trained in Western medicine checks, islets of langerhans organ loses activity, then beats insulin, blood glucose still more than 12.6, urine protein ++.Though slightly improve, but still agonizing.Examine, readme xerostomia mouth heat, head fiber crops eye dusk, weak agitation, time have heating spontaneous perspiration, urine is foamed.Examine the oral liquid 10 days taking embodiment 1, conscious all diseases alleviate, continuous administration 10 days, and symptom is eliminated substantially, detects routine blood test and routine urinalysis (beating insulin), blood glucose 8.1, and urine protein disappearance, feels good.Then advise monthly taking we's conditioning, after half a year, change and quarterly nurse one's health once (taking our medicine medicine 10 days), 3 years so far, in stable condition, somatosensory was substantially good.

Lin Nan, 53 years old, blood glucose 9.1, readme fatigue was weak, and mouth is not thirsty, namely hungry hard to bear less than meal point after meal, slightly dynamic i.e. sweating, fear of cold, hands and feet being not warm, but brothers' heart burns heat sometimes.Take the oral liquid 10 days of embodiment 1, tired weak sense obviously alleviates, and can adhere to that lower meal point is not hungry after meal, sweating alleviates, and fear of cold alleviates, and the heating of brothers' heart disappears.Continue and take medicine totally 40 doses, feel good, blood glucose 5.5, within normal range.Advise it often to detect blood glucose, if be increased significantly, our medicine can be taken earlier.

Geng Nv, 56 years old, blood glucose 11.3 (taking antidiabetic drug), extremely tired weak, thirsty, drink water puzzled, frequently, vision degradation, opposite misknowed face to urine, and hospital diagnosis advanced diabetes, retinal hemorrhage causes blind.Take the oral liquid 10 days of embodiment 3, tired weak alleviation, gently thirsty, take medicine 30 doses, vision is clearly better, and checks to hospital, blood glucose 6.4 (taking antidiabetic drug), and fundus photograph contrasts, and ecchymosis obviously reduces.Patient's confidence increases, and continue and take medicine to 70 doses, vision is almost recovered completely, and health is effectively spry and light, and mouth is thirsty, and not frequently, low dose takes blood sugar lowering Western medicine to urine, blood glucose 5.7.Advise it to keep low dose to take blood sugar lowering Western medicine, seasonality takes our medicine, and nearly 10 years so far, in stable condition, optical fundus is not hemorrhage again, normal visual acuity.

Yu Nan, 61 years old, suffers from diabetes more than 20 years, takes blood sugar lowering Western medicine throughout the year, and tired weak, health pruritus, can't bear to bother, the traditional Chinese medical science of then seeking medical advice.Take the oral liquid 10 days of embodiment 1, tiredly weakly to alleviate, pruritus is obviously alleviated, and continuously takes our medicine to 30 dose, and pruritus is removed, and tired weak basic disappearance, blood sugar lowering Western medicine reduces by half and takes, and glycemic control is in normal range.

Jiang Nan, 48 years old, thirsty, become thin, weak, frequently, slightly dynamic sweating is immoderate, and examination in hospital, is diagnosed as diabetes, blood glucose 9.2, and take blood sugar lowering Western medicine, symptom does not subtract for urine.Take the oral liquid 10 days of embodiment 1, all diseases alleviate, and take to 30 doses, all disease knowing are removed, and feel effectively spry and light, advise take the powder of embodiment 2 its every day, and after half a year, all diseases are not reproduced, and weight recovery, as front, do not take blood sugar lowering Western medicine and detects blood glucose 5.8.

Claims (4)

1. treat the Chinese medicine preparation of diabetes for one kind, it is characterized in that, it is be made up of the crude drug of following weight parts: Radix Ginseng 6-10 parts, 15-30 parts, Radix Rehmanniae Preparata, 10-15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 15-30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10-15 parts, Radix Salviae Miltiorrhizae 10-15 parts, Rhizoma Alismatis 10 parts of Fructus Schisandrae Chinensis 6-10 parts, 6-10 parts, Flos Carthami, the Cortex Eucommiae 10-15 parts, Cortex Cinnamomi 1-3 parts, Rhizoma Coptidis 1-3 parts, Rhizoma Phragmitis 10-20 part, Folium Pyrrosiae 10-20 parts, Fructus Atriplicis Sibiricae 10-20 parts, Radix Adenophorae (Radix Glehniae) 10-15 part, Radix Dipsaci 10-15 parts, wick 5-10 parts, Fructus Citri Sarcodactylis 10-15 part, Radix Sophorae Flavescentis 10-15 part, 5-10 parts, Radix Glycyrrhizae.

2. Chinese medicine preparation as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight portion: Radix Ginseng 8-10 parts, 18-22 parts, Radix Rehmanniae Preparata, 12-15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 25-30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10-12 parts, Radix Salviae Miltiorrhizae 12-15 parts, Rhizoma Alismatis 10 parts, Fructus Schisandrae Chinensis 6-8 parts, 6-8 parts, Flos Carthami, the Cortex Eucommiae 10-13 parts, Cortex Cinnamomi 1-3 parts, Rhizoma Coptidis 1-3 parts, Rhizoma Phragmitis 10-15 parts, Folium Pyrrosiae 15-20 parts, Fructus Atriplicis Sibiricae 15-20 parts, Radix Adenophorae (Radix Glehniae) 10-15 parts, Radix Dipsaci 10-14 parts, wick 5-10 parts, Fructus Citri Sarcodactylis 10-15 parts, Radix Sophorae Flavescentis 10-15 part, 5-10 parts, Radix Glycyrrhizae.

3. Chinese medicine preparation as claimed in claim 2, is characterized in that, be made up of the crude drug of following weight portion: Radix Ginseng 10 parts, 20 parts, Radix Rehmanniae Preparata, 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 15 parts, Fructus Corni 15 parts, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Alismatis 10 parts, Fructus Schisandrae Chinensis 6 parts, 6 parts, Flos Carthami, the Cortex Eucommiae 10 parts, Cortex Cinnamomi 3 parts, Rhizoma Coptidis 3 parts, Rhizoma Phragmitis 14 parts, Folium Pyrrosiae 1 part, Fructus Atriplicis Sibiricae 17 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Dipsaci 12 parts, wick 8 parts, Fructus Citri Sarcodactylis 14 parts, Radix Sophorae Flavescentis 15 parts, 10 parts, Radix Glycyrrhizae.

4. the preparation method of the Chinese medicine preparation of the arbitrary described treatment diabetes of claim 1-3, it is characterized in that: after each crude drug mixing, add water to 1 ~ 2 times of crude drug gross weight, soak 30 ~ 60min, 20 ~ 40min is heated at 110 ~ 120 DEG C, then temperature to 100 ~ 105 DEG C are reduced, continue heating 20 ~ 40min, then raised temperature to 110 ~ 120 DEG C, continue heating 10 ~ 30min, again be cooled to 80 ~ 90 DEG C, heating 10 ~ 20min, cooling, filters, remove slag, after packaging, make oral liquid; Or after being dried by each crude drug, mixing, pulverizes, and crosses 100 ~ 200 mesh sieves, makes powder.