CN102362957B - Chinese prepared medicine for treating deep lupus erythematosus - Google Patents

Chinese prepared medicine for treating deep lupus erythematosus Download PDF

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CN102362957B
CN102362957B CN2011101698568A CN201110169856A CN102362957B CN 102362957 B CN102362957 B CN 102362957B CN 2011101698568 A CN2011101698568 A CN 2011101698568A CN 201110169856 A CN201110169856 A CN 201110169856A CN 102362957 B CN102362957 B CN 102362957B
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radix
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lupus erythematosus
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CN102362957A (en
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王莲芬
渠淑敏
董娜
吴国敏
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Haimen Jinqilin Rosewood Investment and Development Co., Ltd.
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王莲芬
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Abstract

The invention discloses a Chinese patent medicine for treating deep lupus erythematosus and belongs to the technical field of skin disease treatment. According to the technical scheme provided by the invention, the Chinese patent medicine is made from the following medicaments of: by weight, 20-30 parts of fleece-flower root, 15-25 parts of radix paeoniae rubrathe, 15-25 parts of Cortex moutan, 15-25 parts of achyranthcs bidentata blume, 20-30 parts of cornus officinalis, 20-30 parts of Yedo violet, 20-30 parts of Radix Codonopsis, 15-25 parts of Chinese cassia tree, 15-25 parts of Chinese angelica, 15-25 parts of white peony root, 15-25 parts of wolfberry, 15-25 parts of scutellaria baicalensis, 10-15 parts of eucommia, 15-25 parts of lithospermum, 9-16 parts of red sage root, 10-15 parts of Rhizoma anemarrhenae, 10-15 parts of sophora flavescens, 10-20 parts of cornu saigae tataricae, 10-20 parts of duckweed and 10-20 parts of Alisma Orientalis. In comparison with the prior art, the Chinese patent medicine for treating deep lupus erythematosus has effects of eliminating patients' diseases and promoting physical and mental health, is convenient for patients to take, and has outstanding substantive characteristics and marked progress of fast curative effect and no side-effect.

Description

A kind of Chinese patent medicine for the treatment of lupus erythematosus profundus
Technical field
The present invention relates to the treatment technology field of dermatosis, relate in particular to a kind of Chinese patent drug technique field that is used for the treatment of lupus erythematosus profundus.
Background technology
Lupus erythematosus profundus is a kind of of lupus erythematosus.Claiming lupus panniculitis again, is the lupus erythematosus of intermediate form equally.Skin lesion is tuberosity or speckle, is positioned at corium deep layer or subcutaneus adipose tissue, and its size, number are indefinite, the normal or pale red of the surperficial colour of skin, and quality is solid, Immobility.Infringement can betide any position, is most commonly in buccal, buttocks, arm, is shank and chest secondly.Through chronic, the sustainable several months is left over atrophoderma and depression to the several years after the healing.Lupus erythematosus profundus character instability, but individualism can be converted into discoid lupus erythematosus later on, also can be converted into systemic lupus erythematosus (sle), or exist simultaneously with them.
To the research of the pathogenic factor of lupus erythematosus profundus, pathological change, textual criticism and scientific validation are learnt repeatedly, the reason that causes lupus erythematosus profundus and be converted into systemic lupus erythematosus (sle) mainly contains following several: inherited genetic factors according at present; Infective agent; Endocrine factors; The depressed liver and heat transmission that environmental factors forms, flaming of heart-fire in the interior, heat in blood becomes the stasis of blood.In daily life, can bring out lupus erythematosus profundus as improper diet etc.And the medicine for the treatment of lupus erythematosus profundus at present has Chinese medicine, Western medicine, but curative effect does not all make patient satisfaction; And some drug toxicity is bigger, and therapeutic process injures health, has brought many miseries to the patient.
Summary of the invention
Technical problem to be solved by this invention provides a kind of illness with the elimination patient, promotes physical and mental health, has the Chinese patent medicine of the treatment lupus erythematosus profundus that the patient takes medicine conveniently, curative effect is fast, have no side effect simultaneously.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: a kind of Chinese patent medicine for the treatment of lupus erythematosus profundus, and its special character is to be prepared from by following medicaments in part by weight: 20 1 30 parts of Radix Polygoni Multiflori, 15 1 25 parts of Radix Paeoniae Rubra, 15 1 25 parts of Cortex Moutans, 15 1 25 parts of Radix Achyranthis Bidentataes, 20 1 30 parts of Fructus Corni, 20 1 30 parts of Herba Violaes, 20 1 30 parts of Radix Codonopsis, 15 1 25 parts of Cortex Cinnamomis, 15 1 25 parts of Radix Angelicae Sinensis, 15 1 25 parts of the Radix Paeoniae Albas, 15 1 25 parts of Fructus Lycii, 15 1 25 parts of Radix Scutellariaes, 10 1 15 parts of the Cortexs Eucommiae, 15 1 25 parts of Radix Arnebiae (Radix Lithospermi)s, 9 one 16 parts of Radix Salviae Miltiorrhizaes, 10 1 15 parts of Rhizoma Anemarrhenae skins, 10 1 15 parts of Radix Sophorae Flavescentiss, 10 1 20 parts of Cornu Saigae Tataricae, 10 1 20 parts in Herba Spirodelae, 10 1 20 parts of Rhizoma Alismatis.
The preferred version of the medicine of above-mentioned weight proportion is: 22 1 28 parts of Radix Polygoni Multiflori, 18 1 22 parts of Radix Paeoniae Rubra, 18 1 22 parts of Cortex Moutans, 18 1 22 parts of Radix Achyranthis Bidentataes, 22 1 28 parts of Fructus Corni, 22 1 28 parts of Herba Violaes, 22 1 28 parts of Radix Codonopsis, 18 1 22 parts of Cortex Cinnamomis, 18 1 22 parts of Radix Angelicae Sinensis, 18 1 22 parts of the Radix Paeoniae Albas, 18 1 22 parts of Fructus Lycii, 18 1 22 parts of Radix Scutellariaes, 11 1 14 parts of the Cortexs Eucommiae, 18 1 22 parts of Radix Arnebiae (Radix Lithospermi)s, 11 1 14 parts of Radix Salviae Miltiorrhizaes, 12 1 13 parts of Rhizoma Anemarrhenae skins, 11 1 14 parts of Radix Sophorae Flavescentiss, 12 1 18 parts of Cornu Saigae Tataricae, 12 1 18 parts in Herba Spirodelae, 12 1 18 parts of Rhizoma Alismatis.
The preferred plan of the medicine of above-mentioned weight proportion is: 25 parts of Radix Polygoni Multiflori, 20 parts of Radix Paeoniae Rubra, 20 parts of Cortex Moutans, 20 parts of Radix Achyranthis Bidentataes, 25 parts of Fructus Corni, 25 parts of Herba Violaes, 25 parts of Radix Codonopsis, 20 parts of Cortex Cinnamomis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 20 parts of Fructus Lycii, 20 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Anemarrhenae skins, 12 parts of Radix Sophorae Flavescentiss, 15 parts of Cornu Saigae Tataricae, 15 parts in Herba Spirodelae, 15 parts of Rhizoma Alismatis.
Chinese patent medicine described above is made pill, sublimed preparation, powder, tablet, unguentum, decoction and the different oral medicine dosage form of capsule dress powder according to the conventional technology of preparing of Chinese medicine.
Chinese patent medicine described above also contains drug excipient.
The principles of formulating prescriptions of Chinese patent medicine of the present invention are: to regulate the blood flow circulation, painful antipruritic, the cooling blood and dissolving purpura in clearing away heart-fire, expelling wind and removing dampness, kidney tonifying detoxifcation, town, enhancement telangiectasis, improve immune function of human body, thereby reach the purpose for the treatment of deep erythema disease.The present invention has proper, the reasonable recipe of compatibility of drugs, and the effect of its described each herbal medicine is:
Herb Cistanchis: bitter in the mouth, sweet, puckery, slightly warm in nature.Return liver, spleen, kidney channel.Effect cures mainly: nourishing the blood and yin; Loosening bowel to relieve constipation; Preventing the attack (or recurrence) of malaria; Dispel the wind; Detoxifcation.Cure mainly the blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; The dryness of the intestine constipation; Chronic malaria body void; The rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.
Radix Paeoniae Rubra: sour in the mouth, hardship, cool in nature.Go into liver, spleen channel.Effect: clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control the stagnant amenorrhea of the stasis of blood, the hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.
Cortex Moutan: bitter in the mouth, cool in nature, be slightly cold.GUIXIN, liver, kidney, lung meridian.Effect cures mainly: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is flat.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.Be used for soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.Fructus Corni: sour in the mouth, puckery, tepor.Return liver, kidney channel.Function cures mainly: liver and kidney tonifying, essence astringing and desertion stemming.Be used for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse.Interior-heat is quenched one's thirst.
Herba Violae: bitter in the mouth, suffering, cold.GUIXIN, lung meridian.Function with cure mainly: heat-clearing and toxic substances removing.Be used for furuncle, carbuncle, erysipelas, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion and swelling pain, sore throat, mumps, venom.Radix Codonopsis: sweet in the mouth, property are put down.Return spleen, lung meridian.Effect: QI invigorating, promote the production of body fluid, nourish blood.
Cortex Cinnamomi: bitter in the mouth, cold in nature.Go into the heart, liver, stomach, large intestine channel.Function: clearing away heat-fire, dampness detoxifcation.Cure mainly: the calentura heresy go into heart channel hyperpyrexia, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting or rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, Ting ear.
Radix Angelicae Sinensis: sweet in the mouth, suffering, warm in nature.Return liver, the heart, spleen channel.Function with cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Main smelting: menoxenia, abdominal pain during menstruation, metrorrhagia, spontaneous perspiration, night sweat, side of body rib epigastric pain, limb pain twin, headache, dizzy.
Fructus Lycii: sweet in the mouth, property is flat.Return liver, kidney channel.Fructus Lycii has invigorating the liver and kidney, beneficial vital essence, longue meat, improves complexion, makes eye bright and calm the nerves, dispel the wind and control the effect of void, life lengthening, hard muscles and bones.Hepatic and renal YIN deficiency, blood deficiency and yellow complexion, chronic consumptive disease damage of essence, soreness of the waist and knees, disease such as have a dizzy spell there is remarkable result.It is deficient to be used for Liver and kidney, asthenia of essence and blood, and soreness of the waist and knees, dizzy tinnitus, seminal emission, infertile; Deficiency of kidney essence, the xerostomia of quenching one's thirst, frequent micturition red tongue; Essence and blood can not on help in order, eyes is dim-sighted, visual deterioration.
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Function cures mainly: heat clearing and damp drying, and eliminating fire and detoxication, hemostasis, antiabortive.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The Cortex Eucommiae: sweet in the mouth, little suffering, warm in nature.Control the spinal column ache, a little less than the limbs flaccidity, seminal emission, spermatorrhea is had loose bowels just before dawn, asthenia, dribbling urination, uncontrolled urination is itched, and frequent fetal movement, vaginal bleeding during pregnancy are desired to fall, overabundance of amniotic fluid, habitual abortion, hypertension.
Radix Arnebiae (Radix Lithospermi): sweet in the mouth, salty.Function cures mainly: removing heat from blood, invigorate blood circulation the detoxifcation rash.Be used for that the heat in blood poison is contained, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood is used for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention
Radix Salviae Miltiorrhizae: bitter in the mouth, little suffering, cold nature; Go into the heart, spleen, liver, kidney footpath; Effect: have blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, the effect of removing heat from blood detumescence; Cure mainly: blood stasis head, breast, the side of body, abdomen pain, gather, menoxenia, the dysmenorrhea amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, arthralgia, the traumatic injury congestive edema, epidemic febrile disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, red rash scabies.
Rhizoma Anemarrhenae skin: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect: clearing away heat-fire, promote the production of body fluid and moisturize, clearing away heat-fire, the available cards such as epidemic febrile disease excessive heat in QI system and cough due to lung-heat of controlling.
Radix Sophorae Flavescentis: bitter in the mouth; Liver, kidney, large intestine, small intestinal, bladder, heart channel of returning cold in nature.Function cures mainly: heat clearing and damp drying, wind dispelling insecticide.Damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.
Cornu Saigae Tataricae: salty in the mouth, cold in nature.Function: clearing away heat and relieving spasm, suppressing the hyperactive liver to relieve the wind syndrome, removing toxic substances and promoting subsidence of swelling.(relieving spasm by subduing liver-wind liver heat removing and eyesight improving heat-clearing and toxic substances removing) cures mainly: unconsciousness due to high fever, delirium are gone mad, diseases such as infantile convulsion is twitched, conjunctival congestion and swelling pain.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Main smelting: menoxenia, abdominal pain during menstruation, metrorrhagia, spontaneous perspiration, night sweat, side of body rib epigastric pain, limb pain twin, headache, dizzy.
Herba Spirodelae: acrid in the mouth, cold in nature.Nontoxic.Go into lung, liver, spleen channel.Effect: diaphoresis, dispel the wind row water, heat clearing away, detoxifcation.Cure mainly: the hot carbuncle of row when controlling, macule is not saturating, wind heat pain rash, skin pruritus, edema, amenorrhea, the skin ulcer tinea, erysipelas is scalded.
Rhizoma Alismatis: sweet in the mouth is light; Cold in nature.Return kidney; Urinary bladder channel.Function cures mainly: promoting diuresis to eliminate damp pathogen; It is treating stranguria to expel the heat-evil.Cure mainly dysuria; The puckery pain of pyretic stranguria; The edema distension; Have loose bowels; Dizziness due to fluid-retention.
The Chinese medicine and pharmacy theory is thought: in scorchingly hot vehement be lupus erythematosus main diseases because of, the patient of primary disease 90% is with heating, this is the gesture of pathogenic heat aggressiveness.Scorchingly hot pluging with molten metal tied in nutrient blood, thus outer show speckle, in heating is arranged, very the person is evil covers clear key, dusk is raved tic, so the traditional Chinese medical science has " maculae caused by violent heat pathogen ", titles such as " pyretic toxicity are sent out speckle ".Clinical is many with scorchingly hot flourishing type also in acute stage.Study carefully its scorchingly hot origin, have diseases caused by exogenous pathogenic factor and interior life not.The diseases caused by exogenous pathogenic factor pyretic toxicity mostly with to tan by the sun daylight relevant, also has because experiencing rheumatism, accumulates the resistance skin, stays and does not go, and then turns to pyretic toxicity for a long time.In makes pyretic toxicity often can not fire processed by the deficiency of YIN so that give birth in the pathogenic fire, so lose cloudy Tianjin day, YANG toxin syndrome day contains, the formation vicious cycle.
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", all composition comes from the 5th edition medicine that records of China's " pharmacopeia ", all medicines have temperature compensation liver spleen mutually and altogether, the wind dehumidifying of loosing, QI and blood regulating, dredge the meridian passage, blood circulation promoting and blood stasis dispelling, set upright and get rid of evils, regulate immunologic function, improve skin microcirculation, reach treatment and prevention lupus erythematosus profundus disease, determined curative effect, have no side effect various Chinese medicine preparation taking conveniences.
The clinical use result of Chinese patent medicine of the present invention shows to have following advantage:
1, the Chinese medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes comprehensive function treatment and the prevention lupus erythematosus profundus disease of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Acute toxicity test and accumulation toxicity test through white mice and rat show that underproof animal does not see any toxic reaction, compare zero difference through anatomic observation hemogram, liver function, each organs and tissues morphology finding and matched group, prove that its safety of medicine is reliable.
2, Chinese patent medicine preparation of the present invention need not decoct, not have bitterness sense, rich in proteins, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid in the medicine, also contain various trace elements such as Saponin, plant sterol, calcium, be conducive to absorption of human body, health invigorating, and taking convenience.
3, Chinese patent medicine preparation of the present invention not only can effectively be treated the lupus erythematosus profundus disease, and it is also very obvious to the preventive effect of lupus erythematosus profundus, particularly by working in coordination with mutually between the medicine, strengthen medicine and treat characteristic separately, by dredge the meridian passage and adjusting immunologic function, improve healthy energy and physical and mental health and the life quality of patient body inherence, reached the healing rehabilitation efficacy preferably.
Further specify Chinese patent medicine of the present invention to the therapeutic effect for the treatment of lupus erythematosus profundus below by the clinical practice example.
One. the clinical diagnosis standard
The diagnostic criteria that Shanghai rheumatism association (1987) proposes has: (11) butterfly erythema or plate-like erythema; (12) photaesthesia; (13) mouth and nose transmucosal ulcer; (14) non-arthritis deformans or Polyarthralgia; (15) pleuritis or pericarditis; (6) epilepsy merit mental symptom; (17) albuminuria or cylinderuria or hematuria; (8) platelet<10X109/L (100,000/mm3) or leukocyte<4X109/L (4000/mm3) or hemolytic anemia; (9) the antinuclear antibody positive; (10) anti-dsDNA antibody positive or LE cell positive; (11) the anti-Sm antibody positive; (12) C3 reduces; (13) lupus band test (the non-sick position of decreasing) or the kidney biopsy positive.Meet any 4 persons in above-mentioned 13, diagnosable is SLE.The sensitivity of this standard is 95.5%, and specificity is 96.7%, and especially to early-stage cases, sensitivity is high than ARA's.
And lupus erythematosus profundus is wherein a kind of of lupus erythematosus, and its clinical diagnosis standard mainly contains:
Skin is tuberosity or speckle, is positioned at corium deep layer or subcutaneus adipose tissue, and its size, number are indefinite, the normal or pale red of the surperficial colour of skin, and quality is solid, Immobility.Infringement can betide any position, is most commonly in buccal, buttocks, arm, is shank and chest secondly.Through chronic, the sustainable several months is left over atrophoderma and depression to the several years after the healing.
Check foundation:
1, blood routine examination.
2, X ray examination.
3, dialectical inspection.
Two. case selection
The sickness rate of lupus erythematosus profundus is with area, the ethnic group colour of skin and different, prevalence is less in the population of China, put down in writing according to interrelated data: age of onset is in the majority in year at 20-50, account for 80% of sum, for this reason, case selection is whole cases totally 65 examples with door rash prescription on individual diagnosis patient, diagnoses according to " clinical diagnosis standard ": local scleroderma patient's 59 examples, system's sclerosis 6 examples.
Three. curative effect determinate standard
1. clinical remission (in the recent period control): symptom and sign disappears, and lab testing recovers normally substantially, energy operate as normal and activity.
2. produce effects: symptom and sign disappears or significantly improves, and lab testing significantly improves or recovers normal, can participate in light work, the recovery general activity.
3. take a turn for the better: symptom and sign and lab testing make moderate progress.
4. invalid: clinical and lab testing improves not obvious or deterioration, death.
Four, clinical application method and therapeutic outcome
1, clinical application method
In that the patient is observed on the basis of condition of illness sign and laboratory examination, make a definite diagnosis.After being diagnosed as lupus erythematosus profundus, adopt the Chinese patent medicine of the oral embodiment of the invention usually, reach replenishing YIN and blood, wind-dispelling heat-dissipating, eliminating dampness and dredging channels; Clearing away heat-damp and promoting diuresis, promoting blood circulation to remove obstruction in the collateral; Removing pathogenic heat from blood and toxic substance from the body, disperse blood stasis and dredge collateral.Also can adopt the oral administration and externally used Therapeutic Method that combines for particular patients '.Wherein:
For oral administration: take the pill of embodiment 5, each 5-9 gram, every day 3-4 time, warm water delivery service, take half an hour ante cibum.Two months is a course for the treatment of, take continuously three the course for the treatment of observe the curative effect.
External: the medicine that proportioning is good, put into container and be heated to boiling 30 minutes, insulation then, it is stifling or embathe affected part that affected part is put container top, once a day, each 30 minutes.Or the medication water logging washes affected part,
2. clinical therapeutic efficacy
The inventor accepted lupus erythematosus profundus patient 16 examples for medical treatment altogether in 2,007 one 2010 4 years, male's 6 examples, and women's 10 examples, the age is 16-55 year.Clinical remission 3 examples account for 18.7% among the 16 routine patients, and produce effects 6 examples account for 37.5%, and effective 5 examples account for 31.3%, and invalid 2 examples account for 12.5%, and total effective rate reaches 87.5%.Clinical symptoms obviously alleviates, big recovery of function, and patient do not have any untoward reaction, three big routine tests and hepatic and renal function and internal organs infringement symptom detect do not find any unusual.Fully recover through the patient and to pay a return visit statistics, do not see an example recurrence so far.
The specific embodiment
Embodiment 1
Press the row weight portion and take by weighing each Chinese crude drug: 20 parts of Radix Polygoni Multiflori, 15 parts of Radix Paeoniae Rubra, 15 parts of Cortex Moutans, 15 parts of Radix Achyranthis Bidentataes, 20 parts of Fructus Corni, 20 parts of Herba Violaes, 20 parts of Radix Codonopsis, 15 parts of Cortex Cinnamomis, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 15 parts of Fructus Lycii, 15 parts of Radix Scutellariaes, 10 parts of the Cortexs Eucommiae, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Anemarrhenae skins, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Cornu Saigae Tataricae, 10 parts in Herba Spirodelae, 10 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made sublimed preparation according to the pharmaceutical methods that routine prepares sublimed preparation.
Embodiment 2
Press the row weight portion and take by weighing each medical material: 30 parts of Radix Polygoni Multiflori, 25 parts of Radix Paeoniae Rubra, 25 parts of Cortex Moutans, 25 parts of Radix Achyranthis Bidentataes, 30 parts of Fructus Corni, 30 parts of Herba Violaes, 30 parts of Radix Codonopsis, 25 parts of Cortex Cinnamomis, 25 parts of Radix Angelicae Sinensis, 25 parts of the Radix Paeoniae Albas, 25 parts of Fructus Lycii, 25 parts of Radix Scutellariaes, 15 parts of the Cortexs Eucommiae, 25 parts of Radix Arnebiae (Radix Lithospermi)s, 16 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Anemarrhenae skins, 15 parts of Radix Sophorae Flavescentiss, 20 parts of Cornu Saigae Tataricae, 20 parts in Herba Spirodelae, 20 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made packed powder according to the pharmaceutical methods that routine prepares powder.
Embodiment 3
Press the row weight portion and take by weighing each medical material: 22 parts of Radix Polygoni Multiflori, 18 parts of Radix Paeoniae Rubra, 18 parts of Cortex Moutans, 18 parts of Radix Achyranthis Bidentataes, 22 parts of Fructus Corni, 22 parts of Herba Violaes, 22 parts of Radix Codonopsis, 18 parts of Cortex Cinnamomis, 18 parts of Radix Angelicae Sinensis, 18 parts of the Radix Paeoniae Albas, 18 parts of Fructus Lycii, 18 parts of Radix Scutellariaes, 11 parts of the Cortexs Eucommiae, 18 parts of Radix Arnebiae (Radix Lithospermi)s, 11 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Anemarrhenae skins, 11 parts of Radix Sophorae Flavescentiss, 12 parts of Cornu Saigae Tataricae, 12 parts in Herba Spirodelae, 12 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made capsule according to the pharmaceutical methods that routine prepares capsule.
Embodiment 4
Press the row weight portion and take by weighing each medical material: 28 parts of Radix Polygoni Multiflori, 22 parts of Radix Paeoniae Rubra, 22 parts of Cortex Moutans, 22 parts of Radix Achyranthis Bidentataes, 28 parts of Fructus Corni, 28 parts of Herba Violaes, 28 parts of Radix Codonopsis, 22 parts of Cortex Cinnamomis, 22 parts of Radix Angelicae Sinensis, 22 parts of the Radix Paeoniae Albas, 22 parts of Fructus Lycii, 22 parts of Radix Scutellariaes, 14 parts of the Cortexs Eucommiae, 22 parts of Radix Arnebiae (Radix Lithospermi)s, 14 parts of Radix Salviae Miltiorrhizaes, 13 parts of Rhizoma Anemarrhenae skins, 14 parts of Radix Sophorae Flavescentiss, 18 parts of Cornu Saigae Tataricae, 18 parts in Herba Spirodelae, 18 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made tablet according to the pharmaceutical methods that routine prepares tablet, (as conventional tablet, sugar coated tablet, film coated tablet etc.), and give conventional drug excipient (as starch, sucrose, lactose, calcium stearate, magnesium stearate etc.).
Embodiment 5
Press the row weight portion and take by weighing each medical material: 25 parts of Radix Polygoni Multiflori, 20 parts of Radix Paeoniae Rubra, 20 parts of Cortex Moutans, 20 parts of Radix Achyranthis Bidentataes, 25 parts of Fructus Corni, 25 parts of Herba Violaes, 25 parts of Radix Codonopsis, 20 parts of Cortex Cinnamomis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 20 parts of Fructus Lycii, 20 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Anemarrhenae skins, 12 parts of Radix Sophorae Flavescentiss, 15 parts of Cornu Saigae Tataricae, 15 parts in Herba Spirodelae, 15 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made pill according to the pharmaceutical methods that routine prepares pill, and give conventional drug excipient.
Embodiment 6
Press the row weight portion and take by weighing each medical material: 23 parts of Radix Polygoni Multiflori, 18 parts of Radix Paeoniae Rubra, 18 parts of Cortex Moutans, 18 parts of Radix Achyranthis Bidentataes, 23 parts of Fructus Corni, 23 parts of Herba Violaes, 23 parts of Radix Codonopsis, 18 parts of Cortex Cinnamomis, 18 parts of Radix Angelicae Sinensis, 18 parts of the Radix Paeoniae Albas, 20 parts of Fructus Lycii, 20 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Anemarrhenae skins, 12 parts of Radix Sophorae Flavescentiss, 15 parts of Cornu Saigae Tataricae, 15 parts in Herba Spirodelae, 15 parts of Rhizoma Alismatis.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made granule according to the pharmaceutical methods that routine prepares granule.

Claims (5)

1. a Chinese patent medicine for the treatment of lupus erythematosus profundus is characterized in that being prepared from by following medicaments in part by weight: Radix Polygoni Multiflori 20-30 part, Radix Paeoniae Rubra 15-25 part, Cortex Moutan 15-25 part, Radix Achyranthis Bidentatae 15-25 part, Fructus Corni 20-30 part, Herba Violae 20-30 part, Radix Codonopsis 20-30 part, Cortex Cinnamomi 15-25 part, Radix Angelicae Sinensis 15-25 part, Radix Paeoniae Alba 15-25 part, Fructus Lycii 15-25 part, Radix Scutellariae 15-25 part, Cortex Eucommiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Radix Salviae Miltiorrhizae 9-16 part, Rhizoma Anemarrhenae skin 10-15 part, Radix Sophorae Flavescentis 10-15 part, Cornu Saigae Tataricae 10-20 part, Herba Spirodelae 10-20 part, Rhizoma Alismatis 10-20 part.
2. the Chinese patent medicine for the treatment of lupus erythematosus profundus according to claim 1 is characterized in that being prepared from by following medicaments in part by weight: Radix Polygoni Multiflori 22-28 part, Radix Paeoniae Rubra 18-22 part, Cortex Moutan 18-22 part, Radix Achyranthis Bidentatae 18-22 part, Fructus Corni 22-28 part, Herba Violae 22-28 part, Radix Codonopsis 22-28 part, Cortex Cinnamomi 18-22 part, Radix Angelicae Sinensis 18-22 part, Radix Paeoniae Alba 18-22 part, Fructus Lycii 18-22 part, Radix Scutellariae 18-22 part, Cortex Eucommiae 11-14 part, Radix Arnebiae (Radix Lithospermi) 18-22 part, Radix Salviae Miltiorrhizae 11-14 part, Rhizoma Anemarrhenae skin 12-13 part, Radix Sophorae Flavescentis 11-14 part, Cornu Saigae Tataricae 12-18 part, Herba Spirodelae 12-18 part, Rhizoma Alismatis 12-18 part.
3. the Chinese patent medicine for the treatment of lupus erythematosus profundus according to claim 1 is characterized in that being prepared from by following medicaments in part by weight: 25 parts of Radix Polygoni Multiflori, 20 parts of Radix Paeoniae Rubra, 20 parts of Cortex Moutans, 20 parts of Radix Achyranthis Bidentataes, 25 parts of Fructus Corni, 25 parts of Herba Violaes, 25 parts of Radix Codonopsis, 20 parts of Cortex Cinnamomis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 20 parts of structure Fructus Lyciis, 20 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Anemarrhenae skins, 12 parts of Radix Sophorae Flavescentiss, 15 parts of Cornu Saigae Tataricae, 15 parts in Herba Spirodelae, 15 parts of Rhizoma Alismatis.
4. according to the Chinese patent medicine of the described treatment lupus erythematosus profundus of arbitrary claim in the claim 1 to 3, it is characterized in that described Chinese patent medicine makes pill, sublimed preparation, powder, tablet, unguentum, decoction and the different oral medicine dosage form of capsule dress powder according to the conventional technology of preparing of Chinese medicine.
5. the Chinese patent medicine for the treatment of lupus erythematosus profundus according to claim 4 is characterized in that described Chinese patent medicine also contains drug excipient.
CN2011101698568A 2011-06-15 2011-06-15 Chinese prepared medicine for treating deep lupus erythematosus Active CN102362957B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101675960A (en) * 2008-09-18 2010-03-24 天津市中宝制药有限公司 Lupus II traditional Chinese medicine composition
CN101843718A (en) * 2009-10-22 2010-09-29 北京绿源求证科技发展有限责任公司 Chinese medicament for treating lupus erythematosus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101675960A (en) * 2008-09-18 2010-03-24 天津市中宝制药有限公司 Lupus II traditional Chinese medicine composition
CN101843718A (en) * 2009-10-22 2010-09-29 北京绿源求证科技发展有限责任公司 Chinese medicament for treating lupus erythematosus

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
温丽.红斑狼疮的饮食调护.《国际医药卫生导报》.2006,第12卷(第9期),70.
红斑狼疮的饮食调护;温丽;《国际医药卫生导报》;20061231;第12卷(第9期);全文 *
赵永昶等.防风通圣散在皮肤病中的临床应用.《甘肃中医》.2010,第23卷(第6期),
防风通圣散在皮肤病中的临床应用;赵永昶等;《甘肃中医》;20101231;第23卷(第6期);全文 *

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