CN105878600A - Traditional Chinese medicine preparation for treating thyroid cancer and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating thyroid cancer and preparation method thereof Download PDF

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CN105878600A
CN105878600A CN201610334023.5A CN201610334023A CN105878600A CN 105878600 A CN105878600 A CN 105878600A CN 201610334023 A CN201610334023 A CN 201610334023A CN 105878600 A CN105878600 A CN 105878600A
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corylopsis sinensis
crude drug
root
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating thyroid cancer and a preparation method thereof. The preparation is prepared from the following main medicinal raw materials in parts by weight: 4-10 parts of codonopsis pilosula, 6-9 parts of curculigo capitulata, 4-13 parts of codonacanthus pauciflorus, 3-7 parts of fermented soybeans, 4-8 parts of franchet groundcherry persistent calyx or fruit, 5-10 parts of typhonium giganteum, 6-9 parts of hylomecon japonica, 5-11 parts of chamaenerion angustifolium, 10-15 parts of seaweed, 8-13 parts of lysimachia christinae hance, 6-12 parts of corylopsis sinensis hemsl, 4-8 parts of ainsliaea latifolia, 3-8 parts of tangerine pith and 7-12 parts of rubus alceaefolius. The traditional Chinese medicine preparation has a remarkable treatment effect, quick response and relapse prevention, has effects of tonifying middle warmer and qi, calming, strengthening spleen, promoting blood circulation to remove meridian obstruction, stimulating the circulation of the blood, relaxing the muscles and joints, softening hard masses, diminishing swelling, clearing heat, removing toxicity, eliminating stasis, dispelling wind, harmonizing stomach and promoting blood circulation to remove stasis, can be used for enhancing body immunity, inhibiting growth of cancer cells, quickly reducing lumps, alleviating pain of patients, stabilizing condition and prolonging the living period so as to achieve the effect clinical healing.

Description

The Chinese medicine preparation for the treatment of thyroid carcinoma and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine preparation treating thyroid carcinoma and preparation side Method.
Background technology
Thyroid carcinoma is modal thyroid malignancy, is derived from the malignant tumor of Thyroid follicular epithelial cell.First Shape adenocarcinoma early clinical manifestation is inconspicuous, and patient or household chance on cervical region thyroid with doctor has matter hard and rugged Block, many no conscious symptons, neck region lump is often asymmetry lump, and thyroid nodule lump can be gradually increased, on swallowing Lower activity, and trachea can be invaded and fix, lump easily earlier generates pressure symptom, as with hoarseness, hypopnea, swallowed Difficulty, or the local pressure symptom such as tenderness, during jugular vein pressurized, may occur in which the signs such as Ipsilateral venous engorgement and facial edema, for , such as Lung metastases and Bone tumour etc., even there is pathologisch Bruch in one of feature of thyroid carcinoma.
Application publication number CN 105327205 A(application number 201510872293.7) Chinese patent literature disclose one Kind treating the Chinese medicine preparation of thyroid carcinoma, the Chinese medicine preparation of this invention includes following raw material: Poria, Radix Codonopsis, Herba Taxilli, Lentinus Edodes, Semen Phaseoli, Cortex Mori, the Cortex Eucommiae, Caulis Akebiae, Lignum Dalbergiae Odoriferae, the Rhizoma Atractylodis Macrocephalae, Fructus Akebiae, Rhizoma Arisaematis (processed), Fructus Chaenomelis, Herba Agrimoniae, Semen Coicis, Radix Sanguisorbae, Rhizoma Cynanchi Stauntonii, half Bian Lian, Folium cordylines fruticosae, Herba Hedyotidis Diffusae, Indigo Naturalis, Cortex Cinnamomi, Radix Sophorae Tonkinensis, Radix Polygalae, Rhizoma Alismatis, Flos Lonicerae, Radix Notoginseng, Semen Persicae, Scolopendra, trachelospermum jasminoide Rattan.Application publication number CN 104398831 A(application number 201410757776.8) Chinese patent literature disclose one and control Treating the Chinese medicine formula of thyroid carcinoma, the raw material of Chinese medicine by following parts by weight is formulated: Fructus Gleditsia 12-15 part, Bulbus Fritillariae Uninbracteatae 10-13 Part, Pseudobulbus Cremastrae Seu Pleiones 12-15 part, Semen Vaccariae 12-18 part, Thallus Laminariae (Thallus Eckloniae) 10-12 part, Herba Xanthii grass 8-12 part, Herba Scutellariae Barbatae 10-13 part, spend in vain Herba Hedyotidis Diffusae 10-12 part, Radix Salviae Miltiorrhizae 12-18 part, Fructus Polygoni Orientalis 14-17 part, Concha Ostreae 13-16 part, Rhizoma Arisaematis 6-8 part, Radix Codonopsis 8-12 part, Radix Astragali 6-12 part and Radix Angelicae Dahuricae 8-10 part.Application publication number CN 105456670 A(application number 201510985277.9) China specially Profit document discloses a kind of Chinese medicine treating thyroid carcinoma, is made up of the raw material of Chinese medicine of following weight portion: artificial Calculus Bovis 35-46 Part, Folium Et Cacumen Murrayae 23-36 part, two female peaceful 22-28 parts, Radix Berberidis 18-26 part, Resina Toxicodendri 16-28 part, Radix Inulae 13-18 Part, Herba Adenosmae 12-17 part, halite 9-15 part, Herba Rabdosiae glaucocalycis 3-8 part, Herba Sarcandrae 3-6 part, Pericarpium Citri Reticulatae Viride 5-12 part, bavin 6-12 part recklessly.
Currently, western medical treatment thyroid carcinoma typically uses operative treatment and chemicotherapy, matching medication after postoperative and chemicotherapy, Need to take high amount of drug, and it is higher to recur probability.Although the Chinese medicine for the treatment of thyroid carcinoma has a variety of, but, it is still So there are two aspect deficiencies: one is that effect is obvious not, two is that the comparison that takes effect is slow.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of Chinese medicine preparation treating thyroid carcinoma and preparation Method.Therapeutic effect of the present invention is notable, instant effect, is difficult to recurrence, plays invigorating the spleen and replenishing QI, calm spleen invigorating, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons work altogether Network, softening the hard mass detumescent, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dispelling wind stomach function regulating, the effect of blood circulation promoting and blood stasis dispelling, it is possible to enhancing human body immunity function, suppression The growth of cancerous cell, rapid drop lump, control transfer, alleviate patient suffering, stablize the state of an illness, extend life cycle, reach clinical Cure.
The technical scheme is that
The Chinese medicine preparation for the treatment of thyroid carcinoma, takes off and states the primary raw material medicine of weight proportion and be prepared from: Radix Codonopsis 4-10, great Ye are celestial Thatch 6-9, campanilla grass 4-13, Semen Sojae Preparatum 3-7, Calyx seu Fructus physalis 4-8, Herba Typhonii gigantei 5-10, Radix Hylomeci japonicae 6-9, Herba Epilobii Angustifoii 5-11, Sargassum 10- 15, Herba Lysimachiae 8-13, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 6-12, Herba Ainsliaeae Latifoliae 4-8, Vascular aurantii 3-8, great Ye Serpentis bubble 7-12.
Treatment thyroid carcinoma Chinese medicine preparation, preferred scheme is, take off state weight proportion primary raw material medicine preparation and Become: Radix Codonopsis 5-8, great Ye Rhizoma Curculiginis 7-8, campanilla grass 6-10, Semen Sojae Preparatum 4-6, Calyx seu Fructus physalis 5-7, Herba Typhonii gigantei 7-9, Radix Hylomeci japonicae 7-8, red Chopsticks 7-10, Sargassum 11-13, Herba Lysimachiae 10-12, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 8-11, Herba Ainsliaeae Latifoliae 5-7, Vascular aurantii 4-6, great Ye Serpentis bubble 9-11.
The Chinese medicine preparation for the treatment of thyroid carcinoma, scheme more preferably is, takes off the primary raw material medicine system stating weight proportion For forming: Radix Codonopsis 7, great Ye Rhizoma Curculiginis 7.5, campanilla grass 8, Semen Sojae Preparatum 5, Calyx seu Fructus physalis 6, Herba Typhonii gigantei 8, Radix Hylomeci japonicae 7.5, Herba Epilobii Angustifoii 9, sea Algae 12, Herba Lysimachiae 11, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 10, Herba Ainsliaeae Latifoliae 6, Vascular aurantii 5, great Ye Serpentis bubble 10.
Present invention also offers and the Chinese medicine preparation of aforementioned therapies thyroid carcinoma is made pharmaceutically acceptable granule, dissipate The preparation method of agent, pill and capsule.
The preparation method of described granule is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, add the starch slurry that concentration is 12%-16% and (be preferably added to Concentration is the starch slurry of 14%), the amount of starch slurry is step (1), step (2) and the 1/5 of step (3) gained gross weight, makes soft Material, crosses 16-20 mesh sieve (preferably crossing 18 mesh sieves), makes granule, be dried, granulate, and packaging to obtain final product.
The preparation method of described powder is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, with 5g often bag subpackage, sterile packaged and get final product.
The preparation method of described pill is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, with the general ball of vinegar, make the pill that particle diameter is 3mm, subpackage, Obtain.
The preparation method of described capsule is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, add the starch slurry that concentration is 12%-16% and (be preferably added to Concentration is the starch slurry of 14%), the amount of starch slurry is step (1), step (2) and the 1/5 of step (3) gained gross weight, makes soft Material, crosses 20 mesh sieves, makes granule, is dried, and loads capsule, equipped with medicine 0.4g in every seed lac capsule, to obtain final product.
The Chinese medicine preparation scientific formula of the treatment thyroid carcinoma that the present invention provides, the preparation method of various dosage forms is simple, institute Obtain product taking convenience, be easy to carry.In addition, the excellent results of the present invention is also manifested by:
1, therapeutic effect is notable, instant effect, is difficult to recurrence；
2, have invigorating the spleen and replenishing QI, calm spleen invigorating, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons and activating QI and blood in the collateral, softening the hard mass detumescent, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling,
Dispelling wind stomach function regulating, the effect of blood circulation promoting and blood stasis dispelling, it is possible to enhancing human body immunity function, the growth of anticancer, rapid drop lump, Control transfer, alleviate patient suffering, stablize the state of an illness, extend life cycle, reach clinical cure.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 treats the Chinese medicine preparation of thyroid carcinoma, takes the primary raw material medicine of following weight parts and is prepared from that (every part is 600g): Radix Codonopsis 4 parts, great Ye Rhizoma Curculiginis 6 parts, campanilla grass 4 parts, Semen Sojae Preparatum 3 parts, Calyx seu Fructus physalis 4 parts, Herba Typhonii gigantei 5 parts, Radix Hylomeci japonicae 6 parts, Herba Epilobii Angustifoii 5 parts, Sargassum 10 parts, Herba Lysimachiae 8 parts, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 6 parts, Herba Ainsliaeae Latifoliae 4 parts, Vascular aurantii 3 parts, great Ye Serpentis steeps 7 parts.
The preparation method of the Chinese medicine preparation powder of above-mentioned treatment thyroid carcinoma is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The 1/7 of hemp nettle root three taste crude drug gross weight, moistening 25 minutes, slow fire stir-fries 12 minutes, takes out, dries, be ground into fine powder, mistake Sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50 DEG C, takes out, cools, be ground into fine powder, Sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6 times of 10 taste crude drug gross weights, decocts 1.5 hours every time, merges twice medicinal liquid, stands 12 Hour, upper liquid is condensed into the thick paste that relative density is 1.41, dry, pulverize into fine powder, sieve；
(4) step (1), step (2) and step (3) gained are mixed, with 5g often bag subpackage, sterile packaged and get final product.
The instructions of taking of the Chinese medicine preparation powder of gained of the present invention treatment thyroid carcinoma is: oral, twice on the one, every time 5g, boiled water is taken after mixing it with water.
Embodiment 2 treats the Chinese medicine preparation of thyroid carcinoma, takes the primary raw material medicine of following weight parts and is prepared from that (every part is 600g): Radix Codonopsis 10 parts, great Ye Rhizoma Curculiginis 9 parts, campanilla grass 13 parts, Semen Sojae Preparatum 7 parts, Calyx seu Fructus physalis 8 parts, Herba Typhonii gigantei 10 parts, Radix Hylomeci japonicae 9 Part, Herba Epilobii Angustifoii 11 parts, Sargassum 15 parts, Herba Lysimachiae 13 parts, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 12 parts, Herba Ainsliaeae Latifoliae 8 parts, Vascular aurantii 8 parts, great Ye Serpentis bubble 12 Part.
The preparation method of the Chinese medicine preparation granule of above-mentioned treatment thyroid carcinoma is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The 1/6 of hemp nettle root three taste crude drug gross weight, moistening 35 minutes, slow fire stir-fries 15 minutes, takes out, dries, be ground into fine powder, mistake Sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 60 DEG C, takes out, cools, be ground into fine powder, Sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 7 times of 10 taste crude drug gross weights, decocts 1.5 hours every time, merges twice medicinal liquid, stands 12 Hour, upper liquid is condensed into the thick paste that relative density is 1.44, dry, pulverize into fine powder, sieve；
(4) step (1), step (2) and step (3) gained being mixed, adding concentration is the starch slurry of 14%, and the amount of starch slurry is Step (1), step (2) and the 1/5 of step (3) gained gross weight, make soft material, crosses 18 mesh sieves, makes granule, is dried, granulate, Packaging, to obtain final product.
Model case one: old XX, female, 40 years old.Before more than 1 year, patient goes to a doctor in local hospital, in locality because of the right cervical region thing that swells Hospital's row thyroid B ultrasonic shows left lobe of thyroid gland multiple nodules, thyroid diffusivity pathological changes, and the bilateral thyroid that carries out cuts art, art entirely The return of rear pathology is right thyroid papillary carcinoma.Drug administration is treated, without being clearly better.Come here diagnosis and treatment.The right neck of patient Portion can lay one's hand on and goose egg size lump, edge finishing, and quality is hard, has tenderness, and the colour of skin is normal, can move up and down with swallowing, neck Vein not anger is opened, lymphonodi cervicales do not lay one's hand on and, tongue darker in color, white and greasy fur, slippery and rapid pulse.Take the present embodiment gained treatment first shape The Chinese medicine preparation granule of adenocarcinoma, three times on the one, each 12g, boiled water is taken after mixing it with water.Taking 1 month, neck region lump reduces.Take two Individual month, recovery from illness, follow up a case by regular visits to without recurrence.
Embodiment 3 treats the Chinese medicine preparation of thyroid carcinoma, takes the primary raw material medicine of following weight parts and is prepared from that (every part is 600g): Radix Codonopsis 5 parts, great Ye Rhizoma Curculiginis 7 parts, campanilla grass 6 parts, Semen Sojae Preparatum 4 parts, Calyx seu Fructus physalis 5 parts, Herba Typhonii gigantei 7 parts, Radix Hylomeci japonicae 7 parts, Herba Epilobii Angustifoii 7 parts, Sargassum 11 parts, Herba Lysimachiae 10 parts, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 8 parts, Herba Ainsliaeae Latifoliae 5 parts, Vascular aurantii 4 parts, great Ye Serpentis steeps 9 parts.
The preparation method of the Chinese medicine preparation pill of above-mentioned treatment thyroid carcinoma is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The 1/6 of hemp nettle root three taste crude drug gross weight, moistening 35 minutes, slow fire stir-fries 15 minutes, takes out, dries, be ground into fine powder, mistake Sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 60 DEG C, takes out, cools, be ground into fine powder, Sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 7 times of 10 taste crude drug gross weights, decocts 1.5 hours every time, merges twice medicinal liquid, stands 12 Hour, upper liquid is condensed into the thick paste that relative density is 1.44, dry, pulverize into fine powder, sieve；
(4) step (1), step (2) and step (3) gained are mixed, with the general ball of vinegar, make the pill that particle diameter is 3mm, subpackage, Obtain.
Model case two: XX recklessly, man, 58 years old.Before half a year is remaining, patient, because neck region lump is to examination in hospital, examines as thyroid Cancer.After treatment, effect is undesirable.Then here diagnosis and treatment.Take the Chinese medicine preparation pill of the present embodiment gained treatment thyroid carcinoma, Three times on the one, each 6 balls, warm water takes.Taking 1 month, Thyroid Tumors reduces.Take two months, recovery from illness, follow up a case by regular visits to without multiple Send out.
Embodiment 4 treats the Chinese medicine preparation of thyroid carcinoma, takes the primary raw material medicine of following weight parts and is prepared from that (every part is 600g): Radix Codonopsis 8 parts, great Ye Rhizoma Curculiginis 8 parts, campanilla grass 10 parts, Semen Sojae Preparatum 6 parts, Calyx seu Fructus physalis 7 parts, Herba Typhonii gigantei 9 parts, Radix Hylomeci japonicae 8 parts, Herba Epilobii Angustifoii 10 parts, Sargassum 13 parts, Herba Lysimachiae 12 parts, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 11 parts, Herba Ainsliaeae Latifoliae 7 parts, Vascular aurantii 6 parts, great Ye Serpentis steeps 11 parts.
The preparation method of the Traditional Chinese medicine preparation capsule agent of above-mentioned treatment thyroid carcinoma is:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The 1/6 of hemp nettle root three taste crude drug gross weight, moistening 35 minutes, slow fire stir-fries 15 minutes, takes out, dries, be ground into fine powder, mistake Sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 60 DEG C, takes out, cools, be ground into fine powder, Sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 7 times of 10 taste crude drug gross weights, decocts 1.5 hours every time, merges twice medicinal liquid, stands 12 Hour, upper liquid is condensed into the thick paste that relative density is 1.44, dry, pulverize into fine powder, sieve；
(4) step (1), step (2) and step (3) gained being mixed, adding concentration is the starch slurry of 14%, and the amount of starch slurry is Step (1), step (2) and the 1/5 of step (3) gained gross weight, make soft material, crosses 20 mesh sieves, makes granule, is dried, and loads Capsule, equipped with medicine 0.4g in every seed lac capsule, to obtain final product.
Model case three: Liu XX, female, 43 years old.Before more than 1 year, patient, because neck region lump is to examination in hospital, examines as thyroid Cancer.Row excision, postoperative recurs after radiotherapy repeatedly, then comes to go to a doctor.Examine and see that patient throat goiter protuberantia quality is hard, relatively It is fixing, shape such as inflammatory blepharoedema, sometimes swell and have a pain, chest distress, cough with copious phlegm or both sides, throat scrofula grow thickly, appetite stimulator, and two The most uncomfortable, body of the tongue is livid purple, thick and greasy fur, stringy and rolling pulse.Take the present embodiment gained treatment thyroid carcinoma Traditional Chinese medicine preparation capsule agent, one Day three times, each 3, warm water takes.Taking 1 month, neck region lump reduces.Take two months, recovery from illness, follow up a case by regular visits to without recurrence.
Embodiment 5 treats the Chinese medicine preparation of thyroid carcinoma, takes the primary raw material medicine of following weight parts and is prepared from that (every part is 600g): Radix Codonopsis 7 parts, great Ye Rhizoma Curculiginis 7.5 parts, campanilla grass 8 parts, Semen Sojae Preparatum 5 parts, Calyx seu Fructus physalis 6 parts, Herba Typhonii gigantei 8 parts, Radix Hylomeci japonicae 7.5 Part, Herba Epilobii Angustifoii 9 parts, Sargassum 12 parts, Herba Lysimachiae 11 parts, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 10 parts, Herba Ainsliaeae Latifoliae 6 parts, Vascular aurantii 5 parts, great Ye Serpentis steeps 10 parts.
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae With the 1/6 of Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste crude drug gross weight, moistening 35 minutes, slow fire stir-fries 15 minutes, takes out, dries, and is ground into thin Powder, sieves；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 60 DEG C, takes out, cools, be ground into fine powder, Sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 7 times of 10 taste crude drug gross weights, decocts 1.5 hours every time, merges twice medicinal liquid, stands 12 Hour, upper liquid is condensed into the thick paste that relative density is 1.44, dry, pulverize into fine powder, sieve；
(4) step (1), step (2) and step (3) gained are mixed, with 5g often bag subpackage, sterile packaged and get final product.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
Radix Codonopsis: base: for Campanulaceae Radix Codonopsis, the dry root of element flower Radix Codonopsis or radix codonpsis tangshen etc..The property of medicine: sweet, flat.Return spleen, lung Warp.Function cures mainly: invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat disappears Yearningly.
Great Ye Rhizoma Curculiginis: base: Hypoxidaceae Curculigo great Ye Rhizoma Curculiginis, is used as medicine with root and root stock.The property of medicine: bitter, puckery, Flat.Function cures mainly: moistening the lung and resolving phlegm, relieving cough and asthma, calm spleen invigorating, tonifying the kidney to consolidate the essence.For dyspnea and cough due to deficiency of the kidney, soreness of waist and knee joint, leucorrhea, lose Essence.
Campanilla grass: base: for the herb of acanthaceous plant campanilla grass.The property of medicine: bitter in the mouth；Micro-pungent；Cool in nature.Function cures mainly: clear Heart-fire；Promoting blood circulation to remove obstruction in the collateral.Main aphtha of the mouth and tongue；Rheumatic arthralgia；Traumatic injury.
Semen Sojae Preparatum: base: the mature seed for the black of legume soybean processes through steaming net for catching birds or fish fermentation etc..The property of medicine: Bitter, pungent, flat.Return lung, stomach, the heart, bladder, small intestinal, tri-jiao channel.Function cures mainly: expelling pathogenic factors from muscles is delivered, and declares strongly fragrant relieving restlessness.Main diseases caused by exogenous pathogenic factor exterior syndrome, cold Heat headache, vexed, uncomfortable in chest.
Calyx seu Fructus physalis: base: for the fruit of the band Constellation calyx of plant of Solanaceae Calyx seu Fructus physalis and Calyx seu fructus physalis.The property of medicine: sour in the mouth；Sweet；Cold in nature.Return Lung, kidney channel.Function cures mainly: removing heat from the lung and relieving sorethroat, changes dysentery diuretic.Main lung-heat productive cough, laryngopharynx swelling and pain, hectic fever due to YIN-deficiency consumptive fever, urine leaching is puckery, sky bleb Eczema.
Herba Typhonii gigantei: base: for the herb of aroid Herba Typhonii gigantei.Function cures mainly: control venom, scrofula, traumatic injury Damage.
Radix Hylomeci japonicae: base: for the root of bloodroot Radix Hylomeci japonicae.The property of medicine: " Shaanxi Chinese herbal medicine ": " bitter in the mouth, property is put down." function Cure mainly: " Shaanxi Chinese herbal medicine ": " wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, dissipating blood stasis for subsidence of swelling, analgesic hemostatic.Treating rheumatic arthritis, impairment caused by overstrain, traumatic injury Damage.”
Herba Epilobii Angustifoii: base: for the herb of onagraceae plant willow herb.The property of medicine: bitter in the mouth；Property flat.Function cures mainly: promoting diuresis to eliminate damp pathogen, reason Gas relieving distension, promoting blood flow to regulate menstruation.Main edema, has loose bowels, food stagnation distension, menoxenia, galactostasis, scrotum enlargement, and skin ulcer rash is itched bitterly.
Sargassum: base: for Sargassaceae plant Sargassum fusiforme (Harv.) Setch and the frond of Sargassum.The property of medicine: bitter, salty, cold.Return lung, spleen, Kidney, liver stomach warp.Function cures mainly: softening the hard mass, expectorant, diuretic, detumescent.Main scrofula, goiter, accumulation, edema, tinea pedis, painful and swollen testis, (Epileptic is ruined) hernia.
Herba Lysimachiae: base: for the herb of Ofthe Primulaceae Lysimachia christinae Hance.The property of medicine: hardship sweet, micro-, cool.Return liver, gallbladder, kidney, wing Guang warp.Function cures mainly: relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Main liver and gall and urinary system calculus, pyretic stranguria, oedema due to nephritis is wet Hot jaundice, sore carbuncle, venom, traumatic injury.
Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root: base: for root or the root bark of Hamamelidaceae Plants China Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．).The property of medicine: sweet；Flat.Return stomach, the heart Warp.Function cures mainly: dispelling wind stomach function regulating, mind tranquilizing and the heart calming.Main diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, headache, nausea and vomiting, cardiopalmus, dysphoria.
Herba Ainsliaeae Latifoliae: base: for the herb of feverfew width fringe Ainsliaea fragrans Champ..The property of medicine: acrid in the mouth；Micro-hardship；Warm in nature.Function cures mainly: Expelling wind and cold, promoting blood circulation and detumescence.Main anemofrigid cold, headache, lumbago, intestinal fire, dysentery, traumatic injury congestive edema, traumatic hemorrhage, otitis media, breast Adenitis.
Vascular aurantii: base: for the grain in the peel of rutaceae orange.The property of medicine: bitter, flat.Function cures mainly: dredging collateral, reduces phlegm. For cough with copious phlegm, the breast side of body is had a pain.
Great Ye She Pao: base: the root of Rosaceae rubus Radix seu Folium Rubi alceaefolii and leaf.The property of medicine: sweet, light, flat.Merit With curing mainly: clearing away heat-damp and promoting diuresis, activating blood and removing stasis.For hepatitis, hepatosplenomegaly, stomatitis, mastitis, dysentery, enteritis, traumatic injury, Rheumatic ostalgia；Traumatic hemorrhage is controlled in external.
The clinical practice of the Chinese medicine preparation (embodiment 5) of test example 1 gained of the present invention treatment thyroid carcinoma: in March, 2011- In June, 2013, screen 260 example thyroid cancer patients in 3 hospitals.Being randomly divided into two groups, experimental group and matched group (often organize 130 Example).Between two groups of patients, the aspect such as sex, age, course of disease compares, and no significant difference (P ＞ 0.05) has comparable Property.
Therapeutic Method: experimental group uses the Chinese medicine preparation of gained of the present invention treatment thyroid carcinoma, and using method is: oral, Twice on the one, each 5g, boiled water is taken after mixing it with water.Matched group uses the medicines such as compound recipe cantharidin capsule, XIAOAIPING PIAN, ginseng pellet eliminating stagnation capsule to control Treat.Two groups of patients carry out comparitive study after all treating 2 months.
Curative effect judging standard: cure: throat lump, clinical symptom disappearance, pathological biopsy cancer-free cell finds；Take a turn for the better: neck Front mass reduction, clinical symptom relief；Invalid: throat lump does not reduces, clinical symptoms is without improving.
Table 1: the Chinese medicine preparation compliance test result of gained of the present invention treatment thyroid carcinoma
Efficacy analysis: experimental group cures 59 examples, take a turn for the better 68 examples, invalid 3 examples, total effective rate 97.69%；Matched group cures 12 examples, good Turn 76 examples, invalid 42 examples, total effective rate 67.69%.The cure rate of experimental group and total effective rate are apparently higher than matched group.Test table Bright, the clinical efficacy of experimental group is substantially better than matched group, significant difference (P ＜ 0.05), has statistical significance.
The present invention, with Radix Codonopsis, great Ye Rhizoma Curculiginis, campanilla grass and Semen Sojae Preparatum etc. as primary raw material, makes in treatment thyroid carcinoma Medicine preparation.Radix Codonopsis invigorating the spleen and replenishing QI in side, strengthening spleen and tonifying lung.Great Ye Rhizoma Curculiginis moistening the lung and resolving phlegm, relieving cough and asthma, calm spleen invigorating, tonifying the kidney to consolidate the essence. Campanilla grass clearing away heart-fire；Promoting blood circulation to remove obstruction in the collateral.Semen Sojae Preparatum expelling pathogenic factors from muscles is delivered, and declares strongly fragrant relieving restlessness.Calyx seu Fructus physalis removing heat from the lung and relieving sorethroat, changes dysentery diuretic.Herba Typhonii gigantei Control venom, scrofula, traumatic injury.Radix Hylomeci japonicae wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, dissipating blood stasis for subsidence of swelling, analgesic hemostatic.Herba Epilobii Angustifoii diuretic oozes Wet, relieving distension of regulating the flow of vital energy, promoting blood flow to regulate menstruation.Sargassum softening the hard mass, expectorant, diuretic, detumescent.Herba Lysimachiae relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis disappears Swollen.Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root dispelling wind stomach function regulating, mind tranquilizing and the heart calming.Herba Ainsliaeae Latifoliae expelling wind and cold, promoting blood circulation and detumescence.Vascular aurantii dredging collateral, reduces phlegm.Great Ye She Pao Clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling.All medicines share, play altogether invigorating the spleen and replenishing QI, calm spleen invigorating, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons and activating QI and blood in the collateral, softening the hard mass detumescent, Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dispelling wind stomach function regulating, the effect of blood circulation promoting and blood stasis dispelling, it is possible to enhancing human body immunity function, the life of anticancer Long, rapid drop lump, control transfer, alleviate patient suffering, stablize the state of an illness, extend life cycle, reach clinical cure.
Finally it should be noted that embodiment is the optimum detailed description of the invention of the present invention, be not limited to this Invention, although being described in detail the present invention with reference to previous embodiment, for a person skilled in the art, it depends on So the technical scheme described in foregoing embodiments can be modified, or wherein portion of techniques feature is carried out equivalent replace Change.All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included in the present invention Protection domain within.

Claims (10)

1. treat the Chinese medicine preparation of thyroid carcinoma, it is characterised in that take off and state the primary raw material medicine of weight proportion and be prepared from: party Ginseng 4-10, great Ye Rhizoma Curculiginis 6-9, campanilla grass 4-13, Semen Sojae Preparatum 3-7, Calyx seu Fructus physalis 4-8, Herba Typhonii gigantei 5-10, Radix Hylomeci japonicae 6-9, Herba Epilobii Angustifoii 5-11, Sargassum 10-15, Herba Lysimachiae 8-13, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 6-12, Herba Ainsliaeae Latifoliae 4-8, Vascular aurantii 3-8, great Ye Serpentis bubble 7-12.
2. the Chinese medicine preparation treating thyroid carcinoma as claimed in claim 1, it is characterised in that take off and state the main of weight proportion Crude drug is prepared from: Radix Codonopsis 5-8, great Ye Rhizoma Curculiginis 7-8, campanilla grass 6-10, Semen Sojae Preparatum 4-6, Calyx seu Fructus physalis 5-7, Herba Typhonii gigantei 7-9, Radix Hylomeci japonicae 7-8, Herba Epilobii Angustifoii 7-10, Sargassum 11-13, Herba Lysimachiae 10-12, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 8-11, Herba Ainsliaeae Latifoliae 5-7, Vascular aurantii 4-6, greatly Leaf Serpentis bubble 9-11.
3. the Chinese medicine preparation treating thyroid carcinoma as claimed in claim 1, it is characterised in that take off and state the main of weight proportion Crude drug is prepared from: Radix Codonopsis 7, great Ye Rhizoma Curculiginis 7.5, campanilla grass 8, Semen Sojae Preparatum 5, Calyx seu Fructus physalis 6, Herba Typhonii gigantei 8, and Radix Hylomeci japonicae 7.5 is red Chopsticks 9, Sargassum 12, Herba Lysimachiae 11, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root 10, Herba Ainsliaeae Latifoliae 6, Vascular aurantii 5, great Ye Serpentis bubble 10.
4. the preparation method of the Chinese medicine preparation granule of the treatment thyroid carcinoma as described in claims 1 to 3 is arbitrary, its feature exists In, step is as follows:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, add the starch slurry that concentration is 12%-16% and (be preferably added to Concentration is the starch slurry of 14%), the amount of starch slurry is step (1), step (2) and the 1/5 of step (3) gained gross weight, makes soft Material, crosses 16-20 mesh sieve (preferably crossing 18 mesh sieves), makes granule, be dried, granulate, and packaging to obtain final product.
5. the preparation method of the Chinese medicine preparation powder of the treatment thyroid carcinoma as described in claims 1 to 3 is arbitrary, its feature exists In, step is as follows:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The 1/7-1/5 of hemp nettle root three taste crude drug gross weight, moistening 25-40 minute, slow fire stir-fries 12-16 minute, takes out, dries, powder It is broken into fine powder, sieves；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, with 5g often bag subpackage, sterile packaged and get final product.
6. the preparation method of the Chinese medicine preparation pill of the treatment thyroid carcinoma as described in claims 1 to 3 is arbitrary, its feature exists In, step is as follows:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, with the general ball of vinegar, make the pill that particle diameter is 3mm, subpackage, Obtain.
7. the preparation method of the Traditional Chinese medicine preparation capsule agent of the treatment thyroid carcinoma as described in claims 1 to 3 is arbitrary, its feature exists In, step is as follows:
(1) taking great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, add barley wine, the amount of barley wine is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and wax The amount of the preferred barley wine of 1/7-1/5(of hemp nettle root three taste crude drug gross weight is great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root three taste The 1/6 of crude drug gross weight), moistening 25-40 minute (preferably moistening 35 minutes), slow fire stir-fries 12-16 minute, and (preferably slow fire turns over Fry 15 minutes), take out, dry, be ground into fine powder, sieve；
(2) taking Sargassum, be soaked in water 3 days, every day changes water twice, is dried 12 hours in 50-70 DEG C and (is preferable over 60 DEG C and is dried 12 little Time), take out, cool, be ground into fine powder, sieve；
(3) remaining the 10 taste crude drug in addition to great Ye Rhizoma Curculiginis, Radix Hylomeci japonicae, Sargassum and Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root are put in pot, boiling Twice, each amount of water is 6-8 times of 10 taste crude drug gross weights, and (amount of water is 10 taste crude drug gross weights preferably every time 7 times), decoct 1.5 hours every time, merge twice medicinal liquid, stand 12 hours, it is 1.41-that upper liquid is condensed into relative density The thick paste (upper liquid is preferably condensed into the thick paste that relative density is 1.44) of 1.45, dry, pulverize into fine powder, sieves；
(4) step (1), step (2) and step (3) gained are mixed, add the starch slurry that concentration is 12%-16% and (be preferably added to Concentration is the starch slurry of 14%), the amount of starch slurry is step (1), step (2) and the 1/5 of step (3) gained gross weight, makes soft Material, crosses 20 mesh sieves, makes granule, is dried, and loads capsule, equipped with medicine 0.4g in every seed lac capsule, to obtain final product.
8. the preparation method of the Chinese medicine preparation powder for the treatment of thyroid carcinoma as claimed in claim 5, it is characterised in that step (1) amount of barley wine is great Ye Rhizoma Curculiginis, Cortex corylopsis sinensis radicis (Corylopsis sinensis Hemsl．) root, Radix Hylomeci japonicae and the 1/6 of Radix Cynanchi Atrati four taste crude drug gross weight.
9. the preparation method of the Chinese medicine preparation powder for the treatment of thyroid carcinoma as claimed in claim 5, it is characterised in that step (1) moistening 35 minutes.
10. the preparation method of the Chinese medicine preparation powder for the treatment of thyroid carcinoma as claimed in claim 5, it is characterised in that step (1) slow fire stir-fries 15 minutes.
CN201610334023.5A 2016-05-19 2016-05-19 Traditional Chinese medicine preparation for treating thyroid cancer and preparation method thereof Withdrawn CN105878600A (en)

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CN114246918B (en) * 2021-12-16 2022-10-14 浙江省人民医院 Traditional Chinese medicine composition for treating hashimoto thyroiditis and preparation method thereof

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