CN104694315B - A kind of anti-aging grape wine and preparation method - Google Patents

A kind of anti-aging grape wine and preparation method Download PDF

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CN104694315B
CN104694315B CN201510125446.1A CN201510125446A CN104694315B CN 104694315 B CN104694315 B CN 104694315B CN 201510125446 A CN201510125446 A CN 201510125446A CN 104694315 B CN104694315 B CN 104694315B
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wine
grape
fruit
grape wine
fermentation
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CN104694315A (en
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王栩
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Hubei Chang'e Biological Co ltd
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Qingdao Jinzhi High And New Technology Co Ltd
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Priority to CN201610500682.1A priority Critical patent/CN106118944A/en
Priority to CN201610496589.8A priority patent/CN106085681A/en
Priority to CN201510125446.1A priority patent/CN104694315B/en
Priority to CN201610497001.0A priority patent/CN105936851A/en
Priority to CN201610496617.6A priority patent/CN105936847A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G1/00Preparation of wine or sparkling wine
    • C12G1/02Preparation of must from grapes; Must treatment and fermentation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G1/00Preparation of wine or sparkling wine
    • C12G1/02Preparation of must from grapes; Must treatment and fermentation
    • C12G1/0203Preparation of must from grapes; Must treatment and fermentation by microbiological or enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine

Abstract

The invention discloses a kind of anti-aging grape wine, following raw materials according be prepared from, be weight portion: mulberries 36 48;Grape pip 10 16;The fruit of Chinese wolfberry 21 34;The fruit of Chinese magnoliavine 18 26;Barrenwort 19 28;Pollen 5 10;Grape wine 325 528.The excellent results of the present invention is also manifested by: grape wine aromatic taste of the present invention, has beneficial gas bowl spares, effects such as intelligence development of allaying excitement, and has multiple nutrients value, moreover it is possible to fundamentally effectively regulates patient body, improve fitness;Grape wine of the present invention contains more anti-oxidant composition, can eliminate or to antioxidant radical such as phenolate thing, Flavonoid substances, trace element etc., reach the effect of anti-ageing diseases prevention.

Description

A kind of anti-aging grape wine and preparation method
Technical field
The present invention relates to a kind of grape wine, particularly relate to a kind of anti-aging grape wine and preparation method.
Background technology
Grape wine is with its abundant nutrition and health care value, and there be good popularizing and popularization in a lot of countries in the world.In recent years, along with the growth of China's economy, the raising of per capita income level and the enhancing of health care consciousness, the wine industry of China develops rapidly, and the benefit drinking grape wine the most increasingly obtains the accreditation of compatriots, becomes daily popular beverage wine product.
Due to existence and the local flavor of grape wine deliciousness of organic and inorganic materials various in grape wine, it is made not only to become a kind of nutritious beverage, and under conditions of drinking in right amount, moreover it is possible to prevent and treat various disease, strengthen health.The effect of grape wine is as follows: 1, sedation: nervimotion maincenter can be worked by grape wine, gives comfortable, glad sensation.2, digestion-aid effect: grape wine CNOOC potassium sorbate, contributes to the secretion of bile and pancreas, can help digest, and prevents treating constipation.3, the effect of anti-angiocardiopathy: the preventing and treating of cardiovascular disease is played an important role by the proanthocyanidin in grape wine, in ductus arteriosus wall, proanthocyanidin can stably constitute the collagenous fibres of various film, histidine decarboxylase can be suppressed, avoid producing the too much group ammonia that can reduce the saturating property of tube wall, prevent artery sclerosis.
Application publication number CN 103710193 A(application number 201210369290.8) Chinese invention patent document discloses a kind of health wine, and composition of raw materials is: grape juice 1000-1200 gram, glossy ganoderma 0.4-0.5 gram, ginseng 0.8-1.0 gram, beautiful 4-5 gram of cassia bark, matrimony vine 8-10 gram, Niu great Li 0.5-0.8 gram, 20-25 gram of Radix Glycyrrhizae.Application publication number CN 104212674 A(application number 201410457438.2) Chinese invention patent document discloses a kind of grape wine, is made up of the raw material of following weight portion: fresh grape 81-89 part, fruit of Chinese magnoliavine 2-3 part, honey 3-5 part, yeast 3-5 part, white granulated sugar 2-3 part, Momordica grosvenori 1-3 part.Application publication number CN 102051291 A(application number 200910188307.8) Chinese invention patent document disclose a kind of wolfberry wine, it is prepared from by the raw material of following weight: fruit of Chinese wolfberry 1000g, ginseng 40g, sheep leaves of pulse plants 60g, deer pallet 20g, tag 20g, Radix Glycyrrhizae 20g, Chinese cassia tree 40g, saline cistanche 40g, reticulate millettia 120g, Radix Angelicae Sinensis 120g, actinolite 120g, grape juice 140kg.
Grape wine in the market mostly is vin ordinaire, and composition is more single, although nutritive value is higher, but the limited efficacy such as anti-aging, beauty treatment.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide one and prepare simply, take safety, a kind of anti-aging grape wine of effect and preparation method.Grape wine of the present invention is nutritious, inexpensive, is suitable for drinking for a long time.
The technical scheme is that
A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion: mulberries 36-48;Grape pip 10-16;Fruit of Chinese wolfberry 21-34;Fruit of Chinese magnoliavine 18-26;Barrenwort 19-28;Pollen 5-10;Grape wine 325-528.
Preferably in scheme, mulberries 40-44;Grape pip 12-14;Fruit of Chinese wolfberry 25-30;Fruit of Chinese magnoliavine 20-24;Barrenwort 22-25;Pollen 7-8;Grape wine 365-488.
More preferably, mulberries 42;Grape pip 13;The fruit of Chinese wolfberry 27.5;The fruit of Chinese magnoliavine 22;Barrenwort 23.5;Pollen 7.5;Grape wine 426.5.
A kind of anti-aging preparation of wine, step is as follows:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, add 90 DEG C of deionized waters of 8-12 times amount, extract twice, the most each extraction 58-76 minute (preferably every time respectively extracting 67 minutes), filter, merge extract, it is evaporated to the 1/3 of original volume, then it is centrifuged 10-16 minute (being preferably centrifuged 13 minutes with the rotating speed of 5000r/min) with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take grape juice to be placed in fermentation tank, the mulberries after the yeast of 0.015 times of grape juice amount of addition and step (1) process, seal, shake up, cold fermentation 6-10 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds pollen and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 10-20 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, adds the deionized water (preferably adding the deionized water of 10 times amount) of 9-11 times amount in step (1).
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, in step (2), grape juice is cabernet sauvignon grape juice.
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, in step (2), the temperature of cold fermentation is 18-26 DEG C (temperature of preferred cold fermentation is 20-24 DEG C, and the temperature of cold fermentation more preferably is 22 DEG C).
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, cold fermentation 7-9 days (preferably cold fermentation 8 days) in step (2).
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, in step (3), added pollen is the one in Flos Rosae Rugosas pollen, pollen powder of sweet osmanthus and chrysanthemum powder.
The anti-aging preparation of wine of above-mentioned one, preferred scheme is, step (3) relaying supervention ferment 13-17 days (preferably continuing to ferment 15 days).
Grape wine scientific formula of the present invention, preparation method is simple, nutritious, safe and effective.In addition, the excellent results of the present invention is also manifested by:
1 Grape wine aromatic taste of the present invention, has beneficial gas bowl spares, effects such as intelligence development of allaying excitement, and has multiple nutrients value, moreover it is possible to fundamentally effectively regulate patient body, improve fitness;
2 Grape wine of the present invention contains more anti-oxidant composition, can eliminate or to antioxidant radical such as phenolate thing, Flavonoid substances, trace element etc., reach the effect of anti-ageing diseases prevention;
3 Grape wine of the present invention can make that user is in high spirits, delays senility, effect is notable, has no side effect, and special standby be suitable for the elderly and take.
Effect of primary raw material used by the present invention is as follows:
Mulberries: base: for the fruit ear of moraceae plants mulberry.Chemical analysis: sugary, acid of mixing, malic acid and vitamin B1, B2, C and carrotene.The aliphatic acid of Fructus Mori oil is mainly made up of linoleic acid and the stearic acid of amount, oleic acid etc..Nature and flavor: sweet, cold.Gui Jing: enter liver, kidney channel.Function cures mainly: tonifying liver, and kidney-nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.Controlling liver-kidney Yin deficiency, quench one's thirst, constipation, mesh is dark, tinnitus, scrofula, articular instability.
Grape pip: grape pip is that grape separates products therefrom after Grape Skin, grape pedicel after drying.Effect: 1, oxidation and removing free radicals, stops the destruction of radical pair human body cell.Protection Human autopsy tissues, prevents and treats heart disease, cancer, early ageing, diabetes, artery sclerosis etc. more than 100 kind by the disease caused by free radical.2, grape seed extract is rich in more than 100 kinds of active principles, wherein unrighted acid linoleic acid (a kind of needed by human but can not synthesize) accounts for 68-76% and occupies first of oil crops, it to be consumed the cholesterol of 20% by unsaturation to saturation state, it is possible to effectively reduces blood fat.3, the main extract-OPC (OPC) of grape pip has effect of whitening spot-removing: because OPC has superpower oxidation resistance, it it is 50 times of vitamin e, it it is 20 times of Vitamin C, energy delaying aging, prevention of arterial hardens, also there is the title of skin vitamin, there is fat-soluble and water miscible speciality, there is superpower whitening spot-removing effect.4, Proflavanol element can pass through blood-brain barrier (Blood-brain barrier) easily, it is a kind of particularly effective polyphenoils, and it can be highly concentrated in brain and nerve fiber, this characteristic makes it the polyphenoils that brain is ideal.
The fruit of Chinese wolfberry: base: for matrimony vine of solanaceae plant or the ripening fruits of lycium barbarum.Chemical analysis: 3.39 milligrams of % Han carrotene, 0.23 milligram of % of thiamine, 0.33 milligram of % of riboflavin, 1.7 milligrams of % of nicotinic acid, 3 milligrams of % of ascorbic acid in the fruit of Chinese wolfberry.Still isolate cupreol, linoleic acid.Pharmacological action: the most lipotropic effect;2. choline-like effect is intended;Nature and flavor: sweet are flat.Gui Jing: enter liver, kidney channel.Function cures mainly: nourshing kidney, moistening lung, tonifying liver, improving eyesight.Control liver-kidney Yin deficiency, soreness and weakness of waist and knees, dizzy, dizzy, the many tear of blurred vision, cough due to consumptive disease, quench one's thirst, seminal emission.
The fruit of Chinese magnoliavine: base: this product is the dry mature fruit of magnoliaceae schisandra.Chemical analysis: containing schizandrin, deoxidation schizandrin, new son simply element, schisandrol, schisantherin etc..Pharmacological action: normal person and the eyesight of persons suffering from ocular disorders can be improved and expand the visual field;Hearing is also had good impact, states the ability to see things in their true light that can improve skin receptor.Nature and flavor: sour, sweet, temperature.Gui Jing: return lung, the heart, kidney channel.Effect: restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.Curing mainly: for coughing for a long time, void is breathed heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, feeble pulse of losing heart, and interior heat is quenched one's thirst, palpitation and insomnia.
Barrenwort: base: for Berberidaceae plant barrenwort, Epimedium brevicornum or the cauline leaf of Epimedium sagittatum.Chemical analysis: barrenwort stem, leaf contain icariine, leaf is still containing volatile oil, ceryl alcohol, 1 alkane, phytosterol, tannin, grease.Aliphatic acid in fat oil has palmitic acid, stearic acid, oleic acid, linoleic acid.Pharmacological action: 1. affect sexual performance;2. microorganism there is inhibitory action;3. antibechic, eliminate the phlegm and antiasthmatic effect;4. other effects: extraction ofHerba Epimedii has a hypotensive effect to rabbit, makes the secretion of urine increase in a small amount, suppresses it the most on the contrary, isolated rabbit intestines are had inhibitory action, suppression after isolated uterine then first excitement, oral hyperglycemic rat blood sugar can be made to decline.Nature and flavor: Xin Gan, temperature.Gui Jing: enter liver, kidney channel.Function cures mainly: tonifying kidney and strengthening yang, dispels rheumatism.Controlling impotence not lift, dribbling urination, muscles and bones contraction is anxious, and hemiplegia, waist-leg weakness, arthralgia due to wind-dampness, four limbs are meciless.
Grape wine: grape wine is the high-grade drink with multiple nutritional components.Appropriateness drink grape wine can directly nervous system generation effect to human body, improve the Zhang Du of muscle.In addition, the several amino acids that contains in grape wine, minerals and vitamins etc., can directly be absorbed by the body.Therefore the physiological function of maintenance and regulation human body can be played good effect by grape wine.Especially more preferable to effect in poor health, to suffer from sleep-disorder person and the elderly.It may be said that grape wine is a good invigorant.It addition, the tannin in grape wine, it is also possible to adjust the shrinkage of smooth muscle fibers in intestinal muscle system, adjust the function of colon, colitis is had certain effect.Although the nutritive value of grape wine is the highest, but it is the one of wine after all, always has certain alcohol content.Therefore, no matter grape wine has great effect, all can not excess drink.Otherwise, it will destroy the immunity function of human body, the ill chance of human body is increased.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion (35g/ part): mulberries 36 parts;Grape pip 10 parts;The fruit of Chinese wolfberry 21 parts;18 parts of the fruit of Chinese magnoliavine;Barrenwort 19 parts;Pollen 5 parts;Grape juice 325 parts.
The anti-aging preparation of wine of above-mentioned one is:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 8 times amount, extract twice, the most each extraction 58 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 10 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take cabernet sauvignon grape juice to be placed in fermentation tank, add the yeast of 0.015 times of grape juice amount and step (1) process after mulberries, seal, shake up, in 18 DEG C of cold fermentations 6 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds Flos Rosae Rugosas pollen and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 10 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The drinking method of gained grape wine of the present invention is: once a day, and each 50-80mL can long-term taking.
Typical case: Liu XX, female, 50 years old, people from Heze.Patient occurs the senile symptoms such as insomnia forgetfulness, failure of memory symptom, the gradually decline of hearing and eyesight the year before without obvious inducement.Sometimes go up the thing also kept in mind for a second, will forget in a moment, and be difficult to bring ...back.A lot of worry is increased with household to oneself.The daughter of Mrs Liu talked about the situation of oneself mother with friend in talking later, and friends also have deep feeling.Surprisingly learnt that our anti-aging effect of grape wine is fine, had bought several bottles of effects of having a try to mother then later.Having taken after two months, Mrs Liu is found surprisingly that oneself mental restoration, and appetite strengthens, doing work energetic, therefore allow again daughter to oneself having bought a bit, the symptom such as present Mrs's Liu insomnia forgetfulness has disappeared, memory is improved, and Mrs Liu still takes, without other bad reactions adhering to.
Embodiment 2 A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion (15g/ part): mulberries 48 parts;Grape pip 16 parts;The fruit of Chinese wolfberry 34 parts;26 parts of the fruit of Chinese magnoliavine;Barrenwort 28 parts;Pollen 10 parts;Grape juice 528 parts.
The anti-aging preparation of wine of above-mentioned one is:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 12 times amount, extract twice, the most each extraction 76 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 16 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take cabernet sauvignon grape juice to be placed in fermentation tank, add the yeast of 0.015 times of grape juice amount and step (1) process after mulberries, seal, shake up, in 26 DEG C of cold fermentations 10 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds pollen powder of sweet osmanthus and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 20 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The drinking method of gained grape wine of the present invention is: once a day, and each 50-80mL can long-term taking.
Embodiment 3 A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion (30g/ part): mulberries 40 parts;Grape pip 12 parts;The fruit of Chinese wolfberry 25 parts;20 parts of the fruit of Chinese magnoliavine;Barrenwort 22 parts;Pollen 7 parts;Grape juice 365 parts.
The anti-aging preparation of wine of above-mentioned one is:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 9 times amount, extract twice, the most each extraction 64 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 12 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take grape juice to be placed in fermentation tank, add the yeast of 0.015 times of grape juice amount and step (1) process after mulberries, seal, shake up, in 20 DEG C of cold fermentations 7 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds Flos Rosae Rugosas pollen and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 13 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The drinking method of gained grape wine of the present invention is: once a day, and each 50-80mL can long-term taking.
Embodiment 4 A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion (20g/ part): mulberries 44 parts;Grape pip 14 parts;The fruit of Chinese wolfberry 30 parts;24 parts of the fruit of Chinese magnoliavine;Barrenwort 25 parts;Pollen 8 parts;Grape juice 488 parts.
The anti-aging preparation of wine of above-mentioned one is:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 11 times amount, extract twice, the most each extraction 70 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 14 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take grape juice to be placed in fermentation tank, add the yeast of 0.015 times of grape juice amount and step (1) process after mulberries, seal, shake up, in 24 DEG C of cold fermentations 9 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds chrysanthemum powder and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 17 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The drinking method of gained grape wine of the present invention is: once a day, and each 50-80mL can long-term taking.
Typical case: Zhao XX, female, 45 years old.Mrs Zhao is a single mom; one people works while the son that looks after to go to school; frequent busy complete work goes again to manage household affairs; every day is busy not to stop, and nearest Mrs Zhao profoundly experiences health not as in the past, often has a pain in the back; memory also declines; often forgetting east and forget west, skin is the oldest and the most feeble, many that people is aged.Deep annoyings Mrs Zhao.Take a kind of anti-aging grape wine of the present embodiment gained, once a day, each 50-80mL.After taking one month, the symptom that Mrs Zhao has a pain in the back substantially alleviates, and skin starts gloss occur, continuing to take one month, Mrs Zhao, transference cure of having a pain in the back, fatigue symptom disappears, to have a great spirit, facial wrinkles disappears, and skin smooth is ruddy, and presents full state, aging skin is improved comprehensively, whole people seem young good the most how old, present Mrs Zhao still takes, without any discomfort symptom adhering to every day.
Embodiment 5 A kind of anti-aging grape wine, is prepared from by following raw materials according, is weight portion (25g/ part): mulberries 42 parts;Grape pip 13 parts;The fruit of Chinese wolfberry 27.5 parts;22 parts of the fruit of Chinese magnoliavine;Barrenwort 23.5 parts;Pollen 7.5 parts;Grape juice 426.5 parts.
The anti-aging preparation of wine of above-mentioned one is:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 10 times amount, extract twice, the most each extraction 67 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 13 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take grape juice to be placed in fermentation tank, add the yeast of 0.015 times of grape juice amount and step (1) process after mulberries, seal, shake up, in 22 DEG C of cold fermentations 8 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds Flos Rosae Rugosas pollen and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 15 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The drinking method of gained grape wine of the present invention is: once a day, and each 50-80mL can long-term taking.
Test example 1 The clinical practice of a kind of anti-aging grape wine of gained of the present invention (embodiment 5): in December ,-2013 in March, 2010,5 hospitals' screenings because of the medical 312 example patients of tired senile symptom, the wherein male sex 123 example, women 189 example, the age 35-62 year.All patients are randomly divided into experimental group and control group.Two groups of patients, at the aspect such as sex, the state of an illness, through statistical procedures no significant difference (P > 0.05), have comparativity.Wherein, experimental group takes products obtained therefrom of the present invention, and instructions of taking is: once a day, each 50-80mL.Control group takes other products (such as fungi Wild glossy ganoderma tea, Tai Ji pellet, Hongjingtian instant tea etc.).Curative effect situation criterion: recovery from illness: fatigue symptom disappears, and senile symptom is improved comprehensively;Effective: fatigue symptom is substantially alleviated, senile symptom be improved significantly;Invalid: fatigue symptom is effectively alleviated, senile symptom is not improved.Total effective rate=cure rate+obvious effective rate.Observation takes two months altogether.Observed result is as shown in table 1.
Table 1: take two groups of patient treatment outcome after this product
Result for the treatment of: 142 examples of fully recovering (71%), effective 57 examples (28.5%), invalid 1 example (0.5%), total effective rate is 99.5%, and treatment group effect is substantially better than control group.
The present invention selects mulberries, grape pip, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, barrenwort, pollen and grape juice totally 7 to be prepared from for raw material.Wherein, barrenwort has promoting blood circulation, mends governor vessel, kidney-Yang invigorating, effect of controlling nocturnal emission with astringent drugs gas;Mulberries tonifying liver, kidney-nourishing, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow liquid;Main extract-the OPC of grape pip (OPC) has effect of whitening spot-removing;Liver-kidney Yin deficiency controlled by the fruit of Chinese wolfberry, soreness and weakness of waist and knees, dizzy, dizzy;Fruit of Chinese magnoliavine convergence is astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.All medicines share, and have peaceful heart intelligence development, brain-tonifying and kidney-nourishing, improve body immune function, constitutional effect.Taking two months, treatment group is efficient is 99.5%, and control group is only 83%.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that technical scheme is not limited to above-described embodiment, it is also possible to have many variations.Those of ordinary skill in the art, with the present invention undoubted the obtaining of clearly disclosed or according to file written description, be all considered as this patent scope of the claimed.

Claims (6)

1. an anti-aging preparation of wine, it is characterised in that take following raw materials according, is weight portion: mulberries 42;Grape pip 13;The fruit of Chinese wolfberry 27.5;The fruit of Chinese magnoliavine 22;Barrenwort 23.5;Pollen 7.5;Grape juice 426.5;Step is as follows:
(1) fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, grape pip and barrenwort are pulverized respectively, together it is placed in Chinese medicament extracting device, adds 90 DEG C of deionized waters of 9-11 times amount, extract twice, the most each extraction 67 minutes, filter, merge extract, be evaporated to the 1/3 of original volume, then it is centrifuged 13 minutes with the rotating speed of 5000r/min, take supernatant, continue to be concentrated into the 1/4 of liquid volume, obtain mixing water extract standby;Mulberries are rubbed, standby;
(2) take grape juice to be placed in fermentation tank, the mulberries after the yeast of 0.015 times of grape juice amount of addition and step (1) process, seal, shake up, in 20-24 DEG C of cold fermentation 7-9 days;
(3) the liquid filtered through gauze after step (2) fermentation, stays juice to remove slag, and filtrate loads in another aseptic fermentation tank, adds pollen and step (1) gained mixing water extract, mix, degerming, seal, continue fermentation 13-17 days, filter at low temperature, obtain preliminary grape wine;
(4) the preliminary grape wine of step (3) gained changes bottle contain, stand at low temperature, take supernatant, filter, degerming, dispense and get final product.
The anti-aging preparation of wine of one the most according to claim 1, it is characterised in that step (1) adds the deionized water of 10 times amount.
The anti-aging preparation of wine of one the most according to claim 1, it is characterised in that the temperature of step (2) cold fermentation is 22 DEG C.
The anti-aging preparation of wine of one the most according to claim 1, it is characterised in that step (2) cold fermentation 8 days.
The anti-aging preparation of wine of one the most according to claim 1, it is characterised in that in step (3), added pollen is the one in Flos Rosae Rugosas pollen, pollen powder of sweet osmanthus and chrysanthemum powder.
The anti-aging preparation of wine of one the most according to claim 1, it is characterised in that step (3) continues fermentation 15 days.
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