CN104687044A - Functional food for relieving male sexual dysfunction and resisting fatigue - Google Patents
Functional food for relieving male sexual dysfunction and resisting fatigue Download PDFInfo
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Abstract
The invention discloses a functional food for relieving male sexual dysfunction and resisting fatigue. The functional food contains maca powder. The functional food disclosed by the invention is capable of obviously improving the testosterone concentration in blood plasma of a human body and the conversion rate of hepatic glycogen (the glucose concentration in the blood is maintained at a stable level and is not easily lowered due to continuous movement), so as to effectively relieve MSD and improve the anti-fatigue property of the human body.
Description
Technical field
The present invention relates to a kind of functional food, be specifically related to a kind of functional food alleviating male sexual disfunction, antifatigue.
Background technology
Male sexual disfunction (MSD) refers to various disorder or the defect of male's sexual, comprise sexual desire and suppress (or Inhibited sexual desire, ISD), erectile dysfunction (ED) or impotence and premature ejaculation (PE, early send out also referred to as ejaculation fast, in advance ejaculation or ejaculation) and anorgasmy, how relevant with the secretion of the hormone such as testosterone, cortisol.Application PDE5 inhibitor, as silaenafil (sildenafil), Vardenafil (vardenafil) and Tadalafei (tadalafil), can successful treatment ED.At present the successful treatment of PE is comprised to the anesthesia frost (as lidocaine, prilocaine and combination thereof) and SSRI antidepressant that reduce penile sense, as Paxil, Prozac and Sertraline, but its effect is unsatisfactory and excessive use has obvious bad reaction.In addition, testosterone also has and promotes skeletal muscle and bone growth, stimulation RBC acceptor garland rate, increases the effect of Body development deposit, has close relationship with the locomitivity of human body, the growth of muscle strength, tired elimination etc.Research shows that long-time hard training or over training all can cause testosterone concentration in blood to decline, and this phenomenon is called as " motility hypoadenia " or " the low testosterone of sports type ".
Summary of the invention
In view of this, the present invention discloses a kind of functional food significantly improving human body anti-fatigue ability, effectively alleviate male sexual disfunction simultaneously.
Object of the present invention is achieved through the following technical solutions: a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Also comprise 100 ~ 230 portions of red dates, 20 ~ 30 parts of sealworts, 200 ~ 300 parts of malt syrups by weight.
Described pueraria root powder can select any one commercially available existing techniques in realizing.For Cruciferae (Cruciferae) Lepidium (Lepidium) plant, formal name used at school Lepidium meyenii.It is generally acknowledged that agate coffee has antifatigue, improve sperm quality, regain one's strength of body, improving water flood, anti-climacteric, active fertility, strengthens the effects such as memory.But the active ingredient in agate coffee plant is by the impact of the conditions such as extracting method, and quality is comparatively unstable.Simultaneously zoopery and clinically also to show, direct oral card agate powder is to alleviating MSD, the effect of antifatigue not obvious.And adopt the mode of injection very easily to cause allergic reaction.The pueraria root powder that agate coffee of the present invention selects the agate coffee in mountain area, Andean, South America to make, water content should control between 0-2% (free state water).
Described sodium carboxymethylcellulose, also known as: sanlose, carboxymethyl cellulose, CMC, Carboxymethyl, Cellulose Sodium, Sodium salt of Caboxy Methyl Cellulose, is a kind of food additives, is usually used in thickener, binding agent as food.Sodium carboxymethylcellulose of the present invention can select any one existing techniques in realizing.
The molecular formula of described D-sorbite is C
6h
14o
6.It is common sweetening agent.
Described ginseng extract refer to gather from fresh Araliaceae ginseng (Panax ginseng C.A.Mey), complete stool, the prior art such as lixiviate, two-phase extraction can be selected to obtain.Ginseng has certain anti-fatigue effect.Ginseng of the present invention is fresh ginseng complete stool (containing blade, stem, root).
Designer finds under study for action, the D-sorbite of a small amount of sodium carboxymethylcellulose and trace is added in agate coffee goods, and be equipped with appropriate ginseng, effectively can improve the susceptibility of human body to agate coffee goods, significantly improve the conversion rate (show as the concentration of glucose in blood maintain stable level and not easily because persistent movement declines) of testosterone concentration in human plasma and hepatic glycogen, thus effectively alleviate MSD and improve the anti-fatigue performance of human body.Any one of any removing sodium carboxymethylcellulose or D-sorbite, above-mentioned effect disappears all thereupon.
Utilize above-mentioned composition, the health products of any one form can be configured in conjunction with known technology, as Maca health wine, health drink, tablet etc.For improving, in and agate coffee and the property of medicine, reduce its stimulation to digestion, 100 ~ 230 portions of red dates, 20 ~ 30 parts of sealworts, 200 ~ 300 parts of malt syrups by weight can also be added in formula.Red date, sealwort etc. are commercially available drying product.
Also comprising 400 ~ 650 parts of ethanol mass fractions is by weight the rice wine of 30 ~ 50% and the deionized water of 300 ~ 400 parts.
As preferred embodiment, also comprise eclipta leaf extract 0.2 ~ 0.9 part;
It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 10 ~ 30 times is in the acetic acid solution of 5 ~ 8%, at the temperature of 35 ~ 45 DEG C, blowing air left standstill after 20 ~ 30 days, add infusion at 70 ~ 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 30 ~ 50 minutes, filter the filtrate obtained;
It is after the particle of 1 ~ 3mm that described eclipta leaf extract refers to that eclipta blade is pulverized, being immersed in quality is in the honey of 20 ~ 25 times of eclipta fresh weight, every day refrigerates 14 hours with 1 ~ 6 DEG C with 50 ~ 60 DEG C of heating after 10 hours successively again, processes and obtains described ecliptae herba leaf extract after 5 ~ 15 days;
Described pueraria root powder refer to agate coffee root at 70 ~ 80 DEG C, relative humidity is leave standstill after 20 ~ 50 days in the environment of 60%, dry after 5 hours through 90 ~ 95 DEG C, through pulverizing the particle diameter that the obtains material at 0.5 ~ 0.8mm.
Ecliptae herba, also claims Eclipta prostrata (Eclipta prostrata), is feverfew, it is generally acknowledged and can promote hair growth.The extract of ecliptae herba blade is added in agate coffee goods, particularly when there being sodium carboxymethylcellulose to exist, the concentration (high sensitive) of testosterone in blood plasma can be improved after taking in short time, and within the longer time, maintain the testosterone of this concentration.
Relative to the ginseng extract that common extraction or extraction obtain, the ginseng ethanol extract being immersed in hot fermentation more than 20 days in acetic acid shows and more significantly promotes muscle growth effect, after feeding, and the hindlimb muscle weightening finish 4-12% of mouse.
Ecliptae herba blade is placed in honey high-temperature process, contributes to the organic matter generation brown stain in ecliptae herba, obtain the effect improving testosterone concentration in the described short time.This effect of ecliptae herba leaf extract without this process is more weak.The effect of K cryogenic treatment is to promote that active ingredient is separated out from ecliptae herba.Described honey is any one prior art.The materials such as the fructose in honey, vitamin and Apidae animal secretions
Through the agate coffee root of high temperature, high humidity treatment, its effect improving testosterone concentration in blood plasma is better.
A kind of method preparing described functional food, comprise following operation: described pueraria root powder being added volume is in its deionized water of 20 ~ 30 times, described sodium carboxymethylcellulose is added after being heated to 80 ~ 85 DEG C, continue be heated to 90 DEG C and keep 3 ~ 7min, add described D-sorbite, ginseng extract, eclipta leaf extract after being cooled to 60 ~ 67 DEG C, after insulation 20 ~ 30min, obtain described functional food.
Detailed description of the invention
The present invention to be described in further detail below in conjunction with embodiment for the ease of it will be appreciated by those skilled in the art that:
Embodiment 1
The present embodiment provides a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Further, eclipta leaf extract 0.5 part is also comprised;
It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 20 times is in the acetic acid solution of 7%, at the temperature of 40 DEG C, blowing air left standstill after 20 days, add infusion at 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 40 minutes, filter the filtrate obtained;
It is after the particle of 1 ~ 3mm that described eclipta leaf extract refers to that eclipta blade is pulverized, being immersed in quality is in the honey of 20 times of eclipta fresh weight, every day refrigerates 14 hours with 1 DEG C with 60 DEG C of heating after 10 hours successively again, processes and obtains described ecliptae herba leaf extract after 10 days;
Described pueraria root powder refer to agate coffee root at 75 DEG C, relative humidity is leave standstill after 30 days in the environment of 60%, dry after 5 hours through 91 DEG C, through pulverizing the particle diameter that the obtains material at 0.5 ~ 0.8mm.
The present embodiment also provides a kind of method preparing above-mentioned functions food, comprise following operation: described pueraria root powder being added volume is in its deionized water of 30 times, described sodium carboxymethylcellulose is added after being heated to 80 DEG C, continue be heated to 90 DEG C and keep 7min, add described D-sorbite, ginseng extract, eclipta leaf extract after being cooled to 60 DEG C, after insulation 20min, obtain described functional food.
Embodiment 2
The present embodiment provides a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Further, eclipta leaf extract 0.9 part is also comprised;
It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 10 times is in the acetic acid solution of 8%, at the temperature of 35 DEG C, blowing air left standstill after 30 days, add infusion at 70 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 50 minutes, filter the filtrate obtained;
After described eclipta leaf extract refers to the particle that eclipta blade is pulverized as 1mm, being immersed in quality is in the honey of 25 times of eclipta fresh weight, every day refrigerates 14 hours with 1 ~ 6 DEG C with 50 ~ 60 DEG C of heating after 10 hours successively again, processes and obtains described ecliptae herba leaf extract after 5 days;
Described pueraria root powder refer to agate coffee root at 80 DEG C, relative humidity is leave standstill after 20 days in the environment of 60%, dry after 5 hours through 95 DEG C, through pulverizing the particle diameter that the obtains material at 0.5mm.
Embodiment 3
The present embodiment provides a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Further, eclipta leaf extract 0.2 part is also comprised;
After described ginseng extract refers to the particle that ginseng complete stool is pulverized as 1.5mm, to add weight be the mass fraction of particle fresh weight 10 times is in the acetic acid solution of 8%, at the temperature of 35 DEG C, blowing air left standstill after 30 days, add infusion at 70 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 50 minutes, filter the filtrate obtained;
It is after the particle of 1 ~ 3mm that described eclipta leaf extract refers to that eclipta blade is pulverized, being immersed in quality is in the honey of 20 times of eclipta fresh weight, every day refrigerates 14 hours with 1 DEG C with 50 DEG C of heating after 10 hours successively again, processes and obtains described ecliptae herba leaf extract after 15 days;
Described pueraria root powder refer to agate coffee root at 70 DEG C, relative humidity is leave standstill after 50 days in the environment of 60%, dry after 5 hours through 90 DEG C, through pulverizing the particle diameter that the obtains material at 0.8mm.
Embodiment 4
The present embodiment provides a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Further, eclipta leaf extract 0.5 part is also comprised;
It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, and the ethanol infusion at 80 DEG C being ginseng fresh weight 20 times in weight, after 40 minutes, filters the filtrate obtained;
It is after the particle of 1 ~ 3mm that described eclipta leaf extract refers to that eclipta blade is pulverized, and being immersed in quality is within 130 minutes, obtain described ecliptae herba leaf extract with 60 DEG C of infusions in 20 times of deionized waters of eclipta fresh weight;
Described pueraria root powder is commercially available prod.
Embodiment 5
The present embodiment provides a kind of functional food alleviating male sexual disfunction, antifatigue, and its raw material comprises by weight:
Described pueraria root powder, sodium carboxymethylcellulose, D-sorbite are commercially available prod.It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 20 times is in the acetic acid solution of 7%, at the temperature of 40 DEG C, blowing air left standstill after 20 days, add infusion at 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 40 minutes, filter the filtrate obtained.
Comparative example 1
Our team's ratio provides a kind of functional food of antifatigue, and its raw material comprises by weight:
Pueraria root powder 80 parts;
Sodium carboxymethylcellulose 10 parts;
Ginseng extract 0.35 part.
Described pueraria root powder, sodium carboxymethylcellulose, D-sorbite are commercially available prod.It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 20 times is in the acetic acid solution of 7%, at the temperature of 40 DEG C, blowing air left standstill after 20 days, add infusion at 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 40 minutes, filter the filtrate obtained.
Comparative example 2
This comparative example provides the functional food of antifatigue, and its raw material comprises by weight:
Pueraria root powder 80 parts;
D-sorbite 0.005 part;
Ginseng extract 0.35 part.
Described pueraria root powder, sodium carboxymethylcellulose, D-sorbite are commercially available prod.It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 20 times is in the acetic acid solution of 7%, at the temperature of 40 DEG C, blowing air left standstill after 20 days, add infusion at 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 40 minutes, filter the filtrate obtained.
Mice plasma testosterone concentration is tested.
Adult male mice (body weight 113.11 ± 5.72g) is divided into 7 groups, often organizes 50, often group gavage feeding embodiment 1, embodiment 2, embodiment 4, embodiment 5, comparative example 1, comparative example 2 and physiological saline respectively, feeding dosage is 0.5g.Mice plasma testosterone concentration (radioimmunology) in test feeding reagent 48 hours, " barrenwort concoct before and after impact on mice plasma testosterone and accessory sex organ " (CHINA JOURNAL OF CHINESE MATERIA MEDICA that concrete steps can be delivered with reference to Niu Rui, 14th volume the 9th phase, in September, 1989).Its result is as shown in table 1.
Mouse muscle growth test.
With above-mentioned dosage gavage medicament once a day, supply commercially available mouse feed simultaneously, take food arbitrarily for mouse.After ten days, add up each group of mice weights, front to weight and experiment weight is subtracted each other, obtains the average weight growth rate of each group of mouse.Result is as table 2.
| Experimental group | Weight growth rate (%) |
| Embodiment 1 | 50.31 |
| Embodiment 2 | 52.20 |
| Embodiment 4 | 42.11 |
| Embodiment 5 | 36.23 |
| Comparative example 1 | 10.22 |
| Comparative example 2 | 9.91 |
| Physiological saline | 10.38 |
Mouse blood sugar concentration determination.
Often group chooses 10 mouse, orders about its swimming, test mouse blood sugar concentration after 60min in being gone in off the deep end.Its result is as shown in table 3.
Be more than wherein specific implementation of the present invention, it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these apparent replacement forms all belong to protection scope of the present invention.
Claims (6)
1. alleviate a functional food for male sexual disfunction, antifatigue, its raw material comprises by weight:
2. functional food according to claim 1, is characterized in that: also comprise 100 ~ 230 portions of red dates, 20 ~ 30 parts of sealworts, 200 ~ 300 parts of malt syrups by weight.
3. functional food according to claim 2, is characterized in that: also comprising 400 ~ 650 parts of ethanol mass fractions is by weight the rice wine of 30 ~ 50% and the deionized water of 300 ~ 400 parts.
4. the functional food according to any one of claims 1 to 3, is characterized in that:
It is after the particle of 0.9 ~ 1.5mm that described ginseng extract refers to that ginseng complete stool is pulverized, to add weight be the mass fraction of particle fresh weight 10 ~ 30 times is in the acetic acid solution of 5 ~ 8%, at the temperature of 35 ~ 45 DEG C, pass into air leave standstill after 20 ~ 30 days, add infusion at 70 ~ 80 DEG C such as the ethanol heavy with acetic acid solution etc. and, after 30 ~ 50 minutes, filter the filtrate obtained.
5. the functional food according to any one of claims 1 to 3, is characterized in that: also comprise eclipta leaf extract 0.2 ~ 0.9 part; It is after the particle of 1 ~ 3mm that described eclipta leaf extract refers to that eclipta blade is pulverized, being immersed in quality is in the honey of 20 ~ 25 times of eclipta fresh weight, every day refrigerates 14 hours with 1 ~ 6 DEG C with 50 ~ 60 DEG C of heating after 10 hours successively again, processes and obtains described ecliptae herba leaf extract after 5 ~ 15 days;
Described pueraria root powder refer to agate coffee root at 70 ~ 80 DEG C, relative humidity is leave standstill after 20 ~ 50 days in the environment of 60%, dry after 5 hours through 90 ~ 95 DEG C, through pulverizing the particle diameter that the obtains material at 0.5 ~ 0.8mm.
6. prepare the method for functional food described in claim 1 for one kind, comprise following operation: described pueraria root powder being added volume is in its deionized water of 20 ~ 30 times, described sodium carboxymethylcellulose is added after being heated to 80 ~ 85 DEG C, continue be heated to 90 DEG C and keep 3 ~ 7min, add described D-sorbite, ginseng extract, eclipta leaf extract after being cooled to 60 ~ 67 DEG C, after insulation 20 ~ 30min, obtain described functional food.
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| CN105055492A (en) * | 2015-08-12 | 2015-11-18 | 江苏艾兰得营养品有限公司 | Preparation for tonifying Yang, strengthening body and improving immunity and preparation method of preparation |
| CN105296300A (en) * | 2015-11-11 | 2016-02-03 | 王宝珍 | Maca and ginseng liquor and production process thereof |
| CN105341606A (en) * | 2015-12-04 | 2016-02-24 | 广东红珊瑚药业有限公司 | Fatigue preventing and immunity strengthening maca health-care drink and preparation method thereof |
| CN105614874A (en) * | 2016-03-11 | 2016-06-01 | 聊城大学 | Composition for relieving fatigue state |
| CN107050089A (en) * | 2017-03-29 | 2017-08-18 | 新疆旺源生物科技集团有限公司 | It is a kind of to significantly increase maca composition of immunity function and preparation method thereof |
| CN110313530A (en) * | 2019-07-04 | 2019-10-11 | 广东福东海药业有限公司 | A kind of precious tea of ginseng five and preparation method thereof improving function of male |
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| CN105055492A (en) * | 2015-08-12 | 2015-11-18 | 江苏艾兰得营养品有限公司 | Preparation for tonifying Yang, strengthening body and improving immunity and preparation method of preparation |
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| CN110313530A (en) * | 2019-07-04 | 2019-10-11 | 广东福东海药业有限公司 | A kind of precious tea of ginseng five and preparation method thereof improving function of male |
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