CN104187952A - Ginseng-sealwort composite sports health beverage - Google Patents
Ginseng-sealwort composite sports health beverage Download PDFInfo
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- CN104187952A CN104187952A CN201410397990.7A CN201410397990A CN104187952A CN 104187952 A CN104187952 A CN 104187952A CN 201410397990 A CN201410397990 A CN 201410397990A CN 104187952 A CN104187952 A CN 104187952A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a ginseng-sealwort composite sports health beverage and discloses a sports health beverage capable of resisting fatigue and enhancing immunity. The ginseng-sealwort composite sports health beverage is prepared from medical and edible raw materials including ginseng, sealwort, jujube and sea-buckthorn and has main functions of resisting fatigue and resisting oxidization according to the theory of traditional Chinese medicine of invigorating qi and blood, nourishing yin, promoting the secretion of saliva or body fluid, activating blood circulation to dissipate blood stasis and regulating yin and yang. Pharmacological tests are carried out to determine the optimal ratio of the four medical materials, extra active ingredients do not need to be added, and the requirements of sports beverages can be met; the ginseng-sealwort composite sports health beverage has the functions of invigorating qi and blood, nourishing yin, promoting the secretion of saliva or body fluid, activating blood circulation to dissipate blood stasis and relieving fatigue, and is suitable for relieving sports fatigue and other various activity fatigue. The ginseng-sealwort composite sports health beverage is especially suitable for relieving sports fatigue after doing sports.
Description
Technical field
The invention provides a kind of ginseng sealwort compound motion health drink, is a kind of Sports tonic drink of antifatigue and increasing immune power, and the health food of specifically preparing as raw material taking the article of dietotherapeutic, belongs to traditional Chinese medicine pharmaceutical technology field.
Background technology
Fatigue, is caused by body movement itself, and organism physiology process can not continue holds its function at specified level and (or) can not maintain predetermined exercise intensity " body movement ability decline phenomenon.Exercise induced fatigue is because motility stimulates the temporary transient phenomenon declining of the even whole body ability to work of caused tissue, organ.Exercise induced fatigue causes metabolic imbalance and the medical problem of body, tool following points feature: the fatigue of central nervous system, immunologic function decline, neuroendocrine function suppresses, hemopoietic system function suppresses, degradation under body anti-peroxidation ability.In recent years, the research level of sports medical science bound pair sports fatigue has been deep into molecular level, and periphery machine-processed passive movement medical circle tired and central nerve fatigue is thought two main movement fatigue mechanism, has become the focus of sports medical science research at present.
According to the Overall View of the traditional Chinese medical science, fatigue is considered to be exhausted by vim and vigour, marrow void, deficient QI of the spleen and stomach or deficiency of kidney-QI, or asthenic yin, the sun reason such as have a surplus causes deficiency of Yin Sheng Neire; The functions such as fatigue and body, vital essence and lung, spleen, kidney are closely related.Sports, the excess load of the particularly training of the large intensity in athletic sports or near limit intensity, fierceness, very large on the impact of muscles and bones meat and function, the consume of vital essence and energy is larger, more easily causes fatigue.The traditional Chinese medical science thinks that motion consumes impairment of the spleen kidney vigour; Motion causes cardiopulmonary vim and vigour deficiency, liver is lost to dredge and rushes down.Spirit mood high-pressure causes body in a kind of temporary transient non-equilibrium state, needs the adjusting of liver.Tired allomeric function state changes, and depends on the common adjusting of the five internal organs, and in physical fatigue state, liver occupy core status; Under spirituality fatigue state, attach most importance to the heart; Under the consumptive disease state of chronic fatigue syndrome, taking spleen kidney as crucial, also depend on the coordination of conscience and lung.
Sports drink on existing market, is all manually formulated, non-natural product.
Summary of the invention
The invention provides a kind of ginseng sealwort compound motion health drink, be a kind of natural motion health drink of alleviating tired solution, adopt the article composition of four traditional Chinese medicine food dual-purpose, not only tired crowd is had to antifatigue and oxidation resistant effect, fatigue-relieving rapidly, and can improve immunity of organisms.
Another object of the present invention is to provide the preparation method of these health products, through extraction, and the reasonable processes such as purification, the natural motion health drink of making, stable in properties, taking convenience, effect is obvious, without any side effects.
A kind of ginseng sealwort compound motion health drink of the present invention, by following raw materials by weight portion than making:
Ginseng 3～9, sealwort 20～40, date 30～70, sea-buckthorn 20～50.
A kind of ginseng sealwort compound motion health drink of the present invention, its optimum ratio is as follows:
Ginseng 5, sealwort 30, date 60, sea-buckthorn 30.
the preparation technology of a kind of ginseng sealwort compound motion health drink of the present invention, comprises the following steps:
Take in proportion said medicine, ginseng adopts 4～7 times of amount 40 ~ 60% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, and filling 200ml/ bottle, to obtain final product.
[usage and dosage] is oral, and according to amount of exercise, a suggestion day dose is: 200 to 600 ml/ time.
[efficacy effect] blood-enrich, Yin-nourishing and body fluid promoting, promoting blood circulation to remove blood stasis, fatigue-relieving.
side of the present invention separates and property of medicine analysis
The present invention is by ginseng, and sealwort, date, sea-buckthorn four tastes are that food is again the thing composition of medicine, according to traditional Chinese medical science Overall View, with blood-enrich, Yin-nourishing and body fluid promoting, promoting blood circulation to remove blood stasis, adjust the theory of negative and positive, with antifatigue, antioxygen turns to major function and the health food research carried out.Determine the best proportioning of four flavour of a drug through pharmacology test, not adding in addition any functional component, can meet the requirement of sports drink.Wherein, ginseng is sweet, tepor, and beneficial gas tonifying lung, to promote the production of body fluid, is the monarch drug in a prescription in side; Date is sweet, and temperature replenishes qi to invigorate the spleen, and replenishing blood for nourishing heart is ministerial drug.The monarch and his subjects share, and it plays blood-enrich, effect of Yin-nourishing and body fluid promoting.Sealwort, sea-buckthorn is adjuvant.Sealwort is sweet, flat, can bowl spares gas and the beneficial heart is adjusted the five internal organs and tonifying kidney-yin, and enrich blood tonifying yin and support taste, in Compendium of Material Medica, highlight its " mend all void, replenishing essence marrow, flat filling blood and moisten "; Sea-buckthorn acid, puckery, temperature, reinforcing spleen to promote digestion, promoting blood circulation to remove blood stasis, two medicines help monarch, ministerial drug to play blood-enrich hand in hand, Yin-nourishing and body fluid promoting, promoting blood circulation to remove blood stasis, effect of adjustment negative and positive, relieving sports fatigue after being applicable to move.
Four kinds of mutual synergy of each article that the present invention is used, reach dose little, the result for the treatment of that conciliation effect is best.The 3rd, join smart Sports tonic drink and adopt the modern art of carrying to join smart Sports tonic drink and prove that through functional trial and human clinical trial sports fatigue and various activities fatigue are had to positive mitigation.This product is natural motion beverage, and effectively fatigue-relieving, improves human body immunity, meanwhile, without any side effects.
Prove by animal experiment: ginseng, sealwort, date, sea-buckthorn four taste compatibilities, aspect pharmacological action: significant prolongation mice burden swimming time and swimming time; Can reduce the consumption of muscle glycogen, reduce glycolysis, and by strengthening lactic dehydrogenase (LDH) activity, promote that body obtains ATP by glycolytic pathway, accelerate lactic acid and change into pyruvic acid, reduce the accumulation of lactic acid; Can increase the content of hemoglobin in mouse red blood cell, can significantly increase mouse and breathe the availability to oxygen at every turn; Carry out power and exhaust exercise test, the content of superoxide dismutase (SOD) in may organizing by increase, thus make SOD increased activity, and then strengthen the scavenging action to free radical.The free radical producing while thering is antagonism strenuous exercise, the effect that slows down Exercise-induced Skeletal Muscle Fatigue; Can effectively reduce the content of hypothalamus 5-HT and GABA (GABA), improve the content of dopamine and acetylcholine.Illustrate that this preparation can have the situation of improving central neurotransmitter disorder after sports fatigue in various degree by different target spots, reaches the effect of resisting kinetic fatigue; Can be by increasing acetylcholine transferase activity, acetylcholine esterase inhibition activity, makes in brain that acetylcholine is synthetic, content increases, thereby alleviates central nervous system of rats fatigue state.
Aspect medicine: the compatible content that increases flavones in beverage of four article; Improve dissolubility and the clarity of beverage; Do not need additional any functional component, can make beverage reach the requirement of sports drink.
good effect of the present invention is:
According to the traditional Chinese medical science with blood-enrich, the theory of Yin-nourishing and body fluid promoting, promoting blood circulation to remove blood stasis, adjustment negative and positive, with antifatigue, antioxygen turns to major function, by the ginseng of medicine-food two-purpose, sealwort, date, sea-buckthorn raw material composition, determine the best proportioning of four flavour of a drug through pharmacology test, not adding in addition any functional component, can meet the requirement of sports drink; There is blood-enrich, Yin-nourishing and body fluid promoting, promoting blood circulation to remove blood stasis, effect of fatigue-relieving, is suitable for the fatigue of sports fatigue and other various activities.Relieving sports fatigue after being specially adapted to move.
Detailed description of the invention
embodiment 1
Take ginseng 3kg, sealwort 20kg, date 30kg, sea-buckthorn 20kg, ginseng adopts 4 times of amount 60% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, and filling 200ml/ bottle, to obtain final product.
embodiment 2
Take ginseng 5kg, sealwort 30kg, date 60kg, sea-buckthorn 30kg, ginseng adopts 5 times of amount 50% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, and filling 200ml/ bottle, to obtain final product.
embodiment 3
Take ginseng 9kg, sealwort 40kg, date 70kg, sea-buckthorn 50kg, ginseng adopts 4～7 times of amount 60% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, and filling 200ml/ bottle, to obtain final product.
embodiment 4
Take ginseng 5kg, sealwort 30kg, date 60kg, sea-buckthorn 40kg, ginseng adopts 7 times of amount 40% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, and filling 200ml/ bottle, to obtain final product.
show antifatigue effect of the present invention by following pharmacodynamic study:
Exercise induced fatigue refers to the phenomenon being declined by the body movement ability of body movement caused " organism physiology process can not continue; its function is on a specified level and (or) can not maintain predetermined exercise intensity " itself, is the problem that sporting world and sports medical science circle are paid close attention to.Existing research of widely applying Chinese medicine to eliminate exercise induced fatigue at present.This experiment is that the present invention of making taking ginseng, sealwort, date, sea-buckthorn as raw material is as given the test agent, according to traditional Chinese medical science organic conception, start with from " invigorate vital energy and yang ", application " yin-nourishing " method antagonistic movement fatigue, the sports drink for being developed as with anti-fatigue effect provides scientific basis.
1 materials and methods
1.1 material
1.1.1 animal used as test and grouping KM kind mouse SPF level, male, body weight 18～22g, purchased from Changchun institute of Biological Products Co., Ltd, production licence number: 2011-0003.Establish altogether 2 batches of experiments, the 1st batch of mouse is for the experiment of swimming with a load attached to the body time, and the 2nd batch of mouse is for blood lactic acid, urea nitrogen and hepatic glycogen determination experiment.The animal of every batch of experiment is all divided into 4 groups at random by body weight, every group 10, be respectively blank group, the embodiment of the present invention 1 ~ embodiment 4:5,10,15,20ml/kgd group, every day, (9 o'clock) gavage gave tested material on time, gavage volume 20ml/kg, blank group is to same volume distilled water.Gavage 14 days continuously.Animal freely ingests and drinks water.
1.1.2 tested material prescription of the present invention: ginseng, sealwort, date, sea-buckthorn.Get in proportion each medicine and mix, decoct, extract its main pharmacodynamics composition, it is the beverage of 0.125g/ ml that interpolation auxiliary material is made containing crude drug amount, and 4 DEG C of Refrigerator stores are for subsequent use.
1.1.3 instrument and reagent electronic balance; constant temperature swimming trunk (70 cm × 40, cm × 50 cm); blood lactic acid analyzer (Shandong); automatic clinical chemistry analyzer (CS series automatic clinical chemistry analyzer; Di Rui); ultraviolet-uisible spectrophotometer (T6 new century, Shanghai); Hepatic glycogen is measured kit (Nanjing is built up Bioengineering Research Institute and produced).
1.2 method
1.2.1 when weight is measured in experiment, within the 7th day and the 14th day, experiment finishes, measure respectively the weight of each group of mouse.
1.2.2 the 1st batch of last of swimming with a load attached to the body experiment gives after given the test agent 30 min, and mouse tail root bears a heavy burden, and loading weight is weight 5%.Mouse is put in the swimming trunk of depth of water 30cm, water temperature (25 ± 0.5) DEG C, record starts can not emerge time (s) of (death) as its swimming with a load attached to the body time to the whole submergeds of head from swimming.
1.2.3 blood lactic acid, serum urea nitrogen and the 2nd batch of last of hepatic glycogen mensuration give after given the test agent 30 min, and mouse socket of the eye venous blood sampling 20ul surveys the front lactic acid concn of swimming.Then after mouse being put in to water temperature and being 30 DEG C, swimming trunk went swimming 90 min of the depth of water 35 cm, stop, plucking immediately eyeball blood sampling.Get 20ul and measure the rear blood lactate level of swimming.Residue blood sample is placed 4 DEG C of refrigerator 3 h, centrifugal 15 min of 2 000 r/ min; After separation of serum, measure serum urea nitrogen with automatic clinical chemistry analyzer.Animal is put to death after getting blood immediately, gets liver and blots with filter paper after physiological saline rinsing, accurately takes liver 100 mg, by kit (anthrone method) mensuration hepatic glycogen level.
1. 3 statistical procedures data represent with x ± s, adopt SPSS18.0 software to carry out data statistic analysis.
2 results
1 the present invention on the impact of Mice Body quality from table 1, mouse no matter initial weight, mid-term body weight or whole opisthosoma quality, no significant difference between each group (P > 0.05).
Each group Mice Body mass change (x ± s, g, n=10) before and after first experiment of table 1
Each group Mice Body mass change (x ± s, g, n=10) before and after continued 1 second batch experiment
2 the present invention on the impact of mouse swimming time from table 2, the each dosage of the present invention all can obviously extend the mice burden swimming time, has conspicuousness poor (P < 0.01 or P < 0.05) with blank group.
3 the present invention on the impact of Mouse Blood lactic acid concn from table 2, after mouse movement, blood lactate concentration obviously increases before moving, the blood lactate concentration of the middle and high dosage group of the present invention, all significantly lower than blank group, has significant difference (P <0.01).
2. 4 the present invention are on the impact of mice serum urea nitrogen concentration from table 2, and after mouse movement, of the present invention group of blood serum urea nitrogen concentration reduces, and high dose group and blank group relatively have significant difference (P< 0.01).
5 the present invention on the impact of Mouse Liver glycogen content from table 2, the hepatic glycogen level of of the present invention group obviously increases, and middle and high dosage group and blank group relatively have significant difference (P < 0.01 or P < 0.05).And there is dose-effect relationship.
The impact (x ± s, n=10) of table 2 on mice burden swimming time, blood lactate level, blood serum urea nitrogen concentration and hepatic glycogen content
Note: with relatively * P<0.05 of blank group, * * P <0.01, * * * P <0.001.
3 discuss
Tired topmost performance is the decline of exercise tolerance, and exercise tolerance is the most direct index of reflection organism fatigue, and the length of swimming time can reflect the degree of animal movement fatigue; And lactic acid is the product of sugared anerobic glycolysis in body, in body, the accumulation of lactic acid, is a major reason that causes exercise induced fatigue; Stocking for the blood sugar level important in inhibiting that maintains when motion of hepatic glycogen, and central nervous system and some body cells (as red blood cell) only can utilize blood sugar to make the energy, thereby measure the stocking of hepatic glycogen of animal body, as the index of an antifatigue of evaluating body.After motion, hepatic glycogen content is higher, proves that anti-fatigue effect is better.Blood urea nitrogen is the metabolite of protein, in the time that body prolonged exercise can not obtain enough energy by blood sugar, catabolism of fat, protein and amino acid catabolism are just strengthened, and therefore serum urea nitrogen is the index of evaluating body ability to bear in the time of physical load.This experimental result shows, of the present invention group of mouse swimming time extends, blood Lactate reduces, and illustrate that this beverage can improve body aerobic sport ability to a certain extent, thereby delay fatigue time of occurrence accelerated the speed that Fatique after Sports is eliminated.Of the present invention group of hepatic glycogen content is apparently higher than blank group, and serum urea nitrogen is starkly lower than blank group, has illustrated and has better maintained hepatic glycogen content, improves the adaptive capacity of animal to exercise load.The effect of pointing out this sports drink to have certain delaying the emergence of fatigue, provides certain experimental basis for developing from now on for antifatigue food.
Claims (3)
1. a ginseng sealwort compound motion health drink, it is characterized in that by following raw materials by weight portion than making:
Ginseng 3～9, sealwort 20～40, date 30～70, sea-buckthorn 20～50.
2. a kind of ginseng sealwort compound motion health drink according to claim 1, its optimum ratio is as follows:
Ginseng 5, sealwort 30, date 60, sea-buckthorn 30.
3. according to the preparation technology of a kind of ginseng sealwort compound motion health drink described in claim 1,2, comprise the following steps:
Take in proportion said medicine, ginseng adopts 4～7 times of amount 40 ~ 60% alcohol extracts, reclaims ethanol to thick paste, adds 3～5 times of water gagings and dissolves, and leaves standstill, and filters, and filtrate is for subsequent use; Sealwort, date, sea-buckthorn add 6～8 times of water gagings and decoct 1～2 hour, and water extraction liquid is concentrated, and sedimentation agent purifies, and filter, and filtrate is mixed with filtrate for subsequent use, adds quantitative auxiliary material, filling and get final product.
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| CN110742274A (en) * | 2019-11-18 | 2020-02-04 | 河南敬一医药科技有限公司 | Prescription and process for improving healthy energy of human body and resisting aging |
| CN111165701A (en) * | 2019-11-28 | 2020-05-19 | 重庆市药物种植研究所 | Anti-fatigue beverage |
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