CN105368669A - Raw materials for health care wine capable of resisting fatigue and improving immunity and health care wine preparation method - Google Patents
Raw materials for health care wine capable of resisting fatigue and improving immunity and health care wine preparation method Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
Abstract
The invention discloses a formula for health care wine capable of resisting fatigue and improving the immunity and a preparation method. According to the formula, ginseng, horseradish tree leaves, maca, gorgon euryale seeds, rhizoma polygonati, lycium barbarum, mulberries, raspberries and cortex cinnamomi are taken as raw materials according to a certain weight ratio, rock candy, honey, Chinese dates and food additives are added or not added, and then the compound wine is prepared through the technologies of extracting, separating, blending, clarifying, filtering, filling and the like. The health care wine is suitable for sub-health groups who are in a high-pressure high-intensity working environment, are prone to fatigue and need to improve the immunity or general staff, white-collar workers and middle and old aged groups who need to relieve the pressure.
Description
Technical field
The present invention relates to a kind of antifatigue and improve the composition of raw materials of immunizing power health promoting wine and the preparation method of health promoting wine thereof.
Background technology
Health promoting wine has the history of thousands of years, is the important component part of Chinese Medicine science.Multiple medicinal liquor is had to control the record of disease body-building in the successive dynasties medicine works of China, as: have 5 vina formulas in " 52 Bingfang " at least.Along with the raising of people's health care consciousness, consumption idea and health perception strengthen gradually, and popular alcohol drinking patterns is also in change.Health promoting wine is this not only to have been comprised white wine speciality but also had started to be subject to concern and the attention of the people with the drink of health-care effect.
Modern life rhythm is accelerated, and the pressure of people also increases severely day by day.Before pressure face, people often feel tired tired, especially working clan, and every day works from dawn to dusk, and sooner or later shuttles back and forth in city, repeats same work, battle-weary.According to WHO investigation, the whole world has the people of more than 35% to be in fatigue state, and middle-aged male crowd fatigue state reaches 60%.Tired appearance, can cause motor capacity reduction, working efficiency reduces, mistake and accident increases, fighting capacity goes down.Can not get timely recovery after occurring if tired, accumulate gradually, also can cause " overwork ", there is chronic fatigue syndrome, " overtraining syndrome " etc., make body generation endocrine regulation, immunity degradation, even occur organic disease, threaten human health.Therefore, develop the protective foods with antifatigue and strengthening immunity and just there is very real meaning.
Summary of the invention
The present invention aims to provide the formula of the feedstock composition of a kind of antifatigue and raising immunizing power health promoting wine, and another object of the present invention is to provide the preparation method of this health promoting wine.
The technical solution used in the present invention is, a feedstock composition for the health promoting wine of antifatigue and raising immunizing power, described composition is made up of following component by ratio of weight and the number of copies: ginseng 2 ~ 10 parts, leaf of Moringa 1 ~ 8 part, agate coffee 1 ~ 10 part, Gorgon fruit 2 ~ 20 parts, sealwort 3 ~ 15 parts, matrimony vine 3 ~ 20 parts, 3 ~ 20 parts, mulberry fruit, raspberry 2 ~ 20 parts, Chinese cassia tree 1 ~ 5 part.
Alternatively, in order to the improvement of mouthfeel, in described feedstock composition, add seasonings.Described seasonings is selected from rock sugar, honey, date or foodstuff additive etc.
Preferably, described feedstock composition is made up of following component by ratio of weight and the number of copies: ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts.
Health promoting wine preparation method of the present invention is, the preparation method of the health promoting wine of a kind of antifatigue and raising immunizing power, is characterized in that, comprise the steps:
1) preparation raw material composition is taken by following component and ratio of weight and number: ginseng 2 ~ 10 parts, leaf of Moringa 1 ~ 8 part, agate coffee 1 ~ 10 part, Gorgon fruit 2 ~ 20 parts, sealwort 3 ~ 15 parts, matrimony vine 3 ~ 20 parts, 3 ~ 20 parts, mulberry fruit, raspberry 2 ~ 20 parts, Chinese cassia tree 1 ~ 5 part; Add or do not add seasonings;
2) feedstock composition is soaked in white wine or edible ethanol.
Preferably, described feedstock composition is made up of following component by ratio of weight and the number of copies: ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts; Add or do not add seasonings.
Preferably, described preparation method comprises the steps:
1), selected after, take preparation raw material composition by described component and ratio of weight and number; The described general treating processes selected by Chinese medicine or food materials, mainly remove go mouldy, composition of damaging by worms.
2), by feedstock composition clean, dry, pulverize, sieving for standby;
3), the 2nd) add 40 ~ 70% (V/V) edible ethanol in feedstock composition after step process, preferably 65% edible ethanol, by ratio of weight and the number of copies, edible ethanol add-on is feedstock composition: edible ethanol=1:6 ~ 15, preferred 1:10;
4), lixiviate 14 ~ 36 days under room temperature, filter vat liquor, clear filtrate;
5), clear liquor adds distilled water to reduce ethanol content, leaves standstill, and essence filter, sterilizing, packaging gets product.
Pharmacological mechanism of the present invention is:
Ginseng is the root of Araliaceae ginseng PanaxginsengC.A.Mey., have reinforce vital energy, reinforce the spleen to benefit the lung, admittedly de-ly to promote the production of body fluid, the effect of intelligence development of calming the nerves.Modern pharmacology research shows.Ginseng energy enhancing body immunologic function; Sexual gland function can be strengthened, have the effect of gonad-stimulating hormone sample; To central nervous system, there is regulating effect, have booster action to the excitement of higher nerve system and process of inhibition, the handiness of nervous activity process can be strengthened, improve brainwork function; There is antifatigue, promote the synthesis of protein, RNA, DNA, promote hemopoietic system function, the effects such as cholesterol regulating metabolism.The excited Pituitary Adrenalcortical system of energy, improves stress reaction ability.In addition, anti-inflammatory, antianaphylaxis, antidiuresis and the multiple effect such as antitumor is still had.
Leaf of Moringa refers to originate in the leaf of the perennial tropical deciduous tree Moringa tree of India, has the effects such as hypoglycemic, lipopenicillinase, step-down, antitumor, anti-oxidant, defaecation, expelling parasite, improving water flood.Long-term edible can strengthen immune function of human body, delay senility, preventing disease.
Agate coffee is the rhizome of the Andean a kind of cress agate coffee LepidiummeyeniiWalp of original South America; containing the iron of higher amount; the compositions such as protein, amino acid, mineral substance zinc, taurine; can obviously to antifatigue; strengthen muscle endurance; resisted movement fatigue, helps firm immunity system, promotes body disease resistance.Its exclusive biologically active substance agate Ka alkene, agate Ka acid amides, can effective Reaction time shorten, has remarkable effect to balanced human's hormone secretion.
Gorgon fruit is the mature seed kernel of nymphaeaceae plant Gorgon euryale EuryaleferoxSalisb., the sweet puckery convergence of this product, and kind energy supplementing the kidney to control the nocturnal, controls not solid soreness of the waist and knees of suffering from a deficiency of the kidney, emission and spermatorrhea person.In addition, can invigorating the spleen dehumidify, restraining astringent or styptic treatment for spontaneous sweating, eliminating dampness and arresting leucorrhea, is the good merchantable brand demonstrate,proved under treatment belt.
Sealwort is the rhizome of liliaceous plant sealwort PolygonatumsibiricumRed., P. kingianum P.kingianumCoil.etHemsl. or David's-harp P.cyrtonemaHua.This product is sweet flat, and energy benefiting kidney-essence, delays senility, and improves the early ageing symptoms such as dizziness, soreness of the waist and knees, early whitening of beard and hair, has certain curative effect.In addition, this product can not only the moon of nourishing lung and kidney, and can invigoration spleen qi spleen cloudy, have and mend earth generating metal, mend the day after tomorrow to support congenital effect, the labor being applicable to YIN-deficiency of the lung and kidney is coughed chronic cough, the empty soft person of deficiency of spleen-QI and stomach-QI, fatigue and weakness, poor appetite, pulse condition.Modern pharmacological research finds: sealwort can improve body's immunity and promote the synthesis of DNA, RNA and protein, promotes lymphocyte transformation effect; There is significant anti-mycobacterium tuberculosis effect; Restraining effect is had to multiple pathogenic fungus; Also restraining effect is had to Corynebacterium diphtheriae, streptococcus aureus; Have and increase coronary flow and hypotensive effect, and can reducing blood-fat and alleviate Coronary Artery Atherosclerosis; The blood sugar caused suprarenin is too high in remarkable restraining effect; Suppress adrenocortical effect and anti-aging effects in addition.Matrimony vine is the mature fruit of plant of Solanaceae lycium barbarum LyciumbarbarumL..Can the moon of nourish liver and kidney, visual deterioration, the cataract or glaucoma blurred vision for the treatment of caused by asthenia of essence and blood, have a dizzy spell, soreness of the waist and knees, seminal emission lingering diarrhea, deafness, odontoseisis, early whitening of beard and hair, insomnia and dreamful sleep and the hepatic and renal YIN deficiency, hectic fever night sweat, the card such as to quench one's thirst.In addition, wolfberry fruit has promoter action to immunity, has immunoregulation effect simultaneously; Can plasma testosterone level be improved, play strong effect; Promoter action is had to hemopoietic function; Also remarkable effect in increasing leukocyte is had to normal healthy people; Anti-ageing, anti-mutation, antitumor, reducing blood-fat in addition, protect the liver and anti-fatty liveranti-fatty liver, hypoglycemic, hypotensive activity.
Mulberry fruit is the fruit ear of moraceae plants mulberry MomsalbaL., and the moon that can tonify the liver and kidney, promotes the production of body fluid to quench thirst, and relaxes bowel, and is applicable to the dizziness and tinnitus of the hepatic and renal YIN deficiency, the order secretly disease such as dim-sighted, articular instability, insomnia, early whitening of beard and hair.Modern pharmacological research finds: mulberry fruit has moderate to promote LT effect; Can promote that T cell is ripe, thus old and feeble T cell function is restored; Promoter action is had to young mouse humoral immune function; Promoter action is had to the growth of grain system granular cell; Prevent the leukopenic effect of caused by cyclophosphamide in addition.
Raspberry is the immature fruit of rosaceous plant rubus chingii Hu RubuschingiiHu.The contracting of inducing astrigency controlling nocturnal emission with astringent drugs can urinate, can tonify the liver and kidney again.Control emission due to deficiency of the kidney, involuntary emission, impotence, infertile and deficiency of the liver and kindey, order is not clear person secretly.
Chinese cassia tree is the dry bark of canella Chinese cassia tree CinnamomumcassiaPresl, can mend fire supporing yang, and Yiyang disappears the moon, action temperature and lasting, for controlling the key medicine of decline of the fire from the gate of life.Can be used for treating insufficiency of kidney-YANG, the impotence palace of decline of the fire from the gate of life is cold, waist knee crymodynia, night pollakiuria, the involuntary emission enuresis etc.Modern pharmacological research finds: Chinese cassia tree has vasodilation, stimulate circulation, strengthen coronary artery and cerebral blood flow (CBF), make vascular resistance under degradation effect; In vitro, its methanol extract and cinnamic aldehyde have anti-platelet aggregation, antithrombin effect; Oleum Cinnamomi, cinnamic aldehyde, Sodium.beta.-phenylacrylate have calmness, analgesia, the effect such as antipyretic, anticonvulsion; Oleum Cinnamomi can promote bowel movement, and digestive secretion is increased, and strengthens digestive function, gets rid of digestive tube pneumatosis, alleviates gastrointestinal spasm pain, and can cause metremia; Chinese cassia tree aqueous extract, ether extract are formed with restraining effect to experimentation on animals gastric ulcer.Styracin has the effect that human lung adenocarcinoma cell is reversed.
Beneficial effect of the present invention is, the five internal organs imbalance that the present invention is formed about fatigue according to the traditional Chinese medical science, vital essence blood consume viewpoint, and the tune benefit therapy principle deferring to the traditional Chinese medical science is filled a prescription, and each component, by mutually collaborative, produces antifatigue and the effect improving immunizing power; Product of the present invention belongs to the healthcare products of integration of drinking and medicinal herbs, can not produce any side effect, safe and reliable.This health promoting wine is applicable to be in high pressure, intensive work environment, easily tired, need the sub-health population improving immunizing power, or the common employee needing to release the pressure, white collar and person in middle and old age colony.
Technical scheme of the present invention is that contriver draws through groping summary in a large number for a long time, up to now, does not also find any report about health promoting wine of the present invention.
Below in conjunction with embodiment, the present invention will be further described
Embodiment
Embodiment 1:
Take ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts, remove go mouldy, composition of damaging by worms, with warm water rinse twice to clean, 60 DEG C of baking 5h, take out spreading for cooling, pulverization process, cross 40 mesh sieves for subsequent use.1:10 in mass ratio, pulverize medicine and add 65% (V/V) edible ethanol, lixiviate under room temperature, every 24h stirs 1 time, within 28 days, filters vat liquor; Filtrate adds 0.5% diatomite, stirs, with clear filtrate.Ethanol content is down to 38% (V/V) by clear liquor distilled water, adds rock sugar seasoning, and allotment terminates wine liquid in-15 DEG C of standing 24h.Leave standstill liquid and adopt the filter of 0.45um filter membrane essence, smart filtrate carries out physics and chemistry, sense organ, health detection, and qualifying liquid carries out canned through 0.0001% ozone sterilization, gets product.
Embodiment 2:
Take ginseng 2 parts, leaf of Moringa 8 parts, agate coffee 10 parts, Gorgon fruit 2 parts, sealwort 3 parts, matrimony vine 3 parts, 20 parts, mulberry fruit, raspberry 20 parts, Chinese cassia tree 5 parts, remove go mouldy, composition of damaging by worms, with warm water rinse twice to clean, 60 DEG C of baking 5h, take out spreading for cooling, pulverization process, cross 40 mesh sieves for subsequent use.1:10 in mass ratio, pulverize medicine and add 65% (V/V) edible ethanol, lixiviate under room temperature, every 24h stirs 1 time, within 28 days, filters vat liquor; Filtrate adds 0.5% diatomite, stirs, with clear filtrate.Ethanol content is down to 38% (V/V) by clear liquor distilled water, adds honey seasoning, and allotment terminates wine liquid in-15 DEG C of standing 24h.Leave standstill liquid and adopt the filter of 0.45um filter membrane essence, smart filtrate carries out physics and chemistry, sense organ, health detection, and qualifying liquid carries out canned through 0.0001% ozone sterilization, gets product.
Embodiment 3:
Take ginseng 10 parts, leaf of Moringa 2 parts, agate coffee 5 parts, Gorgon fruit 20 parts, sealwort 15 parts, matrimony vine 20 parts, 2 parts, mulberry fruit, raspberry 2 parts, Chinese cassia tree 1 part, remove go mouldy, composition of damaging by worms, with warm water rinse twice to clean, 60 DEG C of baking 5h, take out spreading for cooling, pulverization process, cross 40 mesh sieves for subsequent use.1:10 in mass ratio, pulverize medicine and add 65% (V/V) edible ethanol, lixiviate under room temperature, every 24h stirs 1 time, within 28 days, filters vat liquor; Filtrate adds 0.5% diatomite, stirs, with clear filtrate.Ethanol content is down to 38% (V/V) by clear liquor distilled water, adds date seasoning, and allotment terminates wine liquid in-15 DEG C of standing 24h.Leave standstill liquid and adopt the filter of 0.45um filter membrane essence, smart filtrate carries out physics and chemistry, sense organ, health detection, and qualifying liquid carries out canned through 0.0001% ozone sterilization, gets product.
Embodiment 4:
Take ginseng 5 parts, leaf of Moringa 5 parts, agate coffee 8 parts, Gorgon fruit 10 parts, sealwort 5 parts, matrimony vine 5 parts, 5 parts, mulberry fruit, raspberry 5 parts, Chinese cassia tree 3 parts, remove go mouldy, composition of damaging by worms, with warm water rinse twice to clean, 60 DEG C of baking 5h, take out spreading for cooling, pulverization process, cross 40 mesh sieves for subsequent use.1:10 in mass ratio, pulverize medicine and add 65% (V/V) edible ethanol, lixiviate under room temperature, every 24h stirs 1 time, within 28 days, filters vat liquor; Filtrate adds 0.5% diatomite, stirs, with clear filtrate.Ethanol content is down to 38% (V/V) by clear liquor distilled water, adds foodstuff additive seasoning, and allotment terminates wine liquid in-15 DEG C of standing 24h.Leave standstill liquid and adopt the filter of 0.45um filter membrane essence, smart filtrate carries out physics and chemistry, sense organ, health detection, and qualifying liquid carries out canned through 0.0001% ozone sterilization, gets product.
The product getting each embodiment carries out the result of pharmacological experiment
One, on the impact of mouse anti-reflecting fatigue effect
Adopt mice burden swimming and hypoxia endurance test, observe antifatigue effect of the present invention.
1. method: 30 mouse are carried out Loaned swimming test; experiment is grouped into Normal group, positive drug control group (10gkg-1 dosage; ZHENQI FUZHENG KELI suspension), health promoting wine group (50mlkg-1); each group of every day presses 10mLkg-1 administration 1 time; blank and model group gives equal-volume distilled water, continues 30d.Prepared by health promoting wine group medicine: get health promoting wine 50ml, after volatilizing, add water and be settled to containing crude drug 1gmL-1, with reference to human body consumption, converts out mouse consumption and gives gavage.30min after last administration, weigh in, mouse is placed in self-control swimming trunk [water temperature (25 ± 0.5) qC, depth of water 30cm] went swimming, mouse tail root bears a heavy burden the sandbag of 5% body weight, record mouse starts to the dead time (min), not have mouth breathing to be judged to death after mouse submerged from swimming.
Separately get 30 mouse and carry out hypoxia endurance test, grouping and administration as stated above, 2h after last administration, mouse is put into 500mL port grinding bottle, inside put the candle of a burning, use Vaseline closed bottle cap, timing immediately after candle anoxic is extinguished, record and extinguish to the mouse breathless time from candle.
2. result: ZHENQI FUZHENG KELI group, health promoting wine group can significant prolongation mice burden swimming time and mouse hypoxia endurance times.The results are shown in Table 1.
Table 1: on the impact of mice burden swimming, hypoxia endurance time
Two, on the impact of immune function of mice
1. method: mouse is divided into Normal group, positive drug control group (10gkg-1 dosage; ZHENQI FUZHENG KELI suspension), health promoting wine group (50mlkg-1); each group of every day presses 10mLkg-1 administration 1 time, and blank and model group gives equal-volume distilled water, continues 30d.Prepared by health promoting wine group medicine: get health promoting wine 50ml, after volatilizing, add water and be settled to containing crude drug 1gmL-1, with reference to human body consumption, converts out mouse consumption and gives gavage.26th day, with not containing the solvent treatment of DNF (DNFB) except blank group, all the other each group with DNFB sensitization, the method establishment delayed type hypersensitivity model that auricle excites, calculates and excites rear each group of mouse left and right auricle weightening finish value; After the 3rd week, except blank group, give immunosuppressor (hydrocortisone 40mgkg, intramuscular injection, 1 time every other day), totally 5 times, set up immunologic hypofunction mouse model.Mouse thymus, index and spleen index after calculating last administration lh, observe the impact on immune function of mice.
2. result: adopt 5%DNFB solution sensitization, 1%DNFB brings out, and makes delayed type hypersensitivity model, and after modeling, the remarkable swelling of mouse ear, ZHENQI FUZHENG KELI group, health promoting wine group can strengthen tardy super quick effect.The results are shown in Table 2.
Adopt immunosuppressor hydrocortisone to make immunosuppressed mice model, after modeling, mouse thymus index, spleen index decline, and ZHENQI FUZHENG KELI group, health promoting wine group group can significantly improve immunosuppressed mice spleen and thymus index.The results are shown in Table 3.
Table 2: on the impact of mouse delayed type hypersensitivity
Table 3: on the impact of immunosuppressed mice immune organ quality
From the above experimental results, health promoting wine of the present invention has enhancing mouse immune and antifatigue effect.
The above-mentioned implementation that the present invention describes is only in order to technical scheme of the present invention is clearly described, and can not be interpreted as and make any restriction to the present invention.The present invention has known multiple alternative or distortion in the art, under the prerequisite not departing from essential meaning of the present invention, all falls into protection scope of the present invention.
Claims (8)
1. a feedstock composition for the health promoting wine of antifatigue and raising immunizing power, described composition is made up of following component by ratio of weight and the number of copies: ginseng 2 ~ 10 parts, leaf of Moringa 1 ~ 8 part, agate coffee 1 ~ 10 part, Gorgon fruit 2 ~ 20 parts, sealwort 3 ~ 15 parts, matrimony vine 3 ~ 20 parts, 3 ~ 20 parts, mulberry fruit, raspberry 2 ~ 20 parts, Chinese cassia tree 1 ~ 5 part.
2. feedstock composition as claimed in claim 1, it is characterized in that, described feedstock composition is made up of following component by ratio of weight and the number of copies: ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts.
3. a feedstock composition for the health promoting wine of antifatigue and raising immunizing power, described composition is made up of following component by ratio of weight and the number of copies: ginseng 2 ~ 10 parts, leaf of Moringa 1 ~ 8 part, agate coffee 1 ~ 10 part, Gorgon fruit 2 ~ 20 parts, sealwort 3 ~ 15 parts, matrimony vine 3 ~ 20 parts, 3 ~ 20 parts, mulberry fruit, raspberry 2 ~ 20 parts, Chinese cassia tree 1 ~ 5 part; Seasonings is added in described feedstock composition.
4. feedstock composition as claimed in claim 3, it is characterized in that, described feedstock composition is made up of following component by ratio of weight and the number of copies: ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts; Seasonings is added in described feedstock composition.
5. a preparation method for the health promoting wine of antifatigue and raising immunizing power, is characterized in that, comprise the steps:
1) preparation raw material composition is taken by following component and ratio of weight and number: ginseng 2 ~ 10 parts, leaf of Moringa 1 ~ 8 part, agate coffee 1 ~ 10 part, Gorgon fruit 2 ~ 20 parts, sealwort 3 ~ 15 parts, matrimony vine 3 ~ 20 parts, 3 ~ 20 parts, mulberry fruit, raspberry 2 ~ 20 parts, Chinese cassia tree 1 ~ 5 part; Add or do not add seasonings;
2) feedstock composition is soaked in white wine or edible ethanol.
6. preparation method as claimed in claim 5, it is characterized in that, described feedstock composition is made up of following component by ratio of weight and the number of copies: ginseng 3 parts, leaf of Moringa 3 parts, agate coffee 3 parts, Gorgon fruit 8 parts, sealwort 8 parts, matrimony vine 10 parts, 10 parts, mulberry fruit, raspberry 3 parts, Chinese cassia tree 2.4 parts; Add or do not add seasonings.
7. the preparation method as described in claim 5 or 6, is characterized in that, described preparation method comprises the steps:
1), after selected, preparation raw material composition is taken by described component and ratio of weight and number;
2) feedstock composition is cleaned, dry, pulverize, sieving for standby;
3) the 2nd) add 40 ~ 70% edible ethanols in feedstock composition after step process, by ratio of weight and the number of copies, edible ethanol add-on is feedstock composition: edible ethanol=1:6 ~ 15;
4) lixiviate at least 28 days under room temperature, filters vat liquor, clear filtrate;
5) clear liquor adds distilled water to reduce ethanol content, leaves standstill, and essence filter, detect, sterilizing, packaging gets product.
8. preparation method as claimed in claim 7, is characterized in that, described preparation method 3) in step: adopt 65% edible ethanol, by ratio of weight and the number of copies, edible ethanol add-on is feedstock composition: edible ethanol=1:10.
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| CN105942129A (en) * | 2016-04-27 | 2016-09-21 | 佛山市聚成生化技术研发有限公司 | Effervescent tablet drink with fatigue relieving effects |
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| CN106987512A (en) * | 2017-06-08 | 2017-07-28 | 山东瑞芝生物科技有限公司 | A kind of health liquor and preparation method thereof |
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| CN107854610A (en) * | 2017-11-23 | 2018-03-30 | 新乡博凯生物技术有限公司 | A kind of plant composition of kidney-yang deficiency crowd health care and preparation method thereof |
| CN109762707A (en) * | 2019-03-01 | 2019-05-17 | 湖北艾中艾健康酒业有限公司 | A kind of health liquor and preparation method thereof |
| CN112450301A (en) * | 2020-10-15 | 2021-03-09 | 湖南省中医药研究院 | Health tea with anti-fatigue function and preparation method and drinking method thereof |
| CN112353917A (en) * | 2020-11-20 | 2021-02-12 | 通化承诚药业有限公司 | Deer penis cream and preparation method thereof |
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