CN104666114A - Wrinkle removing, anti-aging, skin activating and scar fading repair essence and preparation method thereof - Google Patents
Wrinkle removing, anti-aging, skin activating and scar fading repair essence and preparation method thereof Download PDFInfo
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- CN104666114A CN104666114A CN201510104270.1A CN201510104270A CN104666114A CN 104666114 A CN104666114 A CN 104666114A CN 201510104270 A CN201510104270 A CN 201510104270A CN 104666114 A CN104666114 A CN 104666114A
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- hyaluronic acid
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Abstract
The invention discloses wrinkle removing, anti-aging, skin activating and scar fading repair essence which comprises components in parts by weight as follows: 600-850 parts of sterile water, 60-200 parts of glycerin, 30-80 parts of sodium pyrrolidone carboxylic acid, 30-80 parts of 1,3-butanediol, 3-10 parts of collagen, 5-20 parts of panthenol, 3-10 parts of allantoin, 10-40 parts of hydroxyproline, 2-10 parts of bisabolol, 2-10 parts of hyaluronic acid, 0.5-2 parts of recombinant human epidermal growth factors and 1-5 parts of diazolidinyl urea. The preparation method comprises the following steps: (1), sterile water, glycerin, sodium pyrrolidone carboxylic acid, 1,3-butanediol and collagen are mixed uniformly with allantoin and are heated for 20 min at 85 DEG C; (2), the mixture is stirred for 20 min at the speed of 30 rpm and is cooled; (3), panthenol and hydroxyproline are added when the temperature is 55 DEG C, the mixture is uniformly mixed, residual components are added when the temperature is 40 DEG C, the mixture is uniformly mixed and then homogenized for 30s, and discharging is performed when the temperature is 30 DEG C, and the repair essence is obtained.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to that a kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence and preparation method thereof.
Background technology
With advancing age or the impact of extrinsic factor, moisture in skin starts to reduce gradually, fibroblastic synthesis capability also starts to decline gradually, collagen fiber generation crosslinking curing simultaneously, intercellular viscous polysaccharide is reduced, then skin just changes, no longer softness, high resilience and glossiness, and skin starts aging, old and feeble.Many metabolic enzymes activity of ageing skin start to decline, and hyaluronic acid wherein and Sulfates also start to reduce; Aging skin sebaceous gland and sweat gland atrophy, secretion reduces, horny layer hydration reduced capability, thus causes pachylosis, even dry and cracked.
Chinese invention patent application number be disclose in 201310500055.4 that a kind of reduce wrinkle is anti-ageing, Cucumber Extract, reparation whitening compositions, with weight, described compositions comprises following composition: hyaluronic acid 15%-30%, collagen protein 25%-40%, recombinant human epidermal growth factor 0.0001%-0.0009%, glycerol 5%-20%.Said composition effect is more single, and moistening effect is inadequate, and thus effect each other can not play moistening effect to skin to greatest extent, and it combines also can not reach to greatest extent and strengthens the natural repair ability of skin, effectively improves skin ageing phenomenon.
Summary of the invention
The present invention is directed to above-mentioned weak point and a kind of reduce wrinkle of providing is anti-ageing, Cucumber Extract, desalination cicatrix repair essence and preparation method thereof, the present invention is based on the effect of recombinant human epidermal growth factor and reach the natural repair ability of enhancing skin in conjunction with other moisturizing reparation raw material, effectively improve skin ageing phenomenon, thus reach that reduce wrinkle is anti-ageing, effect of Cucumber Extract, desalination cicatrix.
For achieving the above object, the technical solution adopted for the present invention to solve the technical problems is:
A kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 600-850 part, glycerol 60-200 part, pyrrolidone sodium carboxylate 30-80 part, 1,3 butylene glycol 30-80 part, collagen protein 3-10 part, pantothenylol 5-20 part, allantoin 3-10 part, hydroxyproline 10-40 part, bisabolol 2-10 part, hyaluronic acid 2-10 part, recombinant human epidermal growth factor 0.5-2 part, two hydroxy methylimidazole ureine 1-5 part.
Further, a kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 650-800 part, glycerol 80-160 part, pyrrolidone sodium carboxylate 35-75 part, 1,3 butylene glycol 35-75 part, collagen protein 3.5-8 part, pantothenylol 6-18 part, allantoin 3.5-8 part, hydroxyproline 15-35 part, bisabolol 2.5-8 part, hyaluronic acid 3-8 part, recombinant human epidermal growth factor 0.6-1.8 part, two hydroxy methylimidazole ureine 2-4 part.
Further, a kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 700-780 part, glycerol 90-140 part, pyrrolidone sodium carboxylate 40-55 part, 1,3 butylene glycol 40-55 part, collagen protein 4-6 part, pantothenylol 8-14 part, allantoin 4-6 part, hydroxyproline 20-30 part, bisabolol 3-6 part, hyaluronic acid 4-6 part, recombinant human epidermal growth factor 0.8-1.4 part, two hydroxy methylimidazole ureine 2.5-3.5 part.
Further, a kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 742 parts, glycerol 100 parts, pyrrolidone sodium carboxylate 50 parts, 1,3 butylene glycol 50 parts, collagen protein 5 parts, pantothenylol 10 parts, allantoin 5 parts, hydroxyproline 25 parts, bisabolol 4 parts, hyaluronic acid 5 parts, recombinant human epidermal growth factor 1 part, two hydroxy methylimidazole ureine 3 parts.
The preparation method that reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprises the following steps:
(1) load weighted sterilized water is added aqueous phase pot, and then add load weighted glycerol, pyrrolidone sodium carboxylate, 1-3 butanediol, collagen protein, allantoin successively, stirring and evenly mixing is also warming up to 85 DEG C, insulation 20min, for subsequent use;
(2) emulsifying kettle cleans up preheating 5 minutes final vacuums and is evacuated to 0.06-0.07MPa, is sucked in emulsifying kettle by aqueous phase material, and then start to stir, rotating speed is 30rpm, and mixing time is 20min, finally lowers the temperature;
(3) when temperature in emulsifying kettle is down to 55 DEG C, add load weighted pantothenylol, hydroxyproline stirs, when temperature is down to 40 DEG C, add bisabolol, hyaluronic acid solution, recombinant human epidermal growth factor, two hydroxy methylimidazole ureine stir, then homogenizing 30s, when temperature is down to 30 DEG C, discharging, obtains that reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repairs essence.
Further, described hyaluronic acid solution is that the sterilized water of hyaluronic acid 10 times of weight is heated to 50 DEG C, then adds in sterilized water by hyaluronic acid, is stirred to dissolving formation clear solution completely and obtains.
In the present invention's component used, glycerol, chemistry glycerol by name, be a kind of thick liquid of colourless, sweet in the mouth, glycerol, except having very strong water absorption, also can be used as solvent, the ductility of improving product, increases skin to the absorption of other compositions.
Pyrrolidone sodium carboxylate is naturally occurring a kind of material in skin, is amino acid whose derivant, has very strong hygroscopicity, even from air, absorb moisture.
1,3 butylene glycol has the feature such as odorless, good water solubility, can be used as wetting agent and softening agent.
Collagen protein is a kind of white, transparent powder, and the structure of its structure and human body skin collagen is closely similar, containing a large amount of aminoacid and hydrophilic group and a large amount of hydroxyls in molecule, therefore has good moisture retention and surface activity; Also have simultaneously and stop the tyrosine in skin to be converted into melanic effect, therefore collagen protein also has effect of whitening; Collagen protein adds in skin-care cosmetics, good with other material combination, and synergy is good, repair that can be effectively good to impaired skin.
Pantothenylol is vitamin B
5a kind of derivant, skin is not injured, after the product including pantothenylol is applied to skin, is absorbed by the skin, can vitamin B be transformed into
5, thus there is manufacture and upgrade bodily tissue, help wound healing, alleviate the effects such as allergic symptom.
Allantoin is a kind of nontoxic, tasteless, nonirritant, without hypersensitive white crystal, dissolves in hot water, has sterilization and anticorrosion, antioxidative effect, skin can be made to keep moisture, moisten after being applied to skin, soft, high resilience and gloss; In addition, allantoin can also promote tissue growth, accelerates the metabolic capabilities of cell, horny layer softening.
Hydroxyproline is the main constituent of collagen protein, and it as cosmetics additive, can have antioxidation, radiation-resistant effect.
Bisabolol is colourless to the yellow thick liquid of Caulis et Folium Oryzae, water-soluble, has stiff stability and strong skin-friendliness, also has antiinflammatory performance, for the protection of with nursing allergic skin.
Hyaluronic acid is a kind of acid mucopolysaccharide, with skin maturation and aging relevant, hyaluronic acid also has special water retention, it can improve the Nutrition and Metabolism of skin, make skin become tender smooth, increase elasticity, remove wrinkle, prevent aging, while moisturizing, also have the effect promoting alimentation.
Recombinant human epidermal growth factor is a kind of little peptide be made up of 53 amino acid residues, be a kind of somatomedin, have strong short splitting action to Various Tissues cell, the various cells of ectoderm and endodermal origin can be stimulated, accelerate the metabolism of cell, thus reach the effect of skin care; Recombinant human epidermal growth factor can also increase moisture content of skin, increases skin elasticity; Recombinant human epidermal growth factor can also promote skin corium emiocytosis rubber polymer fibril, the functional molecular such as polysaccharide and glycoprotein, makes that subcutaneous dermal tissue is full, muscle fiber arrangement is also closely neat, and then smooth away wrinkles, flap coverage etc.
Two hydroxy methylimidazole ureine is white mobility powder, has hygroscopicity, soluble in water, dissolves in propylene glycol and glycerol.
A kind of reduce wrinkle provided by the invention is anti-ageing, Cucumber Extract, desalination cicatrix repair essence and preparation method thereof, has following beneficial effect:
(1) reduce wrinkle provided by the invention anti-ageing, Cucumber Extract, desalination cicatrix is repaired essence raw material and is interacted, there is the effect of Synergistic, the reparation essence moistening effect prepared is good, skin can be repaired, smooth microgroove, all clean colour of skin, there is nitrogenize cicatrix, make effect of the bright brilliance of skin.
(2) the preparation method simple possible that a kind of reduce wrinkle provided by the invention is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, is easy to operation, can be mass.
Detailed description of the invention
Embodiment 1
A kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 742 parts, glycerol 100 parts, pyrrolidone sodium carboxylate 50 parts, 1,3 butylene glycol 50 parts, collagen protein 5 parts, pantothenylol 10 parts, allantoin 5 parts, hydroxyproline 25 parts, bisabolol 4 parts, hyaluronic acid 5 parts, recombinant human epidermal growth factor 1 part, two hydroxy methylimidazole ureine 3 parts.
The preparation method that this reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprises the following steps:
(1) load weighted sterilized water is added aqueous phase pot, and then adding load weighted glycerol, pyrrolidone sodium carboxylate, 1-3 butanediol, collagen protein, allantoin successively, stirring and evenly mixing is also warming up to 85 DEG C, and all materials all dissolve completely this moment, insulation 20min, for subsequent use;
(2) emulsifying kettle cleans up preheating 5 minutes final vacuums and is evacuated to 0.06-0.07MPa, is sucked in emulsifying kettle by aqueous phase material, and then start to stir, rotating speed is 30rpm, and mixing time is 20min, finally lowers the temperature;
(3) when temperature in emulsifying kettle is down to 55 DEG C, add load weighted pantothenylol, hydroxyproline stirs, when temperature is down to 40 DEG C, add bisabolol, hyaluronic acid solution, recombinant human epidermal growth factor, two hydroxy methylimidazole ureine stir, then homogenizing 30s, when temperature is down to 30 DEG C, discharging, obtains that reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repairs essence.
Wherein, the preparation method of hyaluronic acid solution is that the sterilized water of hyaluronic acid 10 times of weight is heated to 50 DEG C, then under agitation hyaluronic acid is slowly added aseptic enter in water, continue to be stirred to hyaluronic acid and dissolve completely, form clear solution.
Embodiment 2
A kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 826.5 parts, glycerol 70 parts, pyrrolidone sodium carboxylate 35 parts, 1,3 butylene glycol 35 parts, collagen protein 3 parts, pantothenylol 6 parts, allantoin 3 parts, hydroxyproline 15 parts, bisabolol 2 parts, hyaluronic acid 2 parts, recombinant human epidermal growth factor 0.5 part, two hydroxy methylimidazole ureine 2 parts.
The preparation method that this reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence is identical with embodiment 1.
Embodiment 3
A kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 773.7 parts, glycerol 90 parts, pyrrolidone sodium carboxylate 45 parts, 1,3 butylene glycol 45 parts, collagen protein 4 parts, pantothenylol 8 parts, allantoin 4 parts, hydroxyproline 20 parts, bisabolol 3 parts, hyaluronic acid 4 parts, recombinant human epidermal growth factor 0.8 part, two hydroxy methylimidazole ureine 2.5 parts.
The preparation method that this reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence is identical with embodiment 1.
Embodiment 4
A kind of reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, comprise following component and the parts by weight of each component are: sterilized water 703.8 parts, glycerol 120 parts, pyrrolidone sodium carboxylate 55 parts, 1,3 butylene glycol 55 parts, collagen protein 5.5 parts, pantothenylol 12 parts, allantoin 5.5 parts, hydroxyproline 28 parts, bisabolol 5 parts, hyaluronic acid 5.5 parts, recombinant human epidermal growth factor 1.2 parts, two hydroxy methylimidazole ureine 3.5 parts.
The preparation method that this reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repair essence is identical with embodiment 1.
A kind of reduce wrinkle provided by the invention is anti-ageing, Cucumber Extract, desalination cicatrix are repaired essence raw material and interacted, there is the effect of Synergistic, the reparation essence moistening effect that embodiment 1-4 prepares is good, skin can be repaired, smooth microgroove, all clean colour of skin, there is nitrogenize cicatrix, make effect of the bright brilliance of skin, wherein the reduce wrinkle prepared of embodiment 1 anti-ageing, Cucumber Extract, desalination cicatrix repairs essence best results.
Claims (6)
1. a reduce wrinkle anti-ageing, Cucumber Extract, desalination cicatrix repairs essence, it is characterized in that, comprise following component and the parts by weight of each component are: sterilized water 600-850 part, glycerol 60-200 part, pyrrolidone sodium carboxylate 30-80 part, 1,3 butylene glycol 30-80 part, collagen protein 3-10 part, pantothenylol 5-20 part, allantoin 3-10 part, hydroxyproline 10-40 part, bisabolol 2-10 part, hyaluronic acid 2-10 part, recombinant human epidermal growth factor 0.5-2 part, two hydroxy methylimidazole ureine 1-5 part.
2. a kind of reduce wrinkle according to claim 1 anti-ageing, Cucumber Extract, desalination cicatrix repairs essence, it is characterized in that, comprise following component and the parts by weight of each component are: sterilized water 650-800 part, glycerol 80-160 part, pyrrolidone sodium carboxylate 35-75 part, 1,3 butylene glycol 35-75 part, collagen protein 3.5-8 part, pantothenylol 6-18 part, allantoin 3.5-8 part, hydroxyproline 15-35 part, bisabolol 2.5-8 part, hyaluronic acid 3-8 part, recombinant human epidermal growth factor 0.6-1.8 part, two hydroxy methylimidazole ureine 2-4 part.
3. a kind of reduce wrinkle according to claim 1 anti-ageing, Cucumber Extract, desalination cicatrix repairs essence, it is characterized in that, comprise following component and the parts by weight of each component are: sterilized water 700-780 part, glycerol 90-140 part, pyrrolidone sodium carboxylate 40-55 part, 1,3 butylene glycol 40-55 part, collagen protein 4-6 part, pantothenylol 8-14 part, allantoin 4-6 part, hydroxyproline 20-30 part, bisabolol 3-6 part, hyaluronic acid 4-6 part, recombinant human epidermal growth factor 0.8-1.4 part, two hydroxy methylimidazole ureine 2.5-3.5 part.
4. a kind of reduce wrinkle according to claim 1 anti-ageing, Cucumber Extract, desalination cicatrix repairs essence, it is characterized in that, comprise following component and the parts by weight of each component are: sterilized water 742 parts, glycerol 100 parts, pyrrolidone sodium carboxylate 50 parts, 1,3 butylene glycol 50 parts, collagen protein 5 parts, pantothenylol 10 parts, allantoin 5 parts, hydroxyproline 25 parts, bisabolol 4 parts, hyaluronic acid 5 parts, recombinant human epidermal growth factor 1 part, two hydroxy methylimidazole ureine 3 parts.
5. the preparation method that the reduce wrinkle according to any one of claim 1-4 is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, is characterized in that, comprise the following steps:
(1) load weighted sterilized water is added aqueous phase pot, and then add load weighted glycerol, pyrrolidone sodium carboxylate, 1-3 butanediol, collagen protein, allantoin successively, stirring and evenly mixing is also warming up to 85 DEG C, insulation 20min, for subsequent use;
(2) emulsifying kettle cleans up preheating 5 minutes final vacuums and is evacuated to 0.06-0.07MPa, is sucked in emulsifying kettle by aqueous phase material, and then start to stir, rotating speed is 30rpm, and mixing time is 20min, finally lowers the temperature;
(3) when temperature in emulsifying kettle is down to 55 DEG C, add load weighted pantothenylol, hydroxyproline stirs, when temperature is down to 40 DEG C, add bisabolol, hyaluronic acid solution, recombinant human epidermal growth factor, two hydroxy methylimidazole ureine stir, then homogenizing 30s, when temperature is down to 30 DEG C, discharging, obtains that reduce wrinkle is anti-ageing, Cucumber Extract, desalination cicatrix repairs essence.
6. the preparation method that a kind of reduce wrinkle according to claim 5 is anti-ageing, Cucumber Extract, desalination cicatrix repair essence, it is characterized in that, hyaluronic acid solution is that the sterilized water of hyaluronic acid 10 times of weight is heated to 50 DEG C, then hyaluronic acid is added in sterilized water, be stirred to dissolving formation clear solution completely and obtain.
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| CN201510104270.1A CN104666114A (en) | 2015-03-10 | 2015-03-10 | Wrinkle removing, anti-aging, skin activating and scar fading repair essence and preparation method thereof |
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| CN105287242A (en) * | 2015-11-11 | 2016-02-03 | 浙江元研生物科技有限公司 | Skin care product containing human stem cell growth factor and preparation method thereof |
| CN105727264A (en) * | 2016-03-24 | 2016-07-06 | 松原市颖奇经贸有限责任公司 | Scar repair liquid and preparation method thereof |
| CN105919860A (en) * | 2016-05-04 | 2016-09-07 | 福建春伦茶业集团有限公司 | Jasmine flower soothing gel |
| CN105919838A (en) * | 2016-06-14 | 2016-09-07 | 成都舒乐科技发展有限公司 | Skin care cosmetic product and preparation method |
| CN105997776A (en) * | 2016-05-10 | 2016-10-12 | 四川美咖生物科技有限公司 | Mask liquid with repairing function and preparation method thereof |
| CN106138521A (en) * | 2016-06-28 | 2016-11-23 | 郑州雷曼药业有限公司 | A kind of cicatrix repairs gel and preparation method thereof |
| CN107028830A (en) * | 2017-04-25 | 2017-08-11 | 徐子雁 | It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia |
| CN107184425A (en) * | 2017-07-25 | 2017-09-22 | 广州铭心化妆品有限公司 | A kind of moisturizing essence and preparation method thereof |
| CN107648591A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair emulsion and preparation method thereof |
| CN107648589A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair gel and preparation method thereof |
| CN107648590A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair composition and its preparation and application |
| CN107837205A (en) * | 2017-11-28 | 2018-03-27 | 苏州汇涵医用科技发展有限公司 | The preparation method of skin repair facial mask |
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| CN103784343A (en) * | 2014-02-20 | 2014-05-14 | 澳宝化妆品（惠州）有限公司 | Water-moisturizing repairing foundation make-up emulsion |
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| CN103784343A (en) * | 2014-02-20 | 2014-05-14 | 澳宝化妆品（惠州）有限公司 | Water-moisturizing repairing foundation make-up emulsion |
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| CN105287242A (en) * | 2015-11-11 | 2016-02-03 | 浙江元研生物科技有限公司 | Skin care product containing human stem cell growth factor and preparation method thereof |
| CN105727264A (en) * | 2016-03-24 | 2016-07-06 | 松原市颖奇经贸有限责任公司 | Scar repair liquid and preparation method thereof |
| CN105919860A (en) * | 2016-05-04 | 2016-09-07 | 福建春伦茶业集团有限公司 | Jasmine flower soothing gel |
| CN105997776A (en) * | 2016-05-10 | 2016-10-12 | 四川美咖生物科技有限公司 | Mask liquid with repairing function and preparation method thereof |
| CN105919838A (en) * | 2016-06-14 | 2016-09-07 | 成都舒乐科技发展有限公司 | Skin care cosmetic product and preparation method |
| CN106138521A (en) * | 2016-06-28 | 2016-11-23 | 郑州雷曼药业有限公司 | A kind of cicatrix repairs gel and preparation method thereof |
| CN107028830B (en) * | 2017-04-25 | 2021-03-09 | 徐子雁 | Medicine for preventing scar hyperplasia and preparation process thereof |
| CN107028830A (en) * | 2017-04-25 | 2017-08-11 | 徐子雁 | It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia |
| CN107184425A (en) * | 2017-07-25 | 2017-09-22 | 广州铭心化妆品有限公司 | A kind of moisturizing essence and preparation method thereof |
| CN107648591A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair emulsion and preparation method thereof |
| CN107648590A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair composition and its preparation and application |
| CN107837205A (en) * | 2017-11-28 | 2018-03-27 | 苏州汇涵医用科技发展有限公司 | The preparation method of skin repair facial mask |
| CN107648589A (en) * | 2017-11-28 | 2018-02-02 | 苏州汇涵医用科技发展有限公司 | A kind of skin repair gel and preparation method thereof |
| CN110227044A (en) * | 2019-05-12 | 2019-09-13 | 广州芊舟生物科技有限公司 | A kind of HA collagen stoste and preparation method thereof |
| CN111643716A (en) * | 2020-05-26 | 2020-09-11 | 海南芬森医疗器械有限公司 | Scar nursing dressing and preparation method thereof |
| CN111643716B (en) * | 2020-05-26 | 2022-02-15 | 海南芬森医疗器械有限公司 | Scar nursing dressing and preparation method thereof |
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Application publication date: 20150603 |
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