CN104663704B - One kind contains the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes - Google Patents
One kind contains the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes Download PDFInfo
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- CN104663704B CN104663704B CN201310608474.XA CN201310608474A CN104663704B CN 104663704 B CN104663704 B CN 104663704B CN 201310608474 A CN201310608474 A CN 201310608474A CN 104663704 B CN104663704 B CN 104663704B
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Abstract
The invention belongs to field of pesticides, is related to one kind and contains the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes.Composition contains two kinds of active components of A, B, and the ratio of weight and number between component A and the components of component B two is 1:99~99:1 active component A is selected from the chemical compounds I shown in following structural formula, and active component B is selected from mitochondria atriphos（ATP）Synthetase inhibitors class acaricide；The active component A structure is as follows, and composition of the invention has the advantages that synergy is obvious, delaying drug resistance, available for preventing and treating various pests.
Description
Technical field
The invention belongs to field of pesticides, is related to one kind and contains the acaricidal Insecticiding-miticiding group of ATP synthetase inhibitors classes
Compound.
Background technology
Insecticide has obvious effect in terms of preventing and treating agriculture and forestry injurious insect or urban health insect.
Chinese invention patent CN101875633 discloses a kind of pyrazolyl acrylonitrile compound and its control insect pest and mite
Harmful purposes, wherein compound 5（Hereinafter referred to as chemical compounds I）Available for preventing and treating various pests, evil mite, especially have to evil mite prominent
The prevention effect gone out.
Insecticide containing single-activity component, is used continuously in control of insect, easily insect is developed immunity to drugs.It is logical
The insecticide for crossing two kinds of active components is compounded into blending ingredients by a certain percentage, can often improve preventive effect, reduces active ingredient
Dosage, it is cost-effective, while the generation of pest resistance to insecticide can be delayed.
Although generally disclose in the prior art chemical compounds I or its homologue can be produced with other Mixture Use of Insecticides it is additional
The advantages of and effect, but the technical scheme of the binary pesticide composition containing chemical compounds I has no specific disclosure.
The content of the invention
Present invention aims at exploitation one kind to contain the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes, with
Meet increasingly to improve insecticide effect in terms of agricultural and urban health field pest control and the needs of kind is constantly updated.
To achieve the above object, the technical solution adopted by the present invention is：
A kind of composition, composition contain two kinds of active components of A, B, the parts by weight between component A and the components of component B two
Than for 1:99-99:1 active component A is selected from the chemical compounds I shown in following structural formula, and active component B is selected from the phosphorus of mitochondria three
Adenosine monophosphate（ATP）Synthetase inhibitors class acaricide；
Described chemical compounds I has following structure：
The active component B includes propargite (Propargite), tetradiphon (Tetradifon), diafenthiuron
(Diafenthiuron), azacyclotin (Azocyclotin), plictran (Cyhexatin) or fenbutatin oxide (Fenbutatin
) or Aramite oxide.
Active component B is preferably propargite, azacyclotin or diafenthiuron in the composition of the present invention.
The ratio of weight and number of two kinds of active components is 1 in the composition of the present invention:99-99:1, preferably 1:20-20:1,
Further it is optimized for 1:19-19:1.
The composition of the present invention can be in that finished product preparation form provides.Therefore, present invention additionally comprises a kind of dosage form
Insecticides.Using composition as active component, be made as needed missible oil, suspending agent, water-dispersible granules, aqueous emulsion,
Soluble concentrate, wettable powder, water dispersible oil suspending agent etc..The cumulative amount of the active component of composition exists in preparation
Between 0.5%-95%, preferably cumulative amount is between 1%-85%.The content of active component depends on single in the composition of the present invention
Amount of application when solely using, also depends on mixed ratio and synergistic effect degree.The optimum range of active component content is according to combination
The preparation type of thing and it is different.
The preparation of the composition finished product preparation of the present invention can be prepared by common processing method, i.e., by active material and liquid
Carrier（Solvent）Or after solid carrier mixing, add one or more of surfactants such as emulsifying agent, dispersant, wetting agent, viscous
Mixture, stabilizer and defoamer etc..Contain at least one carrier and at least one surfactant in usual composition.Various
In the case of, it should be ensured that present composition active component is uniformly distributed.
Missible oil usually contains 10~50% active component, 2~20% emulsifying agents, and 0~20% other additives are for example stablized
Agent, bleeding agent etc., and solvent（Also contain cosolvent if necessary）.
Suspending agent generally needs to be sanded, to obtain stable non-deposited flowable product.Usually contain 5 in suspending agent~
75% active component, 5~15% dispersants, 4~10% antifreezing agents, 0~10% other additives such as defoamer, preservative, stably
Agent, bleeding agent and thickener, and liquid-carrier surplus.
Water-dispersible granules are usually made 10~100 international standard sieve mesh（1.676~0.152mm）Particle, it can pass through
It is prepared by extruding, dipping or Spray granulation method.Usual water-dispersible granules contain 0.5~75% active component and 5~20%
Surfactant such as stabilizer, wetting dispersing agent, disintegrant and adhesive, and inert carrier surplus.
Wettable powder usually contains 10~85% active component, in addition to solid inert carrier, usually contains 3~10%
Dispersant, can also containing 0~10% stabilizer and（Or）Other additives, such as bleeding agent or sticker.
Aqueous emulsion is to mix to form oil phase by active compound, organic solvent, surfactant；Water, antifreezing agent are mixed,
Into homogeneous aqueous phase.With high-shear emulsion machine high speed shear oil phase, while aqueous phase is slowly added into oil phase, usual active ingredient
1~60%, surfactant 5~20%, antifreezing agent 2~10%, water surplus.
Microemulsion is to mix active compound, organic solvent, surfactant, water, into homogeneous aqueous phase.Generally have
Imitate composition 1~50%, surfactant 10~40%, antifreezing agent 2~10%, water surplus.
Soluble liquid is to mix active component, organic solvent, surfactant, into transparent and homogeneous liquid.
Usual active ingredient 1~50%, surfactant 6~20%, organic solvent surplus.
Water dispersible oil suspending agent is that active component, surfactant, oil based vehicle are added in sand mill and be sanded, until grain
Footpath is qualified, usual active ingredient 2~60%, surfactant 6~20%, oil based vehicle surplus.
Aqueous dispersion liquid and emulsion（Missible oil, wettable powder or concentrate as the present invention is diluted with water obtain
Composition）It is also within the scope of the invention.Above-mentioned emulsion can be water-in-oil type or oil-in-water type, can have thick
Paste-like consistency.
The preparation of the composition finished product preparation of the present invention can use well known to those skilled in the art（Liquid is solid
Body）Carrier and various auxiliary agents.Such as include but is not limited to following all kinds of materials.
Suitable liquid-carrier or solvent can be water, various aromatic hydrocarbons, aliphatic hydrocarbon, ketone, ethers etc., such as toluene, diformazan
Benzene, acetone, cyclohexanone, acetonitrile, benzene, hexamethylene, isopropanol, ethylene glycol, sorbierite, methanol, ethanol, butanol, dimethyl formyl
Amine, dimethyl sulfoxide (DMSO), N- methyl-pyrrolidons, tributyl phosphate, methyl iso-butyl ketone (MIBK), naphthalane, machine oil, petroleum ether, oleic acid first
One or more in ester, methylated soya oil or the molten fiber of methyl etc..The mixture of different liquids is often what is be applicable.
Suitable solid carrier includes natural or synthesis clay and silicate, includes suitable for the solid carrier of pulvis
The white carbon that naturally occurs, rock dust, chalk, quartz, clay, montmorillonite, silica, diatomite, float stone, gypsum, cunning
Stone, bentonite, kaolin, attapulgite, precipitated calcium carbonate, clay and the mineral matter ground of synthesis（Such as microdispersed silicic acid
Or aluminum oxide）.Suitable particulate vector includes broken and classification natural rock such as calcite, marble, float stone, Hai Pao
Stone and dolomite and the synthesis particle made of the powder of organic matter and inorganic matter.
Suitable co-solvents are methanol, phenol, isoamyl alcohol, dimethyl sulfoxide (DMSO), ethyl acetate, butanone, dimethylformamide, two
One or more in methyl sulfoxide, N- methyl-pyrrolidons, methyl oleate, methyl iso-butyl ketone (MIBK), the molten fiber of methyl etc..
Suitable emulsifying agent can be diphenyl phenolic group polyoxyethylene (n18) ether formaldehyde condensation products, ethoxylated castor oil, poly-
Oxygen ethene (n20) phenethyl phenolic group oleic acid ester, alkylaryl polyoxyethylene poly-oxygen propylene aether, alkylaryl formaldehyde resin polyoxy
The different thionic acid calcium of vinethene, oleic acid, agriculture breast AEO-3, agriculture breast AEO-3, agriculture breast 0201B, agriculture breast 0203B, agriculture breast T-20, agriculture breast T-
85th, agriculture breast S-80, agriculture breast 507#, agriculture breast 100#, agriculture breast 36#, agriculture breast 500#, agriculture breast 600#, Nongru-700 #, agriculture breast 1601#, agriculture
Newborn 2201#, agriculture breast NP-7, agriculture breast NP-10, agriculture breast NP-15 etc..
Suitable dispersant can be sodium lignin sulfonate, calcium lignosulfonate, the sodium salt of alkyl naphthalene sulfonic acid condensation polymer, naphthalene
Sodium sulfonate formaldehyde condensation products, methyl naphthalene sulfonate formaldehyde condensate, alkyl-diethylene glycol ether-sodium sulfonate, N- methyl-oleoyls-
Sodium taurocholate, methanonaphthalene sodium sulfonate, oleic acid methylaminoethyl sodium sulfonate, epoxidized polyether, to tertbutyl ether, piperonyl fourth
Ether, alkyl amide taurate, dibutyl naphthalenesulfonic acid formaldehyde condensation products, alkylphenol-polyethenoxy based phosphates etc..
Suitable wetting agent can be lauryl sodium sulfate, sodium sulphate, Morwet EFW, isopropyl naphthalene sulfonate, alkane
Base alcohol polyoxyethylene groups ether sodium sulfate, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, sldium lauryl sulfate, methylene
Sodium naphthalene sulfonate, neopelex, calcium dodecyl benzene sulfonate, Negel aliphatic alcohol polyethenoxy base ether, alkane
Base phenol polyethenoxy base ether etc..
Suitable thickener can be synthesis（Such as carbonyl methylol alcohol, polyvinyl alcohol, polyvinyl acetate）Or natural water
Soluble polymer（Such as xanthans, gelatin, gum arabic, polyvinylpyrrolidone, aluminium-magnesium silicate, polyvinyl alcohol, poly- second two
Alcohol, phenolic resin, shellac, methylcellulose, carboxymethyl cellulose, sodium alginate and soluble starch etc.）, with powder, particle
Or latex form is added in preparation.
Suitable defoamer is bubble enemy, silicone, C8-10 fatty alcohols, phosphoric acid ester, C10-20 saturated fat acids（Such as
Capric acid）And acid amides etc..
Suitable adhesive can be polyvinyl alcohol, polyvinyl acetate, xanthans, gelatin, carboxymethyl cellulose and sea
Mosanom etc..
Aerosol can be made during for preventing and treating city insect, it is necessary to add propellant wherein, bait formulation can also be made
Composition, in addition to containing active component, also containing one or more foodstuffs for being suitable to insect's food-taking, optional attractant and
Optional wetting agent.
Present invention additionally comprises the purposes that the present composition is prepared into Insecticiding-miticiding preparation control agriculture and forestry injurious insect.Specifically, fit
Together in prevent and treat a variety of important agricultural pests for example blister mite, cotton Tetranychus cinnabarinus, vegetables tetranychid, tetranychus viennensis, panonychus citri,
Phyllocoptruta oleivora, apple tetranychus, Tetranychus urticae, goitre mite, flour mite etc., city insect such as termite, blattaria, ant, flies, mosquito class etc..
For Cereal such as wheat, rice etc., beans such as soybean, Kidney bean etc., industrial crops such as cotton, beet, sugarcane etc., fruit tree such as apple
Fruit, pears, citrus, lichee etc., vegetables such as wild cabbage, cauliflower, Chinese cabbage, rape, tomato, capsicum and flowers etc..For preventing and treating city
During city insect, it can be used for family, various public places, office space, and trees etc..
Present invention additionally comprises a kind of method for controlling insect pest, can impose on the present composition with effective dose needs to control
Insect or its growth medium on.The more suitable effective dose generally selected is 10 grams to 500 grams of per hectare, preferably effectively
Dosage is 15 grams to 100 grams of per hectare.
Through indoor biological determination of activity shows that the composition of the present invention has synergistic effect.For example, chemical compounds I with gram
Mite is special, azacyclotin or diafenthiuron are 1:20-20:Good synergistic effect, while compound are shown in the range of 1 to Tetranychus cinnabarinus
I with propargite, azacyclotin or diafenthiuron 19:1-1:More preferable synergistic effect is shown in the range of 19 to Tetranychus cinnabarinus.
The invention has the advantages that：
1. the composition of the present invention shows obvious synergistic effect in certain ratio range, the compound pair is improved
The prevention effect of insect.
2. the present composition reduces the dosage of compound in the application, so as to reduce use cost, environment is reduced
Pollution.
It is anti-with it the problem of in the absence of cross resistance 3. the mechanism of action of each active ingredient is different in the present composition
The generation of pest resistance to insecticide can be delayed by controlling insect, and improve the prevention effect of antagonism population.
Embodiment
Specific examples below is used to the present invention be further described, but the present invention is only limitted to absolutely not these examples.It is real
Each component percentage composition or proportioning in example is applied to be by weight.Active component in each formula is calculated with effective content, while group
The available usual manner of each material prepares in compound.
Formulation Example
The preparation of embodiment 1,20% propargite chemical compounds I missible oil
By recipe requirements, respectively by 18 parts of propargites, 2 parts of chemical compounds Is, 8 parts of agriculture breast 2201#, 2 parts of agriculture breast 1601#, 2 parts
Agriculture breast 600#, 5 parts of methanol, dimethylbenzene are complemented in 100% addition mixing kettle, are uniformly mixed, are heated if necessary with hot bath
Dissolving, you can obtain 20% propargite chemical compounds I missible oil.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 2,20%Aramite chemical compounds I missible oil
By recipe requirements, respectively by 2 parts of Aramite, 18 parts of chemical compounds Is, 6 parts of agriculture breast 0201B, 2 parts of agriculture breast NP-15,4 parts
Agriculture breast 600#, 5 parts of methanol, dimethylbenzene are complemented in 100% addition mixing kettle, are uniformly mixed, are heated if necessary with hot bath
Dissolving, you can obtain 20%Aramite chemical compounds I missible oil.
Can also be by the mitochondria atriphos described by Aramite alternative costs specifications（ATP）Synthesize enzyme level
One kind in agent class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 3,10% tetradiphon chemical compounds I missible oil
By recipe requirements, respectively by 5 parts of tetradiphons, 5 parts of chemical compounds Is, 5 parts of agriculture breast 507#, 3 parts of agriculture breast 0201B, 3
Part agriculture breast 600#, 2 parts of Nongru-700 #, 8 parts of dimethylformamides, dimethylbenzene are complemented in 100% addition mixing kettle, are stirred, mixing
Uniformly, dissolved by heating if necessary with hot bath, you can obtain 10% tetradiphon chemical compounds I missible oil.
Can also be by the mitochondria atriphos described by tetradiphon alternative costs specification（ATP）Synzyme presses down
One kind in preparation class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 4,40% propargite chemical compounds I wettable powder
By recipe requirements, by 36 parts of propargites, 4 parts of chemical compounds Is, 2 parts of lauryl sodium sulfate, 6 parts of methyl naphthalene sulfonic acid sodium
Formaldehyde condensation products, 4 parts of methanonaphthalene sodium sulfonates, 5 parts of White Carbon blacks, precipitated calcium carbonate complement to 100% and are sufficiently mixed, through superfine powder
After broken machine crushes, you can obtain 40% propargite chemical compounds I wettable powder.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 5,30% azacyclotin chemical compounds I wettable powder
By recipe requirements, by 15 parts of azacyclotins, 15 parts of chemical compounds Is, 2 parts of lauryl sodium sulfate, 6 parts of naphthalenesulfonateformaldehyde formaldehyde contractings
Compound, 5 parts of sodium lignin sulfonates, sodium salt, 5 parts of White Carbon blacks, the precipitated calcium carbonates of 3 parts of alkyl naphthalene sulfonic acid condensation polymers complement to 100%
It is sufficiently mixed, after ultra-fine pulverizer disintegrating, you can obtain 30% azacyclotin chemical compounds I wettable powder.
Can also be by the mitochondria atriphos described by azacyclotin alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 6,10% diafenthiuron chemical compounds I wettable powder
By recipe requirements, by 1 part of diafenthiuron, 9 parts of chemical compounds Is, 2 parts of lauryl sodium sulfate, 6 parts of methyl naphthalene sulfonic acid sodium first
Aldehyde condensate, 4 parts of calcium lignosulfonates, 5 parts of dibutyl naphthalenesulfonic acid formaldehyde condensation products, 6 parts of White Carbon blacks, precipitated calcium carbonates complement to
100% is sufficiently mixed, after ultra-fine pulverizer disintegrating, you can obtains 10% diafenthiuron chemical compounds I wettable powder.
Can also be by the mitochondria atriphos described by diafenthiuron alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 7,20% azacyclotin chemical compounds I aqueous emulsion
By recipe requirements, by 2 parts of azacyclotins, 18 parts of chemical compounds Is, 6 parts of polyoxyethylene (n20) phenethyl phenolic group ether oil acid
Ester, 5 parts of agriculture breast 2201#, 2 parts of alkyl-diethylene glycol ether-sodium sulfonates, 10 parts of dimethylformamides, 5 parts of dimethylbenzene add mixing
In kettle, it is stirred, makes to be dissolved into homogeneous oil phase, under high velocity agitation, by excess water（Complement to 100%）Oil phase is added to, i.e.,
It can obtain 20% azacyclotin chemical compounds I of favorable dispersibility.
Can also be by the mitochondria atriphos described by azacyclotin alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
The preparation of embodiment 8,10% diafenthiuron chemical compounds I aqueous emulsion
By recipe requirements, by 2.5 parts of diafenthiurons, 7.5 parts of chemical compounds Is, 5 parts of alkylaryl formaldehyde resin APEOs, 5
Part calcium dodecyl benzene sulfonate, 5 parts of agriculture breast 0201B, 5 parts of cyclohexanone, 5 parts of dimethylbenzene are added in mixing kettles, are stirred, are made molten
Solution is into homogeneous oil phase, under high velocity agitation, by excess water（Complement to 100%）It is added to oil phase, you can obtain favorable dispersibility
10% diafenthiuron chemical compounds I aqueous emulsion aqueous emulsion.
Can also be by the mitochondria atriphos described by diafenthiuron alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new missible oil of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 8,60% propargite chemical compounds I water-dispersible granules
By recipe requirements, by 30 parts of propargites, 30 parts of chemical compounds Is, 7 parts of methyl naphthalene sulfonate formaldehyde condensates, 3 parts it is wooden
Plain sodium sulfonate, sodium salt, 5 parts of cornstarch, 2 parts of epoxidized polyethers, 5 parts of sodium sulphate, the bentonite of 5 parts of alkyl naphthalene sulfonic acid condensation polymers are mended
Foot is added together to 100%, carries out co-grinding, then through plus after water mediates, add and be equipped with the comminutor of certain specification screen cloth
Row is granulated.Then again through drying, screening (pressing screen cloth scope), you can obtain 60% propargite chemical compounds I water-dispersible granules.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water-dispersible granules of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 9,20% azacyclotin chemical compounds I water-dispersible granules
By recipe requirements, by 5 parts of azacyclotins, 15 parts of chemical compounds Is, 2 parts of methanonaphthalene sodium sulfonates, 5 parts of naphthalene sulfonate formaldehydes
Condensation product, the sodium salt of 6 alkyl naphthalene sulfonic acid condensation polymers, 1 part of polyvinylpyrrolidone, 3 parts of soluble starches, diatomite complement to
100% is added together, and carries out co-grinding, then after adding water to mediate, adds in the comminutor equipped with certain specification screen cloth and made
Grain.Then again through drying, screening (pressing screen cloth scope), you can obtain 20% azacyclotin chemical compounds I water-dispersible granules.
Can also be by the mitochondria atriphos described by azacyclotin alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water-dispersible granules of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 10,20% diafenthiuron chemical compounds I water-dispersible granules
By recipe requirements, by 1 part of diafenthiuron, 19 parts of chemical compounds Is, 5 parts of methyl naphthalene sulfonate formaldehyde condensates, 8 parts of alkyl
The sodium salt of naphthalene sulfonic acids condensation polymer, 3 parts of N- methyl-oleoyl-sodium taurocholates, 5 portions of soluble starches, 15 parts of sodium sulphate, bentonites
Complement to 100% to be added together, carry out co-grinding, then after adding water to mediate, add in the comminutor equipped with certain specification screen cloth
It is granulated.Then again through drying, screening (pressing screen cloth scope), you can obtain 20% diafenthiuron chemical compounds I water dispersible grain
Agent.
Can also be by the mitochondria atriphos described by diafenthiuron alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water-dispersible granules of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 11,20% propargite chemical compounds I suspending agent
By recipe requirements, by 18 parts of propargites, 2 parts of chemical compounds Is, 2 parts of agriculture breast 1601#, 4 parts of agriculture breast 0201B, 2 parts of alkyl
The sodium salt of naphthalene sulfonic acids condensation polymer, 0.2 part of xanthans, 0.6 part of white carbon, 5 parts of ethylene glycol, with water 100% is complemented to, sequentially added
Mixed into blending tank, first pass through high shear and carry out coarse crushing, homogenize, be then pumped into sand mill and carry out fine grinding, use granularity
The granularity of material is sanded in distribution instrument detection, after particle diameter reaches standard requirement, filtering, you can obtain 20% propargite chemical compounds I
Suspending agent.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Example 12,10% diafenthiuron chemical compounds I suspending agent
By recipe requirements, by 1 part of diafenthiuron, 9 parts of chemical compounds Is, 5 parts of agriculture breast 0203B, 3 parts of methyl naphthalene sulfonic acid sodium formaldehyde contractings
Compound, 2 parts of agriculture breast 1601#, 2 parts of Nongru-700 #, 0.2 part of xanthans, 0.8 part of white carbon, 5 parts of ethylene glycol, water complement to 100%,
It is added sequentially to mix in blending tank, first passes through high shear and carry out coarse crushing, homogenize, be then pumped into sand mill and carry out carefully
Mill, the granularity that material is sanded is detected with particles distribution instrument, after particle diameter reaches standard requirement, filtering, you can obtain 10% butyl ether
The suspending agent of carbamide compound I.
Can also be by the mitochondria atriphos described by diafenthiuron alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Example 13,50% azacyclotin chemical compounds I suspending agent
By recipe requirements, by 25 parts of azacyclotins, 25 parts of chemical compounds Is, 4 parts of agriculture breast NP-7,2 parts of agriculture breast T-20,2 parts of agriculture breasts
1601#, 4 parts of agriculture breast 0203B, 0.1 part of xanthans, 0.2 part of white carbon, 5 parts of ethylene glycol, water complement to 100%, are added sequentially to
Mixed in blending tank, first pass through high shear and carry out coarse crushing, homogenize, be then pumped into sand mill and carry out fine grinding, with granularity point
The granularity of material is sanded in the detection of cloth instrument, after particle diameter reaches standard requirement, filtering, you can obtain 50% azacyclotin chemical compounds I and hang
Floating agent.
Can also be by the mitochondria atriphos described by azacyclotin alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 14,20% propargite chemical compounds I microemulsion
By recipe requirements, by 5 parts of propargites, 15 parts of chemical compounds Is, 8 parts of diphenyl phenolic group polyoxyethylene (n18) ether formaldehyde contractings
Compound, 5 parts of agriculture breast 2201#, 5 parts of agriculture breast 0201B, 10 parts of dimethyl sulfoxide (DMSO)s, 10 parts of cyclohexanone are added together, and make to be dissolved into uniformly
Oil phase, surplus complement to 100% with water, under high velocity agitation, aqueous phase are added into oil phase or oil phase is added into aqueous phase, are formed
20% propargite chemical compounds I microemulsion of favorable dispersibility.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new microemulsion of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 15,20% propargite chemical compounds I soluble concentrate
By recipe requirements, by 2 parts of propargites, 18 parts of chemical compounds Is, the different thionic acid calcium of 10 parts of oleic acid, 5 parts of agriculture breast 100#, 8 parts
Agriculture breast 2201#, 10 parts of dimethylformamides, 5 parts of methanol, 15 parts of dimethyl sulfoxide (DMSO)s, that the molten fiber of methyl complements to 100% mixing is equal
It is even, dissolved by heating if necessary with hot bath, 20% propargite chemical compounds I soluble concentrate can be made.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new soluble concentrate of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 16,20% propargite chemical compounds I water dispersible oil suspending agent
By recipe requirements, by 10 parts of propargites, 10 parts of chemical compounds Is, 5 parts of agriculture breast 0201B, 3 parts of agriculture breast 500#, 2 parts of agriculture breasts
S-80,2 parts of agriculture breast 1601#, 10 parts of methyl oleates, 3 parts of white carbons, complement to 100% with methylated soya oil and be added sequentially to mix
Close and mixed in tank, first pass through high shear and carry out coarse crushing, homogenize, be then pumped into sand mill and carry out fine grinding, use size distribution
The granularity of material is sanded in instrument detection, after particle diameter reaches standard requirement, filtering, you can obtain 20% propargite chemical compounds I moisture
Dissipate property oil suspending agent.
Can also be by the mitochondria atriphos described by propargite alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water dispersible oil suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 17,20% plictran chemical compounds I water dispersible oil suspending agent
By recipe requirements, by 15 parts of plictrans, 5 parts of chemical compounds Is, 6 parts of agriculture breast 0201B, 3 parts of agriculture breast T-85,2 parts of agriculture breast S-
80th, 2 parts of agriculture breast 1601#, 3 parts of white carbons, complement to 100% with methylated soya oil and be added sequentially to mix in blending tank, first pass through
Cross high shear to carry out coarse crushing, homogenize, be then pumped into sand mill and carry out fine grinding, detected with particles distribution instrument and material is sanded
Granularity, after particle diameter reaches standard requirement, filtering, you can obtain 20% plictran chemical compounds I water dispersible oil suspending agent.
Can also be by the mitochondria atriphos described by plictran alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water dispersible oil suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Embodiment 18,20% fenbutatin oxide chemical compounds I water dispersible oil suspending agent
By recipe requirements, by 19 parts of fenbutatin oxides, 1 part of chemical compounds I, 5 parts of agriculture breast 0201B, 5 parts of agriculture breast NP-15,3 parts of agriculture breasts
S-80,3 parts of agriculture breast AEO-3,10 parts of methyl oleates, 2 parts of white carbons, methylated soya oil complement to 100% and are added sequentially to mix
Mixed in tank, first pass through high shear and carry out coarse crushing, homogenize, be then pumped into sand mill and carry out fine grinding, use particles distribution instrument
The granularity of material is sanded in detection, after particle diameter reaches standard requirement, filtering, you can obtain 20% fenbutatin oxide chemical compounds I moisture and dissipate
Property oil suspending agent.
Can also be by the mitochondria atriphos described by fenbutatin oxide alternative costs specification（ATP）Synthetase inhibitors
One kind in class acaricide, form the new water dispersible oil suspending agent of 20%ATP synthetase inhibitors classes acaricide compound I.
Indoor biological determination of activity
Synergism determination of composition of the embodiment 19 containing chemical compounds I to Tetranychus cinnabarinus
For trying object：Tetranychus cinnabarinus（Tetranychus cinnabarinus Boisduval）, into mite, indoor feeding
Sensitive strain.
Test condition：Temperature：24~26 DEG C, humidity：RH60%, illumination：L:D=14:10
Test method：Using pot-spraying method.The potted plant Kidney bean seedling of sizing of hot-house culture（2 true leaves）, a piece of true leaf is stayed,
Mite 40-60 heads are connected into thereon.Examination material is handled with decoction using Airbrush spray-on processes, dried in the shade naturally.Blank control is first handled,
Then aforesaid operations are repeated from low to high according to experimental design dosage, often handle 4 repetitions.Test worm after processing is placed in
In observation ward, routine observation test worm response situation, number of dead and live insects is investigated after 72h, calculate the death rate.
Evaluation uses Bliss methods, and this method is one of classical way for evaluating mixture effect.Bliss proposes according to it
Independent joint action concept thinks, theoretical death rate P during Mixture Use of Insecticides can be calculated with following formula：
P=Pm+Pn(1-Pm)
PmFor the death rate of the first active component target when concentration is m（%）；PnIt is n for the second active component concentration
When target the death rate（%）.
If the actual of two kinds of active component targets after being mixed with finite concentration is more than theoretical death rate P,
Judge that two kinds of active components are used in mixed way with synergistic effect in the case where setting concentration, it is on the contrary then be antagonism.
It the results are shown in Table 1.
3 kinds of medicaments such as the chemical compounds I of table 1 and propargite are used in mixed way the synergism determination to Tetranychus cinnabarinus into mite
3 medicaments such as the chemical compounds I of embodiment 20 and propargite are used in mixed way to Tetranychus cinnabarinus toxicity determination test
For trying object：Tetranychus cinnabarinus（Tetranychus cinnabarinus Boisduval）, into mite, indoor feeding
Sensitive strain.
Test condition：Temperature：24~26 DEG C, humidity：RH60%, illumination：L:D=14:10
Test medication liquid making method：Reagent agent is accurately weighed respectively with electronic analytical balance, respectively by two kinds of active compounds
After addition proper amount of acetone is completely dissolved, required concentration mother liquor is configured to the water containing 0.1% Tween 80, by two kinds of active ingredient mothers
Liquid is hybridly prepared into mixed solution by a certain percentage, is diluted to the serial medicine of tool finite concentration gradient respectively by experimental design dosage
Liquid.
Test method：Using pot-spraying method.The potted plant Kidney bean seedling of sizing of hot-house culture（2 true leaves）, a piece of true leaf is stayed,
Mite 40-60 heads are connected into thereon.Examination material is handled with decoction using Airbrush spray-on processes, dried in the shade naturally.Blank control is first handled,
Then aforesaid operations are repeated from low to high according to experimental design dosage, often handle 4 repetitions.Test worm after processing is placed in
In observation ward, routine observation test worm response situation, number of dead and live insects is investigated after 72h, calculate the death rate.
Corrected mortality is calculated with Abbott formula, appliance computer program is obtained each mixed for examination single dose and variant proportioning
Virulence regression equation, LC50Value and 95% confidence limit, with Sun Yunpei (Sun Y-P) method, obtain the mixed common poison of each proportioning
Coefficient, evaluated.If co-toxicity coefficient is summation action close to 100, hence it is evident that is synergistic effect higher than 100, hence it is evident that be less than 100
Antagonism.
Result of the test is shown in Table 2, table 3 and table 4.As can be seen from the table, chemical compounds I and propargite, azacyclotin are each for trying
Proportioning is mixed to show synergistic effect to Tetranychus cinnabarinus, and chemical compounds I is with diafenthiuron with 20:1~3:Used with 1 ratio to cinnabar leaf
Mite has synergistic effect.
Table 2：Chemical compounds I propargite is to joint toxicity measuring result in Tetranychus cinnabarinus room
Table 3：Chemical compounds I azacyclotin is to joint toxicity measuring result in Tetranychus cinnabarinus room
Table 4：Chemical compounds I diafenthiuron is to joint toxicity measuring result in Tetranychus cinnabarinus room
Claims (6)
1. one kind contains the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes, it is characterised in that：Composition contain A,
Two kinds of active components of B, active component A are selected from the chemical compounds I shown in following structural formula, and the chemical compounds I structure is as follows：
Chemical compounds I；
Active component B is selected from propargite, azacyclotin or diafenthiuron；
The ratio of weight and number of active component A and propargite is 1:20-20:1；
The ratio of weight and number of active component A and azacyclotin is 1:20-20:1；
The ratio of weight and number of active component A and diafenthiuron is 3:1-19:1、1:10、1:5.
2. according to the composition described in claim 1, it is characterised in that：Composition can be configured to missible oil, suspending agent, moisture and dissipate
Property granula, aqueous emulsion, microemulsion, soluble concentrate, wettable powder or water dispersible oil suspending agent.
3. according to the composition described in claim 2, it is characterised in that：The cumulative amount of active component is in 0.5%- in composition
Between 95%.
4. according to the composition described in claim 3, it is characterised in that：The cumulative amount of active component is in 1%-85% in composition
Between.
5. a kind of contain the acaricidal insecticide acaricide composition application of ATP synthetase inhibitors classes according to described in claim 1,
It is characterized in that：The composition is used to prepare insecticidal/acaricidal agent, for controlling agriculture and forestry injurious insect or urban health insect.
6. containing the acaricidal insecticide acaricide composition application of ATP synthetase inhibitors classes according to described in claim 5, it is special
Sign is：With effective agent gauge, the composition for being prepared into insecticidal/acaricidal agent is imposed on to the insect for needing to control or its growth
Medium on.
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| CN106605654A (en) * | 2015-10-21 | 2017-05-03 | 陕西韦尔奇作物保护有限公司 | Insecticidal composition containing SYP-9625 |
| CN106605657A (en) * | 2015-10-24 | 2017-05-03 | 陕西韦尔奇作物保护有限公司 | Pesticide combination containing SYP-9625 |
| CN106818808A (en) * | 2017-02-15 | 2017-06-13 | 海南省植物保护总站（海南省农药检定所） | Pesticidal combination containing second azoles mite nitrile and diafenthiuron |
| CN106689137A (en) * | 2017-02-16 | 2017-05-24 | 佛山市瑞生通科技有限公司 | Pesticide composition containing ethyl cyanide and propargite |
| CN106719687A (en) * | 2017-02-16 | 2017-05-31 | 佛山市瑞生通科技有限公司 | A kind of composition pesticide of the mite nitrile of azoles containing second and cyflumetofen |
| CN106937634A (en) * | 2017-03-15 | 2017-07-11 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of acaricide composition and its application method |
| CN106942235A (en) * | 2017-03-21 | 2017-07-14 | 佛山市瑞生通科技有限公司 | A kind of Pesticidal combination containing propylene glycol alginate and second azoles mite nitrile |
| CN108684681B (en) * | 2017-03-31 | 2021-03-30 | 沈阳中化农药化工研发有限公司 | Mite killing preparation and application thereof |
| CN109691451B (en) * | 2017-10-24 | 2021-03-05 | 沈阳中化农药化工研发有限公司 | Insecticidal and acaricidal synergistic composition containing ethacrylonitrile and application thereof |
| CN111657281B (en) * | 2019-03-05 | 2021-10-29 | 沈阳中化农药化工研发有限公司 | Insecticidal and acaricidal composition |
| CN114190387A (en) * | 2020-09-18 | 2022-03-18 | 浙江省化工研究院有限公司 | Acaricide composition |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101875633A (en) * | 2009-04-29 | 2010-11-03 | 中国中化股份有限公司 | Pyrazolyl acrylonitrile compound and application thereof |
| CN102438987A (en) * | 2009-05-22 | 2012-05-02 | 日产化学工业株式会社 | Crystals of cyenopyrafen and its preparation methods |
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| CN101875633A (en) * | 2009-04-29 | 2010-11-03 | 中国中化股份有限公司 | Pyrazolyl acrylonitrile compound and application thereof |
| CN102438987A (en) * | 2009-05-22 | 2012-05-02 | 日产化学工业株式会社 | Crystals of cyenopyrafen and its preparation methods |
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