CN104662209B - 使用高电场制造纳米孔 - Google Patents

使用高电场制造纳米孔 Download PDF

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Publication number
CN104662209B
CN104662209B CN201380036177.0A CN201380036177A CN104662209B CN 104662209 B CN104662209 B CN 104662209B CN 201380036177 A CN201380036177 A CN 201380036177A CN 104662209 B CN104662209 B CN 104662209B
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membrane
potential
fluid
reservoirs
current
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Chinese (zh)
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CN104662209A (zh
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W·H·郭
V·塔巴德-科萨
K·A·Z·布里格斯
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University of Ottawa
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University of Ottawa
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    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25F—PROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F3/00—Electrolytic etching or polishing
    • C25F3/02—Etching
    • C25F3/14—Etching locally
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/009—After-treatment of organic or inorganic membranes with wave-energy, particle-radiation or plasma
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00087—Holes
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25F—PROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F7/00—Constructional parts, or assemblies thereof, of cells for electrolytic removal of material from objects; Servicing or operating
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B7/00—Measuring arrangements characterised by the use of electric or magnetic techniques
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0095—Semiconductive materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/22—Electrical effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/42—Details of membrane preparation apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/0282—Dynamic pores-stimuli responsive membranes, e.g. thermoresponsive or pH-responsive
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0353—Holes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Electrochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Biophysics (AREA)
  • Plasma & Fusion (AREA)
  • Nanotechnology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Steroid Compounds (AREA)
  • Testing Of Short-Circuits, Discontinuities, Leakage, Or Incorrect Line Connections (AREA)
CN201380036177.0A 2012-05-07 2013-05-07 使用高电场制造纳米孔 Active CN104662209B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261643651P 2012-05-07 2012-05-07
US61/643,651 2012-05-07
US201361781081P 2013-03-14 2013-03-14
US61/781,081 2013-03-14
PCT/IB2013/000891 WO2013167955A1 (en) 2012-05-07 2013-05-07 Fabrication of nanopores using high electric fields

Publications (2)

Publication Number Publication Date
CN104662209A CN104662209A (zh) 2015-05-27
CN104662209B true CN104662209B (zh) 2017-03-15

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CN201380036177.0A Active CN104662209B (zh) 2012-05-07 2013-05-07 使用高电场制造纳米孔
CN201380036310.2A Active CN104411386B (zh) 2012-05-07 2013-05-07 用于控制固态纳米孔的大小的方法

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CN201380036310.2A Active CN104411386B (zh) 2012-05-07 2013-05-07 用于控制固态纳米孔的大小的方法

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US (2) US9777389B2 (https=)
EP (2) EP2847367B1 (https=)
JP (3) JP6420236B2 (https=)
KR (2) KR102065745B1 (https=)
CN (2) CN104662209B (https=)
AU (2) AU2013257756B2 (https=)
BR (2) BR112014027873B8 (https=)
CA (2) CA2872602C (https=)
ES (2) ES2630064T3 (https=)
MX (2) MX353370B (https=)
SG (3) SG11201407249XA (https=)
WO (2) WO2013167952A1 (https=)

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JP6209122B2 (ja) * 2014-04-02 2017-10-04 株式会社日立ハイテクノロジーズ 孔形成方法及び測定装置
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SG10201906952QA (en) * 2014-12-19 2019-09-27 Univ Ottawa Integrating nanopore sensors within microfluidic channel arrays using controlled breakdown
SG11201706587TA (en) 2015-02-24 2017-09-28 Univ Ottawa Localizing nanopore fabrication on a membrane by laser illumination during controlled breakdown
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CN109791138B (zh) * 2016-10-12 2021-01-08 豪夫迈·罗氏有限公司 纳米孔电压方法
WO2018105123A1 (ja) * 2016-12-09 2018-06-14 株式会社日立ハイテクノロジーズ ナノポア形成方法、ナノポア形成装置及び生体分子計測装置
JP6877466B2 (ja) * 2017-01-10 2021-05-26 株式会社日立ハイテク ナノポアを用いた電流計測装置及び電流計測方法
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CN110741093A (zh) 2017-04-28 2020-01-31 渥太华大学 控制通过纳米孔的分子的移位
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JP6975609B2 (ja) * 2017-10-19 2021-12-01 株式会社日立製作所 親水性保持基材、計測装置、デバイスおよび親水性保持方法
WO2019109253A1 (zh) * 2017-12-05 2019-06-13 清华大学 调控固态纳米孔系统中固态纳米孔有效尺寸的方法
JP6959121B2 (ja) * 2017-12-05 2021-11-02 株式会社日立ハイテク 孔形成方法及び孔形成装置
CN108279312B (zh) * 2018-03-08 2021-06-01 冯建东 一种基于纳米孔的蛋白质组学分析装置及血清检测方法及应用
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JP7543174B2 (ja) * 2021-03-03 2024-09-02 株式会社日立製作所 ポア形成方法、およびポア形成装置
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Also Published As

Publication number Publication date
CN104411386A (zh) 2015-03-11
JP2015525114A (ja) 2015-09-03
EP2847367A1 (en) 2015-03-18
CA2872600C (en) 2021-11-23
CA2872600A1 (en) 2013-11-14
KR20150040799A (ko) 2015-04-15
ES2629952T3 (es) 2017-08-16
MX353370B (es) 2018-01-09
AU2013257756B2 (en) 2017-05-04
AU2013257759A1 (en) 2014-11-27
EP2847367A4 (en) 2016-01-13
WO2013167952A1 (en) 2013-11-14
AU2013257756A1 (en) 2014-11-27
CN104662209A (zh) 2015-05-27
SG10201606334XA (en) 2016-09-29
ES2630064T3 (es) 2017-08-17
CA2872602A1 (en) 2013-11-14
BR112014027829A2 (pt) 2017-06-27
BR112014027873A2 (pt) 2017-06-27
KR102065745B1 (ko) 2020-01-14
EP2846901B1 (en) 2017-03-29
EP2846901A4 (en) 2016-01-13
SG11201407249XA (en) 2014-12-30
KR20150037748A (ko) 2015-04-08
CA2872602C (en) 2020-08-25
MX357200B (es) 2018-06-29
EP2846901A1 (en) 2015-03-18
US9777390B2 (en) 2017-10-03
CN104411386B (zh) 2016-10-12
MX2014013412A (es) 2016-04-07
JP6298450B2 (ja) 2018-03-20
EP2847367B1 (en) 2017-03-29
BR112014027873B1 (pt) 2021-05-25
KR102065754B1 (ko) 2020-02-11
US20150108008A1 (en) 2015-04-23
SG11201407252UA (en) 2014-12-30
US9777389B2 (en) 2017-10-03
BR112014027873B8 (pt) 2021-11-03
JP2015517401A (ja) 2015-06-22
MX2014013410A (es) 2015-12-08
JP2018187626A (ja) 2018-11-29
JP6420236B2 (ja) 2018-11-07
AU2013257759B2 (en) 2017-07-13
BR112014027829B1 (pt) 2021-03-23
WO2013167955A1 (en) 2013-11-14
US20150109008A1 (en) 2015-04-23

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