CN104640551A - 造血区室的增强的重建和自动重建 - Google Patents

造血区室的增强的重建和自动重建 Download PDF

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Publication number
CN104640551A
CN104640551A CN201380048261.4A CN201380048261A CN104640551A CN 104640551 A CN104640551 A CN 104640551A CN 201380048261 A CN201380048261 A CN 201380048261A CN 104640551 A CN104640551 A CN 104640551A
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myc
bcl
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B·C·特纳
Y·里菲利
G·A·伯德
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Taiga Biotechnologies Inc
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Taiga Biotechnologies Inc
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Priority to CN202210288576.7A priority Critical patent/CN114645015A/zh
Priority to CN201910848417.6A priority patent/CN110643576A/zh
Publication of CN104640551A publication Critical patent/CN104640551A/zh
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    • A61K38/1761—Apoptosis related proteins, e.g. Apoptotic protease-activating factor-1 (APAF-1), Bax, Bax-inhibitory protein(s)(BI; bax-I), Myeloid cell leukemia associated protein (MCL-1), Inhibitor of apoptosis [IAP] or Bcl-2
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    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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CN201380048261.4A 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建 Pending CN104640551A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202210288576.7A CN114645015A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建
CN201910848417.6A CN110643576A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261674224P 2012-07-20 2012-07-20
US61/674,224 2012-07-20
US201361785691P 2013-03-14 2013-03-14
US61/785,691 2013-03-14
PCT/US2013/051384 WO2014015312A1 (en) 2012-07-20 2013-07-19 Enhanced reconstitution and autoreconstitution of the hematopoietic compartment

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN202210288576.7A Division CN114645015A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建
CN201910848417.6A Division CN110643576A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建

Publications (1)

Publication Number Publication Date
CN104640551A true CN104640551A (zh) 2015-05-20

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Application Number Title Priority Date Filing Date
CN201380048261.4A Pending CN104640551A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建
CN202210288576.7A Pending CN114645015A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建
CN201910848417.6A Pending CN110643576A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建

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CN202210288576.7A Pending CN114645015A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建
CN201910848417.6A Pending CN110643576A (zh) 2012-07-20 2013-07-19 造血区室的增强的重建和自动重建

Country Status (11)

Country Link
US (4) US9789135B2 (https=)
EP (2) EP3868387A1 (https=)
JP (5) JP6285930B2 (https=)
CN (3) CN104640551A (https=)
AU (3) AU2013292330B2 (https=)
CA (2) CA3133302A1 (https=)
DK (1) DK2877189T3 (https=)
ES (1) ES2856179T3 (https=)
IL (3) IL236763B (https=)
SG (2) SG11201500429QA (https=)
WO (1) WO2014015312A1 (https=)

Cited By (4)

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CN110177758A (zh) * 2016-12-02 2019-08-27 泰加生物工艺学公司 纳米颗粒调配物
CN113874033A (zh) * 2019-04-08 2021-12-31 泰加生物工艺学公司 用于冷冻保存免疫细胞的组合物和方法
US12370217B2 (en) 2019-05-14 2025-07-29 Htyr Acquisition Llc Compositions and methods for treating T cell exhaustion
US12496341B2 (en) 2008-08-28 2025-12-16 Htyr Acquisition Llc Methods for reducing anergy in lymphocytes using modulators of MYC

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KR101441843B1 (ko) 2005-10-18 2014-09-17 내셔날 쥬이쉬 헬스 조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및 사용 방법
EP2285832B1 (en) 2008-05-16 2020-08-26 Taiga Biotechnologies, Inc. Antibodies and processes for preparing the same
JP6285930B2 (ja) * 2012-07-20 2018-02-28 タイガ バイオテクノロジーズ，インク． 造血コンパートメントの再構築及び自家再構築の増進
US10272115B2 (en) 2013-03-11 2019-04-30 Taiga Biotechnologies, Inc. Production and use of red blood cells
US9816074B2 (en) 2014-07-25 2017-11-14 Sangamo Therapeutics, Inc. Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
HUE055583T2 (hu) 2014-09-16 2021-12-28 Sangamo Therapeutics Inc Eljárások és készítmények nukleáz által közvetített genommódosításhoz és -javításhoz hematopoetikus õssejtekben
EP3224617A1 (en) * 2014-11-26 2017-10-04 Oxford University Innovation Limited Detection of acute myeloid leukaemia (aml) leukaemic stem cells (lsc)
EP3595683A1 (en) * 2017-03-15 2020-01-22 Orca Biosystems, Inc. Compositions and methods for hematopoietic stem cell transplants
US10149898B2 (en) 2017-08-03 2018-12-11 Taiga Biotechnologies, Inc. Methods and compositions for the treatment of melanoma
US20200155600A1 (en) * 2017-08-03 2020-05-21 Taiga Biotechnologies, Inc. Methods and compositions for the treatment of cancer
WO2024077145A1 (en) * 2022-10-05 2024-04-11 Garuda Therapeutics, Inc. Modified hematopoietic stem cells and progenies thereof

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