CN104524222A - Traditional Chinese medicine for promoting wound healing - Google Patents
Traditional Chinese medicine for promoting wound healing Download PDFInfo
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- CN104524222A CN104524222A CN201510024243.3A CN201510024243A CN104524222A CN 104524222 A CN104524222 A CN 104524222A CN 201510024243 A CN201510024243 A CN 201510024243A CN 104524222 A CN104524222 A CN 104524222A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for promoting wound healing. The traditional Chinese medicine is prepared from the following traditional Chinese medicines: saxifraga stolonifera, rhizoma bletillae, cinnamomum camphora leaves, purslane, moutan bark, common cephalanoplos herb, astragalus membranaceus and borneol. Preferably, the traditional Chinese medicine is prepared from the following traditional Chinese medicines in parts by weight: 200-400 parts of saxifraga stolonifera, 200-400 parts of rhizoma bletillae, 100-400 parts of cinnamomum camphora leaves, 50-200 parts of purslane, 50-200 parts of moutan bark, 50-200 parts of common cephalanoplos herb, 50-200 parts of astragalus membranaceus and 10-50 parts of borneol. Compared with the traditional treatment method, the traditional Chinese medicine for promoting wound healing has more obvious effects of stopping bleeding, relieving pain and reducing swelling, has obvious effects of antibiosis, bacteriostasis, necrotic tissue removal and granulation promotion, and has the advantages which the traditional medicines do not have.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine promoting wound healing and preparation method thereof.
Background technology
Wound is the function and integrity division organized in health.Operation is the important means of disease therapy and wound clinically, simultaneously in some vehicle accidents, often causes the skin and flesh wound of people serious, needs hemostatic suture wound as early as possible.Therefore promotion wound healing, the medicine of control wound infection, always by surgeon is favored.
Su Anping (brief talking the effect of the many repair in trauma of external treatment with Chinese medicine, " the Gansu traditional Chinese medical science ", 2006,19 (4) .1) thinks that wound infection is the major obstacle of tissue repair, and traumatic wounds all inevitably has various germ contamination wound.Body, to the in-house various antibacterial early reaction of intrusion, has nothing to do with pathogen type, but time infection often betides extreme imbalance between Abwehrkraft des Koepers and the microorganism species of intrusion.When wound generation infection is right, the extracellular toxin be secreted when microorganism is in vital movement process with destruction in wound not only causes erythrocyte and hematoblastic destruction, but also make thin vessels smooth muscle contraction, spasm, cause blood capillary to block and local tissue necrosis.Moreover, the comprehensive function of a large amount of bacterial exotoxin, endotoxin and proteolytic enzyme after wound, and biological effect and the radical damage of cytokine is caused by their cytotoxicity, cause tissue edema, hemorrhage, purulent secretion quantity increase, protein is lost in a large number by wound surface sharply to be increased with electrolyte, in the granulation tissue of suppurative wound, albumen is hydrolyzed in a large number, antibacterial invades surrounding tissue in a large number, the hyperplasia that chamber or granulation tissue are hindered in granulation tissue growth filling affects epithelium formation, affects the speed of repair in trauma.For wound infection, at present clinically mainly with application antibiotic be preventive means.
Treatment by Chinese herbs wound with a long history, tradition applies several thousand, for the people solves the pain of injury.At present, the Chinese medicine compound for wound has YUNNAN BAIYAO, pink powder, SHENGJINDAO POWDER etc.
Summary of the invention
The object of the present invention is to provide the Chinese medicine that a kind of promotion wound healing newly prevents wound infection.
The present invention adopts following technical scheme to achieve these goals: a kind of Chinese medicine promoting wound healing, it is characterized in that being prepared from by following Chinese crude drug: Herba Saxifragae, Pseudobulbus Bletillae (Rhizoma Bletillae), Folium cinnamomi camphorae, Herba Portulacae, Cortex Moutan, Herba Cirsii, the Radix Astragali, Borneolum Syntheticum.
Particularly, the present invention promotes the Chinese medicine of wound healing, it is characterized in that being prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 200-400, Pseudobulbus Bletillae (Rhizoma Bletillae) 200-400, Folium cinnamomi camphorae 100-400, Herba Portulacae 50-200, Cortex Moutan 50-200, Herba Cirsii 50-200, Radix Astragali 50-200, Borneolum Syntheticum 10-50.
Can preferably, the present invention promotes the Chinese medicine of wound healing, it is characterized in that being prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 300, Pseudobulbus Bletillae (Rhizoma Bletillae) 300, Folium cinnamomi camphorae 180, Herba Portulacae 100, Cortex Moutan 120, Herba Cirsii 100, the Radix Astragali 100, Borneolum Syntheticum 40.
Also can preferably, the present invention promotes the Chinese medicine of wound healing, it is characterized in that being prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 400, Pseudobulbus Bletillae (Rhizoma Bletillae) 300, Folium cinnamomi camphorae 300, Herba Portulacae 120, Cortex Moutan 155, Herba Cirsii 180, the Radix Astragali 180, Borneolum Syntheticum 50.
Can also preferably, the present invention promotes the Chinese medicine of wound healing, it is characterized in that being prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 240, Pseudobulbus Bletillae (Rhizoma Bletillae) 400, Folium cinnamomi camphorae 160, Herba Portulacae 50, Cortex Moutan 80, Herba Cirsii 200, the Radix Astragali 200, Borneolum Syntheticum 10.
According to Chinese medical theory, in prescription of the present invention:
Herba Saxifragae: record its nature and flavor according to " China's book on Chinese herbal medicine " bitter; Pungent; Cold; Slightly poisonous; Return through lung; Spleen; Large intestine channel.Dispelling wind; Heat clearing away; Removing pathogenic heat from blood and toxic substance from the body.Main air heat cough, lung abscess, spits blood, acute toothache, rubella pruritus, carbuncle erysipelas, swelling and pain of hemorrhoid, insect-bite, traumatic hemorrhage.
Pseudobulbus Bletillae (Rhizoma Bletillae): record its nature and flavor according to " China's book on Chinese herbal medicine " bitter; Sweet; Puckery; Cold.Return lung; Stomach warp.Astringing to arrest bleeding; Detumescence and promoting granulation.Main spitting of blood; Spit blood; Epistaxis; Have blood in stool; Traumatic hemorrhage; Carbuncle pyogenic infections from tumour or sore; Scald and burn; Rhagadia manus et pedis; Anal fissure
Folium cinnamomi camphorae: record its nature and flavor according to " China's book on Chinese herbal medicine " pungent; Temperature.GUIXIN; Spleen; Lung meridian.Dispel the wind; Dehumidifying; Removing toxic substances; Parasite killing.Main air pain of dampness syndrome; Stomachache; Burn due to hot liquid or fire; Sore swollen toxin; Chronic ulcer of the lower limb; Scabies; Skin pruritus; Insect-bite.
Herba Portulacae: record its nature and flavor acid according to " China's book on Chinese herbal medicine "; Cold in nature.Return large intestine; Liver Channel.Heat-clearing and toxic substances removing; Eliminating pathogenic heat from blood to cure dysentery; Dehumidify treating stranguria.Main pyretic toxicity dysentery; Pyretic stranguria; Urine retention; Leucorrhea with red and white discharge; Metrorrhagia; Hemorrhoidal bleeding; Skin infection carbuncle furuncle; Erysipelas; Scrofula; Exudative dermatitis; Bald in vain.
Cortex Moutan: record its nature and flavor according to " China's book on Chinese herbal medicine " bitter, pungent, be slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Herba Cirsii: record its nature and flavor according to " China's book on Chinese herbal medicine " sweet; Micro-hardship; Cool in nature.Return liver; Spleen channel.Cooling blood for hemostasis; Clearing heat for detumescence.Main hemoptysis; Spit blood; Epistaxis; Hematuria; Stranguria with blood; Have blood in stool; Dysentery; Metrorrhagia and metrostaxis; Traumatic hemorrhage; Swollen ulcer drug
The Radix Astragali: record its nature and flavor according to " Chinese Pharmacopoeia " sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Borneolum Syntheticum: record its nature and flavor according to " Chinese Pharmacopoeia " pungent, bitter, be slightly cold.GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Through clinical experiment checking, the present invention promotes that the Chinese medicine of wound healing is compared with traditional therapy, and its hemostasis, pain relieving, detumescence effect are more obvious, and the effect of bacteriostasis antibiosis, removing the necrotic tissue and promoting granulation is better, has the advantage not available for conventional medicament.In side, Pseudobulbus Bletillae (Rhizoma Bletillae), Folium cinnamomi camphorae, Herba Portulacae, Cortex Moutan, Herba Cirsii, the Radix Astragali, Borneolum Syntheticum can be worked in coordination with mutually, and gain is complementary, both can stop blooding, pain relieving, detumescence, again can be antibacterial, antibacterial, thus prevent wound infection, accelerating wound healing, shortens the hospital stays of patient.
Present invention also offers a kind of preparation method promoting the Chinese powder medicine of wound healing, it is characterized in that, comprise concrete preparation process as follows:
(1) get Herba Saxifragae, Pseudobulbus Bletillae (Rhizoma Bletillae), Folium cinnamomi camphorae, Herba Portulacae, Cortex Moutan, Herba Cirsii, the Radix Astragali, Borneolum Syntheticum respectively, drying and crushing, cross 100-200 mesh sieve.
(2) by the Chinese crude drug mixing after above-mentioned pulverizing, sterilizing, bottling, obtains powder of the present invention.
Certainly, Chinese medicine of the present invention can adopt conventional preparation process to be prepared into powder, unguentum, oil preparation etc.
Visible the present invention promotes that the preparation technique of traditional Chinese medicine of wound healing is simple.The invention of the proved of clinical experiment simultaneously has astringing to arrest bleeding, reducing swelling and alleviating pain, antimicrobial antiphlogistic, and wound healing is fast, and the features such as preventing from scar, have obvious economic and social benefit.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but should be understood that, this is not limitation of the present invention.
Embodiment 1:
(1) get Herba Saxifragae 300g, Pseudobulbus Bletillae (Rhizoma Bletillae) 300g, Folium cinnamomi camphorae 180g, Herba Portulacae 100g, Cortex Moutan 120g, Herba Cirsii 100g, Radix Astragali 100g, Borneolum Syntheticum 40g respectively, drying and crushing, cross 200 mesh sieves.
(2) by the Chinese crude drug mixing after above-mentioned pulverizing, sterilizing, bottling, obtains powder of the present invention.
Embodiment 2:
(1) get Herba Saxifragae 400g, Pseudobulbus Bletillae (Rhizoma Bletillae) 300g, Folium cinnamomi camphorae 300g, Herba Portulacae 120g, Cortex Moutan 155g, Herba Cirsii 180g, Radix Astragali 180g, Borneolum Syntheticum 50g respectively, drying and crushing, cross 150 mesh sieves.
(2) by the Chinese crude drug mixing after above-mentioned pulverizing, sterilizing, bottling, obtains powder of the present invention.
Embodiment 3:
(1) get Herba Saxifragae 240g, Pseudobulbus Bletillae (Rhizoma Bletillae) 400g, Folium cinnamomi camphorae 160g, Herba Portulacae 50g, Cortex Moutan 80g, Herba Cirsii 200g, Radix Astragali 200g, Borneolum Syntheticum 10g respectively, drying and crushing, cross 100 mesh sieves.
(2) by the Chinese crude drug mixing after above-mentioned pulverizing, sterilizing, bottling, obtains powder of the present invention.
Embodiment 4:
(1) get 280g, Pseudobulbus Bletillae (Rhizoma Bletillae) 400g, Folium cinnamomi camphorae 400g, Herba Portulacae 200g, Cortex Moutan 200g, Herba Cirsii 200g, Radix Astragali 100g, Borneolum Syntheticum 50g respectively, drying and crushing, cross 150 mesh sieves.
(2) by the Chinese crude drug mixing after above-mentioned pulverizing, sterilizing, bottling, obtains powder of the present invention.
Clinical data:
1. physical data
Get in November ,-2014 in January, 2013 because of traumatic wound to our hospital patient 200 example, be divided into two groups at random: experimental group 150 example, 6 years old-72 years old age, 32 years old mean age.Wound length is less than 5cm person 92 example, and wound length is greater than 5cm person 58 example, and wound depth is person 96 example within 0.5cm, and wound depth is in 0.5cm-1.0cm person 54 example.Matched group 50 example, 5 years old-70 years old age, 32 years old mean age.Wound length is less than 5cm person 31 example, and wound length is greater than 5cm person 19 example, and wound depth is person 32 example within 0.5cm, and wound depth is in 0.5cm-1.0cm person 18 example.Above patient all bleeds because wound causes open wound, pain is gone to a doctor, and two groups of patient ages, wound classification, damage location, sewing needle number, wound degrees etc. compare, through X
2inspection, there was no significant difference (P > 0.05).
2. Therapeutic Method:
Experimental group: after traumatic wound debridement and suturing, the powder embodiment of the present invention 1 prepared is sprinkling upon on wound equably, and thickness is advisable with 1mm-2mm, wrapping.Change dressings every day 1 time, until wound healing is taken out stitches.
Matched group: operate by traumatic wound nursing routine, after wound debridement and suturing, applies alcohol gauze, changes common aseptic medical dressing every day 1 time, until wound healing is taken out stitches.
3. experimental result:
3.1 liang of group hemostasis, detumescence, analgesic effects compare in table 1.
Table 1 liang group therapeutic effect
| Group | Number | Bleeding stopping period (h) | Swelling time (h) | Analgesic time (h) |
| Experimental group | 150 | 0.6±0.9 @ | 30.2±14.4 # | 19.5±12.8 * |
| Matched group | 50 | 2.8±1.5 | 121.2±20.3 | 72.1±20.5 |
Note:
@, #, *all represent through X 2 test, p < 0.01.
The bleeding stopping period of visible test group, swelling time and analgesic time all have pole significant difference compared with matched group.
3.2 liang of group wound infections, wound healing situations compare in table 2.
Table 2 liang group wound infection, wound healing situation
| Group | Number | Wound infection | The healing of I phase | The healing of II phase |
| Experimental group | 150 | 0 | 145 | 5 |
| Matched group | 50 | 10 | 30 | 10 |
The healing of I phase refers to that tissue repair is based on original cell, and only containing a small amount of fibrous tissue, local is without infecting, and hematoma or necrosis, tissue regeneration processes is rapid, and 26S Proteasome Structure and Function reparation is good.
The healing of II phase refers to that tissue defect is large, edge of wound is not whole, trembles out, cannot be neatly involutory, or with the healing of the wound infected.
Show from table 2 experimental result, test group occurs without wound infection, and I phase healing rate can reach 96.7%, and matched group has 10 examples that wound infection occurs, and I phase healing rate is 60%.Meanwhile, experimental group patient only has individually slight cicatrix after healing, rarely has cicatrix to produce.And matched group generally leaves cicatrix, some patients leaves obvious cicatrix.
Above experimental result shows that the present invention promotes that the Chinese medicine of wound healing stops blooding, pain relieving, detumescence effect are more obvious, and the effect of bacteriostasis antibiosis, removing the necrotic tissue and promoting granulation is better, has the advantage not available for conventional medicament.
Claims (5)
1. promote a Chinese medicine for wound healing, it is characterized in that, be prepared from by following Chinese crude drug: Herba Saxifragae, Pseudobulbus Bletillae (Rhizoma Bletillae), Folium cinnamomi camphorae, Herba Portulacae, Cortex Moutan, Herba Cirsii, the Radix Astragali, Borneolum Syntheticum.
2. the Chinese medicine promoting wound healing as claimed in claim 1, is characterized in that, be prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 200-400, Pseudobulbus Bletillae (Rhizoma Bletillae) 200-400, Folium cinnamomi camphorae 100-400, Herba Portulacae 50-200, Cortex Moutan 50-200, Herba Cirsii 50-200, Radix Astragali 50-200, Borneolum Syntheticum 10-50.
3. the Chinese medicine of the promotion wound healing as described in claim 1-2, is characterized in that, is prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 300, Pseudobulbus Bletillae (Rhizoma Bletillae) 300, Folium cinnamomi camphorae 180, Herba Portulacae 100, Cortex Moutan 120, Herba Cirsii 100, the Radix Astragali 100, Borneolum Syntheticum 40.
4. the Chinese medicine of the promotion wound healing as described in claim 1-3, is characterized in that, is prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 400, Pseudobulbus Bletillae (Rhizoma Bletillae) 300, Folium cinnamomi camphorae 300, Herba Portulacae 120, Cortex Moutan 155, Herba Cirsii 180, the Radix Astragali 180, Borneolum Syntheticum 50.
5. the Chinese medicine of the promotion wound healing as described in claim 1-4, is characterized in that, is prepared from by the Chinese crude drug of following weight portion:
Herba Saxifragae 240, Pseudobulbus Bletillae (Rhizoma Bletillae) 400, Folium cinnamomi camphorae 160, Herba Portulacae 50, Cortex Moutan 80, Herba Cirsii 200, the Radix Astragali 200, Borneolum Syntheticum 10.
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| CN105560620A (en) * | 2015-12-25 | 2016-05-11 | 马真真 | Trauma treatment traditional Chinese medicine preparation |
| CN109771568A (en) * | 2019-02-22 | 2019-05-21 | 南阳南石医院 | A kind of biological agent and preparation method for inhibiting scar and promoting wound healing |
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| CN109771568A (en) * | 2019-02-22 | 2019-05-21 | 南阳南石医院 | A kind of biological agent and preparation method for inhibiting scar and promoting wound healing |
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