CN104225258B - A kind of Chinese medicine composition promoting wound healing - Google Patents
A kind of Chinese medicine composition promoting wound healing Download PDFInfo
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- CN104225258B CN104225258B CN201410529706.7A CN201410529706A CN104225258B CN 104225258 B CN104225258 B CN 104225258B CN 201410529706 A CN201410529706 A CN 201410529706A CN 104225258 B CN104225258 B CN 104225258B
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Abstract
The invention discloses a kind of Chinese medicine composition promoting wound healing and preparation method thereof, relate to technical field of Chinese medicines, it is prepared from by Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati and Semen Sesami wet goods 10 taste raw material.Pharmaceutical composition of the present invention has reducing swelling and alleviating pain, bactericidal antiphlogistic, expelling pus and promoting granulation, control wound infection, and wound healing time is short, the advantage of control scar hyperplasia.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition promoting wound healing.
Background technology
Traumatic wound is one of urgency, the modal wound of outpatient service, and the infection of traumatic wound is one of modal infection in hospital infection.The operative incision low-grade infection of surgical site infections can cause otch delayed healing, and increase patient pain, operative incision severe infection then may cause disruption of wound that systemic infection even can be caused to injure life.The traditional Chinese medical science thinks that wound infection is the wet fire of diseases caused by exogenous pathogenic factor character and conduct, and instant heating is stopped up poly-, damp-heat and virulent fire produced from the interior, or because of the liver spleen heat in blood double anger stagnation of QI, causes airsetting stagnant, and passages through which vital energy circulates is stopped up resistance and formed.Modern existing wound processing method or process medicine, processing procedure is loaded down with trivial details, and wound healing is slow, and after healing, majority can leave serious cicatrix, affects attractive in appearance, especially at outward appearance positions such as faces.
Summary of the invention
In view of the deficiencies in the prior art, the object of the present invention is to provide a kind of for Chinese medicine composition promoting wound healing and preparation method thereof.Pharmaceutical composition of the present invention has reducing swelling and alleviating pain, bactericidal antiphlogistic, expelling pus and promoting granulation, control wound infection, and wound healing time is short, the advantage of control scar hyperplasia.
The present invention promotes the Chinese medicine composition of wound healing, is prepared from by following medical material: Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati and Oleum sesami.
Present invention also offers the weight of above-mentioned ingredients:
Pseudobulbus Bletillae (Rhizoma Bletillae) 20-60 part, Rhizoma Polygoni Cuspidati 20-60 part, Lignum Dalbergiae Odoriferae 12-40 part, Radix Paeoniae Rubra 12-30 part, Radix Astragali 16-38 part, Herba Cirsii 6-18 part, Exocarpium Benincasae 6-20 part, Pericarpium Citri Reticulatae Viride 4-40 part, Pericarpium Granati 4-40 part, Oleum sesami 200-1000 part.
As preferably, the weight of ingredients of the present invention is:
Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Rhizoma Polygoni Cuspidati 40 parts, Lignum Dalbergiae Odoriferae 36 parts, Radix Paeoniae Rubra 30 parts, the Radix Astragali 18 parts, Herba Cirsii 12, Exocarpium Benincasae 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 10 parts, Oleum sesami 600 parts.
In the present invention the concocting method of ingredients and meridian distribution of property and flavor as follows:
Pseudobulbus Bletillae (Rhizoma Bletillae): [process of preparing Chinese medicine] is cleaned, and runs through, shave, dries.[nature and flavor] are bitter, sweet, puckery, are slightly cold.[return through] returns lung, liver, stomach warp.[function cures mainly] astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Rhizoma Polygoni Cuspidati: [process of preparing Chinese medicine] removing impurity, cleans, runs through, cut sheet, dry.[nature and flavor] micro-hardship, is slightly cold.[return through] returns liver, gallbladder, lung meridian.[function cures mainly] expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Lignum Dalbergiae Odoriferae: [process of preparing Chinese medicine] removing impurity, is split into fritter, is ground into fine powder or pound sheet.[nature and flavor] are pungent, temperature.[return through] returns liver, spleen channel.[function cures mainly] promoting flow of QI and blood, pain relieving, hemostasis.For epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.
Radix Paeoniae Rubra: [process of preparing Chinese medicine] removing impurity, separately size, cleans, run through, cut sheet, dry.[nature and flavor] are bitter, are slightly cold.[return through] returns Liver Channel.[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
The Radix Astragali: [process of preparing Chinese medicine] removing impurity, size separately, is cleaned, run through, cut sheet, dry.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Herba Cirsii: [process of preparing Chinese medicine] is got clean Herba Cirsii section and put in pot, fry to brownish black, note sustainability, spray a little clear water, taking-up is dried.[nature and flavor] sweet, bitter, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] herb: cooling blood for hemostasis, removing blood stasis to reduce swelling.For epistaxis, spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus.Root stock: hepatitis.
Exocarpium Benincasae: [process of preparing Chinese medicine] removing impurity, clean, stripping and slicing or wide silk, dry.[nature and flavor] are sweet, cool.[return through] returns spleen, small intestine meridian.[function cures mainly] inducing diuresis to remove edema.For edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine.
Pericarpium Citri Reticulatae Viride: [process of preparing Chinese medicine] gets Pericarpium Citri Reticulatae Viride sheet or silk, fries to micro-yellow according to stir-baking with vinegar.Every 100kg Pericarpium Citri Reticulatae Viride, uses vinegar 15kg.[nature and flavor] are bitter, pungent, temperature.[return through] returns liver, gallbladder, stomach warp.[function cures mainly] is soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Pericarpium Granati: [process of preparing Chinese medicine] Pericarpium Granati charcoal: get Punica granatum L. skin bit, fries to surperficial blackyellow, inner sepia according to parch to black method.[nature and flavor] are sour, puckery, temperature.[return through] returns large intestine channel.[function cures mainly] relieving diarrhea with astringents, hemostasis, anthelmintic.For chronic diarrhea, chronic dysentery, has blood in stool, proctoptosis, metrorrhagia, leucorrhea, abdominal pain due to worm stagnation.
Oleum sesami: [nature and flavor] are sweet, cool.Effect of [function cures mainly] loosening bowel to relieve constipation, removing toxic substances and promoting granulation.
Pseudobulbus Bletillae (Rhizoma Bletillae) in Chinese medicine composition of the present invention, astringing to arrest bleeding, detumescence and promoting granulation.Rhizoma Polygoni Cuspidati: expelling wind and removing dampness, dissipating blood stasis analgesic therapy.Lignum Dalbergiae Odoriferae: promoting flow of QI and blood, pain relieving, hemostasis.Radix Paeoniae Rubra, clearing away heat and cooling blood, eliminating stasis to stop pain.The Radix Astragali, invigorating QI to consolidate the body surface resistance, expelling pus and promoting granulation.Herba Cirsii: cooling blood for hemostasis, removing blood stasis to reduce swelling.Exocarpium Benincasae, inducing diuresis to remove edema.Pericarpium Citri Reticulatae Viride, soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.Pericarpium Granati, hemostasis, anthelmintic.Oleum sesami, effect of removing toxic substances and promoting granulation, coordinating the actions of various ingredients in a prescription.Above-mentioned medical material can be worked in coordination with mutually, both can cooling blood and relieving pain, dissipating blood stasis for subsidence of swelling, again can anti-inflammation, removing the necrotic tissue and promoting granulation.Namely reach and alleviate patient's pain fast, make wound healing, reach again centre tissue regeneration promoting of dispelling, invigorating blood circulation addiction, more, do not stay the effect of cicatrix.
Preferably, Chinese medicine composition of the present invention can be prepared into exterior-applied formulation.
Described exterior-applied formulation is preferably oil preparation, paste or unguentum.
Another object of the present invention is to provide a kind of preparation method promoting the Chinese medicine composition of wound healing, and it comprises following preparation process:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Herba Cirsii, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively.
(2) Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 7-14 days, are heated to 100 DEG C-130 DEG C with putting sealing immersion in pot, insulation 15-60 minute, is cooled to room temperature.
(3) in step 2) in add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 30-60 minute, sealing soak within 7-14 days, namely obtain Chinese medicine composition oil preparation of the present invention.
Oil preparation using method of the present invention: according to wound size clip oilpaper, by Chinese medicine composition oil preparation uniform application of the present invention above, then flap coverage, changes dressings 1 every day; Or directly smear wound surface with oil preparation of the present invention, every day 3-4 time.Until wound healing or take out stitches.
The present invention promotes the oil preparation of wound healing, determined curative effect, and effective percentage is high, is specially adapted to the patient of wound disunion of a specified duration, has cured all kinds of patient more than 1000 example.
Detailed description of the invention
Below will further illustrate the present invention by specific embodiment; but and do not limit the present invention in any way; but everyly do not depart from technical solution of the present invention content; according to any simple modification, equivalent variations and remodeling that technical spirit of the present invention is done, still belong to the protection domain of technical solution of the present invention.
1. example of formulations:
The preparation of 1.1 Chinese medicine composition oil preparationes of the present invention
Prescription (with parts by weight):
Pseudobulbus Bletillae (Rhizoma Bletillae) 48 parts, Rhizoma Polygoni Cuspidati 48 parts, Lignum Dalbergiae Odoriferae 40 parts, Radix Paeoniae Rubra 30 parts, the Radix Astragali 36 parts, Herba Cirsii 16 parts, Exocarpium Benincasae 18 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 20 parts and Oleum sesami 700 parts.
Preparation method:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively.
(2) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 14 days with putting sealing immersion in pot, to be heated to 110 ± 5 DEG C, to be incubated 45 minutes, to be cooled to room temperature.
(3) in step 2) in add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 60 minutes, sealing immersion within 14 days, namely obtain Chinese medicine composition oil preparation of the present invention.
The preparation of 1.2 Chinese medicine composition oil preparationes of the present invention
Prescription (with parts by weight):
Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Rhizoma Polygoni Cuspidati 40 parts, Lignum Dalbergiae Odoriferae 36 parts, Radix Paeoniae Rubra 30 parts, the Radix Astragali 18 parts, Herba Cirsii 12, Exocarpium Benincasae 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 10 parts, Oleum sesami 600 parts.
Preparation method:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively.
(2) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 14 days with putting sealing immersion in pot, to be heated to 110 ± 5 DEG C, to be incubated 30 minutes, to be cooled to room temperature.
3) in step 2) in add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 30 minutes, sealing immersion within 14 days, namely obtain Chinese medicine composition oil preparation of the present invention.
The preparation of 1.3 Chinese medicine composition oil preparationes of the present invention
Prescription (with parts by weight):
Pseudobulbus Bletillae (Rhizoma Bletillae) 24 parts, Rhizoma Polygoni Cuspidati 30 parts, Lignum Dalbergiae Odoriferae 36 parts, Radix Paeoniae Rubra 12 parts, the Radix Astragali 20 parts, Herba Cirsii 6 parts, Exocarpium Benincasae 6 parts, 6 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 6 parts, Oleum sesami 600 parts.
Preparation method:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively.
(2) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 7 days with putting sealing immersion in pot, to be heated to 110 ± 5 DEG C, to be incubated 30 minutes, to be cooled to room temperature.
3) in step 2) in add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 30 minutes, sealing immersion within 7 days, namely obtain Chinese medicine composition oil preparation of the present invention.
The preparation of 1.4 Chinese medicine composition oil preparationes of the present invention
Prescription (with parts by weight):
Pseudobulbus Bletillae (Rhizoma Bletillae) 28 parts, Rhizoma Polygoni Cuspidati 24 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Paeoniae Rubra 20 parts, the Radix Astragali 16 parts, Herba Cirsii 18 parts, Exocarpium Benincasae 20 parts, 30 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 24 parts, Oleum sesami 600 parts.
Preparation method:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, the Radix Astragali, Herba Cirsii, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively.
(2) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 7 days with putting sealing immersion in pot, to be heated to 110 ± 5 DEG C, to be incubated 30 minutes, to be cooled to room temperature.
3) in step 2) in add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 30 minutes, sealing immersion within 7 days, namely obtain Chinese medicine composition oil preparation of the present invention.
2 clinical laboratory data
2.1 clinical datas:
Choose in July ,-2014 in July, 2011 continuously routine the patient 280 that the court's emergency treatment, outpatient service are medical because of traumatic wound, be divided into experimental group and matched group at random.Experimental group 200 example, 6 years old-74 years old age, 34.1 ± 7.8 years old mean age.Wherein facial wound 38 example, trunk 28 example, extremity 134 example; Wound length is less than 5cm person 154 example, and wound length is greater than 5cm person 46 example, and wound depth is person 163 example within 0.5cm, and wound depth is in 0.5cm-1.0cm person 37 example.Matched group 80 example, 6 years old-72 years old age, 34.8 ± 7.1 years old mean age.Wherein facial wound 15 example, trunk 11 example, extremity 54 example; Wound length is less than 5cm person 63 example, and wound length is greater than 5cm person 17 example, and wound depth is person 64 example within 0.5cm, and wound depth is in 0.5cm-1.0cm person 16 example.Above patient all bleeds because wound causes open wound, pain is gone to a doctor, until recovery from illness.Two groups of Genders, age, wound location, sewing needle number, wound degrees etc. compare, through X
2inspection, there was no significant difference (P > 0.05), has comparability.
2.2 Therapeutic Method:
Experimental group: to traumatic wound debridement or after sewing up, according to wound size clip oilpaper, above being layered on equably by oil preparation obtained for invention formulation embodiment 2, then flap coverage, changes dressings 1 every day; Or directly smear wound surface with oil preparation of the present invention, every day 3-4 time.Until wound healing or take out stitches.
Matched group: to traumatic wound debridement or sew up after, with 5% iodophor disinfection wound surface and surrounding skin, apply alcohol gauze, every day change dressings 1 time.
2.3 experimental results:
2.3.1 two groups of hemostasis, detumescence, analgesic effects compare.
In experimental group after 200 routine patient's wound external application oil preparation of the present invention, can stop blooding rapidly, pain relieving, detumescence, with matched group, there is pole significant difference (see table 1).And experimental group when changing dressings or take out stitches without pain or slightly keenly feel.And matched group patient is at more change dressings or when taking out stitches, and has pain in various degree.
Table 1 liang group therapeutic effect
| Group | Case load | Bleeding stopping period (h) | Swelling time (h) | Analgesic time (h) |
| Experimental group | 200 | 0.3±0.4* | 29.9±14.8* | 12.5±16.7* |
| Matched group | 80 | 2.2±1.5 | 105.4±29.0 | 80.3±20.3 |
Remarks: * represents and compares P < 0.01 with matched group.
2.3.2 two groups of wound infections, wound healing situations compare.
After treatment, none example of experimental group infects, and within average 5 days, take out stitches, I phase healing rate can reach 99%.Matched group is taken out stitches for average 8 days, and I phase healing rate is only 71%, and has 8 routine wounds to infect.Refer to table 2.
Table 2 liang group wound infection, wound healing situation
| Group | Case load | Wound infection | The healing of I phase | The healing of II phase |
| Experimental group | 200 | 0 | 198 | 2 |
| Matched group | 80 | 8 | 57 | 23 |
Note: the healing of I phase refers to that tissue repair is based on original cell, only containing a small amount of fibrous tissue, local is without infecting, and hematoma or necrosis, tissue regeneration processes is rapid, and 26S Proteasome Structure and Function reparation is good.The healing of II phase refers to that tissue defect is large, edge of wound is not whole, trembles out, cannot be neatly involutory, or with the healing of the wound infected.
Visible Chinese medicine composition oil preparation of the present invention, preventing Be very effective in wound infection, contributes to wound healing.In addition, after experimental group patient takes out stitches, continue to smear Chinese medicine composition oil preparation of the present invention after 30 days, have patient's cicatrix of more than 80% to disappear.After treatment group patient takes out stitches one month, patient's cicatrix of 5% is only had to disappear.
Claims (5)
1. promote an external preparation for wound healing, it is characterized in that, be prepared from by the medical material of following weight:
Pseudobulbus Bletillae (Rhizoma Bletillae) 20-60 part, Rhizoma Polygoni Cuspidati 20-60 part, Lignum Dalbergiae Odoriferae 12-40 part, Radix Paeoniae Rubra 12-30 part, Radix Astragali 16-38 part, Herba Cirsii 6-18 part, Exocarpium Benincasae 6-20 part, Pericarpium Citri Reticulatae Viride 4-40 part, Pericarpium Granati 4-40 part, Oleum sesami 200-1000 part.
2. the external preparation promoting wound healing as claimed in claim 1, is characterized in that, be prepared from by the medical material of following weight:
Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Rhizoma Polygoni Cuspidati 40 parts, Lignum Dalbergiae Odoriferae 36 parts, Radix Paeoniae Rubra 30 parts, the Radix Astragali 18 parts, Herba Cirsii 12, Exocarpium Benincasae 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Granati 10 parts, Oleum sesami 600 parts.
3. the external preparation promoting wound healing as claimed in claim 1 or 2, it is characterized in that, described external preparation is paste, oil preparation or unguentum.
4. the external preparation promoting wound healing as claimed in claim 3, it is characterized in that, described external preparation is oil preparation.
5. the external preparation promoting wound healing as claimed in claim 4, it is characterized in that, its preparation method comprises following steps:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Herba Cirsii, Pericarpium Granati, drying and crushing crosses 200 mesh sieves respectively;
(2) Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygoni Cuspidati, Lignum Dalbergiae Odoriferae, Radix Paeoniae Rubra, Exocarpium Benincasae, Pericarpium Citri Reticulatae Viride and Oleum sesami after 7-14 days, are heated to 100 DEG C-130 DEG C with putting sealing immersion in pot, insulation 15-60 minute, is down to room temperature;
(3) in step (2), add the Radix Astragali, Herba Cirsii, Pericarpium Granati, stir after 30-60 minute, sealing is soaked and is namely obtained oil preparation in 7-14 days.
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| CN105726962A (en) * | 2016-02-29 | 2016-07-06 | 山东大学第二医院 | Traditional Chinese medicine composition for promoting wound healing and preparation method thereof |
| CN109771568A (en) * | 2019-02-22 | 2019-05-21 | 南阳南石医院 | A kind of biological agent and preparation method for inhibiting scar and promoting wound healing |
| CN112057568B (en) * | 2020-10-26 | 2021-11-09 | 复旦大学附属金山医院 | Traditional Chinese medicine composition for treating infantile anal fissure and application thereof |
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