CN104488870B - A kind of composition pesticide containing bromothalonil - Google Patents
A kind of composition pesticide containing bromothalonil Download PDFInfo
- Publication number
- CN104488870B CN104488870B CN201410817460.3A CN201410817460A CN104488870B CN 104488870 B CN104488870 B CN 104488870B CN 201410817460 A CN201410817460 A CN 201410817460A CN 104488870 B CN104488870 B CN 104488870B
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- CN
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- Prior art keywords
- bromothalonil
- kasugarnycin
- agent
- disease
- composition pesticide
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- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- PVTHJAPFENJVNC-MHRBZPPQSA-N kasugamycin Chemical compound N[C@H]1C[C@H](NC(=N)C(O)=O)[C@@H](C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O PVTHJAPFENJVNC-MHRBZPPQSA-N 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 125000006353 oxyethylene group Chemical group 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000005056 polyisocyanate Substances 0.000 description 1
- 229920001228 polyisocyanate Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- JHJUUEHSAZXEEO-UHFFFAOYSA-M sodium;4-dodecylbenzenesulfonate Chemical compound [Na+].CCCCCCCCCCCCC1=CC=C(S([O-])(=O)=O)C=C1 JHJUUEHSAZXEEO-UHFFFAOYSA-M 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of composition pesticide containing bromothalonil, containing bromothalonil and the bactericidal composition of kasugarnycin, and the weight ratio of bromothalonil and kasugarnycin is 1 60～80 1.The present composition has potentiation to the multiple diseases of harm agricultural production, decreases pesticide usage amount, reduces pesticide residual quantity on crop, alleviate environmental pollution, and to person poultry safety, Environmental compatibility is good, and disease is not likely to produce Drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of composition pesticide containing bromothalonil in agriculture
Application in crop pest.
Background technology
Bromothalonil (bromothalonil), bromothalonil is a kind of wide spectrum, low toxicity, mildew-resistant, goes out
Algae antibacterial.Can suppress and root out the growth of antibacterial, fungus and algae, it is adaptable to textile,
The anticorrosions such as leather, mildew-resistant, water for industrial use algae removal.Corps diseases is had preferable prevention effect,
Especially anthrax there is specially good effect.
Kasugarnycin (kasugamycin), [5-amino-2-methyl-6-(2,3,4,5,6-carbonyl hexamethylenes
Base oxo) pyrans-3-base amino-a-IMDA], kasugarnycin is agricultural antibiotic, has relatively
Strong interior absorption, this medicine mainly disturbs amino acid whose metabolism esterase system, thus affects protein
Synthesis, suppression hyphal elongation and cause cell granulations, but on spore germination without impact.
But, in the real process of agricultural production, the problem that controlling disease is easiest to produce
It it is the generation of disease drug resistance.Different cultivars composition compounds, and is to prevent and treat resistance disease very
Common method.Heterogeneity compounds, and according to practical application effect, judges certain
Compounding be potentiation, add and or antagonism.In most cases, the compounding effect of sterilization
Fruit is all additive effect, really has the compounding little of potentiation, and especially potentiation is non-
Compounding that Chang Mingxian, potentiation ratio are the highest is the most less.Studying through inventor, finding will
Can produce good potentiation after bromothalonil and kasugarnycin are compounding, and about bromothalonil and
The relevant report that kasugarnycin compounds is the openest.
Summary of the invention
The purpose of the present invention is to propose to one and have that synergistic function, use cost be low, preventive effect
The good composition pesticide containing bromothalonil.
The composition pesticide containing bromothalonil that the present invention proposes contains bromothalonil and kasugarnycin, bromine
Bacterium nitrile and kasugarnycin weight ratio are 1 60～80 1, and bromothalonil is the heaviest with kasugarnycin
Amount ratio is 1 40～60 1；The more preferably weight ratio of bromothalonil and kasugarnycin is
1:10～30:1；Most preferably the weight ratio of bromothalonil and kasugarnycin is 1:5～20:1.
The composition pesticide containing bromothalonil that the present invention proposes is for preventing and treating disease on crops
Purposes, described crops include cereal crops, legume crop, fibre crops, sugar crop,
Melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil plant
Crop, flower crop, medicinal crop, crop, green manure pasture crop；Described disease
For epidemic disease, powdery mildew, rust, rust, downy mildew, droop, melasma, banded sclerotial blight,
Spot defoliation, gray mold, ring spot, soft rot, leaf mold, Peptic Ulcers, anthrax,
Bacterial wilt, bacterial angular leaf spot or rice blast.
Bromothalonil, the weight ratio of kasugarnycin are 1 60～80 1.Generally activity in compositions
The weight percentage of component is the 0.5%～90% of gross weight, is preferably 5%～80%.
According to different preparation types, active component content scope is different.Generally, liquid preparation
Containing the active substance of by weight 1%～70%, preferably 5%～50%；Solid preparation
Containing the active substance of by weight 5%～80%, preferably 10%～80%.
The bactericidal composition of the present invention at least contains a kind of surfactant, when being beneficial to use
Active component dispersion in water.Surface-active contents is the 5%～30% of total formulation weight amount,
Surplus is solid or liquid diluent.
The bactericidal composition of the present invention through dilution or directly can be used before use by user.
Its preparation can be prepared by common processing method known in those skilled in the art, will activity
After material mixes with liquid flux or solid carrier, add surfactant such as dispersant, steady
Determine one or more in agent, wetting agent, binding agent, defoamer, disintegrating agent, antifreeze etc..
The bactericidal composition of the present invention, can be processed in any sterilization acceptable dose on demand
Type, the most more preferably dosage form be wettable powder, water dispersible granules, suspending agent, suspension emulsion,
Aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent, water preparation, soluble powder
Agent, it is also possible to make granule, seed coat agent, suspension seed-coating agent, ultra low volume liquids.
Compositions comprises following constituent content when making wettable powder: bromothalonil 0.1%～80%,
Kasugarnycin 0.1%～60%, dispersant 2%～10%, wetting agent 2%～10%, filler surplus.
Compositions includes following constituent content when making water dispersible granules: bromothalonil 0.1%～80%,
Kasugarnycin 0.1%～60%, dispersant 3%～12%, wetting agent 1%～8%, disintegrating agent
1%～10%, binding agent 0～8%, filler surplus.
Compositions includes following constituent content when making suspending agent: bromothalonil 0.1%～50%, spring
Thunder mycin 0.1%～50%, dispersant 2%～10%, wetting agent 2%～10%, defoamer
0.01%～2%, thickening agent 0～2%, antifreeze 0～8%, deionized water add to 100%.
Compositions includes following constituent content when making suspension emulsion: bromothalonil 0.5%～50%, spring
Thunder mycin 0.5%～50%, dispersant 2%～10%, defoamer 0.01%～2%, solvent 1%～15%,
Thickening agent 0～2%, emulsifying agent 2%～12%, antifreeze 0～8%, deionized water add to 100%.
Compositions comprises following constituent content when making aqueous emulsion: bromothalonil 0.5%～50%, spring
Thunder mycin 0.5%～50%, solvent 1%～30%, emulsifying agent 1%～15%, antifreeze 0～8%,
Thickening agent 0～2%, defoamer 0.01%～2%, deionized water supply surplus.
Compositions comprises following constituent content when making microemulsion: bromothalonil 0.5%～50%, spring
Thunder mycin 0.5%～50%, solvent 1%～30%, emulsifying agent 3%～25%, antifreeze 0～8%,
Defoamer 0.01%～2%, deionized water supply surplus.
Compositions includes following constituent content when making microcapsule suspending agent: bromothalonil 0.5%～50%,
Kasugarnycin 0.5%～50%, macromolecule cyst material 2%～10%, dispersant 1%～10%,
Organic solvent 1%～10%, emulsifying agent 1%～7%, defoamer 0.01%～2%, pH adjusting agent
0.01%～5%, deionized water adds to 100%.
Compositions includes following constituent content when making microcapsule suspension-suspendinagent agent: bromothalonil
0.5%～50%, kasugarnycin 0.5%～50%, macromolecule cyst material 2%～10%, dispersant
1%～12%, wetting agent 1%～8%, organic solvent 1%～15%, emulsifying agent 1%～6%, disappear
Infusion 0.01%～2%, thickening agent 0～2%, pH adjusting agent 0.01%～5%, deionized water add
To 100%；
Compositions includes following constituent content when making water preparation: bromothalonil 0.01%～50%, spring
Thunder mycin 0.01%～40%, cosolvent 2%～6%, wetting agent 1%-10%, antifreeze 0～8%,
Deionized water adds to 100%.
Compositions includes following constituent content when making soluble powder: bromothalonil
0.01%～80%, kasugarnycin 0.01%～60%, dispersant 3～12%, wetting agent 1～8%,
Disintegrating agent 1～10%, filler 10～93%.
Described dispersant is selected from alkylnaphthalene sulfonate, the condensation of double (alkyl) naphthalene sulphonate formaldehyde
Thing, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene
Oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, alkylaryl polyoxyethylene ether,
Aliphatic alcohol polyethenoxy base ether, alkylphenol-polyethenoxy phonetic formaldehyde condensation products sulfate, alkylbenzene
Sulfonic acid calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy are phonetic, fatty amine polyoxy
Ethylene is phonetic, polyoxyethylene carboxylate, ester polyoxyethylene phonetic in one or more.
Described wetting agent is selected from: sodium lauryl sulphate, dodecylbenzene sodium sulfonate, pull open
Powder BX, wetting and penetrating agent F, spaonin powder, sodium laurylsulfate, tea seed cake, Bombyx mori L., nothing are suffered from
One or more in sub-powder.
Described disintegrating agent is selected from: sodium bicarbonate, sodium carbonate, bentonite, carbamide, ammonium sulfate,
One or more in glucose, aluminum chloride.
Described binding agent is selected from: hydroxymethyl cellulose, hydroxyethyl cellulose, Magnesiumaluminumsilicate,
Gelatin, guar gum, arabic gum, xanthan gum, sodium tripolyphosphate, phenolic resin, sodium alginate,
White dextrin, methylcellulose, sodium acrylate, polyvinylpyrrolidone, crosslinked polyethylene pyrroles
One or more in alkanone, Polyethylene Glycol, polyvinyl alcohol.
Described antifreeze is selected from: glycerol, ethylene glycol, propylene glycol, glycerol, diethylene glycol,
One or more in 2,2'-ethylenedioxybis(ethanol)., Polyethylene Glycol.
Described defoamer is selected from: silicone, C8～10Aliphatic alcohols, C10～20Satisfied fatty acid
One or more in class (such as capric acid) and amide, silicone oil, silicone compound.
Described emulsifying agent is selected from: agriculture breast 500# (alkyl benzene calcium sulfonate), OP series phosphoric acid
Ester (thermally coupled distillation columns), 600# phosphate ester (phenyl phenol polyoxyethyl ether phosphorus
Acid esters), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salt, three second
Alcohol amine salt, agriculture breast 400# (benzyl dimethyl phenol polyoxyethyl ether), agriculture breast 600# (phenyl phenol
Polyoxyethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxyethyl ether), agriculture breast 36#
(phenethyl fluosite polyoxyethyl ether), agriculture breast 1600# (phenethyl phenol polyoxyethanyl
Polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (nonyl phenol gather
Oxygen vinyl Ether), By series (castor oil polyoxyethylene ether), agriculture breast 33# (alkylaryl polyoxy
Propylene polyoxyethylene ether), agriculture breast 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), span
Series (sorbitan monostearate), TWEEN Series (sorbitan fatty acid ester polyoxy
Vinyl Ether), AEO series (fat alcohol polyoxyethylenated alcohol) in one or more.
Described stabilizer is selected from: BHT, triphenyl phosphite, epoxychloropropane, tricresyl phosphate
One or more in butyl ester, triethanolamine, diethanolamine, ethanolamine.
Described filler is selected from: Kaolin, kieselguhr, bentonite, attapulgite, white carbon,
One or more in starch, precipitated calcium carbonate.
Described macromolecule cyst material is selected from carbamide, formaldehyde, polyisocyanate, polyfunctional group
Acyl halide polyamines, polyfunctional group acyl halide dihydroxylic alcohols, sodium alginate, polyvinyl alcohol, gelatin,
Arabic gum, sucrose, modified starch, maltose, deformation lactoprotein, glycerol, calcium chloride,
One or more in carboxymethyl cellulose, beta-schardinger dextrin-.
Described PH regulator is selected from sodium hydroxide, hydrochloric acid, citric acid, sorbic acid
Plant or multiple.
Described thickening agent is selected from: hydroxymethyl cellulose, hydroxyethyl cellulose, Magnesiumaluminumsilicate,
Gelatin, guar gum, arabic gum, xanthan gum, sodium tripolyphosphate, phenolic resin, sodium alginate,
White dextrin, methylcellulose, sodium acrylate, polyvinylpyrrolidone, crosslinked polyethylene pyrroles
One or more in alkanone, Polyethylene Glycol, polyvinyl alcohol.
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The water preparation the key technical indexes of the present invention:
Soluble powder the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1), after bromothalonil is compounding with kasugarnycin, there is obvious potentiation and lasting effect；(2)
Cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits are made
Thing, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicine
Greater activity is all had by the disease on crop, crop, green manure pasture crop；(3) reduce
Pesticide usage amount, reduces pesticide residual quantity on crop, alleviates environmental pollution；(4)
To person poultry safety, Environmental compatibility is good；And preparation adhesion strength strengthens, resistance of rainwater washing against.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are
Percentage by weight, but the invention is not limited in this.
Application Example one
Embodiment 1～8 wettable powder
Bromothalonil, kasugarnycin, dispersant, wetting agent, filler are mixed in mixed cylinder all
Even, remix uniformly after jet mill is pulverized, can be prepared by wettability of the present invention
Powder product, is specifically shown in Table 1.
Table 1 embodiment 1～8 each component and weight portion
Embodiment 9～12 water dispersible granules
By bromothalonil, kasugarnycin, dispersant, wetting agent, disintegrating agent, filler etc. together warp
Comminution by gas stream obtains the particle diameter needed, and adds other auxiliary agents such as binding agent (can add and can be not added with),
Obtain granulation materials.Through in item is quantitatively sent into fluidized bed granulating dryer and granulation and be dried
After, can be prepared by water dispersible granules product of the present invention, be specifically shown in Table 2.
Table 2 embodiment 9～12 each component and weight portion
Embodiment 13～16 suspending agent
By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with), antifreeze (can
Add and can be not added with), through high speed shear mix homogeneously, add bromothalonil, kasugarnycin, at ball
Ball milling 2～3 hours in grinding machine, make diameter of particle all below 5 μm, surplus deionization
Water is supplied, and can be prepared by suspending agent product of the present invention, is specifically shown in Table 3.
Table 3 embodiment 13～16 each component and weight portion
Embodiment 17～18 suspension emulsion
By dispersant, defoamer, thickening agent (can add and can be not added with), (can add can for antifreeze
It is not added with) through high speed shear mix homogeneously, add bromothalonil, ball milling 2～3 in ball mill
Hour, make diameter of particle all below 5 μm, prepare the suspending agent of bromothalonil, then will
Kasugarnycin, solvent, emulsifying agent and the various direct emulsifying of auxiliary agent high speed agitator are to suspending
In agent, surplus deionized water is supplied, and prepares suspension emulsion product of the present invention, specifically
It is shown in Table 4.
Table 4 embodiment 17～18 each component and weight portion
Embodiment 19～22 aqueous emulsion
Bromothalonil, kasugarnycin, solvent, emulsifying agent are added together, make to be dissolved into uniform oil
Phase；By deionized water, antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), disappear
Infusion mixes, and becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, remaining
Amount deionized water is supplied；Can be prepared by aqueous emulsion product of the present invention, be specifically shown in Table 5.
Table 5 embodiment 19～22 each component and weight portion
Embodiment 23～25 microemulsion
By bromothalonil, kasugarnycin, solvent, emulsifying agent, antifreeze (can add and can be not added with),
Defoamer is sufficiently mixed the most transparent oil phase, is under agitation slowly added into deionized water, shape
Become Water in Oil emulsion, more agitated heating, be allowed to rapid phase inversion and become oil-in-water type, be cooled to
Room temperature makes up to balance, and through filtering, surplus deionized water is supplied；Can be prepared by the present invention
Described microemulsion product, is specifically shown in Table 6.
Table 6 embodiment 23～25 each component and weight portion
Embodiment 26,27 microcapsule suspending agent
By bromothalonil, kasugarnycin, macromolecule cyst material, solvent mixing, make to be dissolved into all
Even oil phase, in a shear condition, joins oil phase containing emulsifying agent, pH adjusting agent, divides
In the aqueous phase solution of powder, surplus deionized water is supplied, and bi-material occurs at oil-water interfaces
Reaction, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent of the present composition and produces
Product.Specifically it is shown in Table 7.
Table 7 embodiment 26,27 each component and weight portion
Embodiment 28,29 microcapsule suspension-suspendinagent agent
By kasugarnycin, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase,
Oil phase is joined in a shear condition containing emulsifying agent, pH adjusting agent aqueous phase solution in,
Make finely disseminated microcapsule suspending agent.By dispersant, wetting agent, defoamer, thickening agent (can
Add and can be not added with) through high speed shear mix homogeneously, add bromothalonil, ball milling in ball mill
2～3 hours, make diameter of particle all below 5 μm, prepare suspending agent, then by suspending agent
Joining in the aqueous phase solution of micro-capsule suspension, deionized water supplies surplus, makes the present invention
Compositions finely disseminated microcapsule suspension-suspendinagent agent product, is specifically shown in Table 8.
Table 8 embodiment 28,29 each component and weight portion
Embodiment 30～32 water preparation
By bromothalonil, kasugarnycin, wetting agent, antifreeze, solvent, deionized water etc. together
Mixing, prepares the aqua product of the present composition, is specifically shown in Table 9.
Table 9 embodiment 30～32 each component and weight portion
Embodiment 33～36 soluble powder
By active component bromothalonil, kasugarnycin, dispersant, wetting agent, disintegrating agent, filler
Deng drying together, weigh, pulverize, stir, the conventional processing technique such as mixing, prepare this
The soluble powder product of inventive composition, is specifically shown in Table 10.
Table 10 embodiment 33～36 each component and weight portion
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First
Potentiation ratio by Toxicity Determination, after clear and definite two kinds of medicaments are compounding by a certain percentage
(SR), SR ＜ 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR ＞ 1.5 is
Potentiation, on this basis, then carries out field test.
Test method: after prerun determines each medicament effective inhibition concentration scope, medicament is by effectively
Component content sets 5 dosage respectively and processes, if clear water comparison.With reference to " pesticide indoor biological is surveyed
Determine test rule antibacterial " carry out, use mycelial growth rate method to measure medicament to crop pathogenic bacteria
Virulence.After 72h with decussation method measure colony diameter, calculate each process net growth,
Mycelial growth inhibition rate.Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) is changed
Become logarithm value (x), try to achieve virulence regression equation (y=a+bx) with method of least square, and thus
Calculate the EC of every kind of medicament50Value.Calculate two medicament different ratio according to Wadley method simultaneously
Synergy ratio (SR), SR ＜ 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action,
SR ＞ 1.5 is potentiation.Computing formula is as follows:
Wherein: a, b are respectively the ratio that bromothalonil is shared in combination with kasugarnycin；
A is bromothalonil；
B is selected from kasugarnycin.
Application Example two:
For examination disease: cucumber bacterial angular leaf spot；Test medicine is by Shaanxi thompson biology section
Skill company limited provides.
EXPERIMENTAL DESIGN: determine the former medicine of bromothalonil and kasugarnycin and the two is different through pilot study
Effective inhibition concentration scope of proportioning mixture.
Toxicity test result
Table 11 bromothalonil toxicity test analysis of results table to cucumber bacterial angular leaf spot compounding with kasugarnycin
As shown in Table 11, bromothalonil and kasugarnycin proportioning when 80 1～1 60 to Fructus Cucumidis sativi
The potentiation ratio SR of bacterial angular leaf spot is all higher than 1.5, illustrates that both are 80 1～1 60
In the range of mixture all show potentiation, when the proportioning of bromothalonil and kasugarnycin is 30
When 1～1 10, potentiation is the most prominent, and potentiation ratio is all more than 2.30；When bromine bacterium
The proportioning of nitrile and kasugarnycin is when 1 5～20 1, and potentiation is the most prominent, synergic ratio
Value, all more than 2.55, especially increases when bromothalonil and kasugarnycin weight ratio are 10:1
Effect ratio is maximum, and potentiation is the most obvious.
Bromothalonil and kasugarnycin is found through Shanxi Thompson Biological Technology Co., Ltd.'s test
Optimum ratio is 30:1,25:1,20 1,19 1,18 1,17 1,16 1,15
1,14 1,25:2,13 1,12 1,11 1,10 1,91,81,7
1,61,51,41,31,21,3:2,11,12,13,1
4,15,16,17,18,19,1 10 time potentiation the most obvious.
Find through test simultaneously: after bromothalonil is compounding with kasugarnycin to the epidemic disease in various crop,
Powdery mildew, rust, rust, downy mildew, droop, melasma, banded sclerotial blight, speckle fall
Leaf disease, gray mold, ring spot, soft rot, leaf mold, Peptic Ulcers, anthrax, bacterial wilt,
The preventing and treating of bacterial angular leaf spot or rice blast has obvious potentiation, potentiation ratio SR
It is all higher than 1.5.
Effect experiment part: test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., carried
Confession, comparison medicament 25% bromothalonil wettable powder (commercial), 4% kasugarnycin wettable powder
Agent (commercial).
Application Example three bromothalonil and kasugarnycin and compounding preventing and treating apple anthracnose drug effect examination thereof
Test.
This test arrangement, in Liquan County, Xianyang, Shanxi province city, is investigated apple anthracnose disease and is referred to before medicine
Number, in disease early period of origination dispenser, 3 days, 10 days, 20 days investigation disease indexes after dispenser
And calculate preventive effect.Result of the test is as follows:
Table 12 bromothalonil and kasugarnycin and the compounding preventing and treating apple anthracnose test of pesticide effectiveness thereof
As can be seen from Table 12, Fructus Mali pumilae charcoal can effectively be prevented and treated after bromothalonil is compounding with kasugarnycin
Cellulitis is sick, finds that bromothalonil is multiple with kasugarnycin through Shanxi Thompson Biological Technology Co., Ltd.'s test
Apple mildew, ring spot, spot defoliation or rust can also be effectively prevented and treated, preventing and treating after joining
Effect is above 96%, is better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication
Target crop is had no adverse effects.
Application Example four bromothalonil and kasugarnycin and compounding preventing and treating rice blast drug effect examination thereof
Test.
This test arrangement, at Shaanxi Province's Hanzhong City, investigates rice blast disease index before medicine,
Disease early period of origination dispenser, investigates disease indexes and calculates for after dispenser 3 days, 10 days, 20 days
Preventive effect.Result of the test is as follows:
Table 13 bromothalonil and kasugarnycin and the compounding preventing and treating rice blast test of pesticide effectiveness thereof
As can be seen from Table 13, Oryza sativa L. rice can effectively be prevented and treated after bromothalonil is compounding with kasugarnycin
Through Shanxi Thompson Biological Technology Co., Ltd.'s test, pestilence, finds that bromothalonil is multiple with kasugarnycin
Can also effectively prevent and treat rice sheath blight disease, bacterial wilt after joining, prevention effect is above 96%, excellent
In the preventive effect of single dose, and the preventive effect phase is long.To target crop without bad shadow in test scope of medication
Ring.
Application Example five bromothalonil and kasugarnycin and compounding preventing and treating cucumber bacterial angular leaf spot thereof
The test of pesticide effectiveness.
This test arrangement, in Weinan City Dali County, Shaanxi Province, investigates cucumber bacterial angular leaf spot before medicine
Disease index, in disease early period of origination dispenser, 3 days, 10 days, 20 days investigation diseases after dispenser
Evil index also calculates preventive effect.Result of the test is as follows:
Table 14 bromothalonil and kasugarnycin and the compounding preventing and treating cucumber bacterial angular leaf spot test of pesticide effectiveness thereof
As can be seen from Table 14, Fructus Cucumidis sativi can effectively be prevented and treated after bromothalonil is compounding with kasugarnycin thin
Bacterium property angular leaf spot, through Shanxi Thompson Biological Technology Co., Ltd., test finds bromothalonil and spring thunder
Powdery mildew of cucumber, downy mildew, droop or gray mold can also be effectively prevented and treated after mycin is compounding,
Prevention effect is above 96%, is better than the preventive effect of single dose, and the preventive effect phase is long.At test medication model
Enclose and interior target crop is had no adverse effects.
Application Example six bromothalonil and kasugarnycin and the examination of compounding control of plant bacterial wilt drug effect thereof
Test.
This test arrangement, in Weinan City Dali County, Shaanxi Province, is investigated bacterial wilt of tomato disease and is referred to before medicine
Number, in disease early period of origination dispenser, 3 days, 10 days, 20 days investigation disease indexes after dispenser
And calculate preventive effect.Result of the test is as follows:
Table 15 bromothalonil and kasugarnycin and the compounding control of plant bacterial wilt test of pesticide effectiveness thereof
As can be seen from Table 15, Fructus Lycopersici esculenti can effectively be prevented and treated after bromothalonil is compounding with kasugarnycin blue or green
Through Shanxi Thompson Biological Technology Co., Ltd.'s test, rot, finds that bromothalonil is multiple with kasugarnycin
Can also effectively prevent and treat tomato wilt, epidemic disease after joining, prevention effect is above 96%, is better than
The preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven bromothalonil and kasugarnycin and the compounding preventing and treating soybean rust test of pesticide effectiveness thereof.
This test arrangement, at Xian District, Shanxi Province suburban area, investigates soybean rust disease index before medicine,
In disease early period of origination dispenser, within after dispenser 3 days, 10 days, 20 days, investigate disease indexes and count
Calculate preventive effect.Result of the test is as follows:
Table 16 bromothalonil and kasugarnycin and the compounding preventing and treating soybean rust test of pesticide effectiveness thereof
As can be seen from Table 16, Semen sojae atricolor rust can effectively be prevented and treated after bromothalonil is compounding with kasugarnycin
Through Shanxi Thompson Biological Technology Co., Ltd.'s test, disease, finds that bromothalonil compounds with kasugarnycin
After can also effectively prevent and treat Semen sojae atricolor powdery mildew, prevention effect is above 96%, is better than the anti-of single dose
Effect, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, bromothalonil compounds with kasugarnycin
Afterwards to the epidemic disease in various crop, powdery mildew, rust, rust, downy mildew, droop,
Melasma, banded sclerotial blight, spot defoliation, gray mold, ring spot, soft rot, leaf mold,
The preventive effect of the Common Diseases such as Peptic Ulcers, anthrax, bacterial wilt, bacterial angular leaf spot or rice blast
All more than 96%, being better than single dose preventive effect, potentiation is obvious.
Claims (6)
1. the composition pesticide containing bromothalonil, it is characterised in that: effective active composition is
Bromothalonil and kasugarnycin, bromothalonil and kasugarnycin weight ratio are 1 60～80 1.
Composition pesticide containing bromothalonil the most according to claim 1, it is characterised in that:
Bromothalonil is 1 40～60 1 with the weight ratio of kasugarnycin.
Composition pesticide containing bromothalonil the most according to claim 2, it is characterised in that:
The weight ratio of bromothalonil and kasugarnycin is 1:10～30:1.
Composition pesticide containing bromothalonil the most according to any one of claim 1 to 3,
It is characterized in that: compositions make wettable powder, water dispersible granules, suspending agent, suspension emulsion,
Aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent, water preparation, soluble powder
Agent, soluble granula.
Composition pesticide containing bromothalonil the most according to claim 4 is used for preventing and treating farming
The purposes of disease on thing.
Purposes the most according to claim 5, it is characterised in that: described disease is epidemic disease
Disease, powdery mildew, rust, rust, downy mildew, droop, melasma, banded sclerotial blight, speckle
Point defoliation, gray mold, ring spot, soft rot, leaf mold, Peptic Ulcers, anthrax, green grass or young crops
Rot, bacterial angular leaf spot or rice blast.
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| CN104823976A (en) * | 2015-04-09 | 2015-08-12 | 江门市植保有限公司 | Pesticide composition containing bromothalonil and kasugamycin |
| CN107711858A (en) * | 2017-10-24 | 2018-02-23 | 邓杵娇 | A kind of complex composition containing gold alloy hydride and bromothalonil |
| CN108293998A (en) * | 2018-03-18 | 2018-07-20 | 刘西芳 | bactericidal composition containing bromothalonil and carvacrol |
| CN108293997A (en) * | 2018-03-18 | 2018-07-20 | 刘西芳 | bactericidal composition containing bromothalonil and eugenol |
| CN110583669B (en) * | 2019-10-28 | 2022-03-15 | 安徽江淮园艺种业股份有限公司 | Bactericidal composition for melon diseases |
| CN115380906A (en) * | 2021-05-25 | 2022-11-25 | 北京建佳农科技发展有限责任公司 | Efficient compound bactericidal pesticide for preventing and treating anthracnose root rot and preparation and use methods thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102067857A (en) * | 2011-02-23 | 2011-05-25 | 陕西美邦农药有限公司 | Fungicide combination containing polyoxin |
| CN103392740A (en) * | 2013-07-26 | 2013-11-20 | 海南正业中农高科股份有限公司 | Kasugamycin-containing sterilization composition and application thereof |
| CN103636622A (en) * | 2013-12-02 | 2014-03-19 | 海利尔药业集团股份有限公司 | Sterilizing composition containing tetramycin and bromothalonil |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102067857A (en) * | 2011-02-23 | 2011-05-25 | 陕西美邦农药有限公司 | Fungicide combination containing polyoxin |
| CN103392740A (en) * | 2013-07-26 | 2013-11-20 | 海南正业中农高科股份有限公司 | Kasugamycin-containing sterilization composition and application thereof |
| CN103636622A (en) * | 2013-12-02 | 2014-03-19 | 海利尔药业集团股份有限公司 | Sterilizing composition containing tetramycin and bromothalonil |
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