CN106259347A - A kind of bactericidal composition containing Fenamidone - Google Patents
A kind of bactericidal composition containing Fenamidone Download PDFInfo
- Publication number
- CN106259347A CN106259347A CN201610651764.6A CN201610651764A CN106259347A CN 106259347 A CN106259347 A CN 106259347A CN 201610651764 A CN201610651764 A CN 201610651764A CN 106259347 A CN106259347 A CN 106259347A
- Authority
- CN
- China
- Prior art keywords
- fenamidone
- active component
- weight ratio
- bactericidal composition
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/34—Nitriles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of bactericidal composition containing Fenamidone, bactericidal composition containing active components A Yu active component B, active components A is selected from Fenamidone, active component B is selected from any one compound following: the weight ratio of Propamocarb or its salt, cymoxanil, Bravo, captan, iprovalicarb, and active components A and active component B is 1 80～60 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious potentiation, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of potentiation.
Description
The application is divisional application, and original application is patent application " a kind of bacterium Han imidazoles of Shaanxi Meibang Pesticide Co., Ltd.
The bactericidal composition of ketone ", the Application No. 201210196078.6 of original application, original application day is 2012.6.14.
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition containing Fenamidone answering in crop pest
With.
Technical background
Fenamidone (fenamidone) molecular formula: C17H17N3OS, chemical name: (S)-1-anilino--4-methyl-2-first
Sulfenyl-4-benzylimidazoline-5-ketone, Fenamidone and Famoxate and the mechanism of action of methoxy acrylic bactericide
It is similar, suppresses line runic to exhale by stating blocks electrons transfer in former side of body level at hydrogenation olive ferment Q mono-cytochrome C radon
Inhaling, imidazoles bacterium cave (S)-enantiomer specific activity (R)-enantiomer is much higher.
Propamocarb (Propamocarb) chemical name: 3-(dimethylamino) propyl carbamic acid propyl ester, molecular formula:
C9H21N2O2Cl.The salt of Propamocarb can be propamocarb (Propamocarb hydrochloride), chemical name: third
Base-3-(dimethylamino) propyl carbamic acid hydrochlorate.Propamocarb or its salt are respectively provided with local systemic action, also can be used as leaching
Stain processes and seed protectant.
Cymoxanil (Cymoxanil) chemical name: 2-cyano group-N-[(ethylamino-) carbonyl]-2-(methoxyl group imido grpup) second
Amide, molecular formula: C7H10N4O3, there is contact and local systemic action, spore germination can be suppressed, to downy mildew of garpe, epidemic disease etc.
Effectively, mixed with protective fungicide to extend the lasting period.
Bravo (chlorothalonil) chemical name: daconil M (2,4,5,6-tetra-chloro-1,3-benzene diformazan
Nitrile), molecular formula: C8Cl4N2.Bravo can be with the albumen of the cysteine in the glyceraldehyde 3-phosphate dehydro-genase in fungal cell
Matter combines, and destroys the metabolism of cell and loss of life power.Its Main Function is prevention fungal infection, does not has Uptake and translocation to make
With, but have good cohesiveness at plant surface, it is susceptible to rain drop erosion, has the longer drug effect phase.
Captan (captan) chemical name: 3a, 4,7,7a-tetrahydrochysene-2-(trichloromethyl sulfur)-1H iso-indoles-1,3-
(2H)-diketone, molecular formula: C9H8Cl3NO2S.Captan can prevent and treat the multiple diseases on fruit tree, vegetable, crop, it is possible to as kind
Sub-inorganic agent or pouring root prevent and treat stem wilt, damping-off, melasma.Some kind of Fructus Mali pumilae and pears there is poisoning, to Caulis et Folium Lactucae sativae, celery
Dish, Fructus Lycopersici esculenti seed have an impact.
Iprovalicarb (Iprovalicarb) chemical name: [2-methyl isophthalic acid-[1-(4-aminomethyl phenyl)-ethylcarbamoyl
Base]-propyl group]-carbamyl isopropyl ester, molecular formula: C18H28N2O3.Iprovalicarb is amino-acid ester analog derivative, has uniqueness
Brand-new biomimetic features makes its mechanism of action be different from other antibacterial preventing and treating Oomycete.Its mechanism of action is thin for acting on fungus
Cell wall and the synthesis of protein, can suppress infecting and sprouting of spore, can suppress mycelial growth simultaneously, cause it to deform,
Dead.For the fungus-caused disease of Peronosporaceae and Phytophthora, there is well treatment and eradicant action.
In the real process of agricultural production, controlling disease is easiest to generate the problem that the generation of disease drug resistance.No
Compound with kind composition, be to prevent and treat the method that resistance disease is the most common.Heterogeneity compounds, according to reality application effect
Really, judge certain compounding be potentiation, add and or antagonism.In most cases, the compounding effect of pesticide all adds
And effect, really have potentiation compounding seldom, especially potentiation clearly, potentiation ratio the highest compounding the most more
Few.Study through inventor, find Fenamidone and Propamocarb or its salt, cymoxanil, Bravo, captan, iprovalicarb
Mutually compounding, have good potentiation within the specific limits, and about Fenamidone and Propamocarb or its salt, cymoxanil, hundred
Bacterium is clear, the relevant of captan, iprovalicarb compounds, and the most at home and abroad there is not yet relevant report.
Summary of the invention
The purpose of the present invention is to propose to a kind of have that synergistic function, use cost be low, preventive effect is good containing Fenamidone
Bactericidal composition.
The present invention is to be achieved through the following technical solutions:
A kind of bactericidal composition containing Fenamidone, containing active components A and active component B, active components A becomes with activity
Point B weight ratio is 1 80～60 1, and described active components A is selected from Fenamidone, active component B selected from Propamocarb or its salt,
One of cymoxanil, Bravo, captan, iprovalicarb are planted, the preferred weight ratio of active components A and active component B be 1 60～
40 1；More preferably Fenamidone is 1 35～5 1 with the weight ratio of Propamocarb or its salt, Fenamidone and the weight of cymoxanil
Ratio is 1 30～20 1, and Fenamidone is 1 40～1 1 with the weight ratio of Bravo, and Fenamidone with the weight ratio of captan is
1 40～5 1, Fenamidone is 1 30～20 1 with the weight ratio of iprovalicarb；Most preferably Fenamidone and Propamocarb or its salt
Weight ratio be 1 20～1 1, the weight ratio of Fenamidone and cymoxanil is 1 10～10 1, the weight of Fenamidone and Bravo
Amount ratio is 1 20～1 1, and Fenamidone is 1 20～1 1 with the weight ratio of captan, Fenamidone and the weight ratio of iprovalicarb
It is 1 10～10 1.
The described bactericidal composition containing Fenamidone is for preventing and treating the application of the disease of crop, and described crop includes grain
Food crop, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, root
Stem class crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop.
The described bactericidal composition containing Fenamidone is for preventing and treating the application of the disease of crop, and described disease includes frost
Mildew, late blight, early blight, melasma, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, grey mold
Disease, leaf mold, anthrax, scab, ring spot, resin disease, phytophthora root rot, damping-off.
In the present composition, the content of active component depends on amount of application when being used alone, and also depends on a kind of chemical combination
The mixed ratio of thing and another kind of compound and potentiation degree, also the most relevant with target disease.Generally in compositions
The weight percentage of active component is the 1%～90% of gross weight, is preferably 5%～80%.According to different preparation classes
Type, active component content scope is different.Generally, liquid preparation contains the active substance of by weight 1%～60%, preferably
Ground is 5%～50%；Solid preparation contains the active substance of by weight 5%～80%, preferably 10%～80%.
At least containing a kind of surfactant in the bactericidal composition of the present invention, when being beneficial to use, active component is in water
Dispersion.Surface-active contents is the 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by the bactericidal composition of the present invention is known in those skilled in the art: can be selected from
One or more in dispersant, wetting agent, thickening agent or defoamer.According to different dosage form, preparation can also contain this area
Stabilizer well known to technical staff, antifreeze etc..
The bactericidal composition of the present invention through dilution or directly can be used before use by user.Its preparation can be by ability
Prepared by the processing method well known to field technique personnel, will add after active component mixes with liquid flux or solid carrier
One or more in surfactant such as dispersant, stabilizer, wetting agent, binding agent, defoamer etc..
The bactericidal composition of the present invention, can be processed into acceptable dosage form on any pesticide on demand.Wherein preferably agent
Type is wettable powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-outstanding
Floating agent, it is possible to make water preparation, soluble liquid, soluble powder.
Compositions comprises following component and content when making wettable powder: active components A 1%～60%, active component
B 1%～80%, dispersant 1%～12%, wetting agent 1%～8%, filler surplus.
Compositions includes following component and content when making water dispersible granules: active components A 1%～60%, active component
B 1%～80%, dispersant 1%～12%, wetting agent 1%～8%, disintegrating agent 1%～10%, binding agent 0～8%, filler
Surplus.
Compositions includes following component and content when making suspending agent: active components A 1%～50%, active component B
1%～50%, dispersant 1%～10%, wetting agent 1%～10%, defoamer 0.01%～2%, thickening agent 0～2%, freeze proof
Agent 0～8%, deionized water add to 100%.
Compositions includes following component and content when making suspension emulsion: active components A 1%～50%, active component B
1%～50%, emulsifying agent 1%～10%, dispersant 1%～10%, solvent 0～20%, defoamer 0.01%～2%, thickening
Agent 0～2%, antifreeze 0～8%, deionized water add to 100%.
Compositions includes following component and content when making microemulsion: active components A 1%～50%, active component B1%
～50%, emulsifying agent 3%～25%, solvent 1%～10%, antifreeze 0～8%, defoamer 0.01%～2%, deionized water
Add to 100%.
Compositions includes following component and content when making aqueous emulsion: active components A 1%～50%, active component B
1%～50%, solvent 1%～20%, emulsifying agent 1%～12%, antifreeze 0～8%, defoamer 0.01%～2%, thickening agent
0～2%, deionized water add to 100%.
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1) present composition has good potentiation and lasting effect within the specific limits, and preventive effect is higher than single dose；(2) agriculture
Medicinal dose reduces, and reduces pesticide residual quantity on crop, alleviates environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases
As downy mildew, late blight, early blight, melasma, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot,
Gray mold, leaf mold, anthrax, scab, ring spot, resin disease, phytophthora root rot, damping-off have greater activity.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but
The invention is not limited in this.
Application Example one
Embodiment 1～18 wettable powder
By Fenamidone, active component B, dispersant, wetting agent, filler mixing, mix homogeneously in mixed cylinder, through air-flow
Pulverizer remixes uniformly after pulverizing, and i.e. can be made into wettable powder product of the present invention.Specifically it is shown in Table 1.
Table 1 embodiment 1～18 each component and content
Embodiment 19～33 water dispersible granules
By Fenamidone, active component B, dispersant, wetting agent, disintegrating agent, binding agent (can add and can be not added with), filler together
Obtain the particle diameter needed through comminution by gas stream, obtain granulation materials.System is passed through in item is quantitatively sent into fluidized bed granulating dryer
Grain and dried, prepares water dispersible granules product of the present invention.Specifically it is shown in Table 2.
Table 2 embodiment 19～33 each component and content
Embodiment 34～50 suspending agent
By dispersant, wetting agent, thickening agent (can add and can be not added with), defoamer, antifreeze (can add and can be not added with) through at a high speed
Shear-mixed is uniform, adds Fenamidone, active component B, supplies surplus with deionized water, and in ball mill, ball milling 2～3 is little
Time, make diameter of particle all below 5 μm, prepare suspending agent product of the present invention.Specifically it is shown in Table 3.
Table 3 embodiment 34～50 each component and content
By Propamocarb in table 1 to table 3 or its salt, cymoxanil, Bravo, captan, iprovalicarb exchange, brand-new can be prepared
Agent.
Embodiment 51～56 suspension emulsion
By dispersant, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with), deionized water through too high
Speed shear-mixed is uniform, adds Fenamidone, ball milling 2～3 hours in ball mill, makes diameter of particle all below 5 μm, system
Obtain Fenamidone suspending agent, then by active component B, solvent (can add and can be not added with), emulsifying agent and various auxiliary agent high-speed stirred
The direct emulsifying of device, in suspending agent, prepares suspension emulsion product of the present invention.Specifically it is shown in Table 4.
Table 4 embodiment 51～56 each component and content
Cymoxanil, Bravo, captan, iprovalicarb in table 4 are exchanged, novel formulation can be prepared.
Embodiment 57～68 aqueous emulsion
Fenamidone, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；By deionized water,
Antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), defoamer mix, and become homogeneous aqueous phase.In high-speed stirred
Under, aqueous phase is added oil phase, prepares aqueous emulsion product of the present invention.Specifically it is shown in Table 5.
Table 5 example 57～68 each component and content
By Propamocarb in table 5 or its salt, cymoxanil, Bravo, captan, iprovalicarb exchange, novel formulation can be prepared.
Embodiment 69～71 microemulsion
Being dissolved in Fenamidone, active component B equipped with in the homogenizer of solvent, by emulsifying agent, antifreeze, (can add can not
Add), defoamer join in the homogenizer equipped with above-mentioned solution, strongly mix and even after supplying surplus with deionized water
Change, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically it is shown in Table 6.
Table 6 embodiment 69～71 each component and content
Embodiment 72,73 microcapsule suspending agent
By Fenamidone, active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, shearing
Under the conditions of, oil phase is joined containing emulsifying agent, pH adjusting agent, dispersant, defoamer aqueous phase solution in, mend with deionized water
Foot surplus, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the present composition finely disseminated micro-
Capsule suspending agent product.Specifically it is shown in Table 7.
Table 7 embodiment 72,73 each component and content
Embodiment 74,75 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, by oil phase at shearing condition
Under join containing emulsifying agent, pH adjusting agent aqueous phase solution in, make finely disseminated microcapsule suspending agent.By dispersant, wet
Profit agent, defoamer, thickening agent (can add and can be not added with), through high speed shear mix homogeneously, add Fenamidone, ball in ball mill
Grind 2～3 hours, make diameter of particle all below 5 μm, prepare suspending agent, then suspending agent is joined micro-capsule suspension
Aqueous phase solution in, deionized water supplies surplus, makes the present composition finely disseminated microcapsule suspension-suspendinagent agent product.
Specifically it is shown in Table 8.
Table 8 embodiment 74,75 each component and content
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through indoor virulence to survey
Fixed, after clear and definite two kinds of medicaments are compounding by a certain percentage potentiation ratio (SR), SR ＜ 0.5 is antagonism, 0.5≤SR≤1.5
For summation action, SR ＞ 1.5 is potentiation, on this basis, then carries out field test.
Test method: after prerun determines each medicament effective inhibition concentration scope, medicament is set 5 respectively by active constituent content
Individual dosage processes, if clear water comparison.Carry out with reference to " farm-chemical indoor determination test rule antibacterial ", use mycelial growth speed
Rate method measures the medicament virulence to crop pathogenic bacteria.Measure colony diameter by decussation method after 72h, calculate each process and only grow
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) is converted into logarithm value (x), with minimum
Square law tries to achieve virulence regression equation (y=a+bx), and thus calculates the EC of every kind of medicament50Value.Simultaneously according to Wadley method
Calculating two medicaments different ratio synergy ratio (SR), SR ＜ 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action,
SR ＞ 1.5 is potentiation.Computing formula is as follows:
Wherein: a, b are respectively the ratio that active components A is shared in combination with active component B；A is Fenamidone；B selects
Plant to Propamocarb or one of its salt, cymoxanil, Bravo, captan, iprovalicarb.
Application Example two:
For examination disease: tomato blight；Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd.；EXPERIMENTAL DESIGN: pass through
Pilot study determines Fenamidone and Propamocarb or the former medicine of its salt and effective inhibition concentration scope of the two different ratio mixture.
Toxicity test result
Table 9 Fenamidone toxicity test analysis of results table to tomato blight compounding with Propamocarb or its salt
As shown in Table 9, Fenamidone and Propamocarb or its salt compound the proportioning of preventing and treating tomato blight when 1 80～60 1,
Potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixture in the range of 1 80～60 1, works as Fenamidone
With the proportioning of Propamocarb or its salt when 1 35～5 1, potentiation is the most prominent, and potentiation ratio is all higher than 2.20.Through test
The optimum ratio finding Fenamidone and Propamocarb or its salt is 5:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:
9,1:10,1:11,1:12,1:13,1:14,1:15,1:20,1:25,1:30,1:35, especially when Fenamidone and Propamocarb
Or its salt weight ratio when being 1:7 potentiation ratio maximum, potentiation is the most obvious.
Application Example three:
For examination disease: downy mildew of crucifers；Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd.；Test
Design: determine Fenamidone and the former medicine of cymoxanil and effective inhibition concentration model of the two different ratio mixture through pilot study
Enclose.
Toxicity test result
Table 10 Fenamidone toxicity test analysis of results table to downy mildew of crucifers compounding with cymoxanil
As shown in Table 10, Fenamidone and cymoxanil compound the proportioning preventing and treating downy mildew of crucifers 1 80～
When 60 1, potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixture in the range of 1 80～60 1, when
The proportioning of Fenamidone and cymoxanil is when 1 30～20 1, and potentiation is the most prominent, and potentiation ratio is all higher than 2.25.Through examination
The optimum ratio issuing after examination and approval existing Fenamidone and cymoxanil is 20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,
2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially work as imidazoles
When bacterium ketone and cymoxanil weight ratio are 2:3, potentiation ratio is maximum, and potentiation is the most obvious.
Application Example four:
For examination disease: downy mildew of garpe；Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd.；EXPERIMENTAL DESIGN: warp
Cross pilot study and determine Fenamidone and the former medicine of Bravo and effective inhibition concentration scope of the two different ratio mixture.
Toxicity test result
Table 11 Fenamidone and the chlorothalonil compound toxicity test analysis of results table to downy mildew of garpe
As shown in Table 11, Fenamidone and chlorothalonil compound prevent and treat the proportioning of downy mildew of garpe when 1 80～60 1, increase
Effect ratio SR is all higher than 1.5, illustrate that both all show potentiation at mixture in the range of 1 80～60 1, when Fenamidone and
The proportioning of Bravo is when 1 40～1 1, and potentiation is the most prominent, and potentiation ratio is all higher than 2.25.Imidazoles is found through test
The optimum ratio of bacterium ketone and Bravo is 1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:
25,1:30,1:35,1:40, especially when Fenamidone and Bravo weight ratio are 1:10, potentiation ratio is maximum, potentiation
The most obvious.
Application Example five:
For examination disease: the late blight of potato；Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd.；EXPERIMENTAL DESIGN:
Fenamidone and the former medicine of captan and effective inhibition concentration scope of the two different ratio mixture is determined through pilot study.
Toxicity test result
Table 12 Fenamidone toxicity test analysis of results table to the late blight of potato compounding with captan
As shown in Table 12, Fenamidone and captan compound the proportioning preventing and treating the late blight of potato when 1 80～60 1,
Potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixture in the range of 1 80～60 1, works as Fenamidone
With the proportioning of captan when 1 40～5 1, potentiation is the most prominent, and potentiation ratio is all higher than 2.15.Miaow is found through test
The optimum ratio of cycloheximide triazole and captan is 5:1,4:1,3:1,2:1,1:1,1:2,2:5,1:3,1:4,1:5,1:6,1:7,1:
8,1:9,1:10,1:15,1:20,1:25,1:30,1:35,1:40, is especially 1:8 when Fenamidone and captan weight ratio
Shi Zengxiao ratio is maximum, and potentiation is the most obvious.
Application Example six:
For examination disease: cucumber downy mildew；Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd.；EXPERIMENTAL DESIGN: warp
Cross pilot study and determine Fenamidone and the former medicine of iprovalicarb and effective inhibition concentration scope of the two different ratio mixture.
Toxicity test result
Table 13 Fenamidone toxicity test analysis of results table to cucumber downy mildew compounding with iprovalicarb
As shown in Table 13, Fenamidone and iprovalicarb compound the proportioning of preventing and treating cucumber downy mildew when 1 80～60 1, increase
Effect ratio SR is all higher than 1.5, illustrate that both all show potentiation at mixture in the range of 1 80～60 1, when Fenamidone and
The proportioning of iprovalicarb is when 1 30～20 1, and potentiation is the most prominent, and potentiation ratio is all higher than 2.20.Especially when imidazoles bacterium
When ketone and iprovalicarb weight ratio are 2:3, potentiation ratio is maximum, and potentiation is the most obvious.
Find through test: to downy mildew, late blight, early blight, melasma, speckle after Fenamidone is compounding with active component B
Maize ear rot, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthrax, scab, wheel stricture of vagina
Disease, resin disease, phytophthora root rot, the preventing and treating of damping-off have obvious potentiation, and potentiation ratio is all more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided.Comparison medicament: 20% Fenamidone suspending agent
(autogamy), 35% Propamocarb water preparation (commercial), 25% cymoxanil wettable powder (autogamy), 75% Bravo wettable powder
(commercial), 50% captan wettable powder (commercial), 20% iprovalicarb wettable powder (autogamy).
Application Example seven Fenamidone and active component B and the compounding preventing and treating tomato late blight test of pesticide effectiveness thereof
This test arrangement, at Xian District, Shanxi Province suburban area, investigates the tomato late blight state of an illness before medicine, in first time at state of an illness initial stage
Dispenser, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate anti-
Effect.Experimental result is as follows:
Table 14 Fenamidone and active component B and the compounding preventing and treating tomato late blight test of pesticide effectiveness thereof
As can be seen from Table 14, tomato late blight, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight Fenamidone and active component B and the compounding preventing and treating cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement, in Jingyang County, Shaanxi Province, investigates the cucumber downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage,
Dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Real
Test result as follows:
Table 15 Fenamidone and active component B and the compounding preventing and treating cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 15, cucumber downy mildew, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine Fenamidone and active component B and compounding prevent and treat the downy mildew of garpe test of pesticide effectiveness
This test arrangement, in Weinan City suburb, Shaanxi Province, investigates the downy mildew of garpe state of an illness before medicine, in first time at state of an illness initial stage
Dispenser, dispenser in every 7 days once, is total to dispenser 3 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate anti-
Effect.Experimental result is as follows:
Table 16 Fenamidone and active component B and compounding prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 16, downy mildew of garpe, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten Fenamidone and active component B and the compounding preventing and treating alternaria leaf spot of apple test of pesticide effectiveness thereof
This test arrangement, in Weinan City Pucheng County, Shaanxi Province, investigates the alternaria leaf spot of apple state of an illness, in the state of an illness initial stage before medicine
Dispenser for the first time, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index also respectively
Calculate preventive effect.Experimental result is as follows:
Table 17 Fenamidone and active component B and the compounding preventing and treating alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 17, alternaria leaf spot of apple can effectively be prevented and treated after Fenamidone is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long, and can treat apple anthracnose, ring spot, prevention effect after 14 days
Up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example 11 Fenamidone and active component B and the compounding preventing and treating wheat powdery mildew test of pesticide effectiveness thereof
This test arrangement, at Shaanxi Province's Weinan City, investigates the wheat powdery mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage,
Dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Real
Test result as follows:
Table 18 Fenamidone and active component B and the compounding preventing and treating wheat powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 18, wheat powdery mildew, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten diimidazole bacterium ketone and active component B and compounding prevent and treat downy mildew of crucifers drug effect
Test
This test arrangement, at Xian District, Shanxi Province suburban area, investigates the downy mildew of crucifers state of an illness, at the beginning of the state of an illness before medicine
Phase dispenser for the first time, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively
And calculate preventive effect.Experimental result is as follows:
Table 19 Fenamidone and active component B and compounding prevent and treat the downy mildew of crucifers test of pesticide effectiveness
As can be seen from Table 19, after Fenamidone is compounding with active component B, can effectively prevent and treat downy mildew of crucifers,
Prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 13 Fenamidone and active component B and the compounding preventing and treating peronophythora litchi test of pesticide effectiveness thereof
This test arrangement, in Huilai county, Guangdong Province, is investigated the peronophythora litchi state of an illness, is executed for the first time in the state of an illness initial stage before medicine
Medicine, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.
Experimental result is as follows:
Table 20 Fenamidone and active component B and the compounding preventing and treating peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 20, peronophythora litchi, preventing and treating effect can effectively be prevented and treated after Fenamidone is compounding with active component B
Fruit is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten tetramisole bacterium ketone and active component B and the compounding preventing and treating Fructus Cucumidis sativi damping off test of pesticide effectiveness thereof
This test arrangement, in Jingyang County, Shaanxi Province, investigates the Fructus Cucumidis sativi damping off state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage,
Dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Real
Test result as follows:
Table 21 Fenamidone and active component B and the compounding preventing and treating Fructus Cucumidis sativi damping off test of pesticide effectiveness thereof
As can be seen from Table 21, Fructus Cucumidis sativi damping off, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 15 Fenamidone and active component B and the compounding preventing and treating Cabbage Leaf Spot test of pesticide effectiveness thereof
This test arrangement, in Qishan County of Baoji, Shaanxi province city, investigates the Cabbage Leaf Spot state of an illness, in the state of an illness initial stage first before medicine
Secondary dispenser, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate
Preventive effect.Experimental result is as follows:
Table 22 Fenamidone and active component B and the compounding preventing and treating Cabbage Leaf Spot test of pesticide effectiveness thereof
As can be seen from Table 22, Cabbage Leaf Spot, prevention effect can effectively be prevented and treated after Fenamidone is compounding with active component B
It is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, Fenamidone and Propamocarb or its salt, cymoxanil, hundred bacterium
Clearly, to the downy mildew in various crop, late blight, early blight, melasma, mottled rot disease after captan, iprovalicarb compound, damping off
Disease, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthrax, scab, ring spot, resin disease,
The preventive effect of the Common Diseases such as phytophthora root rot, damping-off, all more than 95%, is better than single dose preventive effect, and potentiation is obvious.
Claims (6)
1. the bactericidal composition containing Fenamidone, it is characterised in that: containing active components A and active component B, active component
A and active component B weight ratio are 1 80～60 1, and described active components A is selected from Fenamidone, and active component B is selected from frost urea
One of cyanogen, Bravo, captan, iprovalicarb are planted.
Bactericidal composition containing Fenamidone the most according to claim 1, it is characterised in that: active components A becomes with activity
The weight ratio dividing B is 1 60～40 1.
Bactericidal composition containing Fenamidone the most according to claim 2, it is characterised in that:
Fenamidone is 1 30～20 1 with the weight ratio of cymoxanil；
Fenamidone is 1 40～1 1 with the weight ratio of Bravo；
Fenamidone is 1 40～5 1 with the weight ratio of captan；
Fenamidone is 1 30～20 1 with the weight ratio of iprovalicarb.
4. according to the bactericidal composition containing Fenamidone described in any one in claim 1-3, it is characterised in that: compositions
Make wettable powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-outstanding
Floating agent.
Bactericidal composition containing Fenamidone the most according to claim 4 is for preventing and treating the application of crop pest.
Application the most according to claim 5, it is characterised in that: described disease include downy mildew, late blight, early blight,
Melasma, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthrax, black
Star disease, ring spot, resin disease, phytophthora root rot, damping-off.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610651764.6A CN106259347A (en) | 2012-06-14 | 2012-06-14 | A kind of bactericidal composition containing Fenamidone |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610651764.6A CN106259347A (en) | 2012-06-14 | 2012-06-14 | A kind of bactericidal composition containing Fenamidone |
| CN201210196078.6A CN103478152B (en) | 2012-06-14 | 2012-06-14 | Fenamidone-containing sterilization composition |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210196078.6A Division CN103478152B (en) | 2012-06-14 | 2012-06-14 | Fenamidone-containing sterilization composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106259347A true CN106259347A (en) | 2017-01-04 |
Family
ID=49819017
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610651764.6A Pending CN106259347A (en) | 2012-06-14 | 2012-06-14 | A kind of bactericidal composition containing Fenamidone |
| CN201210196078.6A Active CN103478152B (en) | 2012-06-14 | 2012-06-14 | Fenamidone-containing sterilization composition |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210196078.6A Active CN103478152B (en) | 2012-06-14 | 2012-06-14 | Fenamidone-containing sterilization composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN106259347A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105265439A (en) * | 2014-07-02 | 2016-01-27 | 江苏龙灯化学有限公司 | Method for controlling plant pythium |
| CN108739838A (en) * | 2018-07-19 | 2018-11-06 | 广东广康生化科技股份有限公司 | A kind of efficient bactericidal composite containing folpet and Fenamidone |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153454A (en) * | 1994-07-22 | 1997-07-02 | 罗纳-普朗克农业化学公司 | Fungicidal composition including 2-imidazoline-5-one |
| EP1023832A1 (en) * | 1999-01-29 | 2000-08-02 | American Cyanamid Company | Aqueous suspension concentrate |
| CN1338897A (en) * | 1999-02-02 | 2002-03-06 | 拜尔公司 | Fungicidal active substance combinations |
| CN1515153A (en) * | 1997-12-02 | 2004-07-28 | 罗纳-普朗克农业化学公司 | Fungicide composition containing 2-imidazoline-5-ketone |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100340167C (en) * | 2002-12-06 | 2007-10-03 | 陶氏农业科学公司 | Synergistic compositions |
| CL2007003743A1 (en) * | 2006-12-22 | 2008-07-11 | Bayer Cropscience Ag | COMPOSITION THAT INCLUDES FENAMIDONA AND AN INSECTICIDE COMPOUND; AND METHOD TO CONTROL FITOPATOGENOS CULTURES AND INSECTS FACING OR PREVENTIVELY. |
| BRPI0917760A2 (en) * | 2008-12-16 | 2015-08-11 | Basf Se | Mixture, agrochemical composition, method for controlling phytopathogenic harmful fungi, seed and process for preparing a composition |
-
2012
- 2012-06-14 CN CN201610651764.6A patent/CN106259347A/en active Pending
- 2012-06-14 CN CN201210196078.6A patent/CN103478152B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153454A (en) * | 1994-07-22 | 1997-07-02 | 罗纳-普朗克农业化学公司 | Fungicidal composition including 2-imidazoline-5-one |
| CN1515153A (en) * | 1997-12-02 | 2004-07-28 | 罗纳-普朗克农业化学公司 | Fungicide composition containing 2-imidazoline-5-ketone |
| EP1023832A1 (en) * | 1999-01-29 | 2000-08-02 | American Cyanamid Company | Aqueous suspension concentrate |
| CN1338897A (en) * | 1999-02-02 | 2002-03-06 | 拜尔公司 | Fungicidal active substance combinations |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103478152A (en) | 2014-01-01 |
| CN103478152B (en) | 2017-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103651538B (en) | A kind of bactericidal composition containing zoxamide | |
| CN102239855A (en) | Bactericidal composition containing trifloxystrobin and triazole | |
| CN103518724B (en) | Bactericidal composition containing fluopyram and methoxyacrylate | |
| CN105851058A (en) | Sterilization composition containing captan and copper preparation | |
| CN103875684A (en) | High efficient sterilizing composition containing initium | |
| CN103355352B (en) | Bactericidal composition containing antibiotic in pyrimidine nucleoside class Yu methoxy acrylic | |
| CN106259347A (en) | A kind of bactericidal composition containing Fenamidone | |
| CN104642341A (en) | Bactericidal composition containing zinc thiazole | |
| CN103563971A (en) | Bactericidal composition containing simeconazole and methoxy acrylate | |
| CN104285954A (en) | Efficient fungicidal composition | |
| CN106234367A (en) | A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic | |
| CN104222118A (en) | Bactericidal composition | |
| CN103621550B (en) | Chesulfamide-containing pesticide composition | |
| CN101642109A (en) | Bactericidal composition containing famoxadone | |
| CN103621562B (en) | A kind of bactericidal composition | |
| CN103651450B (en) | Bactericidal composition containing dimoxystrobin and thiocarbamate | |
| CN103444744A (en) | Sterilization composition containing fenamidone and strobilurin | |
| CN103583560B (en) | A kind of bactericidal composition containing simeconazoles and thiocarbamates | |
| CN103416416B (en) | A kind of bactericidal composition containing tiadinil | |
| CN103583536A (en) | Pesticide composition | |
| CN103503894B (en) | A kind of bactericidal composition containing Fenamidone | |
| CN103444754B (en) | A kind of bactericidal composition of Quinoxyfen-containinsterilization | |
| CN103416417B (en) | The fungicidal composition of a kind of fluorine-containing azoles bacterium acid amides | |
| CN103444722B (en) | A kind of Quinoxyfen-containinsterilization and the bactericidal composition of triazole type | |
| CN103416415B (en) | A kind of bactericidal composition containing tiadinil Yu methoxy acrylic |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170104 |
|
| WD01 | Invention patent application deemed withdrawn after publication |