CN104470517B - 注射用抗生素制剂及其使用方法 - Google Patents

注射用抗生素制剂及其使用方法 Download PDF

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Publication number
CN104470517B
CN104470517B CN201380038000.4A CN201380038000A CN104470517B CN 104470517 B CN104470517 B CN 104470517B CN 201380038000 A CN201380038000 A CN 201380038000A CN 104470517 B CN104470517 B CN 104470517B
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China
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composition
pnt
agent
ot11pntrtu
preparation
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CN201380038000.4A
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English (en)
Chinese (zh)
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CN104470517A (zh
Inventor
F·A·阿拉维
O·博克
R·贾殷
K·南加
I·G·图克
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Ylanco New Zealand
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Bayer New Zealand Ltd
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Priority claimed from NZ613138A external-priority patent/NZ613138B2/en
Application filed by Bayer New Zealand Ltd filed Critical Bayer New Zealand Ltd
Publication of CN104470517A publication Critical patent/CN104470517A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201380038000.4A 2012-07-17 2013-07-16 注射用抗生素制剂及其使用方法 Active CN104470517B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
NZ60129912 2012-07-17
NZ601299 2012-07-17
NZ61017513 2013-05-03
NZ610175 2013-05-03
NZ613138A NZ613138B2 (en) 2013-07-12 Injectable antibiotic formulations and their methods of use
NZ613138 2013-07-12
PCT/NZ2013/000123 WO2014014363A1 (en) 2012-07-17 2013-07-16 Injectable antibiotic formulations and their methods of use

Publications (2)

Publication Number Publication Date
CN104470517A CN104470517A (zh) 2015-03-25
CN104470517B true CN104470517B (zh) 2018-12-18

Family

ID=49949085

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380038000.4A Active CN104470517B (zh) 2012-07-17 2013-07-16 注射用抗生素制剂及其使用方法

Country Status (30)

Country Link
US (1) US10376585B2 (cg-RX-API-DMAC10.html)
EP (1) EP2874624B8 (cg-RX-API-DMAC10.html)
JP (1) JP6189437B2 (cg-RX-API-DMAC10.html)
KR (1) KR102113822B1 (cg-RX-API-DMAC10.html)
CN (1) CN104470517B (cg-RX-API-DMAC10.html)
AU (1) AU2013290826B2 (cg-RX-API-DMAC10.html)
BR (1) BR112014031083B1 (cg-RX-API-DMAC10.html)
CA (1) CA2875351C (cg-RX-API-DMAC10.html)
CL (1) CL2014003423A1 (cg-RX-API-DMAC10.html)
CO (1) CO7240359A2 (cg-RX-API-DMAC10.html)
CR (1) CR20140550A (cg-RX-API-DMAC10.html)
DK (1) DK2874624T3 (cg-RX-API-DMAC10.html)
DO (1) DOP2014000288A (cg-RX-API-DMAC10.html)
ES (1) ES2752034T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20191730T1 (cg-RX-API-DMAC10.html)
HU (1) HUE046427T2 (cg-RX-API-DMAC10.html)
IL (1) IL236713B (cg-RX-API-DMAC10.html)
LT (1) LT2874624T (cg-RX-API-DMAC10.html)
MX (2) MX387668B (cg-RX-API-DMAC10.html)
MY (1) MY172561A (cg-RX-API-DMAC10.html)
NI (1) NI201400152A (cg-RX-API-DMAC10.html)
PH (1) PH12014502716B1 (cg-RX-API-DMAC10.html)
PL (1) PL2874624T3 (cg-RX-API-DMAC10.html)
PT (1) PT2874624T (cg-RX-API-DMAC10.html)
RU (1) RU2643327C2 (cg-RX-API-DMAC10.html)
SI (1) SI2874624T1 (cg-RX-API-DMAC10.html)
SV (1) SV2014004882A (cg-RX-API-DMAC10.html)
UA (1) UA118654C2 (cg-RX-API-DMAC10.html)
WO (1) WO2014014363A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201409322B (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2729328T3 (es) * 2012-12-20 2019-10-31 Alleva Animal Health Ltd Formulaciones inyectables veterinarias de penetamato

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2087236A (en) * 1980-11-17 1982-05-26 Leo Pharm Prod Ltd Pharmaceutical preparations containing a 6 beta -halopenicillanic acid
US4594246A (en) * 1979-05-21 1986-06-10 Leo Pharmaceutical Products Pharmaceutically-acceptable amine salts of 6-β-halopenicillanic acids
CN1517090A (zh) * 2003-01-20 2004-08-04 王玉万 含抗菌药物的兽用混悬注射剂或乳剂
WO2010102196A2 (en) * 2009-03-05 2010-09-10 Insite Vision Incorporated Controlled-release ophthalmic vehicles

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51516B1 (en) * 1980-10-06 1987-01-07 Leo Pharm Prod Ltd 1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate
IL64009A (en) 1980-10-31 1984-09-30 Rech Applications Therap Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate tosylate hydrates,their production and pharmaceutical compositions containing them
EP0115001B1 (de) 1982-12-28 1988-06-15 Bayer Ag Stabile Aminoglykosid-Penicillin-Injektionsformulierungen
US5736151A (en) 1996-12-09 1998-04-07 Pharmacia & Upjohn Company Antibiotic oil suspensions
CH693625A5 (it) * 1999-02-18 2003-11-28 Inpharma Sa Composizioni farmaceutiche contenenti composti ad attività promotrice di assorbimento di principi attivi.
US20040022815A1 (en) 2002-08-05 2004-02-05 Orchid Health Care Novel pharmaceutical composition of ceftiofur
KR20040015622A (ko) 2002-08-13 2004-02-19 대한뉴팜(주) 세프티오푸르나트륨을 활성성분으로 함유하는 현탁주사액조성물
US6911441B2 (en) 2002-12-16 2005-06-28 Akzo Nobel N.V. Prolonged release pharmaceutical composition
US20050143347A1 (en) * 2003-12-22 2005-06-30 Aventis Pharma Deutschland Gmbh Medicinal lipolysis of accumulations of fat
DE102004025324A1 (de) * 2004-05-19 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung
US20060142234A1 (en) 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
US8679540B2 (en) * 2006-06-09 2014-03-25 Flamel Technologies Pharmaceutical formulations for the prolonged release of active principle(s), and their applications, especially therapeutic applications
PL2214656T3 (pl) * 2007-10-26 2019-06-28 Avivagen Inc. Kompozycje i sposoby wzmacniania odpowiedzi immunologicznej
HRP20140939T1 (hr) * 2008-05-07 2014-11-21 Salix Pharmaceuticals, Ltd. Davanje preparata za äśišä†enje crijeva i antibiotika za lijeäśenje bolesti crijeva
WO2010138918A1 (en) * 2009-05-29 2010-12-02 Pacira Pharmaceuticals, Inc. Hyaluronidase as an adjuvant for increasing the injection volume and dispersion of large diameter synthetic membrane vesicles containing a therapeutic agent
CN101822637A (zh) 2009-12-31 2010-09-08 天津瑞普生物技术股份有限公司 一种含有β-内酰胺类抗生素的混悬注射剂
US20110223208A1 (en) * 2010-03-09 2011-09-15 Beth Hill Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations
DE102010015143A1 (de) 2010-04-16 2011-10-20 Cts Chemical Industries Ltd. Stabile flüssige ölige gebrauchsfertige Formulierungen, Herstellung davon und Verwendung davon
EP2723335A4 (en) * 2011-06-23 2015-01-07 Bayer New Zealand Ltd ANTIPARASITIC COMPOSITION WITH A MACROCYCLIC LACTON AND LEVAMISOL AND METHOD FOR THE TREATMENT OF PARASITIC ATTACK
AU2012359296B2 (en) 2011-12-23 2014-12-11 Elanco New Zealand Antibiotic formulations
WO2013129944A1 (en) * 2012-02-27 2013-09-06 Bayer New Zealand Limited Controlled release compositions and their methods of use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594246A (en) * 1979-05-21 1986-06-10 Leo Pharmaceutical Products Pharmaceutically-acceptable amine salts of 6-β-halopenicillanic acids
GB2087236A (en) * 1980-11-17 1982-05-26 Leo Pharm Prod Ltd Pharmaceutical preparations containing a 6 beta -halopenicillanic acid
CN1517090A (zh) * 2003-01-20 2004-08-04 王玉万 含抗菌药物的兽用混悬注射剂或乳剂
WO2010102196A2 (en) * 2009-03-05 2010-09-10 Insite Vision Incorporated Controlled-release ophthalmic vehicles

Also Published As

Publication number Publication date
SV2014004882A (es) 2016-11-11
HRP20191730T1 (hr) 2019-12-13
MY172561A (en) 2019-12-03
MX387668B (es) 2025-03-18
HUE046427T2 (hu) 2020-03-30
KR102113822B1 (ko) 2020-05-22
EP2874624A4 (en) 2015-12-02
DK2874624T3 (da) 2019-11-11
JP2015522608A (ja) 2015-08-06
BR112014031083B1 (pt) 2021-06-15
RU2643327C2 (ru) 2018-01-31
IL236713B (en) 2018-05-31
ZA201409322B (en) 2015-12-23
AU2013290826A1 (en) 2015-01-15
LT2874624T (lt) 2019-12-10
UA118654C2 (uk) 2019-02-25
IL236713A0 (en) 2015-02-26
NI201400152A (es) 2015-03-27
CL2014003423A1 (es) 2015-04-17
EP2874624B8 (en) 2019-10-02
PH12014502716A1 (en) 2015-02-02
PT2874624T (pt) 2019-11-04
CN104470517A (zh) 2015-03-25
PL2874624T3 (pl) 2020-07-27
MX358248B (es) 2018-08-10
WO2014014363A1 (en) 2014-01-23
BR112014031083A2 (pt) 2017-06-27
CR20140550A (es) 2015-02-05
AU2013290826B2 (en) 2018-10-18
EP2874624A1 (en) 2015-05-27
MX2014015927A (es) 2015-03-03
PH12014502716B1 (en) 2015-02-02
CA2875351C (en) 2021-08-31
US20150174248A1 (en) 2015-06-25
CO7240359A2 (es) 2015-04-17
DOP2014000288A (es) 2015-02-15
SI2874624T1 (sl) 2020-02-28
JP6189437B2 (ja) 2017-08-30
US10376585B2 (en) 2019-08-13
RU2015105251A (ru) 2016-09-10
CA2875351A1 (en) 2014-01-23
KR20150036092A (ko) 2015-04-07
ES2752034T3 (es) 2020-04-02
EP2874624B1 (en) 2019-08-21

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Effective date of registration: 20250801

Address after: Oakland, New Zealand

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