CN104398889A - Traditional Chinese medicine composition capable of expelling phlegm and arresting coughing and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition capable of expelling phlegm and arresting coughing and preparation method of traditional Chinese medicine composition Download PDFInfo
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- CN104398889A CN104398889A CN201410703213.0A CN201410703213A CN104398889A CN 104398889 A CN104398889 A CN 104398889A CN 201410703213 A CN201410703213 A CN 201410703213A CN 104398889 A CN104398889 A CN 104398889A
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Abstract
The invention discloses a traditional Chinese medicine composition capable of expelling phlegm and arresting coughing and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared by mixing raw radix astragali, raw gypsum, lalang grass rhizome, liquorice, Chinese yam, raw radix rehmanniae, rhizoma anemarrhenae, radix scrophulariae, radix adenophorae, bulbus fritillariae cirrhosae and fructus arctii according to a certain ratio. The traditional Chinese medicine composition has the effects of clearing heat, moistening lung, preventing phlegm from forming and stopping coughing, dispelling wind and heat, releasing lung and promoting eruption, is quick in effect, few in side effects and low in cost; meanwhile, the traditional Chinese medicine composition has the practical effect of treating cough with profuse sputum caused by a plurality of respiratory diseases.
Description
Technical field
The present invention relates to a kind of is Chinese medicine composition of crude drug and preparation method thereof by Chinese herbal medicine, relates to Chinese medicine composition of a kind of expelling phlegm for arresting cough and preparation method thereof specifically.
Background technology
Respiratory system disease is a kind of commonly encountered diseases, frequently-occurring disease, shows as abundant expectoration, cough, hypopnea, itching throat, pharyngalgia, nasal obstruction, watery nasal discharge clinically more.Western medicine is mainly with antiinflammatory and be equipped with antibiotics to treat, but side effect is larger, especially antibiotic, and antibiotic abuse can cause more serious drug resistance, and the cough that some bronchitis of going slowly causes is unsuitable life-time service antibiotic therapy also.Chinese medicine, is started with from disease, the cause of disease two aspects by being familiar with more fully respectively to the pathomechanism of cough, abundant expectoration, in the treatment to cough, abundant expectoration disease, have obvious advantage.
Summary of the invention
The present invention, from clinical treatment medication demand and the dialectical principle of traditional Chinese medical science prescription, proposes Chinese medicine composition of a kind of expelling phlegm for arresting cough and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Radix Astragali 12-18g, Gypsum Fibrosum 12-18g, Rhizoma Imperatae 12-18g, Radix Glycyrrhizae 3-9g, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-9g, Radix Rehmanniae 3-8g, Rhizoma Anemarrhenae 3-5g, Radix Scrophulariae 3-8g, Radix Adenophorae (Radix Glehniae) 3-8g, Bulbus Fritillariae Cirrhosae 3-8g, Fructus Arctii 3-8g.Optimum ratio is: Radix Astragali 15g, Gypsum Fibrosum 15g, Rhizoma Imperatae 15g, Radix Glycyrrhizae 6g, RHIIZOMA DIOSCOREAE fr0m Henan of China 6g, Radix Rehmanniae 5g, Rhizoma Anemarrhenae 3g, Radix Scrophulariae 5g, Radix Adenophorae (Radix Glehniae) 5g, Bulbus Fritillariae Cirrhosae 3g, Fructus Arctii 3g.Described medicament is decoction, capsule, tablet or pill.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Radix Astragali, Gypsum Fibrosum, Rhizoma Imperatae, Radix Glycyrrhizae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae, Fructus Arctii pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
the pharmacology of traditional Chinese medicinal composition raw materials of the present invention is as follows:
Radix Astragali: have and have yang invigorating, strengthening superficial resistance to stop perspiration, evacuation of pus granulation promoting, inducing diuresis to remove edema, the effect of antiabortive beneficial blood.Cure mainly syndrome of deficiency of lung qi: cough with asthma with the passing of time, shortness of breath and tired spirit.
Gypsum Fibrosum: [curing mainly] apoplexy cold and heat, heart subinverse gas is frightened to be breathed heavily, and xerostomia scorching tongue, can not cease, hardness and fullness in the abdomen pain, evil removing ghost, puerperium incised wound.Except seasonal epidemic pathogens headache fever of the body, three burnt large heat, skin heat, stagnation of QI in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, restlessness accompanied by ascending of QI of only quenching one's thirst, the sudden and violent gas of abdominal distention, pharynx heat of panting.
Rhizoma Imperatae: cure mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing.For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat is vomitted the sound of vomiting, coughs.
Radix Glycyrrhizae: feeble QI, taste is sweet and special.Function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.
RHIIZOMA DIOSCOREAE fr0m Henan of China: being evaluated as " temperature compensation " " property is put down " by always doctor, is the model of " integration of edible and medicinal herbs ".
Radix Rehmanniae: nature and flavor: sweetness and bitterness is cool.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
The Rhizoma Anemarrhenae: property bitter cold, has nourishing YIN to lower pathogenic fire, moisturizes laxation, the effect of sharp defecation.Gunpowder under genus heat clearing away, cures mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst.
Radix Scrophulariae: there is clearing away heat and cooling blood; Nourishing YIN to lower pathogenic fire; Effect of detoxicating and resolving stagnation of pathogens.Main warm febrile disease and nutrient blood; Fever of the body; Excessive thirst; Crimson tongue; Send out speckle; Hectic fever due to YIN-deficiency chronic cough; Fidgets due to deficiency is awake not; Constipation is hindered in Tianjin; Order is puckery dim-sighted; Throat larynx swells and ache; Scrofula sucutaneous nodule; Skin sore.
Radix Adenophorae (Radix Glehniae): sweet in the mouth; Micro-hardship; Cold nature; Return lung; Stomach warp.There is clearing away heat and nourishing YIN, effect of nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.
Bulbus Fritillariae Cirrhosae: property is bitter, sweet, is slightly cold.Return lung, heart channel.There are clearing heat and moistening lung, the function of preventing phlegm from forming and stopping coughing.
Fructus Arctii: there is dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, effect of removing toxic substances and promoting subsidence of swelling.
The present invention is with Radix Astragali, Gypsum Fibrosum, Rhizoma Imperatae for monarch drug, and for yang invigorating, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, cold relieving heat, expelling pathogenic factors from muscles by diaphoresis, restlessness accompanied by ascending of QI of only quenching one's thirst, pharynx of panting is hot, cooling blood for hemostasis, heat-clearing and toxic substances removing.With Radix Glycyrrhizae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Radix Rehmanniae, Radix Scrophulariae, Radix Adenophorae (Radix Glehniae) for ministerial drug, expelling phlegm for arresting cough, temperature compensation health, controls fever due to yin deficiency, clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, detoxicating and resolving stagnation of pathogens, clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Assistant makes with the Rhizoma Anemarrhenae, Bulbus Fritillariae Cirrhosae, Fructus Arctii, to moisturize laxation, clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling.Chinese medicine composition of the present invention holds the marrow of the traditional Chinese medical science, rigorous prescription, and all medicine monarch share, and mends broken combination, brings out the best in each other, meet the principle of traditional Chinese medical science medicine law and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
beneficial effect
Chinese medicine composition of the present invention can clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, dispelling wind and heat pathogens, lung qi dispersing rash, and have practical curative effect, instant effect to the cough with copious phlegm that the various respiratory tract disease for the treatment of causes, side effect is little, and price is low.
non-clinical statistical data
1, case screening
2011-2013 upper respiratory tract infection and acute bronchitis patient 432 example.
2, diagnostic criteria
Upper respiratory tract infection clinical symptoms: heating, nasal obstruction, watery nasal discharge, sneeze, laryngopharynx swelling and pain, antiadoncus, hyperemia, cough, extremities aching pain etc.
3, therapeutic scheme
Decoction in embodiment 2 side, day potion that is decocted in water for oral dose takes at twice, within 7 days, is a course for the treatment of.
4, the standard of curative effect evaluation
Cure: resolution of fever, pharyngeal inflammation disappears, and cough with copious phlegm symptom disappears;
Effective: resolution of fever, pharyngeal inflammation alleviates, and cough alleviates, and expectorant tails off;
Invalid: symptom is unchanged, or increase the weight of
Total effective rate=cure rate+effective percentage.
5, statistical result
| Case load | Cure | Effectively | Invalid | Cure rate | Total effective rate |
| 432 examples | 372 | 114 | 6 | 86.11% | 98.61% |
6, conclusion
Extract cough with copious phlegm case 432 example that 2011-2013 application we treatment upper respiratory tract infection causes, find through statistics, cure 372 examples, cure rate reaches 86.11%, effective 114 examples, and invalid 6 examples, total effective rate reaches 98.61%.We, through clinical trial for many years and use, have practical curative effect to the cough with copious phlegm that treatment upper respiratory tract infection causes.
acute toxicity test:larger dose and take to the growth of rat without remarkable toxicity compared with long-term therapy, have no overt toxicity damage to the chip form inspection such as brain, the heart, liver, kidney of rat and change, test display, this Chinese medicine composition toxicity is very little.
Detailed description of the invention
embodiment 1:chinese medicine composition of a kind of expelling phlegm for arresting cough and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Radix Astragali 12-18g, Gypsum Fibrosum 12-18g, Rhizoma Imperatae 12-18g, Radix Glycyrrhizae 3-9g, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-9g, Radix Rehmanniae 3-8g, Rhizoma Anemarrhenae 3-5g, Radix Scrophulariae 3-8g, Radix Adenophorae (Radix Glehniae) 3-8g, Bulbus Fritillariae Cirrhosae 3-8g, Fructus Arctii 3-8g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Radix Astragali 12-18g, Gypsum Fibrosum 12-18g, Rhizoma Imperatae 12-18g, Radix Glycyrrhizae 3-9g, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-9g, Radix Rehmanniae 3-8g, Rhizoma Anemarrhenae 3-5g, Radix Scrophulariae 3-8g, Radix Adenophorae (Radix Glehniae) 3-8g, Bulbus Fritillariae Cirrhosae 3-8g, Fructus Arctii 3-8g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Radix Astragali, Gypsum Fibrosum, Rhizoma Imperatae, Radix Glycyrrhizae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae, Fructus Arctii pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
embodiment 2:chinese medicine composition of a kind of expelling phlegm for arresting cough and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Radix Astragali 15g, Gypsum Fibrosum 15g, Rhizoma Imperatae 15g, Radix Glycyrrhizae 6g, RHIIZOMA DIOSCOREAE fr0m Henan of China 6g, Radix Rehmanniae 5g, Rhizoma Anemarrhenae 3g, Radix Scrophulariae 5g, Radix Adenophorae (Radix Glehniae) 5g, Bulbus Fritillariae Cirrhosae 3g, Fructus Arctii 3g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Radix Astragali 15g, Gypsum Fibrosum 15g, Rhizoma Imperatae 15g, Radix Glycyrrhizae 6g, RHIIZOMA DIOSCOREAE fr0m Henan of China 6g, Radix Rehmanniae 5g, Rhizoma Anemarrhenae 3g, Radix Scrophulariae 5g, Radix Adenophorae (Radix Glehniae) 5g, Bulbus Fritillariae Cirrhosae 3g, Fructus Arctii 3g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Radix Astragali, Gypsum Fibrosum, Rhizoma Imperatae, Radix Glycyrrhizae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae, Fructus Arctii pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
Embodiment 3, medicine of the present invention can also be decoction, oral liquid, granule etc.
Claims (5)
1. a Chinese medicine composition for expelling phlegm for arresting cough, is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Radix Astragali 12-18g, Gypsum Fibrosum 12-18g, Rhizoma Imperatae 12-18g, Radix Glycyrrhizae 3-9g, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-9g, Radix Rehmanniae 3-8g, Rhizoma Anemarrhenae 3-5g, Radix Scrophulariae 3-8g, Radix Adenophorae (Radix Glehniae) 3-8g, Bulbus Fritillariae Cirrhosae 3-8g, Fructus Arctii 3-8g.
2. the Chinese medicine composition of expelling phlegm for arresting cough according to claim 1, is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Radix Astragali 15g, Gypsum Fibrosum 15g, Rhizoma Imperatae 15g, Radix Glycyrrhizae 6g, RHIIZOMA DIOSCOREAE fr0m Henan of China 6g, Radix Rehmanniae 5g, Rhizoma Anemarrhenae 3g, Radix Scrophulariae 5g, Radix Adenophorae (Radix Glehniae) 5g, Bulbus Fritillariae Cirrhosae 3g, Fructus Arctii 3g.
3. the Chinese medicine composition of expelling phlegm for arresting cough according to claim 1 and 2, is characterized in that: described medicament is decoction, capsule, tablet or pill.
4. the Chinese medicine composition of expelling phlegm for arresting cough according to claim 3, is characterized in that: the preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Radix Astragali, Gypsum Fibrosum, Rhizoma Imperatae, Radix Glycyrrhizae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae, Fructus Arctii pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
5. the preparation method of the Chinese medicine composition of expelling phlegm for arresting cough according to claim 4, is characterized in that the mixture described in step (2), and the number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
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Application publication date: 20150311 |