CN104825778A - Traditional Chinese medicine composition for treating calf pneumonia - Google Patents
Traditional Chinese medicine composition for treating calf pneumonia Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating calf pneumonia. The traditional Chinese medicine composition comprises, by weight, 120+/-10 parts of gypsum, 60+/-5 parts by weight of coptis root, 50+/-5 parts of pilose asiabell root, 50+/-5 parts of raw Hangzhou white peony root, 40+/-4 parts of pinellia ternate, 40+/-4 parts of cortex magnoliae officinalis, 40+/-4 parts of radix ophiopogonis, 40+/-4 parts of rhizoma belamcandae, 30+/-3 parts of fruit of Chinese magnoliavine, 50+/-5 parts of bulbus fritillariae cirrhosae and 30+/-3 parts of licorice root. The traditional Chinese medicine composition has functions of clearing heat and removing toxins, clearing lung heat and relieving cough, eliminating sputum and relieving asthma, strengthening body resistance and eliminating evil, removing qi fire and cooling blood, has no toxic or side effect, is suitable for pestilence toxic heat and inner fire symptoms and can be used for calf pneumonia treatment.
Description
Technical field
The invention belongs to veterinary drug technical field, be specifically related to a kind of Chinese medicine composition being used for the treatment of calf pneumonia.
Background technology
Calf pneumonia Chinese veterinarian claims this sick for lung is yellow, is calf commonly encountered diseases.Chinese veterinarian's theory thinks that lung is subject to the disease caused by pathogenic heat.Clinical manifestation is heating, sweating, the body temperature rising of calf, calf inappetence or absolutely useless, breathes with cough, breathes symptoms such as urging.Chinese veterinarian thinks that calf pneumonia can be caused by reasons such as affection due to external wind and heat, epidemic disease, wind and cold, rheumatism.At the beginning of disease, exopathogen violates lung, and disease sees that mild nasal congestion glues tears, cough, heating.Pathogenic factor is not understood and is then occurred accumulation of heat in the lung, clear respectful mistake department, abnormal rising of lung-QI, and body temperature raises, and cough out of breath, expectorant is turbid, and it is unfavorable to breathe, and dehisces to pant, and stretches neck and raises head, and listen to have and breathe rale sound, night more very.The course of disease further develops, and occurs that stagnant heat is hot and suffocating, and QI rising in reverse order expectorant is stopped up, and vehemently in pyretic toxicity hinders in lung network, consumption impairment of body fluid liquid, is shown in stagnation of QI-blood, coughs up and tell thick sputum band blood, have fishy smell, disease sees disease calf expectoration volume mucus or bloodysputum liquid, and the congested swelling of pharyngolaryngeal mucosa, is above coated with pseudomembrane, thirst and liking drink water.Control and should detoxify, clearing away lung-heat, relieving cough and asthma.Modern medicine study is thought and to be caused primarily of antibacterial, mycoplasma and virus etc.At present, the common drug for the treatment of calf pneumonia uses antibiotic.But there is problem such as generation drug resistance, drug residue etc. in long-term a large amount of antibiotic that uses.
Summary of the invention
The invention provides a kind of Chinese medicine composition being used for the treatment of calf pneumonia, to calf pneumonia, there is good therapeutic effect, and there is not the problem such as drug resistance, drug residue.
The invention provides a kind of Chinese medicine composition being used for the treatment of calf pneumonia, described Chinese medicine composition is made up of following crude drug: Gypsum Fibrosum 120 ± 10 weight portion, Rhizoma Coptidis 60 ± 5 weight portion, Radix Codonopsis 50 ± 5 weight portion, raw Radix Paeoniae Alba 50 ± 5 weight portion, the Rhizoma Pinelliae 40 ± 4 weight portion, Cortex Magnoliae Officinalis 40 ± 4 weight portion, Radix Ophiopogonis 40 ± 4 weight portion, Rhizoma Belamcandae 40 ± 4 weight portion, Fructus Schisandrae Chinensis 30 ± 3 weight portion, Bulbus Fritillariae Cirrhosae 50 ± 5 weight portion, Radix Glycyrrhizae 30 ± 3 weight portion.
Preferably, described Chinese medicine composition is made up of following crude drug: Gypsum Fibrosum 120 weight portion, Rhizoma Coptidis 60 weight portion, Radix Codonopsis 50 weight portion, raw Radix Paeoniae Alba 50 weight portion, the Rhizoma Pinelliae 40 weight portion, Cortex Magnoliae Officinalis 40 weight portion, Radix Ophiopogonis 40 weight portion, Rhizoma Belamcandae 40 weight portion, Fructus Schisandrae Chinensis 30 weight portion, Bulbus Fritillariae Cirrhosae 50 weight portion, Radix Glycyrrhizae 30 weight portion.
Under above-mentioned optimum condition, the best results for the treatment of calf pneumonia.
Second object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition, is to pulverize after each crude drug mixing by formula ratio to prepare.
Second object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition, is that after each crude drug mixing by formula ratio, water extraction obtains.
3rd object of the present invention is to provide the application of above-mentioned Chinese medicine composition in the medicine of preparation treatment calf pneumonia.
4th object of the present invention is to provide a kind of medicine, and its effective ingredient is the Chinese medicine composition described in claim 1 or 2.
Preferably, medically acceptable adjuvant is also comprised.
Further, the dosage form of described medicine is oral liquid, tablet, pill, granule, unguentum.
In Chinese medicine composition of the present invention:
Gypsum Fibrosum: pungent, sweet, is slightly cold.Attach to the lung and stomach meridians, have clearing away heat-fire, effect that relieving restlessness is quenched the thirst.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder large intestine channel.There is heat clearing and damp drying, effect of eliminating fire and detoxication.The kind fire separating the part of the body cavity above the diaphragm housing the heart and lungs.
Radix Codonopsis: sweet, flat.Enter spleen, lung meridian.There is invigorating the spleen and replenishing QI, effect of nourishing blood to promote the production of body fluid.
Raw Radix Paeoniae Alba: be slightly cold is bitter, sour.Function is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
The Rhizoma Pinelliae: pungent, temperature.Return spleen, stomach, lung meridian.Function is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention.
Cortex Magnoliae Officinalis: bitter, pungent; Warm in nature, return spleen, stomach, large intestine channel.Function is circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.QI rising in reverse order is stopped up for expectorant; Fullness in the chest is breathed with cough.
Radix Ophiopogonis: feeble QI is fragrant, sweet in the mouth, micro-hardship.GUIXIN, lung, stomach warp.Function is YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.For dryness of the lung dry cough, sore throat pharyngalgia, Tianjin wound is thirsty.
Rhizoma Belamcandae: bitter in the mouth, cold in nature, micro-poison.Enter lung, Liver Channel.There is effect of heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature.Return lung, the heart, kidney channel.There is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.
Bulbus Fritillariae Cirrhosae: sweet in the mouth, flat, cool in nature, returns lung meridian, stomach warp.Function is removing heat-phlegm, nourishing the lung to arrest cough, dissipating depression of QI eliminating stagnation.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
Radix Glycyrrhizae: property is flat, taste is put down. enter the heart, lung, spleen, stomach warp.Have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, remove phlegm and relieving cough, effect of relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Fang Xie: Chinese medicine composition of the present invention is with Gypsum Fibrosum, pungent sweet Great Cold, clear eliminating the pathogens from the lung heat, reduce phlegm relieve coughing, promoting the production of body fluid to quench thirst, is monarch drug; Rhizoma Coptidis (eliminating fire and detoxication) helps the clear eliminating the pathogens from the lung heat of Gypsum Fibrosum, separates the toxin of pestilence of the part of the body cavity above the diaphragm housing the heart and lungs; More be aided with the pungent knot that scatters of the Rhizoma Pinelliae, lowering the adverse-rising QI and eliminating phlegm, the Cortex Magnoliae Officinalis therapeutic method to keep the adverse QI flowing downwards is loose full, reduces phlegm and unwinds, Bulbus Fritillariae Cirrhosae removing heat-phlegm, nourishing the lung to arrest cough.Raw Radix Paeoniae Alba astringing YIN to stop sweating, Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, hold concurrently while nourishing the lung to arrest cough helps Gypsum Fibrosum lung heat clearing excess-heat can lung-yin nourishing, reducing phlegm unwinds cough-relieving, above all medicines are ministerial drug.Be adjuvant drug with Rhizoma Belamcandae (heat-clearing and toxic substances removing, relieving cough and resolving phlegm), Fructus Schisandrae Chinensis (restraining astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid), because of Gypsum Fibrosum energy lung heat clearing relieve coughing, and assistant more can sharp expectorant Dingchuan with two medicines.Using Radix Glycyrrhizae person, is for alleviating under all medicine of a cold natures, not for its cold and cool infringement part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, for making medicine.The person that uses Radix Codonopsis, is strengthening vital QI to eliminate pathogenic factors, prevents body void from the pathogenic heat hidden for a long time in body just can be made to go out.
All side's compatibilities, obtain Chinese medicine composition of the present invention.Show through relevant experiment, Chinese medicine composition of the present invention has heat-clearing and toxic substances removing, the function of lung heat clearing relieve coughing, sharp expectorant Dingchuan, strengthening vital QI to eliminate pathogenic factors, can the fire that divides of clearing heat in QI system, again can the removing heat from blood heat of dividing, there is good antipyretic and antidote functions, and Chinese medicine composition of the present invention is without toxicity, be applicable to pestilence pyretic toxicity and all burning hot cards, can be used for the treatment of calf pneumonia.
Detailed description of the invention
Following embodiment is convenient to understand the present invention better, but does not limit the present invention.Experimental technique in following embodiment, if no special instructions, is conventional method.Test material used in following embodiment, if no special instructions, is and purchases available from routine biochemistry reagent shop.
embodiment 1
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 24Kg, Rhizoma Coptidis 12Kg, Radix Codonopsis 10Kg, raw Radix Paeoniae Alba 10Kg, Rhizoma Pinelliae 8Kg, Cortex Magnoliae Officinalis 8Kg, Radix Ophiopogonis 8Kg, Rhizoma Belamcandae 8Kg, Fructus Schisandrae Chinensis 6Kg, Bulbus Fritillariae Cirrhosae 10Kg, Radix Glycyrrhizae 6Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Accurately take each medicine according to aforementioned proportion, drying is pulverized, and crosses 60 mesh sieves, mixing, subpackage.
embodiment 2
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 110Kg, Rhizoma Coptidis 55Kg, Radix Codonopsis 55Kg, raw Radix Paeoniae Alba 45Kg, Rhizoma Pinelliae 36Kg, Cortex Magnoliae Officinalis 44Kg, Radix Ophiopogonis 36Kg, Rhizoma Belamcandae 36Kg, Fructus Schisandrae Chinensis 27Kg, Bulbus Fritillariae Cirrhosae 55Kg, Radix Glycyrrhizae 33Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Each medicine is accurately taken, water extraction 2 rear mixing and get final product according to aforementioned proportion.
embodiment 3
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 130Kg, Rhizoma Coptidis 65Kg, Radix Codonopsis 45Kg, raw Radix Paeoniae Alba 55Kg, Rhizoma Pinelliae 44Kg, Cortex Magnoliae Officinalis 36Kg, Radix Ophiopogonis 44Kg, Rhizoma Belamcandae 44Kg, Fructus Schisandrae Chinensis 33Kg, Bulbus Fritillariae Cirrhosae 45Kg, Radix Glycyrrhizae 27Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Each medicine is accurately taken, water extraction 3 rear mixing and get final product according to aforementioned proportion.
embodiment 4
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 125Kg, Rhizoma Coptidis 62Kg, Radix Codonopsis 45Kg, raw Radix Paeoniae Alba 55Kg, Rhizoma Pinelliae 40Kg, Cortex Magnoliae Officinalis 38Kg, Radix Ophiopogonis 44Kg, Rhizoma Belamcandae 44Kg, Fructus Schisandrae Chinensis 33Kg, Bulbus Fritillariae Cirrhosae 48Kg, Radix Glycyrrhizae 28Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Accurately take each medicine according to aforementioned proportion, drying is pulverized, and crosses 60 mesh sieves, mixing, subpackage.
embodiment 5
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 115Kg, Rhizoma Coptidis 58Kg, Radix Codonopsis 48Kg, raw Radix Paeoniae Alba 45Kg, Rhizoma Pinelliae 42Kg, Cortex Magnoliae Officinalis 38Kg, Radix Ophiopogonis 42Kg, Rhizoma Belamcandae 42Kg, Fructus Schisandrae Chinensis 28Kg, Bulbus Fritillariae Cirrhosae 48Kg, Radix Glycyrrhizae 29Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Each medicine is accurately taken, water extraction 3 rear mixing and get final product according to aforementioned proportion.
embodiment 6
The Traditional Chinese medicine composition formula being used for the treatment of calf pneumonia of the present invention is as follows:
Gypsum Fibrosum 118Kg, Rhizoma Coptidis 65Kg, Radix Codonopsis 45Kg, raw Radix Paeoniae Alba 51Kg, Rhizoma Pinelliae 44Kg, Cortex Magnoliae Officinalis 39Kg, Radix Ophiopogonis 44Kg, Rhizoma Belamcandae 41Kg, Fructus Schisandrae Chinensis 31Kg, Bulbus Fritillariae Cirrhosae 53Kg, Radix Glycyrrhizae 31Kg.
The Chinese medicine composition preparation method being used for the treatment of calf pneumonia of the present invention is as follows:
Accurately take each medicine according to aforementioned proportion, drying is pulverized, and crosses 60 mesh sieves, mixing, subpackage.
the toxicity test of embodiment 7 Chinese medicine composition of the present invention:
In order to the toxic and side effects of clear and definite Chinese medicine composition of the present invention, to making accurately its safety, objective appraisal, for clinical trial medication provides scientific basis, guaranteeing clinical drug safety, having carried out toxicity test of the present invention.
By carrying out LD of the present invention to mice
50show with mtd test, after design dosage oral administration, in 7 days, each group mice behavior sign is normal, does not all occur poisoning symptom and death.Therefore cannot LD be measured
50, and have to maximum dosage-feeding 86g/kg for maximum dose level.After within 8th day, slaughtering, each group mice organs is all without pathological changes, and liver,kidney,spleen histological examination, does not find pathological characters yet.Hemogram and serum GPT Activity determination, result and normal mouse there was no significant difference.
In order to grasp the toxicity and the order of severity that produce because using Chinese medicine composition of the present invention continuously, and development after drug withdrawal and recovery situation, reference is provided for drafting data for clinical drug use dosage, rat has carried out subacute toxicity test of the present invention: high, medium and low dosage group rat respectively by 30 g/(kgbw), 15 g/(kgbw), 3 g/(kgbw) (according to crude drug, dosage gastric infusion down together), control rats gavages normal saline, every 24 h are administered once, continuous 30 d.
Within experimental period, except high dose group affects ingest because drug dose causes greatly palatability difference, all the other respectively organize rat diet, behavior, feces is all normal, physically well develops, without any poisoning symptom, weightening finish and nutrition except high dose group and matched group significant difference, all the other there are no significant differences.The hemogram of each group and serum GPT are all in normal range.Histological examination, liver,kidney,spleen etc. are all without obvious poisoning pathological changes.Doubly to feed 30d by the 5-10 of clinical application amount, also have no toxic and side effects, illustrate that the clinical medicine dose of said preparation is very safe.
the clinical effect trial of embodiment 8 Chinese medicine composition of the present invention
Artificial challenge viral dosage research shows, the calf pneumonia of Induced by Endotoxin of the present invention has obvious therapeutic action, obviously can suppress heating (average reduction temperature 1 DEG C), improve blood change, the whole blood contrast viscosity of laboratory animal obviously reduces with the ratio of reduction whole blood contrast viscosity, significantly can shorten erythrocyte electrophoretic time, but packed cell volume and erythrocyte sedimentation rate are had no significant effect.Reduce mortality rate, extend the time-to-live; PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM shows, the present invention has protection internal organs, alleviates the effect of pathological lesion.
The present invention adopts random double blind test method to carry out various dose (high dose group 150g/ head, middle dosage group 75g/ head, low dose group 30g/ head) and treats natural occurrence calf pneumonia Clinical Treatment Test, and selects florfenicol to be positive drug control group.Observe the present invention to calf pneumonia therapeutical effect, to inquire into the feasibility that it applies in Production of Livestock and Poultry.
diagnostic criteria
The Clinical symptoms of calf pneumonia is that spirit is depressed, appetite declines, and body temperature raises; Lie prostrate in ground, cough, frequency of respiration increase, in ventral breathing, auscultation pulmonary have dryness or moist rales serious time draw bellows like mouth breathing, cough in various degree, dyspnea is exhaustion even.Analyse and be changed to lobus cardiacus, the dorsal part of sharp leaf and the front end meat sample pathological changes of diaphragm leaf, pulmonary's connective tissue proliferation, there is Catarrhal secretions in trachea.Hilar lymph node and lung mediastinal lymph node enlargement, quality is hardening.
administering mode
Calculate dosage according to sick calf body weight, after test medicine and a little concentrate are mixed thoroughly, allow disease calf naturally search for food and take medicine; To the sick calf of taking medicine that can not naturally search for food, after a little mixing that added water by test medicine, gavage administration.Every day at the upper and lower noon feed before each administration 1 time, successive administration 7d, continues after drug withdrawal to observe 3d.After administration, tested calf lets alone free choice feeding, drinking-water.
observation index
During clinical trial, namely before administration, during administration and after drug withdrawal in 3d, the cough number of times of observed and recorded every day 1 tested calf, breathe increase that whether obvious number, asthma is, whether poor appetite or enhancement, body temperature increase, the General Symptoms such as spiritual, whether occur that death and pathology such as to analyse at the situation.
therapeutic outcome
To the treatment of natural occurrence calf pneumonia disease, high, middle dosage treatment group cure rate is 92.5%, mortality rate, and aggregate efficiency is 5%, 95.0% respectively.The high, medium and low dosage of the present invention has therapeutical effect to calf pneumonia disease, and energy relief of symptoms, reduces mortality rate, and height, middle dosage are at reduction mortality rate, and the effect improving the aspects such as cure rate and florfenicol is suitable.High, middle dosage the present invention can reach the effect of survival rate of curing the disease, improve, and both zero differences in 0.05 level, therefore dosage in can adopting during Clinical practice, so not only economic curative effect but also remarkable.
From result of the test, the present invention has heat-clearing and toxic substances removing, the functions such as lung heat clearing relieve coughing, sharp expectorant Dingchuan, strengthening vital QI to eliminate pathogenic factors.In clinical trial process, do not find that this medicine has untoward reaction.High, medium and low dosage has good therapeutic effect to calf pneumonia, and the effect of high, middle dosage to therapeutic effect and florfenicol is suitable.The therapeutic effect of low dose group lower than high, middle dosage group, middle and high dosage group there are no significant in mortality rate, cure rate and total effective rate difference.Should according to the weight of the state of an illness and treatment cost, with middle dosage, (calf 50 ~ 100g every day, is used in conjunction 3 ~ 5 days in suggestion clinical practice; Or mixed feeding, every 1kg feedstuff 10 ~ 20g) as well, be used in conjunction 3 ~ 5 days.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. one kind is used for the treatment of the Chinese medicine composition of calf pneumonia, it is characterized in that: described Chinese medicine composition is made up of following crude drug: Gypsum Fibrosum 120 ± 10 weight portion, Rhizoma Coptidis 60 ± 5 weight portion, Radix Codonopsis 50 ± 5 weight portion, raw Radix Paeoniae Alba 50 ± 5 weight portion, the Rhizoma Pinelliae 40 ± 4 weight portion, Cortex Magnoliae Officinalis 40 ± 4 weight portion, Radix Ophiopogonis 40 ± 4 weight portion, Rhizoma Belamcandae 40 ± 4 weight portion, Fructus Schisandrae Chinensis 30 ± 3 weight portion, Bulbus Fritillariae Cirrhosae 50 ± 5 weight portion, Radix Glycyrrhizae 30 ± 3 weight portion.
2. Chinese medicine composition according to claim 1, it is characterized in that: described Chinese medicine composition is made up of following crude drug: Gypsum Fibrosum 120 weight portion, Rhizoma Coptidis 60 weight portion, Radix Codonopsis 50 weight portion, raw Radix Paeoniae Alba 50 weight portion, the Rhizoma Pinelliae 40 weight portion, Cortex Magnoliae Officinalis 40 weight portion, Radix Ophiopogonis 40 weight portion, Rhizoma Belamcandae 40 weight portion, Fructus Schisandrae Chinensis 30 weight portion, Bulbus Fritillariae Cirrhosae 50 weight portion, Radix Glycyrrhizae 30 weight portion.
3. the preparation method of the Chinese medicine composition described in claim 1 or 2, is characterized in that: be pulverize after each crude drug mixing by formula ratio to prepare.
4. the preparation method of the Chinese medicine composition described in claim 1 or 2, is characterized in that: be that after each crude drug mixing by formula ratio, water extraction obtains.
5. the application of the Chinese medicine composition described in claim 1 or 2 in the medicine of preparation treatment calf pneumonia.
6. a medicine, its effective ingredient is the Chinese medicine composition described in claim 1 or 2.
7. medicine according to claim 6, is characterized in that: also comprise medically acceptable adjuvant.
8. medicine according to claim 6, is characterized in that: the dosage form of described medicine is oral liquid, tablet, pill, granule, unguentum.
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| CN105311511A (en) * | 2015-11-03 | 2016-02-10 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicinal composition for treating pneumonia in calves as well as preparation method and application of traditional Chinese medicinal composition |
| CN109223958A (en) * | 2018-11-10 | 2019-01-18 | 莫章刑 | A kind of Chinese medicine preparation treated ox and lose disease out |
| CN116270843A (en) * | 2023-03-24 | 2023-06-23 | 克拉玛依绿成农业开发有限责任公司 | Traditional Chinese medicine composition for treating calf mycoplasma pneumonia and application thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311511A (en) * | 2015-11-03 | 2016-02-10 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicinal composition for treating pneumonia in calves as well as preparation method and application of traditional Chinese medicinal composition |
| CN105250786A (en) * | 2015-11-17 | 2016-01-20 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine for treating calf pneumonia |
| CN109223958A (en) * | 2018-11-10 | 2019-01-18 | 莫章刑 | A kind of Chinese medicine preparation treated ox and lose disease out |
| CN116270843A (en) * | 2023-03-24 | 2023-06-23 | 克拉玛依绿成农业开发有限责任公司 | Traditional Chinese medicine composition for treating calf mycoplasma pneumonia and application thereof |
| CN116270843B (en) * | 2023-03-24 | 2024-06-25 | 克拉玛依绿成农业开发有限责任公司 | Traditional Chinese medicine composition for treating calf mycoplasma pneumonia and application thereof |
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