CN104398610A - Medicament for treating cough and preparation method thereof - Google Patents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention relates to a medicament for treating cough and a preparation method thereof. The medicament is prepared from folium mori, the root bark of white mulberry, almond, rhizoma bolbostemmae, scutellaria baicalensis, aster, periostracum cicada and liquorice through compatibility, can resist bacteria and diminish inflammation, clear lung-heat and moisten dryness, relieve cough and asthma, remove heat and reduce phlegm and remove toxicity for detumescence, has a better curative effect of treating cough with lung heat and excessive phlegm, which are caused by related inflammation, and has small toxic or side effects.
Description
Technical field
The present invention relates to a kind of is Chinese medicine composition of crude drug and preparation method thereof by Chinese herbal medicine, relates to a kind of medicine for the treatment of cough and preparation method thereof specifically.
Background technology
Doctor trained in Western medicine is thought: cough is the protectiveness respiratory reflex action that human body removes secretions in respiratory tract or foreign body.Cough is many by upper respiratory tract infection or bronchitis etc., causes the inflammation of upper respiratory tract mucosa and causes.
The traditional Chinese medical science is thought: cough is because of diseases caused by exogenous pathogenic factor six climate exopathogens, internal organs internal injury, affects the sound disease having expectorant caused by the lung.See " Plain Questions the five internal organs generate a section "." Plain Questions pathogenesis gas should save one's life collection ": " cough meaning sound without expectorant, lung qi is hindered and also unclear; It is noiseless and have expectorant for coughing, spleen wet dynamic and be expectorant also.Cough meaning has expectorant and sound, and lid moves in lung qi due to wound and wets in spleen, cough and for coughing also ".Because exopathogen violates lung, or internal organs internal injury, involves caused by the lung.
Cough (Cough) is although be a kind of protectiveness respiratory reflex action of human body.Effectively can remove the secretions in respiratory tract by coughre flex or enter the foreign body of air flue.But cough also has disadvantageous one side, violent cough can cause respiratory tract hemorrhage, and as a long time, frequently, violent cough affects work, has a rest, even causes laryngalgia, hoarseness and breathing myalgia.
Summary of the invention
The present invention, from clinical treatment medication demand and the dialectical principle of traditional Chinese medical science prescription, proposes a kind of medicine for the treatment of cough due to lung-heat and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Folium Mori 3-13g, Cortex Mori 12-18g, Semen Armeniacae Amarum 3-13g, Rhizoma Bolbostematis 3-13g, Radix Scutellariae 3-13g, Radix Asteris 3-13g, Periostracum Cicadae 3-9g, Radix Glycyrrhizae 3-8g.Optimum ratio is: Folium Mori 10g, Cortex Mori 15g, Semen Armeniacae Amarum 10g, Rhizoma Bolbostematis 10g, Radix Scutellariae 10g, Radix Asteris 10g, Periostracum Cicadae 6g, Radix Glycyrrhizae 5g.Described medicament is decoction, capsule, tablet or pill.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Folium Mori, Cortex Mori, Semen Armeniacae Amarum, Rhizoma Bolbostematis, Radix Scutellariae, Radix Asteris, Periostracum Cicadae, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
the pharmacology of medicine material medicine of the present invention is as follows:
Folium Mori: in the modern times, doctor trained in Western medicine uses Folium Mori and Folium Mori biological preparation as the medicine improving diabetes and other various difficult miscellaneous diseases, thinks that its drug effect is very extensive.There are clearing away lung-heat and moistening for dryness, cough-relieving, reduce phlegm and internal heat, reduce phlegm, control night sweat; Tonifying liver, liver heat removing and eyesight improving, treatment dizziness and blurred vision, insomnia, elimination eye strain; Detumescence, purify the blood ' treatment dysentery, stomachache, fat-reducing, except beriberi, sharp large and small intestinal; Anti-stress, removing heat from blood, blood pressure lowering, blood fat reducing, prevention myocardial infarction, cerebral hemorrhage, dispel headache, long hair; Blood sugar lowering, anti-sugar are sick.
Cortex Mori: Cortex Mori is the dry root bark of moraceae plants Mulberry (Classification system: Morus alba L.).Another name Cortex Mori, Radix Mori skin, Cortex Mori, Morus alba skin.Main product in Anhui, Henan, Zhejiang, Jiangsu, the ground such as Hunan.Modern medicine confirms, Cortex Mori has the effect of blood pressure lowering, diuresis, sedation and analgesia, antiinflammatory, antibacterial, anticoagulant.There is antipyretic, expelling phlegm for arresting cough effect preferably.
Semen Armeniacae Amarum: bitter, tepor; Slightly poisonous.There is relieving cough and asthma, effect of relaxing bowel.
Rhizoma Bolbostematis: [return through]: return lung, spleen channel, [function]: eliminating stagnation, detumescence, removing toxic substances.[curing mainly]: for acute mastitis, scrofula; Mastitis, lymphoid tuberculosis, chronic lymphadenitis, hypertrophic rhinitis.
Radix Scutellariae: Gui Jing: enter the heart, lung, gallbladder, large intestine channel.Cure mainly: removing the relative excess fire, except damp and hot, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leak, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.
Radix Asteris: nature and flavor: bitter, temperature.Function cures mainly: warming the lung, the therapeutic method to keep the adverse QI flowing downwards, expectorant, cough-relieving.Control cough due to wind and cold's asthma, asthenia coughs vomiting bloody pus, sore throat, dysuria.Pharmacological action: (1) phlegm-dispelling functions: the traditional Chinese medical science thinks that Radix Asteris has warming the lung, the therapeutic method to keep the adverse QI flowing downwards, the function that expectorant, cough-relieving are coughed.Experiment shows, water decoction has phlegm-dispelling functions and without antitussive and antiasthmatic effect; Benzene and methanolic extract also have phlegm-dispelling functions.(2) antibacterial action: Radix Asteris has certain inhibitory action to 7 kinds of Gram-negative enteral pathogenic bacterium such as escherichia coli, dysentery bacterium, mycetozoan, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus and vibrio cholera in vitro; And have the effect of antagonism pathogenic fungus.(3) antivirus action: water decoction infected by influenza in chick embryo allantois has obvious inhibitory action.(4) the effect of Tumor suppression: it is reported that isolated epifriedelanol has tumor-inhibiting action to mice ehrlich carcinoma; Also report is had to have anti-tumor activity from the isolated cyclic peptide compound of the n-Butanol fractoion of tatarian aster root to S180.
Periostracum Cicadae: [meridian distribution of property and flavor] is sweet, cold.Return lung, Liver Channel.[function cures mainly] falls apart wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Radix Glycyrrhizae: feeble QI, taste is sweet and special.Function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.
The present invention take Cortex Mori as monarch drug, for antihypertensive diuretic, sedation and analgesia, anti-inflammation.With Folium Mori, Semen Armeniacae Amarum, Rhizoma Bolbostematis, Radix Scutellariae, Radix Asteris for ministerial drug, clearing away lung-heat and moistening for dryness, relieving cough and asthma, reduces phlegm and internal heat and reduces phlegm, removing toxic substances and promoting subsidence of swelling, the warming the lung therapeutic method to keep the adverse QI flowing downwards, stopping coughing and removing phlegm.Help with Periostracum Cicadae, make with Radix Glycyrrhizae, loose wind heat extraction, sore-throat relieving rash, nebula removing spasmolytic, heat-clearing and toxic substances removing, expelling phlegm for arresting cough.Medicine of the present invention holds the marrow of the traditional Chinese medical science, rigorous prescription, and all medicine monarch share, and mends broken combination, brings out the best in each other, meet the principle of traditional Chinese medical science medicine law and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
beneficial effect
Chinese medicine composition energy anti-inflammation of the present invention, clearing away lung-heat and moistening for dryness, relieving cough and asthma, reduces phlegm and internal heat and reduces phlegm, removing toxic substances and promoting subsidence of swelling, have good therapeutic effect, and toxic and side effects is little to cough due to lung-heat, the abundant expectoration that the relevant inflammation for the treatment of causes.
non-clinical statistical data
1, case screening
2011-2013 clinical case 273 example.
2, screening criteria
Cough but no phlegm or the few dry cough of amount of expectoration; Or cough is with the moist cough of expectoration;
Patient suffers from flu, bronchitis, and occasionally occur together heat.
3, therapeutic scheme
Take medicine decoction of the present invention, according to embodiment 2 prescription, day potion that is decocted in water for oral dose takes at twice, within 7 days, is a course for the treatment of.
4, the standard of curative effect evaluation
Cure: cough transference cure, inflammation disappears;
Effective: cough symptom alleviates, and inflammation alleviates;
Invalid: symptom variation is very micro-, or increases the weight of;
Total effective rate=cure rate+effective percentage.
5, statistical result
| Case load | Cure | Effectively | Invalid | Cure rate | Total effective rate |
| 273 examples | 239 examples | 31 examples | 3 | 87.55% | 98.90% |
6, conclusion
The curative effect routine cough patients of 2011-2013 273 being applied to the treatment of this prescription is added up, and cure 239 altogether, cure rate is 87.55%, effective 31 examples, and invalid 3 examples, total effective rate reaches 98.90%.
Medicine of the present invention is through clinical trial for many years and use, and to treatment because cough, abundant expectoration that the inflammation such as flu, bronchitis causes have practical curative effect, effectively can treat cough, treatment is quick, and effective, toxic and side effects is little.
acute toxicity test:larger dose and take to the growth of rat without remarkable toxicity compared with long-term therapy, have no overt toxicity damage to the chip form inspection such as brain, the heart, liver, kidney of rat and change, test display, this drug toxicity is very little.
Detailed description of the invention
embodiment 1:a kind of medicine for the treatment of cough and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Folium Mori 3-13g, Cortex Mori 12-18g, Semen Armeniacae Amarum 3-13g, Rhizoma Bolbostematis 3-13g, Radix Scutellariae 3-13g, Radix Asteris 3-13g, Periostracum Cicadae 3-9g, Radix Glycyrrhizae 3-8g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Folium Mori 3-13g, Cortex Mori 12-18g, Semen Armeniacae Amarum 3-13g, Rhizoma Bolbostematis 3-13g, Radix Scutellariae 3-13g, Radix Asteris 3-13g, Periostracum Cicadae 3-9g, Radix Glycyrrhizae 3-8g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Folium Mori, Cortex Mori, Semen Armeniacae Amarum, Rhizoma Bolbostematis, Radix Scutellariae, Radix Asteris, Periostracum Cicadae, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
embodiment 2:a kind of medicine for the treatment of cough and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Folium Mori 10g, Cortex Mori 15g, Semen Armeniacae Amarum 10g, Rhizoma Bolbostematis 10g, Radix Scutellariae 10g, Radix Asteris 10g, Periostracum Cicadae 6g, Radix Glycyrrhizae 5g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Folium Mori 10g, Cortex Mori 15g, Semen Armeniacae Amarum 10g, Rhizoma Bolbostematis 10g, Radix Scutellariae 10g, Radix Asteris 10g, Periostracum Cicadae 6g, Radix Glycyrrhizae 5g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Folium Mori, Cortex Mori, Semen Armeniacae Amarum, Rhizoma Bolbostematis, Radix Scutellariae, Radix Asteris, Periostracum Cicadae, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
Embodiment 3, medicine of the present invention can also be decoction, oral liquid, granule etc.
Claims (5)
1. treat a medicine for cough, it is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Folium Mori 3-13g, Cortex Mori 12-18g, Semen Armeniacae Amarum 3-13g, Rhizoma Bolbostematis 3-13g, Radix Scutellariae 3-13g, Radix Asteris 3-13g, Periostracum Cicadae 3-9g, Radix Glycyrrhizae 3-8g.
2. the medicine for the treatment of cough according to claim 1, is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Folium Mori 10g, Cortex Mori 15g, Semen Armeniacae Amarum 10g, Rhizoma Bolbostematis 10g, Radix Scutellariae 10g, Radix Asteris 10g, Periostracum Cicadae 6g, Radix Glycyrrhizae 5g.
3. the medicine for the treatment of cough according to claim 1 and 2, is characterized in that: described medicament is decoction, capsule, tablet or pill.
4. the medicine for the treatment of cough according to claim 3, is characterized in that: the preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Folium Mori, Cortex Mori, Semen Armeniacae Amarum, Rhizoma Bolbostematis, Radix Scutellariae, Radix Asteris, Periostracum Cicadae, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
5. the preparation method of the medicine for the treatment of cough according to claim 4, it is characterized in that the mixture described in step (2), the number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410703248.4A CN104398610A (en) | 2014-11-29 | 2014-11-29 | Medicament for treating cough and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105126054A (en) * | 2015-08-28 | 2015-12-09 | 许五妮 | Traditional Chinese medicine for treating cough with lung heat |
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2014
- 2014-11-29 CN CN201410703248.4A patent/CN104398610A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105126054A (en) * | 2015-08-28 | 2015-12-09 | 许五妮 | Traditional Chinese medicine for treating cough with lung heat |
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Application publication date: 20150311 |
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