CN104398635A - Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof - Google Patents

Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof Download PDF

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Publication number
CN104398635A
CN104398635A CN201410714811.8A CN201410714811A CN104398635A CN 104398635 A CN104398635 A CN 104398635A CN 201410714811 A CN201410714811 A CN 201410714811A CN 104398635 A CN104398635 A CN 104398635A
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traditional chinese
chinese medicine
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sheep
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刘志辉
李琳
曲荟芬
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Sky Agriculture (tianjin) Biological Technology Co Ltd
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Sky Agriculture (tianjin) Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicinal composition for treating acute ruminal tympany of sheep. The traditional Chinese medicinal composition is prepared from cortex magnoliae officinalis, rhubarb, fructus aurantii immaturus, pericarpium citri reticulatae viride, medicated leaven, hawthorn, inula flower and red orche and can be powder. The traditional Chinese medicinal composition can be prepared by the following steps: firstly, weighing the traditional Chinese medicines according to the formula, wherein the cortex magnoliae officinalis accounts for 20-40 parts, the rhubarb accounts for 20-40 parts, the fructus aurantii immaturus accounts for 20-40 parts, the pericarpium citri reticulatae viride accounts for 20-40 parts, the medicated leaven accounts for 20-40 parts, the hawthorn accounts for 20-40 parts, the inula flower accounts for 20-40 parts and the red orche accounts for 20-40 parts; secondly, crushing the traditional Chinese medicines, and enabling the traditional Chinese medicines to pass through a sieve with 40-80 meshes; thirdly, mixing the traditional Chinese medicines to obtain traditional Chinese medicinal powder; fourthly, respectively packaging the traditional Chinese medicinal powder according to the dose of 100-200g for each bag to obtain a finished product. The traditional Chinese medicinal composition provided by the invention can be used for effectively treating the acute ruminal tympany of the sheep with the cure rate of over 95 percent, and has the effects of relieving stagnant qi, removing stagnation and improving appetite and promoting digestion.

Description

A kind ofly treat Chinese medicine composition of the acute ruminal tympany of sheep and preparation method thereof
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind ofly treat Chinese medicine composition of the acute ruminal tympany of sheep and preparation method thereof.
Background technology
Acute ruminal tympany be forage at rumen zymosis, produce a large amount of gas, cause cud volume to increase rapidly, excessive expansion also occurs that belch obstacle is a kind of disease of feature.Often betide spring, summer, sheep and goat all can be ill.Primary disease can be divided into constitutional ruminal tympany (spumescence distension gas) and Secondary cases ruminal tympany (non-foam property or free gas distension gas) two kinds.Constitutional ruminal tympany: mainly contain raw spumescence material in eaten herbage, as Saponin, pectin, hemicellulose, particularly soluble leaf proteins, rumen zymosis gas is made to generate foam stable in a large number and mix with rumen content, be not excluded by belch, cause bloat.In addition, the grain trough that more pulverizing of searching for food is meticulous, can cause rumen pH to decline, when being suitable for the bacterial growth being with pod membrane, antibacterial can produce the extracellular polysaccharide mucus of stable foam, and salivation is insufficient, also plays an important role in constitutional ruminal tympany.Under the cooperation of these factors, distension gas can be triggered at any moment.In putting into practice, primary disease is more common in following situations.
1. eaten the feedstuff of a large amount of easily fermentation it is a risk that various Papilionaceae plant, as clover, Herba Medicaginis and other leguminous plants, especially before blooming.Herd the early spring in the luxuriant pasture of grass, or polyphagia wither dry grass, pulverize meticulous concentrate, the Rhizoma Solani tuber osi of mouldy corruption, Radix Dauci Sativae and Rhizoma Dioscoreae class and all easily fall ill.
2. eaten pasture and water after rain or the not dry grass of dew, freezing feedstuff or withered stalk be when especially after summer rain, early morning herds, easily suffers from that this is sick.
Secondary cases ruminal tympany mainly due to glandular stomach miopragia, belch malfunction.Be more common in forestomach atony, esophageall obstruetion, peritonitis, choke disease etc.Sick sheep plants oneself, and rear arch rises, and head often bends towards abdominal part.Soon abdominal part swells rapidly, and the left side is more obvious, and skin is nervous, kowtow as drum.Because first stomach extrudes to thoracic cavity, cause dyspnea, sick sheep dehisces to loll, and shows very painful.Dyspneic reason except due to except gastric gas savings, simultaneously also because first stomach can absorbing carbon dioxide and carbon monoxide rapidly.When expanding serious, the conjunctiva of sick sheep and other visible mucosas are aubergine, and do not eat, do not ruminate, pulse is fast and weak, have belch or regurgitation of food phenomenon; Sometimes rectum hangs down de-.This seasonal disease sheep is very poverty-stricken, astasia, finally lies down on the ground, spasm and dead.The course of disease is everlasting 1 hours.
Necropsy abdominal part expands.Cud wall is at full stretch, and cud or diaphragm break sometimes.Gastric has a large amount of gas or foam-like material.Lung or venous congestion, pericardium and serous coat (pleura) have little point-like and wire hyperemia, resemble pathological changes of suffocating very much.
Current clinical common method adopts the methods such as massage, Western medicine diarrhoea, inducing QI, larger to the intestines and stomach damage.Therefore develop a tcm product, accomplish treating both the exterior and interior, clinical meaning is extremely important.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of evident in efficacy, cure rate is high, side effect is low Chinese medicine composition.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula for the treatment of the acute ruminal tympany of sheep.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of the acute ruminal tympany of sheep, is characterized in that: be prepared from by the raw material of following mass fraction: Cortex Magnoliae Officinalis 20-40 part, Radix Et Rhizoma Rhei 20-40 part, Fructus Aurantii Immaturus 20-40 part, Pericarpium Citri Reticulatae Viride 20-40 part, Massa Medicata Fermentata 20-40 part, Fructus Crataegi 20-40 part, Flos Inulae 20-40 part, Haematitum 20-40 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: Cortex Magnoliae Officinalis 30 parts, Radix Et Rhizoma Rhei 20 parts, Fructus Aurantii Immaturus 30 parts, 30 parts, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 20 parts, Fructus Crataegi 30 parts, Flos Inulae 30 parts, Haematitum 40 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is:
(1) each Chinese medicine is taken by formula ratio, wherein, Cortex Magnoliae Officinalis 20-40 part, Radix Et Rhizoma Rhei 20-40 part, Fructus Aurantii Immaturus 20-40 part, Pericarpium Citri Reticulatae Viride 20-40 part, Massa Medicata Fermentata 20-40 part, Fructus Crataegi 20-40 part, Flos Inulae 20-40 part, Haematitum 20-40 part; (2) Chinese medicine is pulverized, cross 40-80 mesh sieve; (3) mix 10-20 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is got product by every bag of 100-200g subpackage.
The advantage that the present invention has and good effect are:
(1) this prescription is according to tcm theory, scientific compatibility, have dispelling the stagnated QI disappear painful abdominal mass, capture and let out effect that is long-pending, invigorating the stomach and promoting digestion, through clinical verification determined curative effect, cure rate can reach more than 95%, the Chinese medicine preparation simultaneously obtained according to this prescription have evident in efficacy, side effect is low, the advantage of environmental protection.
(2) pharmacology of each raw material of Chinese medicine of the present invention is:
Radix Et Rhizoma Rhei: purge heat poison, and removing mass is stagnant, clots absorbing blood;
Fructus Aurantii Immaturus: dispelling the stagnated QI falls apart painful abdominal mass, removing food stagnancy;
Cortex Magnoliae Officinalis: circulation of qi promoting removing food stagnancy, dampness is except full;
Fructus Crataegi: spleen benefiting and stimulating the appetite, relieving dyspepsia;
Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant;
Massa Medicata Fermentata: promoting digestion and removing stagnation, invigorating the spleen and regulating the stomach;
Flos Inulae: dissolving lump and resolving mass, stopping nausea and vomiting by lowering the adverse flow of QI;
Haematitum: important city sending down the abnormal ascending QI;
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Treat a Chinese powder medicine for the acute ruminal tympany of sheep, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 30 parts, Radix Et Rhizoma Rhei 20 parts, Fructus Aurantii Immaturus 30 parts, 30 parts, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 20 parts, Fructus Crataegi 30 parts, Flos Inulae 30 parts, Haematitum 40 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 15 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is got product by every bag of 200g subpackage.
Embodiment 2
Treat a Chinese powder medicine for the acute ruminal tympany of sheep, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 40 parts, Radix Et Rhizoma Rhei 20 parts, Fructus Aurantii Immaturus 30 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 20 parts, Fructus Crataegi 30 parts, Flos Inulae 30 parts, Haematitum 40 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 15 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is got product by every bag of 200g subpackage.
Embodiment 3
Treat a Chinese powder medicine for the acute ruminal tympany of sheep, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 30 parts, Radix Et Rhizoma Rhei 40 parts, Fructus Aurantii Immaturus 30 parts, 40 parts, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 30 parts, Fructus Crataegi 30 parts, Flos Inulae 30 parts, Haematitum 40 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 15 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is got product by every bag of 200g subpackage.
Clinical trial
Experiment 1:
Inner Mongol province sheep raiser breeding sheep 10000, wherein 3000 there is acute ruminal tympany.Wherein 2000 spices product of feeding obtained by embodiment 1.Dosage presses 100g spice 100kg, feeds 3 days continuously.Abdominal distention disappears, and occur without dead, two Zhou Houwu repeatedly.Cure rate 100%.Other 1000 use Oleum Terebinthinae to gavage, and after two weeks, 80% sick sheep occurs repeatedly.More than illustrate that product obtained by embodiment 1 is used for the treatment of the acute ruminal tympany of sheep evident in efficacy and be better than the similar Western medicine product in market.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.

Claims (6)

1. one kind is used for the treatment of the Chinese medicine composition of the acute ruminal tympany of sheep, it is characterized in that, be prepared from by the raw material of following mass fraction: Cortex Magnoliae Officinalis 20-40 part, Radix Et Rhizoma Rhei 20-40 part, Fructus Aurantii Immaturus 20-40 part, Pericarpium Citri Reticulatae Viride 20-40 part, Massa Medicata Fermentata 20-40 part, Fructus Crataegi 20-40 part, Flos Inulae 20-40 part, Haematitum 20-40 part.
2. the Chinese medicine composition of the acute ruminal tympany for the treatment of sheep according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Cortex Magnoliae Officinalis 30 parts, Radix Et Rhizoma Rhei 20 parts, Fructus Aurantii Immaturus 30 parts, 30 parts, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 20 parts, Fructus Crataegi 30 parts, Flos Inulae 30 parts, Haematitum 40 parts.
3. the Chinese medicine composition of the acute ruminal tympany for the treatment of sheep according to claim 3, is characterized in that: described preparation can be powder.
4. prepare a method for the Chinese medicine composition of the acute ruminal tympany for the treatment of sheep as claimed in claim 3, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized and sieved; (3) Chinese medicine powder is mixed; (4) subpackage gets product.
5. the preparation method of the Chinese medicine composition of the acute ruminal tympany for the treatment of sheep according to claim 4, is characterized in that: Chinese medicine is pulverized as 40-80 order.
6. the preparation method of the Chinese medicine composition of the acute ruminal tympany for the treatment of sheep according to claim 4, is characterized in that: packing specification is 100-200g/ bag.
CN201410714811.8A 2014-11-29 2014-11-29 Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof Pending CN104398635A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940872A (en) * 2015-06-13 2015-09-30 施瑞客(天津)生物技术有限公司 Traditional Chinese medicine composition for treating equine intestinal tympany and preparation method thereof
CN106139087A (en) * 2016-08-09 2016-11-23 黄平县皓泽牧业养殖发展有限公司 One is treated sheep and is bloated Chinese medicine formula

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258735A (en) * 2011-07-23 2011-11-30 山西双鹰动物药业有限公司 Medicine for treating fore-stomach stony and impaction of rumen in cows and preparation method thereof
CN103316124A (en) * 2013-05-21 2013-09-25 南京市中医院 Application of raw rhubarb composition in bowel relaxing, qi regulating, and intestinal recovery

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258735A (en) * 2011-07-23 2011-11-30 山西双鹰动物药业有限公司 Medicine for treating fore-stomach stony and impaction of rumen in cows and preparation method thereof
CN103316124A (en) * 2013-05-21 2013-09-25 南京市中医院 Application of raw rhubarb composition in bowel relaxing, qi regulating, and intestinal recovery

Non-Patent Citations (3)

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Title
刘海: "反刍家畜前胃疾病的综合诊治", <<科学种养>> *
刘艳花: "牛瘤胃臌气的综合诊治", <<中国畜禽种业>> *
陈良金等: "枳实消痞汤治疗功能性消化不良47例疗效观察", <<新中医>> *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940872A (en) * 2015-06-13 2015-09-30 施瑞客(天津)生物技术有限公司 Traditional Chinese medicine composition for treating equine intestinal tympany and preparation method thereof
CN106139087A (en) * 2016-08-09 2016-11-23 黄平县皓泽牧业养殖发展有限公司 One is treated sheep and is bloated Chinese medicine formula

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