CN102258735A - Medicine for treating fore-stomach stony and impaction of rumen in cows and preparation method thereof - Google Patents
Medicine for treating fore-stomach stony and impaction of rumen in cows and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating fore-stomach stony and impaction of rumen in cows, which is prepared from the following Chinese herbal medicines serving as raw material medicines in part by weight: 55 to 65 parts of hawthorn, 55 to 65 parts of medicated leaven, 55 to 65 parts of malt, 35 to 45 parts of radish seed, 55 to 65 parts of dried orange peel, 55 to 65 parts of areca nut, 25 to 35 parts of bitter orange, 25 to 35 parts of nutgrass galingale rhizome, 25 to 35 parts of katsumade galangal seeds and 115 to 125 parts of compound of glaubersalt and liquorice. The powder of the medicine disclosed by the invention is prepared by crushing the Chinese medicinal raw materials, sieving and mixing. The medicine disclosed by the invention is suitable for treating diseases in cows, including fore-stomach stony, impaction of rumen, bloating in rumen and the like, and has the characteristics of quick effectiveness, good treatment effect, no medicine residue and no toxic nor side effects.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of milch cow forestomach atony and grainsick, particularly relating to a kind of is the treatment milch cow forestomach atony made of raw material and the medicine of grainsick with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
Milch cow forestomach atony and grainsick are owing to the disorder of glandular stomach neuroregulation, the disease of a kind of digestive function obstacle due to preceding coat of the stomach irritability reduction and contractility weaken.Be divided into constitutional and Secondary cases according to the reason that causes, be divided into acutely and chronic according to the course of disease of disorder, be the milch cow regular incidence.Constitutional forestomach atony and grainsick mainly cause owing to feeding and management is improper.Modal is that feedstuff is simple, feed for a long time be difficult to digest, be rich in coarse-fibred feedstuff, feed quality bad and modulate improper, as mouldy Radix Glycyrrhizae, corrupt mould bad tuber, freezing rotten sweet potato etc., the intense stimulus coat of the stomach, especially under the situation of subimbition, preceding gastric content easily entangles the block that Chan becomes to be difficult to swallow, and influences the digestion activity of rumen microorganism; Otherwise, when feeding soft tiny for a long time or lacking irritating feedstuff (as wheat bran, flour, concentrate in small, broken bits etc.), be not enough to excited glandular stomach function, all easily cause forestomach atony.The forage (as rotten grass, ensilage, distiller grains, the Glycine max (L.) Merr. etc. of fermenting) that the quality of feeding is bad, or the unexpected conversion of forage, glandular stomach function are difficult for adapting to for the moment, also are the reasons that causes forestomach atony.In addition, calcium level reduction, miscarriage such as excessive usage or hypomotility etc. also are the inducements that causes the constitutional forestomach atony.Cattle forestomach atony clinical symptoms has acute and chronic two kinds of situations, chronic forestomach atony and grainsick majority are by acute forestomach atony and grainsick development, when acute forestomach atony and grainsick do not heal for a long time, cud, omasum and abomasum inflammation, necrosis, traumatic reticulitis and other diseases such as liver abscess, johne's disease etc. all can cause the appearance of chronic forestomach atony and grainsick.
The symptom that acute forestomach atony mainly shows is that appetite, drinking-water go down, and then most to suffer from the cattle appetite useless exhausted, ruminates unablely, and number of times reduces, even stops.The rumen peristalsis sound weakens or disappears; Reticulum and omasum peristaltic sound also weaken; The cud palpation, its content is soft, occurs intermittent distension gas sometimes.Their early stage, feces changes not obvious, and feces is hard subsequently, color dark, epidermis is surrounded by mucus, during secondary enteritis, row's sepia medicated porridge sample or watery stools.Chronic forestomach atony symptom clinically is with acute similar, but the course of disease is long, and patient's condition is slow, and it is depressed that sick cattle often shows as spirit, the asoscope drying, and loss of appetite or disappearance, are differently had a liking for monophagia, often grind one's teeth in sleep, and ruminate and belch reduces, and the gas that goes out is with stench.The rumen peristalsis sound weakens or disappears, and the palpation content is soft or be glutinous hard sense, sees chronic mild ruminal tympany more.The intestinal sound significantly weakens, and defecation is sluggish, and the stiff color of feces is dark, is black peat shape or row's stench loose stool.Along with the development of the state of an illness, become thin gradually, anemia, disorderly thick by hair, xerosis cutis, enophthalmos,enophthalmus, the asoscope be full of cracks, even do not rise with crouching.
Use antibiotic, the also reports of useful Chinese herbal treatment when in the prior art, treating milch cow forestomach atony and grainsick disease more.Employing antibiotic therapy effect is better, but residual at milk easily, influences the quality of milk, reaches the food-safety problem to consumer.Contain multiple nutrients composition and native chemical composition in the Chinese herbal medicine, as vitamin, mineral, trace element etc., its effect is many target spots, when preventing and curing diseases, can also growth promotion, increasing the immune function of animal, improve the animal economy resistance against diseases, is the unification of nutritive value and medical value.In the today of advocating pollution-free food energetically, the disadvantages such as potential hazard that the drug residue that antibiotic etc is brought in aquaculture reaches ecological environment have become clear day by day, cause the vigilant of people, and advantages such as the toxic and side effects of Chinese herbal medicine is little, difficult generation drug resistance are that antibiotic and chemical synthetic drug are incomparable.In recent years, add Chinese herbal medicine and replace antibiotic research more and more in feedstuff, the inventor is that the medicine that feedstock production is treated milch cow forestomach atony and grainsick has carried out years of researches with Chinese herbal medicine, has obtained obvious effects.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of milch cow forestomach atony and grainsick, its curative effect is fast, good effect, and the medicine of non-evident effect, and the present invention also extracts the preparation method of this medicine.
The medicine of treatment milch cow forestomach atony of the present invention and grainsick is the compositions that is prepared by following Chinese herbal medicine materials in weight portion medicine: Fructus Crataegi 55-65, Massa Medicata Fermentata 55-65, Fructus Hordei Germinatus 55-65, Semen Raphani 35-45, Pericarpium Citri Reticulatae 55-65, Semen Arecae 55-65, Fructus Aurantii 25-35, Rhizoma Cyperi 25-35, Semen Alpiniae Katsumadai 25-35, Matrii Sulfas Exsiccatus 115-125.
Further, the preferred weight portion of each crude drug is in the medicine of the present invention: Fructus Crataegi 60, Fructus Hordei Germinatus 60, Massa Medicata Fermentata 60, Semen Raphani 40, Pericarpium Citri Reticulatae 60, Semen Arecae 60, Rhizoma Cyperi 30, Semen Alpiniae Katsumadai 30, Fructus Aurantii 30, Matrii Sulfas Exsiccatus 120.
Said medicine can be made pill on the pharmaceutics, oral liquid, powder etc., consider that clinical practice is easy to use, be reluctant to search for food after the animal morbidity, practical situation such as product stability, preferred dosage form is a powder.
The preparation method of drug powder of the present invention is as follows: take by weighing a certain amount of each raw material of Chinese medicine by above-mentioned weight portion, be powder through pulverizing, sieve, mixing.
In the prescription of the present invention, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Semen Raphani dyspepsia and intestinal stasis relieving are monarch drug, hawthorn digesting eliminate indigestion, dissipating blood stasis, Massa Medicata Fermentata eating accumulation, dyspepsia, the Fructus Hordei Germinatus facilitating digestion, blood sugar lowering, Semen Raphani eliminating indigested food, regulating stomach-QI, the chest stuffiness relieving diaphragm, turbid, the blood pressure lowering of eliminating the phlegm, dissipating blood stasis blood, logical stool.Pericarpium Citri Reticulatae, Semen Arecae, Fructus Aurantii, Rhizoma Cyperi, the Semen Alpiniae Katsumadai promoting qi circulation, resolving food retention, regulating QI to relieve pain is a ministerial drug, the Pericarpium Citri Reticulatae dampness of regulating the flow of vital energy, the Semen Arecae the spleen strengthening and damp drying, promoting the circulation of QI to induce diuresis, removing food stagnancy, the Fructus Aurantii regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, the Rhizoma Cyperi resolving depression of regulating the flow of vital energy, promoting blood circulation and stopping pain, Semen Alpiniae Katsumadai is drying damp and strengthening spleen, the stomach warming preventing or arresting vomiting, the Matrii Sulfas Exsiccatus expelling pathogenic heat to loosen the bowels, moistening for dryness and softening hard mass, the detumescence of relieving inflammation or internal heat, cure mainly the excess-heat constipation, feces is constipated, stagnant stomachache, comprehensively above medicine is aid digestion, promote gastrointestinal peristalsis, sharp liver and gall, the pain relieving relieving distension, the function of relieving constipation by purgation is removed forestomach atony, appetite is useless exhausted, ruminate the symptom that stops.
The medicine of treatment milch cow forestomach atony of the present invention and grainsick is applicable to diseases such as milch cow forestomach atony, grainsick, ruminal tympany, and large-scale application proves that curative effect is fast, good effect.Medicine of the present invention belongs to pure Chinese medicinal preparation, compares no drug residue with Western medicine, has no side effect.
The clinical treatment test report: 90 milch cows that forestomach atony, grainsick, ruminal tympany occur and ruminate clinical symptoms such as unable have been carried out therapeutic test with medicine of the present invention, and matched group is the digestive powder that certain company produces.
Ill milch cow totally 90, is Fresian, cow 58 examples of wherein growing up, growing cattle 22 examples, calf 10 examples from Changzhi City suburb, Shanxi Province and small towns.Course of disease weak point person went to a doctor in 1-2 days, and the elder went to a doctor about 5 days.Clinical symptoms shows as that appetite reduces or is useless exhausted, ruminates to weaken or stop, and it is not normal to press the rumen content soft durometer, and the gastric peristalsis sound weakens, and number of times reduces, and the persistent period shortens and even disappears, and left the part between the ribs and the hips sink, and abdominal part expands.In 90 sick cattle, be diagnosed as 44 examples that have of forestomach atony, be diagnosed as 26 examples that have of grainsick, be diagnosed as 20 examples that have of ruminal tympany.
Respectively half is treated with medicine of the present invention and control drug with the sick cattle of various diseases.Medicine of the present invention is got 120 parts of 60 parts of Fructus Crataegis, 60 parts in Fructus Hordei Germinatus, 60 parts of Massa Medicata Fermentata, 40 parts of Semen Raphanis, 60 parts of Pericarpium Citri Reticulataes, 60 parts of Semen Arecaes, 30 parts of Rhizoma Cyperis, 30 parts of Semen Alpiniae Katsumadai, 30 parts of Fructus Aurantiis and Matrii Sulfas Exsiccatus, through pulverizing, sieving, mix, be prepared into powder, dosage, the calf of powder of the present invention by the adult cattle of 500g/ head reduced by half, the powder that is good for the stomach reduces by half with dosage, the calf of the adult cattle of 250g/ head respectively, reconstitute with boiled water, wait temperature and gavage.
Acute case morbidity medication 2 days, chronic case (promptly fall ill and just went to a doctor later in many days) medication 5 days, gavage once every day.No matter be processed group or matched group, for serious grainsick and ruminal tympany, for strengthening the neuroregulation effect, recover the fore-stomach movement function, use 10% sodium chloride injection 300-500ml, 10% calcirm chloride inj 100-200ml, 10% caffeine and sodium benzoate injection 20ml simultaneously, an intravenous injection when sick cattle has acidosis symptom, is used 5% sodium bicarbonate injection 500-1000ml intravenous injection.
Treatment standard: ruminate with the mental status and appetite and recover normal for curing cure rate=healing number/treatment sum; Ruminate with the mental status and appetite take an evident turn for the better for effectively, effective percentage=healings number+significant figure/treatment is total.
Result of the test sees Table 1, table 2.
Result of the test shows, medicine of the present invention is 82.2% to the cure rate of milch cow forestomach atony and grainsick, effective percentage is 95.6%, and the cure rate of contrast is 44.4%, effective percentage is 62.2%, analyze by statistics, the cure rate of medicine of the present invention and effective percentage comparison all are utmost point significant difference (P ﹤ 0.01) according to medicine.Illustrate that medicine of the present invention is from clinical efficacy, to the therapeutic effect of milch cow forestomach atony and grainsick significantly better than control drug, and have characteristics of curative effect fast (acute case morbidity medication 2 days, chronic case medication 5 days), good effect (cure rate is 82.2%, and effective percentage is 95.6%).
The specific embodiment
Embodiment 1
Get 11.5 kilograms of 5.5 kilograms of Fructus Crataegis, 5.5 kilograms of Massa Medicata Fermentata, 5.5 kilograms in Fructus Hordei Germinatus, 3.5 kilograms of Semen Raphanis, 5.5 kilograms of Pericarpium Citri Reticulataes, 6.5 kilograms of Semen Arecaes, 3.5 kilograms of Fructus Aurantiis, 3.5 kilograms of Rhizoma Cyperis, 3.5 kilograms of Semen Alpiniae Katsumadai and Matrii Sulfas Exsiccatus, will pulverize, sieve, mix the drug powder that is treatment milch cow forestomach atony and grainsick.
Embodiment 2
Get 12.5 kilograms of 6.5 kilograms of Fructus Crataegis, 6.5 kilograms of Massa Medicata Fermentata, 6.5 kilograms in Fructus Hordei Germinatus, 4.5 kilograms of Semen Raphanis, 6.5 kilograms of Pericarpium Citri Reticulataes, 5.5 kilograms of Semen Arecaes, 2.5 kilograms of Fructus Aurantiis, 2.5 kilograms of Rhizoma Cyperis, 2.5 kilograms of Semen Alpiniae Katsumadai and Matrii Sulfas Exsiccatus, will pulverize, sieve, mix the drug powder that is treatment milch cow forestomach atony and grainsick.
Embodiment 3
Get 12 kilograms of 6 kilograms of Fructus Crataegis, 6 kilograms of Massa Medicata Fermentata, 6 kilograms in Fructus Hordei Germinatus, 4 kilograms of Semen Raphanis, 6 kilograms of Pericarpium Citri Reticulataes, 6 kilograms of Semen Arecaes, 3 kilograms of Fructus Aurantiis, 3 kilograms of Rhizoma Cyperis, 3 kilograms of Semen Alpiniae Katsumadai and Matrii Sulfas Exsiccatus, will pulverize, sieve, mix the drug powder that is treatment milch cow forestomach atony and grainsick.
Claims (2)
1. medicine for the treatment of milch cow forestomach atony and grainsick, be the compositions for preparing by following Chinese herbal medicine materials in weight portion medicine: Fructus Crataegi 55-65, Massa Medicata Fermentata 55-65, Fructus Hordei Germinatus 55-65, Semen Raphani 35-45, Pericarpium Citri Reticulatae 55-65, Semen Arecae 55-65, Fructus Aurantii 25-35, Rhizoma Cyperi 25-35, Semen Alpiniae Katsumadai 25-35, Matrii Sulfas Exsiccatus 115-125, pulverize each raw material of Chinese medicine, sieve, mix and be powder.
2. a kind of medicine for the treatment of milch cow forestomach atony and grainsick according to claim 1, it is characterized in that the weight portion of each crude drug is: Fructus Crataegi 60, Fructus Hordei Germinatus 60, Massa Medicata Fermentata 60, Semen Raphani 40, Pericarpium Citri Reticulatae 60, Semen Arecae 60, Rhizoma Cyperi 30, Semen Alpiniae Katsumadai 30, Fructus Aurantii 30, Matrii Sulfas Exsiccatus 120.
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Cited By (11)
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| CN102599387A (en) * | 2012-03-23 | 2012-07-25 | 蒋勇 | Traditional Chinese medicine additive for fattening cattle and applications thereof |
| CN103948685A (en) * | 2014-04-03 | 2014-07-30 | 思南县高山草原种养专业合作社 | Composition for treating bloat and grainsick |
| CN104162137A (en) * | 2014-08-21 | 2014-11-26 | 陈键 | Traditional Chinese medicine mixture for treating bovine forestomach atony and preparation method thereof |
| CN104222636A (en) * | 2014-09-15 | 2014-12-24 | 山东新希望六和集团有限公司 | Functional feed for preventing and treating cow rumen distension and preparation method of functional feed |
| CN104351479A (en) * | 2014-11-28 | 2015-02-18 | 张汉桥 | Feed additive for beef cattle as well as preparation method and using method thereof |
| CN104398635A (en) * | 2014-11-29 | 2015-03-11 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof |
| CN104522437A (en) * | 2015-02-04 | 2015-04-22 | 甘肃春寅乳业有限责任公司 | Health cattle feed for preventing ruminal impaction in early spring |
| CN104998265A (en) * | 2015-07-10 | 2015-10-28 | 陕西溯源农业发展有限公司 | Preparation method of compound Chinese herbal medicine for promoting rumination of ruminant and extract of compound Chinese herbal medicine |
| CN110652551A (en) * | 2019-09-29 | 2020-01-07 | 贵州慧创科技发展有限公司 | Traditional Chinese medicine preparation for treating forestomach diseases of cattle and sheep, and preparation method and application thereof |
| CN113750191A (en) * | 2021-10-12 | 2021-12-07 | 河北坤元饲料有限公司 | Chinese herbal medicine stomach-invigorating composition for ruminant feed and preparation method thereof |
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| CN105999145A (en) * | 2016-05-27 | 2016-10-12 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicinal oral liquid for treating bovine fore-stomach stony and preparation method of traditional Chinese medicinal oral liquid |
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| CN102599387A (en) * | 2012-03-23 | 2012-07-25 | 蒋勇 | Traditional Chinese medicine additive for fattening cattle and applications thereof |
| CN103948685A (en) * | 2014-04-03 | 2014-07-30 | 思南县高山草原种养专业合作社 | Composition for treating bloat and grainsick |
| CN103948685B (en) * | 2014-04-03 | 2016-08-17 | 思南县高山草原种养专业合作社 | A kind of composition treating bovine rumen distension gas |
| CN104162137A (en) * | 2014-08-21 | 2014-11-26 | 陈键 | Traditional Chinese medicine mixture for treating bovine forestomach atony and preparation method thereof |
| CN104222636A (en) * | 2014-09-15 | 2014-12-24 | 山东新希望六和集团有限公司 | Functional feed for preventing and treating cow rumen distension and preparation method of functional feed |
| CN104351479A (en) * | 2014-11-28 | 2015-02-18 | 张汉桥 | Feed additive for beef cattle as well as preparation method and using method thereof |
| CN104398635A (en) * | 2014-11-29 | 2015-03-11 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof |
| CN104522437A (en) * | 2015-02-04 | 2015-04-22 | 甘肃春寅乳业有限责任公司 | Health cattle feed for preventing ruminal impaction in early spring |
| CN104998265A (en) * | 2015-07-10 | 2015-10-28 | 陕西溯源农业发展有限公司 | Preparation method of compound Chinese herbal medicine for promoting rumination of ruminant and extract of compound Chinese herbal medicine |
| CN110652551A (en) * | 2019-09-29 | 2020-01-07 | 贵州慧创科技发展有限公司 | Traditional Chinese medicine preparation for treating forestomach diseases of cattle and sheep, and preparation method and application thereof |
| CN113750191A (en) * | 2021-10-12 | 2021-12-07 | 河北坤元饲料有限公司 | Chinese herbal medicine stomach-invigorating composition for ruminant feed and preparation method thereof |
| CN116370587A (en) * | 2023-03-16 | 2023-07-04 | 贵州黄牛产业集团科技服务有限公司 | Compound Chinese herbal medicine preparation special for treating cattle fore-stomach diseases and preparation method thereof |
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