CN104940872A - Traditional Chinese medicine composition for treating equine intestinal tympany and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating equine intestinal tympany and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating equine intestinal tympany. The traditional Chinese medicine composition is prepared from mangnolia officinalis, fresh ginger, pinellia ternate, liquorice, codonopsis pilosula, rheum officinale, mirabilite, radix ophiopogonis and medicated leaven. The traditional Chinese medicine composition can be powder and is prepared through the following steps: (1) weighing the crude drugs according to the formula ratio; (2) smashing the crude drugs, and sieving the smashed crude drugs with a 40-80-mesh sieve; (3) mixing the sieved crude drugs for 5-10 minutes to obtain traditional Chinese medicine powder; (4) subpackaging the traditional Chinese medicine powder in bags to obtain the finished product, wherein each bag contains 100-200 g of the traditional Chinese medicine powder. The traditional Chinese medicine composition has the efficacies of descending qi to remove fullness, removing food retention and removing food stagnation, warming stomach and stopping vomiting, tonifying spleen and qi, promoting appetite and helping digestion, can effectively treat equine intestinal tympany and has a curative rate of 96%.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind ofly treat Chinese medicine composition of horse intestinal distension gas and preparation method thereof.
Background technology
Intestinal distension gas is that intestinal contents aerogenesis is vigorous, and intestinal exhaust process freely or is not completely obstructed, and causes accumulated gases in certain part or most of intestinal tube because intestinal digestion is in disorder, causes the stomachache of intestinal tube tympanites sick.Horse intestinal distension gas mostly occurs in summer and autumn, main cause is once the excessive herbage (particularly the leguminous forage such as Herba Medicaginis) fed or herd fresh and tender succulence, these excessive forage grasses are after the intestines and stomach is obstructed stop, sharply gassy fermentation, a large amount of gas too much can not be discharged in time because of the intestines and stomach forage grass again, thus causes intestinal distension gas.This sick morbidity is rapid, morbidity in 2 ~ 4 hours after food usually.There is intermittent stomachache in the ill domestic animal initial stage, and transfers rapidly the violent and stomachache of persistence to, time the sleeping or rolling that falls down to the ground when rising, abdominal circumference increases very soon, and tympanitic resonance or metallic sound appear in percussion, the displacement of secondary intestinal, intussusception or enterorrhexis time serious and dead.The sick just rare soft feces of the many rows of ill domestic animal, then stops defecation afterwards completely.
Therapeutic Method many employings exhaust decompression in the past, analgesia spasmolytic and bowel relieving stop ferment triple combination and carry out.Exhaust decompression can take respective handling according to distension gas degree.The not serious person of intestinal distension gas, can apply cathartic, only ferment agent and remove intestinal contents, with consolidate curative effect.When domestic animal serious intestinal distension gas, abdominal circumference enlarges markedly, rapid breathing, during increased heart rate, should adopt immediately and wear intestinal blind enema, after aerofluxus, injects only ferment agent by venting syringe needle.For prevention secondary peritonitis, also must inject antibacterial-anti-inflammatory drug in abdominal cavity after venting, conventional has penicillin and Procaine injection.Conventional tranquillizing to relieve muscle spasm medicine has chloral hydrate, dipyrone, peace bromine injection etc.Method effect passing is as can be seen here single, and the multiple method conbined usage of normal needs, thus causes complex steps, complicated operation.And use antibiotic also to there is drug residue problem.Adopt treatment by Chinese herbs horse intestinal distension gas, carry out reasonable material and scientific compatibility, can reach the object that a medicine is controlled more according to disease, make treatment more simple, operation is easier, saves time and cost.And treatment by Chinese herbs horse intestinal distension gas drug residue free, safer.Therefore, the Chinese medicine preparation of exploitation treatment horse intestinal distension gas is an important research direction of this area.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of evident in efficacy, cure rate is high, side effect is low Chinese medicine composition.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula for the treatment of horse intestinal distension gas.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of horse intestinal distension gas, is characterized in that: be prepared from by the raw material of following mass fraction: Cortex Magnoliae Officinalis 15-30 part, Rhizoma Zingiberis Recens 7-12 part, Rhizoma Pinelliae 8-15 part, Radix Glycyrrhizae 6-9 part, Radix Codonopsis 10-15 part, Radix Et Rhizoma Rhei 6-10 part, Natrii Sulfas 6-10 part, Radix Ophiopogonis 6-12 part, Massa Medicata Fermentata 7-15 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: Cortex Magnoliae Officinalis 30 parts, 7 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 8 parts, 6 parts, Radix Glycyrrhizae, Radix Codonopsis 15 parts, Radix Et Rhizoma Rhei 9 parts, 7 parts, Natrii Sulfas, Radix Ophiopogonis 8 parts, Massa Medicata Fermentata 10 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) takes each Chinese medicine by formula ratio, and Chinese medicine is pulverized by (2), crosses 40-80 mesh sieve; (3) mix 5-10 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 100-200g subpackage, get product.
The advantage that the present invention has and good effect are:
(1) this prescription is according to tcm theory, and scientific compatibility, has effect of relieving distension dispelling the stagnated QI, wide intestinal relieving constipation, invigorating the spleen and replenishing QI.Through Clinical Laboratory determined curative effect, cure rate is up to 96%.
(2) Chinese medicine preparation obtained according to this prescription has that preparation is simple and easy, easy to use, rapid-action, side effect is low, the advantage of environmental protection, and mutually the therapeutic scheme of multiple method conbined usage than ever, more simple.
(3) pharmacology of each raw material of Chinese medicine of the present invention is:
Cortex Magnoliae Officinalis: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full;
Rhizoma Zingiberis Recens: warming middle-JIAO to arrest vomiting;
The Rhizoma Pinelliae: stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription;
Radix Codonopsis: invigorating the spleen and replenishing QI, and taste;
Radix Et Rhizoma Rhei: heat and toxic materials clearing away, controls stagnant constipation;
Natrii Sulfas: relieving constipation by purgation;
Radix Ophiopogonis: nourishing YIN and moistening the lung, reinforcing stomach reg fluid;
Massa Medicata Fermentata: help digestion stomach function regulating.
According to the viewpoint of the traditional Chinese medical science, horse intestinal distension gas is that tripe is swollen or depressed, and treatment based on relieving distension dispelling the stagnated QI and wide intestinal relieving constipation, should be aided with invigorating the spleen and replenishing QI, the medicine of the stomach function regulating that helps digestion simultaneously.Among formula, Cortex Magnoliae Officinalis is principal agent, and it is bitter dry pungent loose, energy dampness, and the therapeutic method to keep the adverse QI flowing downwards is except distension again, is the key medicine eliminating distension; This product also can therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, and consumer product dredge stasis, is equipped with the medicine of the relieving constipation by purgation such as Radix Et Rhizoma Rhei, Natrii Sulfas, to reach drastic purgation accumulation of heat, and the effect of consumer product dredge stasis.The pungent loose temperature of Rhizoma Zingiberis Recens is led to, energy warming spleen and stomach for dispelling cold, particularly suitable to deficiency of spleen-QI and stomach-QI person.Rhizoma Pinelliae bitter in the mouth normalizing the stomach by guiding QI downward, all effective to the vomiting of a variety of causes, compatibility Rhizoma Zingiberis Recens can control the adverse rising of stomach-QI vomiting caused by cold syndrome of the stomach.Radix Codonopsis nature and flavor are sweet flat, and master returns spleen lung two warp, and its Main Function is the gas of spleen reinforcing lung.Radix Glycyrrhizae sweet in the mouth, is apt to, into middle Jiao, also have the power of invigorating the spleen and replenishing QI, but its effect relaxes, as adjuvant drug.Simultaneously Radix Glycyrrhizae also has effect of relieving spasm to stop pain, also can be in harmonious proportion the property of medicine, the property that in reduction side, the poison of Radix Et Rhizoma Rhei is strong.Radix Ophiopogonis is longer than nourishing stomach-YIN, promoting the production of body fluid to quench thirst, and clearing away stomach-heat of holding concurrently, being widely used in deficiency of stomach-YIN has the dry tongue of heat thirsty, gastralgia, vomiting, the diseases such as constipation with dry stool.Radix Ophiopogonis and the Rhizoma Pinelliae, Radix Codonopsis are vomitted by the QI rising in reverse order can controlling deficiency of stomach-Yin together.Massa Medicata Fermentata is pungent to help digestion so that row is loose, and sweet temperature spleen benefiting and stimulating the appetite, can treat dyspepsia distension and fullness in the abdomen.Above-mentioned nine taste medicine compatibilities use, and have the therapeutic method to keep the adverse QI flowing downwards except full, consumer product dredge stasis, stomach warming preventing or arresting vomiting, invigorating the spleen and replenishing QI, appetite-stimulating indigestion-relieving effect.
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Treat a Chinese powder medicine for horse intestinal distension gas, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 30 parts, 7 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 8 parts, 6 parts, Radix Glycyrrhizae, Radix Codonopsis 15 parts, Radix Et Rhizoma Rhei 9 parts, 7 parts, Natrii Sulfas, Radix Ophiopogonis 8 parts, Massa Medicata Fermentata 10 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Embodiment 2
Treat a Chinese powder medicine for horse intestinal distension gas, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 15 parts, 8 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 13 parts, 9 parts, Radix Glycyrrhizae, Radix Codonopsis 10 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts, Natrii Sulfas, Radix Ophiopogonis 10 parts, Massa Medicata Fermentata 15 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Embodiment 3
Treat a Chinese powder medicine for horse intestinal distension gas, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 20 parts, 10 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 15 parts, 8 parts, Radix Glycyrrhizae, Radix Codonopsis 12 parts, Radix Et Rhizoma Rhei 8 parts, 8 parts, Natrii Sulfas, Radix Ophiopogonis 12 parts, Massa Medicata Fermentata part system 7 are for forming.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Embodiment 4
Treat a Chinese powder medicine for horse intestinal distension gas, the parts by weight of each raw material are as follows: Cortex Magnoliae Officinalis 25 parts, 12 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 12 parts, 7 parts, Radix Glycyrrhizae, Radix Codonopsis 14 parts, Radix Et Rhizoma Rhei 6 parts, 6 parts, Natrii Sulfas, Radix Ophiopogonis 6 parts, Massa Medicata Fermentata 12 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Clinical trial
Experiment 1:
After the horses usage of horse keeping family one, Jixian Tianjin, fed evening a large amount of Semen Maydis and Testa oryzae, these horses morbidity after about 2 hours.Show as unable to sleep soundly, later turned round and look at abdomen, forelimb has been planed the ground, rolled about.The visible abdominal circumference of clinical examination increases, and conjunctiva cyanosis, intestinal sound disappears substantially.Examination per rectum touches circular hard obturator on the horizontal line of pubis leading edge.According to the cause of disease and result of clinical detection, be diagnosed as microcolon constipation secondary intestinal distension gas.Give the product that ill domestic animal spice is fed obtained by embodiment 1 immediately, spice, than being 200g:150kg feedstuff, every day 2 times, is used in conjunction 3.After medication, second day horses just pulls out a large amount of spherical hard feces, and stomachache disappears, and abdominal circumference obviously reduces.Continue use after 2 days, horses abdomen tympanites transference cure, abdominal circumference recovers normal, and defecation and diet all recover normal.
Test 1 result and show that the Chinese powder medicine treatment horse intestinal distension gas of use obtained by the embodiment of the present invention 1 is rapid-action, evident in efficacy, be adapted at doing further genralrlization clinically.
Experiment 2
The a group Mongolian horse that stud-farm, Baotou is raised, on the occasion of It is the end of summer, just turning into autumn, in the sky cyclostrophic cool time, has eaten fresh Herba Medicaginis in a large number when herding.Within about 2 hours, start have horses to fall ill successively after edible, Symptoms is ill domestic animal stomachache, initial stage is intermittent stomachache, and transfer rapidly the acutely stomachache of persistence to, sleeping or the rolling that falls down to the ground when time rises, abdominal part expands rapidly even projection, guarding, there is tympanitic resonance or metallic sound in percussion, full group about has 90% morbidity.According to pathogenic factor and clinical symptoms, be diagnosed as horse intestinal distension gas.Give the product obtained by the ill domestic animal embodiment of the present invention 1 immediately, the spice ratio of feeding is 200g:150kg feedstuff, 2 times on the one, uses 3 continuously.Feed after 2 times, namely most of horses discharge a large amount of feces and gas, and abdominal circumference obviously reduces, and pain disappears.After continuing to feed 2, apart from two ill domestic animals because of outside the state of an illness too Serious Mortality, jumpbogroup recovers normal, and abdominal circumference and feed all recover normal, and cure rate is up to 96%.
Test 2 results to show, the product obtained by the embodiment of the present invention 1 is used for the treatment of horse intestinal distension gas determined curative effect, and clinical effective rate can up to 96%.And therapeutic scheme is simple, especially applicable for large-scale ranch.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (5)
1. treat a Chinese medicine composition for horse intestinal distension gas, it is characterized in that, be prepared from by the raw material of following mass fraction:
Cortex Magnoliae Officinalis 15-30 part, Rhizoma Zingiberis Recens 7-12 part, Rhizoma Pinelliae 8-15 part, Radix Glycyrrhizae 6-9 part, Radix Codonopsis 10-15 part, Radix Et Rhizoma Rhei 6-10 part, Natrii Sulfas 6-10 part, Radix Ophiopogonis 6-12 part, Massa Medicata Fermentata 7-15 part.
2. the Chinese medicine composition for the treatment of horse intestinal distension gas according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Cortex Magnoliae Officinalis 30 parts, 7 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 8 parts, 6 parts, Radix Glycyrrhizae, Radix Codonopsis 15 parts, Radix Et Rhizoma Rhei 9 parts, 7 parts, Natrii Sulfas, Radix Ophiopogonis 8 parts, Massa Medicata Fermentata 10 parts.
3. the Chinese medicine composition for the treatment of horse intestinal distension gas according to claim 1 and 2, is characterized in that: this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
4. the Chinese medicine composition for the treatment of horse intestinal distension gas according to claim 3, is characterized in that: described preparation can be powder.
5. prepare a method for the Chinese medicine composition for the treatment of horse intestinal distension gas as claimed in claim 4, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 40-80 mesh sieve; (3) mix 5-10 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 100-200g subpackage, get product.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784706A (en) * | 2013-12-14 | 2014-05-14 | 青岛德瑞骏发生物科技有限公司 | Medicine composition for treating intestinal tympany of equus animals |
| CN104398635A (en) * | 2014-11-29 | 2015-03-11 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784706A (en) * | 2013-12-14 | 2014-05-14 | 青岛德瑞骏发生物科技有限公司 | Medicine composition for treating intestinal tympany of equus animals |
| CN104398635A (en) * | 2014-11-29 | 2015-03-11 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicinal composition for treating acute ruminal tympany of sheep and preparation method thereof |
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Application publication date: 20150930 |