CN104374926B - 利用NT‑proET‑1的诊断和风险分层 - Google Patents
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/5754—Endothelin, vasoactive intestinal contractor [VIC]
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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| US8906857B2 (en) * | 2005-12-01 | 2014-12-09 | B.R.A.H.M.S. Gmbh | Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists |
| EP2472258A3 (en) | 2006-04-04 | 2012-11-28 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| DE102006046996A1 (de) * | 2006-10-01 | 2008-04-03 | Brahms Aktiengesellschaft | Diagnose von Infektionen oder Entzündungserkrankungen der Atemwege und Lunge assoziiert mit Herzinsuffizienz |
| JP5320294B2 (ja) * | 2006-10-26 | 2013-10-23 | ベー．エル．アー．ハー．エム．エス ゲーエムベーハー | プロバソプレシンまたはその断片および部分ペプチド、特にコペプチンまたはニューロフィジンｉｉを使用する、急性冠動脈症候群についてのリスク層化 |
| DE102006053442A1 (de) * | 2006-11-12 | 2008-05-15 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Infektionen und chronischen Erkrankungen der Atemwege und Lunge mittels proVasopressin, insbesondere Copeptin oder Neurophysin II |
| DE102006060112A1 (de) | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| DE102007021443A1 (de) * | 2007-05-08 | 2008-11-13 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels NT-proET-1 |
| US9229013B2 (en) * | 2009-05-05 | 2016-01-05 | B.R.A.H.M.S Gmbh | Vasoactive hormone-based stratification of patients suffering from diseases related to endothelial function/dysfunction |
| AU2010259022B2 (en) | 2009-06-08 | 2016-05-12 | Singulex, Inc. | Highly sensitive biomarker panels |
| WO2012059477A1 (en) * | 2010-11-01 | 2012-05-10 | B.R.A.H.M.S Gmbh | Prognosis and risk assessment of patients with non-specific complaints |
| EP2637023A1 (en) * | 2012-03-08 | 2013-09-11 | B.R.A.H.M.S GmbH | Prediction of outcome in patients with chronic obstructive pulmonary disease |
| KR101531835B1 (ko) * | 2013-10-16 | 2015-06-29 | 한국표준과학연구원 | 화학적 동위원소 치환법을 이용한 혈액 내 뇌성 나트륨 이뇨 펩타이드 질량분석법 |
| CN106370856B (zh) * | 2016-08-16 | 2019-04-02 | 北京师范大学 | 肺纤维化的尿液蛋白标志物及其在诊断和预后中的用途 |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
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| JP3519139B2 (ja) * | 1993-10-19 | 2004-04-12 | 武田薬品工業株式会社 | エンドセリン拮抗阻害剤スクリーニング用キット及びスクリーニング方法 |
| DE19847690A1 (de) * | 1998-10-15 | 2000-04-20 | Brahms Diagnostica Gmbh | Verfahren und Substanzen für die Diagnose und Therapie von Sepsis und sepsisähnlichen systemischen Infektionen |
| KR20020068262A (ko) * | 1999-03-05 | 2002-08-27 | 에피제네시스 파마슈티칼스 아이엔씨 | 타겟 및 경로 유효/무효화 방법 |
| AUPR005600A0 (en) * | 2000-09-12 | 2000-10-05 | University Of Sydney, The | Diagnostic assay |
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| US20050244839A1 (en) * | 2004-04-29 | 2005-11-03 | Cheung Siu T | Granulin-epithelin precursor (GEP) overexpression as a target for diagnosis, prognosis and treatment of hepatocellular carcinoma (HCC) |
| EP1619505B1 (en) * | 2004-07-22 | 2008-04-16 | BRAHMS Aktiengesellschaft | Method for the diagnosis of critically ill patients |
| DE102004051847B4 (de) * | 2004-10-25 | 2008-09-18 | Dade Behring Marburg Gmbh | Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen |
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2007
- 2007-05-08 DE DE102007021443A patent/DE102007021443A1/de not_active Withdrawn
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2008
- 2008-05-08 JP JP2010506800A patent/JP5717442B2/ja active Active
- 2008-05-08 EP EP10191423A patent/EP2306203B1/de active Active
- 2008-05-08 WO PCT/DE2008/000781 patent/WO2008135038A2/de not_active Ceased
- 2008-05-08 EP EP08758039.5A patent/EP2147316B1/de active Active
- 2008-05-08 CN CN200880018171.XA patent/CN101688869B/zh not_active Expired - Fee Related
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2388055T3 (es) | 2012-10-08 |
| CN101688869B (zh) | 2014-09-17 |
| HK1203089A1 (en) | 2015-10-16 |
| US20110039283A1 (en) | 2011-02-17 |
| CN101688869A (zh) | 2010-03-31 |
| HK1139733A1 (en) | 2010-09-24 |
| EP2147316B1 (de) | 2013-07-10 |
| JP5932924B2 (ja) | 2016-06-08 |
| WO2008135038A3 (de) | 2009-02-05 |
| JP2015007653A (ja) | 2015-01-15 |
| EP2306203A1 (de) | 2011-04-06 |
| JP2010526305A (ja) | 2010-07-29 |
| JP5717442B2 (ja) | 2015-05-13 |
| EP2306203B1 (de) | 2012-07-11 |
| EP2147316A2 (de) | 2010-01-27 |
| US9261516B2 (en) | 2016-02-16 |
| US20160161505A1 (en) | 2016-06-09 |
| WO2008135038A2 (de) | 2008-11-13 |
| DE102007021443A1 (de) | 2008-11-13 |
| CN104374926A (zh) | 2015-02-25 |
| ES2430218T3 (es) | 2013-11-19 |
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