ES2388055T3 - Diagnóstico y estratificación de riesgo mediante NT-proET-1 - Google Patents

Diagnóstico y estratificación de riesgo mediante NT-proET-1 Download PDF

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Publication number
ES2388055T3
ES2388055T3 ES10191423T ES10191423T ES2388055T3 ES 2388055 T3 ES2388055 T3 ES 2388055T3 ES 10191423 T ES10191423 T ES 10191423T ES 10191423 T ES10191423 T ES 10191423T ES 2388055 T3 ES2388055 T3 ES 2388055T3
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Spain
Prior art keywords
diagnosis
diseases
respiratory tract
seq
risk stratification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10191423T
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English (en)
Spanish (es)
Inventor
Andreas Bergmann
Joachim Struck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRAHMS GmbH
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BRAHMS GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of ES2388055T3 publication Critical patent/ES2388055T3/es
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/5754Endothelin, vasoactive intestinal contractor [VIC]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • G01N2800/122Chronic or obstructive airway disorders, e.g. asthma COPD
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/324Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
ES10191423T 2007-05-08 2008-05-08 Diagnóstico y estratificación de riesgo mediante NT-proET-1 Active ES2388055T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007021443 2007-05-08
DE102007021443A DE102007021443A1 (de) 2007-05-08 2007-05-08 Diagnose und Risikostratifizierung mittels NT-proET-1

Publications (1)

Publication Number Publication Date
ES2388055T3 true ES2388055T3 (es) 2012-10-08

Family

ID=39745333

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10191423T Active ES2388055T3 (es) 2007-05-08 2008-05-08 Diagnóstico y estratificación de riesgo mediante NT-proET-1
ES08758039T Active ES2430218T3 (es) 2007-05-08 2008-05-08 Diagnóstico y estratificación de riesgo mediante NT-proET-1

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES08758039T Active ES2430218T3 (es) 2007-05-08 2008-05-08 Diagnóstico y estratificación de riesgo mediante NT-proET-1

Country Status (7)

Country Link
US (2) US9261516B2 (enExample)
EP (2) EP2306203B1 (enExample)
JP (2) JP5717442B2 (enExample)
CN (2) CN101688869B (enExample)
DE (1) DE102007021443A1 (enExample)
ES (2) ES2388055T3 (enExample)
WO (1) WO2008135038A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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US8906857B2 (en) * 2005-12-01 2014-12-09 B.R.A.H.M.S. Gmbh Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists
EP2472258A3 (en) 2006-04-04 2012-11-28 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
DE102006046996A1 (de) * 2006-10-01 2008-04-03 Brahms Aktiengesellschaft Diagnose von Infektionen oder Entzündungserkrankungen der Atemwege und Lunge assoziiert mit Herzinsuffizienz
JP5320294B2 (ja) * 2006-10-26 2013-10-23 ベー.エル.アー.ハー.エム.エス ゲーエムベーハー プロバソプレシンまたはその断片および部分ペプチド、特にコペプチンまたはニューロフィジンiiを使用する、急性冠動脈症候群についてのリスク層化
DE102006053442A1 (de) * 2006-11-12 2008-05-15 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung von Infektionen und chronischen Erkrankungen der Atemwege und Lunge mittels proVasopressin, insbesondere Copeptin oder Neurophysin II
DE102006060112A1 (de) 2006-12-20 2008-06-26 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM
DE102007021443A1 (de) * 2007-05-08 2008-11-13 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung mittels NT-proET-1
US9229013B2 (en) * 2009-05-05 2016-01-05 B.R.A.H.M.S Gmbh Vasoactive hormone-based stratification of patients suffering from diseases related to endothelial function/dysfunction
AU2010259022B2 (en) 2009-06-08 2016-05-12 Singulex, Inc. Highly sensitive biomarker panels
WO2012059477A1 (en) * 2010-11-01 2012-05-10 B.R.A.H.M.S Gmbh Prognosis and risk assessment of patients with non-specific complaints
EP2637023A1 (en) * 2012-03-08 2013-09-11 B.R.A.H.M.S GmbH Prediction of outcome in patients with chronic obstructive pulmonary disease
KR101531835B1 (ko) * 2013-10-16 2015-06-29 한국표준과학연구원 화학적 동위원소 치환법을 이용한 혈액 내 뇌성 나트륨 이뇨 펩타이드 질량분석법
CN106370856B (zh) * 2016-08-16 2019-04-02 北京师范大学 肺纤维化的尿液蛋白标志物及其在诊断和预后中的用途
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US12322100B2 (en) 2018-12-11 2025-06-03 Eko.Ai Pte. Ltd. Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity
US12400762B2 (en) 2018-12-11 2025-08-26 Eko.Ai Pte. Ltd. Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3519139B2 (ja) * 1993-10-19 2004-04-12 武田薬品工業株式会社 エンドセリン拮抗阻害剤スクリーニング用キット及びスクリーニング方法
DE19847690A1 (de) * 1998-10-15 2000-04-20 Brahms Diagnostica Gmbh Verfahren und Substanzen für die Diagnose und Therapie von Sepsis und sepsisähnlichen systemischen Infektionen
KR20020068262A (ko) * 1999-03-05 2002-08-27 에피제네시스 파마슈티칼스 아이엔씨 타겟 및 경로 유효/무효화 방법
AUPR005600A0 (en) * 2000-09-12 2000-10-05 University Of Sydney, The Diagnostic assay
US7713705B2 (en) * 2002-12-24 2010-05-11 Biosite, Inc. Markers for differential diagnosis and methods of use thereof
EP2386863A1 (en) * 2002-10-09 2011-11-16 DMI Biosciences, Inc. Diagnosis and monitoring of multiple organ failure
JP2007503393A (ja) * 2003-08-22 2007-02-22 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド Copd及び肺高血圧の治療方法
EP1564558B1 (de) 2004-02-13 2005-12-07 B.R.A.H.M.S Aktiengesellschaft Verfahren zur Bestimmung der Bildung von Endothelinen zu Zwecken der medizinischen Diagnostik, sowie Antikörper und Kits für die Durchführung eines solchen Verfahrens
US20050244839A1 (en) * 2004-04-29 2005-11-03 Cheung Siu T Granulin-epithelin precursor (GEP) overexpression as a target for diagnosis, prognosis and treatment of hepatocellular carcinoma (HCC)
EP1619505B1 (en) * 2004-07-22 2008-04-16 BRAHMS Aktiengesellschaft Method for the diagnosis of critically ill patients
DE102004051847B4 (de) * 2004-10-25 2008-09-18 Dade Behring Marburg Gmbh Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen
CA2596986A1 (en) * 2005-02-14 2006-08-24 Wyeth Use of il-17f in diagnosis and therapy of airway inflammation
JP2006292623A (ja) * 2005-04-13 2006-10-26 Univ Of Dundee 心不全における突然死のマーカー
UA11822U (en) * 2005-06-21 2006-01-16 L T Malaia Inst Of Therapy Of Method for determining the risk of the development and progressing of chronic obstructive pulmonary disease
WO2007013041A2 (en) * 2005-07-29 2007-02-01 Koninklijke Philips Electronics, N.V. Monitoring of cardiac natriuretic peptides during diagnosis, managment, and treatment of cardiac diseases
DE102006046996A1 (de) * 2006-10-01 2008-04-03 Brahms Aktiengesellschaft Diagnose von Infektionen oder Entzündungserkrankungen der Atemwege und Lunge assoziiert mit Herzinsuffizienz
DE102006060835A1 (de) * 2006-12-22 2008-06-26 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung des akuten Koronarsyndroms mittels CT-proET-1 in Kombination mit NT-proBNP
DE102007021443A1 (de) * 2007-05-08 2008-11-13 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung mittels NT-proET-1

Also Published As

Publication number Publication date
CN101688869B (zh) 2014-09-17
HK1203089A1 (en) 2015-10-16
US20110039283A1 (en) 2011-02-17
CN101688869A (zh) 2010-03-31
HK1139733A1 (en) 2010-09-24
EP2147316B1 (de) 2013-07-10
JP5932924B2 (ja) 2016-06-08
WO2008135038A3 (de) 2009-02-05
JP2015007653A (ja) 2015-01-15
EP2306203A1 (de) 2011-04-06
JP2010526305A (ja) 2010-07-29
JP5717442B2 (ja) 2015-05-13
EP2306203B1 (de) 2012-07-11
EP2147316A2 (de) 2010-01-27
US9261516B2 (en) 2016-02-16
US20160161505A1 (en) 2016-06-09
WO2008135038A2 (de) 2008-11-13
DE102007021443A1 (de) 2008-11-13
CN104374926B (zh) 2017-05-17
CN104374926A (zh) 2015-02-25
ES2430218T3 (es) 2013-11-19

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