CN104366485A - 一种增强免疫力的片剂及其制备方法 - Google Patents
一种增强免疫力的片剂及其制备方法 Download PDFInfo
- Publication number
- CN104366485A CN104366485A CN201410732012.3A CN201410732012A CN104366485A CN 104366485 A CN104366485 A CN 104366485A CN 201410732012 A CN201410732012 A CN 201410732012A CN 104366485 A CN104366485 A CN 104366485A
- Authority
- CN
- China
- Prior art keywords
- parts
- tablet
- weight
- extracts
- maltodextrin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 6
- 230000036039 immunity Effects 0.000 title abstract description 16
- 238000000034 method Methods 0.000 title abstract description 8
- 230000002708 enhancing effect Effects 0.000 title abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 28
- 230000000694 effects Effects 0.000 claims abstract description 18
- 240000001080 Grifola frondosa Species 0.000 claims abstract description 14
- 235000007710 Grifola frondosa Nutrition 0.000 claims abstract description 14
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 13
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 13
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 13
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 13
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 13
- 239000008187 granular material Substances 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 241000168525 Haematococcus Species 0.000 claims description 13
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 12
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 12
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 12
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 12
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims description 10
- 238000002360 preparation method Methods 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 6
- 238000005469 granulation Methods 0.000 claims description 3
- 230000003179 granulation Effects 0.000 claims description 3
- 235000020985 whole grains Nutrition 0.000 claims description 3
- 230000032683 aging Effects 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 241001493577 Haematococcaceae Species 0.000 abstract 1
- 240000008866 Ziziphus nummularia Species 0.000 abstract 1
- 238000010923 batch production Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000007493 shaping process Methods 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 241000700605 Viruses Species 0.000 description 6
- 230000036541 health Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 208000033065 inborn errors of immunity Diseases 0.000 description 4
- 208000028529 primary immunodeficiency disease Diseases 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000000987 immune system Anatomy 0.000 description 3
- 230000009545 invasion Effects 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 241000606161 Chlamydia Species 0.000 description 1
- 241000709661 Enterovirus Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000003464 asthenopia Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 235000021179 potluck Nutrition 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 208000020685 sleep-wake disease Diseases 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/37—Sugar alcohols
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
一种增强免疫力的片剂及其制备方法，由原料按以下重量份数制成，灰树花提取物10-15份、大枣提取物10-15份、红球藻5-10份、山梨糖醇30-45份、麦芽糊精3-5份、微晶纤维素20-30份、硬脂酸镁0.5-1份；其制备方法的主要步骤为：步骤1、混合；步骤2、制粒；步骤3、烘干；步骤4、整粒；步骤5、压片。本发明的一种增强免疫力的片剂， 具有 增强免疫力、抗氧化、抗老化的作用，并且其工艺简单，适合大批量生产。
Description
技术领域
本发明属于保健食品领域，具体涉及一种增强免疫力的片剂及其制备方法。
背景技术
免疫力是人体自身的防御机制，是人体识别和消灭外来侵入的任何异物（病毒、细菌等）；处理衰老、损伤、死亡、变性的自身细胞以及识别和处理体内突变细胞和病毒感染细胞的能力。现代免疫学认为，免疫力是人体识别和排除“异己”的生理反应。人体内执行这一功能的是免疫系统，可通过多种方法增强免疫力，饮食调理，多食用有益食品，特别是小孩、老人，需多注意免疫力的增强。
免疫力是指机体抵抗外来侵袭，维护体内环境稳定性的能力。空气中充满了各种各样的微生物：细菌、病毒、支原体、衣原体、真菌等等。在人体免疫力不足的情况下，它们都可以成为赶早班的病原体。虽然人体对不同的病原体会产生相应的抗体，以抵御再次感染，但抗体具有专一性和时限性，比如链球菌抗体只能在较短时期内保护机体不受链球菌的再次侵犯，也并不能抵御其他病毒的感染。免疫力低下的人根本无法抵御感冒病毒的侵袭，这才是他频繁感冒的真正原因。
现代医学科学发现，免疫是一个与衰老有密切关系的因素，免疫功能减退是衰老的最重要原因之一。机体免疫系统的一些特殊细胞能将入侵体内的细菌、病毒和体内已衰老死亡的细胞、已突变的细胞以及引起变态反应的物质，统统地加以吞噬和消灭，从而维持体内环境的稳定，保持机体健康。但机体免疫功能在30岁左右就开始减迟，这种变化是悄然、缓慢、持续地进行。
免疫力低下的表现:
免疫力低下的身体易于被感染或患癌症；免疫力超常也会产生对身体有害的结果如何提高孩子的免疫力，如引发过敏反应、自身免疫疾病等。
各种原因使免疫系统不能正常发挥保护作用，在此情况下，极易招致细菌、病毒、真菌等感染，因此免疫力低下最直接的表现就是容易生病。因经常患病，加重了机体的消耗，所以一般有体质虚弱、营养不良、精神萎靡、疲乏无力、食欲降低、睡眠障碍等表现，生病、打针吃药便成了家常便饭。每次生病都要很长时间才能恢复，而且常常反复发作。长此以往会导致身体和智力发育不良，还易诱发重大疾病。
越来越多的研究显示抗氧化是预防衰老的重要步骤，因为自由基或氧化剂会将细胞和组织分解，影响代谢功能，并会引起不同的健康问题。如果能够消除过多的氧化自由基，对于许多自由基引起的及老化相关疾病都能够预防。例如常见的癌症、动脉硬化、糖尿病、白内障、心血管病、老年痴呆、关节炎等，这些疾病都被认为与自由基相关。
目前市场上由许多增强免疫力的药物或是保健品，但是大多数药物的效果并不是很好，并且带有副作用，威胁人体健康，因此，为了人们更健康的生活，市场上急需一种既能提高自身对抗或者预防疾病的能力，也能放慢衰老的脚步的保健食品，同时食用方便、物美价廉。
发明内容
本发明的目的是提供一种具有增强免疫力、抗氧化、抗老化的片剂及其制备方法。
本发明的目的通过以下技术方案来实现：一种增强免疫力的片剂及其制备方法，由原料按以下重量份数制成，灰树花提取物10-15份、大枣提取物10-15份、红球藻5-10份、山梨糖醇30-45份、麦芽糊精3-5份、微晶纤维素20-30份、硬脂酸镁0.5-1份。
所述的一种增强免疫力的片剂，原料按优选重量份数，香菇提取物10份、灰树花提取物10份、大枣提取物10份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
所述的一种增强免疫力的片剂，原料按优选重量份数，香菇提取物15份、灰树花提取物10份、大枣提取物15份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
所述的一种增强免疫力的片剂及其制备方法，其制备方法的主要步骤为：
步骤1、混合：按重量份数，取香菇提取物、灰树花提取物、大枣提取物、红球藻、山梨糖醇、麦芽糊精、微晶纤维素、硬脂酸镁，分别过70-90目筛，混合均匀；
步骤2、制粒：在步骤（1）的混合物中加入质量分数75%的乙醇溶液，乙醇溶液的质量是所有小颗粒质量的10%，过16目筛网，制得小颗粒；
步骤3、烘干：将步骤（2）的小颗粒在65℃下烘干240min，干燥至水分≤5%；
步骤4、整粒：将步骤（3）得到干燥至水分≤5%的颗粒，过14目筛网；
步骤5、压片：将步骤（4）过筛后的干燥颗粒按生产操作规程，用旋转式压片机压片，调节片重：每片0.5g，每5-10分钟检测一次片重，按10片计，重量差异控制范围4-5g/10片，调节压轮至片剂有适宜的硬度。
本发明的有益效果：本发明的一种增强免疫力的片剂由香菇提取物、灰树花提取物、大枣提取物、红球藻组成，具有增强免疫力、抗氧化、抗老化的作用，并且其工艺简单，适合大批量生产。
本发明经两组临床验证，其中一组为治疗组服用本发明，每天服用本发明一次，7天为一个疗程，另一组对照组使用抗衰老胶囊，每天使用一次，7天为一个疗程，每组选择门诊病人110例，其中男40例，女70例，最大年龄75岁，最小年龄35岁，临床表现为神经衰弱、疲乏、嗜睡、失眠、易激动、视力疲劳、免疫力下降，表一为服用一个疗程后的对照数据：
表1服用前后两组疗程比较(单位:人)
治疗组和对照组有显著差异，从而可以看出本发明在临床上的应用有显著的疗效。
具体实施方式
实施例1
一种增强免疫力的片剂，由原料按以下重量份数制成，灰树花提取物10-15份、大枣提取物10-15份、红球藻5-10份、山梨糖醇30-45份、麦芽糊精3-5份、微晶纤维素20-30份、硬脂酸镁0.5-1份。
实施例2
一种增强免疫力的片剂，原料按优选重量份数，香菇提取物10份、灰树花提取物10份、大枣提取物10份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
实施例3
一种增强免疫力的片剂，原料按优选重量份数，香菇提取物15份、灰树花提取物10份、大枣提取物15份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
实施例4
一种增强免疫力的片剂及其制备方法，其制备方法的主要步骤为：
步骤1、混合：按重量份数，取香菇提取物、灰树花提取物、大枣提取物、红球藻、山梨糖醇、麦芽糊精、微晶纤维素、硬脂酸镁，分别过70-90目筛，混合均匀；
步骤2、制粒：在步骤（1）的混合物中加入质量分数75%的乙醇溶液，乙醇溶液的质量是所有小颗粒质量的10%，过16目筛网，制得小颗粒；
步骤3、烘干：将步骤（2）的小颗粒在65℃下烘干240min，干燥至水分≤5%；
步骤4、整粒：将步骤（3）得到干燥至水分≤5%的颗粒，过14目筛网；
步骤5、压片：将步骤（4）过筛后的干燥颗粒按生产操作规程，用旋转式压片机压片，调节片重：每片0.5g，每5-10分钟检测一次片重，按10片计，重量差异控制范围4-5g/10片，调节压轮至片剂有适宜的硬度。
Claims (4)
1.一种增强免疫力的片剂，其特征在于：由原料按以下重量份数制成，灰树花提取物10-15份、大枣提取物10-15份、红球藻5-10份、山梨糖醇30-45份、麦芽糊精3-5份、微晶纤维素20-30份、硬脂酸镁0.5-1份。
2.根据权利要求1所述的一种增强免疫力的片剂，其特征在于：原料按优选重量份数，香菇提取物10份、灰树花提取物10份、大枣提取物10份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
3.根据权利要求1所述的一种增强免疫力的片剂，其特征在于：原料按优选重量份数，香菇提取物15份、灰树花提取物10份、大枣提取物15份、红球藻10份、山梨糖醇40份、麦芽糊精5份、微晶纤维素15份、硬脂酸镁0.5-1份。
4.根据权利要求1-4所述的一种增强免疫力的片剂及其制备方法，其特征在于：其制备方法的主要步骤为：
步骤1、混合：按重量份数，取香菇提取物、灰树花提取物、大枣提取物、红球藻、山梨糖醇、麦芽糊精、微晶纤维素、硬脂酸镁，分别过70-90目筛，混合均匀；
步骤2、制粒：在步骤（1）的混合物中加入质量分数75%的乙醇溶液，乙醇溶液的质量是所有小颗粒质量的10%，过16目筛网，制得小颗粒；
步骤3、烘干：将步骤（2）的小颗粒在65℃下烘干240min，干燥至水分≤5%；
步骤4、整粒：将步骤（3）得到干燥至水分≤5%的颗粒，过14目筛网；
步骤5、压片：将步骤（4）过筛后的干燥颗粒按生产操作规程，用旋转式压片机压片，调节片重：每片0.5g，每5-10分钟检测一次片重，按10片计，重量差异控制范围4-5g/10片，调节压轮至片剂有适宜的硬度。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410732012.3A CN104366485A (zh) | 2014-12-06 | 2014-12-06 | 一种增强免疫力的片剂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410732012.3A CN104366485A (zh) | 2014-12-06 | 2014-12-06 | 一种增强免疫力的片剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104366485A true CN104366485A (zh) | 2015-02-25 |
Family
ID=52545876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410732012.3A Pending CN104366485A (zh) | 2014-12-06 | 2014-12-06 | 一种增强免疫力的片剂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104366485A (zh) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667135A (zh) * | 2015-03-19 | 2015-06-03 | 海南大学 | 一种药物组合物、保健品及制备方法 |
| CN105248801A (zh) * | 2015-09-02 | 2016-01-20 | 庆元大山合菌物科技有限公司 | 灰树花硬质糖及其制备方法 |
| CN109222061A (zh) * | 2018-09-25 | 2019-01-18 | 临沂信邦生物科技有限公司 | 蝙蝠蛾被毛孢食用菌片及制备方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101890056A (zh) * | 2010-08-05 | 2010-11-24 | 郭景龙 | 一种增强免疫功能的药物组合物 |
| CN101904873A (zh) * | 2010-08-05 | 2010-12-08 | 郭景龙 | 一种雨生红球藻为原料的药物 |
| CN102000129A (zh) * | 2010-11-16 | 2011-04-06 | 郭景龙 | 一种具有增强免疫力作用的药物组合物 |
| CN102634490A (zh) * | 2012-04-19 | 2012-08-15 | 深圳市中科海外科技有限公司 | 活菌酵素的制备工艺 |
| CN103431401A (zh) * | 2013-09-16 | 2013-12-11 | 厦门中药厂有限公司 | 一种抗氧化保健食品及其应用 |
-
2014
- 2014-12-06 CN CN201410732012.3A patent/CN104366485A/zh active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101890056A (zh) * | 2010-08-05 | 2010-11-24 | 郭景龙 | 一种增强免疫功能的药物组合物 |
| CN101904873A (zh) * | 2010-08-05 | 2010-12-08 | 郭景龙 | 一种雨生红球藻为原料的药物 |
| CN102000129A (zh) * | 2010-11-16 | 2011-04-06 | 郭景龙 | 一种具有增强免疫力作用的药物组合物 |
| CN102634490A (zh) * | 2012-04-19 | 2012-08-15 | 深圳市中科海外科技有限公司 | 活菌酵素的制备工艺 |
| CN103431401A (zh) * | 2013-09-16 | 2013-12-11 | 厦门中药厂有限公司 | 一种抗氧化保健食品及其应用 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667135A (zh) * | 2015-03-19 | 2015-06-03 | 海南大学 | 一种药物组合物、保健品及制备方法 |
| CN104667135B (zh) * | 2015-03-19 | 2017-11-10 | 海南大学 | 一种药物组合物、保健品及制备方法 |
| CN105248801A (zh) * | 2015-09-02 | 2016-01-20 | 庆元大山合菌物科技有限公司 | 灰树花硬质糖及其制备方法 |
| CN109222061A (zh) * | 2018-09-25 | 2019-01-18 | 临沂信邦生物科技有限公司 | 蝙蝠蛾被毛孢食用菌片及制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104366485A (zh) | 一种增强免疫力的片剂及其制备方法 | |
| CN104026446A (zh) | 一种适合于高血糖人群服用的营养代餐粉及其制备方法 | |
| CN103992416B (zh) | 金蝉花多糖及其在制备神经保护和抗衰老药物中的应用 | |
| CN104432060B (zh) | 一种高锌低钠维生素c泡腾片及其制备方法 | |
| CN103083270B (zh) | 一种叶黄素咀嚼片 | |
| CN108095122A (zh) | 叶黄素酯蓝莓红球藻片及其制备方法 | |
| CN103893393A (zh) | 一种具有抗氧化和增强免疫力的组合物及其制备方法 | |
| CN103169737B (zh) | 樟芝子实体与破壁灵芝孢子粉的组合物及其在免疫调节中的应用 | |
| Guo et al. | Vanadium-enriched Cordyceps sinensis, a contemporary treatment approach to both diabetes and depression in rats | |
| CN108065286A (zh) | 一种含有针叶樱桃粉、vc和牛磺酸的咀嚼片及其制备方法 | |
| Lu et al. | Regulatory effect of intracellular polysaccharides from Antrodia cinnamomea on the intestinal microbiota of mice with antibiotic-associated diarrhea | |
| CN102429150A (zh) | 一种增强人体免疫力的维生素c咀嚼片 | |
| CN103330211B (zh) | 一种具有免疫调节功能的组合物及其制备方法与应用 | |
| CN105707386A (zh) | 一种预防高血压的牛蒡复合压片糖果及其制备方法 | |
| CN110574913A (zh) | 一种富硒食用菌含食片及其制备方法 | |
| CN104382961A (zh) | 一种增加免疫力的艾克胶囊及其制备方法 | |
| Gangzheng et al. | Effect and correlation of Cordyceps guangdongensis ethanolic extract on obesity, dyslipidemia and gut microbiota dysbiosis in high-fat diet mice | |
| Chunchao et al. | A hypothesis: Supplementation with mushroom-derived active compound modulates immunity and increases survival in response to influenza virus (H1N1) infection | |
| Meng et al. | Immunomodulatory effects of Blaps rynchopetera extract | |
| CN108210745A (zh) | 一种具有免疫调节的辅助降血糖复方软胶囊及其制备方法 | |
| CN102860509A (zh) | 一种具有提高免疫力、抗疲劳作用的保健食品及其制备方法 | |
| WO2016169489A1 (zh) | 连翘苷、连翘苷衍生物、连翘苷与连翘脂素组合物在制备预防或/和治疗肝损伤药物或保健品中的应用 | |
| CN105707611A (zh) | 一种黑木耳复合固体饮料及其制备方法 | |
| CN103564476A (zh) | 一种增强机体免疫力的功能性食品 | |
| CN107582865A (zh) | 一种具有缓解疲劳、增强免疫力功效的药物组合物及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150225 |