CN104322499A - Compound bactericide - Google Patents
Compound bactericide Download PDFInfo
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- CN104322499A CN104322499A CN201410579055.2A CN201410579055A CN104322499A CN 104322499 A CN104322499 A CN 104322499A CN 201410579055 A CN201410579055 A CN 201410579055A CN 104322499 A CN104322499 A CN 104322499A
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- boscalid
- chlorobenzene ether
- acid amides
- bactericide
- ether acid
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Abstract
The invention belongs to the technical field of pesticides, and relates to a compound bactericide. The bactericide is characterized in that active components include chlorobenzene ether amide and cyprosulfamide. The composition can be prepared as a suspending agent and water dispersible granules, and has obvious synergism, the lasting time is long, and the bactericide is environment-friendly.
Description
Technical field
The invention belongs to technical field of pesticide, contain the composite bactericide with synergistic effect of Boscalid and chlorobenzene ether acid amides specifically.
Background technology
Boscalid (Boscalid) belongs to succinic acid ubiquinone reductase inhibitor, very strong rejection ability is had to the sprouting of spore, and with other bactericide without cross resistance, this product is the Novel tobacco acid amide fungicides developed by BASF Aktiengesellschaft, is mainly used in preventing and treating powdery mildew, gray mold, various rot, brown rot and root rot etc.
Chlorobenzene ether acid amides is Central China Normal University's pyrazol acid amide compounds newly developed, and have extraordinary effect to the common epidemic disease of cucumber, tomato, potato, downy mildew, active ingredient is novel, non-resistant.
Graw mold of tomato is that the tomato that caused by the pathogen of Botrytis cinerea (Botrytis cinerea) endangers heavier and common disease, and each vegetable-growing area all occurs.Low temperature, the time that rainy weather is many continuously endanger serious.The etching causing cauline leaf withered and a large amount of when falling ill serious, decayed fruit, directly affect output.
Summary of the invention
The object of this invention is to provide a kind of composite bactericide with synergistic effect, for preventing and treating graw mold of tomato, compared with existing pesticide control, realizing the object improving drug effect.Be specifically related to the composite bactericide of Boscalid and chlorobenzene ether acid amides.
Utilize above-mentioned composite bactericide, be equipped with the known auxiliary agent of those skilled in that art, make formulation of the present invention with the known method of those skilled in that art, formulation of the present invention is suspending agent and water dispersible granules.
In above-mentioned composite bactericide, the proportion of Boscalid and chlorobenzene ether acid amides is 1:50-50:1.
Above-mentioned composite bactericide has following characteristics: 1. use composite formula, has good synergistic effect; 2. active ingredient is novel, non-resistant; 3. sterilization is rapid, and the lasting period is long.
First applicant uses these two kinds of compositions to carry out indoor biometrics test, test method and result as follows:
First, after analyzing the action character of two kinds of active ingredients, the raw object surveyed is decided to be the pathogen of Botrytis cinerea (Botrytiscinerea) by us.
The test method of indoor biometrics: reference standard NY/T1156.6-2006, adopts growth rate method to measure medicament to the inhibitory action of graw mold of tomato pathogen mycelial growth.On the basis of preliminary experiment, from each medicament, design 5 concentration within the scope of 10%-90% are reached to germ mycelial growth inhibition rate, it is for subsequent use by the former medicine of 96% Boscalid and the former medicine of 95% chlorobenzene ether acid amides with acetone to be first that solvent is made into the liquid of series concentration, then liquid is joined in 1% ratio in the PDA medium melting also cool to room temperature, after fully shaking up, pour in the culture dish (Φ 90mm) of sterilizing and make band medicine flat board, often process and repeat, to add the process of sterile water for blank for four times; With card punch (Φ 5mm) the picking botrytis cinerea bacterium cake of sterilizing, mycelia faces down aseptic inoculation in the central authorities of band medicine flat board, be inverted in the interior cultivation of constant incubator of 25 DEG C, adopt right-angled intersection method to measure colony diameter after cultivating 6d, calculate the EC of each medicament to pathogen
50, and calculate toxicity index according to the following equation, compare virulence and the bacteriostasis of different agents.Former medicine used is tested in above-mentioned raw test and reagent is all bought from other producers.
The co-toxicity coefficient method representation that the co-toxicity of mixture preparation adopts Sun Yun abundant:
The theoretical toxicity index TTI=∑ of mixture preparation (percentage of this pharmaceutically active ingredient of the toxicity index ATI of certain medicine × in mixture).
Be synergistic effect when co-toxicity coefficient CTC is greater than 120, being antagonism when being less than 80, is addition time between 80-120.
Indoor biometrics test data sees the following form:
Table 1 Boscalid and chlorobenzene ether acid amides and different ratio thereof are to the measurement result of graw mold of tomato co-toxicity coefficient
By above-mentioned data, obviously can find out that the co-toxicity coefficient (CTC) of formula is all greater than 120, the prevention and control capability of graw mold of tomato is had to the synergistic effect of different proportion when Boscalid and chlorobenzene ether acid amides are composite in varing proportions.
Tested by indoor biometrics, determine Boscalid and chlorobenzene ether acid amides two kinds of active ingredients are composite can good synergistic effect, below by way of instantiation in order to further describe the present invention, but the present invention is absolutely not only only limitted to these embodiments following.In formula, percentage is all weight percentage, and the former medicine used and auxiliary agent are other producers and buy.
Formulation examples is as follows:
Example one, 25.5% Boscalid chlorobenzene ether amide suspending agents
Example two, 24.8% Boscalid chlorobenzene ether acid amides water dispersible granules
Example three, 22% Boscalid chlorobenzene ether amide suspending agents
Example four, 18% Boscalid chlorobenzene ether acid amides water dispersible granules
Example five, 20% Boscalid chlorobenzene ether amide suspending agents
Example six, 12% Boscalid chlorobenzene ether acid amides water dispersible granules
Example seven, 24% Boscalid chlorobenzene ether amide suspending agents
Example eight, 11% Boscalid chlorobenzene ether acid amides water dispersible granules
Example nine, 62% Boscalid chlorobenzene ether acid amides water dispersible granules
Example ten, 30.6% Boscalid chlorobenzene ether amide suspending agents
Select above example to carry out preventing and treating the field trial of graw mold of tomato, simultaneously by the Contrast on effect with Boscalid and chlorobenzene ether acid amides single dose, verify composite after synergistic effect.Test site is area, Xianyang, Shanxi province, and the time is on August 13rd, 2013, and test each process three repetition, community randomized arrangement, each plot area is 30m
2, adopt back-pack electric compression sprayer, dispenser was sunny calm for the same day, and the planting habit of planting habit all with local of all communities is identical, records the synoptic data on the dispenser same day and a week thereafter, specific as follows:
Table 2 duration of test meteorological data
Investigation method reference GB/T 17980.34-2000, each community diagonal 5 sampling, often some sampling 2-3 strain, investigate whole blade, calculate according to following grade scale:
0 grade: without scab;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for 6% ~ 10% of whole leaf area;
5 grades: lesion area accounts for 11% ~ 25% of whole leaf area;
7 grades: lesion area accounts for 26% ~ 50% of whole leaf area;
9 grades: lesion area accounts for more than 51% of whole leaf area, stem stalk there is scab.
Within after dispenser 7 days first, carry out second time dispenser, respectively after dispenser first 7 days and second time dispenser after 7 days investigation.Computing formula is as follows:
Table 3 20% Boscalid chlorobenzene ether amide suspending agents and different agents are to the preventive effect of graw mold of tomato
Analyze above-mentioned data to draw, Boscalid and chlorobenzene ether acid amides composite after, after medicine, 7 days preventive effects are all more than 70%, and Boscalid single dose 7 days preventive effects after medicine are first 41.75%, the preventive effect of chlorobenzene ether acid amides single dose is 40.53%, has good synergistic effect after visible two kinds of active ingredients are composite.And after secondary medicine 7 days, all complex preparations have all exceeded 73% to the preventive effect of graw mold of tomato, and visible composite rear preparation extended the lasting period that graw mold of tomato is prevented and treated, and control efficiency is more lasting.
Claims (2)
1. a composite bactericide, is characterized in that: active component is made up of Boscalid and chlorobenzene ether acid amides, and the weight ratio of described Boscalid and chlorobenzene ether acid amides is 1:50 ~ 50:1.
2. composite bactericide according to claim 1, is characterized in that: make suspending agent, water dispersible granules by active component and auxiliary material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410579055.2A CN104322499B (en) | 2014-10-24 | 2014-10-24 | A kind of composite bactericide |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410579055.2A CN104322499B (en) | 2014-10-24 | 2014-10-24 | A kind of composite bactericide |
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| CN104322499A true CN104322499A (en) | 2015-02-04 |
| CN104322499B CN104322499B (en) | 2015-12-30 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107279179A (en) * | 2017-07-13 | 2017-10-24 | 天津市森泰园林绿化有限公司 | The agricultural chemicals and its compound method of a kind of high-efficiency low-toxicity preventing and treating shade tree insect pest |
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| CN103980192A (en) * | 2014-01-20 | 2014-08-13 | 泰州百力化学股份有限公司 | Selective synthesis method of cyprosulfamide with different crystal forms |
| CN104012579A (en) * | 2014-06-23 | 2014-09-03 | 联保作物科技有限公司 | Sterilization composition and application thereof |
| CN104041543A (en) * | 2014-06-25 | 2014-09-17 | 无锡市崇安区科技创业服务中心 | Medicament for controlling soft rot of alocasia macrorrhiza and application method thereof |
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2014
- 2014-10-24 CN CN201410579055.2A patent/CN104322499B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009063074A2 (en) * | 2007-11-15 | 2009-05-22 | Basf Se | Fungicidal mixtures i |
| CN103980192A (en) * | 2014-01-20 | 2014-08-13 | 泰州百力化学股份有限公司 | Selective synthesis method of cyprosulfamide with different crystal forms |
| CN104012579A (en) * | 2014-06-23 | 2014-09-03 | 联保作物科技有限公司 | Sterilization composition and application thereof |
| CN104041543A (en) * | 2014-06-25 | 2014-09-17 | 无锡市崇安区科技创业服务中心 | Medicament for controlling soft rot of alocasia macrorrhiza and application method thereof |
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| 赵建江等: ""啶酰菌胺和咯菌腈对番茄灰霉病菌不同菌株的毒力"", 《河北农业科学》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107279179A (en) * | 2017-07-13 | 2017-10-24 | 天津市森泰园林绿化有限公司 | The agricultural chemicals and its compound method of a kind of high-efficiency low-toxicity preventing and treating shade tree insect pest |
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| CN104322499B (en) | 2015-12-30 |
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Address after: 102488, Beijing, Fangshan District Star Street, No. 1 hospital green sail, No. 16, building 8 Applicant after: Beijing Yanhua Yongle Biotechnology Co., Ltd. Address before: 102488 No. 8, Liangxiang, Beijing, Fangshan District Applicant before: Beijing Yanhua Yongle Biotechnology Co., Ltd. |
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Effective date of registration: 20171218 Address after: 063600 Leting County Economic Development Zone, Tangshan City, Hebei Patentee after: Yanhua Yongle (Leting) Biological Technology Co. Ltd. Address before: 102488, Beijing, Fangshan District Star Street, No. 1 hospital green sail, No. 16, building 8 Patentee before: Beijing Yanhua Yongle Biotechnology Co., Ltd. |