CN104288485A - Extract applied to ginseng and radix ophiopogonis preparation and preparation method of extract - Google Patents
Extract applied to ginseng and radix ophiopogonis preparation and preparation method of extract Download PDFInfo
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- CN104288485A CN104288485A CN201410477278.8A CN201410477278A CN104288485A CN 104288485 A CN104288485 A CN 104288485A CN 201410477278 A CN201410477278 A CN 201410477278A CN 104288485 A CN104288485 A CN 104288485A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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Abstract
The invention discloses a preparation method of an extract applied to a ginseng and radix ophiopogonis preparation. Ginseng, radix ophiopogonis and bighead atractylodes rhizome are mixed and extracted, and the method particularly comprises the following steps: (1) taking medicinal materials of ginseng, radix ophiopogonis and bighead atractylodes rhizome, of which the mass ratio is 1 to (1.5-2) to (2-2.5), and crushing the medicinal materials; (2) adding 1.2-1.5fold solid-phase dimethyl carbonate, carrying out ultrasonic treatment for 30-40 minutes, extracting at 40-45 DEG C for 50-70 minutes; recovering dimethyl carbonate at reduced pressure, filtering and separating to obtain a clear fluid and dross; (3) extracting the dross for 2-3 times by using 2-3fold ethanol solution with the volume fraction being 45%-75%, 1-2 hours a time, filtering, and recovering ethanol from filtrate until no alcohol taste, so as to obtain an extracting liquid; and (4) mixing the obtained clear liquid obtained from the step (2) with the extracting liquid obtained from the step (3). The preparation method disclosed by the invention is simple in process; the reagent is cheap and available; the extraction rate is high; the effective ingredients in the crude drugs can be well stored; and the obtained extracting solution has a good curative effect.
Description
Technical field
The present invention relates to a kind of extract, particularly a kind of extract being applied to red ginseng and ophiopogon root preparation.Belong to medical art.
Background technology
Radix Ginseng is the root of Araliaceae Radix Ginseng (Panax ginseng C.A.Mey.).Sweet, the micro-hardship of its property of medicine, flat, return lung,
Spleen, heart channel; Its effect strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promotes the production of body fluid, Fructus Alpiniae Oxyphyllae of calming the nerves.Application: vigour collapse has been demonstrate,proved, lung spleen heart syndrome of deficiency of kidney-QI, the thirsty and diabete of calentura deficiency of vital energy Tianjin wound.Its chemical composition comprises multiple ginsenoside, volatile oil, aminoacid, trace element and organic acid, saccharide, vitamin etc.
Having another name called dwarf lilyturf, book band grass Radix Ophiopogonis, is Liliaceae Ophiopogon perennial evergreen herbaceous plant.Fibrous root is more sturdy, and the top of root or middle part are often expanded becomes fusiform meat fritter.Its nature and flavor with return through: sweet, micro-hardship, is slightly cold, GUIXIN, lung, stomach warp.Its function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and for dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.Its chemical composition comprises Radix Ophiopogonis polysaccharide and Radix Ophiopogonis total saponins etc.
Now commercially there is various different types of red ginseng and ophiopogon root preparation, such as: Rhizoma Zingiberis Recens granule, for (emaciation and sallow complexion) soreness of the waist and knees, inappetence, dizziness and blurred vision, shortness of breath and palpitation, few thirsty, the neurasthenia in Tianjin; SHENMAI ZHUSHEYE, is used for the treatment of the shock of type of deficiency of both QI and YIN, coronary heart disease, viral myocarditis, chronic cardiopulmonary disease, granulocytopenia; Shenmai-dihuang ball, for deficiency of both the lung and kidney, cough and asthma, dry mouth and throat.
Effect of red ginseng and ophiopogon root preparation is approved by vast sufferer deeply, but the problem such as current red ginseng and ophiopogon root preparation extracting method ubiquity complex manufacturing, cost are high and extraction ratio is low.Further, due to the place of production and the difference in season, raw-material effective ingredient instability causes curative effect influenced.
Summary of the invention
The object of the invention is, for overcoming above-mentioned the deficiencies in the prior art, to provide a kind of extract being applied to red ginseng and ophiopogon root preparation and preparation method thereof.
For achieving the above object, the present invention adopts following technical proposals:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:1.5 ~ 2:2 ~ 2.5, pulverizes;
(2) add the DMC dimethyl carbonate of 1.2 ~ 1.5 times of solid phase weight, ultrasonic Treatment is after 30 ~ 40 minutes, in 40 ~ 45 DEG C of lixiviates 50 ~ 70 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) extracted 2 ~ 3 times by the alcoholic solution of dregs by the volume fraction 45% ~ 75% of 2 ~ 3 times amount, each 1 ~ 2 hour, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
In described step (1), the weight ratio of Radix Ginseng, Radix Ophiopogonis and the Rhizoma Atractylodis Macrocephalae is preferably 1:2:2.
In described step (2), lixiviate refers to lixiviate 2 ~ 3 times.
In described step (2), extraction temperature is preferably 40 DEG C.
In described step (2), extraction time is preferably 60 minutes.
In described step (3), the volume fraction of alcoholic solution is preferably 75%.
In described step (3), extraction time is preferably 2 hours.
Be applied to an extract for red ginseng and ophiopogon root preparation, prepare according to above-mentioned preparation method.
Beneficial effect of the present invention:
Preparation method technique of the present invention is simple, reagent is cheaply easy to get, extraction ratio is high, can be good at preserving the effective ingredient in crude drug, and gained extracting solution has good curative effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further elaborated, should be noted that following explanation is only to explain the present invention, not limiting its content.
Embodiment 1:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:2:2, pulverizes;
(2) add the DMC dimethyl carbonate of 1.2 times of solid phase weight, ultrasonic Treatment is after 30 minutes, in 40 DEG C of lixiviates 60 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 75% of 2 times amount is extracted 3 times, each 2 hours, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
Embodiment 2:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:1.5:2, pulverizes;
(2) add the DMC dimethyl carbonate of 1.5 times of solid phase weight, ultrasonic Treatment is after 40 minutes, in 45 DEG C of lixiviates 70 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 45% of 3 times amount is extracted 2 times, each 1 hour, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
Embodiment 3:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:1.5:2.5, pulverizes;
(2) add the DMC dimethyl carbonate of 1.2 times of solid phase weight, ultrasonic Treatment is after 30 minutes, in 40 DEG C of lixiviates 50 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 50% of 2 times amount is extracted 3 times, each 2 hours, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
Embodiment 4:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:2:2.5, pulverizes;
(2) add the DMC dimethyl carbonate of 1.5 times of solid phase weight, ultrasonic Treatment is after 30 minutes, in 40 DEG C of lixiviates 60 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 60% of 2 times amount is extracted 3 times, each 1.5 hours, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
Embodiment 5:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:1.5:2.5, pulverizes;
(2) add the DMC dimethyl carbonate of 1.2 ~ 1.5 times of solid phase weight, ultrasonic Treatment is after 40 minutes, in 45 DEG C of lixiviates 70 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 75% of 3 times amount is extracted 2 times, each 2 hours, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
Embodiment 6:
Being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:2:2, pulverizes;
(2) add the DMC dimethyl carbonate of 1.5 times of solid phase weight, ultrasonic Treatment is after 40 minutes, in 40 DEG C of lixiviates 50 ~ 70 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) the dregs alcoholic solution of the volume fraction 45% of 3 times amount is extracted 2 times, each 2 hours, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
test example
Solution stability testing:
The extract that embodiment 1 ~ 6 obtains, gets 2mL, canned transparent ampulla respectively, sealing, and lucifuge is placed, and 1 day, 10 days, 45 days and 90 days range estimation clarity, the results are shown in Table 1.
Table 1. solution stability testing
| Time (my god) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| 1 | Clarification | Clarification | Clarification | Clarification | Clarification | Clarification |
| 10 | Clarification | Clarification | Clarification | Clarification | Clarification | Clarification |
| 45 | Clarification | Clarification | Clarification | Clarification | Clarification | Clarification |
| 90 | Clarification | Clarification | Clarification | Clarification | Clarification | Clarification |
From table 1, the extract that embodiment 1 ~ 6 obtains has good stability, is easy to long-time preservation.
Clinical trial:
The extract that embodiment 1 obtains is concentrated, obtains extractum.Take 1g extractum every day, every day 1 time.
Patient with angina pectoris 80 example, male patient 45 example, female patient 35 example, 55 years old mean age.Stochastic averagina is assigned as two groups, and one group of extractum taken embodiment 1 extract and prepare, another group takes placebo.Time of Administration is a course for the treatment of, within 4 weeks, is a course for the treatment of.
Curative effect determinate standard:
Effective: in 10 ~ 15 days, angina pectoris attack times is less than weekly 2 times, substantially without nitroglycerin, electrocardiogram is normal;
Effective: nitroglycerin consumption reduces over half, ST section rising 50%, T ripple is made into low flat by inversion;
Invalid: nitroglycerin consumption and electrocardiogram are without improvement.Relatively clinical symptoms (blood pressure, heart rate, arrhythmia conditions) before and after two groups of treatments.
Taking embodiment 1 extract in 40 examples prepares in the patient of extractum, effective 39 examples, effective 1 example, invalid 0 example; 40 examples are taken in the patient of placebo, effective 1 example, effective 3 examples, invalid 36 examples.As can be seen here, treatment group is obviously better than placebo group, and extract of the present invention effectively can reduce the angina pectoris attacks frequency of patient, therefore medicine of the present invention effectively can treat angina pectoris.
Although above-mentioned, the specific embodiment of the present invention is described; but not limiting the scope of the invention; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Claims (8)
1. being applied to a preparation method for the extract of red ginseng and ophiopogon root preparation, it is characterized in that, is that concrete steps are as follows by Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae united extraction:
(1) get Radix Ginseng, Radix Ophiopogonis and Rhizoma Atractylodis Macrocephalae, three's weight ratio is 1:1.5 ~ 2:2 ~ 2.5, pulverizes;
(2) add the DMC dimethyl carbonate of 1.2 ~ 1.5 times of solid phase weight, ultrasonic Treatment is after 30 ~ 40 minutes, in 40 ~ 45 DEG C of lixiviates 50 ~ 70 minutes, and reclaim under reduced pressure DMC dimethyl carbonate, isolated by filtration obtains clear liquor and dregs;
(3) extracted 2 ~ 3 times by the alcoholic solution of dregs by the volume fraction 45% ~ 75% of 2 ~ 3 times amount, each 1 ~ 2 hour, filter, filtrate recycling ethanol, to without alcohol taste, obtains extracting solution;
(4) combining step (2) and step (3) gained clear liquor and extracting solution, to obtain final product.
2. preparation method according to claim 1, is characterized in that, in described step (1), the weight ratio of Radix Ginseng, Radix Ophiopogonis and the Rhizoma Atractylodis Macrocephalae is 1:2:2.
3. preparation method according to claim 1, is characterized in that, in described step (2), lixiviate refers to lixiviate 2 ~ 3 times.
4. preparation method according to claim 1, is characterized in that, in described step (2), extraction temperature is 40 DEG C.
5. preparation method according to claim 1, is characterized in that, in described step (2), extraction time is 60 minutes.
6. preparation method according to claim 1, is characterized in that, in described step (3), the volume fraction of alcoholic solution is 75%.
7. preparation method according to claim 1, is characterized in that, in described step (3), extraction time is 2 hours.
8. be applied to an extract for red ginseng and ophiopogon root preparation, it is characterized in that, prepare according to preparation method according to claim 1.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906214A (en) * | 2015-05-08 | 2015-09-16 | 福建师范大学 | Method for combined preparation of flavonoid and triterpenic acid substances in loquat leaf |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1244403A (en) * | 1998-08-07 | 2000-02-16 | 雅安三九药业有限公司 | Preparation of isotomic Shengmei injecta |
| KR20090073328A (en) * | 2007-12-31 | 2009-07-03 | 충남대학교산학협력단 | A composition comprising the processed extract of panax ginseng for the prevention and treatment of pathogenic avian influenza virus |
| CN101993462A (en) * | 2009-08-11 | 2011-03-30 | 昆明制药集团股份有限公司 | Scutellarin crystal I and preparation method thereof |
| CN103989926A (en) * | 2014-05-28 | 2014-08-20 | 王庚禹 | Extractive for preparing Shenmai injection |
-
2014
- 2014-09-18 CN CN201410477278.8A patent/CN104288485A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1244403A (en) * | 1998-08-07 | 2000-02-16 | 雅安三九药业有限公司 | Preparation of isotomic Shengmei injecta |
| KR20090073328A (en) * | 2007-12-31 | 2009-07-03 | 충남대학교산학협력단 | A composition comprising the processed extract of panax ginseng for the prevention and treatment of pathogenic avian influenza virus |
| CN101993462A (en) * | 2009-08-11 | 2011-03-30 | 昆明制药集团股份有限公司 | Scutellarin crystal I and preparation method thereof |
| CN103989926A (en) * | 2014-05-28 | 2014-08-20 | 王庚禹 | Extractive for preparing Shenmai injection |
Non-Patent Citations (3)
| Title |
|---|
| 刘树民: "《中药药物性肝损害》", 30 September 2007, 中国中医药出版社 * |
| 王志超等: "超滤法和水醇法制备参麦注射液的实验比较研究", 《中国药房》 * |
| 谢克昌等: "《甲醇工艺学》", 30 June 2010, 化学工业出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906214A (en) * | 2015-05-08 | 2015-09-16 | 福建师范大学 | Method for combined preparation of flavonoid and triterpenic acid substances in loquat leaf |
| CN104906214B (en) * | 2015-05-08 | 2018-06-19 | 福建师范大学 | The combined preparation process of flavonoids and triterpene acid in a kind of loguat leaf |
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Application publication date: 20150121 |