CN104208357B - Wound sprays Chinese herbal antibacterial liquid - Google Patents
Wound sprays Chinese herbal antibacterial liquid Download PDFInfo
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- CN104208357B CN104208357B CN201410033226.1A CN201410033226A CN104208357B CN 104208357 B CN104208357 B CN 104208357B CN 201410033226 A CN201410033226 A CN 201410033226A CN 104208357 B CN104208357 B CN 104208357B
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Abstract
The present invention relates to a kind of wound to spray Chinese herbal antibacterial liquid, and to solve the problems, such as that existing disinfectant irritation is strong, it is that following bulk drugs alcohol precipitation extract first converts 7 11 times of weight pure water and obtains water-soluble active compound, then blends and be made into loose square-bottomed bamboo basket acid sodium；Following bulk drugs alcohol precipitation extract is first blended into a part of pure water and obtains water-soluble active compound, the loose square-bottomed bamboo basket acid sodium aqueous solution after another part pure water of loose square-bottomed bamboo basket acid sodium will be blended into again being blended into the water-soluble active compound and be made, the weight ratio of the alcohol precipitation extract and two parts pure water is 1: 7 11；The weight ratio of loose square-bottomed bamboo basket acid sodium and the water-soluble active compound is 1.5 3: 1000；The bulk pharmaceutical chemicals weight proportion is：Herba Andrographitis 50 110, Cortex Phellodendri 50 110, radix berberidis 40 100, Celastrus angulatus 40 100, Radix Isatidis 40 100, kuh-seng 40 100, the root bark of white mulberry 40 80, santonin 40 80, aloe 40 80, the fruit of Cherokee rose 40 80, akebi 40 80, subprostrate sophora 40 80, Sichuan Citrus reticuiata Blano 30 70, rheum officinale 30 70, corydalis tuber 30 70, radix glycyrrhizae 30 70.It is small with irritation, Disinfection Effect length, short treating period, it is easy to use the advantages of.
Description
Technical field
The present invention relates to a kind of wound disinfectant, sprays Chinese herbal antibacterial liquid more particularly to a kind of wound.
Background technology
Often irritation is strong for the common sterilizing disinfectant of wound at present, such as hydrogen peroxide, alcohol, and Disinfection Effect is of short duration, no
It is easy to use.
The content of the invention
Present invention aims to overcome that the drawbacks described above of the prior art, there is provided a kind of irritation is small, and effect is longer, conveniently makes
Wound sprays Chinese herbal antibacterial liquid.
To achieve the above object, wound spray Chinese herbal antibacterial liquid of the present invention is that following bulk drugs alcohol precipitation extract first converts 7-11
Times of weight pure water obtains water-soluble active compound, then blends and be made into loose square-bottomed bamboo basket acid sodium；Or following bulk drugs alcohol precipitation extract converts 7-11 weights
The pure water that amount dissolves in loose square-bottomed bamboo basket acid sodium again is made；Or following bulk drugs alcohol precipitation extract be first blended into a part of pure water obtain it is water-soluble
Active compound, then the loose square-bottomed bamboo basket acid sodium aqueous solution after another part pure water of loose square-bottomed bamboo basket acid sodium will be blended into be blended into the water-soluble active compound and make
, the weight ratio of the alcohol precipitation extract and two parts pure water is 1: 7-11；
The weight ratio of loose square-bottomed bamboo basket acid sodium and the water-soluble active compound is 1.5-3: 1000；The bulk pharmaceutical chemicals weight proportion is：Punching
Lotus 50-110, Cortex Phellodendri 50-110, radix berberidis 40-100, Celastrus angulatus 40-100, Radix Isatidis 40-100, kuh-seng 40-100, the root bark of white mulberry
40-80, santonin 40-80, aloe 40-80, fruit of Cherokee rose 40-80, akebi 40-80, subprostrate sophora 40-80, the red withered skin 30- in Sichuan
70th, rheum officinale 30-70, corydalis tuber 30-70, radix glycyrrhizae 30-70.
Composition principle：
First, monarch drug in a prescription；Play the medicine of primary treatment for main disease or main symptom, in the side of being it is indispensable mainly.Monarch
Medicine；Herba Andrographitis, Cortex Phellodendri.Nature and flavor；It is bitter, cold.Function；It is clearing heat and detoxicating, cool blood, detumescence, eliminating dampness.With to staphylococcus aureus,
Green purulence bacillus, proteus, Diplococcus pneumopniae, hemolytic streptococcus, shigella dysenteriae, typhoid bacillus, gram-positive bacteria, leather are blue
Family name's negative bacterium, and influenza virus, arboviruse, Si adenositis diseases have inhibitory action, can strengthen human leukocytes and bacterium is gulped down
Ability is bitten, immune function can be increased, there is obvious antipyretic response.It is the indispensable monarch drug in a prescription of main side；Herba Andrographitis, Cortex Phellodendri.
Two ministerial drugs；There are two kinds of meanings.Ministerial drug；Radix berberidis, Celastrus angulatus, Radix Isatidis, kuh-seng.Nature and flavor；It is bitter, cold, function；Heat-clearing
Eliminating dampness, purging intense heat and detonicating, sterilization, desinsection.
1st, monarch drug in a prescription is aided in strengthen the main disease for the treatment of or main symptom.With clearing heat and detoxicating.Resisting pathogenic microbes acts on, to dysentery bar
Bacterium, typhoid bacillus, tubercle bacillus, staphylococcus aureus, hemolytic streptococcus, a variety of pathogenic bacterias and dermatophyte and hook end
Conveyor screw etc. has inhibitory action.
2nd, primary treatment is played for simultaneous disease or simultaneous disease.With heat-clearing and damp-drying drug, purging intense heat and detonicating.To Staphylococcus aureus
Bacterium, hemolytic streptococcus, Diplococcus pneumopniae, shigella dysenteriae, Escherichia coli , Green purulence bacillus, proteus, concentric hair moss bacterium, is permitted
Lan Shi Huang moss bacterium, the small gemma moss bacterium of rust, the small gemma moss bacterium of ulotrichy, groin epidermis moss bacterium, star nocardia have
Inhibitory action.Can also strong inhibition Candida albicans, it is antitumor, increasing leukocyte etc. effect.
3rd, adjutant；There are three kinds of meanings.Adjutant；The root bark of white mulberry, santonin, aloe, the fruit of Cherokee rose, akebi, subprostrate sophora.Nature and flavor；
It is pungent, sweet, flat, bitter, cold.Function；Clearing heat and detoxicating, reducing pharyngeal swelling, coordinating the drug actions of a prescription, neutralizes a toxin.
1st, supplementary drug；Coordinate monarch, ministerial drug to strengthen therapeutic effect, or the directly medicine for the treatment of minor symptom.Function；Clearly
Thermal detoxification, desinsection.Help monarch, minister phase and, make；Monarch, minister strengthen treatment or directly treat minor symptom.With to typhoid bacillus, greatly
Enterobacteria, tubercle bacillus, shigella dysenteriae, staphylococcus aureus.Hemolytic streptococcus, comma bacillus, Mycobacterium leprae, Ru shape tables
Dermatophytes, Candida albicans, dermatophyte and Leptospira, gram-positive bacteria, Gram-negative bacteria, pruitus etc.
Disease has inhibitory action.
2nd, supplementary inhibitory medicine；I.e. eliminating or weaken monarch, the toxicity of ministerial drug, or monarch can be restricted, the strong property of ministerial drug thing (strong)
Medicine.Function；It is clearing heat and detoxicating.With elimination or weaken monarch, the toxicity of ministerial drug, while restrict monarch, the strong property of ministerial drug thing (strong).Side
The composition of agent；With with hundred medicines, solution hundred poison effects.The effect of mediation property of medicine can be played in prescription；By removing toxic substances, can reduce
The malicious strong property of medicine in prescription.With to hemolytic streptococcus, staphylococcus aureus, typhoid bacillus, corynebacterium diphtheriae, dysentery
The a variety of pathogenic coccuses and bacillus such as bacillus, Escherichia coli , Green purulence bacillus, bacillus enteritidis, clostridium tetani have bacteriostasis.
Have at the same time and eliminate medicine in prescription or weaken the effect such as toxin of prescription Chinese medicine.It is nontoxic to human body, harmless, without side-effects, nothing
Dependence.
3rd, corrigent；Very, when may refuse to take medicine, adapted is opposite with monarch drug in a prescription nature and flavor and can rise in the treatment identical for i.e. seriously ill heresy
The medicine of effect.Function；It is clearing heat and detoxicating.Adapted fruit of Cherokee rose nature and flavor；It is sour, puckery, flat.Corydalis tuber nature and flavor；Acrid, bitter, warm.Although with monarch
Pharmacological property taste it is opposite but have an enhancing and synergy monarch drug in a prescription sterilize jointly, desinsection, antiviral strength.With to gram-positive bacteria
And Gram-negative bacteria, shigella dysenteriae, Escherichia coli, Leptospira and influenza virus have inhibitory action.
4th, medicine is made；There are three kinds of meanings.Adjutant；Sichuan Citrus reticuiata Blano, rheum officinale, corydalis tuber, radix glycyrrhizae.Nature and flavor；It is pungent, bitter, sweet, warm,
It is flat.Function；It is clearing heat and detoxicating, promoting blood circulation and removing blood stasis, coordinating the drug actions of a prescription.With with hundred medicines, solution hundred poison effects.(collected statements on the herbal foundation) " and middle benefit
Gas, the medicine of qi-restoratives removing toxic substances ".
1st, guiding drug；Can in the side of drawing all medicines to disease medicine.Function；Heat-clearing and damp-drying drug, purging intense heat and detonicating.With introducing side
Medicine in agent, help monarch, minister, help, make medicine phases and, make monarch, minister, help, make medicine composition prescription share synergistic effect, can strengthen or increase
Imitate antibacterial, antiviral effect.With to a variety of gram-positive bacterias, Gram-negative bacteria and anti-tetanus toxin, anti-inflammatory,
Antibacterial, antiprotozoan, antiviral grade have inhibitory action.
2nd, harmonizing drug；There is the medicine of all medicine effects in reconciliation side.Function；Eliminating dampness, promoting blood circulation, promoting the circulation of qi, analgesic.With with
The effect of hundred medicines, the poison of solution hundred.It can reconcile the effect of medicine in prescription, help monarch, minister, help, close medicine phases, make monarch, minister, help, make medicine
Medicine plays reconciliation effect in prescription, strengthens shared synergistic effect, can strengthen or synergistic antimicrobial, antiviral effect.
Book on Chinese herbal medicine just " taste to hardship, the property that must be neutralized, therefore the solution that obtains of poison its malicious, the sum of firm medicine obtains its property ".
Prove after testing：Medical instrument of the present invention has to a variety of gram-positive bacterias, Gram-negative bacteria, Staphylococcus aureus
Bacterium, bacillus enteritidis , Green purulence bacillus and dermatophyte have inhibitory action.Anti- Amoeba, kills Trichomonas vaginalis.Medicine of the present invention
Also there is the advantages of irritation is small, and effect is longer, easy to use.
As an optimization, the bulk pharmaceutical chemicals weight proportion is：Herba Andrographitis 80, Cortex Phellodendri 80, radix berberidis 70, Celastrus angulatus 70, plate are blue
It is root 70, kuh-seng 70, the root bark of white mulberry 60, santonin 60, aloe 60, the fruit of Cherokee rose 60, akebi 60, subprostrate sophora 60, the red withered skin 50 in Sichuan, big
Huang 50, corydalis tuber 50, radix glycyrrhizae 50.
As an optimization, the extract is blended into the pure water or the alcohol precipitation extract and described two parts of 9 times of weight
The weight ratio of pure water is 1: 9；The weight ratio of loose square-bottomed bamboo basket acid sodium and the water-soluble active compound is 2: 1000.
As an optimization, the alcohol precipitation extraction in turn includes the following steps：Bulk pharmaceutical chemicals removal of impurities-rinsing-boiling-concentration -ol sinks-
Recycling ethanol is made.
As an optimization, the boiling is that the bulk pharmaceutical chemicals after rinsing add water boiling, filter to get filtrate, and the concentration is the filter
Liquid is concentrated to give concentrate, and the alcohol precipitation is that alcohol precipitation extract is made when small with 75% ethanol alcohol precipitation 48 in the concentrate.
Fabrication processing is；Offerd medicine → cleaned by recipe quantity (mainly soil is miscellaneous) → rinsing → boiling (kingfisher takes) → concentration
→ alcohol precipitation (48 it is small when, alcohol precipitation use 75% ethanol) → recycling ethanol → storage → storage → use.The number of converted pure water
The quantity of amount or converted pure water and loose square-bottomed bamboo basket acid sodium preferably satisfies one ton of Chinese herbal medicine, produces one ton of present invention disinfection liquid.System
Into antimicrobial fluid of the present invention be distributed into spray bottle, every bottle preferably fills 20 milliliters.
Medicine use scope of the present invention：Sterilized available for wound, disinfection before injecting, pre-operation sterilization, Medical treatment device is guarded against disinfection, flown
Sterilized in passenger cabin, disinfection in passenger car, disinfection in bus, disinfection in taxi, disinfection in swimming pool, public place
Interior disinfection, sterilizes in restaurant, table ware, in family, cleaning vegetable disinfectant etc..
Invention antimicrobial fluid of the present invention, through " China Academy of TCM " and " the antibacterial examination of Beijing legendary god of farming's pharmaceutical developments research institute
Test ", " basis institute of Beijing University of Chinese Medicine microbiology, immunology teaching and research room " extracorporeal bacteria inhibitor test and " Chinese medicine section
Institute, Institute of Medicinal Biological Technique " examining report proves；To gram-positive bacteria, Gram-negative bacteria, bacterium, brood cell bacterium
And fungi (such as Candida albicans, black-koji mould) has very strong suppression function.What particularly gynaecology's incidence was very high reads coccus
Property vaginitis disease mycoplasma --- Candida albicans, and the gonococcus to gonorrhoea, cervical erosion, urea decomposes mycoplasma, sense
The virus of condyloma acuminatum is contaminated, infecting phallic herpes simplex virus has very strong inhibitory action.Clinical application proves that effective percentage reaches
Absolutely.
After adopting the above technical scheme, wound spray Chinese herbal antibacterial liquid of the present invention has, irritation is small, and Disinfection Effect length, is treated
Journey is short, it is easy to use the advantages of.
Embodiment
Wound spray Chinese herbal antibacterial liquid of the present invention is that following bulk drugs alcohol precipitation extract converts 7 or 9 or 11 times of weight
Pure water obtains water-soluble active compound, then blends that loose square-bottomed bamboo basket acid sodium is made or the loose square-bottomed bamboo basket acid sodium is first dissolved into the pure water, then
Obtained loose square-bottomed bamboo basket acid sodium aqueous solution and the alcohol precipitation extract is miscible obtained.(it can also be or following bulk drugs alcohol precipitation carries
Take thing to be first blended into a part of pure water and obtain water-soluble active compound, then the loose square-bottomed bamboo basket acid sodium after another part pure water of loose square-bottomed bamboo basket acid sodium will be blended into
Aqueous solution is blended into the water-soluble active compound and is made, and the weight ratio of the alcohol precipitation extract and two parts pure water is 1: 7-
11)。
The weight ratio of loose square-bottomed bamboo basket acid sodium and the water-soluble active compound is 1.5 or 2 or 3: 1000；The quantity of converted pure water
Or the quantity of converted pure water and loose square-bottomed bamboo basket acid sodium preferably satisfies one ton of Chinese herbal medicine, one ton of present invention disinfection liquid is produced.
The bulk pharmaceutical chemicals weight proportion is A：50 kilograms of Herba Andrographitis, 110 kilograms of Cortex Phellodendri, 40 kilograms of radix berberidis, Celastrus angulatus 100
Kilogram, 40 kilograms of Radix Isatidis, 100 kilograms of kuh-seng, 40 kilograms of the root bark of white mulberry, 80 kilograms of santonin, 40 kilograms of aloe, the fruit of Cherokee rose 80 it is public
Jin, 40 kilograms of akebi, 80 kilograms of subprostrate sophora, red withered 30 kilograms of the skin in Sichuan, 70 kilograms of rheum officinale, 30 kilograms of corydalis tuber, radix glycyrrhizae 70 are public
Jin.
The bulk pharmaceutical chemicals weight proportion is B：110 kilograms of Herba Andrographitis, 50 kilograms of Cortex Phellodendri, 100 kilograms of radix berberidis, Celastrus angulatus 40
Kilogram, 100 kilograms of Radix Isatidis, 40 kilograms of kuh-seng, 80 kilograms of the root bark of white mulberry, 40 kilograms of santonin, 80 kilograms of aloe, the fruit of Cherokee rose 40 it is public
Jin, 80 kilograms of akebi, 40 kilograms of subprostrate sophora, 70 kilograms of Sichuan Citrus reticuiata Blano, 30 kilograms of rheum officinale, 70 kilograms of corydalis tuber, radix glycyrrhizae 30 are public
Jin.
The bulk pharmaceutical chemicals weight proportion is C：80 kilograms of Herba Andrographitis, 80 kilograms of Cortex Phellodendri, 70 kilograms of radix berberidis, Celastrus angulatus 70 are public
Jin, 70 kilograms of Radix Isatidis, 70 kilograms of kuh-seng, 60 kilograms of the root bark of white mulberry, 60 kilograms of santonin, 60 kilograms of aloe, 60 kilograms of the fruit of Cherokee rose,
60 kilograms of akebi, 60 kilograms of subprostrate sophora, 50 kilograms of Sichuan Citrus reticuiata Blano, 50 kilograms of rheum officinale, 50 kilograms of corydalis tuber, 50 kilograms of radix glycyrrhizae.
The alcohol precipitation extraction in turn includes the following steps：Ethanol is recycled in bulk pharmaceutical chemicals removal of impurities-rinsing-boiling-concentration -ol is sunk-
It is made.The boiling is that the bulk pharmaceutical chemicals after rinsing add water boiling, filter to get filtrate, and the concentration is that the filtrate is concentrated to give concentration
Thing, the alcohol precipitation are that alcohol precipitation extract is made when small with 75% ethanol alcohol precipitation 48 in the concentrate.
Laboratory detection result using the medicine of the present invention of above-mentioned technical proposal is as follows：
There are following three kinds for the medicine of the present invention of experiment or clinical observation：That is, convert 11 times of weight pure water, loose square-bottomed bamboo basket acid sodium with
The weight ratio of the water-soluble active compound is 1.5: 1000 and while using the bulk pharmaceutical chemicals weight proportion to be matched for above-mentioned A is obtained
Medicine of the present invention is No. 1 medicine；The weight ratio for converting 9 times of weight pure water, loose square-bottomed bamboo basket acid sodium and the water-soluble active compound is 3: 1000 and adopts
It is that obtained medicine of the present invention is No. 2 medicines when above-mentioned B is matched with the bulk pharmaceutical chemicals weight proportion；Convert 7 times of weight pure water, loose square-bottomed bamboo basket acid
Sodium and the weight ratio of the water-soluble active compound are 2: 1000 and are made when using the bulk pharmaceutical chemicals weight proportion to be matched for above-mentioned B
Medicine of the present invention be No. 3 medicines.
Using 1), positive strain：Cured sample bacillus, hay bacillus, staphylococcus 209P, sarcine.2), negative strain：
Escherichia coli 0-111, Pseudomonas aeruginosa, proteus X0-19, Friedlander's bacillus.3) fungi：Candida albicans, aspergillus niger
Bacterium.
Using culture medium：1), bacterium：Broth bouillon.2), fungi：Sabouraud culture mediums.
Experimental method：Liquid dilution method.
Experimental result：
Note：MIC is minimum inhibitory concentration.
Medicine of the present invention is used to treat the ulcus cruris trauma infection contamination surface of a wound and 20 clinical observation materials of Prepuce balanitis are as follows：
It is that the surface of a wound and glans penis, posthitis external application or part are formed to the scorching merging ulcer of shank vein, wound postoperative infection below
Painting washes 20, obtains promising result.Now it is reported as follows：
First, clinical data
1. shank vein is scorching to merge ulcer 6
(1) Lee is high, man, 68 years old：Left leg inside lower end is red, swollen, hot, pain 3 days.Its inflammation center ulcer area 4 ×
3cm。
(2) Mr. Wang's meeting, man, 61 years old：Ankle festers 2 days, 5 × 3cm of area in left leg, and periphery is red and swollen, Pi Wengao.
(3) certain benevolence is closed, man, 78 years old：Right lower extremity merges inside and outside ankle point, sheet ulcer 10 because of varication+My god, big person
About 1.5 × 1cm.
(4) going into business, certain is spent, female, 56 years old：Right lower extremity phlebitis merges ulcer 3 days, and ulcer area is about：5×3cm.
(5) Chen's age, man, 70 years old：The scorching merging point of left leg lateral superficial veins, sheet are festered two weeks, area 12 × 7.
T：37℃.
(6) Zhang's stamen, female, 67 years old：For many years, skin is brown for double lower limb lower end superficial phlebitis, is dispersed in point, sheet ulcer warp
It is not cured long.37 DEG C of body temperature.
2. the trauma infection contamination surface of a wound 2：
(1) Mr. Wang, male, 19 years old：Right hand trauma infection contamination 7 days, right hand back of the body outside 3 × 2.5cm of the surface of a wound, wound granulation is gloomy,
It is stale.
(2) soldier Lee, man, 26 years old：Left thigh is because traffic accident wound is gone through, and trauma surface infestation 10 days, the surface of a wound about 6 × 3cm, is not cured
Close.
3. foreskin, balanitis 12：
(1) going into business, certain is outstanding, man, 21 years old：Foreskin, glans penis are red, swollen, and nothing is festered.
(2) Mr. Wang woods, man, 28 years old：Strip ulcer 10 at main cause glans penis, coronary sulcus+My god, face 0.5 × 0.5,0.5 ×
0.3cm, at a big young waiter in a wineshop or an inn.
(3) Lee wins, man, 18 years old：It is scratchy at foreskin, glans penis, micro- red and swollen pain 2 days.
(4) Lee, man, 24 years old：Needle point size papule 2 days, itch at main cause glans penis, coronary sulcus.
(5) Chen mountain, man, 20 years old：Foreskin length cannot turn to more than coronary sulcus outside, cause foreskin red, 1 day swollen.
(6) Guo is complete, man, 19 years old：Glans penis, coronal place's ditch needle point size papule 4 days, and mild redness.
(7) Lee mountain, man, 36 years old：Foreskin is grown, but can be turned to more than coronary sulcus.Feel local scratchy, mild redness, hat
Being dissipated at shape ditch has papule.
(8) Zhang, man, 30 years old：It is red and swollen after foreskin bite by mosquitos, rear diabrosis stream yellow water, itch etc..
(9) journey river, man, 19 years old：Redundant prepuce causes local infection, scratchy etc..
(10) Chen gives birth to, man, 24 years old：Redundant prepuce, dissipating at coronary sulcus has papule, rubescent.
(11) Chen, man, 29 years old：Uncomfortable, itch at main cause foreskin, glans penis, red and swollen, papule a couple of days at crown head.
(12) face strength, man, 23 years old：Glans penis, posthitis, itch, papule at coronary sulcus.
2nd, treatment method
For forming trauma surface infestation after ulcer and wound because shank vein is scorching, medicine spray 20-30ml of the present invention is applied daily,
3-4 times/day of sprayed coating, is used in conjunction 2-3 weeks, wherein 2 have been used antibiotic 1 week because fever adds.For foreskin, balanitis using local
Cleaning, spraying.10-20ml, secondary 3/ day.1-2,3-4,5-6 use respectively wherein in the scorching merging ulcer 6 of shank vein
Above-mentioned 1,2, No. 3 medicine.The the 1st, 2 in the trauma infection contamination surface of a wound 2 uses the above-mentioned 2nd, No. 3 medicine respectively.Foreskin, balanitis 12
In 1-4,5-8,9-12 medicine use the 1st, 2, No. 3 medicine respectively.
3rd, efficacy determination
Convulsion is cured：Ulcus cruris inflammation is complete to healing, wound wound healing.Foreskin, glans penis, glans penis inflammatory resolution, papule disappear
Lose, itch disappears.Improve：The wound ulcus cruris surface of a wound is closed or reduced substantially.It is invalid：It is substantially change through 2-3 weeks treatment nothing.
4th, result
Above-mentioned treatment, to ulcus cruris cure rate up to 83.%, only 1 (16.%) improves not yet complete to closure.Outer sentiment
Contaminate the surface of a wound and be absolutely cured platform, 100% regression is reached to foreskin, glans penis inflammation and itch.Subordinate list is as follows：
5th, discuss
It is that comparison is stranded Huaihe River for the scorching clinical treatment for merging ulcer of shank vein, is treated using medicine of the present invention, through outpatient service
Observation treatment shank vein merges leakage ulcer 6, fully recovers 5,1 is clearly better.Trauma surface infestation best results after treatment wound, reach
To absolutely.Foreskin, balanitis, papule, itch effect are also satisfied with.Medicine of the present invention can substitute general externally used antimicrobial liquid,
Externally used antimicrobial element, plays the flushing cleaning surface of a wound, anti-corrosion, convergence, antibacterial or antibacterial purpose, and can promote to create wound contraction, close
Close, cell increase the effect of, and it is nontoxic, without side effects such as allergy.Can be with large-scale popularization application.Prompting：Such as serious trauma surface infestation,
Ulcer, which merges constitutional symptom person, should coordinate antibiotic complex treatment, can more shorten the course for the treatment of.
Claims (4)
1. a kind of wound sprays Chinese herbal antibacterial liquid, it is characterised in that it is pure that following bulk drugs alcohol precipitation extract first converts 7-11 times of weight
Water obtains water-soluble active compound, then blends and be made into usnic acid sodium；Or following bulk drugs alcohol precipitation extract converts 7-11 times of weight and dissolves in pine
The pure water of trailing plants acid sodium is made；Or following bulk drugs alcohol precipitation extract is first blended into a part of pure water and obtains water-soluble active compound, then will
It is blended into the sunglo acid sodium aqueous solution after another part pure water of usnic acid sodium and is blended into the water-soluble active compound obtained, the alcohol precipitation
The weight ratio of extract and two parts pure water is 1: 7-11；
The weight ratio of usnic acid sodium and the water-soluble active compound is 1.5-3: 1000；The bulk pharmaceutical chemicals weight proportion is：Herba Andrographitis 50-
110th, Cortex Phellodendri 50-110, radix berberidis 40-100, Celastrus angulatus 40-100, Radix Isatidis 40-100, kuh-seng 40-100, root bark of white mulberry 40-80,
Santonin 40-80, aloe 40-80, fruit of Cherokee rose 40-80, akebi 40-80, subprostrate sophora 40-80, Sichuan Citrus reticuiata Blano 30-70, rheum officinale
30-70, corydalis tuber 30-70, radix glycyrrhizae 30-70；
The alcohol precipitation extraction in turn includes the following steps：Bulk pharmaceutical chemicals removal of impurities-rinsing-boiling-concentration -ol is sunk-is recycled ethanol and is made.
2. antimicrobial fluid according to claim 1, it is characterised in that the bulk pharmaceutical chemicals weight proportion is：Herba Andrographitis 80, Cortex Phellodendri 80,
Radix berberidis 70, Celastrus angulatus 70, Radix Isatidis 70, kuh-seng 70, the root bark of white mulberry 60, santonin 60, aloe 60, the fruit of Cherokee rose 60, akebi 60, mountain
Beans root 60, Sichuan Citrus reticuiata Blano 50, rheum officinale 50, corydalis tuber 50, radix glycyrrhizae 50.
3. antimicrobial fluid according to claim 1, it is characterised in that the extract is blended into the pure water or described of 9 times of weight
The weight ratio of alcohol precipitation extract and two parts pure water is 1: 9；Usnic acid sodium and the weight ratio of the water-soluble active compound are 2:
1000。
4. according to claims 1 or 2 or 3 antimicrobial fluids, it is characterised in that the boiling is that the bulk pharmaceutical chemicals after rinsing add
Water boiling, filter to get filtrate, and the concentration is that the filtrate is concentrated to give concentrate, and the alcohol precipitation is the concentrate with 75%
Alcohol precipitation extract is made in ethanol alcohol precipitation 48 when small.
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| CN102578170A (en) * | 2012-01-11 | 2012-07-18 | 蔡葵荣 | Chinese herbal medicinal bactericide |
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