CN104204766B - 微芯片型光学测量装置及其光学位置调整方法 - Google Patents

微芯片型光学测量装置及其光学位置调整方法 Download PDF

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Publication number
CN104204766B
CN104204766B CN201380016177.4A CN201380016177A CN104204766B CN 104204766 B CN104204766 B CN 104204766B CN 201380016177 A CN201380016177 A CN 201380016177A CN 104204766 B CN104204766 B CN 104204766B
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light
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CN104204766A (zh
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村木洋介
大塚史高
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Sony Corp
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    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00Programme-control systems
    • G05B19/02Programme-control systems electric
    • G05B19/18Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form
    • G05B19/19Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by positioning or contouring control systems, e.g. to control position from one programmed point to another or to control movement along a programmed continuous path
    • G05B19/27Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by positioning or contouring control systems, e.g. to control position from one programmed point to another or to control movement along a programmed continuous path using an absolute digital measuring device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484Optical investigation techniques, e.g. flow cytometry microstructural devices
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00Computing arrangements based on specific mathematical models
    • G06N7/01Probabilistic graphical models, e.g. probabilistic networks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1452Adjustment of focus; Alignment

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Manufacturing & Machinery (AREA)
  • Automation & Control Theory (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Analysis (AREA)
  • Data Mining & Analysis (AREA)
  • Computational Mathematics (AREA)
  • Artificial Intelligence (AREA)
  • Algebra (AREA)
  • Probability & Statistics with Applications (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201380016177.4A 2012-03-30 2013-01-28 微芯片型光学测量装置及其光学位置调整方法 Active CN104204766B (zh)

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JP2012-080472 2012-03-30
JP2012080472 2012-03-30
PCT/JP2013/051800 WO2013145836A1 (ja) 2012-03-30 2013-01-28 マイクロチップ型光学測定装置及び該装置における光学位置調整方法

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CN104204766A CN104204766A (zh) 2014-12-10
CN104204766B true CN104204766B (zh) 2016-08-31

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US (3) US9915935B2 (enExample)
JP (3) JPWO2013145836A1 (enExample)
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Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5994337B2 (ja) 2012-03-30 2016-09-21 ソニー株式会社 微小粒子分取装置及びディレイタイム決定方法
WO2013145836A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 マイクロチップ型光学測定装置及び該装置における光学位置調整方法
JP5924077B2 (ja) 2012-03-30 2016-05-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法
WO2013145905A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 微小粒子分取装置及び該装置における流体ストリーム最適化方法
JP6065527B2 (ja) 2012-11-08 2017-01-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
JP6304034B2 (ja) 2013-01-28 2018-04-04 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
EP2955512B1 (en) 2013-02-08 2018-10-24 Sony Corporation Microparticle analyzing device and microparticle analyzing system
EP3035030B1 (en) 2013-10-16 2019-07-10 Sony Corporation Particle fractionation device, particle fractionation method, and program
JP6136843B2 (ja) 2013-10-17 2017-05-31 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
WO2016094065A1 (en) * 2014-12-12 2016-06-16 Becton, Dickinson And Company Methods for aligning a light source with a flow stream and systems thereof
CN105988579A (zh) * 2015-03-06 2016-10-05 北京智谷睿拓技术服务有限公司 设备间相对位置调整方法及调整装置
CZ2015590A3 (cs) * 2015-08-31 2017-04-12 Wolf & Danniel S.R.O. Způsob provádění průtokového cytometrického měření
US10466158B2 (en) * 2017-04-11 2019-11-05 Sony Corporation Microparticle sorting apparatus and delay time determination method
US10591400B2 (en) 2018-03-29 2020-03-17 Sony Corporation Micro particle analyzer and micro particle analysis method
WO2019207988A1 (ja) * 2018-04-25 2019-10-31 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
JP7070797B2 (ja) * 2019-05-29 2022-05-18 株式会社島津製作所 光散乱検出装置
US11965811B2 (en) 2019-07-16 2024-04-23 Allied Flow Inc. Particle sorting apparatus and method of aligning flow cell
JP7683484B2 (ja) 2019-11-06 2025-05-27 ソニーグループ株式会社 位置調整方法、微小粒子分析装置、及びプログラム
JP7473185B2 (ja) * 2020-07-06 2024-04-23 シンクサイト株式会社 フローサイトメータ、イメージング装置、位置検出方法、及びプログラム
JP7566302B2 (ja) * 2020-07-06 2024-10-15 シンクサイト株式会社 フローサイトメータ、観測対象物判別方法、及びプログラム
CN113252633B (zh) * 2021-07-14 2021-10-12 季华实验室 一种液相芯片分析仪的质控检测方法及标准盘
WO2023062831A1 (ja) * 2021-10-15 2023-04-20 シンクサイト株式会社 フローサイトメータ、位置算出方法、及びプログラム

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004257756A (ja) * 2003-02-24 2004-09-16 Nippon Koden Corp フローセル位置決め方法およびフローセル位置調整可能なフローサイトメータ
JP2006242849A (ja) * 2005-03-04 2006-09-14 Mitsui Eng & Shipbuild Co Ltd 試料液流の位置制御方法および装置
JP2010286292A (ja) * 2009-06-10 2010-12-24 Sony Corp 微小粒子測定装置
JP4805417B1 (ja) * 2010-03-31 2011-11-02 古河電気工業株式会社 光情報解析装置及び光情報解析方法
JP2012047464A (ja) * 2010-08-24 2012-03-08 Sony Corp 微小粒子測定装置及び光軸補正方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6129737A (ja) 1984-07-20 1986-02-10 Canon Inc 粒子解析装置
JPS6236542A (ja) * 1985-08-09 1987-02-17 Canon Inc 粒子解析装置
JPS62100643A (ja) 1985-10-28 1987-05-11 Canon Inc 粒子解析装置
JPS6412245A (en) * 1987-07-03 1989-01-17 Canon Kk Particle analyzing device
US5700692A (en) 1994-09-27 1997-12-23 Becton Dickinson And Company Flow sorter with video-regulated droplet spacing
US6406848B1 (en) * 1997-05-23 2002-06-18 Lynx Therapeutics, Inc. Planar arrays of microparticle-bound polynucleotides
US5602039A (en) 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
JP3258889B2 (ja) * 1996-01-11 2002-02-18 株式会社堀場製作所 散乱式粒度分布測定装置における光軸調整方法
US6538229B1 (en) * 1996-05-08 2003-03-25 Infineon Technologies Ag Method for the positionally accurate adjustment and fixing of a microoptical element
JP3736007B2 (ja) * 1997-03-03 2006-01-18 株式会社島津製作所 マイクロチップ電気泳動装置
GB2326229A (en) * 1997-06-13 1998-12-16 Robert Jeffrey Geddes Carr Detecting and analysing submicron particles
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
US6372506B1 (en) 1999-07-02 2002-04-16 Becton, Dickinson And Company Apparatus and method for verifying drop delay in a flow cytometer
EP1245944B1 (en) * 2001-03-29 2007-02-14 Sysmex Corporation Flow cytometer
US6941005B2 (en) 2002-11-01 2005-09-06 Coulter International Corp. Monitoring and control of droplet sorting
US7133132B2 (en) * 2003-09-19 2006-11-07 The Regents Of The University Of California Light-force sensor and method for measuring axial optical-trap forces from changes in light momentum along an optic axis
US7232687B2 (en) 2004-04-07 2007-06-19 Beckman Coulter, Inc. Multiple sorter monitor and control subsystem for flow cytometer
JP4304120B2 (ja) 2004-04-30 2009-07-29 ベイバイオサイエンス株式会社 生物学的粒子をソーティングする装置及び方法
US7575589B2 (en) * 2006-01-30 2009-08-18 Photothera, Inc. Light-emitting device and method for providing phototherapy to the brain
US8343428B2 (en) * 2007-10-29 2013-01-01 Rohm Co., Ltd. Microchip and method of using the same
US8290625B2 (en) 2007-04-04 2012-10-16 Beckman Coulter, Inc. Flow cytometer sorter
JP5536995B2 (ja) * 2007-07-17 2014-07-02 オリンパス株式会社 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム
US8075853B2 (en) * 2007-11-16 2011-12-13 Rohm Co., Ltd. Microchip
JP2009156659A (ja) * 2007-12-26 2009-07-16 Olympus Corp 測定装置及び測定方法
JP5202971B2 (ja) * 2008-01-28 2013-06-05 オリンパス株式会社 測定装置及び測定方法
WO2010085632A2 (en) * 2009-01-23 2010-07-29 University Of Washington Virtual core flow cytometry
JP5487638B2 (ja) 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
US8223445B2 (en) * 2009-09-21 2012-07-17 Cytopeia Lens positioning apparatus
US9057676B2 (en) * 2010-02-05 2015-06-16 Cytonome/St, Llc Multiple flow channel particle analysis system
JP5437148B2 (ja) 2010-04-23 2014-03-12 ベイバイオサイエンス株式会社 フローサイトメータおよびセルソータ
EP2671065B1 (en) 2011-02-04 2019-07-10 Cytonome/ST, LLC Particle sorting apparatus and method
JP5765022B2 (ja) * 2011-03-31 2015-08-19 ソニー株式会社 微小粒子分析装置及び微小粒子分析方法
EP2724144B1 (en) * 2011-08-25 2018-04-11 Sony Corporation Characterization of motion-related error in a stream of moving micro-entities
EP3511694A1 (en) 2012-03-30 2019-07-17 Sony Corporation Microparticle sorting device and method for controlling position in microparticle sorting device
JP5924077B2 (ja) 2012-03-30 2016-05-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法
WO2013145836A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 マイクロチップ型光学測定装置及び該装置における光学位置調整方法
JP5994337B2 (ja) 2012-03-30 2016-09-21 ソニー株式会社 微小粒子分取装置及びディレイタイム決定方法
WO2013145905A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 微小粒子分取装置及び該装置における流体ストリーム最適化方法
WO2014013802A1 (ja) 2012-07-18 2014-01-23 ソニー株式会社 微小粒子分取装置、微小粒子分取用マイクロチップ及び微小粒子分取方法
US9669403B2 (en) 2012-07-25 2017-06-06 Sony Corporation Microparticle measurement device and liquid delivery method in microparticle measurement device
JP2014062822A (ja) 2012-09-21 2014-04-10 Sony Corp 微小粒子分析装置及び微小粒子分析方法
JP6065527B2 (ja) 2012-11-08 2017-01-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
JP6304034B2 (ja) 2013-01-28 2018-04-04 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
EP2955512B1 (en) 2013-02-08 2018-10-24 Sony Corporation Microparticle analyzing device and microparticle analyzing system
EP3035030B1 (en) 2013-10-16 2019-07-10 Sony Corporation Particle fractionation device, particle fractionation method, and program
JP6136843B2 (ja) 2013-10-17 2017-05-31 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
US10309892B2 (en) 2014-02-13 2019-06-04 Sony Corporation Particle sorting device, particle sorting method, program, and particle sorting system
JP6657625B2 (ja) 2014-09-05 2020-03-04 ソニー株式会社 液滴分取装置、液滴分取方法及びプログラム
JP6729597B2 (ja) 2015-10-19 2020-07-22 ソニー株式会社 画像処理装置、微小粒子分取装置及び画像処理方法
US10591400B2 (en) 2018-03-29 2020-03-17 Sony Corporation Micro particle analyzer and micro particle analysis method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004257756A (ja) * 2003-02-24 2004-09-16 Nippon Koden Corp フローセル位置決め方法およびフローセル位置調整可能なフローサイトメータ
JP2006242849A (ja) * 2005-03-04 2006-09-14 Mitsui Eng & Shipbuild Co Ltd 試料液流の位置制御方法および装置
JP2010286292A (ja) * 2009-06-10 2010-12-24 Sony Corp 微小粒子測定装置
JP4805417B1 (ja) * 2010-03-31 2011-11-02 古河電気工業株式会社 光情報解析装置及び光情報解析方法
JP2012047464A (ja) * 2010-08-24 2012-03-08 Sony Corp 微小粒子測定装置及び光軸補正方法

Also Published As

Publication number Publication date
JP2016191715A (ja) 2016-11-10
US10180676B2 (en) 2019-01-15
CN104204766A (zh) 2014-12-10
JP2018059943A (ja) 2018-04-12
US9915935B2 (en) 2018-03-13
US20150057787A1 (en) 2015-02-26
JP6597762B2 (ja) 2019-10-30
WO2013145836A1 (ja) 2013-10-03
US20180143609A1 (en) 2018-05-24
US10859996B2 (en) 2020-12-08
JPWO2013145836A1 (ja) 2015-12-10
US20190171179A1 (en) 2019-06-06
JP6256537B2 (ja) 2018-01-10

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