CN104147424A - Traditional Chinese medicine for treating bronchial asthma - Google Patents
Traditional Chinese medicine for treating bronchial asthma Download PDFInfo
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- CN104147424A CN104147424A CN201410423482.1A CN201410423482A CN104147424A CN 104147424 A CN104147424 A CN 104147424A CN 201410423482 A CN201410423482 A CN 201410423482A CN 104147424 A CN104147424 A CN 104147424A
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Abstract
The invention relates to a traditional Chinese medicine for treating bronchial asthma. The traditional Chinese medicine is prepared from following raw material medicines comprising, by weight, 8 parts of inula japonica, 10 parts of bamboo shavings, 9 parts of cynanchum glaucescens, 6 parts of aster tataricus, 13 parts of asparagus cochinchinensis and 9 parts of semen raphani. A clinical experiment proves that the traditional Chinese medicine can treat the bronchial asthma safely and efficiently.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of bronchial asthma.
Background technology
Bronchial asthma is to participate in chronic airway inflammation illness by various kinds of cell (as eosinophilic granulocyte, mastocyte, T lymphocyte, neutrophilic granulocyte, human airway epithelial cells etc.) and cellular component.This chronic inflammatory disease causes the generation of airway hyperreactivity, conventionally there is extensively changeable reversible airflow limitation, and causing repeatedly the symptoms such as the panting of outbreak, out of breath, uncomfortable in chest or cough, be everlasting night and (or) outbreak in morning, most of patients can spontaneous remissions or are alleviated through treatment.Clinical manifestation is that the symptoms such as uncomfortable in chest, the asthma of outbreak repeatedly and dyspnea, cough appear in typical bronchial asthma.Before outbreak, often having the premonitory symptoms such as nasal obstruction, sneeze, ophthalmic pruritus, can there is severe dyspnea, hypoxemia in outbreak severe patient in the short time.Sometimes cough is only symptom (cough variant asthma).In the outbreak of night or morning with to increase the weight of be one of feature of asthma.Symptoms of asthma can be shown effect in several minutes.During outbreak, occur that two lungs are dispersed in, fill the air the expiratory phase wheezing sound of distribution, expiratory phase extends, and air-breathing, expiratory phase all has dry rale sometimes.During serious attack, can occur that respiratory murmur is low, wheezing sound disappears, and is called clinically " static lung ", is indicating that the state of an illness is critical, there will be at any time respiratory arrest.Asthmatic patient can be without any sings and symptoms when not showing effect.
Any age of primary disease all can fall ill, but multiple with child and middle and aged women.The primary disease course of disease is long and outbreak randomness is strong, and patient's life security is caused to very large threat.
Bronchial asthma is a kind of polygenic inheritance disease that has obvious family to assemble tendency, and its generation had not only been subject to inherited genetic factors but also had been subject to the impact of environmental factors, and western medicine has expansion bronchus medicine: β at present
2receptor stimulating agent, theophylline class, anti-inflammatory drug: glucocorticoid, leukotrienes regulator, sodium cromoglicate and Buddhist nun's polyacid sodium, anti-lgE monoclonal antibody, antihistamine drug etc., but its therapeutic effect is all of short duration and side effect is larger.
Primary disease belongs to the traditional Chinese medical science " heavy breathing disease " category according to its clinical manifestation, similar with " cough with asthma ", " asthma ", " pulmonary distension " etc.
Medical material present Research involved in the present invention is as follows:
Herba Inulae [source] this product is feverfew Flos Inulae, Inula britannica and inula lineariifolia.The 9-10 month gathers, and dries.[nature and flavor] are salty, temperature.[return through] returns spleen, large intestine channel.[function cures mainly] dispersing wind and cold, the drink that reduces phlegm, detumescence poison, wind-damp dispelling.Main cough due to wind and cold, latent fluid-retention phlegm dyspnea; Distending pain in the hypochondrium; Can pyogenic infections from tumour or sore; Rheumatalgia.[usage and dosage] 3～9g.
Caulis Bambusae In Taenia [source] this product is the intermediate layer that the stem stalk of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, blue or green pole bamboo, major part allusion quotation bamboo etc. goes crust to scrape.Cut down the Hsinchu of current growth winter, remove branch and leaf, the section of being sawn into, scrapes off outer Pericarpium Citri Reticulatae Viride, then intermediate layer is spread to threadly, spreads and dries.[nature and flavor] are sweet, are slightly cold.[return through] returns spleen, stomach, gallbladder meridian.[function cures mainly] removing heat-phlegm, relieves restlessness and prevents vomiting, antiabortive removing heat from blood.Main cough due to lung-heat, dysphoria with smothery sensation palpitation with fear, gastric heat is vomitted oh; Pregnancy reactions, frequent fetal movement; Spit blood, epistaxis, hematuria, metrorrhagia.[usage and dosage] 5 ~ 10g.
Rhizoma Cynanchi Stauntonii [source] this product is the root and rhizome of dicotyledon medicine asclepiadaceae plant rhizoma et radix cynanchi stauntoni or leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii.Take Herb after autumn, root and rhizome is adopted down, clean, dry or dry.[nature and flavor] are pungent, sweet, tepor.[return through] returns lung meridian.[function cures mainly] eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Main smelting lung qi is stopped up the cough with copious phlegm of reality, dyspnea due to adverseness of QI; Gastralgia, youngster's infantile malnutrition; Traumatic injury.[usage and dosage] 3 ~ 10g.
Radix Asteris [source] this product is root and the rhizome of feverfew Radix Asteris.After aerial parts is withered, excavate root, remove dead leaf, radicula is weaved into plait shape, shine to absolutely dry.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung meridian.[function cures mainly] nourishing the lung to keep the adverse QI downward, preventing phlegm from forming and stopping coughing.Main cough, deficiency of the lung chronic cough, consumptive lung disease lung abscess; Cough vomiting bloody pus; Dysuria.[usage and dosage] 4.5 ~ 10g.
Radix Asparagi [source] this product is the tuber of liliaceous plant Radix Asparagi.Gather, prescind viticula, lifted root, removes earth, with decocting in water or steam to rhagades of the skin, pulls out in clear water, peels off while hot crust, dries or stifling with sulfur.[nature and flavor] are sweet, bitter, cold.[return through] returns lung, kidney channel.[function cures mainly] is nourshing Yin and drynsessmoistening prescription, lung heat clearing pathogenic fire reducing.Main cough caused by dryness-heat, deficiency of YIN chronic cough; Consumption of YIN caused by febrile disease, interior-heat is quenched one's thirst; Dryness of the intestine constipation; Laryngopharynx swelling and pain.[usage and dosage] 6 ~ 15g.[attention] deficiency and coldness is had loose bowels and cough due to wind and cold person prohibits clothes.
Semen Raphani [source] this product is the mature seed of crucifer Radix Raphani (Raphanus sativus L).The 5-8 month, has the abundant maturation of fruit to gather and dries, and lays seed, removes impurity, puts the storage of dry place.[nature and flavor] are pungent, sweet, flat.[return through] returns spleen, stomach, lung, large intestine channel.[function cures mainly] dyspepsia and intestinal stasis relieving, lowering the adverse-rising QI to resolve phlegm.Main stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy after dysentery; Cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest.[usage and dosage] 5 ~ 10g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of bronchial asthma, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing bronchial asthma.
In order to achieve the above object, the present invention is by the following technical solutions:
A Chinese medicine that is used for the treatment of bronchial asthma, is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Herba Inulae, 10 parts of Caulis Bambusae In Taenia, 9 parts of Rhizoma Cynanchi Stauntoniis, 6 parts of Radix Asteriss, 13 parts of Radix Asparagi, 9 parts of Semen Raphanis.
Inventor thinks that bronchial asthma is due to retained phlegm volt lung, meet inducement or sense heresy draw tactile so that stagnation of phlegm air flue impairment of purifying and descending function of the lung, paroxysmal rale asthma illness due to the twin urgency of air flue.Treatment should be take warming and recuperating the kidney-YANG, nourishing YIN to lower pathogenic fire, dispersing the stagnated live-QI to relieve the stagnation of QI as basic, therefore assembly is our.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects outpatient service and Bronchial Asthmas 107 examples of being in hospital in October, 2010 ~ 2013 altogether between year June, be divided at random treatment group 55 examples and matched group 52 examples, treatment group man 26 examples, female's 29 examples, 3～65 years old age, 41 years old mean age, the course of disease 1～12 year; Matched group man 27 examples, female's 25 examples, 6～60 years old age, 47 years old mean age, the course of disease 1～15 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
According to < < prevention and control of bronchial asthma guide > > (respirology branch of Chinese Medical Association asthma group revision, 2008) diagnostic criteria: 1) repeatedly outbreak pant, out of breath, uncomfortable in chest or cough, many with to contact allergen, cold air, physics, chemical irritation and viral upper respiratory tract infection, motion etc. relevant; 2) when outbreak is at two lung audibles and be dispersed in or diffusivity, take expiratory phase as main wheezing sound; 3) above-mentioned symptom and sign can be alleviated or spontaneous remission through treatment; 4) except other diseases causedly pant, out of breath, uncomfortable in chest and cough; 5) its atypical clinical manifestations person, should at least possess following 1 test positive: brinchial provocation test or motion activated test are positive; The positive FEV1 of Bronchodilation Test increases >=12%, and FEV1 increases absolute value >=200ml; Peak expiratory flow (PEF) day interior (or 2 weeks) aberration rate >=20%.Above-mentionedly meet front four persons or rear two persons can make a definite diagnosis primary disease.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times.4 weeks courses for the treatment of.
The oral GUILONG KECHUANNING JIAONANG of matched group, takes according to its description.4 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: the symptom of panting and pulmonary's wheezing sound disappear or not enough slight person.
Effective: the symptom of panting and pulmonary's wheezing sound are clearly better (+++ →+), FEV1 or PEFR increment are more than 30%.
Effective: the symptom of panting and pulmonary's wheezing sound take a favorable turn (+++ → ++ or ++ →+) FEV1 or PEFR increment 10%～30%.
Invalid: FEV1 or PEFR increment are less than 10%.
3.2 therapeutic outcomes are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 55 | 19 | 22 | 9 | 5 | 90.91% | 0 |
| Matched group | 52 | 9 | 12 | 17 | 14 | 73.08% | 0 |
Visible, the medicine that the present invention makes can safe and effective treatment bronchial asthma, has promotional value.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 8 grams of Herba Inulae, 10 grams of Caulis Bambusae In Taenia, 9 grams of Rhizoma Cynanchi Stauntoniis, 6 grams of Radix Asteriss, 13 grams of Radix Asparagi, 9 grams of Semen Raphanis; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of bronchial asthma.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 8 grams of Herba Inulae, 10 grams of Caulis Bambusae In Taenia, 9 grams of Rhizoma Cynanchi Stauntoniis, 6 grams of Radix Asteriss, 13 grams of Radix Asparagi, 9 grams of Semen Raphanis; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of bronchial asthma.Oral, take once every day.
Specific embodiment 3
Take: 8 grams of Herba Inulae, 10 grams of Caulis Bambusae In Taenia, 9 grams of Rhizoma Cynanchi Stauntoniis, 6 grams of Radix Asteriss, 13 grams of Radix Asparagi, 9 grams of Semen Raphanis; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of bronchial asthma.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. a Chinese medicine that is used for the treatment of bronchial asthma, is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Herba Inulae, 10 parts of Caulis Bambusae In Taenia, 9 parts of Rhizoma Cynanchi Stauntoniis, 6 parts of Radix Asteriss, 13 parts of Radix Asparagi, 9 parts of Semen Raphanis.
2. the Chinese medicine that is used for the treatment of bronchial asthma as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Herba Inulae, 10 parts of Caulis Bambusae In Taenia, 9 parts of Rhizoma Cynanchi Stauntoniis, 6 parts of Radix Asteriss, 13 parts of Radix Asparagi, 9 parts of Semen Raphanis; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. the Chinese medicine that is used for the treatment of bronchial asthma as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Herba Inulae, 10 parts of Caulis Bambusae In Taenia, 9 parts of Rhizoma Cynanchi Stauntoniis, 6 parts of Radix Asteriss, 13 parts of Radix Asparagi, 9 parts of Semen Raphanis; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packing, obtains powder; Above-mentioned part all refers to weight portion.
4. the Chinese medicine that is used for the treatment of bronchial asthma as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Herba Inulae, 10 parts of Caulis Bambusae In Taenia, 9 parts of Rhizoma Cynanchi Stauntoniis, 6 parts of Radix Asteriss, 13 parts of Radix Asparagi, 9 parts of Semen Raphanis; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, obtain capsule; Above-mentioned part all refers to weight portion.
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| CN201410423482.1A CN104147424A (en) | 2014-08-26 | 2014-08-26 | Traditional Chinese medicine for treating bronchial asthma |
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| CN201410423482.1A CN104147424A (en) | 2014-08-26 | 2014-08-26 | Traditional Chinese medicine for treating bronchial asthma |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587262A (en) * | 2015-02-02 | 2015-05-06 | 李志� | Traditional Chinese medicine for treatment of bronchial asthma |
| CN104688805A (en) * | 2015-04-02 | 2015-06-10 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating bronchial asthma |
| CN105641577A (en) * | 2015-12-23 | 2016-06-08 | 夏京奎 | Traditional Chinese medicine for treating infantile bronchial asthma |
| CN105708955A (en) * | 2016-04-13 | 2016-06-29 | 刘海强 | Medicine for treating chronic bronchitis |
| CN106334056A (en) * | 2016-08-24 | 2017-01-18 | 刘成良 | Traditional Chinese medicine preparation for treating bronchial asthma in children |
-
2014
- 2014-08-26 CN CN201410423482.1A patent/CN104147424A/en active Pending
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587262A (en) * | 2015-02-02 | 2015-05-06 | 李志� | Traditional Chinese medicine for treatment of bronchial asthma |
| CN104688805A (en) * | 2015-04-02 | 2015-06-10 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating bronchial asthma |
| CN105641577A (en) * | 2015-12-23 | 2016-06-08 | 夏京奎 | Traditional Chinese medicine for treating infantile bronchial asthma |
| CN105708955A (en) * | 2016-04-13 | 2016-06-29 | 刘海强 | Medicine for treating chronic bronchitis |
| CN106334056A (en) * | 2016-08-24 | 2017-01-18 | 刘成良 | Traditional Chinese medicine preparation for treating bronchial asthma in children |
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Application publication date: 20141119 |
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