CN104688805A - Traditional Chinese medicine for treating bronchial asthma - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating bronchial asthma. The traditional Chinese medicine is prepared by raw herbal materials which comprise, by weight, 20 parts of radix astragali, 10 parts of radix codonopsis, 10 parts of atractylodes macrocephala koidz, 6 parts of divaricate saposhnikovia roots, 6 parts of geckoes, 15 parts of stalactite and 10 parts of bombyx batryticatus. Clinical experiments show that the traditional Chinese medicine can safely and effectively treat bronchial asthma.

Description

A kind of Chinese medicine being used for the treatment of bronchial asthma

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of bronchial asthma.

Background technology

Bronchial asthma is commonly encountered diseases clinically and frequently-occurring disease.Western medical treatment is with antiallergic, remove airway spasm, it is main for controlling inflammation, and coordinates the application of the glucocorticoid of whole body or local, at asthma in acute attack stage, especially status asthmaticus, its effect is comparatively obvious, and single asthma is repeated relapsing disease, prolonged application Western medicine bronchial spasmolytic agent has certain side effect, Bronchial Asthma Treated by TCM, in consolidate curative effect, reduces recurrence, and part is removed the aspects such as hormone even completely and had comparatively significantly advantage.The most common symptom of bronchial asthma is: very difficult during expiration, and have cough, the symptom such as to cough up phlegm, can hear when checking pulmonary and cry sound like whistling " wheezing sound ".Etc. main clinic symptoms.

Medical material present Research involved in the present invention is as follows:

The Radix Astragali [another name] continuous stilbene, the continuous Radix Astragali.[source] this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Spring, Qiu Erji excavate, and removing fibrous root and root head, dry.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".

Gecko [another name] is many in, celestial toad, a red-spotted lizard Serpentis, moral to Gecko, Gecko, hold, stone tooth.[source] this product is the dry body of Gekkonidae animal Gecko.The whole year all can catch, removing internal organs, wipes clean, struts with bamboo chip, makes all flat straight, cold drying.[nature and flavor] are salty, flat.[return through] returns lung, kidney channel.[function cures mainly] invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, supporing yang benefit essence.For dyspnea due to deficiency tachypnea, chronic cough hemoptysis, impotence and seminal emission.[usage and dosage] takes orally: decoct soup, 3 ~ 6g.[attention] affection of exogenous wind-cold is breathed heavily to cough and is avoided clothes.[extracts] " China's book on Chinese herbal medicine ".

Radix Codonopsis [another name] eastern party, platform party, the Lushui River party, mouth party.The dry root that [source] this product is Campanulaceae Radix Codonopsis, element spends Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) or radix codonpsis tangshen.Autumn excavates, and cleans, dries.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.[usage and dosage] takes orally: decoct soup, 9-30g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[extracts] " China's book on Chinese herbal medicine ".

Radix Saposhnikoviae [another name] copper rues, fennel rues, fennel grass, Rhizoma Cibotii, gate of a village root, hundred roaches, screen, wind meat.[source] this product is the dry root of umbelliferae Saposhnikovia divaricata.Spring, Qiu Erji excavate the root not taking out scape plant, and removing fibrous root and silt, dry.[nature and flavor] acrid, sweet, warm.[return through] returns bladder, liver, spleen channel.[function cures mainly] inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] blood deficiency convulsion is anxious or have a headache not because ailment said due to cold or exposure person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

The Rhizoma Atractylodis Macrocephalae [another name] Rhizoma Atractylodis Macrocephalae, winter art, Zhejiang art, kind art.[source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Excavate when withered and yellow, the upper leaf of inferior leads in winter becomes fragile, removing silt, dries or dries, then remove fibrous root.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] deficiency of YIN is yearningly dry, and stagnation of QI feeling of distension and oppression person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

Bombyx Batryticatus [another name] Bombyx Batryticatus, Bombyx Batryticatus, flying worm.[source] this product is that the larva in Bombycidae insecticide silkworm 4 ~ 5 age infects (or artificial vaccination) muscardine and lethal larva dry body.Produce more than spring, autumn, the silkworm died of illness by infection muscardine is dry.[nature and flavor] are salty, pungent, flat.[return through] returns liver, lung, stomach warp.[function cures mainly] expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Bal(n)phyllia sp. [another name] radix curcumae, white silk Radix Curcumae.The oak Corallium Japonicum Kishinouye that [source] sets Corallidae for marine products coelenterate is used as medicine with calcium carbonate skeleton.The whole year can gather, and knock-off Plumbum preparatium of mixing is divided and got bar.[nature and flavor] are sweet, temperature.[return through] returns kidney, lung meridian.[function cures mainly] tonifying the lung, tonifying YANG, lactogenesis.For pulmonary tuberculosis cough asthma, spit blood, sexual impotence, weakness of the waist and knees, the diseases such as agalactia.[usage and dosage] takes orally: decoct soup, 1 ~ 5g.[extracts] " national Chinese herbal medicine compilation ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of bronchial asthma, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing bronchial asthma.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of Chinese medicine being used for the treatment of the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bal(n)phyllia sp. 15 parts, Bombyx Batryticatus 10 parts, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bal(n)phyllia sp. 15 parts, Bombyx Batryticatus 10 parts

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and Bronchial Asthmas 70 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 35 example and matched group 35 example at random, treatment group man 17 example, female 18 example, the course of disease 1 ~ 11 year, 21 ~ 55 years old age, 42 years old mean age; Matched group man 19 example, the course of disease 1 ~ 12 year, female 16 example, 20 ~ 55 years old age, 45 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national bronchial asthma clinical speciality: (1), dyspnea: after following premonitory symptom closely, occur uncomfortable in chest, the urgent even sensation of asphyxia of chest, sensation Cuba chest is seemingly by scheelite is oppressed, dyspnea is there is after about 10-15 minute, and with the wheezing sound that sharp and rounded sounds are adjusted.

(2), cough, cough up phlegm: the tendency phase often causes cough because bronchial mucosa is irritated, is first dry cough without phlegm, varying degree.Often alleviate to cough during stage of attack, turn to pant.(3), chest pain: if asthma attack is heavier, time remaining person more of a specified duration can have chest pain, may be overtired relevant with respiratory muscle.When merging pneumothorax, serious chest pain can be there is suddenly.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 2 times.1 month course for the treatment of.

Matched group mouth inhales fluticasone propionate (salmaterol, fluticasone), and each 1 inhales, and every day, 2 mouths were inhaled, 1 month course for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

With integration method evaluation curative effect, point system by the Syndrome Scale quantitative criteria of bronchial asthma, by light, in, severe 3,6,9 points respectively.By tcm syndrome efficacy assessment standard.

Clinic control: Clinical symptom and sign disappears or substantially disappears, syndrome integral reduces more than 95%;

Effective: Clinical symptom and sign obviously improves, syndrome integral reduces more than 70% and lower than 95%;

Effective: clinical symptoms take a favorable turn, syndrome integral reduces more than 30% and lower than 70%;

Invalid: Clinical symptom and sign is not improved, syndrome integral reduces lower than 30%.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Group	n	Clinic control	Effective	Effectively	Invalid	Total effective rate (%)	Serious adverse reaction example
								Treatment group	35	13	12	8	2	94.28%	0
Matched group	35	8	8	10	9	74.28%	0

Visible, the medicine that the present invention obtains can safe and effective treatment bronchial asthma, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Specific embodiment 1

Take: the Radix Astragali 20 grams, Radix Codonopsis 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 6 grams, Gecko 6 grams, Bal(n)phyllia sp. 15 grams, Bombyx Batryticatus 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of bronchial asthma.Oral, every bu is taken for twice sooner or later.

Specific embodiment 2

Take: the Radix Astragali 20 grams, Radix Codonopsis 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 6 grams, Gecko 6 grams, Bal(n)phyllia sp. 15 grams, Bombyx Batryticatus 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of bronchial asthma.Oral, every bu is taken for twice sooner or later.

Specific embodiment 3

Take: the Radix Astragali 20 grams, Radix Codonopsis 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 6 grams, Gecko 6 grams, Bal(n)phyllia sp. 15 grams, Bombyx Batryticatus 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of bronchial asthma.Oral, every bu is taken for twice sooner or later.

Claims (4)

1. be used for the treatment of a Chinese medicine for bronchial asthma, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bombyx Batryticatus 10 parts.

2., as claimed in claim 1 for the Chinese medicine of bronchial asthma, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bombyx Batryticatus 10 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. be used for the treatment of the Chinese medicine of bronchial asthma as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bombyx Batryticatus 10 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. be used for the treatment of the Chinese medicine of bronchial asthma as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Radix Codonopsis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 6 parts, Gecko 6 parts, Bombyx Batryticatus 10 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.