CN104771699A - Medicine for treating children tic disorder and preparation method of medicine - Google Patents
Medicine for treating children tic disorder and preparation method of medicine Download PDFInfo
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Abstract
The invention discloses a medicine for treating a children tic disorder. The medicine is characterized by being prepared from the following raw materials by weight: 10-20g of raw dens draconis, 10-20g of selfheal, 15-30g of uncaria, 10-20g of mint, 10-20g of scrophularia ningpoensis, 10-30g of fructus forsythia, 10-30g of thunbery fritillary bulb, 10-20g of tortoise plastron, 10-30g of gastrodia elata, 10-20g of curcuma aromatic, 5-10g of platycodon grandiflorum, 10-30g of lilium brownii, 10-30g of white muscardine silkworm, 10-20g of dandelion, 5-10g of manyleaf paris rhizome, 20-30g of semen ziziphi spinosae and 10-20g of pawpaw. Due to the formula and the preparation method disclosed by the invention, the medicine is capable of clearing away heat and toxic materials, expelling phlegm to arrest coughing, tranquilizing and allaying excitement, nourishing blood, tonifying the heart, promoting qi to activate blood, soothing the liver to subside interior wind, and nourishing yin for suppressing hyperactive yang.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine for the treatment of child tic disorder and preparation method thereof.
Background technology
Tic disorder be onset in child or adolescence, with involuntary, repeatedly, the motion twitch at one or more position fast and/or sounding are twitched is one group of syndrome of principal character.Chinese medicine claims primary disease to be " chronic infantile convulsion ", thinks diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, wind-dryness impairment of YIN, YIN-fluid being insufficient, the moon sun not processed, the kidney failing to nourish the liver, and muscle arteries and veins loses supports, then restless flesh is taken out; Water is wet is detained, and is gathered into expectorant, and fire folder expectorant superinverse, discomfort in the throat, the sound of " uttering a sound or a word ", then appear " uttering a sound or a word " between larynx, in lung gold abnormality.This sick obstinate, recurrent exerbation, is still difficult miscellaneous diseases in the world at present.Doctor trained in Western medicine mainly controls symptom by tiapride, haloperidol, but side effect is large, and relapse rate is high, cures the symptoms, not the disease, very unfavorable to children's torso health.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of child tic disorder of one [a1].
Another object of the present invention is to provide a kind of preparation method for the treatment of the medicine of child tic disorder.
For achieving the above object, the technical solution used in the present invention is: a kind of medicine for the treatment of child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 10-20g, Spica Prunellae 10-20g, Ramulus Uncariae Cum Uncis 15-30g, Herba Menthae 10-20g, Radix Scrophulariae 10-20g, Fructus Forsythiae 10-30g, Bulbus Fritillariae Thunbergii 10-30g, Carapax et Plastrum Testudinis 10-20g, Rhizoma Gastrodiae 10-30g, Radix Curcumae 10-20g, Radix Platycodonis 5-10g, Bulbus Lilii 10-30g, Bombyx Batryticatus 10-30g, Herba Taraxaci 10-20g, Rhizoma Paridis 5-10g, Semen Ziziphi Spinosae 20-30 g, Fructus Chaenomelis 10-20 g.
Treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 15-18g, Spica Prunellae 13-18g, Ramulus Uncariae Cum Uncis 23-28g, Herba Menthae 12-18g, Radix Scrophulariae 10-15g, Fructus Forsythiae 15-28g, Bulbus Fritillariae Thunbergii 14-18g, Carapax et Plastrum Testudinis 12-18g, Rhizoma Gastrodiae 12-18g, Radix Curcumae 10-15g, Radix Platycodonis 7-10g, Bulbus Lilii 15-30g, Bombyx Batryticatus 10-20g, Herba Taraxaci 10-20g, Rhizoma Paridis 5-8g, Semen Ziziphi Spinosae 18-28 g, Fructus Chaenomelis 11-19 g.
Treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 10g, Spica Prunellae 10g, Ramulus Uncariae Cum Uncis 20g, Herba Menthae 10g, Radix Scrophulariae 10g, Fructus Forsythiae 10g, Bulbus Fritillariae Thunbergii 10g, Carapax et Plastrum Testudinis 10g, Rhizoma Gastrodiae 10g, Radix Curcumae 10g, Radix Platycodonis 5g, Bulbus Lilii 10g, Bombyx Batryticatus 10g, Herba Taraxaci 10g, Rhizoma Paridis 5g, Semen Ziziphi Spinosae 20 g, Fructus Chaenomelis 10 g.
Treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 20g, Spica Prunellae 20g, Ramulus Uncariae Cum Uncis 30g, Herba Menthae 20g, Radix Scrophulariae 20g, Fructus Forsythiae 30g, Bulbus Fritillariae Thunbergii 30g, Carapax et Plastrum Testudinis 20g, Rhizoma Gastrodiae 30g, Radix Curcumae 20g, Radix Platycodonis 10g, Bulbus Lilii 30g, Bombyx Batryticatus 30g, Herba Taraxaci 20g, Rhizoma Paridis 10g, Semen Ziziphi Spinosae 30 g, Fructus Chaenomelis 20 g.
Treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 18g, Spica Prunellae 15g, Ramulus Uncariae Cum Uncis 24g, Herba Menthae 12g, Radix Scrophulariae 10g, Fructus Forsythiae 24g, Bulbus Fritillariae Thunbergii 15g, Carapax et Plastrum Testudinis 15g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 15g, Herba Taraxaci 20g, Rhizoma Paridis 6g, Semen Ziziphi Spinosae 25g, Fructus Chaenomelis 15g.
Treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 20g, Ramulus Uncariae Cum Uncis 15g, Herba Menthae 13g, Fructus Forsythiae 20g, Carapax et Plastrum Testudinis 16g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 10g, Herba Taraxaci 15g, Rhizoma Paridis 9g.
Treat a medicine for child tic disorder, it is characterized in that described pharmaceutical dosage form is decoction.
Treat a preparation method for the medicine of child tic disorder, it is characterized in that: take above-mentioned each crude drug by weight ratio, mixing, add water 800-1200ml, soak after 50-80 minutes, boil 20min, little fire is continuous decocts 8-15 minutes, cooling, filters, obtains decoction.
Treat a preparation method for the medicine of child tic disorder, it is characterized in that: take above-mentioned each crude drug by weight ratio, mixing, add water 1000ml, soaks after 60 minutes, boil 20min, and little fire is continuous decocts 10 minutes, cooling, filters, obtains decoction.
Dens Draconis puckery is cool in nature, has tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating effect, and Spica Prunellae bitter in the mouth is cold in nature, has effect of liver heat removing, eliminating stagnation, diuresis.Ramulus Uncariae Cum Uncis sweet in the mouth cold in nature, has endogenous wind stopping relieving convulsion, removing heat from the liver, effect of suppressing the hyperactive liver sun.Herba Menthae acrid in the mouth is cool in nature, has relieving sore-throat by clearing away heat, and rash is detoxified, effect of dispersing the stagnated live-QI to relieve the stagnation of QI.Radix Scrophulariae bitter in the mouth is cold in nature, has effect of clearing away heat and cooling blood, eliminating fire and detoxication, enriching yin and nourishing kidney.Fructus Forsythiae bitter in the mouth cold nature, has dispelling wind and heat pathogens, heat-clearing and toxic substances removing, effect of mass dissipating and swelling eliminating.Bulbus Fritillariae Thunbergii bitter in the mouth is cold in nature, has expelling phlegm for arresting cough, vanishing sputum and dispelling knot, effect of antalgic and sedative.Carapax et Plastrum Testudinis taste brackishness is slightly cold, and has nourishing kidney YANG hyperactivity suppressing, replenishing kidney and strengthening bone, the effect of reinforcing the heart of nourishing blood.Rhizoma Gastrodiae sweet in the mouth is put down, and has suppressing the hyperactive liver to relieve the wind syndrome, wind-expelling pain-stopping, effect of promoting flow of QI and blood.Radix Curcumae acrid in the mouth is cold in nature, has promoting QI circulation for relieving depression, and clear away heart-fire removing heat from blood, effect of depressed liver-energy dispersing and function of gallbladder promoting.Radix Platycodonis bitter in the mouth is put down, and has lung qi dispersing sore-throat relieving, the effect of evacuation of pus of eliminating the phlegm.Bulbus Lilii cold nature is put down, and has nourishing the lung to arrest cough, effect of the stomach invigorating of reason spleen, dampness removing removing food stagnancy, mind tranquilizing and the heart calming.Bombyx Batryticatus acrid in the mouth, has and expellings wind and relieving convulsion, effect of dissipating phlegm and resolving masses.Herba Taraxaci sugariness is bitter, has effect of heat-clearing and toxic substances removing, removing heat from blood, diuresis.Rhizoma Paridis bitter in the mouth is slightly cold, and has heat-clearing and toxic substances removing, effect of cool liver arresting convulsion.
Because this disease is chronic disease, need adhere to for a long time taking medicine, general one day one be secondary, takes 2-4 month, rear according to symptomatic condition change into 2 days one secondary, take the 3-5 month, then according to concrete symptom change 3 days one secondary, drug withdrawal gradually later.
Advantageous effect of the present invention is: due to this formula of the present invention and preparation method, can heat-clearing and toxic substances removing, expelling phlegm for arresting cough, tranquillizing and allaying excitement, reinforcing the heart of nourishing blood, promoting flow of QI and blood, suppressing the hyperactive liver to relieve the wind syndrome, nourishing YIN for suppressing the hyperactive YANG, carries out Comprehensive Treatment for tic disorder, we's treatment treatment child tic disorder 100 example, cure 85 examples, symptom obviously alleviates 15 examples, therapeutic effect is remarkable, and effective percentage is up to more than 98%, and side effect is little, focus on adjustment children physique, there is very high promotional value.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described:
All cases all derives from pharmacy's medical expert's consultation and woman protects Out-patient Department case in June ,-2014 in June, 2013, treatment by Chinese herbs group 50 example, wherein male 38 example, women 12 example; Year mean age (10.20 ~ 4.50); Average course of disease (1.20 ~ 3.50) year.Western medicine group 30 example, male 22 example, women 8 example; Year mean age (9.50 ~ 4.20); Average course of disease (2.90 ~ 1.50) year.Between two groups, age, sex, the course of disease are through statistics inspection, and P>0.05, has comparability.
Criterion of therapeutical effect: recovery from illness: transference cure after treatment in 3-12 month, 6 months without recidivist.Effective: transference cure or alleviate after treatment in 3-12 month, is subject to inducement and still has outbreak after drug withdrawal.Invalid: the symptom person of being not improved after treatment in 3 months.
Therapeutic outcome:
Group follows up a case by regular visits to number clinical recovery enabledisable
Experimental group 50 38 84
Matched group 30 15 96
P<0.O1 with this group before treatment; Treatment group with compare P>0.05 after treatment of control group there is comparability.
Experimental group effective percentage 92% as can be seen from the above table, matched group effective percentage 80%, and in matched group, have 10 examples to occur tiapride the extrapyramidal symptoms because of Long-term Oral, as cathisophobiaed, acute dystonia, motion can not and tremble, and affects greatly the studying and living of child.And treatment by Chinese herbs group periodic detection hepatic and renal function, no abnormality seen.
Embodiment 1: Dens Draconis 10g, Spica Prunellae 10g, Ramulus Uncariae Cum Uncis 20g, Herba Menthae 10g, Radix Scrophulariae 10g, Fructus Forsythiae 10g, Bulbus Fritillariae Thunbergii 10g, Carapax et Plastrum Testudinis 10g, Rhizoma Gastrodiae 10g, Radix Curcumae 10g, Radix Platycodonis 5g, Bulbus Lilii 10g, Bombyx Batryticatus 10g, Herba Taraxaci 10g, Rhizoma Paridis 5g, Semen Ziziphi Spinosae 20 g, Fructus Chaenomelis 10 g.
Embodiment 2: Dens Draconis 20g, Spica Prunellae 20g, Ramulus Uncariae Cum Uncis 30g, Herba Menthae 20g, Radix Scrophulariae 20g, Fructus Forsythiae 30g, Bulbus Fritillariae Thunbergii 30g, Carapax et Plastrum Testudinis 20g, Rhizoma Gastrodiae 30g, Radix Curcumae 20g, Radix Platycodonis 10g, Bulbus Lilii 30g, Bombyx Batryticatus 30g, Herba Taraxaci 20g, Rhizoma Paridis 10g, Semen Ziziphi Spinosae 30 g, Fructus Chaenomelis 20 g.
Embodiment 3: Dens Draconis 18g, Spica Prunellae 15g, Ramulus Uncariae Cum Uncis 24g, Herba Menthae 12g, Radix Scrophulariae 10g, Fructus Forsythiae 24g, Bulbus Fritillariae Thunbergii 15g, Carapax et Plastrum Testudinis 15g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 15g, Herba Taraxaci 20g, Rhizoma Paridis 6g, Semen Ziziphi Spinosae 25g, Fructus Chaenomelis 15g.
Embodiment 4: Dens Draconis 20g, Ramulus Uncariae Cum Uncis 15g, Herba Menthae 13g, Fructus Forsythiae 20g, Carapax et Plastrum Testudinis 16g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 10g, Herba Taraxaci 15g, Rhizoma Paridis 9g.
Treat a preparation method for the medicine of child tic disorder, it is characterized in that: take above-mentioned each crude drug by weight ratio, mixing, add water 1000ml, soaks after 60 minutes, boil 20min, and little fire is continuous decocts 10 minutes, cooling, filters, obtains decoction.
[A2]
Case 1:
Patient female 6 years old, occurred nictation before 1 year, squeeze eyebrow, contracting nose, during beginning, number of times is few, and the head of a family does not give attention, does not give any treatment.About blink after 3 months, squeeze eyebrow, contracting nose number of times increases, before medical to this February engender regular to blink, squeeze eyebrow, contracting nose, facial muscle are twitched, shrug, independently do not send " uttering a sound or a word " sound in larynx, absent minded, can not attentively pay attention to the class, school grade declines, often because of exacerbation of symptoms during psychentonia.Once did electroencephalogram, nuclear magnetic resonance check in outer court, and be showed no exception, give clothes " haloperidol " and treat more than March, the state of an illness alleviates to some extent.Time medical the above-mentioned action of infant still time send out, being irritable and irascible, poor appetite, complexion is slightly yellow, and god is tired, and two is just normal, red tip of the tongue, yellow and thin fur, stringy and thready pulse.Card belongs to insufficiency of the spleen liver-yang hyperactivity, liver-wind stirring up internally.Treated 30 doses with the party, examine the head of a family on April 27 two and tell and twitch number of times after infant is taken medicine and obviously reduce, amplitude of twitching reduces, and food of receiving increases, and spirit takes a turn for the better, no more side effects, continuous with former side 30 doses.On May 25 three examined, and the head of a family tells the various twitch symptom of favour youngster and substantially disappears, and occasionally had nictation, contracting nose, continued and added and subtracted more than 30 agent with consolidate curative effect with former side, recover.In in January, 2015 call-on back by phone, the head of a family tells and has no recurrence, in school grade.
Case 2: patient man 9 years old, is criticized appearance in latter second day because of long-time object for appreciation computer by the head of a family and continues to go ophthalmology to go to a doctor in one week, say it is not ophthalmic diseases, allow and loosen nictation, all right after a time.But continue remaining disappearance nictation in March and occur action of dehiscing, go to Xuzhou children's hospital to go to a doctor, be diagnosed as Gilles de la Tourette's syndrome, give tiapride and inosine treatment, because worrying side effect drug withdrawal after oral greatly 2 weeks, examine in January, 2013, time medical, patient size is more fat, pale tongue is dark, and the micro-Huang of thin fur is greasy, thready and rolling pulse.Give we treatment, examined 17 days two February after oral 30 doses, state symptom and slightly alleviate, then according to symptom plus-minus the party, take 60 doses of aftermentioned symptoms and obviously alleviate.Examine on April 21 three and change two days pairs and continue to take 30 doses, the four diagnostic methods on June 23 are stated to be had symptom to change 3 days pairs to take 30 doses once in a while, and JIUYUE 29 5 examines to state does not have symptom substantially, advises drug withdrawal gradually, only opens about 10 doses.In June, 2014 call-on back by phone, the head of a family tells and has no recurrence, and school grade is medium.
Embodiment recited above is only be described the preferred embodiment of the present invention; not design of the present invention and protection domain are limited; under the prerequisite not departing from design concept of the present invention; the various modification that in this area, common engineers and technicians make technical scheme of the present invention and improvement, all should fall into protection scope of the present invention.
Claims (9)
1. treat a medicine for child tic disorder, it is characterized in that being made up of following raw material: Dens Draconis 10-20g, Spica Prunellae 10-20g, Ramulus Uncariae Cum Uncis 15-30g, Herba Menthae 10-20g, Radix Scrophulariae 10-20g, Fructus Forsythiae 10-30g, Bulbus Fritillariae Thunbergii 10-30g, Carapax et Plastrum Testudinis 10-20g, Rhizoma Gastrodiae 10-30g, Radix Curcumae 10-20g, Radix Platycodonis 5-10g, Bulbus Lilii 10-30g, Bombyx Batryticatus 10-30g, Herba Taraxaci 10-20g, Rhizoma Paridis 5-10g, Semen Ziziphi Spinosae 20-30 g, Fructus Chaenomelis 10-20 g.
2. a kind of medicine for the treatment of child tic disorder according to claim 1, is characterized in that being made up of following raw material: Dens Draconis 15-18g, Spica Prunellae 13-18g, Ramulus Uncariae Cum Uncis 23-28g, Herba Menthae 12-18g, Radix Scrophulariae 10-15g, Fructus Forsythiae 15-28g, Bulbus Fritillariae Thunbergii 14-18g, Carapax et Plastrum Testudinis 12-18g, Rhizoma Gastrodiae 12-18g, Radix Curcumae 10-15g, Radix Platycodonis 7-10g, Bulbus Lilii 15-30g, Bombyx Batryticatus 10-20g, Herba Taraxaci 10-20g, Rhizoma Paridis 5-8g, Semen Ziziphi Spinosae 18-28 g, Fructus Chaenomelis 11-19 g.
3. a kind of medicine for the treatment of child tic disorder according to claim 1, is characterized in that being made up of following raw material: Dens Draconis 10g, Spica Prunellae 10g, Ramulus Uncariae Cum Uncis 20g, Herba Menthae 10g, Radix Scrophulariae 10g, Fructus Forsythiae 10g, Bulbus Fritillariae Thunbergii 10g, Carapax et Plastrum Testudinis 10g, Rhizoma Gastrodiae 10g, Radix Curcumae 10g, Radix Platycodonis 5g, Bulbus Lilii 10g, Bombyx Batryticatus 10g, Herba Taraxaci 10g, Rhizoma Paridis 5g, Semen Ziziphi Spinosae 20 g, Fructus Chaenomelis 10 g.
4. a kind of medicine for the treatment of child tic disorder according to claim 1, is characterized in that being made up of following raw material: Dens Draconis 20g, Spica Prunellae 20g, Ramulus Uncariae Cum Uncis 30g, Herba Menthae 20g, Radix Scrophulariae 20g, Fructus Forsythiae 30g, Bulbus Fritillariae Thunbergii 30g, Carapax et Plastrum Testudinis 20g, Rhizoma Gastrodiae 30g, Radix Curcumae 20g, Radix Platycodonis 10g, Bulbus Lilii 30g, Bombyx Batryticatus 30g, Herba Taraxaci 20g, Rhizoma Paridis 10g, Semen Ziziphi Spinosae 30 g, Fructus Chaenomelis 20 g.
5. a kind of medicine for the treatment of child tic disorder according to claim 1, is characterized in that being made up of following raw material: Dens Draconis 18g, Spica Prunellae 15g, Ramulus Uncariae Cum Uncis 24g, Herba Menthae 12g, Radix Scrophulariae 10g, Fructus Forsythiae 24g, Bulbus Fritillariae Thunbergii 15g, Carapax et Plastrum Testudinis 15g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 15g, Herba Taraxaci 20g, Rhizoma Paridis 6g, Semen Ziziphi Spinosae 25g, Fructus Chaenomelis 15g.
6. a kind of medicine for the treatment of child tic disorder according to claim 1, is characterized in that being made up of following raw material: Dens Draconis 20g, Ramulus Uncariae Cum Uncis 15g, Herba Menthae 13g, Fructus Forsythiae 20g, Carapax et Plastrum Testudinis 16g, Rhizoma Gastrodiae 15g, Radix Curcumae 12g, Radix Platycodonis 9g, Bulbus Lilii 20g, Bombyx Batryticatus 10g, Herba Taraxaci 15g, Rhizoma Paridis 9g.
7. a kind of medicine for the treatment of child tic disorder according to claim 1 or 2 or 3 or 4 or 5 or 6, is characterized in that described pharmaceutical dosage form is decoction.
8. a kind of preparation method for the treatment of the medicine of child tic disorder according to claim 7, it is characterized in that: take above-mentioned each crude drug by weight ratio, mixing, add water 800-1200ml, soaks after 50-80 minutes, boil 20min, little fire is continuous decocts 8-15 minutes, cooling, filters, obtains decoction.
9. a kind of preparation method for the treatment of the medicine of child tic disorder according to claim 8, is characterized in that: take above-mentioned each crude drug by weight ratio, mixing, and add water 1000ml, soak after 60 minutes, boil 20min, little fire is continuous decocts 10 minutes, cooling, filters, obtains decoction.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943858A (en) * | 2016-06-20 | 2016-09-21 | 崔孝菊 | Traditional Chinese medicine for treating chronic movement or sound production tic disorder and preparation method |
| CN112190635A (en) * | 2020-10-13 | 2021-01-08 | 天津中医药大学第一附属医院 | Cicada throat spray and application thereof |
-
2015
- 2015-04-22 CN CN201510192889.2A patent/CN104771699B/en active Active
Non-Patent Citations (2)
| Title |
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| 宋桂华: ""赵时雨教授从五脏论治小儿多发性抽动症经验介绍"", 《新中医》 * |
| 钟士元: "《脊柱相关疾病治疗学》", 31 March 2011 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943858A (en) * | 2016-06-20 | 2016-09-21 | 崔孝菊 | Traditional Chinese medicine for treating chronic movement or sound production tic disorder and preparation method |
| CN112190635A (en) * | 2020-10-13 | 2021-01-08 | 天津中医药大学第一附属医院 | Cicada throat spray and application thereof |
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