CN104771699B - It is a kind of to treat medicine of child tic disorder and preparation method thereof - Google Patents

It is a kind of to treat medicine of child tic disorder and preparation method thereof Download PDF

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CN104771699B
CN104771699B CN201510192889.2A CN201510192889A CN104771699B CN 104771699 B CN104771699 B CN 104771699B CN 201510192889 A CN201510192889 A CN 201510192889A CN 104771699 B CN104771699 B CN 104771699B
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medicine
tic disorder
batrytis
tortoiseshell
dandelion
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CN104771699A (en
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田晓云
徐欣昌
田爱红
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Abstract

A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 10 20g, the 20g of selfheal 10, the 30g of yncaria stem with hooks 15, the 20g of peppermint 10, the 20g of radix scrophulariae 10, the 30g of the capsule of weeping forsythia 10, the 30g of bulb of thunberg fritillary 10, the 20g of tortoiseshell 10, the 30g of rhizoma Gastrodiae 10, the 20g of root tuber of aromatic turmeric 10, the 10g of balloonflower root 5, the 30g of lily 10, the 30g of the larva of a silkworm with batrytis 10, the 20g of dandelion 10, flea stops 5 10g, the g of spina date seed 20 30, the g of pawpaw 10 20., can be clearing heat and detoxicating due to this formula and preparation method of the present invention, expelling phlegm and arresting coughing, tranquilizing and allaying excitement, blood-nourishing bushing, the promoting flow of qi and blood circulation is calming the liver to stop the wind, nourishing and suppressing Yang.

Description

It is a kind of to treat medicine of child tic disorder and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of treat medicine of child tic disorder and preparation method thereof.
Background technology
Tic disorder is onset in child or adolescent's period, with it is involuntary, repeatedly, quick one or more portions One group of syndrome that the motion of position is twitched and/or sounding twitch is principal character.This disease of traditional Chinese medicine is called " chronic infantile convulsion ", it is believed that outer Sense ailment said due to cold or exposure, wind-dryness impairment of yin, YIN-fluid being insufficient, cloudy sun not processed, water files to nourish wood, and tendon and vessel, which is lost, supports, then restless flesh is taken out;Water is wet to be detained, aggregation Into phlegm, fire folder phlegm superinverse, then there is " uttering a sound or a word ", the sound of " uttering a sound or a word " between larynx in discomfort in the throat, lung gold abnormality.This sick obstinate, sends out repeatedly Make, be still difficult and complicated cases in the world at present.Doctor trained in Western medicine controls symptom mainly by Tiapride, haloperole, but side effect is big, multiple Hair rate is high, cures the symptoms, not the disease, very unfavorable to children's torso health.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating child tic disorder of a kind of [a1].
It is a further object to provide a kind of preparation method for the medicine for treating child tic disorder.
To achieve the above object, the technical solution adopted by the present invention is:A kind of medicine for treating child tic disorder, it is special Levy and be to be made up of following raw materials:Raw dens draconis 10-20g, selfheal 10-20g, yncaria stem with hooks 15-30g, peppermint 10-20g, radix scrophulariae 10- 20g, capsule of weeping forsythia 10-30g, bulb of thunberg fritillary 10-30g, tortoiseshell 10-20g, rhizoma Gastrodiae 10-30g, root tuber of aromatic turmeric 10-20g, balloonflower root 5-10g, lily 10- 30g, larva of a silkworm with batrytis 10-30g, dandelion 10-20g, flea stop 5-10g, spina date seed 20-30 g, pawpaw 10-20 g.
A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 15-18g, the summer is withered Careless 13-18g, yncaria stem with hooks 23-28g, peppermint 12-18g, radix scrophulariae 10-15g, capsule of weeping forsythia 15-28g, bulb of thunberg fritillary 14-18g, tortoiseshell 12-18g, day Numb 12-18g, root tuber of aromatic turmeric 10-15g, balloonflower root 7-10g, lily 15-30g, larva of a silkworm with batrytis 10-20g, dandelion 10-20g, flea stops 5-8g, Spina date seed 18-28 g, pawpaw 11-19 g.
A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 10g, selfheal 10g, yncaria stem with hooks 20g, peppermint 10g, radix scrophulariae 10g, capsule of weeping forsythia 10g, bulb of thunberg fritillary 10g, tortoiseshell 10g, rhizoma Gastrodiae 10g, root tuber of aromatic turmeric 10g, balloonflower root 5g, hundred 10g, larva of a silkworm with batrytis 10g, dandelion 10g are closed, flea stops 5g, the g of spina date seed 20, the g of pawpaw 10.
A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 20g, selfheal 20g, yncaria stem with hooks 30g, peppermint 20g, radix scrophulariae 20g, capsule of weeping forsythia 30g, bulb of thunberg fritillary 30g, tortoiseshell 20g, rhizoma Gastrodiae 30g, root tuber of aromatic turmeric 20g, balloonflower root 10g, Lily 30g, larva of a silkworm with batrytis 30g, dandelion 20g, flea stop 10g, the g of spina date seed 30, the g of pawpaw 20.
A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 18g, selfheal 15g, yncaria stem with hooks 24g, peppermint 12g, radix scrophulariae 10g, capsule of weeping forsythia 24g, bulb of thunberg fritillary 15g, tortoiseshell 15g, rhizoma Gastrodiae 15g, root tuber of aromatic turmeric 12g, balloonflower root 9g, hundred 20g is closed, larva of a silkworm with batrytis 15g, dandelion 20g, flea stop 6g, spina date seed 25g, pawpaw 15g.
A kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 20g, yncaria stem with hooks 15g, peppermint 13g, capsule of weeping forsythia 20g, tortoiseshell 16g, rhizoma Gastrodiae 15g, root tuber of aromatic turmeric 12g, balloonflower root 9g, lily 20g, larva of a silkworm with batrytis 10g, dandelion 15g, flea stops 9g.
A kind of medicine for treating child tic disorder, it is characterised in that described pharmaceutical dosage form is decoction.
A kind of preparation method for the medicine for treating child tic disorder, it is characterised in that:Weigh by weight ratio above-mentioned each Bulk drug, mixing, add water 800-1200ml, after soaking 50-80 minutes, boils 20min, and small fire is continuous to decoct 8-15 minutes, cold But, filter, obtain decoction.
A kind of preparation method for the medicine for treating child tic disorder, it is characterised in that:Weigh by weight ratio above-mentioned each Bulk drug, mixing, add water 1000ml, after soaking 60 minutes, boils 20min, and small fire is continuous to decoct 10 minutes, cools down, and filtering obtains soup Agent.
Raw dens draconis puckery is cool in nature, calming the liver with tranquillizing the mind by relieving convulsion, the effect of restraining astringent or styptic treatment for spontaneous sweating, and selfheal bitter is cold in nature, tool There are clearing liver, dissipating bind, diuresis.Yncaria stem with hooks is cold in nature sweet, with Inflammation Zhijing, removing heat from the liver, the effect of Pinggan Yang.Peppermint is pungent It is cool in nature, with clearing heat, relieving sore-throat, promoting eruption removing toxic substances, the effect of soothing liver-qi stagnation.Radix scrophulariae bitter is cold in nature, with clearing heat and cooling blood, purging intense heat and detonicating, The effect of enriching yin and nourishing kidney.Capsule of weeping forsythia bitter cold nature, it is clearing heat and detoxicating with dispelling wind and heat from the body, the effect of mass dissipating and swelling eliminating.Bulb of thunberg fritillary bitter It is cold, with expelling phlegm and arresting coughing, vanishing sputum and dispelling knot, the effect of antalgic and sedative.Tortoiseshell taste brackishness is slightly cold, and with nourshing kidney checking exuberance of yang, kidney-nourishing is good for The effect of bone, blood-nourishing bushing.Rhizoma Gastrodiae is sweet mild-natured, with suppressing hyperactive liver for calming endogenous wind, wind-expelling pain-stopping, the effect of the promoting flow of qi and blood circulation.Root tuber of aromatic turmeric is pungent Cold in nature, with promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, the effect of soothing liver-gallbladder.Balloonflower root bitter is mild-natured, with facilitaing lung relieving sore-throat, eliminating the phlegm apocenosis The effect of.Lily cold nature is put down, with moistening the lung and relieve the cough, the effect of the stomach invigorating of reason spleen, dampness removing disperse accumulations, antitoxic heart-soothing and sedative.The larva of a silkworm with batrytis is pungent, With expelling wind and relieving convulsion, the effect of reducing phlegm and resolving masses.Dandelion property sugariness is bitter, the effect of with clearing heat and detoxicating, cool blood, diuresis.Flea stops Bitter is slightly cold, with clearing heat and detoxicating, the effect of cool liver is calmed the frightened.
Because the disease is chronic disease, medication need to be adhered to for a long time, general one day one is secondary, taken 2-4 months, after according to symptom feelings Condition is changed to 2 days one pairs, takes the 3-5 months, changes 3 days one pairs further according to specific symptom, is gradually discontinued later.
Advantages of the present invention effect is:, can be clearing heat and detoxicating due to this formula and preparation method of the present invention, eliminating the phlegm Cough-relieving, tranquilizing and allaying excitement, blood-nourishing bushing, the promoting flow of qi and blood circulation is calming the liver to stop the wind, nourishing and suppressing Yang, and complex treatment is carried out for tic disorder, this Side's treatment treatment child tic disorder 100, cures 85, symptom substantially mitigates 15, and significantly, effective percentage is up to therapeutic effect More than 98%, and Small side effects, regulation children physique is focused on, with very high promotional value.
Embodiment
With reference to specific embodiment, the invention will be further described:
All cases derive from pharmacy's medical expert's consultation and woman protects Out-patient Department case in June, -2014 in June, 2013, Chinese medicine Treatment group 50, wherein male 38, women 12;Average age (10.20 ~ 4.50) year;Average course of disease (1.20 ~ 3.50) Year.Western medicine group 30, male 22, women 8;Average age (9.50 ~ 4.20) year;Average course of disease (2.90 ~ 1.50) Year.Age, sex, the course of disease are through statistics inspection, P between two groups>0.05, with comparativity.
Criterion of therapeutical effect:Recovery from illness:Symptom disappears after treatment in 3-12 months, and 6 months without recidivist.Effectively:By 3-12 Symptom disappears or mitigated after treatment in individual month, is still had breaking-out by inducement after drug withdrawal.It is invalid:Symptom is without obvious after being treated through 3 months Improver.
Treatment results:
Group follow-up number clinical recovery enabledisable
Experimental group 50 38 84
Control group 30 15 96
P with this group before treatment<0.O1;Treatment group is compared P after being treated with control group>0.05 has comparativity.
Experimental group effective percentage 92%, control group effective percentage 80%, and have 10 in control group because long-term as can be seen from the above table Orally there are Tiapride the extrapyramidal symptoms, such as cathisophobia, acute dystonia, motion can not and be trembled, to children Studying and living affect greatly.And Chinese herbs group periodic detection hepatic and renal function, no abnormality seen.
Embodiment 1:Raw dens draconis 10g, selfheal 10g, yncaria stem with hooks 20g, peppermint 10g, radix scrophulariae 10g, capsule of weeping forsythia 10g, bulb of thunberg fritillary 10g, Tortoiseshell 10g, rhizoma Gastrodiae 10g, root tuber of aromatic turmeric 10g, balloonflower root 5g, lily 10g, larva of a silkworm with batrytis 10g, dandelion 10g, flea stop 5g, the g of spina date seed 20, The g of pawpaw 10.
Embodiment 2:Raw dens draconis 20g, selfheal 20g, yncaria stem with hooks 30g, peppermint 20g, radix scrophulariae 20g, capsule of weeping forsythia 30g, bulb of thunberg fritillary 30g, Tortoiseshell 20g, rhizoma Gastrodiae 30g, root tuber of aromatic turmeric 20g, balloonflower root 10g, lily 30g, larva of a silkworm with batrytis 30g, dandelion 20g, flea stop 10g, spina date seed 30 G, the g of pawpaw 20.
Embodiment 3:Raw dens draconis 18g, selfheal 15g, yncaria stem with hooks 24g, peppermint 12g, radix scrophulariae 10g, capsule of weeping forsythia 24g, bulb of thunberg fritillary 15g, Tortoiseshell 15g, rhizoma Gastrodiae 15g, root tuber of aromatic turmeric 12g, balloonflower root 9g, lily 20g, larva of a silkworm with batrytis 15g, dandelion 20g, flea stop 6g, spina date seed 25g, Pawpaw 15g.
Embodiment 4:Raw dens draconis 20g, yncaria stem with hooks 15g, peppermint 13g, capsule of weeping forsythia 20g, tortoiseshell 16g, rhizoma Gastrodiae 15g, root tuber of aromatic turmeric 12g, tangerine Obstruct 9g, lily 20g, larva of a silkworm with batrytis 10g, dandelion 15g, flea stops 9g.
A kind of preparation method for the medicine for treating child tic disorder, it is characterised in that:Weigh by weight ratio above-mentioned each Bulk drug, mixing, add water 1000ml, after soaking 60 minutes, boils 20min, and small fire is continuous to decoct 10 minutes, cools down, and filtering obtains soup Agent.
[A2]
Case 1:
, there is blink, squeezes eyebrow, contracting nose, number of times is few during beginning, and parent does not give attention, does not give and appointing in patient female 6 years old before 1 year What is treated.Blinked after about 3 months, squeeze eyebrow, the increase of contracting nose number of times, gone to a doctor to this engender within first 2 months it is regular blink, Eyebrow, contracting nose, facial muscles is squeezed to twitch, shrug, not sending " uttering a sound or a word " sound independently in larynx, it is absent minded, it is impossible to attentively to pay attention to the class, School grade declines, exacerbation of symptoms when often because of stress.Once electroencephalogram, nuclear magnetic resonance check are done in outer court, exception is showed no, Give clothes " haloperole " treatment more than March, the state of an illness has mitigated.When medical the above-mentioned action of infant still when send out, being irritable and irascible is received Difference, complexion is slightly yellow, and god is tired, and two is just normal, the thin Huang of red tip of tongue, tongue, small and wiry pulse.Card category is insufficiency of the spleen liver-yang hyperactivity, liver wind agitation.Give the party 30 doses for the treatment of, examines parent on April 27 two and tells that twitching number of times after infant medication significantly reduces, and twitches amplitude reduction, receive and eat increase, essence God takes a turn for the better, no more side effects, continues with 30 doses of original side.On May 25 three examined, and parent tells that the various symptoms of twitching of favour youngster disappear substantially, even There are blink, contracting nose, continue and add and subtract more than 30 agent with original side to consolidate curative effect, recover.In in January, 2015 call-on back by phone, parent, which tells, to be had no On in recurrence, school grade.
Case 2:Patient man 9 years old, occurs blink for second day after being criticized because of long-time object for appreciation computer by parent and continues to remove an eye in Section goes to a doctor, and says it is not ophthalmology disease, allows and loosen, all right after a time.But continue remaining blink disappearance in March and action of dehiscing occur, Go to Xuzhou children's hospital to go to a doctor, be diagnosed as Gilles de la Tourette's syndrome, give Tiapride and inosine treatment, after worrying that side effect is big oral 2 weeks It is discontinued, is examined in January, 2013, patient size is more fat when going to a doctor, tongue nature is light dark, and the thin micro- yellow greasy of tongue, arteries and veins is fine and smooth.We are given to control Treat, oral 30 doses were examined after 17 days 2 months two, were stated symptom and were slightly mitigated, the party is added and subtracted according to symptom then, 60 doses of aftermentioned symptoms are taken bright It is aobvious to mitigate.Examine on April 21 three and change two days pairs and continue to take 30 doses, the four methods of diagnosis on June 23, which are stated once in a while, to be had symptom to change 3 days pairs to take 30 doses, September 29 5, which is examined, to be stated substantially without symptom, it is proposed that is gradually discontinued, is only issued 10 doses or so.In June, 2014 call-on back by phone, family Length tells no relapse, and school grade is medium.
The above-described embodiments are merely illustrative of preferred embodiments of the present invention, not to the structure of the present invention Think and protection domain is defined, on the premise of design concept of the present invention is not departed from, ordinary skill technical staff in this area The all variations and modifications made to technical scheme, all should fall into protection scope of the present invention.

Claims (8)

1. a kind of medicine for treating child tic disorder, it is characterised in that be made up of following raw materials:Raw dens draconis 10-20g, selfheal 10-20g, yncaria stem with hooks 15-30g, peppermint 10-20g, radix scrophulariae 10-20g, capsule of weeping forsythia 10-30g, bulb of thunberg fritillary 10-30g, tortoiseshell 10-20g, rhizoma Gastrodiae 10-30g, root tuber of aromatic turmeric 10-20g, balloonflower root 5-10g, lily 10-30g, larva of a silkworm with batrytis 10-30g, dandelion 10-20g, flea stops 5-10g, acid Jujube kernel 20-30 g, pawpaw 10-20 g.
2. a kind of medicine for treating child tic disorder according to claim 1, it is characterised in that be made up of following raw materials: Raw dens draconis 15-18g, selfheal 13-18g, yncaria stem with hooks 23-28g, peppermint 12-18g, radix scrophulariae 10-15g, capsule of weeping forsythia 15-28g, bulb of thunberg fritillary 14- 18g, tortoiseshell 12-18g, rhizoma Gastrodiae 12-18g, root tuber of aromatic turmeric 10-15g, balloonflower root 7-10g, lily 15-30g, larva of a silkworm with batrytis 10-20g, dandelion 10-20g, flea stops 5-8g, spina date seed 18-28 g, pawpaw 11-19 g.
3. a kind of medicine for treating child tic disorder according to claim 1, it is characterised in that be made up of following raw materials: Raw dens draconis 10g, selfheal 10g, yncaria stem with hooks 20g, peppermint 10g, radix scrophulariae 10g, capsule of weeping forsythia 10g, bulb of thunberg fritillary 10g, tortoiseshell 10g, rhizoma Gastrodiae 10g, Root tuber of aromatic turmeric 10g, balloonflower root 5g, lily 10g, larva of a silkworm with batrytis 10g, dandelion 10g, flea stop 5g, the g of spina date seed 20, the g of pawpaw 10.
4. a kind of medicine for treating child tic disorder according to claim 1, it is characterised in that be made up of following raw materials: Raw dens draconis 20g, selfheal 20g, yncaria stem with hooks 30g, peppermint 20g, radix scrophulariae 20g, capsule of weeping forsythia 30g, bulb of thunberg fritillary 30g, tortoiseshell 20g, rhizoma Gastrodiae 30g, Root tuber of aromatic turmeric 20g, balloonflower root 10g, lily 30g, larva of a silkworm with batrytis 30g, dandelion 20g, flea stop 10g, the g of spina date seed 30, the g of pawpaw 20.
5. a kind of medicine for treating child tic disorder according to claim 1, it is characterised in that be made up of following raw materials: Raw dens draconis 18g, selfheal 15g, yncaria stem with hooks 24g, peppermint 12g, radix scrophulariae 10g, capsule of weeping forsythia 24g, bulb of thunberg fritillary 15g, tortoiseshell 15g, rhizoma Gastrodiae 15g, Root tuber of aromatic turmeric 12g, balloonflower root 9g, lily 20g, larva of a silkworm with batrytis 15g, dandelion 20g, flea stop 6g, spina date seed 25g, pawpaw 15g.
6. a kind of medicine for treating child tic disorder according to claim 1 or 2 or 3 or 4 or 5, it is characterised in that institute The pharmaceutical dosage form stated is decoction.
7. a kind of preparation method of medicine for treating child tic disorder according to claim 6, it is characterised in that:By weight Amount proportioning weighs above-mentioned each bulk drug, mixes, add water 800-1200ml, after soaking 50-80 minutes, boils 20min, and small fire continues Decoct 8-15 minutes, cool down, filtering obtains decoction.
8. a kind of preparation method of medicine for treating child tic disorder according to claim 7, it is characterised in that:By weight Amount proportioning weighs above-mentioned each bulk drug, mixes, add water 1000ml, after soaking 60 minutes, boils 20min, and small fire is continuous to decoct 10 minutes, Cooling, filtering, obtains decoction.
CN201510192889.2A 2015-04-22 2015-04-22 It is a kind of to treat medicine of child tic disorder and preparation method thereof Active CN104771699B (en)

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CN105943858A (en) * 2016-06-20 2016-09-21 崔孝菊 Traditional Chinese medicine for treating chronic movement or sound production tic disorder and preparation method
CN112190635A (en) * 2020-10-13 2021-01-08 天津中医药大学第一附属医院 Cicada throat spray and application thereof

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