CN104146240A - 一种降糖降脂保健组合物及其制备方法 - Google Patents
一种降糖降脂保健组合物及其制备方法 Download PDFInfo
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- CN104146240A CN104146240A CN201310703056.9A CN201310703056A CN104146240A CN 104146240 A CN104146240 A CN 104146240A CN 201310703056 A CN201310703056 A CN 201310703056A CN 104146240 A CN104146240 A CN 104146240A
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Abstract
本发明公开了一种降糖降脂保健组合物及其制备方法，属于保健食品加工技术领域。该保健组合物主要由以下重量份数的原料组成：玉竹20～30份、竹叶黄酮5～8份、黄精20～30份、天花粉20～30份、葛根20～30份、山楂20～30份、大黄20～30份、薏苡仁20～30份、木瓜20～30份、蜂花粉15～20份、夏枯草20～30份、苦瓜20～30份。本发明根据中医药食同源理念，将玉竹、黄精、葛根、山楂、大黄、薏苡仁、木瓜共7种药食同源物品与竹叶黄酮、天花粉、蜂花粉、夏枯草、苦瓜复配，具有降糖降脂、增强机体免疫力等功效；其粉剂、颗粒剂或咀嚼片剂的制备方法简单，成本低，且便于携带，饮用更加方便。
Description
技术领域
本发明具体涉及一种降糖降脂保健组合物，以及该保健组合物的制备方法，属于保健食品加工技术领域。
背景技术
随着现代社会生活节奏的加快，尤其是一些办公室白领男女面临的亚健康状态日益加重。亚健康是一种临界状态，处于亚健康状态的人没有明确的疾病，但是会出现精神活力和适应能力下降等状况，如果这种状态不能得到及时纠正，非常容易引起身心疾病，身体上常出现如高血压、高血脂等病症。
中医素有药食同源之说，药食同源的理论认为：许多食物既是食物也是药物，食物和药物一样同样能够防治疾病。在古代原始社会中，人们在寻找食物的过程中发现了各种食物和药物的性味和功效，认识到许多食物可以药用，许多药物也可以食用，两者之间很难严格区分。这就是“药食同源”理论的基础，也是食物疗法的基础。
中国专利（申请号：200910068865.0）公开了一种基于治未病和药食同源理论的防治糖尿病的食疗制剂，由乌梅、玉竹、山药、枸杞子、山楂和鲜芦根组成，具有滋阴健脾、活血清热之功。专利（申请号：200810114658.X）公开了一种五色降糖果蔬茶饮料，由山楂、山药、山茱萸、酸枣仁、何首乌等28种原料制成，具有消渴降糖、提高机体免疫力等功效。然而，目前市面上出现的保健制剂口味较为单一、营养成分含量低，降糖降脂功效欠佳，且携带不方便，难以满足人们需求。
发明内容
本发明的目的是提供一种降糖降脂保健组合物。
同时，本发明还提供一种降糖降脂保健组合物的制备方法。
为了实现以上目的，本发明所采用的技术方案是：
一种降糖降脂保健组合物，主要由以下重量份数的原料组成：玉竹20～30份、竹叶黄酮5～8份、黄精20～30份、天花粉20～30份、葛根20～30份、山楂20～30份、大黄20～30份、薏苡仁20～30份、木瓜20～30份、蜂花粉15～20份、夏枯草20～30份、苦瓜20～30份。
一种降糖降脂保健组合物，还包括以下重量份数的辅料：乙基麦芽酚3～3.5份、苯甲酸钠0.3～0.5份、丁香油0.3～0.5份、维生素E8～10份、糖醇0.1～0.2份、糊精30～45份。
所述的糖醇如甘露糖醇、麦芽糖醇、乳糖醇、木糖醇等。
优选的，葛根选用粉甘葛，木瓜选用宣木瓜（产自安徽宣城），蜂花粉选用玉米花粉、松花粉中的一种或其任意组合。
各原料功效简述如下：
玉竹：为百合科黄精属植物玉竹的根茎；含有多糖类如玉竹黏多糖、挂多糖等，甾族化合物如黄精螺甾醇POa、虎杖苷等，糖苷类如β-谷甾醇-3-O-β-D-吡喃葡萄糖苷、铃兰苦苷、铃兰苷、槲皮素苷等多种活性成分；性味甘、平，归肺、胃经；能滋阴润肺、养胃生津；主治燥咳、劳嗽、热病阴伤、咽干口渴、消渴、阴虚外感、头昏眩晕、筋脉挛痛等；现代药理学证明玉竹具有降血糖、降血脂、抗肿瘤、抗突变等作用。
竹叶黄酮（竹叶抗氧化剂）：是从竹叶中提取出来的具有生理活性的生物黄酮，是一种高效的生物抗氧化剂，也是人体必须的营养素；其有效成分包括黄酮类（如碳苷黄酮）、内酯类（如羟基香豆素及糖苷）和酚类化合物（如肉桂酸衍生物，包括绿原酸、咖啡酸和阿魏酸等），是一组复杂的而又具有相互协同增效作用的混合物；具有平和的风味及口感，无药味、苦味和刺激性气味，水溶性好，品质稳定，能有效抵御酸解、热解和酶解；具有高效的抗脂质氧化性，兼具抗菌、抑菌、除臭、增香作用，能保护心脑血管、调节血脂、降低血液粘稠度，增强免疫功能、抗疲劳等。
黄精：为百合科黄精属植物黄精、多花黄精和滇黄精的根茎；含有呋甾烯醇型皂苷、螺甾烯醇型皂苷、黄精多糖等多种活性成分；黄精性味甘，平，归脾、肺、肾经；能养阴润肺，补脾益气，滋肾填精；主治阴虚劳嗽，肺燥咳嗽，脾虚乏力，食少口干，消渴，肾亏腰膝酸软，耳鸣目暗，须发早白，体虚羸瘦，风癞癣疾等；现代药理学证明黄精对心血管系统、血糖、免疫功能和环核苷酸含量产生影响，还能降血脂、延缓衰老，提高学习能力和实现记忆再现的能力。
天花粉：为葫芦科栝楼属植物栝楼及中华栝楼的根；含有蛋白质如天花粉蛋白、α-天花粉蛋白、天花粉蛋白-ZG等，氨基酸及肽类如α-羟甲基丝氨酸、天冬氨酸、苏氨酸、丝氨酸、谷氨酸、瓜氨酸、甘氨酸、缬氨酸、酪氨酸等，糖类如核糖、木糖、阿拉伯糖、葡萄糖、半乳糖、栝楼根多糖A-E等，脂肪酸类如泻醇酸、棕榈酸等，甾醇类以及具有抗癌和免疫活性的多糖（由葡萄糖、半乳糖、果糖、甘露糖、木糖和小量蛋白质组成），其他成分如α和β-苦瓜素、葫芦苦素等多种活性成分；性味甘、微苦、微寒，归肺、胃经；能清热生津、润肺化痰、消肿排脓；主治热病口渴、消渴多饮、肺热燥咳、疮疡肿毒等；现代药理学证明天花粉具有抗癌、抗艾滋病病毒等作用。
葛根：为豆科葛属植物野葛或甘葛藤的块根；含有黄酮类如大豆苷元、大豆苷、葛根素等，葛根酚、葛根苷A-B、染料木素、羽扇烯酮、β-谷甾醇、二十二烷酸、二十四烷酸、尿囊素、5-甲基海因、槐花二醇、广东相思子三醇、大豆皂醇A-B、葛根皂醇C、A和葛根皂醇B甲酯等多种活性成分；性味甘、辛、平，归脾、胃经；能解肌发表、生津止渴、升阳止泻；主治外感发热、头项强痛、麻疹初起、疹出不畅、温病口渴、消渴病、泻痢、痢疾等；现代药理学证明葛根对心血管系统、脑血管系统、糖尿病及其并发症、免疫系统有积极作用，还具有抗骨质疏松、益智、抗肿瘤、降血脂、抗氧化、解酒及雌激素样作用等。
葛粉为豆科葛属植物野葛、甘葛藤的块根经水磨而澄取的淀粉，性味甘、寒，归胃经，能解热除烦、生津止渴，主治烦热、口渴、醉酒、喉痹、疮疖等。《中药大辞典》中葛粉的制备方法为：将葛根洗净，用破碎机将其破碎成2cm以下的小块，用磨碎机磨成粉浆，边磨边加水，块根与水的比例为1:2；过滤除渣，纯化，于烘房中50℃左右的温度下烘干，再过100目筛即得。
山楂：为蔷薇科山楂属植物山里红、山楂的成熟果实；含有黄酮类如左旋表儿茶素、槲皮素、牡荆素等，酸类如绿原酸、枸橼酸等，脂肪酸如亚油酸、棕榈酸等多种活性成分；性味酸、甘、微温，归脾、胃、肝经；能消食健胃，行气散瘀；主治饮食积滞，脘腹胀痛，泄泻痢疾，血瘀痛经、经闭，产后腹痛、恶露不尽，疝气或睾丸肿痛，高血脂症等；现代药理学证明山楂具有促消化、降压降脂、抗氧化、防癌、保护心脑血管系统和增强免疫系统功能等作用。
大黄（川军）：为蓼科大黄属植物掌叶大黄、唐古特大黄或药用大黄的根茎及根；含有游离蒽醌类如大黄酸、芦荟大黄素、大黄素等，综合蒽醌类如掌叶大黄素、大黄素甲醚-8-葡萄糖苷等，还含有双蒽醌类如掌叶大黄二蒽醌A、B、C，番泻苷A、B、C、D等，二苯乙烯苷类等多种活性成分；性味苦，寒，归胃、大肠、肝、脾经；能攻积滞，清湿热，泻火，凉血，祛瘀，解毒；主治实积便秘、热结胸痞，湿热泻痢、黄疸、淋病、水肿腹满、小便不利，目赤、咽喉肿痛、口舌生疮、胃热呕吐，吐血、咯血、衄血、便血、尿血，蓄血、经闭、产后瘀滞腹痛、癥瘕积聚、跌打损伤，热毒痈疡、丹毒、烫伤等；现代药理学证明大黄具有利胆、保肝、抗胃和十二指肠溃疡、抗病原微生物（细菌、真菌及病毒）、抗肿瘤、抗炎、止血、降脂等作用。
薏苡仁（薏仁）：为禾本科薏苡属植物薏苡的种仁；含有薏苡仁酯如三酰甘油、二酰甘油、一酰甘油、甾醇酯、游离脂肪酸等，其中游离脂肪酸包括亚油酸、棕榈酸、硬脂酸、顺-8-十八烯酸等，还含有葡萄糖、酸性多糖CA-1、CA-2及薏苡多糖A-C，挥发油如己醛、己酸、辛酸、棕榈酸乙酯、亚油酸甲酯、香草醛及亚油酸乙酯等多种活性成分；性味甘、淡、微寒，归脾、胃、肺经；能利湿健脾、舒筋除痹、清热排脓；主治水肿、脚气、小便淋沥、湿温病、泄泻、带下、风湿痹痛、筋脉拘挛、肺痈、肠痈等；现代药理学证明薏苡仁具有抗肿瘤、抑制骨骼肌收缩、镇痛、解热、抗炎、降血糖、增强免疫等作用。
木瓜：为蔷薇科木瓜属植物皱皮木瓜的果实；含有三萜类成分如3-O-乙酰熊果酸、3-O-乙酰坡模醇酸、白桦脂酸、齐墩果酸，脂肪酸类如苹果酸、酒石酸、枸橼酸、4-甲氧基苯甲酸、琥珀酸、苯甲酸等，还含有10-二十九烷醇、β-谷甾醇、β-谷甾醇-6-D-葡萄糖苷；性味酸、温，归肝、脾、胃经；能舒筋活络、和胃化湿；主治风湿痹痛、肢体酸重、筋脉拘挛、吐泻转筋、水肿、痢疾等；现代药理学证明木瓜具有保肝、抗菌等作用。
蜂花粉：是指蜜蜂采蜜时带回的花粉团，在蜂巢内经过储藏、发酵后形成的花粉，其主要食疗成分为蛋白质、氨基酸（22种）、维生素（14种）、蜂花粉素、微量元素（30余种）、活性酶、黄酮类化合物、脂类、核酸、芸苔素、植酸等；能够防治心脑血管病、降血脂、调节神经系统、促进睡眠、调节胃肠系统功能、促进消化、治疗习惯性便秘、延缓衰老、促进造血功能等，还有明显的防癌抑癌和保肝护肝、防治贫血、糖尿病、抗疲劳等功能，另外还具有美容功效，全面调节人体内分泌系统的平衡，由里及表，从根本上改善皮肤细胞活力，增强皮肤的代谢机能，防止面部色素沉着、皮肤粗糙、衰老，使皮肤保持湿润、洁白，有光泽，富有弹性。蜂花粉的制备方法为：取蜂花粉调节水分含量为20～25%，铺平至厚度为2～4cm，在36～38℃下自然发酵48～72小时，期间每隔8～12小时翻动一次；再于50℃下干燥、粉碎即得。
蜂花粉的种类主要依据粉源植物来区分，如茶花粉、油菜花粉等，优选如下：
玉米花粉：能促进脾脏、骨骼、淋巴结和胸腺免疫器官的发育，增强免疫细胞活性，提高机体对抗细菌、病毒的能力，并有抗辐射、抗癌作用；其中玉米花粉中含有丰富的维生素B族物质，其中维生素B1能刺激消化酶的产生，帮助消化，维生素B6、矿物质和蛋氨酸等能治疗顽固性便秘和泻痢；还含有天然抗生素及促进生长的物质，可抑制沙门氏菌等的繁殖，修复胃肠损伤；同时还含有大量抗氧化成分如胡萝卜素、微量元素硒等，能抑制体内脂质、蛋白质的过氧化反应，延缓衰老；矿物质锌、镁等对青春痘及其他皮肤疾病有较好治愈功效；另外，玉米花粉能增进肝细胞活性，促进肝脏解毒功能，供应充足的钾、氨基酸和酶，扼止肾小球破裂，修补损伤肾脏组织及胰脏组织，促进胰岛素分泌，减轻糖尿病症状，还能增强血管壁弹性，降低血压等。
松花粉：为松科植物马尾松、油松或其同属植物的花粉；性味甘、平、无毒；含有蛋白质、脂肪、糖类、微生物、微量元素、黄酮、酶、脂肪酸及辅酶等200余种营养成分及生物活性物质；能祛风益气、收湿、止血；主治头旋眩晕、中虚胃疼、久痢、诸疮湿烂、创伤止血；现代药理学证明松花粉具有延缓衰老、美容、治疗胃肠功能紊乱、护肝、养护心血管、治疗便秘、抗疲劳等作用。
夏枯草：为唇形科夏枯草属植物夏枯草或长冠夏枯草的果穗；含有三萜类如熊果酸、齐墩果酸、β-香树酯醇等，还含有夏枯草多糖、三萜皂苷类及黄酮类（如槲皮素、芸香苷、金丝桃苷等），以及咖啡酸、左旋樟脑和右旋小茴香酮等多种活性成分；性味苦、辛、寒，归肝、胆经；能清肝明目、散结解毒；主治目赤羞明、目珠疼痛、头痛眩晕、耳鸣、急慢性肝炎、高血压病等；现代药理学证明夏枯草具有抗炎、免疫抑制、降血糖、抗菌、抗病毒等作用。
苦瓜：为葫芦科苦瓜属植物苦瓜的果实；含有苦瓜混苷如β-谷甾醇-β-D-葡萄糖苷、5,25-豆甾二烯醇-3-葡萄糖苷，还含有5-羟色胺、谷氨酸、丙氨酸、β-丙氨酸、苯丙氨酸、脯氨酸等多种氨基酸及半乳糖醛酸、果胶，类脂中脂肪酸如棕榈酸、硬脂酸、油酸、亚油酸、亚麻酸、桐酸等多种活性成分；性味苦、寒，归心、脾、肺经；能祛暑涤热、明目、解毒；主治暑热烦渴、消渴、赤眼疼痛、痢疾、疮痈肿毒等；现代药理学证明苦瓜具有降血糖、抗癌、抗病毒、抗菌等作用。
一种降糖降脂保健组合物，可以采用常规方法制备成粉剂、颗粒剂、口含片、咀嚼片等剂型，其中赋形剂的选择视剂型而定，可选用填充剂、防腐剂、抗氧化剂、调味剂、润湿剂等。本发明仅分别提供一种粉剂和颗粒剂的制备方法。
一种降糖降脂保健组合物的制备方法，包括以下步骤：
（1）按照重量份数准确取各原料，将玉竹、黄精分别蒸制0.5～1.5小时，干燥后粉碎制成细粉备用；
（2）取天花粉、薏苡仁、蜂花粉、夏枯草和苦瓜，干燥后分别粉碎制成细粉备用；
（3）取山楂、木瓜分别炒焦后粉碎制成细粉备用；
（4）按照质量比为（8～9）:1取大黄与黄酒，拌匀后浸润0.5～1.5小时，炒至焦黄色备用；
（5）竹叶黄酮粉碎制成细粉备用；
（6）将葛根粉碎后加水制成细粉备用；
（7）取步骤（1）-（6）的细粉，混匀后分装即得粉剂；或者取步骤（2）的夏枯草细粉、步骤（3）的山楂和木瓜细粉，加水提取后合并滤液并浓缩，在浓缩液中加入上述其他细粉料，混匀后再加入乙基麦芽酚、苯甲酸钠、丁香油、维生素E、糖醇和糊精制粒，干燥即得颗粒剂；或者将上述颗粒压片后干燥制得咀嚼片剂，咀嚼有利于胃肠道吸收，加快生理药代动力。
所述的竹叶黄酮的制备方法为：取竹叶加水提取后合并滤液，分离出竹叶黄酮。
本发明的有益效果：
本发明根据中医药食同源理念，将玉竹、黄精、葛根、山楂、大黄、薏苡仁、木瓜共7种药食同源物品与竹叶黄酮、天花粉、蜂花粉、夏枯草、苦瓜复配，具有降糖降脂、增强机体免疫力等功效。其中玉竹含有玉竹多糖、玉竹苷等活性成分，能明显降低人体血糖值，改善糖耐量功能，对葡萄糖和四氧嘧啶引起的动物模型血糖升高有明显抑制作用；竹叶黄酮能促进胰岛素再生，是防治糖尿病的主体原料之一；黄精含有降血糖活性成分，其降糖作用与抑制肝糖醇解有关；天花粉中的栝楼根多糖A、B、C、D、E能降低血糖，以栝楼根多糖A最为突出；葛根中葛根素具有降血糖作用，能对抗四氧嘧啶和肾上腺素；山楂具有护肝健胃作用，可促进饮食及降血糖、降血脂；大黄中大黄多糖可降低四氧嘧啶所致糖尿病血糖胰岛素抗性，改善糖代谢；薏苡仁由显著的降血糖、降血脂作用；木瓜具有降血糖、血脂和抗四氧嘧啶所致的糖降解作用；蜂花粉中含有人体所需的各种营养成分，营养均衡，具有增强机体免疫力、调节血脂、降血糖、延缓衰老等作用；夏枯草可明显抑制四氧嘧啶引起的小鼠血糖升高，其作用强度为100mg，相当于22.6u的胰岛素；苦瓜中含有多种苦瓜多肽，也称植物胰岛素，由166个氨基酸组成，具有降糖作用。
本发明将降糖降脂保健组合物制备成粉剂、颗粒剂或咀嚼片剂，其方法简单、易操作，成本低，适于大规模工业化生产，且便于携带，食用更加方便。
具体实施方式
下述实施例仅对本发明作进一步详细说明，但不构成对本发明的任何限制。
实施例1
本实施例中的降糖降脂保健组合物，由以下重量份数的原料组成：玉竹粉20份、竹叶黄酮8份、黄精粉20份、天花粉30份、葛根粉20份、焦山楂粉30份、熟大黄粉20份、薏苡仁粉30份、木瓜粉20份、蜂花粉20份、夏枯草粉20份、苦瓜粉30份。
本实施例中降糖降脂保健组合物的制备方法为：按照重量份数准确取各原料，混合均匀后粉碎成细粉，以10g/袋的量分装即得。注：上述粉剂均为市售商品。
实施例2
本实施例中的降糖降脂保健组合物，由以下重量份数的原料组成：玉竹23份、竹叶黄酮7份、黄精27份、天花粉27份、葛根22份、山楂22份、大黄24份、薏苡仁26份、木瓜25份、玉米花粉18份、夏枯草30份、苦瓜22份。
本实施例中降糖降脂保健组合物的制备方法，包括以下步骤：
（1）按照重量份数准确取各原料，将玉竹、黄精分别蒸制0.5小时，干燥后粉碎制成细粉备用；
（2）取天花粉、薏苡仁、蜂花粉、夏枯草和苦瓜，干燥后分别粉碎制成细粉备用；
（3）取山楂、木瓜分别炒焦后粉碎制成细粉备用；
（4）按照质量比为8:1取大黄与黄酒，拌匀后浸润0.5小时，炒至焦黄色备用；
（5）叶黄酮粉碎制成细粉备用；
（6）将葛根粉碎后加水制成细粉备用；
（7）取步骤（1）-（6）的细粉，混合均匀，以10g/袋的量分装即得。
实施例3
本实施例中的降糖降脂保健组合物，由以下重量份数的原料组成：玉竹25份、竹叶黄酮6.5份、黄精25份、天花粉25份、葛根25份、山楂25份、大黄25份、薏苡仁25份、木瓜22份、松花粉17.5份、夏枯草25份、苦瓜25份、乙基麦芽酚3.25份、苯甲酸钠0.4份、丁香油0.4份、维生素E9份、糖醇0.15份、糊精35份。
本实施例中降糖降脂保健组合物的制备方法，包括以下步骤：
（1）按照重量份数准确取各原料，将玉竹、黄精分别蒸制1小时，干燥后粉碎制成细粉备用；
（2）取天花粉、薏苡仁、蜂花粉、夏枯草和苦瓜，干燥后分别粉碎制成细粉备用；
（3）取山楂、木瓜分别炒焦后粉碎制成细粉备用；
（4）按照质量比为8.5:1取大黄与黄酒，拌匀后浸润1小时，炒至焦黄色备用；
（5）竹叶黄酮粉碎制成细粉备用；
（6）将葛根粉碎后加水制成细粉备用；
（7）取步骤（2）的夏枯草细粉、步骤（3）的山楂和木瓜细粉，加水提取后合并滤液并浓缩，在浓缩液中加入上述其他细粉料，混匀后再加入乙基麦芽酚、苯甲酸钠、丁香油、维生素E、糖醇和糊精制粒，干燥后以15g/袋的量分装即得。
上述颗粒剂在50～70℃水温下分散迅速，适于长期饮用，无任何毒副作用，如每日2～3次，每次1～2袋。
实施例4
本实施例中的降糖降脂保健组合物，由以下重量份数的原料组成：玉竹27份、竹叶黄酮6份、黄精22份、天花粉23份、葛根28份、山楂27份、大黄28份、薏苡仁23份、木瓜27份、玉米花粉16份、夏枯草22份、苦瓜28份、乙基麦芽酚3份、苯甲酸钠0.5份、丁香油0.5份、维生素E8份、糖醇0.2份、糊精45份。
本实施例中降糖降脂保健组合物的制备方法实施例3。
实施例5
本实施例中的降糖降脂保健组合物，由以下重量份数的原料组成：玉竹30份、竹叶黄酮5份、黄精30份、天花粉20份、葛根30份、山楂20份、大黄30份、薏苡仁20份、木瓜30份、蜂花粉15份、夏枯草28份、苦瓜20份、乙基麦芽酚3.5份、苯甲酸钠0.3份、丁香油0.3份、维生素E10份、糖醇0.1份、糊精30份。
本实施例中降糖降脂保健组合物的制备方法同实施例3。
案例：
1、秦某，男，56岁，经医院诊断为乙型糖尿病，久服中药症状无缓解；遂服用本发明实施例3制备的保健颗粒剂，每日3次，每次1包，连续服用30天，观察其餐后血糖值由10.1/mg/ml降至7.2/mg/ml；连续服用3个月后血糖值基本正常。
2、丁某，男，65岁，经医院诊断为乙型糖尿病，症状期每日需注射长效胰岛素1支，停药后症状出现；遂服用本发明实施例4制备的保健颗粒剂，每日2次，每次2包，连续服用3个月后可停用人工胰岛素，症状明显缓解。
3、王某，女，52岁，经医院诊断其血脂、胆固醇和血糖长期偏高；遂服用本发明实施例5制备的保健颗粒剂，每日1次，每次1包，连续服用2个月后血脂、胆固醇和血糖值均降至正常水平，久服无反复。
Claims (8)
1.一种降糖降脂保健组合物，其特征在于：主要由以下重量份数的原料组成：玉竹20～30份、竹叶黄酮5～8份、黄精20～30份、天花粉20～30份、葛根20～30份、山楂20～30份、大黄20～30份、薏苡仁20～30份、木瓜20～30份、蜂花粉15～20份、夏枯草20～30份、苦瓜20～30份。
2.根据权利要求1所述的降糖降脂保健组合物，其特征在于：还包括以下重量份数的辅料：乙基麦芽酚3～3.5份、苯甲酸钠0.3～0.5份、丁香油0.3～0.5份、维生素E8～10份、糖醇0.1～0.2份、糊精30～45份。
3.根据权利要求1或2所述的降糖降脂保健组合物，其特征在于：所述的葛根为粉甘葛。
4.根据权利要求1或2所述的降糖降脂保健组合物，其特征在于：所述的木瓜为宣木瓜。
5.根据权利要求1或2所述的降糖降脂保健组合物，其特征在于：所述的蜂花粉为玉米花粉或松花粉。
6.根据权利要求2所述的降糖降脂保健组合物，其特征在于：所述的糖醇为甘露糖醇、麦芽糖醇、乳糖醇或木糖醇。
7.一种如权利要求1所述的降糖降脂保健组合物的制备方法，其特征在于：包括以下步骤：
（1）按照重量份数准确取各原料，将玉竹、黄精分别蒸制0.5～1.5小时，干燥后粉碎制成细粉备用；
（2）取天花粉、薏苡仁、蜂花粉、夏枯草和苦瓜，干燥后分别粉碎制成细粉备用；
（3）取山楂、木瓜分别炒焦后粉碎制成细粉备用；
（4）按照质量比为（8～9）:1取大黄与黄酒，拌匀后浸润0.5～1.5小时，炒至焦黄色备用；
（5）竹叶黄酮粉碎制成细粉备用；
（6）将葛根粉碎后加水制成细粉备用；
（7）取步骤（1）-（6）的细粉，混匀后分装即得。
8.一种如权利要求2所述的降糖降脂保健组合物的制备方法，其特征在于：包括以下步骤：
（1）按照重量份数准确取各原料，将玉竹、黄精分别蒸制0.5～1.5小时，干燥后粉碎制成细粉备用；
（2）取天花粉、薏苡仁、蜂花粉、夏枯草和苦瓜，干燥后分别粉碎制成细粉备用；
（3）取山楂、木瓜分别炒焦后粉碎制成细粉备用；
（4）按照质量比为（8～9）:1取大黄与黄酒，拌匀后浸润0.5～1.5小时，炒至焦黄色备用；
（5）竹叶黄酮粉碎制成细粉备用；
（6）将葛根粉碎后加水制成细粉备用；
（7）取步骤（2）的夏枯草细粉、步骤（3）的山楂和木瓜细粉，加水提取后合并滤液并浓缩，在浓缩液中加入上述其他细粉料，混匀后再加入乙基麦芽酚、苯甲酸钠、丁香油、维生素E、糖醇和糊精制粒，干燥即得。
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105249153A (zh) * | 2015-09-30 | 2016-01-20 | 曾楚凌 | 降糖降脂植物营养活化米及其制备方法 |
| CN105876363A (zh) * | 2014-12-03 | 2016-08-24 | 仲恺农业工程学院 | 一种复合果蔬粉泡腾咀嚼片的制作方法 |
| CN107961329A (zh) * | 2017-12-24 | 2018-04-27 | 宁国平衡健康管理有限公司 | 一种降血糖的宣木瓜粉 |
| CN109303870A (zh) * | 2018-12-11 | 2019-02-05 | 武汉知本药业有限公司 | 一种可降血压和血脂的溶栓组合物及其制备方法和应用 |
| CN111700277A (zh) * | 2020-06-23 | 2020-09-25 | 江苏周春祥中医科技有限公司 | 可替代蔗糖的甜味组合物及其制备方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1742931A (zh) * | 2005-09-17 | 2006-03-08 | 张志祥 | 玉竹决明冲剂及其制备工艺 |
| CN101971983A (zh) * | 2010-09-02 | 2011-02-16 | 安吉铭鑫茶业科技有限公司 | 一种含有竹叶黄酮的油基口服乳液及其制备方法 |
| CN102919836A (zh) * | 2012-11-09 | 2013-02-13 | 刘东元 | 一种降糖、降压、降脂、通便养颜、减肥、抗疲劳保健品及其生产工艺 |
| CN103053748A (zh) * | 2012-12-31 | 2013-04-24 | 青岛华仁信息技术开发有限公司 | 一种葛根降脂降糖保健茶及其制备方法 |
-
2013
- 2013-12-17 CN CN201310703056.9A patent/CN104146240B/zh not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1742931A (zh) * | 2005-09-17 | 2006-03-08 | 张志祥 | 玉竹决明冲剂及其制备工艺 |
| CN101971983A (zh) * | 2010-09-02 | 2011-02-16 | 安吉铭鑫茶业科技有限公司 | 一种含有竹叶黄酮的油基口服乳液及其制备方法 |
| CN102919836A (zh) * | 2012-11-09 | 2013-02-13 | 刘东元 | 一种降糖、降压、降脂、通便养颜、减肥、抗疲劳保健品及其生产工艺 |
| CN103053748A (zh) * | 2012-12-31 | 2013-04-24 | 青岛华仁信息技术开发有限公司 | 一种葛根降脂降糖保健茶及其制备方法 |
Non-Patent Citations (2)
| Title |
|---|
| 李玉林 等: "影响血糖的中药", 《糖尿病（消渴病）中医诊治荟萃——全国第五次中医糖尿病学术大会论文集》 * |
| 胡桂敏等: "糖友不仅要降糖 还需养生", 《糖尿病新世界》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105876363A (zh) * | 2014-12-03 | 2016-08-24 | 仲恺农业工程学院 | 一种复合果蔬粉泡腾咀嚼片的制作方法 |
| CN105249153A (zh) * | 2015-09-30 | 2016-01-20 | 曾楚凌 | 降糖降脂植物营养活化米及其制备方法 |
| CN107961329A (zh) * | 2017-12-24 | 2018-04-27 | 宁国平衡健康管理有限公司 | 一种降血糖的宣木瓜粉 |
| CN109303870A (zh) * | 2018-12-11 | 2019-02-05 | 武汉知本药业有限公司 | 一种可降血压和血脂的溶栓组合物及其制备方法和应用 |
| CN111700277A (zh) * | 2020-06-23 | 2020-09-25 | 江苏周春祥中医科技有限公司 | 可替代蔗糖的甜味组合物及其制备方法 |
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