CN104053439B - 1-(5,6-二氯-1h-苯并[d]咪唑-2-基)-1h-吡唑-4-羧酸的葡甲胺盐制剂 - Google Patents

1-(5,6-二氯-1h-苯并[d]咪唑-2-基)-1h-吡唑-4-羧酸的葡甲胺盐制剂 Download PDF

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CN104053439B
CN104053439B CN201280052789.4A CN201280052789A CN104053439B CN 104053439 B CN104053439 B CN 104053439B CN 201280052789 A CN201280052789 A CN 201280052789A CN 104053439 B CN104053439 B CN 104053439B
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acid
vol
hif
phd
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CN104053439A (zh
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K.塞帕斯
M.C.里兹佐里奧
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Janssen Pharmaceutica NV
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
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  • Dermatology (AREA)
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  • Child & Adolescent Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201280052789.4A 2011-10-25 2012-10-25 1-(5,6-二氯-1h-苯并[d]咪唑-2-基)-1h-吡唑-4-羧酸的葡甲胺盐制剂 Active CN104053439B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610488118.2A CN106038556A (zh) 2011-10-25 2012-10-25 1‑(5,6‑二氯‑1h‑苯并[d]咪唑‑2‑基)‑1h‑吡唑‑4‑羧酸的葡甲胺盐制剂

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US201161551395P 2011-10-25 2011-10-25
US61/551,395 2011-10-25
US61/551395 2011-10-25
PCT/US2012/061847 WO2013063221A1 (en) 2011-10-25 2012-10-25 Meglumine salt formulations of 1-(5,6-dichloro-1h-benzo[d]imidazol-2-yl)-1h-pyrazole-4-carboxylic acid

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CN201610488118.2A Division CN106038556A (zh) 2011-10-25 2012-10-25 1‑(5,6‑二氯‑1h‑苯并[d]咪唑‑2‑基)‑1h‑吡唑‑4‑羧酸的葡甲胺盐制剂

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CN104053439A CN104053439A (zh) 2014-09-17
CN104053439B true CN104053439B (zh) 2016-08-24

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CN201610488118.2A Pending CN106038556A (zh) 2011-10-25 2012-10-25 1‑(5,6‑二氯‑1h‑苯并[d]咪唑‑2‑基)‑1h‑吡唑‑4‑羧酸的葡甲胺盐制剂

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US (4) US9273034B2 (enExample)
EP (3) EP3461820B1 (enExample)
JP (2) JP6122862B2 (enExample)
KR (1) KR102087020B1 (enExample)
CN (2) CN104053439B (enExample)
AU (2) AU2012328763A1 (enExample)
BR (1) BR112014009910B1 (enExample)
CA (1) CA2853455C (enExample)
CY (1) CY1123426T1 (enExample)
ES (3) ES2818977T3 (enExample)
HU (1) HUE052128T2 (enExample)
IN (1) IN2014DN03155A (enExample)
MX (2) MX368157B (enExample)
WO (1) WO2013063221A1 (enExample)

Cited By (1)

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CN106038556A (zh) * 2011-10-25 2016-10-26 詹森药业有限公司 1‑(5,6‑二氯‑1h‑苯并[d]咪唑‑2‑基)‑1h‑吡唑‑4‑羧酸的葡甲胺盐制剂

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WO2013112950A2 (en) 2012-01-25 2013-08-01 Neupharma, Inc. Certain chemical entities, compositions, and methods
EP2897618B1 (en) 2012-09-24 2021-11-17 Neupharma, Inc. Certain chemical entities, compositions, and methods
EP2916838B1 (en) 2012-11-12 2019-03-13 Neupharma, Inc. Certain chemical entities, compositions, and methods
CN104610153B (zh) * 2015-01-19 2017-02-22 沈阳中海生物技术开发有限公司 奥扎格雷葡甲胺盐及其组合物、制备方法和用途
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BR112022010388A2 (pt) 2019-11-28 2022-10-25 Nihon Nohyaku Co Ltd Composto de benzimidazol ou sal deste, agente inseticida e acaricida agrícola e hortícola que contém o referido composto e método para sua utilização
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Publication number Priority date Publication date Assignee Title
CN106038556A (zh) * 2011-10-25 2016-10-26 詹森药业有限公司 1‑(5,6‑二氯‑1h‑苯并[d]咪唑‑2‑基)‑1h‑吡唑‑4‑羧酸的葡甲胺盐制剂

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AU2017204598A1 (en) 2017-07-27
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