CN104039964A - 可调控的基因表达系统及其构建体 - Google Patents

可调控的基因表达系统及其构建体 Download PDF

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Publication number
CN104039964A
CN104039964A CN201280016692.8A CN201280016692A CN104039964A CN 104039964 A CN104039964 A CN 104039964A CN 201280016692 A CN201280016692 A CN 201280016692A CN 104039964 A CN104039964 A CN 104039964A
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Prior art keywords
seq
nucleic acid
polypeptide
acid molecule
expression
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CN201280016692.8A
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English (en)
Chinese (zh)
Inventor
R·J·特纳
V·塞尔尚
J·艾肯斯
D·霍尔兹
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Proterro Inc
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Proterro Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201280016692.8A 2011-03-25 2012-03-26 可调控的基因表达系统及其构建体 Pending CN104039964A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161467873P 2011-03-25 2011-03-25
US61/467,873 2011-03-25
PCT/US2012/030602 WO2012135137A2 (en) 2011-03-25 2012-03-26 Regulated gene expression systems and constructs thereof

Publications (1)

Publication Number Publication Date
CN104039964A true CN104039964A (zh) 2014-09-10

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CN201280016692.8A Pending CN104039964A (zh) 2011-03-25 2012-03-26 可调控的基因表达系统及其构建体

Country Status (16)

Country Link
US (1) US9506072B2 (enExample)
EP (1) EP2689017A4 (enExample)
JP (1) JP2014518611A (enExample)
KR (1) KR20140043890A (enExample)
CN (1) CN104039964A (enExample)
AU (1) AU2012236811A1 (enExample)
BR (1) BR112013024630A2 (enExample)
CA (1) CA2827774A1 (enExample)
GT (1) GT201300220A (enExample)
IL (1) IL228039A0 (enExample)
MX (1) MX2013010872A (enExample)
NI (1) NI201300094A (enExample)
PH (1) PH12013501901A1 (enExample)
SG (1) SG193356A1 (enExample)
WO (1) WO2012135137A2 (enExample)
ZA (1) ZA201306420B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105802927A (zh) * 2016-04-08 2016-07-27 暨南大学 一种6-磷酸葡萄糖脱氢酶及其编码基因和应用
CN108350474A (zh) * 2015-09-25 2018-07-31 奥地利工业生物技术中心有限公司 小分子糖基化的方法
CN111100796A (zh) * 2018-10-26 2020-05-05 中国石油化工股份有限公司 一种富含油脂的栅藻及其培养应用
CN113754728A (zh) * 2020-09-30 2021-12-07 广州派真生物技术有限公司 腺相关病毒突变体及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101407824A (zh) * 2008-11-24 2009-04-15 昆明理工大学 拟南芥细胞质型谷氨酰胺合成酶基因的植物表达载体的构建和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101765661B (zh) 2007-06-01 2014-08-06 索拉兹米公司 在微生物中生产油
US9650642B2 (en) 2008-02-08 2017-05-16 Algenol Biotech LLC Genetically modified cyanobacteria for the production of ethanol
CN107034142A (zh) 2008-11-28 2017-08-11 泰拉瑞亚控股公司 在异养型微生物中制备特制油
WO2012116345A2 (en) * 2011-02-24 2012-08-30 South Dakota State University Genetically engineered cyanobacteria

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101407824A (zh) * 2008-11-24 2009-04-15 昆明理工大学 拟南芥细胞质型谷氨酰胺合成酶基因的植物表达载体的构建和应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANTONIA HERRERO ET AL: "Nitrogen control in cyanobacteria", 《JOURNAL OF BACTERIOLOGY》 *
HSIN-HO HUANG ET AL: "Design and characterization of molecular tools for a synthetic biology approach towards developing cyanobacterial biotechnology", 《NUCLEIC ACID RESEARCH》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108350474A (zh) * 2015-09-25 2018-07-31 奥地利工业生物技术中心有限公司 小分子糖基化的方法
CN108350474B (zh) * 2015-09-25 2022-06-28 巴斯夫美容护理法国公司 小分子糖基化的方法
CN105802927A (zh) * 2016-04-08 2016-07-27 暨南大学 一种6-磷酸葡萄糖脱氢酶及其编码基因和应用
CN111100796A (zh) * 2018-10-26 2020-05-05 中国石油化工股份有限公司 一种富含油脂的栅藻及其培养应用
CN111100796B (zh) * 2018-10-26 2021-07-09 中国石油化工股份有限公司 一种富含油脂的栅藻及其培养应用
CN113754728A (zh) * 2020-09-30 2021-12-07 广州派真生物技术有限公司 腺相关病毒突变体及其应用

Also Published As

Publication number Publication date
WO2012135137A2 (en) 2012-10-04
NI201300094A (es) 2014-02-28
ZA201306420B (en) 2014-12-23
CA2827774A1 (en) 2012-10-04
SG193356A1 (en) 2013-10-30
JP2014518611A (ja) 2014-08-07
MX2013010872A (es) 2014-02-28
US9506072B2 (en) 2016-11-29
GT201300220A (es) 2015-12-01
WO2012135137A3 (en) 2014-05-08
KR20140043890A (ko) 2014-04-11
AU2012236811A1 (en) 2013-09-12
BR112013024630A2 (pt) 2019-09-24
EP2689017A4 (en) 2015-06-03
PH12013501901A1 (en) 2013-10-14
US20120244622A1 (en) 2012-09-27
IL228039A0 (en) 2013-09-30
EP2689017A2 (en) 2014-01-29

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Application publication date: 20140910