CN104027420B - A kind of fowl Chinese medicine composition preventing and treating coccidiosis and preparation method thereof - Google Patents
A kind of fowl Chinese medicine composition preventing and treating coccidiosis and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to the Chinese medicine composition of a kind of fowl with control coccidiosis, be prepared from by Radix Puerariae, the Radix Pulsatillae, Radix Sophorae Flavescentis, Rhizoma Osmundae, Herba Agrimoniae, Ramulus et Folium Dichroae febrifugae, Rhizoma Coptidis, Pericarpium Granati.This Chinese medicine composition can be oral liquid, and its preparation process is: Chinese medicine powder is broken to 30-50 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, soak 5-20 hour; (3) hydrolyzed solution is heated to 40-100 DEG C, extracts 6-10 hour; (4) excessively filter medicinal residues, the direct fill of gained liquid gets product.Chinese drug-treated group provided by the present invention effectively can prevent and treat birds Caecum Coccidiosis, little intestinal coccidiosis, can reach more than 95% to Eimeria Tenella, murder by poisoning eimeria tenella killing rate; To the coli-infection due to coccidiosis secondary, also there is obviously therapeutic effect fast.This prescription has the effect of heat-clearing and toxic substances removing, dampness, parasite killing, antidiarrheal, yang invigorating.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind of fowl Chinese medicine composition preventing and treating coccidiosis and preparation method thereof.
Background technology
Coccidiosis belongs to the disease occurred frequently in poultry cultivation process, its pathogenic source is that the coccidiosis of Eimeria colonizes in birds small intestinal or caecum mucosa, breed and cause intestinal tissue damage, the hemorrhage common protozoacide of one causing suffering from fowl, the pathogenic strength wherein colonizing in the Eimeria tenella in caecum mucosal epithelial cells is strong, the young fowl in main infringement 3 weeks ages ~ 5 week age, also known as caecum coccidiosis; Another kind is the murder by poisoning Amy Archon worm of infringement small intestinal mucosa, also known as doing little visible peristalsis visible intestinal peristalsis coccidiosis.Primary disease is that harm birds raises a kind of important parasite disease of producing.Existing market solves coccidiosis and mainly relies on the medicines such as sulfonamides, triazines, polyethers, quinolines.This type of medicine ubiquity easily produces the significant deficiency such as drug resistance, toxic and side effects are large, in addition drug dependence in recent years, has much locally occurred in the face of the situation that coccidiosis is felt simply helpless; The residual excessive problem of anticoccidial class medicine medicine is also that outlet cultivates the rather thorny difficult problem of group simultaneously.
It is low that Chinese medicine has toxic and side effects, no drug residue, the advantage of environmental protection.Therefore develop Chinese medicine coccidiostat, overcome the defect of above-mentioned chemical medicine class coccidiosis medicine, become the problem that China's poultry cultivation industry is badly in need of solving.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of good effect, no drug residue, safe and reliable fowl Chinese medicine composition.
Another technical problem that the present invention will solve is: provide a kind of fowl Chinese medicine formula of control coccidiosis.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of fowl Chinese medicine composition of control coccidiosis, be prepared from by the raw material of following mass fraction: Radix Puerariae 5-10 part, Radix Pulsatillae 10-20 part, Radix Sophorae Flavescentis 10-15 part, Rhizoma Osmundae 10-15 part, Herba Agrimoniae 10-15 part, Ramulus et Folium Dichroae febrifugae 10-15 part, Rhizoma Coptidis 10-15 part, Pericarpium Granati 10-15 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows:
Radix Puerariae 10 parts, the Radix Pulsatillae 20 parts, Radix Sophorae Flavescentis 15 parts, Rhizoma Osmundae 15 parts, Herba Agrimoniae 10 parts, Ramulus et Folium Dichroae febrifugae 10 parts, Rhizoma Coptidis 10 parts, Pericarpium Granati 10 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be oral liquid, and now the input amount of water is 100-300 part.
Another technical problem that the present invention will solve is: the preparation method providing the oral liquid formulations of above-mentioned fowl Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: the preparation method of the oral liquid formulations of said composition is: Chinese medicine powder is broken to 30-50 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, soak 5-20 hour; (3) hydrolyzed solution obtained after immersion is heated to 40 DEG C-100 DEG C, extracts 6-10 hour; (4) excessively filter medicinal residues, the direct fill of gained liquid gets product.
The advantage that the present invention has and good effect are:
(1) the present invention is according to tcm theory, scientific compatibility, remain the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and use that the effective ingredient of modern means of science and technology to wherein most of medical material carries out quantitatively, half-quantitative detection, through clinical verification determined curative effect, it is a kind of green veterinary drug of nuisanceless no drug residue.
(2) Chinese medicine ingredients that the present invention contains effectively can prevent and treat birds Caecum Coccidiosis, little intestinal coccidiosis, can reach more than 95% to Eimeria Tenella, murder by poisoning eimeria tenella killing rate; To the coli-infection due to coccidiosis secondary, also there is obviously therapeutic effect fast, as shown in table 1-1; It also avoid the teratogenesis defect that disables of chemicals simultaneously, there is heat-clearing and toxic substances removing, dampness, parasite killing, antidiarrheal, the effect of yang invigorating gas.
(3) pharmacology of each raw material of Chinese medicine of the present invention is:
Radix Puerariae: expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.
The Radix Pulsatillae: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.
Radix Sophorae Flavescentis: heat clearing and damp drying, parasite killing, diuresis.
Rhizoma Osmundae: heat-clearing and toxic substances removing, cooling blood for hemostasis, parasite killing.
Herba Agrimoniae: astringing to arrest bleeding, dysentery relieving, tonify deficiency.
Ramulus et Folium Dichroae febrifugae: expectorant, cuts dysentery.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
Pericarpium Granati: relieving diarrhea with astringents, parasite killing, astringing to arrest bleeding.
Radix Sophorae Flavescentis among formula, Rhizoma Osmundae heat-clearing and toxic substances removing, has effect of parasite killing concurrently, can kill multiple Enterozoa.The main gas rising the clear sun of taste of Radix Puerariae, and reach promoting the production of body fluid to quench thirst, the merit of antidiarrheal.Be usually used in calentura excessive thirst, the deficiency of YIN is quenched one's thirst; Diarrhea of heat type hematodiarrhoea, diarrhea due to hypofunction of the spleen, yang invigorating gas and mending is had loose bowels.The Radix Pulsatillae joins Pericarpium Granati both can relieving diarrhea with astringents, again can astringing to arrest bleeding.The band water folder blood thus quick elimination is had loose bowels, the symptom of becoming thin and going into a coma with spasm of dewatering, reduces mortality rate.Rhizoma Coptidis is the thing in large bitter Great Cold, is longer than heat clearing and damp drying, controls in damp and hot retardance burnt.Another being apt to goes taste damp-heat in the large intestine, for controlling dysentery key medicine.Herba Agrimoniae astringing to arrest bleeding joined by Ramulus et Folium Dichroae febrifugae, relieving diarrhea with astringents dysentery relieving, is the common drug of anti-dysentery.
Detailed description of the invention
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
A fowl Chinese medicine oral liquid for control coccidiosis, the parts by weight of each raw material are as follows: Radix Puerariae 10 parts, the Radix Pulsatillae 20 parts, Radix Sophorae Flavescentis 15 parts, Rhizoma Osmundae 15 parts, Herba Agrimoniae 10 parts, Ramulus et Folium Dichroae febrifugae 10 parts, Rhizoma Coptidis 10 parts, Pericarpium Granati 10 parts, 150 parts, water.Its preparation method is: Chinese medicine powder is broken to 30-50 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, soak 5-20 hour; (3) hydrolyzed solution obtained after immersion is heated to 40 DEG C-100 DEG C, extracts 6-10 hour; (4) excessively filter medicinal residues, the direct fill of gained liquid (every bottle of 250ml) gets product.
Embodiment 2
A fowl Chinese medicine oral liquid for control coccidiosis, the parts by weight of each raw material are as follows: Radix Puerariae 5 parts, the Radix Pulsatillae 10 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Osmundae 10 parts, Herba Agrimoniae 15 parts, Ramulus et Folium Dichroae febrifugae 15 parts, Rhizoma Coptidis 15 parts, Pericarpium Granati 15 parts, 200 parts, water.Its preparation method is: Chinese medicine powder is broken to 30-50 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, soak 5-20 hour; (3) hydrolyzed solution obtained after immersion is heated to 40 DEG C-100 DEG C, extracts 6-10 hour; (4) excessively filter medicinal residues, the direct fill of gained liquid (every bottle of 250ml) gets product.
Embodiment 3
A fowl Chinese medicine oral liquid for control coccidiosis, the parts by weight of each raw material are as follows: Radix Puerariae 9 parts, the Radix Pulsatillae 15 parts, Radix Sophorae Flavescentis 12 parts, Rhizoma Osmundae 12 parts, Herba Agrimoniae 12 parts, Ramulus et Folium Dichroae febrifugae 13 parts, Rhizoma Coptidis 13 parts, Pericarpium Granati 13 parts, 250 parts, water.Its preparation method is: Chinese medicine powder is broken to 30-50 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, soak 5-20 hour; (3) hydrolyzed solution obtained after immersion is heated to 40 DEG C-100 DEG C, extracts 6-10 hour; (4) excessively filter medicinal residues, the direct fill of gained liquid (every bottle of 250ml) gets product.
Clinical trial
Test 1:
White meat-type chickens field, Jiangsu, breeding stock 700,000, falls ill 60,000, is diagnosed as small intestinal coccidium infection through cuing open inspection.Wherein 20,000 use product obtained by embodiment 1.Drink water 300 jin, treat 3 days for every bottle.Medication second day symptom obviously alleviates, and within the 3rd day, except individually except serious symptom, jumpbogroup is cured.Cure rate reaches 95.8%.Another 20,000 use sulfa drugs sulfamonomethoxine sodium, and treat 5 days, the 3rd day starts to take effect, and within the 5th day, jumpbogroup is cured, cure rate 83.2%.Also have 20,000 to use triazine diclazuril, treat 5 days, the 3rd day starts to take effect, and the 5th day jumpbogroup is cured cure rate and reached 81.4%.The results are shown in Table 1.
Test proves that product curative effect obtained by embodiment 1 is obviously better than the chemicals of conventional treatment coccidiosis on market.
Test 2:
Sanhuang chicken plant of Hebei province, breeding stock 100,000, falls ill 10,000 5 thousand, is diagnosed as small intestinal coccidiosis holds concurrently coli-infection through cuing open inspection.Wherein 5,000 use product obtained by embodiment 1.Drink water 300 jin, treat 4 days for every bottle.Medication second day symptom obviously alleviates, and within the 4th day, except indivedual mixed sense serious symptom, jumpbogroup is cured.Cure rate reaches 96.8%.Another 5,000 use sulfa drugs sulfamonomethoxine sodium, and treat 4 days, second day starts to take effect, and within the 4th day, jumpbogroup is cured, cure rate 77.2%.Another 5,000 use triazine diclazuril.The results are shown in Table 1.
Test proves that product curative effect obtained by embodiment 1 is obviously better than the chemicals of conventional treatment coccidiosis on market.
Other result of the tests are in table 1.
Table 1
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (8)
1. a fowl Chinese medicine composition for control coccidiosis, is characterized in that: be prepared from by the raw material of following mass fraction: Radix Puerariae 5-10 part, Radix Pulsatillae 10-20 part, Radix Sophorae Flavescentis 10-15 part, Rhizoma Osmundae 10-15 part, Herba Agrimoniae 10-15 part, Ramulus et Folium Dichroae febrifugae 10-15 part, Rhizoma Coptidis 10-15 part, Pericarpium Granati 10-15 part; This Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
2. the fowl according to claim 1 Chinese medicine composition of control coccidiosis, is characterized in that: the mass fraction of optimum feed stock is as follows:
Radix Puerariae 10 parts, the Radix Pulsatillae 20 parts, Radix Sophorae Flavescentis 15 parts, Rhizoma Osmundae 15 parts, Herba Agrimoniae 10 parts, Ramulus et Folium Dichroae febrifugae 10 parts, Rhizoma Coptidis 10 parts, Pericarpium Granati 10 parts.
3. the fowl according to claim 2 Chinese medicine composition of control coccidiosis, it is characterized in that: described preparation can be oral liquid, now the input amount of water is 100-300 part.
4. prepare a method for the Chinese medicine composition of fowl as claimed in claim 1 control coccidiosis, it is characterized in that: preparation method is: Chinese medicine is pulverized by (1), and take by formula ratio, three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot and soaked; (3) the hydrolyzed solution heating will obtained after immersion, extracts; (4) excessively filter medicinal residues, the direct fill of gained liquid gets product.
5. the fowl according to claim 4 preparation method of the Chinese medicine composition of control coccidiosis, is characterized in that: described pulverizing order number is 30-50 order.
6. the fowl according to claim 4 preparation method of the Chinese medicine composition of control coccidiosis, is characterized in that: described soak time is 5-20 hour.
7. the fowl according to claim 4 preparation method of the Chinese medicine composition of control coccidiosis, is characterized in that: described heating temperature range is 40 DEG C-100 DEG C.
8. the fowl according to claim 4 preparation method of the Chinese medicine composition of control coccidiosis, is characterized in that: described extraction time is 6-10 hour.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104758390B (en) * | 2014-12-10 | 2018-04-24 | 北京康华远景科技股份有限公司 | Prevent plant drug compound preparation of diarrhea of pigs and preparation method thereof |
| CN105797048A (en) * | 2016-04-21 | 2016-07-27 | 颍上县中军农业科技开发有限公司 | Drug for controlling coccidiosis in pigeons |
| CN107582659A (en) * | 2016-07-08 | 2018-01-16 | 施瑞客（天津）生物技术有限公司 | A kind of Chinese medicine composition for treating el pato's parasitosis and preparation method thereof |
| CN107898841B (en) * | 2016-08-31 | 2020-10-13 | 旌德县德源农业开发有限公司 | Medicine for preventing and treating chicken coccidiosis and preparation method and application thereof |
| CN106389741A (en) * | 2016-09-30 | 2017-02-15 | 安徽华澳生物技术有限公司 | Medicament for preventing and treating chicken coccidiosis |
| CN113813373B (en) * | 2021-11-15 | 2024-07-16 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for repairing intestinal mucosa and improving mucosal immune function and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927281A (en) * | 2006-09-01 | 2007-03-14 | 浙江省农业科学院 | Chinese herbal medicine slow release agent for preventing and treating rabbit and chicken coccidiosis and preparing method thereof |
| CN102319318A (en) * | 2011-09-30 | 2012-01-18 | 山东省健牧生物药业有限公司 | Chinese medicinal superfine powder preparation for preventing and treating heat toxin and blood dysentery of chicken and preparation method thereof |
| CN102670936A (en) * | 2012-06-03 | 2012-09-19 | 遂宁市珠珠农牧发展有限公司 | Traditional Chinese medicine preparation for treating viral enteritis and diarrhea |
| CN102813726A (en) * | 2012-09-08 | 2012-12-12 | 林初文 | Compound traditional Chinese medicine submicron powder preparation for preventing and treating humid-heat diarrhea of poultry and preparation method thereof |
| CN103202974A (en) * | 2013-04-25 | 2013-07-17 | 青岛农业大学 | Traditional Chinese medicine composition for treating coccidiosis in chicken |
| CN103565987A (en) * | 2012-07-26 | 2014-02-12 | 吴昊 | Traditional Chinese medicine powder for treating silky coccidiosis |
-
2014
- 2014-07-01 CN CN201410312481.XA patent/CN104027420B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927281A (en) * | 2006-09-01 | 2007-03-14 | 浙江省农业科学院 | Chinese herbal medicine slow release agent for preventing and treating rabbit and chicken coccidiosis and preparing method thereof |
| CN102319318A (en) * | 2011-09-30 | 2012-01-18 | 山东省健牧生物药业有限公司 | Chinese medicinal superfine powder preparation for preventing and treating heat toxin and blood dysentery of chicken and preparation method thereof |
| CN102670936A (en) * | 2012-06-03 | 2012-09-19 | 遂宁市珠珠农牧发展有限公司 | Traditional Chinese medicine preparation for treating viral enteritis and diarrhea |
| CN103565987A (en) * | 2012-07-26 | 2014-02-12 | 吴昊 | Traditional Chinese medicine powder for treating silky coccidiosis |
| CN102813726A (en) * | 2012-09-08 | 2012-12-12 | 林初文 | Compound traditional Chinese medicine submicron powder preparation for preventing and treating humid-heat diarrhea of poultry and preparation method thereof |
| CN103202974A (en) * | 2013-04-25 | 2013-07-17 | 青岛农业大学 | Traditional Chinese medicine composition for treating coccidiosis in chicken |
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