CN107898841B - Medicine for preventing and treating chicken coccidiosis and preparation method and application thereof - Google Patents
Medicine for preventing and treating chicken coccidiosis and preparation method and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a medicine for preventing and treating chicken coccidiosis and a preparation method and application thereof, wherein the medicine is prepared from the following raw materials in parts by weight: 15-23 parts of hairyvein agrimony, 3-8 parts of medical stone, 1-5 parts of radix sophorae flavescentis, 20-30 parts of cardamine hirsute and 8-16 parts of radix angelicae pubescentis. Pulverizing radix Sophorae Flavescentis to obtain radix Sophorae Flavescentis powder; pulverizing Maifanitum, adding edible vinegar, and heat treating to obtain Maifanitum powder; mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, decocting with deionized water with slow fire, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, ultrasonic processing, and oven drying to obtain the medicine. The Chinese medicinal composition has the effects of killing insects, clearing heat, promoting blood circulation to stop bleeding, eliminating dampness and converging, has a remarkable curative effect on chicken coccidiosis, is high in cure rate, free of relapse after cure, quick in effect, small in dosage, capable of improving the immune function and enhancing the disease resistance of chicken, remarkably reduces pathological changes such as intestinal pathological changes and bleeding after administration, remarkably increases weight, does not have any toxic or side effect, improves meat quality, and is suitable for large-scale production.
Description
Technical Field
The invention relates to the technical field of veterinary drugs, in particular to a drug for preventing and treating chicken coccidiosis and a preparation method and application thereof.
Background
Coccidiosis is a parasitic disease that damages the gut of poultry. Coccidiosis is a disease that many commercial poultry growers in the united states are afraid of. Death losses above 20% are a common phenomenon. Coccidiosis is not a problem since "backyard" poultry is generally kept in small quantities, but as the number of free-ranging birds increases, coccidiosis has become a great threat. Among them, Chicken Coccidiosis (Coccidiosis in Chicken) is a common and serious parasitic disease of Chicken, and is an acute epidemic parasitic disease caused by one or more coccidia. The economic losses caused by it are surprising. The morbidity and mortality of chicks of 10-30 days old or young chickens of 35-60 days old can reach 80%. The growth of the healed chicks is hindered, and the weight gain is slow; adult chickens generally do not develop disease, but are carriers of the disease, and have reduced weight gain and egg laying capacity, and are important sources of disease for spreading coccidiosis. The western medicine treatment uses antibiotics, antiviral drugs and the like, the drug residue is large, drug resistance is easy to generate, the illness state is easy to repeat, and people eat the chicken has certain adverse effects on the health of the organism. The cured chicken has poor meat quality.
Disclosure of Invention
The invention aims to provide a medicine for preventing and treating chicken coccidiosis, which has the advantages of good curative effect, no public nuisance, no residue, improvement of immunity, meat quality and weight and convenient use, and a preparation method and application thereof, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 15-23 parts of hairyvein agrimony, 3-8 parts of medical stone, 1-5 parts of radix sophorae flavescentis, 20-30 parts of cardamine hirsute and 8-16 parts of radix angelicae pubescentis.
As a further scheme of the invention: the medicine for preventing and treating chicken coccidiosis is composed of the following raw materials in parts by weight: 17-21 parts of hairyvein agrimony, 4-7 parts of medical stone, 2-4 parts of radix sophorae flavescentis, 23-27 parts of cardamine hirsute and 10-14 parts of radix angelicae pubescentis.
As a further scheme of the invention: the medicine for preventing and treating chicken coccidiosis is composed of the following raw materials in parts by weight: 19 parts of hairyvein agrimony, 5 parts of medical stone, 3 parts of radix sophorae flavescentis, 25 parts of cardamine hirsuta and 12 parts of radix angelicae pubescentis.
The invention also aims to provide a preparation method of the medicine for preventing and treating chicken coccidiosis, which comprises the following steps:
1) pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder;
2) pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3-4 times the mass of Maifanitum, stirring at 68 deg.C for 30-35min, and stirring at 85 deg.C to dry to obtain Maifanitum powder;
3) mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 60-80 mesh sieve, adding deionized water 15 times of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
The invention also aims to provide application of the medicine in preparing a medicine for preventing and treating chicken coccidiosis.
Herba et Gemma Agrimoniae has effects of astringing to stop bleeding, preventing malaria, stopping dysentery, removing toxic substance, and tonifying deficiency. It can be used for treating hemoptysis, hematemesis, metrorrhagia, malaria, dysentery with bloody stool, carbuncle, suppurative sore, pudendal pruritus, leukorrhagia, and asthenia.
The effect of medical stone on poultry: the method has the advantages of reducing death rate, preventing diarrhea, ensuring normal intestine function, preventing intestinal flatulence, improving meat quality, reducing fat content, improving the quality of required feed, preventing poultry from being tensed and pecking each other, and eliminating excrement peculiar smell.
Kuh-seng has the functions of clearing heat and drying dampness, killing parasites and promoting urination. Can be used for treating dysentery with heat, hematochezia, jaundice, anuria, leucorrhea with red and white discharge, pudendal swelling, pudendal pruritus, eczema, skin pruritus, scabies, tinea, leprosy, and trichomonas vaginitis.
The cardamine bursa-pastoris has the effects of promoting blood circulation to regulate menstruation, clearing away heat and toxic materials, and inducing diuresis for treating stranguria. It is commonly indicated for irregular menstruation, swollen abscess and stranguria.
Radix Angelicae Pubescentis has effects of dispelling pathogenic wind, removing dampness, relieving pain and arthralgia. It can be used for treating arthralgia due to wind-cold-dampness, pain due to washing, headache due to wind-cold-dampness, and shaoyin headache.
Compared with the prior art, the invention has the beneficial effects that:
under the synergistic action of the raw materials, the Chinese medicinal composition has the effects of killing insects, clearing heat, promoting blood circulation to stop bleeding, eliminating dampness and converging, has a remarkable curative effect on chicken coccidiosis, is high in cure rate, free of relapse after cure, quick in effect taking, small in dosage, capable of improving the immunity and enhancing the disease resistance of chicken, remarkably reduces intestinal lesions, bleeding and other lesions after administration, remarkably increases the weight, does not have any toxic or side effect, improves the meat quality, and is a medicament which is good in curative effect, free of public hazard, free of residue and convenient to use. The invention has the advantages of simple and wide material sources, simple and easily controlled preparation process and suitability for large-scale production.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
In the embodiment of the invention, the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 15 parts of hairyvein agrimony, 3 parts of medical stone, 1 part of radix sophorae flavescentis, 20 parts of cardamine hirsuta and 8 parts of radix angelicae pubescentis.
Pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder. Pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3 times the mass of Maifanitum, stirring at 68 deg.C for 30min, and stirring at 85 deg.C to dry to obtain Maifanitum powder. Mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 60 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
Example 2
In the embodiment of the invention, the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 23 parts of hairyvein agrimony, 8 parts of medical stone, 5 parts of radix sophorae flavescentis, 30 parts of cardamine hirsuta and 16 parts of radix angelicae pubescentis.
Pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder. Pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 4 times the mass of Maifanitum, stirring at 68 deg.C for 35min, and stirring at 85 deg.C to dry to obtain Maifanitum powder. Mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 80 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
Example 3
In the embodiment of the invention, the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 17 parts of hairyvein agrimony, 4 parts of medical stone, 2 parts of radix sophorae flavescentis, 23 parts of cardamine hirsuta and 10 parts of radix angelicae pubescentis.
Pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder. Pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3.5 times the mass of Maifanitum, stirring at 68 deg.C for 32min, and stirring at 85 deg.C to dry to obtain Maifanitum powder. Mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 70 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
Example 4
In the embodiment of the invention, the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 21 parts of hairyvein agrimony, 7 parts of medical stone, 4 parts of radix sophorae flavescentis, 27 parts of cardamine hirsuta and 14 parts of radix angelicae pubescentis.
Pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder. Pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3.5 times the mass of Maifanitum, stirring at 68 deg.C for 32min, and stirring at 85 deg.C to dry to obtain Maifanitum powder. Mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 70 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
Example 5
In the embodiment of the invention, the medicine for preventing and treating chicken coccidiosis is prepared from the following raw materials in parts by weight: 19 parts of hairyvein agrimony, 5 parts of medical stone, 3 parts of radix sophorae flavescentis, 25 parts of cardamine hirsuta and 12 parts of radix angelicae pubescentis.
Pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder. Pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3.5 times the mass of Maifanitum, stirring at 68 deg.C for 32min, and stirring at 85 deg.C to dry to obtain Maifanitum powder. Mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 70 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
Comparative example 1
The formulation and preparation were the same as in example 5 except that cardamine elasticum was not included.
Comparative example 2
Only cardamine bombycis was included and the preparation was the same as in example 5.
EXAMPLE 6 clinical trial
(1) Material preparation
500 chicks in a chicken farm just out of the housing are raised under the strict isolation condition without coccidia, and 200 chicks with uniform weight are randomly picked as a preventive contrast test object at the age of 15 days; 200 uniform body weights were randomly picked as treatment control subjects.
(2) Preventive contrast test
Randomly picked 15-day-old local chickens as preventive comparative test subjects were randomly divided into 5 groups (control 1 group, control 2 group, control 3 group, blank group and example group), wherein the example group was fed with the feed to which the drug of example 5 was added, the drug addition amount was 0.5% of the feed treatment, the control 1 group was fed with the feed to which the drug of comparative example 1 was added, the control 2 group was fed with the feed to which the drug of comparative example 2 was added, the control 3 group and blank group were fed with the conventional local chicken feed, and after 7 days of feeding, 202 × 10 was artificially infected to each of the control 1-3 groups and the example group4Observing and recording the morbidity and mortality of each group of local chickens by the coccidian oocysts of the mixed local chickens, and weighing all the local chickens one by one after the test (when the local chickens are 25 days old); the results are shown in Table 1.
Weight gain (%) = (average weight of test chicken at end of test and average weight of test chicken at start of test) × 100/average weight gain of non-infected non-dosed test chicken
TABLE 1 preventive effect comparison table
| Group of | Total number of | Number of artificial infections | Incidence of disease | Mortality rate | Rate of protection | Rate of weight gain |
| Group of embodiments | 40 | 40 | 0% | 0% | 100% | 88.5% |
| Control 1 group | 40 | 40 | 60% | 35% | 65% | 53.7% |
| Control 2 group | 40 | 40 | 90% | 85% | 15% | 10.3% |
| Control 3 group | 40 | 40 | 100% | 100% | 0% | 19.8% |
| Blank group | 40 | 0 | 0 | 0 | 100% | 100% |
From the data in table 1, it can be seen that: the feed containing the medicine has obvious effect of preventing the coccidiosis of the local chicken.
(3) Treatment comparative experiment:
randomly dividing 200 randomly-grabbed 15-day-old local chickens serving as treatment contrast test objects into 5 groups (a medicine group, a control 1 group, a control 2 group, a western medicine treatment group and a blank control group), wherein each artificial infection is 202 x 104Mixing the native chicken coccidian oocysts, and treating with different medicines after clinical symptoms appear, wherein the medicine group adopts the medicine of example 5, the dosage is 30mg/kg, and the treatment lasts for 10 days; the control group 1 adopts the medicine of the comparative example 1, the dosage is 30mg/kg, and the treatment lasts for 10 days; the control group 2 adopts the medicine of the comparative example 2, the dosage is 30mg/kg, and the treatment lasts for 10 days; the western medicine treatment group is natamycin, the dosage is 70mg/kg, and the treatment lasts for 10 days; the blank control group was not fed any drug. The incidence, cure and mortality of the local chickens in each group were observed and recorded, and the results are shown in table 2.
TABLE 2 comparison of therapeutic effects
| Group of | Number of onset of disease | Incidence of disease | Number of deaths | Mortality rate | Number of cure | Cure rate |
| Drug group | 40 | 100% | 0 | 0 | 40 | 100% |
| Control 1 group | 40 | 100% | 20 | 50% | 20 | 50% |
| Control 2 group | 40 | 100% | 37 | 92.5% | 3 | 7.5% |
| Western medicine treatment group | 40 | 100% | 18 | 45% | 22 | 55% |
| Blank control group | 40 | 100% | 40 | 100% | 0 | 0 |
The data in the table 2 show that the treatment effect of the medicine on the coccidiosis in the local chicken is obviously superior to that of a western medicine treatment group, the mortality rate of the medicine is reduced, and the cure rate is improved; compared with the control group 1-2, the invention has the advantages of playing the role under the synergistic action of all the raw materials, having no toxic or side effect in the treatment process and improving the meat quality. The invention has significant progress.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (9)
1. The medicine for preventing and treating chicken coccidiosis is characterized by comprising the following raw materials in parts by weight: 15 parts of hairyvein agrimony, 3 parts of medical stone, 1 part of radix sophorae flavescentis, 20 parts of cardamine hirsuta and 8 parts of radix angelicae pubescentis.
2. The preparation method of the medicine for preventing and treating chicken coccidiosis according to claim 1, which is characterized by comprising the following steps: pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder; pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3 times the mass of Maifanitum, stirring at 68 deg.C for 30min, and stirring at 85 deg.C to dry to obtain Maifanitum powder; mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 60 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
3. The medicine for preventing and treating chicken coccidiosis is characterized by comprising the following raw materials in parts by weight: 23 parts of hairyvein agrimony, 8 parts of medical stone, 5 parts of radix sophorae flavescentis, 30 parts of cardamine hirsuta and 16 parts of radix angelicae pubescentis.
4. The preparation method of the medicine for preventing and treating chicken coccidiosis as claimed in claim 3, which comprises the following steps: pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder; pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 4 times the mass of Maifanitum, stirring at 68 deg.C for 35min, and stirring at 85 deg.C to dry to obtain Maifanitum powder; mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 80 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
5. The medicine for preventing and treating chicken coccidiosis is characterized by comprising the following raw materials in parts by weight: 17 parts of hairyvein agrimony, 4 parts of medical stone, 2 parts of radix sophorae flavescentis, 23 parts of cardamine hirsuta and 10 parts of radix angelicae pubescentis.
6. The preparation method of the medicine for preventing and treating chicken coccidiosis as claimed in claim 5, which comprises the following steps: pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder; pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3.5 times the mass of Maifanitum, stirring at 68 deg.C for 32min, and stirring at 85 deg.C to dry to obtain Maifanitum powder; mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 70 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
7. The medicine for preventing and treating chicken coccidiosis is characterized by comprising the following raw materials in parts by weight: 21 parts of hairyvein agrimony, 7 parts of medical stone, 4 parts of radix sophorae flavescentis, 27 parts of cardamine hirsuta and 14 parts of radix angelicae pubescentis.
8. The preparation method of the medicine for preventing and treating chicken coccidiosis as claimed in claim 7, which comprises the following steps: pulverizing radix Sophorae Flavescentis, and sieving with 200 mesh sieve to obtain radix Sophorae Flavescentis powder; pulverizing Maifanitum, sieving with 150 mesh sieve, adding edible vinegar 3.5 times the mass of Maifanitum, stirring at 68 deg.C for 32min, and stirring at 85 deg.C to dry to obtain Maifanitum powder; mixing herba et Gemma Agrimoniae, herba Capsellae and radix Angelicae Pubescentis, pulverizing, sieving with 70 mesh sieve, adding deionized water 15 times the mass of the three materials, decocting with slow fire for 2.5h, filtering to obtain filtrate, mixing with radix Sophorae Flavescentis powder and Maifanitum powder, performing ultrasonic treatment with ultrasonic power of 500W and ultrasonic time of 30min, and oven drying to obtain the medicine.
9. Use of the medicament according to any one of claims 1, 3, 5 or 7 for the preparation of a medicament for the prevention and treatment of coccidiosis in chicken.
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| CN201610779909.0A CN106214778B (en) | 2016-08-31 | 2016-08-31 | A kind of medicine for preventing and treating chicken coccidiasis and its preparation method and application |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217880B1 (en) * | 1998-07-24 | 2001-04-17 | Jinchu Lan | Medicament for treating recurrent ulcer of mouth and behcet's syndrome |
| CN103860715A (en) * | 2013-05-16 | 2014-06-18 | 武汉市畜牧兽医科学研究所 | Compound traditional Chinese medicine extract for preventing poultry coccidiosis and application of extract |
| CN104027420A (en) * | 2014-07-01 | 2014-09-10 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine composition for prevention and treatment of coccidiosis of poultry and preparation method thereof |
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| CN104758417A (en) * | 2015-03-06 | 2015-07-08 | 钟云仙 | Chinese medicinal composition for treatment of chicken coccidiosis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217880B1 (en) * | 1998-07-24 | 2001-04-17 | Jinchu Lan | Medicament for treating recurrent ulcer of mouth and behcet's syndrome |
| CN103860715A (en) * | 2013-05-16 | 2014-06-18 | 武汉市畜牧兽医科学研究所 | Compound traditional Chinese medicine extract for preventing poultry coccidiosis and application of extract |
| CN104027420A (en) * | 2014-07-01 | 2014-09-10 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine composition for prevention and treatment of coccidiosis of poultry and preparation method thereof |
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| CN107898841A (en) | 2018-04-13 |
| CN106214778B (en) | 2017-12-01 |
| CN106214778A (en) | 2016-12-14 |
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