CN104010635A - 包含trpv1选择性激动剂的止痛组合物及其制备和应用 - Google Patents

包含trpv1选择性激动剂的止痛组合物及其制备和应用 Download PDF

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Publication number
CN104010635A
CN104010635A CN201280055002.XA CN201280055002A CN104010635A CN 104010635 A CN104010635 A CN 104010635A CN 201280055002 A CN201280055002 A CN 201280055002A CN 104010635 A CN104010635 A CN 104010635A
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China
Prior art keywords
composition
capsaicin
pain
weight
methyl salicylate
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Pending
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CN201280055002.XA
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Chinese (zh)
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丹尼尔·巴克斯
菲利普·J·比尔巴拉
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API Genesis LLC
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API Genesis LLC
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
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    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
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    • A61K31/12—Ketones
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    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN201280055002.XA 2011-09-09 2012-09-10 包含trpv1选择性激动剂的止痛组合物及其制备和应用 Pending CN104010635A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161533120P 2011-09-09 2011-09-09
US61/533,120 2011-09-09
US201261642942P 2012-05-04 2012-05-04
US61/642,942 2012-05-04
PCT/US2012/054511 WO2013036961A1 (en) 2011-09-09 2012-09-10 A pain relief composition, comprising a trpv1 selective agonist, and manufacture and uses thereof

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CN104010635A true CN104010635A (zh) 2014-08-27

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US (5) US8889659B2 (cg-RX-API-DMAC7.html)
EP (2) EP3388057B1 (cg-RX-API-DMAC7.html)
JP (1) JP6228540B2 (cg-RX-API-DMAC7.html)
KR (1) KR101769010B1 (cg-RX-API-DMAC7.html)
CN (1) CN104010635A (cg-RX-API-DMAC7.html)
BR (1) BR112014005358A8 (cg-RX-API-DMAC7.html)
CA (1) CA2854206C (cg-RX-API-DMAC7.html)
MX (1) MX347902B (cg-RX-API-DMAC7.html)
WO (1) WO2013036961A1 (cg-RX-API-DMAC7.html)

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CN113662739A (zh) * 2021-08-20 2021-11-19 刘浩泉 一种冰敷贴及其制作方法
CN114652708A (zh) * 2022-03-07 2022-06-24 宁波奇致年华医疗科技有限公司 一种治疗深部组织疼痛的组合物
CN114917190A (zh) * 2022-06-13 2022-08-19 郑州味千生物技术有限公司 用于掩盖苦味的产品

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KR20200119351A (ko) 2012-11-12 2020-10-19 비쭈리 헬스 사이언스 엘엘씨 수계 캡사이시노이드 제형 및 제조 방법 및 용도
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JP6508671B2 (ja) * 2015-01-30 2019-05-08 ハウスウェルネスフーズ株式会社 トウガラシ抽出物及び／又はショウガ抽出物を含む組成物、ならびにその製造方法
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US20200375915A1 (en) * 2017-04-25 2020-12-03 Srinivas Reddy Male Matrix adhesive patch and process for the preparation thereof
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WO2020223092A1 (en) * 2019-04-30 2020-11-05 Bayer Healthcare Llc Topical analgesic spray compositions
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EP4009944B1 (en) * 2019-08-05 2024-12-25 CS Medica A/S Topical formulations comprising cannabidiol, method of preparing the composition and use thereof
AU2021238637B2 (en) 2020-03-17 2025-12-18 Grünenthal GmbH Repeated topical application of capsaicin patch for treating initial non-responders
WO2021198524A1 (en) 2020-04-03 2021-10-07 Grünenthal GmbH Regimen for repeated topical application of capsaicin patch
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