CN103946241A - 赖氨酰氧化酶样2分析法及其使用方法 - Google Patents

赖氨酰氧化酶样2分析法及其使用方法 Download PDF

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Publication number
CN103946241A
CN103946241A CN201280037235.7A CN201280037235A CN103946241A CN 103946241 A CN103946241 A CN 103946241A CN 201280037235 A CN201280037235 A CN 201280037235A CN 103946241 A CN103946241 A CN 103946241A
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CN
China
Prior art keywords
loxl2
antibody
disease
individual
fibrosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280037235.7A
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English (en)
Chinese (zh)
Inventor
维多利亚·史密斯
乔安妮·I.·阿达姆科维兹
苏珊·K.·莱曼
詹森·钱
李晓明
邵立新
杰弗瑞·D.·伯恩斯坦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Biologics Inc
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Gilead Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46208194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN103946241(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Biologics Inc filed Critical Gilead Biologics Inc
Publication of CN103946241A publication Critical patent/CN103946241A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silicon Polymers (AREA)
CN201280037235.7A 2011-06-01 2012-06-01 赖氨酰氧化酶样2分析法及其使用方法 Pending CN103946241A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161492210P 2011-06-01 2011-06-01
US61/492,210 2011-06-01
US201161550895P 2011-10-24 2011-10-24
US61/550,895 2011-10-24
US201161578813P 2011-12-21 2011-12-21
US61/578,813 2011-12-21
PCT/US2012/040585 WO2012167181A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Publications (1)

Publication Number Publication Date
CN103946241A true CN103946241A (zh) 2014-07-23

Family

ID=46208194

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280037235.7A Pending CN103946241A (zh) 2011-06-01 2012-06-01 赖氨酰氧化酶样2分析法及其使用方法

Country Status (25)

Country Link
US (3) US20140206017A1 (https=)
EP (1) EP2714744A1 (https=)
JP (3) JP2014523521A (https=)
KR (1) KR20140048156A (https=)
CN (1) CN103946241A (https=)
AP (1) AP2013007285A0 (https=)
AR (1) AR086657A1 (https=)
AU (2) AU2012261883A1 (https=)
BR (1) BR112013030682A2 (https=)
CA (1) CA2837534A1 (https=)
CL (1) CL2013003445A1 (https=)
CO (1) CO6940375A2 (https=)
CR (1) CR20130657A (https=)
EA (1) EA201391627A1 (https=)
EC (1) ECSP13013092A (https=)
IL (1) IL229631A0 (https=)
MA (1) MA35212B1 (https=)
MD (1) MD20130098A2 (https=)
MX (1) MX2013013905A (https=)
PE (1) PE20141450A1 (https=)
PH (1) PH12013502490A1 (https=)
TW (1) TW201319572A (https=)
UY (1) UY34115A (https=)
WO (1) WO2012167181A1 (https=)
ZA (1) ZA201308812B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
CA2693310C (en) * 2007-08-02 2018-11-27 Arresto Biosciences, Inc. Lox and loxl2 inhibitors, antibodies and uses thereof
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
EP2467396A4 (en) 2009-08-21 2012-12-26 Gilead Biologics Inc CATALYTIC DOMAINS FROM LYSYL OXIDASE AND LOXL2
US8680246B2 (en) * 2010-02-04 2014-03-25 Gilead Biologics, Inc. Antibodies that bind to lysyl oxidase-like 2 (LOXL2)
EP3348576A1 (en) * 2012-10-30 2018-07-18 Gilead Sciences, Inc. Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2)
US20150342943A1 (en) 2014-06-03 2015-12-03 Gilead Sciences, Inc. Methods of treating liver disease
EA201692202A1 (ru) * 2014-06-11 2017-06-30 Джилид Сайэнс, Инк. Способы лечения сердечно-сосудистых заболеваний
MA41252A (fr) 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
AU2017228371A1 (en) 2016-03-04 2018-09-13 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
AU2017248354A1 (en) 2016-04-08 2018-10-04 Gilead Sciences, Inc. Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
GB201704206D0 (en) 2017-03-16 2017-05-03 Nordic Bioscience As Lysyl oxidase like-2 assay
US20230152330A1 (en) * 2021-11-17 2023-05-18 AmMax Bio, Inc. Detection and treatment of idiopathic pulmonary fibrosis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US20090053224A1 (en) * 2007-08-02 2009-02-26 Arresto Biosciences Lox and loxl2 inhibitors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
AU2010283997B2 (en) * 2009-08-21 2015-04-09 Gilead Biologics, Inc. Methods and compositions for treatment of pulmonary fibrotic disorders
US8680246B2 (en) * 2010-02-04 2014-03-25 Gilead Biologics, Inc. Antibodies that bind to lysyl oxidase-like 2 (LOXL2)
US9556882B2 (en) * 2011-05-10 2017-01-31 Borgwarner Inc. Turbocharger with variable turbine geometry

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US20090053224A1 (en) * 2007-08-02 2009-02-26 Arresto Biosciences Lox and loxl2 inhibitors and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PEINADO H ET AL: "A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression", 《EMBO JOURNAL》, vol. 24, no. 19, 5 October 2005 (2005-10-05), pages 3446 - 3458 *

Also Published As

Publication number Publication date
EA201391627A1 (ru) 2014-08-29
CR20130657A (es) 2014-05-16
JP2018049033A (ja) 2018-03-29
WO2012167181A1 (en) 2012-12-06
CA2837534A1 (en) 2012-12-06
AU2016244254B2 (en) 2018-10-18
AR086657A1 (es) 2014-01-15
ECSP13013092A (es) 2014-08-29
JP2016164578A (ja) 2016-09-08
US20140206017A1 (en) 2014-07-24
CO6940375A2 (es) 2014-05-09
BR112013030682A2 (pt) 2016-12-06
JP2014523521A (ja) 2014-09-11
IL229631A0 (en) 2014-01-30
ZA201308812B (en) 2014-08-27
TW201319572A (zh) 2013-05-16
NZ618682A (en) 2016-04-29
KR20140048156A (ko) 2014-04-23
MX2013013905A (es) 2014-05-14
UY34115A (es) 2013-01-03
US20120309020A1 (en) 2012-12-06
AU2012261883A1 (en) 2013-05-02
AP2013007285A0 (en) 2013-11-30
AU2016244254A1 (en) 2016-11-03
PE20141450A1 (es) 2014-11-06
EP2714744A1 (en) 2014-04-09
US20170269085A1 (en) 2017-09-21
CL2013003445A1 (es) 2014-07-25
MD20130098A2 (ro) 2014-06-30
MA35212B1 (fr) 2014-06-02
PH12013502490A1 (en) 2014-01-20

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Application publication date: 20140723