CA2837534A1 - Lysyl oxidase-like 2 assay and methods of use thereof - Google Patents
Lysyl oxidase-like 2 assay and methods of use thereof Download PDFInfo
- Publication number
- CA2837534A1 CA2837534A1 CA2837534A CA2837534A CA2837534A1 CA 2837534 A1 CA2837534 A1 CA 2837534A1 CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A1 CA2837534 A1 CA 2837534A1
- Authority
- CA
- Canada
- Prior art keywords
- loxl2
- antibody
- disease
- individual
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492210P | 2011-06-01 | 2011-06-01 | |
| US61/492,210 | 2011-06-01 | ||
| US201161550895P | 2011-10-24 | 2011-10-24 | |
| US61/550,895 | 2011-10-24 | ||
| US201161578813P | 2011-12-21 | 2011-12-21 | |
| US61/578,813 | 2011-12-21 | ||
| PCT/US2012/040585 WO2012167181A1 (en) | 2011-06-01 | 2012-06-01 | Lysyl oxidase-like 2 assay and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2837534A1 true CA2837534A1 (en) | 2012-12-06 |
Family
ID=46208194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2837534A Abandoned CA2837534A1 (en) | 2011-06-01 | 2012-06-01 | Lysyl oxidase-like 2 assay and methods of use thereof |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US20140206017A1 (https=) |
| EP (1) | EP2714744A1 (https=) |
| JP (3) | JP2014523521A (https=) |
| KR (1) | KR20140048156A (https=) |
| CN (1) | CN103946241A (https=) |
| AP (1) | AP2013007285A0 (https=) |
| AR (1) | AR086657A1 (https=) |
| AU (2) | AU2012261883A1 (https=) |
| BR (1) | BR112013030682A2 (https=) |
| CA (1) | CA2837534A1 (https=) |
| CL (1) | CL2013003445A1 (https=) |
| CO (1) | CO6940375A2 (https=) |
| CR (1) | CR20130657A (https=) |
| EA (1) | EA201391627A1 (https=) |
| EC (1) | ECSP13013092A (https=) |
| IL (1) | IL229631A0 (https=) |
| MA (1) | MA35212B1 (https=) |
| MD (1) | MD20130098A2 (https=) |
| MX (1) | MX2013013905A (https=) |
| PE (1) | PE20141450A1 (https=) |
| PH (1) | PH12013502490A1 (https=) |
| TW (1) | TW201319572A (https=) |
| UY (1) | UY34115A (https=) |
| WO (1) | WO2012167181A1 (https=) |
| ZA (1) | ZA201308812B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030114410A1 (en) | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CA2693310C (en) * | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| WO2010080769A2 (en) | 2009-01-06 | 2010-07-15 | Arresto Biosciences, Inc. | Chemotherapeutic methods and compositions |
| EP2467396A4 (en) | 2009-08-21 | 2012-12-26 | Gilead Biologics Inc | CATALYTIC DOMAINS FROM LYSYL OXIDASE AND LOXL2 |
| US8680246B2 (en) * | 2010-02-04 | 2014-03-25 | Gilead Biologics, Inc. | Antibodies that bind to lysyl oxidase-like 2 (LOXL2) |
| EP3348576A1 (en) * | 2012-10-30 | 2018-07-18 | Gilead Sciences, Inc. | Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2) |
| US20150342943A1 (en) | 2014-06-03 | 2015-12-03 | Gilead Sciences, Inc. | Methods of treating liver disease |
| EA201692202A1 (ru) * | 2014-06-11 | 2017-06-30 | Джилид Сайэнс, Инк. | Способы лечения сердечно-сосудистых заболеваний |
| MA41252A (fr) | 2014-12-23 | 2017-10-31 | Gilead Sciences Inc | Formes solides d'un inhibiteur d'ask 1 |
| AU2017228371A1 (en) | 2016-03-04 | 2018-09-13 | Gilead Sciences, Inc. | Compositions and combinations of autotaxin inhibitors |
| AU2017248354A1 (en) | 2016-04-08 | 2018-10-04 | Gilead Sciences, Inc. | Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases |
| GB201704206D0 (en) | 2017-03-16 | 2017-05-03 | Nordic Bioscience As | Lysyl oxidase like-2 assay |
| US20230152330A1 (en) * | 2021-11-17 | 2023-05-18 | AmMax Bio, Inc. | Detection and treatment of idiopathic pulmonary fibrosis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
| FI92882C (fi) * | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
| US20030114410A1 (en) * | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CA2693310C (en) * | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| JP2010038735A (ja) * | 2008-08-05 | 2010-02-18 | Terumo Corp | 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙 |
| AU2010283997B2 (en) * | 2009-08-21 | 2015-04-09 | Gilead Biologics, Inc. | Methods and compositions for treatment of pulmonary fibrotic disorders |
| US8680246B2 (en) * | 2010-02-04 | 2014-03-25 | Gilead Biologics, Inc. | Antibodies that bind to lysyl oxidase-like 2 (LOXL2) |
| US9556882B2 (en) * | 2011-05-10 | 2017-01-31 | Borgwarner Inc. | Turbocharger with variable turbine geometry |
-
2012
- 2012-06-01 EP EP12725601.4A patent/EP2714744A1/en not_active Withdrawn
- 2012-06-01 UY UY0001034115A patent/UY34115A/es not_active Application Discontinuation
- 2012-06-01 MD MDA20130098A patent/MD20130098A2/ro not_active Application Discontinuation
- 2012-06-01 US US14/122,984 patent/US20140206017A1/en not_active Abandoned
- 2012-06-01 JP JP2014513770A patent/JP2014523521A/ja not_active Withdrawn
- 2012-06-01 BR BR112013030682A patent/BR112013030682A2/pt not_active IP Right Cessation
- 2012-06-01 PH PH1/2013/502490A patent/PH12013502490A1/en unknown
- 2012-06-01 KR KR1020137034711A patent/KR20140048156A/ko not_active Withdrawn
- 2012-06-01 WO PCT/US2012/040585 patent/WO2012167181A1/en not_active Ceased
- 2012-06-01 AP AP2013007285A patent/AP2013007285A0/xx unknown
- 2012-06-01 MX MX2013013905A patent/MX2013013905A/es not_active Application Discontinuation
- 2012-06-01 AR ARP120101959A patent/AR086657A1/es unknown
- 2012-06-01 EA EA201391627A patent/EA201391627A1/ru unknown
- 2012-06-01 CN CN201280037235.7A patent/CN103946241A/zh active Pending
- 2012-06-01 CA CA2837534A patent/CA2837534A1/en not_active Abandoned
- 2012-06-01 TW TW101119847A patent/TW201319572A/zh unknown
- 2012-06-01 US US13/487,109 patent/US20120309020A1/en not_active Abandoned
- 2012-06-01 AU AU2012261883A patent/AU2012261883A1/en not_active Abandoned
- 2012-06-01 PE PE2013002739A patent/PE20141450A1/es not_active Application Discontinuation
-
2013
- 2013-11-25 ZA ZA2013/08812A patent/ZA201308812B/en unknown
- 2013-11-26 IL IL229631A patent/IL229631A0/en unknown
- 2013-11-29 CL CL2013003445A patent/CL2013003445A1/es unknown
- 2013-12-13 CR CR20130657A patent/CR20130657A/es unknown
- 2013-12-19 EC ECSP13013092 patent/ECSP13013092A/es unknown
- 2013-12-27 CO CO13301122A patent/CO6940375A2/es unknown
- 2013-12-30 MA MA36627A patent/MA35212B1/fr unknown
-
2016
- 2016-06-09 JP JP2016115175A patent/JP2016164578A/ja active Pending
- 2016-10-12 AU AU2016244254A patent/AU2016244254B2/en not_active Ceased
- 2016-12-01 US US15/366,986 patent/US20170269085A1/en not_active Abandoned
-
2017
- 2017-11-16 JP JP2017221000A patent/JP2018049033A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EA201391627A1 (ru) | 2014-08-29 |
| CR20130657A (es) | 2014-05-16 |
| JP2018049033A (ja) | 2018-03-29 |
| WO2012167181A1 (en) | 2012-12-06 |
| AU2016244254B2 (en) | 2018-10-18 |
| AR086657A1 (es) | 2014-01-15 |
| ECSP13013092A (es) | 2014-08-29 |
| JP2016164578A (ja) | 2016-09-08 |
| US20140206017A1 (en) | 2014-07-24 |
| CN103946241A (zh) | 2014-07-23 |
| CO6940375A2 (es) | 2014-05-09 |
| BR112013030682A2 (pt) | 2016-12-06 |
| JP2014523521A (ja) | 2014-09-11 |
| IL229631A0 (en) | 2014-01-30 |
| ZA201308812B (en) | 2014-08-27 |
| TW201319572A (zh) | 2013-05-16 |
| NZ618682A (en) | 2016-04-29 |
| KR20140048156A (ko) | 2014-04-23 |
| MX2013013905A (es) | 2014-05-14 |
| UY34115A (es) | 2013-01-03 |
| US20120309020A1 (en) | 2012-12-06 |
| AU2012261883A1 (en) | 2013-05-02 |
| AP2013007285A0 (en) | 2013-11-30 |
| AU2016244254A1 (en) | 2016-11-03 |
| PE20141450A1 (es) | 2014-11-06 |
| EP2714744A1 (en) | 2014-04-09 |
| US20170269085A1 (en) | 2017-09-21 |
| CL2013003445A1 (es) | 2014-07-25 |
| MD20130098A2 (ro) | 2014-06-30 |
| MA35212B1 (fr) | 2014-06-02 |
| PH12013502490A1 (en) | 2014-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20200831 |