CN103930130B - 抗第三方中央型记忆t细胞、其产生方法以及其在移植和疾病治疗中的应用 - Google Patents

抗第三方中央型记忆t细胞、其产生方法以及其在移植和疾病治疗中的应用 Download PDF

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CN103930130B
CN103930130B CN201280054739.XA CN201280054739A CN103930130B CN 103930130 B CN103930130 B CN 103930130B CN 201280054739 A CN201280054739 A CN 201280054739A CN 103930130 B CN103930130 B CN 103930130B
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CN103930130A (zh
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亚伊尔·赖斯纳
亚基·艾德尔斯坦
埃兰·奥菲尔
阿萨夫·拉斯克
兰·阿菲克
诺加·奥-杰瓦
埃丝特·巴卡尔-卢斯蒂格
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Yeda Research and Development Co Ltd
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CN201280054739.XA 2011-09-08 2012-09-06 抗第三方中央型记忆t细胞、其产生方法以及其在移植和疾病治疗中的应用 Active CN103930130B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532172P 2011-09-08 2011-09-08
US61/532,172 2011-09-08
PCT/IL2012/050354 WO2013035099A1 (en) 2011-09-08 2012-09-06 Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

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CN103930130A CN103930130A (zh) 2014-07-16
CN103930130B true CN103930130B (zh) 2016-07-06

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US (3) US20140212398A1 (https=)
EP (1) EP2753351B1 (https=)
JP (1) JP6196620B2 (https=)
KR (1) KR102073901B1 (https=)
CN (1) CN103930130B (https=)
AU (1) AU2012305931B2 (https=)
BR (1) BR112014005355B1 (https=)
CA (1) CA2848121C (https=)
ES (1) ES2640813T3 (https=)
MX (1) MX351226B (https=)
RU (1) RU2636503C2 (https=)
SG (1) SG11201400513PA (https=)
WO (1) WO2013035099A1 (https=)
ZA (1) ZA201401993B (https=)

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US11844827B2 (en) 2015-07-16 2023-12-19 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy

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EP3101122B1 (en) 2009-08-24 2023-06-14 Baylor College of Medicine Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses
MX357746B (es) 2010-09-08 2018-07-23 Yeda Res And Development Co Ltd Star Uso de células t de memoria central anti-tercera parte para el tratamiento anti-leucemia/linfoma.
AU2012305931B2 (en) 2011-09-08 2017-09-07 Yeda Research And Development Co. Ltd Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment
CN104769104A (zh) 2011-12-12 2015-07-08 细胞药物有限公司 扩大t细胞的方法
GB201121308D0 (en) 2011-12-12 2012-01-25 Cell Medica Ltd Process
PT2812431T (pt) 2012-02-09 2019-10-18 Baylor College Medicine Pepmixes para gerar ctls multivirais com larga especifidade
CN104411819B (zh) * 2012-06-11 2019-05-10 威尔逊沃夫制造公司 用于过继细胞疗法的改进的细胞培养方法
SG11201708516YA (en) * 2015-04-17 2017-11-29 David Maxwell Barrett Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
CN104946588A (zh) * 2015-07-07 2015-09-30 英普乐孚生物技术(上海)有限公司 一种抗原特异性t淋巴细胞的分离和高效扩增培养方法
AU2016297014B2 (en) 2015-07-21 2021-06-17 Novartis Ag Methods for improving the efficacy and expansion of immune cells
JP6999941B2 (ja) 2015-09-18 2022-02-10 ベイラー カレッジ オブ メディスン 病原体からの免疫原性抗原同定および臨床的有効性との相関
US10691773B2 (en) 2015-12-30 2020-06-23 General Electric Company Cell processing techniques
JP7185530B2 (ja) 2016-06-13 2022-12-07 トルク セラピューティクス， インコーポレイテッド 免疫細胞機能を促進するための方法および組成物
KR20190033066A (ko) * 2016-06-24 2019-03-28 맥마스터 유니버시티 입양 세포 전달 및 종양붕괴 바이러스 병용 치료
MX2019000022A (es) * 2016-06-27 2019-09-18 Yeda Res & Dev Células veto generadas a partir de linfocitos t de memoria.
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
CN110392736A (zh) * 2017-01-18 2019-10-29 耶达研究及发展有限公司 遗传修饰的反抑细胞及其在免疫治疗中的用途
EP3572502B1 (en) * 2017-01-20 2023-01-11 Kyoto University Method for producing cd8alpha +beta + cytotoxic t cells
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JP7285828B2 (ja) 2017-09-05 2023-06-02 トルク セラピューティクス， インコーポレイテッド 治療用タンパク質組成物ならびにその作製および使用方法
AU2018337960B2 (en) * 2017-09-20 2025-08-14 Neximmune, Inc. Cell compositions comprising antigen-specific T cells for adoptive therapy
CN108165529B (zh) * 2017-12-28 2021-07-16 北昊干细胞与再生医学研究院有限公司 中枢记忆性t细胞体及其外培养方法
CN111801104A (zh) * 2018-02-06 2020-10-20 西雅图儿童医院（Dba西雅图儿童研究所） Car-t细胞的封闭系统制造过程
EP3809983B1 (en) 2018-06-22 2025-08-27 Mayo Foundation for Medical Education and Research Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionality
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