CN103893608A - Compound Chinese herbal medicine preparation for preventing and treating animal cold in summer - Google Patents
Compound Chinese herbal medicine preparation for preventing and treating animal cold in summer Download PDFInfo
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- CN103893608A CN103893608A CN201410161666.5A CN201410161666A CN103893608A CN 103893608 A CN103893608 A CN 103893608A CN 201410161666 A CN201410161666 A CN 201410161666A CN 103893608 A CN103893608 A CN 103893608A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a compound Chinese herbal medicine preparation for preventing and treating animal cold in summer. The compound Chinese herbal medicine preparation for preventing and treating animal cold in summer, which is provided by the invention, is mainly prepared from coptis chinensis ash. According to the technical scheme provided by the invention, the compound Chinese herbal medicine preparation for preventing and treating animal cold in summer is prepared from the following Chinese herbal medicines in percentage by weight: 10-50% of coptis chinensis ash, 10-30% of agastache rugosus, hyacinth beans, solanum cathayanum, radix bupleurim or honeysuckle stems, 10-30% of artemisia apiacea, mint, rhizoma phragmitis or rhizoma phragmitis and the balance of folium mori, bamboo leaves, negundo chastetree leaves or lotus leaves. The invention further provides a preparation method of the Chinese herbal medicine preparation. The invention further provides a method of preventing animal cold in summer by using the compound Chinese herbal medicine preparation. The compound Chinese herbal medicine preparation provided by the invention can be used for preventing and treating animal cold in summer.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to the Chinese medicine formula of a kind of prevention and treatment animal flu in summer.
Background technology
The serious disease of harm domestic animal, can be divided into common disorder and infectious disease according to the cause of disease.Common disorder is that bad climate causes, to catch a cold as representative; Infectious disease is that pathogen causes, taking infectiousness pneumonia as representative.Flu is primary disease, and the inflammation of infection is secondary disease; Control is liable to colds, and has has also just prevented and treated infectious disease simultaneously.According to the anti-statistics of beast: the sickness rate of flu and complication thereof can account for 85% of livestock disease total amount, is common, the most multiple disease.Therefore, domestic animal epidemic prevention, should pick up from " flu ".
Theory of Chinese medical science is thought, catches a cold due to 4 o'clock main gas differences, is subject to heresy different, therefore its character also has difference, emits heat-damp in summer summer more.Syndrome of summer-heat-dampness symptom is heating, fever not subsiding after sweating, the turbid tears of nasal obstruction stream, dizzy and headache, heavy sensation of the body asthenia, restlessness and thirst, chocking sensation in the chest and nausea, short urination, yellowish fur, soft and rapid pulse.Summer heat-dampness outer be because heat-damp in summer combined pathogens, invades body and affect the transporting of spleen through mouth and nose, fur.Control and should clearing away summer-heat damp eliminating induce sweat.
In the southern area of China, summer, temperature raise (adding high humidity), animal breath difficulty, and metabolism is slowed down, and resistance declines; Animal is " flu " easily, and then causes various secondary diseases, causes the situation including dead to occur, causes raiser's economic loss.Summer, flu was commonly encountered diseases.Although western medicine and medical practitioners has the effect for the treatment of flu, there is no the effect of preventing cold.Different from Western medicine is that Chinese medicine not only can also can be treated flu by preventing cold.Aspect prophylactic, Chinese medicine has very significantly advantage.The feature of summer climate is " high temperature " and " high humidity ", and Chinese medicine has the function of " clearing away summer-heat " and " dehumidifying ": some Chinese medicine (heat clearing away class) can regulate the body temperature of animal, adjusts the adaptability of animal and environment; Some Chinese medicine has the function of " damp eliminating ", can regulate the inside and outside balance of animal body.Utilize the compound recipe of Chinese medicines composition that these have difference in functionality, there is heat clearing away, removing heat from blood simultaneously, dry, the function such as diaphoresis, fairly obvious for prevention and the treatment animal effect of catching a cold summer.
Rhizoma Coptidis is cold in nature, bitter in the mouth, has the function of heat clearing and damp drying, eliminating fire and detoxication, is the traditional Chinese medicine of China.In Traditional Chinese Medicine Chinese medicine, Rhizoma Coptidis is usually used as preparing the Chinese patent medicine of various heat-clearing and toxic substances removing.Rhizoma Coptidis lime-ash is after Rhizoma Coptidis " hair lump " (with the Rhizoma Coptidis fresh goods of Rhizoma Coptidis, petiole, skin and silt etc.) is dried, in the process of " playing groove cage " (removing Rhizoma Coptidis, petiole, epidermis and silt etc.), and the garbage removing.Up to the present, the exploitation of Rhizoma Coptidis lime-ash there is not yet report.At present, the Chinese medicine that has prevention and treatment people to catch a cold summer, such as " the positive gas-liquid of Radix agastaches " (Rhizoma Atractylodis Pericarpium Citri Reticulatae Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) Radix Angelicae Dahuricae Poria Pericarpium Arecae Rhizoma Pinelliae Radix Glycyrrhizae extractum patchouli oil Folium perillae acutae oil) and " abrotanum cold-treating preparation " (Herba Moslae, Cortex Magnoliae Officinalis, Herba Artemisiae Annuae, Radix Scutellariae) (Han Liang, the preclinical study of abrotanum cold-treating preparation, Traditional Chinese Medicine University Of Guangzhou, 2006, Master's thesis) etc., use Rhizoma Coptidis lime-ash as primary raw material but there is not yet, the prevention of exploitation and the technology for the treatment of flu in summer and the report of product.
Summary of the invention
The technical problem to be solved in the present invention is the Chinese herbal compound preparation for a kind of prevention taking Rhizoma Coptidis lime-ash as primary raw material and treatment animal flu in summer.
Technical scheme of the present invention is the Chinese herbal compound preparation of a kind of prevention and treatment animal flu in summer, Chinese herbal medicine by following percentage by weight is made: Rhizoma Coptidis lime-ash 10～50%, Herba Pogostemonis, Seem Lablab Album, Solanum lyratum Thunb., Radix Bupleuri or vine of Flos Lonicerae 10～30%, Herba Artemisiae Annuae, Herba Menthae, Rhizoma Phragmitis or Flos Chrysanthemi 10～30%, surplus is Folium Mori, Folium Bambusae, Folium Viticis Negundo or Folium Nelumbinis.
Preferably, the consumption of Rhizoma Coptidis lime-ash is 20～25%.
Preferably, each raw material weight percentage ratio of Chinese herbal compound preparation of the present invention is as follows: Rhizoma Coptidis lime-ash 30%, Herba Pogostemonis 30%, Herba Artemisiae Annuae 20%, Folium Mori 20%.
Preferably, each raw material weight percentage ratio of Chinese herbal compound preparation of the present invention is as follows: Rhizoma Coptidis lime-ash 30%, Flos Lonicerae rise 30%, Flos Chrysanthemi 20%, Folium Nelumbinis 20%.
The present invention also provides the preparation method of described Chinese herbal compound preparation, comprise the steps: to take Rhizoma Coptidis lime-ash 10～50% according to following weight proportioning, Herba Pogostemonis, Seem Lablab Album, Solanum lyratum Thunb., Radix Bupleuri or vine of Flos Lonicerae 10～30%, Herba Artemisiae Annuae, Herba Menthae, Rhizoma Phragmitis or Flos Chrysanthemi 10～30%, surplus is Folium Mori, Folium Bambusae, Folium Viticis Negundo or Folium Nelumbinis; Mix, be then crushed to 5～100 orders, packaging.
The present invention also provides the method that uses described Chinese herbal compound preparation prevention animal flu in summer, specific as follows: according to the addition of 0.1～1 gram of per kilogram the weight of animals, to add in feedstuff, connect and feed 5～10 days.
The present invention also provides the method that uses described Chinese herbal compound preparation treatment animal flu in summer, specific as follows: according to the addition of 0.3～3 gram of per kilogram the weight of animals, to add in animal feed, connect and feed 2～5 days.
Rhizoma Coptidis lime-ash is mainly made up of Rhizoma Coptidis, Rhizoma Coptidis petiole and/or Rhizoma Coptidis epidermis etc.Result of study shows: Rhizoma Coptidis contains 2～4% total alkaloids, and stem contains 1～3% total alkaloids; The palpus of close Rhizoma Coptidis and the contained alkaloid of stem are apparently higher than the palpus away from Rhizoma Coptidis and stem, and its value is higher; Rhizoma Coptidis and stem near Rhizoma Coptidis enter Rhizoma Coptidis lime-ash in the course of processing.Rhizoma Coptidis lime-ash contains and active component like Rhizoma Coptidis, has and pharmacological function like Rhizoma Coptidis.Up to the present, the exploitation of Rhizoma Coptidis lime-ash there is not yet report.Utilize Rhizoma Coptidis lime-ash to there is the Chinese herb compound of very strong " heat clearing away " and " damp eliminating " functional development prevention and treatment animal flu in summer, not only can bring into play the effect of preventing and curing diseases, and cost is extremely low, there is the unexistent superiority of doctor trained in Western medicine and Western medicine.
Theory of Chinese medical science is thought, emits summer due to heat-damp in summer more, and prevention and treatment animal flu in summer (summer-heat damp cold) should be induced sweat in clearing away summer-heat damp eliminating.In compound recipe of the present invention, Rhizoma Coptidis lime-ash is cold in nature, bitter in the mouth, has the function of heat clearing away, dampness, pathogenic fire purging, removing toxic substances, is our monarch drug, plays " heat clearing away (clearing away summer-heat) " and " damp eliminating ".
Herba Pogostemonis, acrid in the mouth, slightly warm in nature, return lung, spleen, stomach warp, and there is driving away summer heat, induce sweat, effect of removing dampness to restore normal function of the stomach, be our ministerial drug, play " heat clearing away (clearing away summer-heat) " and " inducing sweat ".Seem Lablab Album is sweet, flat, enter spleen, stomach warp, have spleen invigorating and in, effect of the removing dampness of relieving summer heat; Solanum lyratum Thunb. hardship, cool, returns liver, gallbladder, lung, large intestine, urinary bladder channel, has the effect anticancer, clearing away heat-damp and promoting diuresis that relieves internal heat; Radix Bupleuri bitter in the mouth, cold nature, return liver, gallbladder meridian, has the effects such as reconciling superficies and interior, soothing the liver, yang invigorating; Vine of Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has effect of heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treatment wind.As can be seen here, Herba Pogostemonis, Seem Lablab Album, Solanum lyratum Thunb., Radix Bupleuri or vine of Flos Lonicerae have similar effect, in we, can mutually replace use.
Herba Artemisiae Annuae, bitter in the mouth, pungent, cold in nature, return liver, gallbladder meridian, there is the effect of heat clearing away, expelling summer-heat, be our ministerial drug, play " heat clearing away (clearing away summer-heat) ".Herba Menthae property is pungent, cool, enters lung meridian, Liver Channel, has dispelling wind, dispels the heat, wards off effect dirty, removing toxic substances; Rhizoma Phragmitis is sweet, cold, return lung meridian, stomach warp, there is heat clearing away, promote the production of body fluid, effect of relieving restlessness, preventing or arresting vomiting; Flos Chrysanthemi is sweet, bitter, be slightly cold, and returns lung, Liver Channel, has effect of loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.The effect of Herba Artemisiae Annuae, Herba Menthae, Rhizoma Phragmitis or Flos Chrysanthemi is similar, in we, can exchange use.
Folium Mori, sweet in the mouth, hardship, cold in nature, return lung, Liver Channel, there is the effect of dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, be our ministerial drug, play " heat clearing away (clearing away summer-heat) ".Folium Bambusae sweet in the mouth, light, cold in nature, return stomach warp, heart channel, lung meridian, there is clearing heat and relieving fidgetness; Promote the production of body fluid effect of diuresis; Folium Viticis Negundo acrid in the mouth, hardship, cool in nature, return lung, liver, small intestine meridian, there is the effects such as the heat radiation of inducing sweat, removing dampness for regulating stomach, killing parasites for relieving itching; Folium Nelumbinis bitter in the mouth, property is flat, returns stomach warp, spleen channel, Liver Channel, has effect of clearing away summer-heat, sending up the lucid YANG, dissipating blood stasis hemostasis.Folium Mori, Folium Bambusae, Folium Viticis Negundo or Folium Nelumbinis have similar effect, in we, can exchange use.
Beneficial effect of the present invention: the present invention is taking Rhizoma Coptidis lime-ash as primary raw material, make full use of the functions such as the heat clearing and damp drying, eliminating fire and detoxication of Rhizoma Coptidis lime-ash, antibacterial and antiviral, be aided with other Chinese medicine, the compound Chinese herb product of the prevention of exploitation and treatment animal flu in summer, has the clinical effectiveness of significant prevention and treatment animal flu in summer.The primary raw material Rhizoma Coptidis lime-ash of this product is twice laid, has the advantage that cost is low, has improved the utilization rate of resource simultaneously, has broad application prospects.
Detailed description of the invention
The preparation of embodiment 1 medicine of the present invention
10 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms of Herba Pogostemoniss, 30 kilograms of Herba Artemisiae Annuaes, 30 kilograms, Folium Mori, after mix homogeneously, be crushed to 5 orders, is divided into 10 kilograms of one bag of packagings, for subsequent use.While being used for preventing animal to catch a cold summer, according to 1 gram of interpolation of per kilogram, use continuously 5 days, there is the good prevention effect of catching a cold summer; While being used for the treatment of the animal that flu occurs, according to 3 grams of interpolations of per kilogram, use continuously 2 days, can cure the flu in summer of animal.
The preparation of embodiment 2 medicines of the present invention
50 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms, Seem Lablab Album, 10 kilograms of Herba Menthaes, 10 kilograms, Folium Bambusae, after mix homogeneously, be crushed to 100 orders, is divided into 10 kilograms of one bag of packagings, for subsequent use.While being used for preventing animal to catch a cold summer, according to 0.1 gram of interpolation of per kilogram, use continuously 10 days, there is the good prevention effect of catching a cold summer; While being used for the treatment of the animal that flu occurs, according to 0.3 gram of interpolation of per kilogram, use continuously 5 days, can cure the flu in summer of animal.
The preparation of embodiment 3 medicines of the present invention
30 kilograms of Rhizoma Coptidis lime-ash, 10 kilograms of Solanum lyratum Thunb., 30 kilograms of Rhizoma Phragmitiss, 30 kilograms of Folium Viticis Negundos, after mix homogeneously, be crushed to 50 orders, is divided into 10 kilograms of one bag of packagings, for subsequent use.While being used for preventing animal to catch a cold summer, according to 0.5 gram of interpolation of per kilogram, use continuously 7 days, there is the good prevention effect of catching a cold summer; While being used for the treatment of the animal that flu occurs, according to 1 gram of interpolation of per kilogram, use continuously 3 days, can cure the flu in summer of animal.
The preparation of embodiment 4 medicines of the present invention
40 kilograms of Rhizoma Coptidis lime-ash, 20 kilograms of Radix Bupleuri, 20 kilograms of Flos Chrysanthemis, 20 kilograms, Folium Nelumbinis, after mix homogeneously, be crushed to 20 orders, is divided into 10 kilograms of one bag of packagings, for subsequent use.While being used for preventing animal to catch a cold summer, according to 0.3 gram of interpolation of per kilogram, use continuously 8 days, there is the good prevention effect of catching a cold summer; While being used for the treatment of the animal that flu occurs, according to 0.5 gram of interpolation of per kilogram, use continuously 5 days, can cure the flu in summer of animal.
The preparation of embodiment 5 medicines of the present invention
25 kilograms of Rhizoma Coptidis lime-ash, Flos Lonicerae rise 30 kilograms, 25 kilograms of Herba Artemisiae Annuaes, 20 kilograms, Folium Nelumbinis, after mix homogeneously, are crushed to 10 orders, are divided into 10 kilograms of one bag of packagings, for subsequent use.While being used for preventing animal to catch a cold summer, according to 0.5 gram of interpolation of per kilogram, use continuously 7 days, there is the good prevention effect of catching a cold summer; While being used for the treatment of the animal that flu occurs, according to 1 gram of interpolation of per kilogram, use continuously 5 days, can cure the flu in summer of animal.
The effect test of embodiment 6 medicines of the present invention
The preparation of medicine 1: 30 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms of Herba Pogostemoniss, 20 kilograms of Herba Artemisiae Annuaes, 20 kilograms, Folium Mori, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of medicine 2: 30 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms, Seem Lablab Album, 20 kilograms of Herba Menthaes, 20 kilograms, Folium Bambusae, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of medicine 3: 30 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms of Solanum lyratum Thunb., 20 kilograms of Rhizoma Phragmitiss, 20 kilograms of Folium Viticis Negundos, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of medicine 4: 30 kilograms of Rhizoma Coptidis lime-ash, Flos Lonicerae rise 30 kilograms, 20 kilograms of Flos Chrysanthemis, 20 kilograms, Folium Nelumbinis, after mix homogeneously, are crushed to 20 orders, are divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of control drug 1: 100 kilograms of Rhizoma Coptidis lime-ash, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of control drug 2: 50 kilograms of Rhizoma Coptidis lime-ash, 50 kilograms of Herba Pogostemoniss, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The preparation of control drug 3:: 40 kilograms of Rhizoma Coptidis lime-ash, 30 kilograms of Herba Pogostemoniss, 30 kilograms of Herba Artemisiae Annuaes, after mix homogeneously, be crushed to 20 orders, be divided into 10 kilograms of one bag of packagings, for subsequent use.
The dead experiment of prevention rabbit flu in summer: tested July 15 and start to carry out, select 240 rabbits to carry out experimentation, blank group (not administration) 30,210 of medicine groups (30 every group).According to the dosage of 0.5 gram of per kilogram rabbit body weight administration, feed continuously drug withdrawal in 5 days 5 days, rechallenge drug withdrawal in 5 days 5 days, until 30 days; After administration 15 days, to rabbit-hutch water spray and blowing cooling 2 hours (manufacturing flu environment).Matched group is raised under same environment and condition, not administration.To the sick and dead result of statistics rabbit on August 15, in table 1.
The dead experiment for the treatment of rabbit flu in summer: test during 15～August 15 July and carry out, choose 240 of sick rabbits (sneeze, body temperature exceed 38 DEG C, often minimizing, lethargy of feed) that developed signs of a cold and carry out experimentation, blank group (not administration) 30,210 of medicine groups (30 every group).According to the dosage of 2 grams of per kilogram rabbit body weight administrations, feed continuously 3 days.Matched group is raised under same environment and condition, not administration.To the dead result of statistics rabbit on August 15 and rehabilitation result, in table 1.
The result of use of table 1 medicine of the present invention
Experimental result shows, the Chinese herb compound product of this prevention and treatment animal flu in summer has very significantly prevention and the treatment rabbit dead effect of catching a cold summer: only use Rhizoma Coptidis lime-ash, the dead effect of catching a cold summer of existing obvious prevention and treatment rabbit; The compound recipe of two herbal medicine compositions, successful strengthens; The compound recipe of three taste medical material compositions, better effects if; The compound recipe of four Chinese medicine material composition, the effect of prevention and treatment animal in summer flu is ideal.
Claims (7)
1. one kind is prevented and treats the Chinese herbal compound preparation of animal flu in summer, it is characterized in that: the Chinese herbal medicine by following percentage by weight is made: Rhizoma Coptidis lime-ash 10～50%, Herba Pogostemonis, Seem Lablab Album, Solanum lyratum Thunb., Radix Bupleuri or vine of Flos Lonicerae 10～30%, Herba Artemisiae Annuae, Herba Menthae, Rhizoma Phragmitis or Flos Chrysanthemi 10～30%, surplus is Folium Mori, Folium Bambusae, Folium Viticis Negundo or Folium Nelumbinis.
2. the Chinese herbal compound preparation of prevention as claimed in claim 1 and treatment animal flu in summer, is characterized in that: the consumption of Rhizoma Coptidis lime-ash is 20～25%.
3. the Chinese herbal compound preparation of prevention as claimed in claim 1 or 2 and treatment animal flu in summer, is characterized in that: each raw material weight percentage ratio of described Chinese herbal compound preparation is as follows: Rhizoma Coptidis lime-ash 30%, Herba Pogostemonis 30%, Herba Artemisiae Annuae 20%, Folium Mori 20%.
4. the Chinese herbal compound preparation of the prevention as described in claim 1～3 any one and treatment flu in animal summer, is characterized in that: each raw material weight percentage ratio of this described Chinese herbal compound preparation is as follows: Rhizoma Coptidis lime-ash 30%, Flos Lonicerae rise 30%, Flos Chrysanthemi 20%, Folium Nelumbinis 20%.
5. the preparation method of Chinese herbal compound preparation described in claim 1～4 any one, it is characterized in that: comprise the steps: to take Rhizoma Coptidis lime-ash 10～50% according to following weight proportioning, Herba Pogostemonis, Seem Lablab Album, Solanum lyratum Thunb., Radix Bupleuri or vine of Flos Lonicerae 10～30%, Herba Artemisiae Annuae, Herba Menthae, Rhizoma Phragmitis or Flos Chrysanthemi 10～30%, surplus is Folium Mori, Folium Bambusae, Folium Viticis Negundo or Folium Nelumbinis; Mix, be then crushed to 5～100 orders, packaging.
6. the method for Chinese herbal compound preparation prevention animal flu in summer described in right to use requirement 1～4 any one, is characterized in that: specific as follows: according to the addition of 0.1～1 gram of per kilogram the weight of animals, add in feedstuff, connect and feed 5～10 days.
7. the method for Chinese herbal compound preparation treatment animal flu in summer described in right to use requirement 1～4 any one, is characterized in that: specific as follows: according to the addition of 0.3～3 gram of per kilogram the weight of animals, add in animal feed, connect and feed 2～5 days.
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