A kind of anti-chicken high-temperature hot stress compound Chinese herb formula and application
Technical field
The present invention relates to animal compound Chinese medicine formula technical field, particularly relate to a kind of anti-chicken high-temperature hot stress compound Chinese herb formula and application, this Chinese herbal medicine formula is applicable to control laying hen and broiler thermal stress reaction.
Background technology
Heat stress refers to the syndrome causing laying hen, the reduction of broiler feed intake, fertility performance decline, dead mortality to rise because of hot environment.When temperature is more than 25 DEG C, will there is heat stress in chicken, temperature is higher, stress degree larger.The heat stress harm laying hen of sustainable existence and broiler breeding industry, appetite declines, laying rate declines, dead mortality increases, management difficulty increases, economic benefit declines to a great extent to cause chicken to be mined massively.In extreme circumstances, feed intake fall can reach 20%, and laying rate of laying hen fall can reach 50%, and the mortality rate of broiler can reach 5-30%.
Usually through strengthening physics cooling measure and improving feeding and management in production practices, the method particularly change feed nutrition concentration, converting feeding time, add soiling, for alleviating the heat stress of chicken, this class methods specificity is not strong, effect is not satisfactory, and adds management difficulty.Use vitamin and electrolyte to make an addition in feedstuff or drinking-water, support the use wet curtain and add aeration-cooling way and carry out hen house cooling, but be difficult to gather effect when temperature is more than 30 DEG C.
Utilize Chinese herbal medicine formula to control the heat stress of chicken, laying hen can be solved more up hill and dale, negative effect that broiler heat stress causes, efficiently and effectively improves breeding layer chicken benefit, for Implement Green Food production and supplyment lays a good foundation.This compound Chinese herb formula embodies in clinical practice that action effect is obvious, acting duration is long, side effect is little, the feature of high financial profit, is safety, green, Chinese herbal medicine formula efficiently.
Summary of the invention
For the deficiencies in the prior art, the present invention aim to provide a kind of anti-chicken high-temperature hot stress compound Chinese herb formula and application, by selecting suitable medical material and proportioning thereof and formulating the preparation method of its patent medicine, reach the effect of the negative effect alleviating laying hen and broiler heat stress safely and effectively, and make it be applicable to apply clinically.
In order to achieve the above object, the present invention is by the following technical solutions:
Anti-chicken high-temperature hot stress a compound Chinese herb formula, be prepared from by following seven taste Chinese crude drugs:
Herba Pogostemonis, pungent, tepor.Enter spleen, stomach, lung meridian.There is removing dampness by means of aromatics, relieving pain by regulating middle-JIAO, separate pathogenic factor in the exterior, except effect of humidity hysteresis.For the disease of the tripe distention and fullness in the abdomen of turbid damp internal resistance, the spleen being blocked by dampness, transporting imbalance, few food, asthenia.Can also be fallen apart pathogenic factor in the exterior, is used for the treatment of flu and accompanies the syndrome of humidity hysteresis.Pharmacological research confirms, the aromatic odor of Herba Pogostemonis has promotion gastric secretion with digestant effect.
Folium Mori, bitter, sweet, cold.Enter lung, Liver Channel.There is effect of wind-dispelling heat-dissipating, liver heat removing and eyesight improving.Be used for the treatment of and show in wind heat and let out lung-heat, to cards such as affection due to external wind and heat effectively.Pharmacological research confirms, Folium Mori have antipyretic, expectorant, diuresis, has positive role to the discomfort that alleviation heat stress causes.
Herba Eupatorii, pungent, flat.Enter spleen channel.There is removing dampness of being amusing, effect that expelling summer-heat promotes the production of body fluid.Strongly fragrant in the tripe distention and fullness in the abdomen caused by middle Jiao, white and greasy fur and heat-damp in summer exterior syndrome for damp and hot turbid pathogen.Also kindly separate summer-heat and promote the production of body fluid, for accumulateing in summer-heat, the syndrome of tripe distention and fullness in the abdomen.Pharmacological research confirms, the effect that Herba Eupatorii has facilitating digestion liquid to secrete, and causes the heat stress of chicken and few food of causing has positive mitigation to summer-heat.
Herba Moslae, pungent, tepor.Enter lung, spleen, stomach warp.There is effect of diaphoresis expelling summer-heat, dispelling dampness and promoting diuresis.Heatstroke for horse, cattle is treated.Pharmacological research confirms, Herba Moslae has diaphoresis, antipyretic, diuresis.
Herba Artemisiae Annuae, bitter, cold.Enter liver, gallbladder meridian.There is clearing away summer-heat, effect of reducing the asthenic fever.Herba Artemisiae Annuae fragrant odour, though the cold and not imapirment of the spleen and stomach of sweetness and bitterness, and has the effect of removing summer-heat pathogenic summer-heat, clearing heat and eliminating dampness, is used for the treatment of the disease of diseases caused by exogenous pathogenic factor summer-heat.
Gypsum Fibrosum, pungent, sweet, Great Cold.Enter lung, stomach warp.Have powerful clearing away heat-fire effect, kind clearing heat in QI system divides excess-heat.For the large heat of lung stomach, the high Sheng card of the excess-heat such as hyperpyrexia.Pharmacological research confirms, Gypsum Fibrosum can suppress heating maincenter and play refrigeration function.
The Rhizoma Atractylodis Macrocephalae, sweet, bitter, warm.Enter spleen, stomach warp.There is effect of invigorating the spleen and replenishing QI, dampness diuretic, strengthening superficial resistance to stop perspiration.For lack of appetite distension, fatigue and weakness etc. caused by deficiency of spleen-QI and stomach-QI, dysfunction of the spleen in transportation and transformation.Pharmacological research confirms, the Rhizoma Atractylodis Macrocephalae is containing volatile oil, and in oil, Main Ingredients and Appearance is atractylol and atractylone, and containing vitamin A sample material, has positive role to promotion gastrointestinal peristalsis.
Described anti-chicken high-temperature hot stress compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content:
Preferably, described anti-chicken high-temperature hot stress compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content:
Best, described anti-chicken high-temperature hot stress compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content:
The anti-chicken high-temperature hot of above-mentioned each formula stress the step of preparation method of compound Chinese herb as follows:
Take each Chinese crude drug, pulverize through pulverizer respectively, by described formula proportion, each Chinese crude drug is mixed after crossing 80 mesh sieves, be sealed in the plastic bag of good airproof performance for subsequent use.
Technical solution of the present invention to each ingredient requirement is: the water content of each raw materials of traditional Chinese medicinal materials is lower than 12%, and impurity content is lower than 0.5%.
The present invention is according to Chinese veterinarian's medicine theory, in conjunction with Chinese herbal medicine meridian distribution of property and flavor and efficacy effect feature, when based on the pathogeny of the heat stress that correct dialectical laying hen and broiler are caused because of high ambient temperature, with the Principles and measurements of Chinese veterinarian's prescription prescription, according to monarch, minister, the rigorous formula such as relation, seven emotions compatibility of helping, making, make it divide the work clearly, Each performs its own functions; In a large amount of clinical trial, screen a kind of alleviate laying hen and the negative effect of broiler heat stress compound Chinese herb formula and application one by one simultaneously.The result that pharmacological action of the present invention: understand according to the dialectical theoretical principle of Chinese veterinarian, laying hen and broiler heat stress belong to clinically holds summer-heat wetness type damp-heat syndrome under the arm is wet tired spleen, heat disturbs god.In formula of the present invention, Herba Pogostemonis and Folium Mori are monarchs drug, have removing dampness by means of aromatics, relieving pain by regulating middle-JIAO, separate pathogenic factor in the exterior, except effect of humidity hysteresis, for the negative effect of the heat stress of full relief chicken plays a crucial role; Gypsum Fibrosum, Herba Artemisiae Annuae, Herba Eupatorii, Herba Moslae, the Rhizoma Atractylodis Macrocephalae are ministerial drug, and strengthening monarch drug is amusing effect of appetizing, the heat clearing away of Eradicates summer-heat, dispelling dampness and promoting diuresis, jointly assist monarch drug to complete to drive the effect that summer-heat is antipyretic, rouse oneself taste, a surname's body healthy energy.
Compared with prior art, advantage of the present invention is:
1, anti-chicken high-temperature hot provided by the present invention stress compound Chinese herb, can effectively alleviate the negative effect that in current laying hen and broiler production, heat stress syndrome group brings, be a kind of Chinese medicine formula product of safe, novel, Effective Anti chicken heat shock;
2, anti-chicken high-temperature hot provided by the present invention stress compound Chinese herb, be made up of natural Chinese medicine completely, without special processing procedure, the course of processing is extremely simple, ecosystem, all-natural product, for production safety, ecology, green Quality eggs and Carnis Gallus domesticus lay the foundation;
3, anti-chicken high-temperature hot provided by the present invention stress compound Chinese herb, showing that consumption is little, the feature of instant effect, effect stability after application aborning, is a kind of desirable Chinese herbal medicine formula product.
Detailed description of the invention
In order to make those skilled in the art understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.But following content should not be understood to the restriction to claims of the present invention request protection domain in any degree.
In following examples 1,2,3,4, Hubei, the Chinese crude drug Gypsum Fibrosum place of production used, Guangdong, the Herba Pogostemonis place of production, the place of production of Herba Artemisiae Annuae, Herba Eupatorii, Folium Mori, the Rhizoma Atractylodis Macrocephalae, Herba Moslae is Anhui.The water content of each raw materials of traditional Chinese medicinal materials is lower than 12%, and impurity content is lower than 0.5%.
Anti-chicken high-temperature hot stress a compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content: Folium Mori, 20%; Herba Pogostemonis, 29%; Gypsum Fibrosum, 10%; Herba Artemisiae Annuae, 10%; Herba Eupatorii, 15%; The Rhizoma Atractylodis Macrocephalae, 8%; Herba Moslae, 8%.
Above-mentioned each Chinese crude drug is pulverized through pulverizer respectively, mixes by the ratio of the required after crossing 80 mesh sieves, be sealed in the plastic bag of good airproof performance for subsequent use.
Embodiment 2
Anti-chicken high-temperature hot stress a compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content: Folium Mori, 20%; Herba Pogostemonis, 35%; Gypsum Fibrosum, 10%; Herba Artemisiae Annuae, 10%; Herba Eupatorii, 15%; The Rhizoma Atractylodis Macrocephalae, 5%; Herba Moslae, 5%.
Above-mentioned each Chinese crude drug is pulverized through pulverizer respectively, mixes by the ratio of the required after crossing 80 mesh sieves, be sealed in the plastic bag of good airproof performance for subsequent use.
Embodiment 3
Anti-chicken high-temperature hot stress a compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content: Folium Mori, 18%; Herba Pogostemonis, 30%; Gypsum Fibrosum, 10%; Herba Artemisiae Annuae, 10%; Herba Eupatorii, 12%; The Rhizoma Atractylodis Macrocephalae, 10%; Herba Moslae, 10%.
Above-mentioned each Chinese crude drug is pulverized through pulverizer respectively, mixes by the ratio of the required after crossing 80 mesh sieves, be sealed in the plastic bag of good airproof performance for subsequent use.
Embodiment 4
Anti-chicken high-temperature hot stress a compound Chinese herb formula, be made up of the traditional Chinese medicinal material raw materials of following weight percent content: Folium Mori, 15%; Herba Pogostemonis, 25%; Gypsum Fibrosum, 10%; Herba Artemisiae Annuae, 10%; Herba Eupatorii, 10%; The Rhizoma Atractylodis Macrocephalae, 15%; Herba Moslae, 15%.
Above-mentioned each Chinese crude drug is pulverized through pulverizer respectively, mixes by the ratio of the required after crossing 80 mesh sieves, be sealed in the plastic bag of good airproof performance for subsequent use.
In order to determine that optimal drug proportioning combines, invention has been clinical effect trial, carrying out checking and illustrating:
Test 1
The basic condition of test:
Test period is on August 22,22 days to 2014 July in 2014, and place is Xinzhou District, Wuhan City Wang Ji Qin Ye company, and temperature on average was 33 DEG C at that time.Select 150 ages in days from cultivating the assorted laying hen 16000 of soil, wherein test chicken 8000 be divided into 4 groups, each 2000 of every group because there being 4 kinds of pharmaceutical formulations, contrast chicken 8000, raise in same hen house, freely ventilate, staged is raised in cages raising, freely drinks water, artificial to feed material, day feeds 2 times, and feed it is clean for degree to eat with feedstuff in crib at every turn, has residue then to carry out cleaning and counting in the feedstuff of not feeding.Every day, institute's feed material was responsible for by special messenger, and performed food consumption record the same day.
Observation of curative effect:
Direct-fed in feedstuff admixed by medicine, and dosage accounts for 1% of complete feedstuff quality.The amplitude, dead mortality fall, the laying rate increase rate that increase with the feed intake of chicken group after dispensing, broken rate of eggshell fall is for judgment basis, carry out the calculating of efficiency index afterwards according to indices weight aborning, formula is as follows: the dead mortality fall × 15%+ laying rate increase rate × 15%+ broken rate of eggshell fall × 10%=efficiency index of the amplitude that feed intake increases × 60%+.
Each group of therapeutic effect is in table 1:
Table 1
The efficiency index of herbal mixture prepared by the present invention's four embodiments is maximum with the value of embodiment 1, the difference respectively organized with other is extremely remarkable, and its feed intake increasing degree is more than more than 10% simultaneously, and anti-heat stress of layer effect is obvious, there is clinical value, be defined as optimum proportioning combination.
In order to verify that the present invention is in conjunction with clinical therapeutic efficacy further, carry out verification experimental verification further
Test 2
The basic condition of test:
Test period is on August 22,22 days to 2014 July in 2014, and place is Xinzhou District, Wuhan City Li Ji Qin Ye company, and temperature on average was 33 DEG C at that time.Select 380 age in days Roman egghen 20000, wherein test chicken 10000 be divided into 4 groups, each 2500 of every group because there being 4 kinds of pharmaceutical formulations, contrast chicken 10000, raise in adjacent two hen houses, freely ventilate, staged is raised in cages raising, freely drinks water, artificial to feed material, day feeds 2 times, and feed it is clean for degree to eat with feedstuff in crib at every turn, has residue then to carry out cleaning and counting in the feedstuff of not feeding.Every day, institute's feed material was responsible for by special messenger, and performed food consumption record the same day.
Observation of curative effect:
Direct-fed in feedstuff admixed by medicine, and dosage accounts for 1% of complete feedstuff quality.The amplitude, dead mortality fall, the laying rate increase rate that increase with the feed intake of chicken group after dispensing, broken rate of eggshell fall is for judgment basis, carry out the calculating of efficiency index afterwards according to indices weight aborning, formula is as follows: the dead mortality fall × 15%+ laying rate increase rate × 15%+ broken rate of eggshell fall × 10%=efficiency index of the amplitude that feed intake increases × 60%+.
Each group of therapeutic effect is in table 2:
Table 2
The efficiency index of herbal mixture prepared by the present invention's four embodiments is maximum with the value of embodiment 1, the difference respectively organized with other is extremely remarkable, and its feed intake increasing degree is more than more than 10% simultaneously, and anti-heat stress of layer effect is obvious, there is clinical value, be defined as optimum proportioning combination.
Test 3
In order to verify the result of use of the present invention to broiler, make following verification experimental verification
The basic condition of test:
Test period is on August 15,24 days to 2014 July in 2014, and place is Jiangxia District, Wuhan City Qin Ye company, and temperature on average was 33 DEG C at that time.Select the assorted broiler 900 of 19 ages in days soil, wherein test chicken 800 be divided into 4 groups, each 200 of every group because there being 4 kinds of pharmaceutical formulations, contrast chicken 100, raises in same hen house and separates with glue mesh sheet, freely ventilating, freely drinking water, free choice feeding.Every day, institute's feed material was responsible for by special messenger, and performed food consumption record the same day.
Observation of curative effect:
Direct-fed in feedstuff admixed by medicine, and dosage is undertaken by 1% of complete feedstuff quality.The dead mortality fall of the amplitude increased with the feed intake of chicken group after dispensing, the weightening finish increasing degree of chicken, chicken is for judgment basis, carry out the calculating of efficiency index afterwards according to indices weight aborning, formula is as follows: the weightening finish increasing degree × 40%+ chicken death of amplitude × 40%+ chicken that feed intake increases eliminates minimizing amplitude × 20%=efficiency index.
Each group of therapeutic effect is in table 3:
Table 3
Herbal mixture prepared by the present invention's four embodiments has good effect in the use of broiler, but efficiency index is maximum with the value of embodiment 1, the difference respectively organized with other is extremely remarkable, its feed intake increasing degree is close to 10% simultaneously, the effect of anti-broiler heat stress is obvious, large to the using value of broiler production.Therefore determine that the formula of embodiment 1 is optimum proportioning combination.
The result of comprehensive above 4 embodiments is known, and the formula of 4 embodiments has good effect in the application aspect of broiler and layer anti-heat stress, has possessed corresponding practical value.Working condition change greatly in practice, therefore can according to practical situation selective gist.